BLASTX 7.6.2
Query= UN00265 /QuerySize=1365
(1364 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O81893|ITPK3_ARATH Inositol-tetrakisphosphate 1-kinase 3 OS=A... 460 2e-128
sp|Q9SUG3|ITPK2_ARATH Inositol-tetrakisphosphate 1-kinase 2 OS=A... 365 5e-100
sp|Q84Y01|ITPK1_MAIZE Inositol-tetrakisphosphate 1-kinase 1 OS=Z... 226 3e-058
sp|Q9SBA5|ITPK1_ARATH Inositol-tetrakisphosphate 1-kinase 1 OS=A... 214 2e-054
sp|Q7ZU91|ITPK1_DANRE Inositol-tetrakisphosphate 1-kinase OS=Dan... 112 6e-024
sp|Q13572|ITPK1_HUMAN Inositol-tetrakisphosphate 1-kinase OS=Hom... 112 7e-024
sp|Q8BYN3|ITPK1_MOUSE Inositol-tetrakisphosphate 1-kinase OS=Mus... 112 1e-023
sp|P0C0T1|ITPK1_BOVIN Inositol-tetrakisphosphate 1-kinase OS=Bos... 111 2e-023
sp|Q5F480|ITPK1_CHICK Inositol-tetrakisphosphate 1-kinase OS=Gal... 108 1e-022
sp|Q7SY78|ITPK1_XENLA Inositol-tetrakisphosphate 1-kinase OS=Xen... 107 2e-022
>sp|O81893|ITPK3_ARATH Inositol-tetrakisphosphate 1-kinase 3 OS=Arabidopsis
thaliana GN=ITPK3 PE=2 SV=3
Length = 391
Score = 460 bits (1181), Expect = 2e-128
Identities = 237/319 (74%), Positives = 271/319 (84%), Gaps = 10/319 (3%)
Frame = -1
Query: 1202 EEEEEEEDKMVPQGDGEVVVDTASSQQQQQ---QQEERLVIGYALTSKKKQSFLQPKLEL 1032
EE+EEEED++ VV +T Q QQ QQ+++LV+GYALTSKKK+SFLQPKLEL
Sbjct: 50 EEQEEEEDQV-------VVNETTPFQFQQPLFLQQQQKLVVGYALTSKKKKSFLQPKLEL 102
Query: 1031 LARKKGISFVSIDQDKPLSEQGPFDVVLHKLLGNEWHHVIQDYQQKHPEVTVLDPPGAIQ 852
LAR+KGI FV+ID ++PLSEQGPFDVVLHKLLG EW VI+DYQQKHPEVTVLDPPG+IQ
Sbjct: 103 LARRKGIFFVAIDLNRPLSEQGPFDVVLHKLLGKEWEEVIEDYQQKHPEVTVLDPPGSIQ 162
Query: 851 RIYNRQSMLQGLADLNLAECDGMICVPKQMVVLQDTTSSANEVAKAGLKFPLVAKPLLVD 672
RIYNRQSMLQG+ADL L++C G + VPKQMVVL+D+ +SA+ V +AGLKFPLVAKPL +D
Sbjct: 163 RIYNRQSMLQGMADLKLSDCSGSLFVPKQMVVLKDSAASADAVVEAGLKFPLVAKPLWID 222
Query: 671 GTAKSHQLFLAYDCLSLAELEPPLVLQEFVNHGGVLFKVFVVGDVIRVVRRFSLPNVSNV 492
GTAKSHQL+LAYD SLAEL+PPLVLQEFVNHGGV+FKVFVVGDVI+V+RRFSLPNVSN
Sbjct: 223 GTAKSHQLYLAYDRRSLAELDPPLVLQEFVNHGGVMFKVFVVGDVIKVMRRFSLPNVSNC 282
Query: 491 GKEKVAGVFQFPRVSSAAASVDKTDLDPRVAELPPKPLLEELVRELRSRLGLRLFNIDMI 312
