BLASTX 7.6.2
Query= UN00543 /QuerySize=887
(886 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q2KJ25|PSD12_BOVIN 26S proteasome non-ATPase regulatory subun... 192 4e-048
sp|O00232|PSD12_HUMAN 26S proteasome non-ATPase regulatory subun... 191 5e-048
sp|Q5RBI3|PSD12_PONAB 26S proteasome non-ATPase regulatory subun... 191 5e-048
sp|Q54UJ0|PSD12_DICDI 26S proteasome non-ATPase regulatory subun... 186 2e-046
sp|Q9D8W5|PSD12_MOUSE 26S proteasome non-ATPase regulatory subun... 186 2e-046
sp|Q9UTM3|RPN5_SCHPO 26S proteasome regulatory subunit rpn5 OS=S... 158 8e-038
sp|Q12250|RPN5_YEAST 26S proteasome regulatory subunit RPN5 OS=S... 151 1e-035
>sp|Q2KJ25|PSD12_BOVIN 26S proteasome non-ATPase regulatory subunit 12 OS=Bos
taurus GN=PSMD12 PE=2 SV=3
Length = 456
Score = 192 bits (486), Expect = 4e-048
Identities = 97/188 (51%), Positives = 135/188 (71%), Gaps = 1/188 (0%)
Frame = +2
Query: 104 GNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKKRGQL 283
G L+ I+ LL+ EKQ R A ++ T + I+++C+EAK+W LLNE I+ LSK+R QL
Sbjct: 38 GRLQEVIETLLSLEKQTRTASDMVSTSRILVAIVKMCYEAKEWDLLNENIMLLSKRRSQL 97
Query: 284 KQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIKEDQG 463
KQAV MVQQ Y+++ D+ ++ LI TL V+ GKIYVEIERARLT+ LA IKE G
Sbjct: 98 KQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNG 157
Query: 464 QIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKINPRVF-DA 640
+ EAA ++QE+ VET+G+M K E++ FILEQ+RLCL +DY+R QI+S+KIN + F +
Sbjct: 158 DVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEE 217
Query: 641 DTKKDKKK 664
+T+K K K
Sbjct: 218 NTEKLKLK 225
>sp|O00232|PSD12_HUMAN 26S proteasome non-ATPase regulatory subunit 12 OS=Homo
sapiens GN=PSMD12 PE=1 SV=3
Length = 456
Score = 191 bits (485), Expect = 5e-048
Identities = 96/188 (51%), Positives = 135/188 (71%), Gaps = 1/188 (0%)
Frame = +2
Query: 104 GNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKKRGQL 283
G L+ I+ LL+ EKQ R A ++ T + ++++C+EAK+W LLNE I+ LSK+R QL
Sbjct: 38 GRLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQL 97
Query: 284 KQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIKEDQG 463
KQAV MVQQ Y+++ D+ ++ LI TL V+ GKIYVEIERARLT+ LA IKE G
Sbjct: 98 KQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNG 157
Query: 464 QIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKINPRVF-DA 640
+ EAA ++QE+ VET+G+M K E++ FILEQ+RLCL +DY+R QI+S+KIN + F +
Sbjct: 158 DVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEE 217
Query: 641 DTKKDKKK 664
+T+K K K
Sbjct: 218 NTEKLKLK 225
>sp|Q5RBI3|PSD12_PONAB 26S proteasome non-ATPase regulatory subunit 12 OS=Pongo
abelii GN=PSMD12 PE=2 SV=3
Length = 456
Score = 191 bits (485), Expect = 5e-048
Identities = 96/188 (51%), Positives = 135/188 (71%), Gaps = 1/188 (0%)
Frame = +2
Query: 104 GNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKKRGQL 283
G L+ I+ LL+ EKQ R A ++ T + ++++C+EAK+W LLNE I+ LSK+R QL
Sbjct: 38 GRLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQL 97
Query: 284 KQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIKEDQG 463
KQAV MVQQ Y+++ D+ ++ LI TL V+ GKIYVEIERARLT+ LA IKE G
Sbjct: 98 KQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNG 157
Query: 464 QIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKINPRVF-DA 640
+ EAA ++QE+ VET+G+M K E++ FILEQ+RLCL +DY+R QI+S+KIN + F +
Sbjct: 158 DVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEE 217
Query: 641 DTKKDKKK 664
+T+K K K
Sbjct: 218 NTEKLKLK 225
>sp|Q54UJ0|PSD12_DICDI 26S proteasome non-ATPase regulatory subunit 12
OS=Dictyostelium discoideum GN=psmD12 PE=2 SV=1
Length = 447
Score = 186 bits (472), Expect = 2e-046
Identities = 89/190 (46%), Positives = 137/190 (72%)
