BLASTX 7.6.2
Query= UN01439 /QuerySize=712
(711 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53799|FDFT_ARATH Squalene synthase OS=Arabidopsis thaliana G... 224 6e-058
sp|P53800|FDFT_NICBE Squalene synthase OS=Nicotiana benthamiana ... 180 8e-045
sp|O74165|FDFT_PICJA Squalene synthase OS=Pichia jadinii GN=ERG9... 85 4e-016
sp|Q32KR6|FDFT_BOVIN Squalene synthase OS=Bos taurus GN=FDFT1 PE... 85 5e-016
sp|P53798|FDFT_MOUSE Squalene synthase OS=Mus musculus GN=Fdft1 ... 85 5e-016
sp|P37268|FDFT_HUMAN Squalene synthase OS=Homo sapiens GN=FDFT1 ... 84 6e-016
sp|Q5R6U3|FDFT_PONAB Squalene synthase OS=Pongo abelii GN=FDFT1 ... 84 6e-016
sp|Q02769|FDFT_RAT Squalene synthase OS=Rattus norvegicus GN=Fdf... 80 9e-015
sp|Q54DR1|FDFT_DICDI Squalene synthase OS=Dictyostelium discoide... 79 2e-014
sp|P78589|FDFT_CANAL Squalene synthase OS=Candida albicans GN=ER... 76 2e-013
sp|P29704|FDFT_YEAST Squalene synthase OS=Saccharomyces cerevisi... 76 2e-013
sp|Q9HGZ6|FDFT_CANGA Squalene synthase OS=Candida glabrata GN=ER... 74 8e-013
sp|Q752X9|FDFT_ASHGO Squalene synthase OS=Ashbya gossypii GN=ERG... 74 1e-012
sp|Q92459|FDFT_USTMA Squalene synthase OS=Ustilago maydis GN=ERG... 71 5e-012
sp|Q9Y753|FDFT_YARLI Squalene synthase OS=Yarrowia lipolytica GN... 69 2e-011
sp|P36596|FDFT_SCHPO Squalene synthase OS=Schizosaccharomyces po... 69 3e-011
sp|Q7S4Z6|FDFT_NEUCR Probable squalene synthase OS=Neurospora cr... 62 4e-009
>sp|P53799|FDFT_ARATH Squalene synthase OS=Arabidopsis thaliana GN=SQS1 PE=2
SV=1
Length = 410
Score = 224 bits (569), Expect = 6e-058
Identities = 105/116 (90%), Positives = 108/116 (93%)
Frame = +2
Query: 311 MGSLGTLLRYPDDIYPLLKMKRAIEKAEK*IPPEPHWGFCYSMLHKVSRSFSLFIQQLRP 490
MGSLGT+LRYPDDIYPLLKMKRAIEKAEK IPPEPHWGFCYSMLHKVSRSFSL IQQL
Sbjct: 1 MGSLGTMLRYPDDIYPLLKMKRAIEKAEKQIPPEPHWGFCYSMLHKVSRSFSLVIQQLNT 60
Query: 491 ELRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFHRHIYDTDWHYSCGTNEYK 658
ELRNAVCVFYLVL ALDTVEDDTSI TDEK+P+L AFHRHIYDTDWHYSCGT EYK
Sbjct: 61 ELRNAVCVFYLVLRALDTVEDDTSIPTDEKVPILIAFHRHIYDTDWHYSCGTKEYK 116
>sp|P53800|FDFT_NICBE Squalene synthase OS=Nicotiana benthamiana PE=2 SV=1
Length = 411
Score = 180 bits (456), Expect = 8e-045
Identities = 81/116 (69%), Positives = 98/116 (84%)
Frame = +2
Query: 311 MGSLGTLLRYPDDIYPLLKMKRAIEKAEK*IPPEPHWGFCYSMLHKVSRSFSLFIQQLRP 490
MGSL +L+ P+D+YPL+K+K A AEK IPP P+WGFCYSMLHKVSRSF+L IQQL