K KV GVFQFPRVSSAAAS D DLDPRVAELPPKP LE LV+ELRS LGLRLFNIDMI
Sbjct: 283 EKAKVDGVFQFPRVSSAAASADNADLDPRVAELPPKPFLEALVKELRSLLGLRLFNIDMI 342
Query: 311 REHGSQDVFMSLT*TIFLG 255
REHGS++VF + F G
Sbjct: 343 REHGSKNVFYVIDINYFPG 361
Score = 67 bits (162), Expect = 3e-010
Identities = 28/35 (80%), Positives = 32/35 (91%)
Frame = -3
Query: 285 YVIDINYFPGYGKMPDYEQVFIDFFLGLAQAKHEK 181
YVIDINYFPGYGK+PDYEQVF+DFF LAQ K++K
Sbjct: 352 YVIDINYFPGYGKLPDYEQVFVDFFQNLAQVKYKK 386
>sp|Q9SUG3|ITPK2_ARATH Inositol-tetrakisphosphate 1-kinase 2 OS=Arabidopsis
thaliana GN=ITPK2 PE=2 SV=2
Length = 353
Score = 365 bits (936), Expect = 5e-100
Identities = 181/284 (63%), Positives = 227/284 (79%)
Frame = -1
Query: 1106 EERLVIGYALTSKKKQSFLQPKLELLARKKGISFVSIDQDKPLSEQGPFDVVLHKLLGNE 927
++ +++GYALTSKK +SFLQPKLE LAR KGI FV+IDQ+KPLSEQGPFD+VLHK +G E
Sbjct: 38 KKSIIVGYALTSKKIKSFLQPKLEGLARNKGILFVAIDQNKPLSEQGPFDIVLHKQIGKE 97
Query: 926 WHHVIQDYQQKHPEVTVLDPPGAIQRIYNRQSMLQGLADLNLAECDGMICVPKQMVVLQD 747
W ++++++ HP+VTVLDPP AI + NRQSMLQ +AD+NL++ +G + VPKQ+V+ +D
Sbjct: 98 WRRILEEFRLAHPDVTVLDPPDAILHLRNRQSMLQCVADMNLSDSNGRVGVPKQLVIKKD 157
Query: 746 TTSSANEVAKAGLKFPLVAKPLLVDGTAKSHQLFLAYDCLSLAELEPPLVLQEFVNHGGV 567
+S V AGL+ PLVAKPL+ DG+AKSH+L LAYD SL +LEPPLVLQEFVNHGGV
Sbjct: 158 ASSIPEAVNNAGLRLPLVAKPLVADGSAKSHELSLAYDQHSLLKLEPPLVLQEFVNHGGV 217
Query: 566 LFKVFVVGDVIRVVRRFSLPNVSNVGKEKVAGVFQFPRVSSAAASVDKTDLDPRVAELPP 387
LFKV++VG+ IRVVRRFSLP+VS K AGVF+FPRVS AAAS D DLDP +AELPP
Sbjct: 218 LFKVYIVGEAIRVVRRFSLPDVSRRELPKSAGVFRFPRVSCAAASADDADLDPSIAELPP 277
Query: 386 KPLLEELVRELRSRLGLRLFNIDMIREHGSQDVFMSLT*TIFLG 255
+PLLE L +ELR LGLRLFN+D+IREHG++D F + F G
Sbjct: 278 RPLLERLAKELRRGLGLRLFNLDIIREHGTRDRFYVIDINYFPG 321
Score = 57 bits (137), Expect = 2e-007
Identities = 24/35 (68%), Positives = 29/35 (82%)
Frame = -3
Query: 285 YVIDINYFPGYGKMPDYEQVFIDFFLGLAQAKHEK 181
YVIDINYFPGYGKMP+YE VF DF L + Q++ +K
Sbjct: 312 YVIDINYFPGYGKMPEYEHVFTDFLLSVVQSQCKK 346
>sp|Q84Y01|ITPK1_MAIZE Inositol-tetrakisphosphate 1-kinase 1 OS=Zea mays
GN=ITPK1 PE=2 SV=1
Length = 342
Score = 226 bits (575), Expect = 3e-058
