BLASTX 7.6.2
Query= UN00718 /QuerySize=705
(704 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q56Y85|AMP2B_ARATH Methionine aminopeptidase 2B OS=Arabidopsi... 315 2e-085
sp|Q9FV49|AMP2A_ARATH Methionine aminopeptidase 2A OS=Arabidopsi... 268 2e-071
sp|O08663|AMPM2_MOUSE Methionine aminopeptidase 2 OS=Mus musculu... 176 2e-043
sp|P50579|AMPM2_HUMAN Methionine aminopeptidase 2 OS=Homo sapien... 173 1e-042
sp|Q3ZC89|AMPM2_BOVIN Methionine aminopeptidase 2 OS=Bos taurus ... 171 4e-042
sp|P38062|AMPM2_RAT Methionine aminopeptidase 2 OS=Rattus norveg... 171 5e-042
sp|O60085|AMPM2_SCHPO Methionine aminopeptidase 2 OS=Schizosacch... 168 3e-041
sp|Q55C21|AMPM2_DICDI Methionine aminopeptidase 2 OS=Dictyosteli... 157 1e-037
sp|Q6XMH6|AMPM2_ENCHE Methionine aminopeptidase 2 OS=Encephalito... 62 2e-009
>sp|Q56Y85|AMP2B_ARATH Methionine aminopeptidase 2B OS=Arabidopsis thaliana
GN=MAP2B PE=2 SV=2
Length = 439
Score = 315 bits (807), Expect = 2e-085
Identities = 166/199 (83%), Positives = 179/199 (89%), Gaps = 10/199 (5%)
Frame = +3
Query: 123 MASETPEVVVAPVVVENGGA--SKGKEEQQSLESELSKKLEITEDAKEENDEEQEEGSKA 296
MASE+P+V V VVENGGA S GKEEQ LESELSKKLEI ED +EEND EEGSKA
Sbjct: 1 MASESPDVAVVAPVVENGGAESSNGKEEQ--LESELSKKLEIAEDGQEEND--GEEGSKA 56
Query: 297 ETSTTKKKKKKNKSKKKL---QQTDPPTIPVVKLFPSGDFPEGEIQQYKDDNLWRTTSEE 467
ETS TKKKKKKNKSKKK QQTDPP+IPVV+LFPSG+FPEGEIQ+YKDDNLWRTTSEE
Sbjct: 57 ETS-TKKKKKKNKSKKKKELPQQTDPPSIPVVELFPSGEFPEGEIQEYKDDNLWRTTSEE 115
Query: 468 KRDLERLQKPIYNSVRQAAEVHRQVRKYVRSVVKPGMLMTDICETLEDTVRKLISENGLK 647
KR+LER +KPIYNSVR+AAEVHRQVRKYVRS+VKPGMLMTDICETLE+TVRKLISENGL+
Sbjct: 116 KRELERFEKPIYNSVRRAAEVHRQVRKYVRSIVKPGMLMTDICETLENTVRKLISENGLQ 175
Query: 648 AGIAFPTGCSLNWVAAHWT 704
AGIAFPTGCSLNWVAAHWT
Sbjct: 176 AGIAFPTGCSLNWVAAHWT 194
>sp|Q9FV49|AMP2A_ARATH Methionine aminopeptidase 2A OS=Arabidopsis thaliana
GN=MAP2A PE=2 SV=2
Length = 441
Score = 268 bits (685), Expect = 2e-071
Identities = 138/199 (69%), Positives = 166/199 (83%), Gaps = 8/199 (4%)
Frame = +3
Query: 123 MASETPEVVVAPVVVENGGASKGKEEQQSLESELSKKLEITE--DAKEENDEEQEEGSKA 296
MA PE VA + EN A + L S+L+K L++ E + +++N++E+E+G KA
Sbjct: 1 MAIGNPE--VATMGKENTEAESSNGNESQLSSDLTKSLDLAEVKEDEKDNNQEEEDGLKA 58
