BLASTX 7.6.2
Query= UN01416 /QuerySize=1434
(1433 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9P0L0|VAPA_HUMAN Vesicle-associated membrane protein-associa... 84 2e-015
sp|Q5R601|VAPA_PONAB Vesicle-associated membrane protein-associa... 84 2e-015
sp|Q10484|YDFC_SCHPO Uncharacterized protein C17C9.12 OS=Schizos... 84 3e-015
sp|P40075|SCS2_YEAST Vesicle-associated membrane protein-associa... 83 4e-015
sp|A5GFS8|VAPB_PIG Vesicle-associated membrane protein-associate... 83 4e-015
sp|A2VDZ9|VAPB_BOVIN Vesicle-associated membrane protein-associa... 82 7e-015
sp|O95292|VAPB_HUMAN Vesicle-associated membrane protein-associa... 82 7e-015
sp|Q9Z269|VAPB_RAT Vesicle-associated membrane protein-associate... 82 7e-015
sp|Q9Z270|VAPA_RAT Vesicle-associated membrane protein-associate... 81 1e-014
sp|Q9QY76|VAPB_MOUSE Vesicle-associated membrane protein-associa... 81 1e-014
sp|Q9WV55|VAPA_MOUSE Vesicle-associated membrane protein-associa... 81 2e-014
sp|Q0VCY1|VAPA_BOVIN Vesicle-associated membrane protein-associa... 80 4e-014
sp|O60119|YH75_SCHPO Vesicle-associated membrane protein-associa... 78 1e-013
sp|Q16943|VP33_APLCA Vesicle-associated membrane protein/synapto... 75 8e-013
sp|Q6Q595|SCS22_YEAST Vesicle-associated membrane protein-associ... 61 2e-008
>sp|Q9P0L0|VAPA_HUMAN Vesicle-associated membrane protein-associated protein A
OS=Homo sapiens GN=VAPA PE=1 SV=3
Length = 249
Score = 84 bits (207), Expect = 2e-015
Identities = 44/128 (34%), Positives = 78/128 (60%), Gaps = 4/128 (3%)
Frame = +2
Query: 113 PRTLKFPVDLKKQTTCMVQLTNTTDRYVAFKVKTTSPKKYCVRSNVGVVAPNSSCEFSVI 292
P LKF T ++L N +DR V FKVKTT+P++YCVR N G++ P S+ SV+
Sbjct: 20 PTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPGSTVTVSVM 79
Query: 293 MQAFKEPPPDLACKDKFLIQSTAVPADTTDEDITASMFSKAEGKHIEENKLRVTLVMPSD 472
+Q F P + + K KF++Q+ P +T+D + +++ +A+ + ++KLR MP++
Sbjct: 80 LQPFDYDPNEKS-KHKFMVQTIFAPPNTSDME---AVWKEAKPDELMDSKLRCVFEMPNE 135
Query: 473 SPELSPVK 496
+ +L+ ++
Sbjct: 136 NDKLNDME 143
>sp|Q5R601|VAPA_PONAB Vesicle-associated membrane protein-associated protein A
OS=Pongo abelii GN=VAPA PE=2 SV=2
Length = 249
Score = 84 bits (207), Expect = 2e-015
Identities = 44/128 (34%), Positives = 78/128 (60%), Gaps = 4/128 (3%)
Frame = +2
Query: 113 PRTLKFPVDLKKQTTCMVQLTNTTDRYVAFKVKTTSPKKYCVRSNVGVVAPNSSCEFSVI 292
P LKF T ++L N +DR V FKVKTT+P++YCVR N G++ P S+ SV+
Sbjct: 20 PTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPGSTVTVSVM 79