Identities = 128/303 (42%), Positives = 182/303 (60%), Gaps = 10/303 (3%)
Frame = -1
Query: 1142 DTASSQQQQQQQEERLVIGYALTSKKKQSFLQPKLELLARKKGISFVSIDQDKPLSEQGP 963
D A+ R VIGYAL KK+QSF+QP L A +G+ V +D +PL+EQGP
Sbjct: 4 DAAAEPSSGVTHPPRYVIGYALAPKKQQSFIQPSLVAQAASRGMDLVPVDASQPLAEQGP 63
Query: 962 FDVVLHKLLGNEWHHVIQDYQQKHPEVTVLDPPGAIQRIYNRQSMLQGLADL-NLAECDG 786
F +++HKL G++W + + +HP V ++DPP AI R++NR SMLQ +++L + A+ D
Sbjct: 64 FHLLIHKLYGDDWRAQLVAFAARHPAVPIVDPPHAIDRLHNRISMLQVVSELDHAADQDS 123
Query: 785 MICVPKQMVVLQDTTSSANEVAKAGLKFPLVAKPLLVDGTAKSHQLFLAYDCLSLAELEP 606
+P Q VV+ D + A+ A L+FPL+AKPL+ DGTAKSH++ L Y L +L P
Sbjct: 124 TFGIPSQ-VVVYDAAALADFGLLAALRFPLIAKPLVADGTAKSHKMSLVYHREGLGKLRP 182
Query: 605 PLVLQEFVNHGGVLFKVFVVGDVIRVVRRFSLPNVSNVGKEKVAGVFQFPRVS------S 444
PLVLQEFVNHGGV+FKV+VVG + V+R SLP+VS G F +VS +
Sbjct: 183 PLVLQEFVNHGGVIFKVYVVGGHVTCVKRRSLPDVSPEDDASAQGSVSFSQVSNLPTERT 242
Query: 443 AAASVDKTDLDPRVAELPPKPLLEELVRELRSRLGLRLFNIDMIREHGSQDVFMSLT*TI 264
A + L+ V +PP + ++ LR LGL+LFN DMIR+ + D ++ +
Sbjct: 243 AEEYYGEKSLEDAV--VPPAAFINQIAGGLRRALGLQLFNFDMIRDVRAGDRYLVIDINY 300
Query: 263 FLG 255
F G
Sbjct: 301 FPG 303
>sp|Q9SBA5|ITPK1_ARATH Inositol-tetrakisphosphate 1-kinase 1 OS=Arabidopsis
thaliana GN=ITPK1 PE=2 SV=1
Length = 319
Score = 214 bits (543), Expect = 2e-054
Identities = 118/290 (40%), Positives = 174/290 (60%), Gaps = 7/290 (2%)
Frame = -1
Query: 1106 EERLVIGYALTSKKKQSFLQPKLELLARKKGISFVSIDQDKPLSEQGPFDVVLHKLLGNE 927
+ER ++GYAL +KK+ SF+QP L +R++GI V +D K L EQG D ++HKL
Sbjct: 6 QERYLVGYALAAKKQHSFIQPSLIEHSRQRGIDLVKLDPTKSLLEQGKLDCIIHKLYDVY 65
Query: 926 WHHVIQDYQQKHPEVTVLDPPGAIQRIYNRQSMLQGLADLNLAECDG-MICVPKQMVVLQ 750
W + ++++K P V V+D P AI+R++NR SML+ + L D VP+Q+VV+
Sbjct: 66 WKENLHEFREKCPGVPVIDLPEAIERLHNRVSMLEVITQLRFPVSDSERFGVPEQVVVMD 125
Query: 749 DTTSSANEVAKAGLKFPLVAKPLLVDGTAKSHQLFLAYDCLSLAELEPPLVLQEFVNHGG 570
+ S A LKFP++AKPL DG+AKSH++FL YD + L+ P+VLQEFVNHGG
Sbjct: 126 SSVLSGGG-ALGELKFPVIAKPLDADGSAKSHKMFLIYDQEGMKILKAPIVLQEFVNHGG 184
Query: 569 VLFKVFVVGDVIRVVRRFSLPNVSNVGKEKVAGVFQFPRVSSAAASVDKT-----DLDPR 405
