BLASTX 7.6.2
Query= UN00732 /QuerySize=1716
(1715 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q96529|PURA_ARATH Adenylosuccinate synthetase, chloroplastic ... 906 8e-263
sp|O24396|PURA_WHEAT Adenylosuccinate synthetase, chloroplastic ... 716 1e-205
sp|O24578|PURA_MAIZE Adenylosuccinate synthetase, chloroplastic ... 705 4e-202
sp|P21900|PURA_DICDI Adenylosuccinate synthetase OS=Dictyosteliu... 490 1e-137
sp|Q02787|PURA_SCHPO Adenylosuccinate synthetase OS=Schizosaccha... 465 8e-130
sp|Q9Y0Y2|PURA_DROME Adenylosuccinate synthetase OS=Drosophila m... 448 7e-125
sp|P80210|PURA_YEAST Adenylosuccinate synthetase OS=Saccharomyce... 439 3e-122
sp|B9MLK0|PURA_ANATD Adenylosuccinate synthetase OS=Anaerocellum... 398 1e-109
sp|A4XML6|PURA_CALS8 Adenylosuccinate synthetase OS=Caldicellulo... 397 2e-109
sp|A0LWT8|PURA_ACIC1 Adenylosuccinate synthetase OS=Acidothermus... 389 5e-107
sp|Q9CE93|PURA_LACLA Adenylosuccinate synthetase OS=Lactococcus ... 385 6e-106
sp|Q02WK8|PURA_LACLS Adenylosuccinate synthetase OS=Lactococcus ... 384 1e-105
sp|A2RN80|PURA_LACLM Adenylosuccinate synthetase OS=Lactococcus ... 383 2e-105
sp|B3EAS4|PURA_GEOLS Adenylosuccinate synthetase OS=Geobacter lo... 374 2e-102
sp|A5F534|PURA_VIBC3 Adenylosuccinate synthetase OS=Vibrio chole... 366 4e-100
sp|Q9KNX8|PURA_VIBCH Adenylosuccinate synthetase OS=Vibrio chole... 366 4e-100
sp|C3LRR4|PURA_VIBCM Adenylosuccinate synthetase OS=Vibrio chole... 366 4e-100
sp|A4XPZ3|PURA_PSEMY Adenylosuccinate synthetase OS=Pseudomonas ... 358 8e-098
sp|Q2SBC8|PURA_HAHCH Adenylosuccinate synthetase OS=Hahella chej... 354 1e-096
sp|Q7VKR5|PURA_HAEDU Adenylosuccinate synthetase OS=Haemophilus ... 348 8e-095
>sp|Q96529|PURA_ARATH Adenylosuccinate synthetase, chloroplastic OS=Arabidopsis
thaliana GN=At3g57610 PE=1 SV=1
Length = 490
Score = 906 bits (2341), Expect = 8e-263
Identities = 451/490 (92%), Positives = 469/490 (95%), Gaps = 1/490 (0%)
Frame = +1
Query: 79 SLSSLSLNSKPRFAVGGPCHRRYPQLHHPRSFVSYSSKRPTVSASLSVTADSTTTEQPLQ 258
SLSSL+L+S PRFAVGGP HRRYP LHHPRSFVS S+KRP VSASLSV ADS TE L
Sbjct: 2 SLSSLTLDSNPRFAVGGPYHRRYPPLHHPRSFVSCSAKRPAVSASLSVAADSAATES-LG 60
Query: 259 RIESLSQVSGVLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHL 438
RI SLSQVSGVLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHL
Sbjct: 61 RIGSLSQVSGVLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHL 120
Query: 439 VPSGILNEDTTCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVD 618
VPSGILNEDTTCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVD
Sbjct: 121 VPSGILNEDTTCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVD 180
Query: 619 GLRESELAKSFIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKLEVLLADAAARFKG 798
GLRESELAKSFIGTTKRGIGP YSSKVIRNGIRVGDLRHMDTLPQKL++LL+DAAARF+G
Sbjct: 181 GLRESELAKSFIGTTKRGIGPAYSSKVIRNGIRVGDLRHMDTLPQKLDLLLSDAAARFQG 240
Query: 799 FKYSPEMLREEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTY 978
FKY+PEMLREEVEAYKRYA+RLEPYITDTVHF+ND+ISQK++VLVEGGQATMLDIDFGTY
Sbjct: 241 FKYTPEMLREEVEAYKRYADRLEPYITDTVHFINDSISQKKKVLVEGGQATMLDIDFGTY 300
Query: 979 PFVTSSSPSAGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQ 1158
PFVTSSSPSAGGICTGLGIAP VGDLIGVVKAYTTRVGSGPFPTENLG GGDLLRLAGQ
Sbjct: 301 PFVTSSSPSAGGICTGLGIAPSVVGDLIGVVKAYTTRVGSGPFPTENLGTGGDLLRLAGQ 360
Query: 1159 EFGTTTGRPRRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRV 1338
EFGTTTGRPRRCGWLD+VAL+FSCQINGFASLNLTKLDVLSDL EIQLGVAYK+SDGT V
Sbjct: 361 EFGTTTGRPRRCGWLDIVALKFSCQINGFASLNLTKLDVLSDLNEIQLGVAYKRSDGTPV 420
Query: 1339 DSFPGDLRLLEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGI 1518
SFPGDLRLLEEL VEYEVLPGWK DISS+RNY+DLPKAAQQYVERIEELVGVPIHYIGI
Sbjct: 421 KSFPGDLRLLEELHVEYEVLPGWKSDISSVRNYSDLPKAAQQYVERIEELVGVPIHYIGI 480
Query: 1519 GPGRDALIYK 1548
GPGRDALIYK
Sbjct: 481 GPGRDALIYK 490
>sp|O24396|PURA_WHEAT Adenylosuccinate synthetase, chloroplastic (Fragment)
OS=Triticum aestivum PE=1 SV=1
Length = 476
Score = 716 bits (1848), Expect = 1e-205
Identities = 347/451 (76%), Positives = 393/451 (87%), Gaps = 5/451 (1%)
Frame = +1
Query: 196 PTVSASLSVTADSTTTEQPLQRIESLSQVSGVLGCQWGDEGKGKLVDILAQHFDIVARCQ 375
P +++L+V AD R+ SLSQVSGVLG QWGDEGKGKLVD+LA FDIVARCQ
Sbjct: 31 PAAASALAVEADPAA-----DRVSSLSQVSGVLGSQWGDEGKGKLVDVLAPRFDIVARCQ 85
Query: 376 GGANAGHTIYNSEGKKFALHLVPSGILNEDTTCVIGNGVVVHLPGLFKEIDGLESNGVSC 555
GGANAGHTIYNSEGKKFALHLVPSGIL+E T CV+GNG V+H+PG F EIDGL+SNGVSC
Sbjct: 86 GGANAGHTIYNSEGKKFALHLVPSGILHEGTLCVVGNGAVIHVPGFFGEIDGLQSNGVSC 145
Query: 556 KGRILVSDRAHLLFDFHQEVDGLRESELAKSFIGTTKRGIGPCYSSKVIRNGIRVGDLRH 735
GRILVSDRAHLLFD HQ VDGLRE+ELA SFIGTTKRGIGPCYSSKV RNG+RV DLRH
Sbjct: 146 DGRILVSDRAHLLFDLHQTVDGLREAELANSFIGTTKRGIGPCYSSKVTRNGLRVCDLRH 205
Query: 736 MDTLPQKLEVLLADAAARFKGFKYSPEMLREEVEAYKRYAERLEPYITDTVHFMNDAISQ 915