Query: 293 MQAFKEPPPDLACKDKFLIQSTAVPADTTDEDITASMFSKAEGKHIEENKLRVTLVMPSD 472
+Q F P + + K KF++Q+ P +T+D + +++ +A+ + ++KLR MP++
Sbjct: 80 LQPFDYDPNEKS-KHKFMVQTIFAPPNTSDME---AVWKEAKPDELMDSKLRCVFEMPNE 135
Query: 473 SPELSPVK 496
+ +L+ ++
Sbjct: 136 NDKLNDME 143
>sp|Q10484|YDFC_SCHPO Uncharacterized protein C17C9.12 OS=Schizosaccharomyces
pombe GN=SPAC17C9.12 PE=1 SV=2
Length = 319
Score = 84 bits (205), Expect = 3e-015
Identities = 45/111 (40%), Positives = 65/111 (58%), Gaps = 2/111 (1%)
Frame = +2
Query: 119 TLKFPVDLKKQTTCMVQLTNTTDRYVAFKVKTTSPKKYCVRSNVGVVAPNSSCEFSVIMQ 298
T+ FP L + C ++L NT + FKVKTT+PK+YCVR N G + NS+ VI+Q
Sbjct: 8 TIVFPRPLTRLVKCDLELRNTAPYPIGFKVKTTAPKQYCVRPNGGRIEANSAVSVEVILQ 67
Query: 299 AF-KEPPPDLACKDKFLIQSTAVPADTTDEDITASMFSKAEGKHIEENKLR 448
EP P C+DKFL+QST + + DI A ++++ +I E K+R
Sbjct: 68 PLDHEPAPGTKCRDKFLVQSTELKPELQGMDI-ADIWTQVSKANISERKIR 117
>sp|P40075|SCS2_YEAST Vesicle-associated membrane protein-associated protein
SCS2 OS=Saccharomyces cerevisiae GN=SCS2 PE=1 SV=3
Length = 244
Score = 83 bits (204), Expect = 4e-015
Identities = 52/175 (29%), Positives = 91/175 (52%), Gaps = 6/175 (3%)
Frame = +2
Query: 92 MPLLDIQPRTLKFPVDLKKQTTCMVQLTNTTDRYVAFKVKTTSPKKYCVRSNVGVVAPNS 271
M ++I P L + L +Q+T ++N +D+ +AFKVKTT+PK YCVR N VVAP
Sbjct: 1 MSAVEISPDVLVYKSPLTEQSTEYASISNNSDQTIAFKVKTTAPKFYCVRPNAAVVAPGE 60
Query: 272 SCEFSVIMQAF-KEPPPDLACKDKFLIQSTAVPADTTDEDITASMFSKAEGKHIEENKLR 448
+ + VI +EP D C+DKFL+ + P D + + A ++S E + ++ +
Sbjct: 61 TIQVQVIFLGLTEEPAADFKCRDKFLVITLPSPYDLNGKAV-ADVWSDLEAEFKQQAISK 119
Query: 449 VTLVMPSDSPELSPVKG-TLKQEAVFEDSILKDGLYGQSETLPPPQYESEIVKEP 610
V SP++ P + +++ + +++D + + +P E E+ EP
Sbjct: 120 KIKVKYLISPDVHPAQNQNIQENKETVEPVVQD---SEPKEVPAVVNEKEVPAEP 171
>sp|A5GFS8|VAPB_PIG Vesicle-associated membrane protein-associated protein B
OS=Sus scrofa GN=VAPB PE=3 SV=1
Length = 243
Score = 83 bits (204), Expect = 4e-015
Identities = 46/127 (36%), Positives = 78/127 (61%), Gaps = 5/127 (3%)
Frame = +2
Query: 98 LLDIQPR-TLKFPVDLKKQTTCMVQLTNTTDRYVAFKVKTTSPKKYCVRSNVGVVAPNSS 274
+L ++P+ LKF T ++L N TDR V FKVKTT+P++YCVR N G++ +S
Sbjct: 7 VLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGAS 66
Query: 275 CEFSVIMQAFKEPPPDLACKDKFLIQSTAVPADTTDEDITASMFSKAEGKHIEENKLRVT 454
SV++Q F P + + K KF++QS PADT+D + + + +A+ + + ++KLR
Sbjct: 67 INVSVMLQPFDYDPNEKS-KHKFMVQSMFAPADTSDME---AAWKEAKPEDLMDSKLRCV 122
Query: 455 LVMPSDS 475
