BLASTX 7.6.2
Query= UN00918 /QuerySize=976
(975 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P49755|TMEDA_HUMAN Transmembrane emp24 domain-containing prot... 136 2e-031
sp|Q5E971|TMEDA_BOVIN Transmembrane emp24 domain-containing prot... 134 9e-031
sp|Q28735|TMEDA_RABIT Transmembrane emp24 domain-containing prot... 134 9e-031
sp|Q5RE32|TMEDA_PONAB Transmembrane emp24 domain-containing prot... 134 1e-030
sp|Q63584|TMEDA_RAT Transmembrane emp24 domain-containing protei... 133 3e-030
sp|O35587|TMEDA_MESAU Transmembrane protein Tmp21 OS=Mesocricetu... 131 7e-030
sp|Q9D1D4|TMEDA_MOUSE Transmembrane emp24 domain-containing prot... 130 2e-029
sp|Q90515|TMEDA_TAKRU Transmembrane emp24 domain-containing prot... 122 4e-027
sp|B3LVB0|TMEDA_DROAN Transmembrane emp24 domain-containing prot... 110 2e-023
sp|B4JYU5|TMEDA_DROGR Transmembrane emp24 domain-containing prot... 108 7e-023
sp|B4GE47|TMEDA_DROPE Transmembrane emp24 domain-containing prot... 106 3e-022
sp|Q5A302|TMEDA_CANAL Endoplasmic reticulum vesicle protein 25 O... 105 6e-022
sp|B4K4G5|TMEDA_DROMO Transmembrane emp24 domain-containing prot... 104 1e-021
sp|A0AQ71|TMEDA_DROSI Transmembrane emp24 domain-containing prot... 104 2e-021
sp|B4MGF8|TMEDA_DROVI Transmembrane emp24 domain-containing prot... 104 2e-021
sp|B3P6T8|TMEDA_DROER Transmembrane emp24 domain-containing prot... 103 2e-021
sp|B4PUZ3|TMEDA_DROYA Transmembrane emp24 domain-containing prot... 103 2e-021
sp|B4NIY1|TMEDA_DROWI Transmembrane emp24 domain-containing prot... 103 3e-021
sp|Q8SXY6|TMEDA_DROME Transmembrane emp24 domain-containing prot... 102 5e-021
sp|Q6BTC2|TMEDA_DEBHA Endoplasmic reticulum vesicle protein 25 O... 91 8e-018
>sp|P49755|TMEDA_HUMAN Transmembrane emp24 domain-containing protein 10 OS=Homo
sapiens GN=TMED10 PE=1 SV=2
Length = 219
Score = 136 bits (342), Expect = 2e-031
Identities = 80/218 (36%), Positives = 129/218 (59%), Gaps = 4/218 (1%)
Frame = +1
Query: 79 SFPMAIRGIFAISTAVLLLFLLTINHGEAIWLTIPATGGTKCVSEEIQSNVVVLADYYVV 258
S P A RG F + A+LLLFLL AI +P KC+ EEI +++V Y +
Sbjct: 5 SGPPARRGPFPL--ALLLLFLLGPRLVLAISFHLP-INSRKCLREEIHKDLLVTGAYEIS 61
Query: 259 DEQNPGNTPAVSAKVTSPYGNDLHHQENVTHGQFAFTTQETGNYLACFSVDSSHPLPNPL 438
D+ K+T G+ L+ +E+ T G+FAFTT++ + CF + +P+ L
Sbjct: 62 DQSGGAGGLRSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQL 121
Query: 439 TLGIDWKTGIATKDWDSVAKKEKIEGVDLQLTRLEGLVQAIRENINYIKNREGEMREVSE 618
+ +D K G+ K+++ +AK EK++ ++++L RLE L ++I + Y+K RE EMR+ +E
Sbjct: 122 VI-LDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNE 180
Query: 619 ATNARVAWFSIMSLGVCLSVAGVQIWYLKRYFYKKKLI 732