Sbjct: 1 MGSLRAILKNPEDLYPLVKLKLAARHAEKQIPPSPNWGFCYSMLHKVSRSFALVIQQLPV 60
Query: 491 ELRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFHRHIYDTDWHYSCGTNEYK 658
ELR+AVC+FYLVL ALDTVEDDTSI TD K+P+L +FH+H+YD +WH+SCGT EYK
Sbjct: 61 ELRDAVCIFYLVLRALDTVEDDTSIPTDVKVPILISFHQHVYDREWHFSCGTKEYK 116
>sp|O74165|FDFT_PICJA Squalene synthase OS=Pichia jadinii GN=ERG9 PE=3 SV=1
Length = 443
Score = 85 bits (209), Expect = 4e-016
Identities = 48/110 (43%), Positives = 63/110 (57%), Gaps = 2/110 (1%)
Frame = +2
Query: 311 MGSLGTLLRYPDDIYPLLKMK--RAIEKAEK*IPPEPHWGFCYSMLHKVSRSFSLFIQQL 484
MG L L +PD++ +++ K R E A CY +L+ SRSF+ I++L
Sbjct: 1 MGKLLQLALHPDELASIVQFKLFRKNENARNPATESAELIRCYELLNLTSRSFAAVIEEL 60
Query: 485 RPELRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFHRHIYDTDWHY 634
PELRN + VFYLVL ALDTVE D SI+ KLPVL FH + DW +
Sbjct: 61 HPELRNVIMVFYLVLRALDTVEVDMSIENSVKLPVLRQFHEKLDTKDWTF 110
>sp|Q32KR6|FDFT_BOVIN Squalene synthase OS=Bos taurus GN=FDFT1 PE=2 SV=1
Length = 417
Score = 85 bits (208), Expect = 5e-016
Identities = 44/108 (40%), Positives = 66/108 (61%), Gaps = 8/108 (7%)
Frame = +2
Query: 332 LRYPDDIYPLLKMKRAIEKAEK*IPPEPHWGF------CYSMLHKVSRSFSLFIQQLRPE 493
L +P++ Y LL+ + + K IP CY L++ SRSF+ IQ L E
Sbjct: 7 LGHPEEFYNLLRFQMGGRR--KVIPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQALDGE 64
Query: 494 LRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFHRHIYDTDWHYS 637
+R+AVC+FYLVL ALDT+EDD +I + K+P+L FH ++Y+ DW ++
Sbjct: 65 MRHAVCIFYLVLRALDTLEDDMTISIERKVPLLHNFHSYLYEPDWRFT 112
>sp|P53798|FDFT_MOUSE Squalene synthase OS=Mus musculus GN=Fdft1 PE=2 SV=1
Length = 416
Score = 85 bits (208), Expect = 5e-016
Identities = 37/70 (52%), Positives = 52/70 (74%)
Frame = +2
Query: 428 CYSMLHKVSRSFSLFIQQLRPELRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFHR 607
CY L++ SRSF+ IQ L ++R+A+CVFYLVL ALDTVEDD SI ++K+P+L FH
Sbjct: 43 CYKYLNQTSRSFAAVIQALDGDIRHAICVFYLVLRALDTVEDDMSISVEKKIPLLCNFHT 102
Query: 608 HIYDTDWHYS 637
+YD +W ++
Sbjct: 103 FLYDPEWRFT 112
>sp|P37268|FDFT_HUMAN Squalene synthase OS=Homo sapiens GN=FDFT1 PE=1 SV=1
Length = 417
Score = 84 bits (207), Expect = 6e-016
Identities = 37/69 (53%), Positives = 50/69 (72%)
Frame = +2
Query: 428 CYSMLHKVSRSFSLFIQQLRPELRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFHR 607
CY L++ SRSF+ IQ L E+RNAVC+FYLVL ALDT+EDD +I ++K+P+L FH
