BLASTX 7.6.2
Query= UN00977 /QuerySize=1304
(1303 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q20390|PPT1_CAEEL Palmitoyl-protein thioesterase 1 OS=Caenorh... 162 6e-039
sp|Q54CM0|PPT3_DICDI Palmitoyl-protein thioesterase 3 OS=Dictyos... 159 4e-038
sp|P45479|PPT1_RAT Palmitoyl-protein thioesterase 1 OS=Rattus no... 149 5e-035
sp|O88531|PPT1_MOUSE Palmitoyl-protein thioesterase 1 OS=Mus mus... 148 1e-034
sp|O59747|PDF1_SCHPO Palmitoyl-protein thioesterase-dolichyl pyr... 125 1e-027
sp|Q9VKH6|PPT2_DROME Lysosomal thioesterase PPT2 homolog OS=Dros... 89 5e-017
sp|Q6GNY7|PPT2B_XENLA Lysosomal thioesterase PPT2-B OS=Xenopus l... 75 9e-013
>sp|Q20390|PPT1_CAEEL Palmitoyl-protein thioesterase 1 OS=Caenorhabditis elegans
GN=ppt-1 PE=2 SV=2
Length = 298
Score = 162 bits (409), Expect = 6e-039
Identities = 83/210 (39%), Positives = 125/210 (59%), Gaps = 3/210 (1%)
Frame = -3
Query: 917 VVCEKVKSMPELSDGYSIVGLSQGNMIGRALIEFCDDAPPVKSFVSIGGPHAGTASIPFC 738
+ C K+K+ PEL +GY+ +G SQG RA+ + C + PP+K+ VS+GG H G P+C
Sbjct: 86 MACIKIKNDPELKNGYNAIGFSQGAQFLRAVAQRCPN-PPMKNLVSVGGQHQGVFGAPYC 144
Query: 737 -GVTWICIMLDSMIKTEIYSDYMQEHLAPSGFLKIPTDIAGYMEGCRFLPKLNNELPVKN 561
G +C + +I Y ++Q+ + + + P + Y + FL +NNE N
Sbjct: 145 IGDNIMCNGVRRLIDLGAYLPFVQKRVVQAQYWHDPNQVEEYKKRSIFLADINNE-NNNN 203
Query: 560 STYKERFSSLENLVLIMFEHDTILIPKETSWFGYYPDGSFKTILPPQETKLYTEDWIGLR 381
TYK SL+NLVL+ F D +++PK++SWFG+Y DG TILP ET LY ED IGL+
Sbjct: 204 PTYKRNLLSLKNLVLVKFNQDHMVVPKDSSWFGFYKDGDIDTILPMNETDLYKEDRIGLK 263
Query: 380 ALDEAGKVKFVNVSGNHLQISHEDMKKHIV 291
L E+G++ F++V G+HLQI + I+
Sbjct: 264 KLHESGRIHFMDVDGDHLQIPRSVLVNDII 293
>sp|Q54CM0|PPT3_DICDI Palmitoyl-protein thioesterase 3 OS=Dictyostelium
discoideum GN=ppt3 PE=3 SV=1
Length = 289
Score = 159 bits (402), Expect = 4e-038
Identities = 97/290 (33%), Positives = 157/290 (54%), Gaps = 20/290 (6%)
Frame = -3
Query: 1127 TIIALICTFITVASSV-PFIVLHGIGDKCSNSGVKHFTELLSDW---SSSQGYCL--EIG 966
++I LI I + S+ P +++HG+ + K E L W S Y L EIG
Sbjct: 6 SLILLIALAIALVSATRPVVLMHGV------TTGKESMEPLKSWIEESIPDIYVLNVEIG 59