+TN RV +FSI S+ + +A Q++YL+R+F KKLI
Sbjct: 181 STNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLI 218
>sp|Q5E971|TMEDA_BOVIN Transmembrane emp24 domain-containing protein 10 OS=Bos
taurus GN=TMED10 PE=2 SV=1
Length = 219
Score = 134 bits (337), Expect = 9e-031
Identities = 78/218 (35%), Positives = 127/218 (58%), Gaps = 4/218 (1%)
Frame = +1
Query: 79 SFPMAIRGIFAISTAVLLLFLLTINHGEAIWLTIPATGGTKCVSEEIQSNVVVLADYYVV 258
S P A RG A+LLL LL + AI +P KC+ EEI +++V Y +
Sbjct: 5 SGPQAQRG--PCPFALLLLLLLGPSSVLAISFHLP-VNSRKCLREEIHKDLLVTGAYEIT 61
Query: 259 DEQNPGNTPAVSAKVTSPYGNDLHHQENVTHGQFAFTTQETGNYLACFSVDSSHPLPNPL 438
D+ K+T G+ L+ +E+ T G+FAFTT++ + CF + +P+ L
Sbjct: 62 DQSGGAGGLRTHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQL 121
Query: 439 TLGIDWKTGIATKDWDSVAKKEKIEGVDLQLTRLEGLVQAIRENINYIKNREGEMREVSE 618
+ +D K G+ K+++ +AK EK++ ++++L RLE L ++I + Y+K RE EMR+ +E
Sbjct: 122 VI-LDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNE 180
Query: 619 ATNARVAWFSIMSLGVCLSVAGVQIWYLKRYFYKKKLI 732
+TN RV +FSI S+ + +A Q++YL+R+F KKLI
Sbjct: 181 STNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLI 218
>sp|Q28735|TMEDA_RABIT Transmembrane emp24 domain-containing protein 10
OS=Oryctolagus cuniculus GN=TMED10 PE=1 SV=1
Length = 219
Score = 134 bits (337), Expect = 9e-031
Identities = 77/218 (35%), Positives = 129/218 (59%), Gaps = 4/218 (1%)
Frame = +1
Query: 79 SFPMAIRGIFAISTAVLLLFLLTINHGEAIWLTIPATGGTKCVSEEIQSNVVVLADYYVV 258
S P+A RG + A+L LFLL + AI +P KC+ EEI +++V Y +
Sbjct: 5 SGPLARRGPGPL--ALLFLFLLGPSSVLAISFHLP-VNSRKCLREEIHKDLLVTGAYEIT 61
Query: 259 DEQNPGNTPAVSAKVTSPYGNDLHHQENVTHGQFAFTTQETGNYLACFSVDSSHPLPNPL 438
D+ K+T G+ L+ +E+ + G+FAFTT++ + CF + +P+ L
Sbjct: 62 DQSGGAGGLRTHLKITDSAGHILYSKEDASKGKFAFTTEDYDMFEVCFESKGTGRIPDQL 121
Query: 439 TLGIDWKTGIATKDWDSVAKKEKIEGVDLQLTRLEGLVQAIRENINYIKNREGEMREVSE 618
+ +D K G+ K+++ +AK EK++ ++++L RLE L ++I + Y+K RE EMR+ +E
Sbjct: 122 VI-LDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNE 180
Query: 619 ATNARVAWFSIMSLGVCLSVAGVQIWYLKRYFYKKKLI 732
+TN RV +FSI S+ + +A Q++YL+R+F KKLI
Sbjct: 181 STNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLI 218
>sp|Q5RE32|TMEDA_PONAB Transmembrane emp24 domain-containing protein 10 OS=Pongo
abelii GN=TMED10 PE=2 SV=1
Length = 219
Score = 134 bits (335), Expect = 1e-030
Identities = 78/218 (35%), Positives = 129/218 (59%), Gaps = 4/218 (1%)
Frame = +1
Query: 79 SFPMAIRGIFAISTAVLLLFLLTINHGEAIWLTIPATGGTKCVSEEIQSNVVVLADYYVV 258
S P RG F + A+LLLFLL + AI +P KC+ EEI +++V Y +
Sbjct: 5 SGPPTRRGPFPL--ALLLLFLLGPSLVLAISFHLP-INSRKCLREEIHKDLLVTGAYEIS 61