V+FKV+VVGD ++ V+R SLP++S G F ++S+ A DK D
Sbjct: 185 VIFKVYVVGDHVKCVKRRSLPDISEEKIGTSKGSLPFSQISNLTAQEDKNIEYGEDRSLE 244
Query: 404 VAELPPKPLLEELVRELRSRLGLRLFNIDMIREHGSQDVFMSLT*TIFLG 255
E+PP L +L + +R +GL LFN D+IR+ + ++ + F G
Sbjct: 245 KVEMPPLSFLTDLAKAMRESMGLNLFNFDVIRDAKDANRYLIIDINYFPG 294
>sp|Q7ZU91|ITPK1_DANRE Inositol-tetrakisphosphate 1-kinase OS=Danio rerio
GN=itpk1 PE=2 SV=2
Length = 396
Score = 112 bits (280), Expect = 6e-024
Identities = 69/204 (33%), Positives = 110/204 (53%), Gaps = 4/204 (1%)
Frame = -1
Query: 914 IQDYQQKHPEVTVLDPPGAIQRIYNRQSMLQGLADLNLAECDGMICVPKQMVVLQDT-TS 738
+QDY HPE +LDP AI+ + +R + + L + D IC P MV+ +
Sbjct: 81 VQDYIDAHPETVILDPLPAIRTLLDRCKSYKLIHKLEHSMEDDRICSPPFMVLKTECGFE 140
Query: 737 SANEVAKAGLKFPLVAKPLLVDGTAKSHQLFLAYDCLSLAELEPPLVLQEFVNHGGVLFK 558
+ ++ K G+ FP + KP + GT SH++ + + L +++PP VLQ F+NH VL+K
Sbjct: 141 TLEQLHKHGITFPFICKPQVAHGT-NSHEMAIIFSEEDLKDIKPPCVLQSFINHNAVLYK 199
Query: 557 VFVVGDVIRVVRRFSLPNVSNVGKEKVAGVFQFPRVSSAAASVDKTDLDPRVAE--LPPK 384
VFVVG+ VV+R S+ N + ++ A F VS +S T D V + P
Sbjct: 200 VFVVGEAYSVVQRPSIRNFPSGPTDRRAISFNSHHVSKPESSSHLTCRDNMVGQSWKPSN 259
Query: 383 PLLEELVRELRSRLGLRLFNIDMI 312
+++++ R+L LG+ LF ID+I
Sbjct: 260 EVIQKISRKLHQALGISLFGIDII 283
>sp|Q13572|ITPK1_HUMAN Inositol-tetrakisphosphate 1-kinase OS=Homo sapiens
GN=ITPK1 PE=1 SV=2
Length = 414
Score = 112 bits (279), Expect = 7e-024
Identities = 76/208 (36%), Positives = 107/208 (51%), Gaps = 8/208 (3%)
Frame = -1
Query: 920 HVIQDYQQKHPEVTVLDPPGAIQRIYNRQSMLQGLADLNLAECDGMICVPKQMVVLQ--- 750
H Q+Y HPE VLDP AI+ + +R + + + D IC P M +
Sbjct: 79 HRFQEYIDAHPETIVLDPLPAIRTLLDRSKSYELIRKIEAYMEDDRICSPPFMELTSLCG 138
Query: 749 DTTSSANEVAKAGLKFPLVAKPLLVDGTAKSHQLFLAYDCLSLAELEPPLVLQEFVNHGG 570
D T E K GL FP + K + GT SH++ + ++ L ++PP V+Q F+NH
Sbjct: 139 DDTMRLLE--KNGLTFPFICKTRVAHGT-NSHEMAIVFNQEGLNAIQPPCVVQNFINHNA 195
Query: 569 VLFKVFVVGDVIRVVRRFSLPNVSNVGKEKVAGVFQFPRVSSAAASVDKTDLD--PRVAE 396
VL+KVFVVG+ VV+R SL N S ++ + F VS +S T+LD V E
Sbjct: 196 VLYKVFVVGESYTVVQRPSLKNFSAGTSDRESIFFNSHNVSKPESSSVLTELDKIEGVFE 255