Query: 965 SGSWDSWTMPLLDQTAVVCEKVKSMPELSDGYSIVGLSQGNMIGRALIEFCDDAPPVKSF 786
+G++DS + Q + V++ P+L++G++++G SQG +I RA ++ ++ P V ++
Sbjct: 60 NGAFDSIFTTMDSQIEEFAQVVQADPKLANGFNLIGFSQGTLIARAFVQRYNN-PQVYNY 118
Query: 785 VSIGGPHAGTASIPFCGVTWICIMLDSMIKTEIYSDYMQEHLAPSGFLKIPTDIAGYMEG 606
+S GP G PF + W+ D ++ T Y +Q+ L+ + + K P I Y+E
Sbjct: 119 ISWNGPQGGQFGTPFVNIPWV----DKVLGTIPYEKTIQKKLSVAEYWKDPHRIDKYLER 174
Query: 605 CRFLPKLNNELPVKNSTYKERFSSLENLVLIMFEHDTILIPKETSWFGYYPDGSFKTILP 426
FL +NNE VKN+TYKE + L +VL +D +IPKE+ WF +Y DGS ++P
Sbjct: 175 SIFLADINNEYQVKNTTYKENLTKLNAMVLTYSTNDKTIIPKESGWFSFYADGSGTEVVP 234
Query: 425 PQETKLYTEDWIGLRALDEAGKVKFVNVSGNHLQISHEDMKKHIVPYLSD 276
Q+ Y+EDW+GLR LDE+ ++ F + H ED K PY ++
Sbjct: 235 LQQQTQYSEDWLGLRTLDESNRLFFYTTTCTHRDHPIEDYCK---PYFTN 281
>sp|P45479|PPT1_RAT Palmitoyl-protein thioesterase 1 OS=Rattus norvegicus
GN=Ppt1 PE=1 SV=1
Length = 306
Score = 149 bits (375), Expect = 5e-035
Identities = 78/217 (35%), Positives = 121/217 (55%), Gaps = 4/217 (1%)
Frame = -3
Query: 926 QTAVVCEKVKSMPELSDGYSIVGLSQGNMIGRALIEFCDDAPPVKSFVSIGGPHAGTASI 747
Q + C+ ++ P+L GY+ +G SQG RA+ + C PP+ + +S+GG H G +
Sbjct: 91 QVGMACQILEKDPKLQHGYNAIGFSQGGQFLRAVAQRC-PTPPMMTLISVGGQHQGVFGL 149
Query: 746 PFC--GVTWICIMLDSMIKTEIYSDYMQEHLAPSGFLKIPTDIAGYMEGCRFLPKLNNEL 573
P C + IC + + YS +QE L + + P Y FL +N E
Sbjct: 150 PRCPGESSHICDFIRKSLNAGAYSKVVQERLVQAQYWHDPIKEEVYRNCSIFLADINQER 209
Query: 572 PVKNSTYKERFSSLENLVLIMFEHDTILIPKETSWFGYYPDGSFKTILPPQETKLYTEDW 393
+ N +YKE +L+ V++ F +D+I+ P ++ WFG+Y G K +P QET LYTED
Sbjct: 210 HI-NESYKENLMALKKFVMVKFFNDSIVDPVDSEWFGFYRSGQAKETIPLQETTLYTEDR 268
Query: 392 IGLRALDEAGKVKFVNVSGNHLQISHEDMKKHIVPYL 282
+GL+ +D+AGK+ F+ G+HLQIS E HI+P+L
Sbjct: 269 LGLKKMDKAGKLVFLAKEGDHLQISKEWFTAHIIPFL 305
>sp|O88531|PPT1_MOUSE Palmitoyl-protein thioesterase 1 OS=Mus musculus GN=Ppt1
PE=2 SV=2
Length = 306
Score = 148 bits (372), Expect = 1e-034
Identities = 78/217 (35%), Positives = 123/217 (56%), Gaps = 4/217 (1%)
Frame = -3
Query: 926 QTAVVCEKVKSMPELSDGYSIVGLSQGNMIGRALIEFCDDAPPVKSFVSIGGPHAGTASI 747