Query: 259 DEQNPGNTPAVSAKVTSPYGNDLHHQENVTHGQFAFTTQETGNYLACFSVDSSHPLPNPL 438
D+ K+T G+ L+ +E+ T G+FAFTT++ + CF + +P+ L
Sbjct: 62 DQSGGAGGLRSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQL 121
Query: 439 TLGIDWKTGIATKDWDSVAKKEKIEGVDLQLTRLEGLVQAIRENINYIKNREGEMREVSE 618
+ +D K G+ K+++ +AK EK++ ++++L RLE L ++I + Y++ RE EMR+ +E
Sbjct: 122 VI-LDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMEKREEEMRDTNE 180
Query: 619 ATNARVAWFSIMSLGVCLSVAGVQIWYLKRYFYKKKLI 732
+TN RV +FSI S+ + +A Q++YL+R+F KKLI
Sbjct: 181 STNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLI 218
>sp|Q63584|TMEDA_RAT Transmembrane emp24 domain-containing protein 10 OS=Rattus
norvegicus GN=Tmed10 PE=1 SV=2
Length = 219
Score = 133 bits (333), Expect = 3e-030
Identities = 72/205 (35%), Positives = 122/205 (59%), Gaps = 2/205 (0%)
Frame = +1
Query: 118 TAVLLLFLLTINHGEAIWLTIPATGGTKCVSEEIQSNVVVLADYYVVDEQNPGNTPAVSA 297
+A+L LFLL + I +P KC+ EEI +++V Y + D+
Sbjct: 16 SALLFLFLLGPSSVLGISFHLP-VNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHL 74
Query: 298 KVTSPYGNDLHHQENVTHGQFAFTTQETGNYLACFSVDSSHPLPNPLTLGIDWKTGIATK 477
K+T G+ L+ +E+ T G+FAFTT++ + CF + +P+ L + +D K G+ K
Sbjct: 75 KITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVI-LDMKHGVEAK 133
Query: 478 DWDSVAKKEKIEGVDLQLTRLEGLVQAIRENINYIKNREGEMREVSEATNARVAWFSIMS 657
+++ +AK EK++ ++++L RLE L ++I + Y+K RE EMR+ +E+TN RV +FSI S
Sbjct: 134 NYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFS 193
Query: 658 LGVCLSVAGVQIWYLKRYFYKKKLI 732
+ + +A Q++YL+R+F KKLI
Sbjct: 194 MFCLIGLATWQVFYLRRFFKAKKLI 218
>sp|O35587|TMEDA_MESAU Transmembrane protein Tmp21 OS=Mesocricetus auratus
GN=TMED10 PE=2 SV=1
Length = 219
Score = 131 bits (329), Expect = 7e-030
Identities = 72/204 (35%), Positives = 121/204 (59%), Gaps = 2/204 (0%)
Frame = +1
Query: 121 AVLLLFLLTINHGEAIWLTIPATGGTKCVSEEIQSNVVVLADYYVVDEQNPGNTPAVSAK 300
A+L L LL + AI +P KC+ EEI +++V Y + D+ K
Sbjct: 17 ALLFLLLLGPSSVLAISFHLP-VNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLK 75
Query: 301 VTSPYGNDLHHQENVTHGQFAFTTQETGNYLACFSVDSSHPLPNPLTLGIDWKTGIATKD 480
+T G+ L+ +E+ T G+FAFTT++ + CF + +P+ L + +D K G+ K+
Sbjct: 76 ITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVI-LDMKHGVEAKN 134
Query: 481 WDSVAKKEKIEGVDLQLTRLEGLVQAIRENINYIKNREGEMREVSEATNARVAWFSIMSL 660
++ +AK EK++ ++++L RLE L ++I + Y+K RE EMR+ +E+TN RV +FSI S+
Sbjct: 135 YEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSM 194
Query: 661 GVCLSVAGVQIWYLKRYFYKKKLI 732
+ +A Q++YL+R+F KKLI
Sbjct: 195 LCLIGLATWQVFYLRRFFKAKKLI 218
>sp|Q9D1D4|TMEDA_MOUSE Transmembrane emp24 domain-containing protein 10 OS=Mus