MDT KL+VL DAAARF+GFKYS ML+EEVE YKR+AERLEP+I DTVH +N++I Q
Sbjct: 206 MDTFGDKLDVLFEDAAARFEGFKYSKGMLKEEVERYKRFAERLEPFIADTVHVLNESIRQ 265
Query: 916 KRRVLVEGGQATMLDIDFGTYPFVTSSSPSAGGICTGLGIAPRAVGDLIGVVKAYTTRVG 1095
K+++LVEGGQATMLDIDFGTYPFVTSSSPSAGGICTGLGIAPR +GDLIGVVKAYTTRVG
Sbjct: 266 KKKILVEGGQATMLDIDFGTYPFVTSSSPSAGGICTGLGIAPRVIGDLIGVVKAYTTRVG 325
Query: 1096 SGPFPTENLGPGGDLLRLAGQEFGTTTGRPRRCGWLDLVALRFSCQINGFASLNLTKLDV 1275
SGPFPTE LG GD+LR AG EFGTTTGRPRRCGWLD+VAL++ C INGF+SLNLTKLDV
Sbjct: 326 SGPFPTELLGEEGDVLRKAGMEFGTTTGRPRRCGWLDIVALKYCCDINGFSSLNLTKLDV 385
Query: 1276 LSDLEEIQLGVAYKKSDGTRVDSFPGDLRLLEELQVEYEVLPGWKFDISSIRNYADLPKA 1455
LS L EI+LGV+Y + DG ++ SFPGDL LE++QV YEVLPGW DISS+R+Y++LP+A
Sbjct: 386 LSGLPEIKLGVSYNQMDGEKLQSFPGDLDTLEQVQVNYEVLPGWDSDISSVRSYSELPQA 445
Query: 1456 AQQYVERIEELVGVPIHYIGIGPGRDALIYK 1548
A++YVERIEEL GVP+HYIG+GPGRDALIYK
Sbjct: 446 ARRYVERIEELAGVPVHYIGVGPGRDALIYK 476
>sp|O24578|PURA_MAIZE Adenylosuccinate synthetase, chloroplastic OS=Zea mays
PE=2 SV=1
Length = 484
Score = 705 bits (1817), Expect = 4e-202
Identities = 347/482 (71%), Positives = 400/482 (82%), Gaps = 4/482 (0%)
Frame = +1
Query: 103 SKPRFAVGGPCHRRYPQLHHPRSFVSYSSKRPTVSASLSVTADSTTTEQPLQRIESLSQV 282
S P A G +P +S V + R V A++S + E R+ SL+QV
Sbjct: 7 SHPAAAAAGSGKSLFPAGPAAQS-VHFPKARLPVPAAVSAATAAVHAE---DRVSSLTQV 62
Query: 283 SGVLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILNE 462
SGVLG QWGDEGKGKLVD+LA FDIVARCQGGANAGHTIYNSEGKKFALHLVPSGIL+E
Sbjct: 63 SGVLGSQWGDEGKGKLVDVLAPRFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILHE 122
Query: 463 DTTCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVDGLRESELA 642
T CV+GNG V+H+PG F EIDGLESNGV C GRILVSDRAHLLFD HQ VDGLRE+EL
Sbjct: 123 GTLCVVGNGAVIHVPGFFGEIDGLESNGVRCGGRILVSDRAHLLFDLHQAVDGLREAELE 182
Query: 643 KSFIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKLEVLLADAAARFKGFKYSPEML 822
SFIGTTKRGIGPCYSSKV RNG+RV DLRHMDT KL++L DAA+RF+GF+YS +L
Sbjct: 183 NSFIGTTKRGIGPCYSSKVTRNGLRVCDLRHMDTFGDKLDILFKDAASRFQGFQYSKSLL 242
Query: 823 REEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFVTSSSP 1002
+EEVE YK++A+RLEP+I DTVH +N++I QK+++LVEGGQATMLDIDFGTYPFVTSSSP
Sbjct: 243 KEEVERYKKFADRLEPFIADTVHVLNESIKQKKKILVEGGQATMLDIDFGTYPFVTSSSP 302
Query: 1003 SAGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFGTTTGR 1182
SAGGICTGLGIAPRA+GDLIGVVKAYT+RVGSGPFPTE G GD LR AG EFGTTTGR
Sbjct: 303 SAGGICTGLGIAPRAIGDLIGVVKAYTSRVGSGPFPTELFGEEGDRLRKAGMEFGTTTGR 362
Query: 1183 PRRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSFPGDLR 1362
PRRCGWLD+VAL+ SCQINGF+SLNLTKLDVLS L EI++GV+Y ++DG ++ SFPGDL
Sbjct: 363 PRRCGWLDIVALKHSCQINGFSSLNLTKLDVLSGLSEIKVGVSYTQTDGQKLQSFPGDLD 422
Query: 1363 LLEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPGRDALI 1542
LE++QV YEVLPGW+ DISS+R Y +LP+AA+ YVERIEELVGVP+HYIG+GPGRDALI
Sbjct: 423 TLEQVQVNYEVLPGWQSDISSVRRYDELPQAARLYVERIEELVGVPVHYIGVGPGRDALI 482
Query: 1543 YK 1548
YK
Sbjct: 483 YK 484
>sp|P21900|PURA_DICDI Adenylosuccinate synthetase OS=Dictyostelium discoideum
GN=purA PE=1 SV=1
Length = 427
Score = 490 bits (1261), Expect = 1e-137
Identities = 244/422 (57%), Positives = 305/422 (72%), Gaps = 9/422 (2%)
Frame = +1
Query: 289 VLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILNEDT 468
++G QWGDEGKGKLVDIL+Q FD+VARCQGGANAGHTI +GKK ALHL+PSGILNE
Sbjct: 5 IIGSQWGDEGKGKLVDILSQQFDVVARCQGGANAGHTIV-VDGKKIALHLIPSGILNEKA 63
Query: 469 TCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVDGLRESEL--- 639
+C++GNG+V+HLP FKE+ GL+ G++ KGR+ VSDRAHL+FD HQ +D ++E+EL
Sbjct: 64 SCILGNGMVIHLPTFFKEVQGLQDKGINYKGRLFVSDRAHLVFDLHQMIDAMKEAELSNG 123
Query: 640 -AKSFIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKLEVLLADAAARFKGFKYSPE 816
+ IGTTKRGIGPCYSSK R G+RV DL + + L+ + RF F+Y E
Sbjct: 124 TSNDSIGTTKRGIGPCYSSKASRGGLRVCDLYSPEHFRKTFTRLVENKHKRFGSFEYDVE 183
Query: 817 MLREEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFVTSS 996
E++ Y+ +AE L+P++ D+V+++N A ++VL+EG Q+TMLD+DFG YP+VTSS
Sbjct: 184 ---AELKRYQEFAEMLKPFVIDSVYYLNQAFKDGKKVLIEGAQSTMLDLDFGCYPYVTSS 240
Query: 997 SPSAGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFGTTT 1176
+ S GG CTGLGI+P V IGVVKAYTT+VGSGPFPTE GD LR AG EFGTTT
Sbjct: 241 ASSVGGACTGLGISPNKVVTQIGVVKAYTTKVGSGPFPTEQNDHVGDSLRKAGSEFGTTT 300
Query: 1177 GRPRRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSFPGD 1356
GRPRR GWLD V LR++ IN F LNLTKLDVLSD EEI++GV YK G + SFP
Sbjct: 301 GRPRRIGWLDAVVLRYTSMINDFTRLNLTKLDVLSDFEEIKIGVDYKYK-GETIKSFPAS 359
Query: 1357 LRLLEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPGRDA 1536
L L + +V YE PGWK D+S + Y LP A+ Y++RIEELVGVPI YIG+G R
Sbjct: 360 LETLAQCEVVYESFPGWKCDLSHVTEYDQLPIQAKNYIKRIEELVGVPIVYIGVGVERKN 419
Query: 1537 LI 1542
LI
Sbjct: 420 LI 421
>sp|Q02787|PURA_SCHPO Adenylosuccinate synthetase OS=Schizosaccharomyces pombe
