BLASTX 7.6.2
Query= UN00404 /QuerySize=1156
(1155 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5R8U1|GALM_PONAB Aldose 1-epimerase OS=Pongo abelii GN=GALM ... 141 1e-032
sp|Q5EA79|GALM_BOVIN Aldose 1-epimerase OS=Bos taurus GN=GALM PE... 137 2e-031
sp|Q96C23|GALM_HUMAN Aldose 1-epimerase OS=Homo sapiens GN=GALM ... 137 2e-031
sp|Q8K157|GALM_MOUSE Aldose 1-epimerase OS=Mus musculus GN=Galm ... 136 3e-031
sp|Q66HG4|GALM_RAT Aldose 1-epimerase OS=Rattus norvegicus GN=Ga... 132 5e-030
sp|Q9GKX6|GALM_PIG Aldose 1-epimerase OS=Sus scrofa GN=GALM PE=2... 131 1e-029
sp|P05149|GALM_ACICA Aldose 1-epimerase OS=Acinetobacter calcoac... 111 2e-023
sp|P31765|GALM_HAEIN Aldose 1-epimerase OS=Haemophilus influenza... 65 8e-010
sp|P0A9C3|GALM_ECOLI Aldose 1-epimerase OS=Escherichia coli (str... 54 2e-006
sp|P21955|GALM_STRTR Aldose 1-epimerase OS=Streptococcus thermop... 52 6e-006
>sp|Q5R8U1|GALM_PONAB Aldose 1-epimerase OS=Pongo abelii GN=GALM PE=2 SV=1
Length = 342
Score = 141 bits (354), Expect = 1e-032
Identities = 70/164 (42%), Positives = 100/164 (60%), Gaps = 4/164 (2%)
Frame = +3
Query: 525 WNLHGHNSGDILSHKIQLLAKKITPVDEELIPTGEITSIEGTPYDFLEPREIGGRIHELP 704
+NL G S +I H++ + A PVDE LIPTGE+ ++GT +D +P E+G + +
Sbjct: 179 FNLAGQGSPNIYDHEVTIEADTYLPVDETLIPTGEVAPVQGTAFDLRKPVELGKHLQDFH 238
Query: 705 -GGYDINYVIEGKAGKHLRKTAVVSEGVSGRKMELWSNQPGVQFYMSNLLKSVV-GKGNA 878
G+D N+ ++G KH A V SGR +E+++ QPGVQFYM N L + GK A
Sbjct: 239 LNGFDHNFCLKGSKEKHF--CARVHHAASGRVLEVYTTQPGVQFYMGNFLDGTLKGKNGA 296
Query: 879 VYKKYAGLCLETQGFPDSVNHKNFPSQIVNPGESYLHVMLFRFT 1010
VY K++G CLETQ +PD+VN FP ++ PGE Y H F+F+
Sbjct: 297 VYPKHSGFCLETQNWPDAVNQPRFPPVLLRPGEEYDHTTWFKFS 340
Score = 61 bits (147), Expect = 1e-008
Identities = 38/100 (38%), Positives = 59/100 (59%), Gaps = 10/100 (10%)
Frame = +3
Query: 324 GRVANRIGGAKFKLNGQLYKTDANEGHNTLHGGSKGFSDVIWSVENYVPTSHITFKYHSF 503
GRVANRI FK++G+ Y N+ N+LHGG +GF V+W+ V ++ I F S
Sbjct: 77 GRVANRIAKGTFKVDGKEYHLAINKEPNSLHGGVRGFDKVLWTPR--VLSNGIQFSRISP 134
Query: 504 DGEEGFP-----WNLHGHNSGD-ILSHKIQLLAKKITPVD 605
DGEEG+P W + + G+ +++++ Q A + TPV+
Sbjct: 135 DGEEGYPGELKVWVTYTLDGGELVVNYRAQ--ASQATPVN 172
>sp|Q5EA79|GALM_BOVIN Aldose 1-epimerase OS=Bos taurus GN=GALM PE=2 SV=1
Length = 342
Score = 137 bits (344), Expect = 2e-031
Identities = 74/182 (40%), Positives = 106/182 (58%), Gaps = 11/182 (6%)