musculus GN=Tmed10 PE=2 SV=1
Length = 219
Score = 130 bits (325), Expect = 2e-029
Identities = 68/201 (33%), Positives = 118/201 (58%), Gaps = 2/201 (0%)
Frame = +1
Query: 133 LFLLTINHGEAIWLTIP-ATGGTKCVSEEIQSNVVVLADYYVVDEQNPGNTPAVSAKVTS 309
LFLL + + ++ KC+ EEI +++V Y + D+ K+T
Sbjct: 19 LFLLLLGPSSVLGISFHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITD 78
Query: 310 PYGNDLHHQENVTHGQFAFTTQETGNYLACFSVDSSHPLPNPLTLGIDWKTGIATKDWDS 489
G+ L+ +E+ T G+FAFTT++ + CF + +P+ L + +D K G+ K+++
Sbjct: 79 SAGHILYAKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVI-LDMKHGVEAKNYEE 137
Query: 490 VAKKEKIEGVDLQLTRLEGLVQAIRENINYIKNREGEMREVSEATNARVAWFSIMSLGVC 669
+AK EK++ ++++L RLE L ++I + Y+K RE EMR+ +E+TN RV +FSI S+
Sbjct: 138 IAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCL 197
Query: 670 LSVAGVQIWYLKRYFYKKKLI 732
+ +A Q++YL+R+F KKLI
Sbjct: 198 IGLATWQVFYLRRFFKAKKLI 218
>sp|Q90515|TMEDA_TAKRU Transmembrane emp24 domain-containing protein 10
OS=Takifugu rubripes GN=tmed10 PE=3 SV=1
Length = 213
Score = 122 bits (305), Expect = 4e-027
Identities = 72/211 (34%), Positives = 125/211 (59%), Gaps = 9/211 (4%)
Frame = +1
Query: 118 TAVLLLFLLTINHGEAIWLTIPATGGTKCVSEEIQSNVVVLADYYVVDEQNPGNTPAVSA 297
TA+L L +L I +I +P KC+ EEI +V+V +Y + ++ +T +
Sbjct: 5 TALLFLPVL-IESAFSISFFLP-VNTRKCLREEIHKDVLVTGEYEISEQVVTVHTSSTVV 62
Query: 298 ------KVTSPYGNDLHHQENVTHGQFAFTTQETGNYLACFSVDSSHPLPNPLTLGIDWK 459
K+T + L+ +E+ T G+FAFTT++ + CF + +P+ L + +D K
Sbjct: 63 GDGSIFKITDSSSHTLYSKEDATKGKFAFTTEDYDMFEVCFESKCTGRVPDQL-VNLDMK 121
Query: 460 TGIATKDWDSVAKKEKIEGVDLQLTRLEGLVQAIRENINYIKNREGEMREVSEATNARVA 639
G+ K+++ +AK EK++ ++++L RLE L ++I + Y+K RE EMR+ +E+TN RV
Sbjct: 122 HGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVL 181
Query: 640 WFSIMSLGVCLSVAGVQIWYLKRYFYKKKLI 732
+FSI S+ + +A Q++YL+R+F KKLI
Sbjct: 182 YFSIFSMFCLIGLATWQVFYLRRFFKAKKLI 212
>sp|B3LVB0|TMEDA_DROAN Transmembrane emp24 domain-containing protein bai
OS=Drosophila ananassae GN=bai PE=3 SV=1
Length = 206
Score = 110 bits (274), Expect = 2e-023
Identities = 68/193 (35%), Positives = 108/193 (55%), Gaps = 6/193 (3%)
Frame = +1
Query: 157 GEAIWLTIPATGGTKCVSEEIQSNVVVLADYYVVDEQNPGNTPAVSAKVTSPYGNDLHHQ 336
GEA+ + KC+ E+IQ+N +V+ +Y V D PG A+ T G+ L Q
Sbjct: 18 GEAVMFKL-TPNTQKCLKEDIQANQLVIGEYEVSDV--PGQVIDYIARDTK--GHILSQQ 72
Query: 337 ENVTHGQFAFTTQETGNYLACF-SVDSSHPLPNPLTLGIDWKTGIATKDWDSVAKKEKIE 513
E++T G+F+F ++ Y CF S H P + + K G+ TK ++ + + K++
Sbjct: 73 EHITKGKFSFMSEVYDAYEICFISKVPPHQRGIPQEVSLSTKKGVETKSYEGIGEASKLK 132
Query: 514 GVDLQLTRLEGLVQAIRENINYIKNREGEMREVSEATNARVAWFSIMSLGVCLSVAGVQI 693
