GO:0000287 - magnesium ion binding GO:0046872 - metal ion binding GO:0030145 - manganese ion binding GO:0050661 - NADP binding GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0005515 - protein binding GO:0005507 - copper ion binding GO:0004450 - isocitrate dehydrogenase (NADP+) activity GO:0051287 - NAD binding GO:0016491 - oxidoreductase activity