+P+++
Sbjct: 123 FELPAEN 129
>sp|A2VDZ9|VAPB_BOVIN Vesicle-associated membrane protein-associated protein B
OS=Bos taurus GN=VAPB PE=2 SV=1
Length = 243
Score = 82 bits (202), Expect = 7e-015
Identities = 45/127 (35%), Positives = 78/127 (61%), Gaps = 5/127 (3%)
Frame = +2
Query: 98 LLDIQPR-TLKFPVDLKKQTTCMVQLTNTTDRYVAFKVKTTSPKKYCVRSNVGVVAPNSS 274
+L ++P+ LKF T ++L N TDR V FKVKTT+P++YCVR N G++ +S
Sbjct: 7 VLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGAS 66
Query: 275 CEFSVIMQAFKEPPPDLACKDKFLIQSTAVPADTTDEDITASMFSKAEGKHIEENKLRVT 454
SV++Q F P + + K KF++QS P DT+D + +++ +A+ + + ++KLR
Sbjct: 67 INVSVMLQPFDYDPNEKS-KHKFMVQSMFAPTDTSDME---AVWKEAKPEDLMDSKLRCV 122
Query: 455 LVMPSDS 475
+P+++
Sbjct: 123 FELPAEN 129
>sp|O95292|VAPB_HUMAN Vesicle-associated membrane protein-associated protein B/C
OS=Homo sapiens GN=VAPB PE=1 SV=3
Length = 243
Score = 82 bits (202), Expect = 7e-015
Identities = 45/127 (35%), Positives = 78/127 (61%), Gaps = 5/127 (3%)
Frame = +2
Query: 98 LLDIQPR-TLKFPVDLKKQTTCMVQLTNTTDRYVAFKVKTTSPKKYCVRSNVGVVAPNSS 274
+L ++P+ LKF T ++L N TDR V FKVKTT+P++YCVR N G++ +S
Sbjct: 7 VLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGAS 66
Query: 275 CEFSVIMQAFKEPPPDLACKDKFLIQSTAVPADTTDEDITASMFSKAEGKHIEENKLRVT 454
SV++Q F P + + K KF++QS P DT+D + +++ +A+ + + ++KLR
Sbjct: 67 INVSVMLQPFDYDPNEKS-KHKFMVQSMFAPTDTSDME---AVWKEAKPEDLMDSKLRCV 122
Query: 455 LVMPSDS 475
+P+++
Sbjct: 123 FELPAEN 129
>sp|Q9Z269|VAPB_RAT Vesicle-associated membrane protein-associated protein B
OS=Rattus norvegicus GN=Vapb PE=1 SV=3
Length = 243
Score = 82 bits (202), Expect = 7e-015
Identities = 46/127 (36%), Positives = 78/127 (61%), Gaps = 5/127 (3%)
Frame = +2
Query: 98 LLDIQPR-TLKFPVDLKKQTTCMVQLTNTTDRYVAFKVKTTSPKKYCVRSNVGVVAPNSS 274
+L ++P+ LKF T ++L N TDR V FKVKTT+P++YCVR N GV+ +S
Sbjct: 7 VLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGVIDAGAS 66
Query: 275 CEFSVIMQAFKEPPPDLACKDKFLIQSTAVPADTTDEDITASMFSKAEGKHIEENKLRVT 454
SV++Q F P + + K KF++QS P DT+D + +++ +A+ + + ++KLR
Sbjct: 67 LNVSVMLQPFDYDPNEKS-KHKFMVQSMFAPPDTSDME---AVWKEAKPEDLMDSKLRCV 122
Query: 455 LVMPSDS 475
+P+++
Sbjct: 123 FELPAEN 129
>sp|Q9Z270|VAPA_RAT Vesicle-associated membrane protein-associated protein A
OS=Rattus norvegicus GN=Vapa PE=1 SV=3
Length = 249
Score = 81 bits (199), Expect = 1e-014
Identities = 44/128 (34%), Positives = 76/128 (59%), Gaps = 4/128 (3%)
Frame = +2