+++ L RLE L +I + ++ RE EMR+ +E TN+RV +FSI S+ L +A Q+
Sbjct: 133 PLEVDLKRLEDLSDSIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQV 192
Query: 694 WYLKRYFYKKKLI 732
YL+RYF KKLI
Sbjct: 193 LYLRRYFKAKKLI 205
>sp|B4JYU5|TMEDA_DROGR Transmembrane emp24 domain-containing protein bai
OS=Drosophila grimshawi GN=bai PE=3 SV=2
Length = 206
Score = 108 bits (269), Expect = 7e-023
Identities = 74/205 (36%), Positives = 116/205 (56%), Gaps = 9/205 (4%)
Frame = +1
Query: 124 VLLLF-LLTINHGEAIWLTIPATGGTKCVSEEIQSNVVVLADYYVVDEQNPGNTPAVSAK 300
+LL+F L HG LT P T KC+ E+IQ+N +V+ +Y V D PG A+
Sbjct: 8 ILLIFGCLCRIHGVMFHLT-PNT--QKCLKEDIQANQLVMGEYEVSDV--PGQIIDYIAR 62
Query: 301 VTSPYGNDLHHQENVTHGQFAFTTQETGNYLACF-SVDSSHPLPNPLTLGIDWKTGIATK 477
T G+ L +E++T G+F+FT++ Y CF S H + + K G+ TK
Sbjct: 63 DTK--GHILSQKEHITKGKFSFTSEVFDAYEICFISKVPPHQRGISQEVSLVTKKGVETK 120
Query: 478 DWDSVAKKEKIEGVDLQLTRLEGLVQAIRENINYIKNREGEMREVSEATNARVAWFSIMS 657
+++ + + K++ +++ L RLE L +I + ++ RE EMR+ +E TN+RV +FSI S
Sbjct: 121 NYEGIGEASKLKPLEVDLKRLEDLSDSIVRDFAVMRKREEEMRDTNEKTNSRVLFFSIFS 180
Query: 658 LGVCLSVAGVQIWYLKRYFYKKKLI 732
+ L +A Q+ YL+RYF KKLI
Sbjct: 181 MCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|B4GE47|TMEDA_DROPE Transmembrane emp24 domain-containing protein bai
OS=Drosophila persimilis GN=bai PE=3 SV=1
Length = 206
Score = 106 bits (264), Expect = 3e-022
Identities = 64/179 (35%), Positives = 103/179 (57%), Gaps = 5/179 (2%)
Frame = +1
Query: 199 KCVSEEIQSNVVVLADYYVVDEQNPGNTPAVSAKVTSPYGNDLHHQENVTHGQFAFTTQE 378
KC+ E+IQ+N +V+ +Y V D PG A+ T G+ L +E++T G+F+F ++
Sbjct: 31 KCLKEDIQANQLVMGEYEVSDV--PGQIIDYVARDTK--GHILSQKEHITKGKFSFMSEV 86
Query: 379 TGNYLACF-SVDSSHPLPNPLTLGIDWKTGIATKDWDSVAKKEKIEGVDLQLTRLEGLVQ 555
Y CF S H P + + K G+ TK ++ + + K++ +++ L RLE L
Sbjct: 87 YDAYEICFISKVPPHQRGIPQEVSLVTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLSD 146
Query: 556 AIRENINYIKNREGEMREVSEATNARVAWFSIMSLGVCLSVAGVQIWYLKRYFYKKKLI 732
+I + ++ RE EMR+ +E TN+RV +FSI S+ L +A Q+ YL+RYF KKLI
Sbjct: 147 SIVRDFILMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|Q5A302|TMEDA_CANAL Endoplasmic reticulum vesicle protein 25 OS=Candida
albicans GN=ERV25 PE=3 SV=1
Length = 215
Score = 105 bits (261), Expect = 6e-022
Identities = 62/215 (28%), Positives = 119/215 (55%), Gaps = 9/215 (4%)
Frame = +1
Query: 109 AISTAVLLLFLLTINHGEAIWLTIPATGGTK--CVSEEIQSNVVVLADYYVVDEQNPGNT 282
++ T + L+F L ++ + L +PA + C+ + +Q N +V+ + + + + G+
Sbjct: 3 SLITYIALVFSLFVSSAIGLHLEVPALPNPQPVCIRDFVQENQMVVVN--IKTDGSKGDG 60
Query: 283 PAVSAKVTSPYGNDLHHQENVT-HGQFAFTTQETGNYLACFS--VDS--SHPLPNPLTLG 447