Frame = +3
Query: 471 TSHITFKYHSFDGEEGFPWNLHGHNSGDILSHKIQLLAKKITPVDEELIPTGEITSIEGT 650
T+ + HS+ +NL G S +I H++ + A PVDE LIPTGEI S++GT
Sbjct: 168 TTPVNLTNHSY-------FNLAGQGSPNIYDHEVTIEADAFLPVDEVLIPTGEIASVQGT 220
Query: 651 PYDFLEPREIGGRIHEL-PGGYDINYVIEGKAGKHLRKTAVVSEGVSGRKMELWSNQPGV 827
+D +P E+G + E G+D N+ ++G K R A V SGR +E+++ QPGV
Sbjct: 221 AFDLRKPVELGKHLQEFHVNGFDHNFCLKG--SKEKRFCARVHHAGSGRVLEVYTTQPGV 278
Query: 828 QFYMSNLLKSVV-GKGNAVYKKYAGLCLETQGFPDSVNHKNFPSQIVNPGESYLHVMLFR 1004
QFY N L + GK A Y K++G CLETQ +PD+VN +FP ++ PGE Y H F+
Sbjct: 279 QFYTGNFLDGTLKGKSGAGYPKHSGFCLETQSWPDAVNQPHFPPVLLKPGEEYDHTTWFK 338
Query: 1005 FT 1010
F+
Sbjct: 339 FS 340
Score = 67 bits (162), Expect = 2e-010
Identities = 40/100 (40%), Positives = 60/100 (60%), Gaps = 10/100 (10%)
Frame = +3
Query: 324 GRVANRIGGAKFKLNGQLYKTDANEGHNTLHGGSKGFSDVIWSVENYVPTSHITFKYHSF 503
GRVANRI F L+G+ YK N G N+LHGG KGF V+W+ V ++ + F S
Sbjct: 77 GRVANRIAKGTFTLDGKEYKLAINNGPNSLHGGVKGFDKVLWTPR--VLSNGVEFSRVSP 134
Query: 504 DGEEGFP-----WNLHGHNSGD-ILSHKIQLLAKKITPVD 605
DGEEG+P W ++ + G+ +++++ Q A + TPV+
Sbjct: 135 DGEEGYPGELKVWVMYTLDGGELVVNYRAQ--ASQTTPVN 172
>sp|Q96C23|GALM_HUMAN Aldose 1-epimerase OS=Homo sapiens GN=GALM PE=1 SV=1
Length = 342
Score = 137 bits (344), Expect = 2e-031
Identities = 69/164 (42%), Positives = 99/164 (60%), Gaps = 4/164 (2%)
Frame = +3
Query: 525 WNLHGHNSGDILSHKIQLLAKKITPVDEELIPTGEITSIEGTPYDFLEPREIGGRIHELP 704
+NL G S +I H++ + A PVDE LIPTGE+ ++GT +D +P E+G + +
Sbjct: 179 FNLAGQASPNINDHEVTIEADTYLPVDETLIPTGEVAPVQGTAFDLRKPVELGKHLQDFH 238
Query: 705 -GGYDINYVIEGKAGKHLRKTAVVSEGVSGRKMELWSNQPGVQFYMSNLLKSVV-GKGNA 878
G+D N+ ++G KH A V SGR +E+++ QPGVQFY N L + GK A
Sbjct: 239 LNGFDHNFCLKGSKEKHF--CARVHHAASGRVLEVYTTQPGVQFYTGNFLDGTLKGKNGA 296
Query: 879 VYKKYAGLCLETQGFPDSVNHKNFPSQIVNPGESYLHVMLFRFT 1010
VY K++G CLETQ +PD+VN FP ++ PGE Y H F+F+
Sbjct: 297 VYPKHSGFCLETQNWPDAVNQPRFPPVLLRPGEEYDHTTWFKFS 340
Score = 61 bits (147), Expect = 1e-008
Identities = 38/100 (38%), Positives = 59/100 (59%), Gaps = 10/100 (10%)
Frame = +3
Query: 324 GRVANRIGGAKFKLNGQLYKTDANEGHNTLHGGSKGFSDVIWSVENYVPTSHITFKYHSF 503
GRVANRI FK++G+ Y N+ N+LHGG +GF V+W+ V ++ + F S
Sbjct: 77 GRVANRIAKGTFKVDGKEYHLAINKEPNSLHGGVRGFDKVLWTPR--VLSNGVQFSRISP 134
Query: 504 DGEEGFP-----WNLHGHNSGD-ILSHKIQLLAKKITPVD 605
DGEEG+P W + + G+ I++++ Q A + TPV+