Query: 113 PRTLKFPVDLKKQTTCMVQLTNTTDRYVAFKVKTTSPKKYCVRSNVGVVAPNSSCEFSVI 292
P LKF T ++L N +DR V FKVKTT+P++YCVR N GV+ P S SV+
Sbjct: 20 PSDLKFKGPFTDVVTTNLKLQNPSDRKVCFKVKTTAPRRYCVRPNSGVIDPGSIVTVSVM 79
Query: 293 MQAFKEPPPDLACKDKFLIQSTAVPADTTDEDITASMFSKAEGKHIEENKLRVTLVMPSD 472
+Q F P + + K KF++Q+ P + +D + +++ +A+ + ++KLR MP++
Sbjct: 80 LQPFDYDPNEKS-KHKFMVQTIFAPPNISDME---AVWKEAKPDELMDSKLRCVFEMPNE 135
Query: 473 SPELSPVK 496
+ +L+ ++
Sbjct: 136 NDKLNDME 143
>sp|Q9QY76|VAPB_MOUSE Vesicle-associated membrane protein-associated protein B
OS=Mus musculus GN=Vapb PE=2 SV=3
Length = 243
Score = 81 bits (199), Expect = 1e-014
Identities = 46/127 (36%), Positives = 77/127 (60%), Gaps = 5/127 (3%)
Frame = +2
Query: 98 LLDIQPR-TLKFPVDLKKQTTCMVQLTNTTDRYVAFKVKTTSPKKYCVRSNVGVVAPNSS 274
+L ++P+ LKF T ++L N TDR V FKVKTT P++YCVR N GV+ +S
Sbjct: 7 VLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTVPRRYCVRPNSGVIDAGAS 66
Query: 275 CEFSVIMQAFKEPPPDLACKDKFLIQSTAVPADTTDEDITASMFSKAEGKHIEENKLRVT 454
SV++Q F P + + K KF++QS P DT+D + +++ +A+ + + ++KLR
Sbjct: 67 LNVSVMLQPFDYDPNEKS-KHKFMVQSMFAPPDTSDME---AVWKEAKPEDLMDSKLRCV 122
Query: 455 LVMPSDS 475
+P+++
Sbjct: 123 FELPAEN 129
>sp|Q9WV55|VAPA_MOUSE Vesicle-associated membrane protein-associated protein A
OS=Mus musculus GN=Vapa PE=1 SV=2
Length = 249
Score = 81 bits (198), Expect = 2e-014
Identities = 43/128 (33%), Positives = 76/128 (59%), Gaps = 4/128 (3%)
Frame = +2
Query: 113 PRTLKFPVDLKKQTTCMVQLTNTTDRYVAFKVKTTSPKKYCVRSNVGVVAPNSSCEFSVI 292
P LKF T ++L N +DR V FKVKTT+P++YCVR N G++ P S SV+
Sbjct: 20 PSDLKFKGPFTDVVTTNLKLQNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPGSIVTVSVM 79
Query: 293 MQAFKEPPPDLACKDKFLIQSTAVPADTTDEDITASMFSKAEGKHIEENKLRVTLVMPSD 472
+Q F P + + K KF++Q+ P + +D + +++ +A+ + ++KLR MP++
Sbjct: 80 LQPFDYDPNEKS-KHKFMVQTIFAPPNISDME---AVWKEAKPDELMDSKLRCVFEMPNE 135
Query: 473 SPELSPVK 496
+ +L+ ++
Sbjct: 136 NDKLNDME 143
>sp|Q0VCY1|VAPA_BOVIN Vesicle-associated membrane protein-associated protein A
OS=Bos taurus GN=VAPA PE=2 SV=1
Length = 249
Score = 80 bits (195), Expect = 4e-014
Identities = 42/128 (32%), Positives = 76/128 (59%), Gaps = 4/128 (3%)
Frame = +2
Query: 113 PRTLKFPVDLKKQTTCMVQLTNTTDRYVAFKVKTTSPKKYCVRSNVGVVAPNSSCEFSVI 292
P LKF T ++L N +DR V FKVKTT+P++YCVR N G++ P + SV+
Sbjct: 20 PTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPGLTVTVSVM 79
Query: 293 MQAFKEPPPDLACKDKFLIQSTAVPADTTDEDITASMFSKAEGKHIEENKLRVTLVMPSD 472