Query: 297 ETSTTKKKKKKNKSKKK---LQQTDPPTIPVVKLFPSGDFPEGEIQQYKDDNLWRTTSEE 467
E S TKKKKKK+KSKKK LQQTDPP+IPV++LFPSGDFP+GEIQQY DDNLWRTTSEE
Sbjct: 59 EAS-TKKKKKKSKSKKKKSSLQQTDPPSIPVLELFPSGDFPQGEIQQYNDDNLWRTTSEE 117
Query: 468 KRDLERLQKPIYNSVRQAAEVHRQVRKYVRSVVKPGMLMTDICETLEDTVRKLISENGLK 647
KR++ERLQKPIYNS+RQAAEVHRQVRKY+RS++KPGMLM D+CETLE+TVRKLISENGL+
Sbjct: 118 KREMERLQKPIYNSLRQAAEVHRQVRKYMRSILKPGMLMIDLCETLENTVRKLISENGLQ 177
Query: 648 AGIAFPTGCSLNWVAAHWT 704
AGIAFPTGCSLN VAAHWT
Sbjct: 178 AGIAFPTGCSLNNVAAHWT 196
>sp|O08663|AMPM2_MOUSE Methionine aminopeptidase 2 OS=Mus musculus GN=Metap2
PE=1 SV=1
Length = 478
Score = 176 bits (445), Expect = 2e-043
Identities = 90/176 (51%), Positives = 121/176 (68%), Gaps = 6/176 (3%)
Frame = +3
Query: 195 EEQQSLESELSKKLEITEDAKEENDEEQEEG-SKAETSTTKKKKKKNKSKKKLQQTDPPT 371
+E +L E++K+LE ++E D++ E+G A+ +T KKKKKK K + QTDPP+
Sbjct: 58 KESGALVDEVAKQLESQALEEKERDDDDEDGDGDADGATGKKKKKKKKKRGPKVQTDPPS 117
Query: 372 IPVVKLFPSGDFPEGEIQQYKDDN-----LWRTTSEEKRDLERLQKPIYNSVRQAAEVHR 536
+P+ L+P+G FP+G+ +Y WRTTSEEK+ L++ + I+N R+AAE HR
Sbjct: 118 VPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHR 177
Query: 537 QVRKYVRSVVKPGMLMTDICETLEDTVRKLISENGLKAGIAFPTGCSLNWVAAHWT 704
QVRKYV S +KPGM M +ICE LED RKLI ENGL AG+AFPTGCSLN AAH+T
Sbjct: 178 QVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYT 233
>sp|P50579|AMPM2_HUMAN Methionine aminopeptidase 2 OS=Homo sapiens GN=METAP2
PE=1 SV=1
Length = 478
Score = 173 bits (438), Expect = 1e-042
Identities = 92/187 (49%), Positives = 123/187 (65%), Gaps = 11/187 (5%)
Frame = +3
Query: 177 GASKGKEEQQSLES-----ELSKKLEITEDAKEENDEEQEEG-SKAETSTTKKKKKKNKS 338
G S E++ ES E++++LE + +E DE+ E+G + +T KKKKKK K
Sbjct: 47 GPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKK 106
Query: 339 KKKLQQTDPPTIPVVKLFPSGDFPEGEIQQYKDDN-----LWRTTSEEKRDLERLQKPIY 503
+ QTDPP++P+ L+P+G FP+G+ +Y WRTTSEEK+ L++ + I+
Sbjct: 107 RGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIW 166
Query: 504 NSVRQAAEVHRQVRKYVRSVVKPGMLMTDICETLEDTVRKLISENGLKAGIAFPTGCSLN 683
N R+AAE HRQVRKYV S +KPGM M +ICE LED RKLI ENGL AG+AFPTGCSLN