Sbjct: 135 DGEEGYPGELKVWVTYTLDGGELIVNYRAQ--ASQATPVN 172
>sp|Q8K157|GALM_MOUSE Aldose 1-epimerase OS=Mus musculus GN=Galm PE=2 SV=1
Length = 342
Score = 136 bits (342), Expect = 3e-031
Identities = 74/182 (40%), Positives = 104/182 (57%), Gaps = 11/182 (6%)
Frame = +3
Query: 471 TSHITFKYHSFDGEEGFPWNLHGHNSGDILSHKIQLLAKKITPVDEELIPTGEITSIEGT 650
T+ + HS+ +NL G S +I H++ + A PVDE LIPTG I +EGT
Sbjct: 168 TTPVNLTNHSY-------FNLAGQGSPNIYDHEVTIAADAYLPVDETLIPTGVIAPVEGT 220
Query: 651 PYDFLEPREIGGRIHELP-GGYDINYVIEGKAGKHLRKTAVVSEGVSGRKMELWSNQPGV 827
+D +P E+G + + G+D N+ + K K + A V SGR +E+++ QPGV
Sbjct: 221 AFDLRKPVELGTHLQDYHIHGFDHNFCL--KESKEKKFCARVRHAASGRILEVYTTQPGV 278
Query: 828 QFYMSNLLKSVV-GKGNAVYKKYAGLCLETQGFPDSVNHKNFPSQIVNPGESYLHVMLFR 1004
QFY N L + GK AVY K++GLCLETQ +PDSVN FP ++ PGE Y H F+
Sbjct: 279 QFYTGNFLDGTLKGKNGAVYPKHSGLCLETQNWPDSVNQPQFPPALLRPGEEYNHTTWFK 338
Query: 1005 FT 1010
F+
Sbjct: 339 FS 340
Score = 60 bits (145), Expect = 2e-008
Identities = 37/100 (37%), Positives = 57/100 (57%), Gaps = 10/100 (10%)
Frame = +3
Query: 324 GRVANRIGGAKFKLNGQLYKTDANEGHNTLHGGSKGFSDVIWSVENYVPTSHITFKYHSF 503
GRVANRI +F + G+ Y N N+LHGG GF V+W+ + V T+ + F S
Sbjct: 77 GRVANRIAKGRFTIGGKEYHLPVNREPNSLHGGFTGFDKVLWTPQ--VLTNGVQFFRVSP 134
Query: 504 DGEEGFP-----WNLHGHNSGD-ILSHKIQLLAKKITPVD 605
DGEEG+P W + + G+ +++++ Q A + TPV+
Sbjct: 135 DGEEGYPGELKVWVTYTLDGGELVINYRAQ--ASQTTPVN 172
>sp|Q66HG4|GALM_RAT Aldose 1-epimerase OS=Rattus norvegicus GN=Galm PE=1 SV=1
Length = 342
Score = 132 bits (331), Expect = 5e-030
Identities = 72/182 (39%), Positives = 101/182 (55%), Gaps = 11/182 (6%)
Frame = +3
Query: 471 TSHITFKYHSFDGEEGFPWNLHGHNSGDILSHKIQLLAKKITPVDEELIPTGEITSIEGT 650
T+ + HS+ +NL G S DI H++ + A PVDE LIPTG I +EGT
Sbjct: 168 TTPVNLTNHSY-------FNLAGQGSPDIYDHEVTIAADAYLPVDETLIPTGVIAPVEGT 220
Query: 651 PYDFLEPREIGGRIHELP-GGYDINYVIEGKAGKHLRKTAVVSEGVSGRKMELWSNQPGV 827
+D +P E+G + G+D N+ + K K + A V SGR +E+++ QPGV
Sbjct: 221 AFDLRKPVELGKHLQSYHIHGFDHNFCL--KESKEKKFCARVHHAASGRILEVYTTQPGV 278
Query: 828 QFYMSNLLKSVV-GKGNAVYKKYAGLCLETQGFPDSVNHKNFPSQIVNPGESYLHVMLFR 1004
QFY N L + GK VY K++G CLETQ +PD+VN FP ++ PGE Y H F+
Sbjct: 279 QFYTGNFLDGTLKGKSGEVYPKHSGFCLETQNWPDAVNQPQFPPILLRPGEEYNHTTWFK 338
Query: 1005 FT 1010
F+
Sbjct: 339 FS 340
Score = 60 bits (145), Expect = 2e-008