+Q F P + + K KF++Q+ P + +D + +++ +A+ + ++KLR MP++
Sbjct: 80 LQPFDYDPNEKS-KHKFMVQTIFAPPNISDME---AVWKEAKPDELMDSKLRCVFEMPNE 135
Query: 473 SPELSPVK 496
+ +L+ ++
Sbjct: 136 NDKLNDME 143
>sp|O60119|YH75_SCHPO Vesicle-associated membrane protein-associated protein
C16G5.05c OS=Schizosaccharomyces pombe GN=SPBC16G5.05c PE=1 SV=1
Length = 383
Score = 78 bits (191), Expect = 1e-013
Identities = 43/100 (43%), Positives = 62/100 (62%), Gaps = 4/100 (4%)
Frame = +2
Query: 161 MVQLTNTTDRYVAFKVKTTSPKKYCVRSNVGVVAPNSSCEFSVIMQAFK-EPPPDLACKD 337
++ + N V FKVKTT+PK YCVR N G + P S+ V++QA K EP PD C+D
Sbjct: 22 LISVHNPNPEPVIFKVKTTAPKHYCVRPNSGKIEPKSTVNVQVLLQAMKEEPAPDFKCRD 81
Query: 338 KFLIQSTAV-PADTTDEDITASMFSKAE--GKHIEENKLR 448
KFLIQS A+ ADT++ + +++ E G+ I + K+R
Sbjct: 82 KFLIQSMAIGDADTSNVENYHEFWTEMEKQGRSIFDRKIR 121
>sp|Q16943|VP33_APLCA Vesicle-associated membrane protein/synaptobrevin-binding
protein OS=Aplysia californica PE=2 SV=1
Length = 260
Score = 75 bits (184), Expect = 8e-013
Identities = 48/151 (31%), Positives = 74/151 (49%), Gaps = 5/151 (3%)
Frame = +2
Query: 122 LKFPVDLKKQTTCMVQLTNTTDRYVAFKVKTTSPKKYCVRSNVGVVAPNSSCEFSVIMQA 301
L+F T ++L+N TDR + FKVKTT+PK+YCVR N G++ P +S +V++Q
Sbjct: 16 LRFKGPFTDVVTADLKLSNPTDRRICFKVKTTAPKRYCVRPNSGILEPKTSIAVAVMLQP 75
Query: 302 FKEPPPDLACKDKFLIQSTAVPADTTDEDITASMFSKAEGKHIEENKLRVTLVMPSDSPE 481
F P + K KF++QS P + ++ A + + + KLR MP S +
Sbjct: 76 FNYDPNE-KNKHKFMVQSMYAPDHVVESQ--ELLWKDAPPESLMDTKLRCVFEMPDGSHQ 132
Query: 482 --LSPVKGTLKQEAVFEDSILKDGLYGQSET 568
S A F +S L+D +T
Sbjct: 133 APASDASRATDAGAHFSESALEDPTVASRKT 163
>sp|Q6Q595|SCS22_YEAST Vesicle-associated membrane protein-associated protein
SCS22 OS=Saccharomyces cerevisiae GN=SCS22 PE=1 SV=2
Length = 175
Score = 61 bits (146), Expect = 2e-008
Identities = 32/91 (35%), Positives = 49/91 (53%), Gaps = 3/91 (3%)
Frame = +2
Query: 107 IQPRTLKFPVDLKKQTTCMVQLTNTTDRYVAFKVKTTSPKKYCVRSNVGVVAPNSSCEFS 286
I P L F L KQ+T ++L N ++ V FKV+T++P KYCVR NV ++ + S
Sbjct: 3 IVPEKLVFKAPLNKQSTEYIKLENDGEKRVIFKVRTSAPTKYCVRPNVAIIGAHESVNVQ 62
Query: 287 VIMQAFKEPPPDLAC---KDKFLIQSTAVPA 370
++ + D +DKFLI + +PA
Sbjct: 63 IVFLGLPKSTADDEMDQKRDKFLIVTLPIPA 93
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,106,165,710
Number of Sequences: 518415
Number of Extensions: 6106165710
Number of Successful Extensions: 55409465
Number of sequences better than 0.0: 0
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