+ KVT GN+ ++++V H AFT+Q C + +D+ S ++
Sbjct: 61 QRLDLKVTDSLGNEYRNKKDVVGHANVAFTSQHNAAIDICLTNYLDNKWSKHQQTVRSVE 120
Query: 448 IDWKTGIATKDWDSVAKKEKIEGVDLQLTRLEGLVQAIRENINYIKNREGEMREVSEATN 627
+D ++G A +DW+++ EK++ V+++L R+E + + I E + Y+K RE MR+ +E+TN
Sbjct: 121 LDIESGAAARDWNALQASEKLKPVEVELKRIESITEEIVEELRYLKAREERMRDTNESTN 180
Query: 628 ARVAWFSIMSLGVCLSVAGVQIWYLKRYFYKKKLI 732
+RV WFSI+ + + QI YL+ YF K +I
Sbjct: 181 SRVKWFSIVVIASLVGFGVWQIQYLRHYFKVKHII 215
>sp|B4K4G5|TMEDA_DROMO Transmembrane emp24 domain-containing protein bai
OS=Drosophila mojavensis GN=bai PE=3 SV=1
Length = 206
Score = 104 bits (258), Expect = 1e-021
Identities = 63/179 (35%), Positives = 102/179 (56%), Gaps = 5/179 (2%)
Frame = +1
Query: 199 KCVSEEIQSNVVVLADYYVVDEQNPGNTPAVSAKVTSPYGNDLHHQENVTHGQFAFTTQE 378
KC+ E+IQ+N +V+ +Y V D PG A+ T G+ L +E++T G+F+F ++
Sbjct: 31 KCLKEDIQANQLVMGEYEVSDV--PGQVIDYIARDTK--GHILSQKEHITKGKFSFMSEV 86
Query: 379 TGNYLACF-SVDSSHPLPNPLTLGIDWKTGIATKDWDSVAKKEKIEGVDLQLTRLEGLVQ 555
Y CF S H + + K G+ TK ++ + + K++ +++ L RLE L
Sbjct: 87 YDAYEICFISKVPPHQRGISQEVSLVTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLSD 146
Query: 556 AIRENINYIKNREGEMREVSEATNARVAWFSIMSLGVCLSVAGVQIWYLKRYFYKKKLI 732
+I + ++ RE EMR+ +E TN+RV +FSI S+ L +A Q+ YL+RYF KKLI
Sbjct: 147 SIVRDFALMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|A0AQ71|TMEDA_DROSI Transmembrane emp24 domain-containing protein bai
OS=Drosophila simulans GN=bai PE=3 SV=1
Length = 206
Score = 104 bits (257), Expect = 2e-021
Identities = 63/179 (35%), Positives = 103/179 (57%), Gaps = 5/179 (2%)
Frame = +1
Query: 199 KCVSEEIQSNVVVLADYYVVDEQNPGNTPAVSAKVTSPYGNDLHHQENVTHGQFAFTTQE 378
KC+ E+IQ+N +V+ +Y V D PG A+ T G+ L +E++T G+F+F ++
Sbjct: 31 KCLKEDIQANQLVMGEYEVSDV--PGQIIDYIARDTK--GHILSQKEHITKGKFSFMSEV 86
Query: 379 TGNYLACF-SVDSSHPLPNPLTLGIDWKTGIATKDWDSVAKKEKIEGVDLQLTRLEGLVQ 555
Y CF S +H + + K G+ TK ++ + + K++ +++ L RLE L
Sbjct: 87 YETYEICFISKVPAHQRGVVQEVSLLTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLSD 146
Query: 556 AIRENINYIKNREGEMREVSEATNARVAWFSIMSLGVCLSVAGVQIWYLKRYFYKKKLI 732
+I + ++ RE EMR+ +E TN+RV +FSI S+ L +A Q+ YL+RYF KKLI
Sbjct: 147 SIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|B4MGF8|TMEDA_DROVI Transmembrane emp24 domain-containing protein bai
OS=Drosophila virilis GN=bai PE=3 SV=1
Length = 206
Score = 104 bits (257), Expect = 2e-021
Identities = 63/179 (35%), Positives = 102/179 (56%), Gaps = 5/179 (2%)
Frame = +1
Query: 199 KCVSEEIQSNVVVLADYYVVDEQNPGNTPAVSAKVTSPYGNDLHHQENVTHGQFAFTTQE 378
KC+ E+IQ+N +V+ +Y V D PG A+ T G+ L +E++T G+F+F ++