Identities = 36/100 (36%), Positives = 59/100 (59%), Gaps = 10/100 (10%)
Frame = +3
Query: 324 GRVANRIGGAKFKLNGQLYKTDANEGHNTLHGGSKGFSDVIWSVENYVPTSHITFKYHSF 503
GRVANRI +F ++G+ Y N N+LHGG +GF V+W+ + V ++ + F S
Sbjct: 77 GRVANRIAKGRFTVDGKEYHLPINREPNSLHGGFRGFDKVLWTPQ--VLSNGVQFSRVSP 134
Query: 504 DGEEGFP-----WNLHGHNSGD-ILSHKIQLLAKKITPVD 605
DGEEG+P W + + G+ +++++ Q A + TPV+
Sbjct: 135 DGEEGYPGELKVWVTYTLDGGELVVNYRAQ--ASQTTPVN 172
>sp|Q9GKX6|GALM_PIG Aldose 1-epimerase OS=Sus scrofa GN=GALM PE=2 SV=1
Length = 342
Score = 131 bits (328), Expect = 1e-029
Identities = 71/182 (39%), Positives = 104/182 (57%), Gaps = 11/182 (6%)
Frame = +3
Query: 471 TSHITFKYHSFDGEEGFPWNLHGHNSGDILSHKIQLLAKKITPVDEELIPTGEITSIEGT 650
T+ + HS+ +NL G S +I H++ + A PVDE LIPTGEI ++GT
Sbjct: 168 TTPVNLTNHSY-------FNLAGQGSPNIYDHEVTIEADAFLPVDETLIPTGEIAPVQGT 220
Query: 651 PYDFLEPREIGGRIHELP-GGYDINYVIEGKAGKHLRKTAVVSEGVSGRKMELWSNQPGV 827
+D +P E+G + E G+D N+ + K K + A V SGR +E+++ QPG+
Sbjct: 221 AFDLRKPVELGKHLQEFHINGFDHNFCL--KRSKEKQFCARVHHAGSGRVLEVYTTQPGI 278
Query: 828 QFYMSNLLKSVV-GKGNAVYKKYAGLCLETQGFPDSVNHKNFPSQIVNPGESYLHVMLFR 1004
QFY N L + GK AVY K++G CLETQ +P++VN +FP ++ PGE Y H F
Sbjct: 279 QFYTGNFLDGTLKGKTGAVYPKHSGFCLETQNWPNAVNQPHFPPVLLKPGEEYNHTTWFV 338
Query: 1005 FT 1010
F+
Sbjct: 339 FS 340
Score = 65 bits (157), Expect = 8e-010
Identities = 40/100 (40%), Positives = 59/100 (59%), Gaps = 10/100 (10%)
Frame = +3
Query: 324 GRVANRIGGAKFKLNGQLYKTDANEGHNTLHGGSKGFSDVIWSVENYVPTSHITFKYHSF 503
GRVANRI F L+G+ YK N G N+LHGG +GF V+W+ V ++ I F S
Sbjct: 77 GRVANRIAKGTFTLDGKEYKLAINNGPNSLHGGVRGFDKVLWTPR--VLSNGIEFSRVSP 134
Query: 504 DGEEGFP-----WNLHGHNSGD-ILSHKIQLLAKKITPVD 605
DGEEG+P W + + G+ +++++ Q A + TPV+
Sbjct: 135 DGEEGYPGELKVWVTYTLDGGELVVNYRAQ--ASQTTPVN 172
>sp|P05149|GALM_ACICA Aldose 1-epimerase OS=Acinetobacter calcoaceticus GN=mro
PE=1 SV=1
Length = 381
Score = 111 bits (275), Expect = 2e-023
Identities = 63/164 (38%), Positives = 92/164 (56%), Gaps = 7/164 (4%)
Frame = +3
Query: 537 GHNSGDILSHKIQLLAKKITPVDEELIPTGEITSIEGTPYDFLEPREIGGRIH------E 698
G+N +L H +QL A +I D+ +PTGEI S+ GTP+DF P+ I I
Sbjct: 214 GNNPYGVLDHVVQLNAGRILVTDQNSLPTGEIASVAGTPFDFRMPKAIVKDIRANNQQLA 273
Query: 699 LPGGYDINYVIEGKAGKHLRKTAVVSEGVSGRKMELWSNQPGVQFYMS-NLLKSVVGKGN 875
GYD +VI K+ L A+V + S R M++ + +P VQ Y + +LL ++VG
Sbjct: 274 YGYGYDQTWVINQKSQGKLNLAAIVVDPKSKRTMQVLTTEPSVQMYTADHLLGNIVGANG 333