GN=ade2 PE=2 SV=2
Length = 434
Score = 465 bits (1194), Expect = 8e-130
Identities = 225/423 (53%), Positives = 300/423 (70%), Gaps = 5/423 (1%)
Frame = +1
Query: 280 VSGVLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILN 459
++ VLG QWGDEGKGKLVDIL + D+ ARCQGG NAGHTI + G + H++PSG++N
Sbjct: 16 ITVVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIV-ANGVTYDFHILPSGLVN 74
Query: 460 EDTTCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVDGLRESEL 639
+IG+GVVV+LP F E++ LE G+ C+ RI +SDRAHL+FD+HQ D L E+EL
Sbjct: 75 PKCQNLIGSGVVVYLPAFFSELEKLEQKGLKCRDRIFISDRAHLVFDYHQRADALNEAEL 134
Query: 640 AKSFIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKLEVLLADAAARFKGFKYSPEM 819
K IGTT +GIGP YS+K R+GIRV L H + +AD R+ F+Y E
Sbjct: 135 GKQSIGTTGKGIGPAYSTKATRSGIRVHHLYHWAEFEARYRKNVADLQKRYGAFEYDVE- 193
Query: 820 LREEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFVTSSS 999
E+ YK A+RL+P++ D V FM +A+ K+R+LVEG A MLD+DFGTYPFVTSS+
Sbjct: 194 --AELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTYPFVTSSN 251
Query: 1000 PSAGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFGTTTG 1179
+ GG+CTGLG+ P+ + + IGVVKAYTTRVG+GPFPTE L GD L+ G+E G TTG
Sbjct: 252 TTVGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTG 311
Query: 1180 RPRRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSFPGDL 1359
R RRCGWLDLV +++S ING+ SLNLTKLD+L L+EI++ VAY +G R+++FP DL
Sbjct: 312 RKRRCGWLDLVVVKYSTMINGYTSLNLTKLDILDALDEIKVAVAY-IINGKRIETFPADL 370
Query: 1360 RLLEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPGRDAL 1539
LEE ++ YE PGWK + I ++ +P+ A++Y+E IE+ VGVPI +IG+GPGRD +
Sbjct: 371 DSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIEFIEKFVGVPITFIGVGPGRDEM 430
Query: 1540 IYK 1548
+ K
Sbjct: 431 LVK 433
>sp|Q9Y0Y2|PURA_DROME Adenylosuccinate synthetase OS=Drosophila melanogaster
GN=CG17273 PE=1 SV=1
Length = 447
Score = 448 bits (1151), Expect = 7e-125
Identities = 218/425 (51%), Positives = 297/425 (69%), Gaps = 6/425 (1%)
Frame = +1
Query: 274 SQVSGVLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGI 453
S+V VLG QWGDEGKGK+VD+LA DIV RCQGG NAGHT+ + G +F HL+PSG+
Sbjct: 24 SKVDVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVV-ANGTEFDFHLLPSGV 82
Query: 454 LNEDTTCVIGNGVVVHLPGLFKEIDGLESNGVS-CKGRILVSDRAHLLFDFHQEVDGLRE 630
+NE VIGNGVV+HLP LF E+ E+ G+ + R+++SDRAHL+FDFHQ VDG++E
Sbjct: 83 VNEKCVSVIGNGVVIHLPSLFDEVLKNEAKGLQHLENRLIISDRAHLVFDFHQHVDGMQE 142
Query: 631 SELAKSFIGTTKRGIGPCYSSKVIRNGIRVGD-LRHMDTLPQKLEVLLADAAARFKGFKY 807
+E +GTTK+GIGP YSSK RNGIRVG+ L + +K + ++A F
Sbjct: 143 AEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLGDFNLFSEKFKSIVATHVRLFPSINV 202
Query: 808 SPEMLREEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFV 987
E E+ YK YA+++ PY+ DT+ F++ A+ + +LVEG A MLDIDFGTYP+V
Sbjct: 203 DVE---AELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYV 259
Query: 988 TSSSPSAGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFG 1167
TSS+ S GG+ TGLG+ P+ +G++IGVVKAYTTRVG GPFPTE L GDLL+ G E G
Sbjct: 260 TSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVG 319
Query: 1168 TTTGRPRRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSF 1347
TT R RRCGWLD+ L+++ +NG+ + LTKLD+L L EI++ VAYKK +G ++D F
Sbjct: 320 VTTKRKRRCGWLDIPLLKYTSLVNGYTCICLTKLDILDTLPEIKVAVAYKKPNGEKLDHF 379
Query: 1348 PGDLRLLEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPG 1527
PG + L ++VEY VLPGW+ +RN+ +LP+ AQ YV +E + VP+ ++G+G G
Sbjct: 380 PGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVRLLESELSVPVRWVGVGKG 439
Query: 1528 RDALI 1542
R+++I
Sbjct: 440 RESII 444
>sp|P80210|PURA_YEAST Adenylosuccinate synthetase OS=Saccharomyces cerevisiae
GN=ADE12 PE=1 SV=3
Length = 433
Score = 439 bits (1129), Expect = 3e-122
Identities = 221/434 (50%), Positives = 305/434 (70%), Gaps = 16/434 (3%)
Frame = +1
Query: 280 VSGVLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILN 459
V+ VLG QWGDEGKGKLVD+L +DIVARC GG NAGHTI +G K+ H++PSG++N
Sbjct: 2 VNVVLGSQWGDEGKGKLVDLLVGKYDIVARCAGGNNAGHTIV-VDGVKYDFHMLPSGLVN 60
Query: 460 EDTTCVIGNGVVVHLPGLFKEIDGLESNGV-SCKGRILVSDRAHLLFDFHQEVDGLRESE 636
+ ++GNGVV+H+P FKE++ LE+ G+ + + R+ VS RAHL+FDFHQ D LRE E
Sbjct: 61 PNCQNLLGNGVVIHVPSFFKELETLEAKGLKNARSRLFVSSRAHLVFDFHQVTDKLRELE 120
Query: 637 LA-----KSFIGTTKRGIGPCYSSKVIRNGIRVGDLRH-----MDTLPQKLEVLLADAAA 786
L+ IGTT +GIGP YS+K R+G+RV L + + + + LL
Sbjct: 121 LSGRSKDGKNIGTTGKGIGPTYSTKASRSGLRVHHLVNDQPGAWEEFVARYKRLLETRRQ 180
Query: 787 RFKGFKYSPEMLREEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDID 966
R+ F+Y E ++ YK+ E+L+P++ D+V FM++AI K+++LVEG A MLDID
Sbjct: 181 RYGDFEYDFE---AKLAEYKKLREQLKPFVVDSVVFMHNAIEAKKKILVEGANALMLDID 237
Query: 967 FGTYPFVTSSSPSAGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLR 1146
FGTYP+VTSS+ GG+ TGLGI PR + ++ GVVKAYTTRVG GPFPTE L G+ L+