Q +VC+ ++ P+L GY+ +G SQG RA+ + C PP+ + +S+GG H G +
Sbjct: 91 QVNMVCQILEKDPKLQQGYNAIGFSQGGQFLRAVAQRC-PTPPMMTLISVGGQHQGVFGL 149
Query: 746 PFC--GVTWICIMLDSMIKTEIYSDYMQEHLAPSGFLKIPTDIAGYMEGCRFLPKLNNEL 573
P C + IC + + YS +QE L + + P + Y FL +N E
Sbjct: 150 PRCPGESSHICDFIRKSLNAGAYSKLVQERLVQAQYWHDPIKESVYRNYSIFLADINQER 209
Query: 572 PVKNSTYKERFSSLENLVLIMFEHDTILIPKETSWFGYYPDGSFKTILPPQETKLYTEDW 393
V N +YK+ +L+ V++ F +D+I+ P ++ WFG+Y G K +P QE+ LYTED
Sbjct: 210 CV-NESYKKNLMALKKFVMVKFFNDSIVDPVDSEWFGFYRSGQAKETIPLQESTLYTEDR 268
Query: 392 IGLRALDEAGKVKFVNVSGNHLQISHEDMKKHIVPYL 282
+GL+ +D+AGK+ F+ G+HLQIS E HI+P+L
Sbjct: 269 LGLKKMDKAGKLVFLAKEGDHLQISKEWFTAHIIPFL 305
>sp|O59747|PDF1_SCHPO Palmitoyl-protein thioesterase-dolichyl pyrophosphate
phosphatase fusion 1 OS=Schizosaccharomyces pombe GN=pdf1 PE=1 SV=1
Length = 603
Score = 125 bits (312), Expect = 1e-027
Identities = 78/280 (27%), Positives = 147/280 (52%), Gaps = 11/280 (3%)
Frame = -3
Query: 1091 ASSVPFIVLHGIGDKCSNSGVKHFTELLSDWSSSQGYCLEIGSGSWD----SWTMPLLDQ 924
+ +P ++ HG+GD ++ + ++ + + Y + +G ++ + L DQ
Sbjct: 23 SEQLPVVIWHGLGDTPTSFTLTEVSQRVQKLTKGAVYAIRVGDNEFEDIKAGYLGKLEDQ 82
Query: 923 TAVVCEKVKSMPELSDGYSIVGLSQGNMIGRALIEFCDDAPPVKSFVSIGGPHAGTASIP 744
VC+ + + LS+G+ +GLSQG + RAL + C DA ++S +++G PH+G +IP
Sbjct: 83 LDEVCDLIGNEDSLSNGFYALGLSQGGLFLRALAQTC-DAAKIRSLITLGSPHSGINTIP 141
Query: 743 FCGVT-WIC-IMLDSMIKTEIYSDYMQEHLAPSGFLKIPTDIAGYMEGCRFLPKLNNELP 570
C T IC ++ S++ I+ ++Q H+ + + + Y+E +FL LNNE+
Sbjct: 142 GCSPTNLICKAVVHSILGLGIWHSWIQNHVVQAQYYRTEKQYDKYLENNKFLTHLNNEVL 201
Query: 569 VKNSTYK-ERFSSLENLVLIMFEHDTILIPKETSWFGYYPDGSFKTILPPQETKLYTEDW 393
N T E+ L+NLV + FE D I+ P ++ FG+ + + + I ++ LY +
Sbjct: 202 HDNYTRNIEKLKELDNLVAVSFERDDIVEPPYSTGFGWINETTGENI-EMEDFVLY--ES 258
Query: 392 IGLRALDEAGKVKFVNVSGNHLQISHEDMKKHIVPYLSDK 273
+GL+ L GK++ ++ G HLQ+ D ++ Y D+
Sbjct: 259 LGLKDLVNQGKLETISFPGRHLQMRWGDFDALVLKYFKDE 298
>sp|Q9VKH6|PPT2_DROME Lysosomal thioesterase PPT2 homolog OS=Drosophila
melanogaster GN=Ppt2 PE=2 SV=1
Length = 288
Score = 89 bits (220), Expect = 5e-017
Identities = 76/271 (28%), Positives = 126/271 (46%), Gaps = 25/271 (9%)