Query: 395 LPPKPLLEELVRELRSRLGLRLFNIDMI 312
P ++ EL R LR LG+ LF ID+I
Sbjct: 256 RPSDEVIRELSRALRQALGVSLFGIDII 283
>sp|Q8BYN3|ITPK1_MOUSE Inositol-tetrakisphosphate 1-kinase OS=Mus musculus
GN=Itpk1 PE=2 SV=1
Length = 419
Score = 112 bits (278), Expect = 1e-023
Identities = 75/210 (35%), Positives = 108/210 (51%), Gaps = 12/210 (5%)
Frame = -1
Query: 920 HVIQDYQQKHPEVTVLDPPGAIQRIYNRQSMLQGLADLNLAECDGMICVPKQMVVLQDTT 741
H Q+Y HPE VLDP AI+ + +R + + + D IC P M + T
Sbjct: 79 HRFQEYIDAHPETIVLDPLPAIRTLLDRSKSYELIRKIEAYMKDDRICSPPFM----ELT 134
Query: 740 SSANE-----VAKAGLKFPLVAKPLLVDGTAKSHQLFLAYDCLSLAELEPPLVLQEFVNH 576
S E + + GL FP + K + GT SH++ + ++ L ++PP V+Q F+NH
Sbjct: 135 SLCGEDTMRLLEQNGLAFPFICKTRVAHGT-NSHEMAIVFNQEGLNAIQPPCVVQNFINH 193
Query: 575 GGVLFKVFVVGDVIRVVRRFSLPNVSNVGKEKVAGVFQFPRVSSAAASVDKTDLD--PRV 402
VL+KVFVVG+ VV+R SL N S ++ + F VS +S T+LD V
Sbjct: 194 NAVLYKVFVVGESYTVVQRPSLKNFSAGTSDRESIFFNSHNVSKPESSSVLTELDKIEGV 253
Query: 401 AELPPKPLLEELVRELRSRLGLRLFNIDMI 312
E P ++ EL R LR LG+ LF ID+I
Sbjct: 254 FERPSDEVIRELSRALRQALGVSLFGIDII 283
>sp|P0C0T1|ITPK1_BOVIN Inositol-tetrakisphosphate 1-kinase OS=Bos taurus
GN=ITPK1 PE=1 SV=1
Length = 419
Score = 111 bits (275), Expect = 2e-023
Identities = 75/208 (36%), Positives = 107/208 (51%), Gaps = 8/208 (3%)
Frame = -1
Query: 920 HVIQDYQQKHPEVTVLDPPGAIQRIYNRQSMLQGLADLNLAECDGMICVPKQMVVLQ--- 750
H Q+Y HPE VLDP AI+ + +R + + + D IC P M +
Sbjct: 79 HRFQEYIDAHPETIVLDPLPAIRTLLDRSKSYELIRKIEAYMKDDRICSPPFMELTSLCG 138
Query: 749 DTTSSANEVAKAGLKFPLVAKPLLVDGTAKSHQLFLAYDCLSLAELEPPLVLQEFVNHGG 570
D T E + GL FP + K + GT SH++ + ++ L+ ++PP V+Q F+NH
Sbjct: 139 DDTMRLLE--ENGLAFPFICKTRVAHGT-NSHEMAIVFNQEGLSAIQPPCVVQNFINHNA 195
Query: 569 VLFKVFVVGDVIRVVRRFSLPNVSNVGKEKVAGVFQFPRVSSAAASVDKTDLD--PRVAE 396
VL+KVFVVG+ VV+R SL N S ++ + F VS +S T LD V E
Sbjct: 196 VLYKVFVVGESYTVVQRPSLKNFSAGTSDRESIFFNSHNVSKPESSSVLTALDKIEGVFE 255
Query: 395 LPPKPLLEELVRELRSRLGLRLFNIDMI 312
P ++ EL R LR LG+ LF ID+I
Sbjct: 256 RPSDEVIRELSRALRQALGVSLFGIDII 283
>sp|Q5F480|ITPK1_CHICK Inositol-tetrakisphosphate 1-kinase OS=Gallus gallus