Sbjct: 31 KCLKEDIQANQLVMGEYEVSDV--PGQIIDYIARDTK--GHILSQKEHITKGKFSFMSEV 86
Query: 379 TGNYLACF-SVDSSHPLPNPLTLGIDWKTGIATKDWDSVAKKEKIEGVDLQLTRLEGLVQ 555
Y CF S H + + K G+ TK ++ + + K++ +++ L RLE L
Sbjct: 87 YDAYEICFISKVPPHQRGISQEVSLVTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLSD 146
Query: 556 AIRENINYIKNREGEMREVSEATNARVAWFSIMSLGVCLSVAGVQIWYLKRYFYKKKLI 732
+I + ++ RE EMR+ +E TN+RV +FSI S+ L +A Q+ YL+RYF KKLI
Sbjct: 147 SIVRDFALMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|B3P6T8|TMEDA_DROER Transmembrane emp24 domain-containing protein bai
OS=Drosophila erecta GN=bai PE=3 SV=1
Length = 206
Score = 103 bits (256), Expect = 2e-021
Identities = 63/179 (35%), Positives = 103/179 (57%), Gaps = 5/179 (2%)
Frame = +1
Query: 199 KCVSEEIQSNVVVLADYYVVDEQNPGNTPAVSAKVTSPYGNDLHHQENVTHGQFAFTTQE 378
KC+ E+IQ+N +V+ +Y V D PG A+ T G+ L +E++T G+F+F ++
Sbjct: 31 KCLKEDIQANQLVMGEYEVSDV--PGQIIDYIARDTK--GHILSQKEHITKGKFSFMSEV 86
Query: 379 TGNYLACF-SVDSSHPLPNPLTLGIDWKTGIATKDWDSVAKKEKIEGVDLQLTRLEGLVQ 555
Y CF S +H + + K G+ TK ++ + + K++ +++ L RLE L
Sbjct: 87 YDAYEICFISKVPAHQRGIVQEVSLLTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLSD 146
Query: 556 AIRENINYIKNREGEMREVSEATNARVAWFSIMSLGVCLSVAGVQIWYLKRYFYKKKLI 732
+I + ++ RE EMR+ +E TN+RV +FSI S+ L +A Q+ YL+RYF KKLI
Sbjct: 147 SIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|B4PUZ3|TMEDA_DROYA Transmembrane emp24 domain-containing protein bai
OS=Drosophila yakuba GN=bai PE=3 SV=1
Length = 206
Score = 103 bits (256), Expect = 2e-021
Identities = 63/179 (35%), Positives = 103/179 (57%), Gaps = 5/179 (2%)
Frame = +1
Query: 199 KCVSEEIQSNVVVLADYYVVDEQNPGNTPAVSAKVTSPYGNDLHHQENVTHGQFAFTTQE 378
KC+ E+IQ+N +V+ +Y V D PG A+ T G+ L +E++T G+F+F ++
Sbjct: 31 KCLKEDIQANQLVMGEYEVSDV--PGQIIDYIARDTK--GHILSQKEHITKGKFSFMSEV 86
Query: 379 TGNYLACF-SVDSSHPLPNPLTLGIDWKTGIATKDWDSVAKKEKIEGVDLQLTRLEGLVQ 555
Y CF S +H + + K G+ TK ++ + + K++ +++ L RLE L
Sbjct: 87 YDAYEICFISKVPAHQRGIVQEVSLLTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLSD 146
Query: 556 AIRENINYIKNREGEMREVSEATNARVAWFSIMSLGVCLSVAGVQIWYLKRYFYKKKLI 732
+I + ++ RE EMR+ +E TN+RV +FSI S+ L +A Q+ YL+RYF KKLI
Sbjct: 147 SIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|B4NIY1|TMEDA_DROWI Transmembrane emp24 domain-containing protein bai
OS=Drosophila willistoni GN=bai PE=3 SV=1
Length = 206
Score = 103 bits (255), Expect = 3e-021
Identities = 61/179 (34%), Positives = 102/179 (56%), Gaps = 5/179 (2%)
Frame = +1
Query: 199 KCVSEEIQSNVVVLADYYVVDEQNPGNTPAVSAKVTSPYGNDLHHQENVTHGQFAFTTQE 378