Sbjct: 238 FGTYPYVTSSNTGIGGVLTGLGIPPRTIDEIYGVVKAYTTRVGEGPFPTEQLNENGEKLQ 297
Query: 1147 LAGQEFGTTTGRPRRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSD 1326
G EFG TTGR RRCGWLDLV L++S ING+ SLN+TKLDVL +EI +G++Y
Sbjct: 298 TIGAEFGVTTGRKRRCGWLDLVVLKYSTLINGYTSLNITKLDVLDTFKEIPVGISY-SIQ 356
Query: 1327 GTRVDSFPGDLRLLEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIH 1506
G ++D FP DL +L +++VEY+VLPGW DI+ I Y DLP+ A++Y++ IE+ VGVP+
Sbjct: 357 GKKLDLFPEDLNILGKVEVEYKVLPGWDQDITKITKYEDLPENAKKYLKYIEDFVGVPVE 416
Query: 1507 YIGIGPGRDALIYK 1548
++G GP R+++++K
Sbjct: 417 WVGTGPARESMLHK 430
>sp|B9MLK0|PURA_ANATD Adenylosuccinate synthetase OS=Anaerocellum thermophilum
(strain DSM 6725 / Z-1320) GN=purA PE=3 SV=1
Length = 426
Score = 398 bits (1020), Expect = 1e-109
Identities = 205/426 (48%), Positives = 282/426 (66%), Gaps = 5/426 (1%)
Frame = +1
Query: 277 QVSGVLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGIL 456
Q+ ++G QWGDEGKGK+VD LA+ D+V R QGG NAGHT+ + GK F LHL+PSGIL
Sbjct: 3 QIRAIVGTQWGDEGKGKIVDFLAKEADVVVRAQGGNNAGHTV-EAFGKVFKLHLIPSGIL 61
Query: 457 NEDTTCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVDGLRESE 636
+D +IGNGVV+ L +EI+ LE G+S + + +SDRAHL+ +H+ +D +E
Sbjct: 62 YKDKLNIIGNGVVIDPESLIQEIESLEKEGISTE-NLKISDRAHLVMPYHKILDEEQERL 120
Query: 637 LAKSFIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKLEVLLADAAARFKG-FKYSP 813
+ +GTTKRGIGP Y+ K R +RV D+ + QKL + + +P
Sbjct: 121 RGEESLGTTKRGIGPAYTDKTERTNLRVCDMLDEEEFVQKLRTVYERKNQILTHVYHKTP 180
Query: 814 EMLREEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFVTS 993
E +E + +Y E L+PYITDT+ +ND+I ++VL+EG QATMLD+D+GTYP+VTS
Sbjct: 181 MKFGELLEQFMKYGEILKPYITDTIKLLNDSIKAGKKVLLEGAQATMLDLDYGTYPYVTS 240
Query: 994 SSPSAGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFGTT 1173
S P+ GG C G GIAP+ + ++IGVVKAYTTRVG GPFPTE L G+ +R G+E+GTT
Sbjct: 241 SHPTVGGFCIGAGIAPKYIQEVIGVVKAYTTRVGKGPFPTELLDEIGNSIREKGREYGTT 300
Query: 1174 TGRPRRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSFPG 1353
TGRPRRCGWLDLV +R++ ING + LTKLD LS L +I++ V Y K +G +D FP
Sbjct: 301 TGRPRRCGWLDLVVVRYAVLINGIDKIALTKLDTLSGLPKIKVCVGY-KYEGKVLDLFPA 359
Query: 1354 DLRLLEELQVEYEVLPGW-KFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPGR 1530
LR+ E + YE GW + +I + + Y LPK+A++Y+E IE+ G + IG GP R
Sbjct: 360 SLRVARECEPVYEEFEGWSEEEIKAAKEYEALPKSAKRYIEFIEKETGAKVFLIGTGPAR 419
Query: 1531 DALIYK 1548
+ +I K
Sbjct: 420 EDIIIK 425
>sp|A4XML6|PURA_CALS8 Adenylosuccinate synthetase OS=Caldicellulosiruptor
saccharolyticus (strain ATCC 43494 / DSM 8903) GN=purA PE=3 SV=1
Length = 427
Score = 397 bits (1019), Expect = 2e-109
Identities = 201/427 (47%), Positives = 284/427 (66%), Gaps = 5/427 (1%)
Frame = +1
Query: 274 SQVSGVLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGI 453
SQ+ ++G QWGDEGKGK+VD LA+ D+V R QGG+NAGHT+ + GK F LHL+PSGI
Sbjct: 2 SQIRAIVGTQWGDEGKGKIVDFLAKEADVVVRAQGGSNAGHTV-EAFGKIFKLHLIPSGI 60
Query: 454 LNEDTTCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVDGLRES 633
L +D +IGNGVV+ L +EI+ L+ G+S + + +SDRAHL+ +H+ +D +E
Sbjct: 61 LYKDKINIIGNGVVIDPESLIEEIESLQKEGISTE-NLRISDRAHLVMPYHKILDEEQEK 119
Query: 634 ELAKSFIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKLEVLL-ADAAARFKGFKYS 810
+ + +GTTKRGIGP Y+ K R +RV D+ D KL ++ + + +
Sbjct: 120 QRGEESLGTTKRGIGPAYTDKTERTNLRVCDMLDEDEFVHKLRIVYERKNRILTEVYHKT 179
Query: 811 PEMLREEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFVT 990
P E +E + +Y E L PYITDT+ +NDAI + +++L+EG QATMLD+D+GTYP+VT
Sbjct: 180 PMKFGELLEQFMKYGEILRPYITDTIKLLNDAIKEGKKILLEGAQATMLDLDYGTYPYVT 239
Query: 991 SSSPSAGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFGT 1170
SS P+ GG C G GIAP+ + ++IGVVK+YTTRVG GPFPTE L GD +R G+E+GT
Sbjct: 240 SSHPTVGGFCIGAGIAPKHIQEVIGVVKSYTTRVGKGPFPTELLDRVGDSIRERGKEYGT 299
Query: 1171 TTGRPRRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSFP 1350
TTGRPRRCGWLDLV +R++ ING + LTKLD LS+L ++++ V Y+ + G +D FP
Sbjct: 300 TTGRPRRCGWLDLVVVRYAVLINGIDKIALTKLDTLSNLPKVKVCVGYRHA-GKILDLFP 358
Query: 1351 GDLRLLEELQVEYEVLPGW-KFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPG 1527
L++ E + YE GW + +I + Y LPK A++Y+E IE+ G + IG G
Sbjct: 359 ASLKVAMECEPIYEEFDGWSEEEIKKAKEYDQLPKNAKKYIEFIEKETGAKVFLIGTGAS 418
Query: 1528 RDALIYK 1548
R+ +I K
Sbjct: 419 REDIIIK 425
>sp|A0LWT8|PURA_ACIC1 Adenylosuccinate synthetase OS=Acidothermus cellulolyticus
(strain ATCC 43068 / 11B) GN=purA PE=3 SV=1
Length = 428
Score = 389 bits (997), Expect = 5e-107
Identities = 208/422 (49%), Positives = 268/422 (63%), Gaps = 9/422 (2%)
Frame = +1
Query: 289 VLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILNEDT 468
+LG QWGDEGKGK D+LA+ D R GG NAGHTI +G+ +A+HL+PSG+L
Sbjct: 6 LLGAQWGDEGKGKATDLLAERIDYCVRFNGGNNAGHTIV-IDGETYAMHLLPSGVLTPGV 64
Query: 469 TCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVDGLRESELAKS 648