GN=ITPK1 PE=2 SV=1
Length = 407
Score = 108 bits (269), Expect = 1e-022
Identities = 72/207 (34%), Positives = 106/207 (51%), Gaps = 12/207 (5%)
Frame = -1
Query: 911 QDYQQKHPEVTVLDPPGAIQRIYNRQSMLQGLADLNLAECDGMICVPKQMVVLQDTTSSA 732
Q+Y HPE +LDP AI+ + +R + + + D IC P M + TS+
Sbjct: 82 QEYIDAHPETIILDPLPAIRTLLDRSKSYELIRQIEAYMQDERICSPPFM----ELTSAC 137
Query: 731 NE-----VAKAGLKFPLVAKPLLVDGTAKSHQLFLAYDCLSLAELEPPLVLQEFVNHGGV 567
E + K GL FP + K + GT SH++ + ++ L + PP V+Q F+NH V
Sbjct: 138 GEDTLQLIEKNGLAFPFICKTRVAHGT-NSHEMAIIFNQEGLKAVRPPCVIQSFINHNAV 196
Query: 566 LFKVFVVGDVIRVVRRFSLPNVSNVGKEKVAGVFQFPRVSSAAASVDKTDLD--PRVAEL 393
L+KVFVVG+ VV+R SL N S ++ + F VS +S T LD V E
Sbjct: 197 LYKVFVVGESYTVVKRPSLKNFSAGISDRESIFFNSHNVSKPESSSVLTALDKIEGVFER 256
Query: 392 PPKPLLEELVRELRSRLGLRLFNIDMI 312
P ++ E+ + LR LG+ LF ID+I
Sbjct: 257 PDDDVIREISKALRQALGVSLFGIDII 283
>sp|Q7SY78|ITPK1_XENLA Inositol-tetrakisphosphate 1-kinase OS=Xenopus laevis
GN=itpk1 PE=2 SV=1
Length = 396
Score = 107 bits (266), Expect = 2e-022
Identities = 69/203 (33%), Positives = 106/203 (52%), Gaps = 4/203 (1%)
Frame = -1
Query: 911 QDYQQKHPEVTVLDPPGAIQRIYNRQSMLQGLADLNLAECDGMICVPKQMVVLQDTTSSA 732
QDY + HPE +LDP AI+ + +R + + + D IC P M ++ +
Sbjct: 82 QDYIEAHPETIILDPLPAIRTLLDRSKSYELIRRIETYMQDERICSPPFMELMAECDEDT 141
Query: 731 NEV-AKAGLKFPLVAKPLLVDGTAKSHQLFLAYDCLSLAELEPPLVLQEFVNHGGVLFKV 555
++ K GL FPLV K + GT SH++ + ++ L ++PP V+Q F++H VL+KV
Sbjct: 142 LKILEKNGLAFPLVCKTRVAHGT-NSHEMAIIFNPEGLWSIKPPCVIQSFISHNAVLYKV 200
Query: 554 FVVGDVIRVVRRFSLPNVSNVGKEKVAGVFQFPRVSSAAASVDKTDLD--PRVAELPPKP 381
FVVG+ VV R SL N S ++ + F VS +S T L+ V E P
Sbjct: 201 FVVGESYTVVERPSLKNFSLGASDRASIFFNSHNVSKPESSSVLTALEKVEGVFERPCDE 260
Query: 380 LLEELVRELRSRLGLRLFNIDMI 312
++ + + LR LG+ LF ID+I
Sbjct: 261 VIRGISKALRQALGISLFGIDII 283
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,050,399,196
Number of Sequences: 518415
Number of Extensions: 1050399196
Number of Successful Extensions: 12515467
Number of sequences better than 0.0: 0
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