Sbjct: 167 NDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLN 226
Query: 684 WVAAHWT 704
AAH+T
Sbjct: 227 NCAAHYT 233
>sp|Q3ZC89|AMPM2_BOVIN Methionine aminopeptidase 2 OS=Bos taurus GN=METAP2 PE=2
SV=1
Length = 477
Score = 171 bits (433), Expect = 4e-042
Identities = 89/186 (47%), Positives = 124/186 (66%), Gaps = 10/186 (5%)
Frame = +3
Query: 177 GASKGKEEQQ----SLESELSKKLEITEDAKEENDEEQEEG-SKAETSTTKKKKKKNKSK 341
GA+ G++E + E++++LE ++E D++ E+G + +T KKKKKK K +
Sbjct: 47 GAATGQQEPDKEAGASVDEVTRQLERQALEEKEKDDDDEDGDGDGDGATGKKKKKKKKKR 106
Query: 342 KKLQQTDPPTIPVVKLFPSGDFPEGEIQQYKDDN-----LWRTTSEEKRDLERLQKPIYN 506
QTDPP++P+ L+P+G FP+G+ +Y WRTTSEEK+ L++ + I+N
Sbjct: 107 GPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWN 166
Query: 507 SVRQAAEVHRQVRKYVRSVVKPGMLMTDICETLEDTVRKLISENGLKAGIAFPTGCSLNW 686
R+AAE HRQVRKYV S +KPGM M +ICE +ED RKLI ENGL AG+AFPTGCSLN
Sbjct: 167 DFREAAEAHRQVRKYVMSWIKPGMTMIEICEKMEDCSRKLIKENGLNAGLAFPTGCSLNN 226
Query: 687 VAAHWT 704
AAH+T
Sbjct: 227 CAAHYT 232
>sp|P38062|AMPM2_RAT Methionine aminopeptidase 2 OS=Rattus norvegicus GN=Metap2
PE=2 SV=2
Length = 478
Score = 171 bits (432), Expect = 5e-042
Identities = 91/186 (48%), Positives = 122/186 (65%), Gaps = 7/186 (3%)
Frame = +3
Query: 165 VENGGASKGKEEQQSLESELSKKLEITEDAKEENDEEQEEG-SKAETSTTKKKKKKNKSK 341
V G KE S++ E++K+LE ++E D++ E+G + + KKKKKK K +
Sbjct: 49 VSAGQQELDKESGTSVD-EVAKQLERQALEEKEKDDDDEDGDGDGDGAAGKKKKKKKKKR 107
Query: 342 KKLQQTDPPTIPVVKLFPSGDFPEGEIQQYKDDN-----LWRTTSEEKRDLERLQKPIYN 506
QTDPP++P+ L+P+G FP+G+ +Y WRTTSEEK+ L++ + I+N
Sbjct: 108 GPRVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWN 167
Query: 507 SVRQAAEVHRQVRKYVRSVVKPGMLMTDICETLEDTVRKLISENGLKAGIAFPTGCSLNW 686
R+AAE HRQVRKYV S +KPGM M +ICE LED RKLI ENGL AG+AFPTGCSLN
Sbjct: 168 DFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNN 227
Query: 687 VAAHWT 704
AAH+T
Sbjct: 228 CAAHYT 233
>sp|O60085|AMPM2_SCHPO Methionine aminopeptidase 2 OS=Schizosaccharomyces pombe
GN=fma2 PE=2 SV=1
Length = 426
Score = 168 bits (425), Expect = 3e-041
Identities = 85/170 (50%), Positives = 114/170 (67%), Gaps = 3/170 (1%)
Frame = +3
Query: 204 QSLESELS-KKLEITED--AKEENDEEQEEGSKAETSTTKKKKKKNKSKKKLQQTDPPTI 374