VIGNGVV+ L LF EID L + G+ R++VS AH++ +H+ +D + E L K+
Sbjct: 65 VPVIGNGVVIDLGVLFDEIDLLTARGID-TSRLVVSANAHVITAYHRVIDKVTERFLGKA 123
Query: 649 FIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKLEVLLAD----AAARFKGFKYSPE 816
IGTT RGIGP Y+ K+ R G+RV DL L QK+E L + P
Sbjct: 124 RIGTTGRGIGPAYADKMSRVGVRVQDLFDEKILRQKIEGALDQKNQLLVKVYNRRAIDPT 183
Query: 817 MLREEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFVTSS 996
+ +E+ YA+RL P + DT +NDA+ + VL+E GQ T+LD+D GTYPFVTSS
Sbjct: 184 AVADELLG---YADRLRPMVADTAALLNDALDHHKTVLLEAGQGTLLDVDHGTYPFVTSS 240
Query: 997 SPSAGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFGTTT 1176
+ +AGG CTG GI P + +I V KAYTTRVGSGPFPTE G+ LR G EFG TT
Sbjct: 241 NATAGGACTGSGIGPTRIDRVIAVAKAYTTRVGSGPFPTELHDGEGEKLRRIGAEFGVTT 300
Query: 1177 GRPRRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSFPGD 1356
GRPRRCGW D VA+R++ +ING + LTKLDVLS E I + VAY+ DG V+ P
Sbjct: 301 GRPRRCGWYDAVAVRYAMRINGVTDVVLTKLDVLSHFERIPVCVAYRLPDGRTVEEMPMT 360
Query: 1357 LRLLEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPGRDA 1536
L ++ YE LPGW+ D+S+ R+ DLPK AQ+YVE ++EL GVP IG+GPGRD
Sbjct: 361 QTELHHVEPVYEELPGWQEDLSAARSLEDLPKNAQRYVEFLQELAGVPFSVIGVGPGRDQ 420
Query: 1537 LI 1542
I
Sbjct: 421 TI 422
>sp|Q9CE93|PURA_LACLA Adenylosuccinate synthetase OS=Lactococcus lactis subsp.
lactis GN=purA PE=3 SV=1
Length = 430
Score = 385 bits (988), Expect = 6e-106
Identities = 198/416 (47%), Positives = 268/416 (64%), Gaps = 3/416 (0%)
Frame = +1
Query: 289 VLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILNEDT 468
V+G QWGDEGKGK+ D L+ + +++AR QGG NAGHTI +GKKF LHL+PSGI +
Sbjct: 6 VVGTQWGDEGKGKITDFLSSNAEVIARYQGGDNAGHTIV-IDGKKFKLHLIPSGIFFPEK 64
Query: 469 TCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVDGLRESELAKS 648
VIGNGVVV+ L +EI L NGVS + + +SDRAH++ +H+++D L+E
Sbjct: 65 ISVIGNGVVVNPKSLIEEIAYLAENGVSAES-LRISDRAHVILPYHKKLDFLQEEAKGDK 123
Query: 649 FIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKLEVLLADAAARF-KGFKYSPEMLR 825
IGTT +GIGP Y K R GIRV DL + ++L L F K + P
Sbjct: 124 KIGTTIKGIGPAYMDKAARVGIRVADLLDKEIFEERLRTNLEAKNREFVKMYDSEPIEFE 183
Query: 826 EEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFVTSSSPS 1005
E E Y Y ++L+ Y+TDT +NDA+ +RVL EG Q MLDID GTYPFVTSS+P
Sbjct: 184 EIFEEYYEYGQQLKKYVTDTSVILNDALDAGKRVLFEGAQGVMLDIDQGTYPFVTSSNPV 243
Query: 1006 AGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFGTTTGRP 1185
AGG+ G G+ P + ++GV KAYT+RVG GPFPTE G +R G E+GTTTGRP
Sbjct: 244 AGGVTIGSGVGPSKISKVVGVCKAYTSRVGDGPFPTELFDEVGHQIREVGHEYGTTTGRP 303
Query: 1186 RRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSFPGDLRL 1365
RR GW D V +R + +++G +L+L +DVLS LE +++ VAY++S+G ++ +P L+
Sbjct: 304 RRVGWFDSVVMRHAKRVSGLTNLSLNSIDVLSGLETVKICVAYERSNGEQITHYPASLKE 363
Query: 1366 LEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPGRD 1533
L + + YE LPGW DI+S R +LP+AA+ YV R+ ELVGV I +GPGR+
Sbjct: 364 LADCKPIYEELPGWSEDITSCRTLEELPEAARNYVRRVGELVGVRISTFSVGPGRE 419
>sp|Q02WK8|PURA_LACLS Adenylosuccinate synthetase OS=Lactococcus lactis subsp.
cremoris (strain SK11) GN=purA PE=3 SV=1
Length = 430
Score = 384 bits (985), Expect = 1e-105
Identities = 197/416 (47%), Positives = 267/416 (64%), Gaps = 3/416 (0%)
Frame = +1
Query: 289 VLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILNEDT 468
V+G QWGDEGKGK+ D L+ + +++AR QGG NAGHTI +GKKF LHL+PSGI +
Sbjct: 6 VVGTQWGDEGKGKITDFLSSNAEVIARYQGGDNAGHTIV-IDGKKFKLHLIPSGIFFPEK 64
Query: 469 TCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVDGLRESELAKS 648
VIGNGVVV+ L +EI L NGVS + +SDRAH++ +H+++D L+E
Sbjct: 65 ISVIGNGVVVNPKSLIEEIAYLAENGVSANS-LRISDRAHVILPYHKKLDFLQEEAKGDK 123
Query: 649 FIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKLEVLLADAAARF-KGFKYSPEMLR 825
IGTT +GIGP Y K R GIR+ DL + ++L L F K + P
Sbjct: 124 KIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERLRTNLEVKNREFVKMYDSEPLEFE 183
Query: 826 EEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFVTSSSPS 1005
E E Y Y ++L+ Y+TDT +NDA+ +RVL EG Q MLDID GTYPFVTSS+P
Sbjct: 184 EIFEEYYEYGQQLKKYVTDTSVILNDALDAGKRVLFEGAQGVMLDIDQGTYPFVTSSNPV 243
Query: 1006 AGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFGTTTGRP 1185
AGG+ G G+ P + ++GV KAYT+RVG GPFPTE G +R G E+GTTTGRP
Sbjct: 244 AGGVTIGSGVGPSKISKVVGVCKAYTSRVGDGPFPTELFDEVGHQIREVGHEYGTTTGRP 303
Query: 1186 RRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSFPGDLRL 1365
RR GW D V +R + +++G +L+L +DVLS LE +++ VAY++S+G ++ +P L+
Sbjct: 304 RRVGWFDSVVMRHAKRVSGLTNLSLNSIDVLSGLETVKICVAYERSNGEQITHYPASLKE 363
Query: 1366 LEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPGRD 1533
L + + YE LPGW DI+S R +LP+AA+ YV R+ ELVGV I +GPGR+
Sbjct: 364 LADCKPIYEELPGWSEDITSCRTLEELPEAARNYVRRVGELVGVRISTFSVGPGRE 419
>sp|A2RN80|PURA_LACLM Adenylosuccinate synthetase OS=Lactococcus lactis subsp.