Frame = +2
Query: 92 MGAGGNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKK 271
+ G L +I+ LL EKQ R AE+ T K A EI++LC+EA L+NE+++ LSK+
Sbjct: 35 LAKSGKLIEAIENLLITEKQCRQAEDSPSTSKIAAEIIKLCYEAGRLDLVNEKLVLLSKR 94
Query: 272 RGQLKQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIK 451
RGQL+ A++++VQ++M Y+DQ D++ ++ELI TL +S GKI+VE ERARLT+ L+KIK
Sbjct: 95 RGQLRPAIKAIVQESMVYVDQITDMKQKLELIDTLRTISDGKIFVENERARLTKTLSKIK 154
Query: 452 EDQGQIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKINPRV 631
ED+G IA AA ++Q++ VET+G M K EKI F ++Q+R+C++ +D++RAQ++ K+N +
Sbjct: 155 EDEGDIASAAKILQDLQVETYGTMEKREKITFFIDQMRICMNNKDFIRAQLIGNKVNRKT 214
Query: 632 FDADTKKDKK 661
D +D K
Sbjct: 215 LAEDENQDLK 224
>sp|Q9D8W5|PSD12_MOUSE 26S proteasome non-ATPase regulatory subunit 12 OS=Mus
musculus GN=Psmd12 PE=2 SV=3
Length = 456
Score = 186 bits (472), Expect = 2e-046
Identities = 91/186 (48%), Positives = 130/186 (69%)
Frame = +2
Query: 104 GNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKKRGQL 283
G L+ I+ LL+ EKQ R A ++ T + ++++C+EAK+W L NE I+ LSK+R QL
Sbjct: 38 GRLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLHNENIMLLSKRRSQL 97
Query: 284 KQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIKEDQG 463
KQAV MVQQ Y+++ D+ ++ LI TL V+ GKIYVEIERARLT+ LA IKE G
Sbjct: 98 KQAVAKMVQQCCTYVEEITDLPVKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNG 157
Query: 464 QIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKINPRVFDAD 643
+ EAA ++QE+ VET+G+M K E++ FILEQ+RLCL +DY+R QI+S+KIN + +
Sbjct: 158 DVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFSQEE 217
Query: 644 TKKDKK 661
++ K
Sbjct: 218 NTENMK 223
>sp|Q9UTM3|RPN5_SCHPO 26S proteasome regulatory subunit rpn5
OS=Schizosaccharomyces pombe GN=rpn5a PE=1 SV=1
Length = 443
Score = 158 bits (397), Expect = 8e-038
Identities = 82/185 (44%), Positives = 125/185 (67%)
Frame = +2
Query: 107 NLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKKRGQLK 286
+++A++++LL EKQ+R A + + K I L F A D++ LNEQ+++L KK GQLK
Sbjct: 27 DIDANLEKLLIFEKQVRQASDTSTNTKVLIYIADLLFRAGDFQGLNEQLVSLFKKHGQLK 86
Query: 287 QAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIKEDQGQ 466
Q++ S+VQ M Y+ D++T+I LI+TL ++ GKIYVE+ERARLT+ L++IKE+QG
Sbjct: 87 QSMTSLVQHVMTYLPGIDDLKTKINLIETLRTITDGKIYVEVERARLTQLLSQIKEEQGD 146
Query: 467 IAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKINPRVFDADT 646
I A +++ VET+G+ EK+AFIL+QVRL L R DY A ++KIN + F+ +
Sbjct: 147 IKSAQEILCNEPVETYGSFDLKEKVAFILDQVRLFLLRSDYYMASTYTKKINVKFFEKED 206
Query: 647 KKDKK 661
+ K
Sbjct: 207 VQSLK 211
>sp|Q12250|RPN5_YEAST 26S proteasome regulatory subunit RPN5 OS=Saccharomyces
cerevisiae GN=RPN5 PE=1 SV=3
Length = 445
Score = 151 bits (379), Expect = 1e-035
Identities = 78/181 (43%), Positives = 126/181 (69%), Gaps = 2/181 (1%)
Frame = +2
Query: 98 AGGNLEASIDRLLNEEKQMRLAENVAGTRKAATEILQLCFEAKDWKLLNEQILNLSKKRG 277
A + +++D+LL EK+ R A ++A +++ +I+ L W LNEQ+ LSKK G
Sbjct: 28 AQNDCNSALDQLLVLEKKTRQASDLASSKEVLAKIVDLLASRNKWDDLNEQLTLLSKKHG 87
Query: 278 QLKQAVQSMVQQAMQYI--DQTPDIETRIELIKTLNNVSAGKIYVEIERARLTRKLAKIK 451
QLK ++Q M+Q+ M+Y+ ++ D+ TRI +I+T+ V+ KI+VE+ERAR+T+ L +IK
Sbjct: 88 QLKLSIQYMIQKVMEYLKSSKSLDLNTRISVIETIRVVTENKIFVEVERARVTKDLVEIK 147
Query: 452 EDQGQIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDYVRAQILSRKINPRV 631
+++G+I EAAD++ E+ VET+G+M +EKI FILEQ+ L + + DY +A +LSRKI +
Sbjct: 148 KEEGKIDEAADILCELQVETYGSMEMSEKIQFILEQMELSILKGDYSQATVLSRKILKKT 207
Query: 632 F 634
F
Sbjct: 208 F 208
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,633,155,136
Number of Sequences: 518415
Number of Extensions: 2633155136
Number of Successful Extensions: 40810758
Number of sequences better than 0.0: 0
|