+ L+ +LS K+ ++ ED EEND +E S E KKKK K K +QT+PPT+
Sbjct: 12 KDLQEKLSLKENDVVEDDGKVEENDAAEEGASNGEKKKKKKKKSSKKKKTPQEQTNPPTV 71
Query: 375 PVVKLFPSGDFPEGEIQQYKDDNLWRTTSEEKRDLERLQKPIYNSVRQAAEVHRQVRKYV 554
+ K+F + +P GE+ Y +DNLWRTT EEKR L+R YN +R+AAEVHRQ R+Y
Sbjct: 72 GLSKIFVNKKYPVGEVCDYAEDNLWRTTDEEKRALDRQNFDQYNDLRRAAEVHRQARQYA 131
Query: 555 RSVVKPGMLMTDICETLEDTVRKLISENGLKAGIAFPTGCSLNWVAAHWT 704
+SV+KPGM M D+ T+E+T R L+ E+GLK+GI FPTG SLN AAH+T
Sbjct: 132 QSVIKPGMSMMDVVNTIENTTRALVEEDGLKSGIGFPTGVSLNHCAAHYT 181
>sp|Q55C21|AMPM2_DICDI Methionine aminopeptidase 2 OS=Dictyostelium discoideum
GN=metap2 PE=3 SV=3
Length = 436
Score = 157 bits (395), Expect = 1e-037
Identities = 87/189 (46%), Positives = 119/189 (62%), Gaps = 1/189 (0%)
Frame = +3
Query: 138 PEVVVAPVVVENGGASKGKEEQQSLESELSKKLEITEDAKEENDEEQEEGSKAETSTTKK 317
P+ V P VE S +E+ + +E AK++ + +++ A ++
Sbjct: 6 PKTEVPPKTVEEEEESDDEEDNTKV-TEGGNPTGGEGAAKKKKKKNKKKKKAAPVASAAD 64
Query: 318 KKKKNKSKKKLQQTDPPTIPVVKLFPSGDFPEGEIQQYKDDNLWRTTSEEKRDLERLQKP 497
L QT+PPTIPV K F +G +P GEIQ+Y+D N +RTTSEEKR ER+
Sbjct: 65 IIDSKPIPSGLVQTNPPTIPVSKQFSNGVYPMGEIQEYRDSNSYRTTSEEKRLEERIHAN 124
Query: 498 IYNSVRQAAEVHRQVRKYVRSVVKPGMLMTDICETLEDTVRKLISENGLKAGIAFPTGCS 677
IYN VR+AAEVHRQVRKYV+ +VKPG+ +T++ E+LE+ R LI +GLKAGIAFPTG S
Sbjct: 125 IYNDVRRAAEVHRQVRKYVQGIVKPGLGLTELVESLENASRTLIEADGLKAGIAFPTGVS 184
Query: 678 LNWVAAHWT 704
LN +AAH+T
Sbjct: 185 LNHIAAHFT 193
>sp|Q6XMH6|AMPM2_ENCHE Methionine aminopeptidase 2 OS=Encephalitozoon hellem
GN=MAP2 PE=3 SV=1
Length = 358
Score = 62 bits (150), Expect = 2e-009
Identities = 31/72 (43%), Positives = 47/72 (65%), Gaps = 1/72 (1%)
Frame = +3
Query: 489 QKPIYNSVRQAAEVHRQVRKYVRSVVKPGMLMTDICETLEDTVRKLISENGLKAGIAFPT 668
+ I R+AAE HR+VR V+S++KPGM + +I +++ED+ R L+S GI FP
Sbjct: 41 ESDILQDARRAAEAHRRVRYKVQSIIKPGMTLLEIVKSIEDSTRILLS-GERNNGIGFPA 99
Query: 669 GCSLNWVAAHWT 704
G S+N AAH++
Sbjct: 100 GMSMNSCAAHYS 111
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,154,264,487
Number of Sequences: 518415
Number of Extensions: 3154264487
Number of Successful Extensions: 47263005
Number of sequences better than 0.0: 0
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