cremoris (strain MG1363) GN=purA PE=3 SV=1
Length = 430
Score = 383 bits (983), Expect = 2e-105
Identities = 196/416 (47%), Positives = 267/416 (64%), Gaps = 3/416 (0%)
Frame = +1
Query: 289 VLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILNEDT 468
V+G QWGDEGKGK+ D L+ + +++AR QGG NAGHTI +GKKF LHL+PSGI +
Sbjct: 6 VVGTQWGDEGKGKITDFLSSNAEVIARYQGGDNAGHTIV-IDGKKFKLHLIPSGIFFPEK 64
Query: 469 TCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVDGLRESELAKS 648
VIGNGVVV+ L +EI L NGVS + +SDRAH++ +H+++D L+E
Sbjct: 65 ISVIGNGVVVNPKSLIEEIAYLAENGVSANS-LRISDRAHVILPYHKKLDFLQEEAKGDK 123
Query: 649 FIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKLEVLLADAAARF-KGFKYSPEMLR 825
IGTT +GIGP Y K R GIR+ DL + ++L L F K + P
Sbjct: 124 KIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERLRTNLEVKNREFVKMYDSEPLEFE 183
Query: 826 EEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFVTSSSPS 1005
E E Y Y ++L+ Y+TDT +NDA+ +RVL EG Q MLDID GTYPFVTSS+P
Sbjct: 184 EIFEEYYEYGQQLKKYVTDTSVILNDALDAGKRVLFEGAQGVMLDIDQGTYPFVTSSNPV 243
Query: 1006 AGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFGTTTGRP 1185
AGG+ G G+ P + ++GV KAYT+RVG GPFPTE G +R G E+GTTTGRP
Sbjct: 244 AGGVTIGSGVGPSKISKVVGVCKAYTSRVGDGPFPTELFDEVGHQIREVGHEYGTTTGRP 303
Query: 1186 RRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSFPGDLRL 1365
RR GW D V +R + +++G +L+L +DVLS LE +++ VAY++S+G ++ +P L+
Sbjct: 304 RRVGWFDSVVMRHAKRVSGLTNLSLNSIDVLSGLETVKICVAYERSNGEQITHYPASLKE 363
Query: 1366 LEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPGRD 1533
L + + YE LPGW DI+S R ++P+AA+ YV R+ ELVGV I +GPGR+
Sbjct: 364 LADCKPIYEELPGWSEDITSCRTLEEIPEAARNYVRRVGELVGVRISTFSVGPGRE 419
>sp|B3EAS4|PURA_GEOLS Adenylosuccinate synthetase OS=Geobacter lovleyi (strain
ATCC BAA-1151 / DSM 17278 / SZ) GN=purA PE=3 SV=1
Length = 430
Score = 374 bits (958), Expect = 2e-102
Identities = 189/416 (45%), Positives = 265/416 (63%), Gaps = 3/416 (0%)
Frame = +1
Query: 289 VLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILNEDT 468
V+G QWGDEGKGK+VDI ++ D + R QGG NAGHT+ E +K LHL+PSG+L+
Sbjct: 6 VVGAQWGDEGKGKVVDIYTEYADEIVRYQGGNNAGHTLVVGE-EKVVLHLIPSGVLHAGK 64
Query: 469 TCVIGNGVVVHLPGLFKEIDGLESNG-VSCKGRILVSDRAHLLFDFHQEVDGLRESELAK 645
CVIGNGVV+ E++ L++ G + +L+S+ H++ +H+ +D RE++
Sbjct: 65 RCVIGNGVVLDPEVFIMEVNRLKAAGRLEDDSTLLLSESLHIIMPYHKAIDIAREAKSGD 124
Query: 646 SFIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKLEVLLADAAARFKGFKYSPEMLR 825
IGTT RGIGPCY K+ R GIR+ DL +KL L + A + P
Sbjct: 125 KKIGTTGRGIGPCYEDKIGRRGIRLMDLIDPVAFSRKLRENLEEKNAILERLGEEPLGYN 184
Query: 826 EEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFVTSSSPS 1005
E Y+ +AE L+ Y+ DT ++ +++ +++L EG Q T+LD+D GTYPFVTSSS
Sbjct: 185 EIYRTYQDFAEILKKYMADTSLVLSKSVAAGKKLLFEGAQGTLLDVDHGTYPFVTSSSTC 244
Query: 1006 AGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFGTTTGRP 1185
AGG TG G++PR + +++G+ KAY TRVGSGPFPTE L G+ LR G EFG TTGRP
Sbjct: 245 AGGAATGTGVSPREIHEVVGISKAYVTRVGSGPFPTELLDETGEKLRQVGGEFGATTGRP 304
Query: 1186 RRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSFPGDLRL 1365
RRCGW D + +R++ +ING + LTKLDVLSD E I++ Y + +G +++ P L
Sbjct: 305 RRCGWFDAMVIRYAVRINGLTGIALTKLDVLSDFETIKVCTGY-RFEGQELETLPAKLET 363
Query: 1366 LEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPGRD 1533
E + YE LPGWK DI+ +R+Y LP+ A++YV R+EEL G PI + +GP RD
Sbjct: 364 FENCEPVYEELPGWKVDITGVRSYDQLPENAKKYVRRLEELAGCPIVMVSVGPRRD 419
>sp|A5F534|PURA_VIBC3 Adenylosuccinate synthetase OS=Vibrio cholerae serotype O1
(strain ATCC 39541 / Ogawa 395 / O395) GN=purA PE=3 SV=1
Length = 432
Score = 366 bits (938), Expect = 4e-100
Identities = 191/421 (45%), Positives = 255/421 (60%), Gaps = 2/421 (0%)
Frame = +1
Query: 289 VLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILNEDT 468
VLG QWGDEGKGK+VD+L + V R QGG NAGHT+ +G+K LHL+PSGIL +
Sbjct: 7 VLGTQWGDEGKGKIVDLLTEDAKYVVRYQGGHNAGHTLV-IDGQKTVLHLIPSGILRNNV 65
Query: 469 TCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVDGLRESELAKS 648
C+IGNGVV+ L KE+ GLE GV + R+ +S+ L+ +H +D RE+ K
Sbjct: 66 KCIIGNGVVLSPEALIKEMSGLEERGVPVRERLFISEACPLILPYHVALDQAREAARGKK 125
Query: 649 FIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKLEVLLADAAARFKGF-KYSPEMLR 825
IGTT RGIGP Y KV R G+RVGDL M + +KL+ ++A + + F K P
Sbjct: 126 AIGTTGRGIGPAYEDKVARRGLRVGDLFDMASFAEKLQEVMAFHNFQLEHFYKVEPVSYE 185
Query: 826 EEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFVTSSSPS 1005
+E K YAE L + D + ++ A + +++ EG Q T+LDID GTYP+VTSS+ +
Sbjct: 186 AVLEQAKGYAELLTSMVIDVTNELDAARKRGDKIMFEGAQGTLLDIDHGTYPYVTSSNTT 245
Query: 1006 AGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFGTTTGRP 1185
AGG+ G G PR +G ++G+ KAY TRVG+GPFPTE GD L G EFG TTGR