Query: 876 AVYKKYAGLCLETQGFPDSVNHKNFPSQIVNPGESYLHVMLFRF 1007
+Y++ L LETQ FPDS N FPS +NP ++Y V +F+F
Sbjct: 334 VLYRQADALALETQHFPDSPNQPTFPSTRLNPNQTYNSVTVFKF 377
Score = 64 bits (155), Expect = 1e-009
Identities = 39/101 (38%), Positives = 53/101 (52%), Gaps = 6/101 (5%)
Frame = +3
Query: 315 GNCGRVANRIGGAKFKLNGQLYKTDANEGHNTLHGGSKGFSDVIWSVENYV---PTSHIT 485
G GR ANRIG AKF L+G+ Y + N G N+LH G+ GF +W V+ V T +
Sbjct: 97 GLIGRYANRIGNAKFSLDGKTYNLEKNNGPNSLHSGNPGFDKRVWQVKPLVSKGETVKAS 156
Query: 486 FKYHSFDGEEGFPWNLHG---HNSGDILSHKIQLLAKKITP 599
K S +G++GFP L ++ D KI+ AK P
Sbjct: 157 LKLTSPNGDQGFPGKLDVEVIYSLSDQNEFKIEYKAKTDQP 197
>sp|P31765|GALM_HAEIN Aldose 1-epimerase OS=Haemophilus influenzae GN=galM PE=3
SV=2
Length = 340
Score = 65 bits (157), Expect = 8e-010
Identities = 31/70 (44%), Positives = 46/70 (65%), Gaps = 2/70 (2%)
Frame = +3
Query: 324 GRVANRIGGAKFKLNGQLYKTDANEGHNTLHGGSKGFSDVIWSVENYVPTSHITFKYHSF 503
GR ANRI A+F+LNG+L K +N+G + LHGG +GF W+++ + + F HS
Sbjct: 72 GRYANRIANAQFELNGELIKLSSNQGKHQLHGG-EGFDKRRWNIQE-CGENFVCFSLHSV 129
Query: 504 DGEEGFPWNL 533
DG++GFP N+
Sbjct: 130 DGDQGFPGNV 139
>sp|P0A9C3|GALM_ECOLI Aldose 1-epimerase OS=Escherichia coli (strain K12)
GN=galM PE=1 SV=1
Length = 346
Score = 54 bits (128), Expect = 2e-006
Identities = 26/70 (37%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
Frame = +3
Query: 324 GRVANRIGGAKFKLNGQLYKTDANEGHNTLHGGSKGFSDVIWSVENYVPTSHITFKYHSF 503
GR ANRI +++ +G+ ++G N LHGG +GF W + N + F S
Sbjct: 74 GRYANRIANSRYTFDGETVTLSPSQGVNQLHGGPEGFDKRRWQIVNQ-NDRQVLFALSSD 132
Query: 504 DGEEGFPWNL 533
DG++GFP NL
Sbjct: 133 DGDQGFPGNL 142
>sp|P21955|GALM_STRTR Aldose 1-epimerase OS=Streptococcus thermophilus GN=galM
PE=3 SV=1
Length = 348
Score = 52 bits (124), Expect = 6e-006
Identities = 31/70 (44%), Positives = 35/70 (50%), Gaps = 5/70 (7%)
Frame = +3
Query: 324 GRVANRIGGAKFKLNGQLYKTDANEGHNTLHGGSKGFSDVIWSV-----ENYVPTSHITF 488
GRVA RIG A + N LY NEG N LHGG KG W+ ++YV T I
Sbjct: 75 GRVAGRIGKASYTHNMVLYSLPKNEGDNCLHGGPKGMQVQNWNYVTNLNDDYVETKFIRR 134
Query: 489 KYHSFDGEEG 518
Y S DG G
Sbjct: 135 LYSSVDGFPG 144
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,097,078,157
Number of Sequences: 518415
Number of Extensions: 2097078157
Number of Successful Extensions: 32972734
Number of sequences better than 0.0: 0
|