KC+ E+IQ+N +V+ +Y V D PG + V G+ L +E++T +F+F ++
Sbjct: 31 KCLKEDIQANQMVMGEYEVSDV--PGQ--VIDFIVRDTKGHILSQKEHITKAKFSFMSEV 86
Query: 379 TGNYLACF-SVDSSHPLPNPLTLGIDWKTGIATKDWDSVAKKEKIEGVDLQLTRLEGLVQ 555
+Y CF S H + + K G+ TK+++ + + K++ +++ L RLE L
Sbjct: 87 YDSYEICFISKVPPHQRGIAQQVALTTKKGVETKNYEGIGEASKLKPLEVDLKRLEDLSD 146
Query: 556 AIRENINYIKNREGEMREVSEATNARVAWFSIMSLGVCLSVAGVQIWYLKRYFYKKKLI 732
+I + ++ RE EMR+ +E TN+RV +FSI S+ L +A Q+ YL+RYF KKLI
Sbjct: 147 SIVRDFVMMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|Q8SXY6|TMEDA_DROME Transmembrane emp24 domain-containing protein bai
OS=Drosophila melanogaster GN=bai PE=2 SV=1
Length = 206
Score = 102 bits (253), Expect = 5e-021
Identities = 62/179 (34%), Positives = 103/179 (57%), Gaps = 5/179 (2%)
Frame = +1
Query: 199 KCVSEEIQSNVVVLADYYVVDEQNPGNTPAVSAKVTSPYGNDLHHQENVTHGQFAFTTQE 378
KC+ E+IQ+N +V+ ++ V D PG A+ T G+ L +E++T G+F+F ++
Sbjct: 31 KCLKEDIQANQLVMGEFEVSDV--PGQIIDYIARDTK--GHILSQKEHITKGKFSFMSEV 86
Query: 379 TGNYLACF-SVDSSHPLPNPLTLGIDWKTGIATKDWDSVAKKEKIEGVDLQLTRLEGLVQ 555
Y CF S +H + + K G+ TK ++ + + K++ +++ L RLE L
Sbjct: 87 YDTYEICFISKVPAHQRGVIQEVSLLTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLSD 146
Query: 556 AIRENINYIKNREGEMREVSEATNARVAWFSIMSLGVCLSVAGVQIWYLKRYFYKKKLI 732
+I + ++ RE EMR+ +E TN+RV +FSI S+ L +A Q+ YL+RYF KKLI
Sbjct: 147 SIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|Q6BTC2|TMEDA_DEBHA Endoplasmic reticulum vesicle protein 25 OS=Debaryomyces
hansenii GN=ERV25 PE=3 SV=2
Length = 214
Score = 91 bits (225), Expect = 8e-018
Identities = 56/210 (26%), Positives = 106/210 (50%), Gaps = 11/210 (5%)
Frame = +1
Query: 130 LLFLLT--INHGEAIWLTIPATGGTK--CVSEEIQSNVVVLADYYVVDEQNPGNTPAVSA 297
LLF+++ I+ A+ L IPAT C+ + +Q +V+ + + N G+ +
Sbjct: 7 LLFIISTFISLVSALQLAIPATTNPDPFCIRDFVQEEQMVVVN--IKTNGNSGDGQRLDL 64
Query: 298 KVTSPYGNDLHHQENVTHG-QFAFTTQETGNYLACFSVDSSHPLPNPLT----LGIDWKT 462
++ GN+ + ++ + FT+ + + CF+ + +D ++
Sbjct: 65 RIVDSLGNEYRRKNDIAGSVKIGFTSHNSAAFDICFTNQLERKWSKNTNFVREIELDVES 124
Query: 463 GIATKDWDSVAKKEKIEGVDLQLTRLEGLVQAIRENINYIKNREGEMREVSEATNARVAW 642
G A +DW++V EK++ V++ L R+E I + Y+K RE MR+ +E+TN+RV W
Sbjct: 125 GAAARDWNAVQAAEKLKPVEVDLRRIEETTYEISGELQYLKAREERMRDTNESTNSRVKW 184
Query: 643 FSIMSLGVCLSVAGVQIWYLKRYFYKKKLI 732
FSI+ + + + Q+ YL+ YF K +I
Sbjct: 185 FSILVITSLVGLGAWQVQYLRHYFKVKHII 214
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,106,165,710
Number of Sequences: 518415
Number of Extensions: 6106165710
Number of Successful Extensions: 55409465
Number of sequences better than 0.0: 0
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