Sbjct: 246 AGGVAAGSGFGPRHLGYILGIAKAYCTRVGAGPFPTELFDEVGDHLGTKGHEFGATTGRK 305
Query: 1186 RRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSFPGDLRL 1365
RRCGW D VA+R + QIN LTKLDVL L+EI++ Y+ DG+ + P
Sbjct: 306 RRCGWFDAVAMRRAIQINSVTGFCLTKLDVLDGLKEIKICTGYQMPDGSIAEVSPMAADA 365
Query: 1366 LEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPGRDALIY 1545
E + +E +PGW + A+LP+ A Y++RIEEL GVP+ I GP R+ I
Sbjct: 366 FENVTPIFETMPGWSETTFGAKTLAELPQTALDYIKRIEELTGVPVDIISTGPDRNETII 425
Query: 1546 K 1548
K
Sbjct: 426 K 426
>sp|Q9KNX8|PURA_VIBCH Adenylosuccinate synthetase OS=Vibrio cholerae GN=purA
PE=3 SV=3
Length = 432
Score = 366 bits (938), Expect = 4e-100
Identities = 191/421 (45%), Positives = 255/421 (60%), Gaps = 2/421 (0%)
Frame = +1
Query: 289 VLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILNEDT 468
VLG QWGDEGKGK+VD+L + V R QGG NAGHT+ +G+K LHL+PSGIL +
Sbjct: 7 VLGTQWGDEGKGKIVDLLTEDAKYVVRYQGGHNAGHTLV-IDGQKTVLHLIPSGILRNNV 65
Query: 469 TCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVDGLRESELAKS 648
C+IGNGVV+ L KE+ GLE GV + R+ +S+ L+ +H +D RE+ K
Sbjct: 66 KCIIGNGVVLSPEALIKEMSGLEDRGVPVRERLFISEACPLILPYHVALDQAREAARGKK 125
Query: 649 FIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKLEVLLADAAARFKGF-KYSPEMLR 825
IGTT RGIGP Y KV R G+RVGDL M + +KL+ ++A + + F K P
Sbjct: 126 AIGTTGRGIGPAYEDKVARRGLRVGDLFDMASFAEKLQEVMAFHNFQLEHFYKVEPVSYE 185
Query: 826 EEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFVTSSSPS 1005
+E K YAE L + D + ++ A + +++ EG Q T+LDID GTYP+VTSS+ +
Sbjct: 186 AVLEQAKGYAELLTSMVIDVTNELDAARKRGDKIMFEGAQGTLLDIDHGTYPYVTSSNTT 245
Query: 1006 AGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFGTTTGRP 1185
AGG+ G G PR +G ++G+ KAY TRVG+GPFPTE GD L G EFG TTGR
Sbjct: 246 AGGVAAGSGFGPRHLGYILGIAKAYCTRVGAGPFPTELFDEVGDHLGTKGHEFGATTGRK 305
Query: 1186 RRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSFPGDLRL 1365
RRCGW D VA+R + QIN LTKLDVL L+EI++ Y+ DG+ + P
Sbjct: 306 RRCGWFDAVAMRRAIQINSVTGFCLTKLDVLDGLKEIKICTGYQMPDGSIAEVSPMAADA 365
Query: 1366 LEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPGRDALIY 1545
E + +E +PGW + A+LP+ A Y++RIEEL GVP+ I GP R+ I
Sbjct: 366 FENVTPIFETMPGWSETTFGAKTLAELPQTALDYIKRIEELTGVPVDIISTGPDRNETII 425
Query: 1546 K 1548
K
Sbjct: 426 K 426
>sp|C3LRR4|PURA_VIBCM Adenylosuccinate synthetase OS=Vibrio cholerae serotype O1
(strain M66-2) GN=purA PE=3 SV=1
Length = 432
Score = 366 bits (938), Expect = 4e-100
Identities = 191/421 (45%), Positives = 255/421 (60%), Gaps = 2/421 (0%)
Frame = +1
Query: 289 VLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILNEDT 468
VLG QWGDEGKGK+VD+L + V R QGG NAGHT+ +G+K LHL+PSGIL +
Sbjct: 7 VLGTQWGDEGKGKIVDLLTEDAKYVVRYQGGHNAGHTLV-IDGQKTVLHLIPSGILRNNV 65
Query: 469 TCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVDGLRESELAKS 648
C+IGNGVV+ L KE+ GLE GV + R+ +S+ L+ +H +D RE+ K
Sbjct: 66 KCIIGNGVVLSPEALIKEMSGLEDRGVPVRERLFISEACPLILPYHVALDQAREAARGKK 125
Query: 649 FIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKLEVLLADAAARFKGF-KYSPEMLR 825
IGTT RGIGP Y KV R G+RVGDL M + +KL+ ++A + + F K P
Sbjct: 126 AIGTTGRGIGPAYEDKVARRGLRVGDLFDMASFAEKLQEVMAFHNFQLEHFYKVEPVSYE 185
Query: 826 EEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFVTSSSPS 1005
+E K YAE L + D + ++ A + +++ EG Q T+LDID GTYP+VTSS+ +
Sbjct: 186 AVLEQAKGYAELLTSMVIDVTNELDAARKRGDKIMFEGAQGTLLDIDHGTYPYVTSSNTT 245
Query: 1006 AGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFGTTTGRP 1185
AGG+ G G PR +G ++G+ KAY TRVG+GPFPTE GD L G EFG TTGR
Sbjct: 246 AGGVAAGSGFGPRHLGYILGIAKAYCTRVGAGPFPTELFDEVGDHLGTKGHEFGATTGRK 305
Query: 1186 RRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSFPGDLRL 1365
RRCGW D VA+R + QIN LTKLDVL L+EI++ Y+ DG+ + P
Sbjct: 306 RRCGWFDAVAMRRAIQINSVTGFCLTKLDVLDGLKEIKICTGYQMPDGSIAEVSPMAADA 365
Query: 1366 LEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPGRDALIY 1545
E + +E +PGW + A+LP+ A Y++RIEEL GVP+ I GP R+ I
Sbjct: 366 FENVTPIFETMPGWSETTFGAKTLAELPQTALDYIKRIEELTGVPVDIISTGPDRNETII 425
Query: 1546 K 1548
K
Sbjct: 426 K 426
>sp|A4XPZ3|PURA_PSEMY Adenylosuccinate synthetase OS=Pseudomonas mendocina
(strain ymp) GN=purA PE=3 SV=1
Length = 431
Score = 358 bits (918), Expect = 8e-098
Identities = 193/419 (46%), Positives = 249/419 (59%), Gaps = 2/419 (0%)
Frame = +1
Query: 289 VLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILNEDT 468
VLG QWGDEGKGK+VD+L + V R QGG NAGHT+ +G+K LHL+PSGIL E
Sbjct: 7 VLGTQWGDEGKGKIVDLLTEQAAAVVRYQGGHNAGHTLV-IDGEKTVLHLIPSGILREGV 65
Query: 469 TCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVDGLRESELAKS 648
C+IGNGVVV L +EI LE GV + R+ +S L+ +H +D RE +
Sbjct: 66 ECLIGNGVVVAPDALLREITKLEEKGVPVRQRLRISPACPLILSYHVALDQAREKARGDA 125