Frame = -3
Query: 1130 ITIIALICTFITVASSV-PFIVLHGIGDKCSNSGVKHFTELLSDWSSSQGYCLEIGSGSW 954
+ + L C+ I+V+ + P ++LHGI SG + L+ + + +
Sbjct: 7 VLVALLTCSSISVSLAYKPVVILHGI-----LSGAESMASLVREIEEFHPGTIVYNCDKF 61
Query: 953 DSW-----TMPLLDQTAVVCEKV-KSMPELSDGYSIVGLSQGNMIGRALIEFCDDAPPVK 792
+ W +DQ +V K PE G ++G SQG ++ RA I+ + VK
Sbjct: 62 NGWYSLENAWRQVDQVRDYLNEVGKLHPE---GIIVLGYSQGGLLARAAIQSLPE-HNVK 117
Query: 791 SFVSIGGPHAGTASIPFCGVTWICIMLDSMIKT--EIYSDYMQEHLAPSGFLKIPTDIAG 618
+F+S+ P AG F + I D KT E++ + +H + G+ P
Sbjct: 118 TFISLSSPQAGQYGTSFLHL----IFPDLAAKTAFELFYSRVGQHTSVGGYWNDPQRQDL 173
Query: 617 YMEGCRFLPKLNNELPVKNST-YKERFSSLENLVLIMFEHDTILIPKETSWFGYYPDGSF 441
Y++ FLP +NNE NST +K L LV+I +D ++ P ++S FGY+ +
Sbjct: 174 YLKYSEFLPLINNEKKTSNSTSFKMGMVRLNKLVMIGGPNDDVITPWQSSHFGYFDEN-- 231
Query: 440 KTILPPQETKLYTEDWIGLRALDEAGKVKFV 348
++P ++T D IG+R L EAGK+ V
Sbjct: 232 MDVIPFIRRPIFTSDSIGIRTLQEAGKLIIV 262
>sp|Q6GNY7|PPT2B_XENLA Lysosomal thioesterase PPT2-B OS=Xenopus laevis GN=ppt2-b
PE=2 SV=1
Length = 288
Score = 75 bits (183), Expect = 9e-013
Identities = 53/181 (29%), Positives = 94/181 (51%), Gaps = 5/181 (2%)
Frame = -3
Query: 875 GYSIVGLSQGNMIGRALIEFCDDAPPVKSFVSIGGPHAGTASIPFCGVTWICIMLDSMIK 696
G ++ SQG +I R L+E + V +F+++ P G + + ++ S ++
Sbjct: 90 GVHLICYSQGGLICRGLLETMPE-HNVDTFIALSSPLMGQYGMTLYVQKALPLVNISALQ 148
Query: 695 TEIYSDYMQEHLAPSGFLKIPTDIAGYMEGCRFLPKLNNELPVKNSTYKER-FSSLENLV 519
Y + +E ++ G+ + P Y+E FLPKLNNEL NST ++R F L LV
Sbjct: 149 EVCYRKFFKE-ISICGYWRDPHRYEKYLEYSAFLPKLNNELLDSNSTERKRNFLRLRKLV 207
Query: 518 LIMFEHDTILIPKETSWFGYYPDGSFKTILPPQETKLYTEDWIGLRALDEAGKVKFVNVS 339
LI D ++ P ++S FG+Y + + ++ ++ +Y +D GL++LD G + +V
Sbjct: 208 LIGGPDDEVIAPWQSSHFGFYNEK--EEVVNMKDQMVYQKDTFGLQSLDGRGAITIYSVP 265
Query: 338 G 336
G
Sbjct: 266 G 266
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,106,165,710
Number of Sequences: 518415
Number of Extensions: 6106165710
Number of Successful Extensions: 55409465
Number of sequences better than 0.0: 0
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