Query: 649 FIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKLEVLLADAAARFKGFKYSPEM-LR 825
IGTT RGIGP Y KV R G+RVGDL H + KL LL + F P + +
Sbjct: 126 KIGTTGRGIGPAYEDKVARRGLRVGDLFHRERFAAKLGELLDYHNFQLVNFYKEPAIDFQ 185
Query: 826 EEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFVTSSSPS 1005
+ ++ YAE L+P + D ++D + + ++ EG Q ++LDID GTYP+VTSS+ +
Sbjct: 186 KTLDECMEYAELLKPMMADVTAVLHDLRREGKDIMFEGAQGSLLDIDHGTYPYVTSSNTT 245
Query: 1006 AGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFGTTTGRP 1185
AGGI TG G P + ++G+ KAYTTRVGSGPFPTE G L G EFG TTGR
Sbjct: 246 AGGIATGSGFGPLYLNYILGITKAYTTRVGSGPFPTELFDDVGAFLAKRGHEFGATTGRA 305
Query: 1186 RRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSFPGDLRL 1365
RRCGW D V LR + +IN + L LTKLDVL LE I++ YK ++G + P D
Sbjct: 306 RRCGWFDAVILRRAIEINSISGLCLTKLDVLDGLETIRICTGYKDANGQVLVDAPTDADS 365
Query: 1366 LEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPGRDALI 1542
LQ YE +PGW + DLP AA+ Y++R+EELVG PI I GP R+ I
Sbjct: 366 YLGLQPVYEEMPGWSESTLGAKTLEDLPAAARAYIKRVEELVGAPIDIISTGPDRNETI 424
>sp|Q2SBC8|PURA_HAHCH Adenylosuccinate synthetase OS=Hahella chejuensis (strain
KCTC 2396) GN=purA PE=3 SV=1
Length = 432
Score = 354 bits (907), Expect = 1e-096
Identities = 185/419 (44%), Positives = 250/419 (59%), Gaps = 2/419 (0%)
Frame = +1
Query: 289 VLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILNEDT 468
+LG QWGDEGKGK+VD+L + VAR QGG NAGHT+ +G+K LHL+PSGIL +
Sbjct: 7 ILGTQWGDEGKGKIVDLLTEEVAAVARFQGGHNAGHTLV-IDGQKTVLHLIPSGILRSNV 65
Query: 469 TCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVDGLRESELAKS 648
C+IGNGVV+ L EI LE GV + R+ +S L+ +H+ +D RE L +
Sbjct: 66 ACLIGNGVVLAPDALLSEIKTLEDKGVPVRQRLFLSPACPLILPYHKALDLAREERLGSA 125
Query: 649 FIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKL-EVLLADAAARFKGFKYSPEMLR 825
IGTT RGIGP Y KV R G+R+GDL + +KL E++ +K +P +
Sbjct: 126 KIGTTGRGIGPAYEDKVARRGVRLGDLAKPERFAEKLKEIMQYQNFVLEHYYKVAPIDYQ 185
Query: 826 EEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFVTSSSPS 1005
+ ++ + AE L P + D +++ + VL EG Q ++LDID GTYP+VTSS+ +
Sbjct: 186 KTLDETLKMAEELLPMMADVTDMLHEFRKRDENVLFEGAQGSLLDIDLGTYPYVTSSNTT 245
Query: 1006 AGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFGTTTGRP 1185
AGG TG G P + ++G+ KAY TRVGSGPFPTE G L G EFG TTGRP
Sbjct: 246 AGGTATGSGFGPMYLDYVLGITKAYATRVGSGPFPTELFDDVGAYLAKKGNEFGATTGRP 305
Query: 1186 RRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSFPGDLRL 1365
RRCGW D VALR + QIN + + LTKLDVL L+ +++ V Y+ +DG + P D
Sbjct: 306 RRCGWFDAVALRHAIQINSVSGICLTKLDVLDGLDVVKVCVGYRTADGAEITRPPIDCEA 365
Query: 1366 LEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPGRDALI 1542
E++ YE LPGWK ++ DLPK AQ Y+ +E+ + PI I GP R+ I
Sbjct: 366 FGEVEPVYEELPGWKESTFGVKRVEDLPKNAQDYIAFLEKQIEAPIDVISTGPDRNETI 424
>sp|Q7VKR5|PURA_HAEDU Adenylosuccinate synthetase OS=Haemophilus ducreyi GN=purA
PE=3 SV=1
Length = 432
Score = 348 bits (892), Expect = 8e-095
Identities = 182/415 (43%), Positives = 251/415 (60%), Gaps = 2/415 (0%)
Frame = +1
Query: 289 VLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILNEDT 468
+LG QWGDEGKGK+VD+L V R QGG NAGHT+ G+K L L+PSGIL E+
Sbjct: 7 ILGAQWGDEGKGKIVDLLTDRVKYVVRYQGGHNAGHTLI-INGEKTVLRLIPSGILRENV 65
Query: 469 TCVIGNGVVVHLPGLFKEIDGLESNGVSCKGRILVSDRAHLLFDFHQEVDGLRESELAKS 648
TC+IGNGVV+ L KE+ LE+ G++ + R+ +S+ L+ +H +D RE+ L K+
Sbjct: 66 TCLIGNGVVLSPEALMKEMGELEACGINVRERLKISEACPLILPYHVAMDHAREAALGKN 125
Query: 649 FIGTTKRGIGPCYSSKVIRNGIRVGDLRHMDTLPQKL-EVLLADAAARFKGFKYSPEMLR 825
IGTT RGIGP Y KV R G+RV DL + KL ++L +K P +
Sbjct: 126 KIGTTGRGIGPAYEDKVARRGLRVSDLFDKEAFATKLKDILDLYNFQLVHYYKVEPVDFQ 185
Query: 826 EEVEAYKRYAERLEPYITDTVHFMNDAISQKRRVLVEGGQATMLDIDFGTYPFVTSSSPS 1005
+ ++ A+ ++ + D ++ A + +L EG Q TMLDID GTYPFVTSS+ +
Sbjct: 186 KTLDDVFAVADVIKGMVADVTTLLHQARKEGVNILFEGAQGTMLDIDHGTYPFVTSSNTT 245
Query: 1006 AGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTENLGPGGDLLRLAGQEFGTTTGRP 1185
AGG+ TG G PR + ++G++KAY TRVGSGPF TE G+ + G EFG TGRP
Sbjct: 246 AGGVATGAGFGPRNLDYVLGIIKAYCTRVGSGPFTTELFNEEGETIARKGNEFGAVTGRP 305
Query: 1186 RRCGWLDLVALRFSCQINGFASLNLTKLDVLSDLEEIQLGVAYKKSDGTRVDSFPGDLRL 1365
RRCGW D VA+R + QIN + +TKLDVL E +++ AYK +G V+ P +
Sbjct: 306 RRCGWFDAVAVRRAVQINSISGFCMTKLDVLDGFETLKICTAYKMPNGEIVEYAPMAAKD 365
Query: 1366 LEELQVEYEVLPGWKFDISSIRNYADLPKAAQQYVERIEELVGVPIHYIGIGPGR 1530
E ++ YE +PGW + + Y LP+AA Y++RIEELVGVP+ + GP R
Sbjct: 366 WEGVEPIYETMPGWSENTFGVIKYEALPQAALDYIKRIEELVGVPVDILSTGPDR 420
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,154,264,487
Number of Sequences: 518415
Number of Extensions: 3154264487
Number of Successful Extensions: 47263005
Number of sequences better than 0.0: 0
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