Sbjct: 43 CYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHS 102
Query: 608 HIYDTDWHY 634
+Y DW +
Sbjct: 103 FLYQPDWRF 111
>sp|Q5R6U3|FDFT_PONAB Squalene synthase OS=Pongo abelii GN=FDFT1 PE=2 SV=1
Length = 417
Score = 84 bits (207), Expect = 6e-016
Identities = 37/69 (53%), Positives = 50/69 (72%)
Frame = +2
Query: 428 CYSMLHKVSRSFSLFIQQLRPELRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFHR 607
CY L++ SRSF+ IQ L E+RNAVC+FYLVL ALDT+EDD +I ++K+P+L FH
Sbjct: 43 CYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHS 102
Query: 608 HIYDTDWHY 634
+Y DW +
Sbjct: 103 FLYQPDWRF 111
>sp|Q02769|FDFT_RAT Squalene synthase OS=Rattus norvegicus GN=Fdft1 PE=2 SV=1
Length = 416
Score = 80 bits (197), Expect = 9e-015
Identities = 38/93 (40%), Positives = 58/93 (62%)
Frame = +2
Query: 428 CYSMLHKVSRSFSLFIQQLRPELRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFHR 607
CY L + SRSF+ IQ L ++R+AVCVFYL+L A+DTVEDD +I ++K+P+L FH
Sbjct: 43 CYKYLDQTSRSFAAVIQALDGDIRHAVCVFYLILRAMDTVEDDMAISVEKKIPLLRNFHT 102
Query: 608 HIYDTDWHYSCGTNEYKF*WISFIMFLQHFWNL 706
+Y+ +W ++ +++ F F NL
Sbjct: 103 FLYEPEWRFTESKEKHRVVLEDFPTISLEFRNL 135
>sp|Q54DR1|FDFT_DICDI Squalene synthase OS=Dictyostelium discoideum GN=fdfT PE=3
SV=1
Length = 416
Score = 79 bits (194), Expect = 2e-014
Identities = 33/64 (51%), Positives = 49/64 (76%)
Frame = +2
Query: 425 FCYSMLHKVSRSFSLFIQQLRPELRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFH 604
+CY +L+K SRSF+ I +L P L++A+C+FYLVL LDT+EDDT+++ + KLPVL +F
Sbjct: 40 WCYELLNKTSRSFAFVINELEPSLKDAICIFYLVLRGLDTIEDDTTVELNTKLPVLTSFS 99
Query: 605 RHIY 616
+Y
Sbjct: 100 EGLY 103
>sp|P78589|FDFT_CANAL Squalene synthase OS=Candida albicans GN=ERG9 PE=3 SV=1
Length = 448
Score = 76 bits (186), Expect = 2e-013
Identities = 42/118 (35%), Positives = 72/118 (61%), Gaps = 5/118 (4%)
Frame = +2
Query: 311 MGSLGTLLRYPDDIYPLLKM---KRAIEKAEK*IPPEPHWGFCYSMLHKVSRSFSLFIQQ 481
MG LL +P ++ ++++ ++ + ++ + + G CY +L+ SRSF+ I++
Sbjct: 1 MGKFLQLLSHPTELKAVIQLFGFRQPLHPGKRDV-NDKELGRCYELLNLTSRSFAAVIEE 59
Query: 482 LRPELRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFHRHIYDTDWHY-SCGTNE 652
L PELR+AV +FYLVL ALDT+EDD +I++ K+P+L F + +W + G NE
Sbjct: 60 LHPELRDAVMIFYLVLRALDTIEDDMTIKSSIKIPLLREFDTKLNTKNWTFDGYGPNE 117
>sp|P29704|FDFT_YEAST Squalene synthase OS=Saccharomyces cerevisiae GN=ERG9 PE=1
SV=2
Length = 444
Score = 76 bits (186), Expect = 2e-013
Identities = 45/118 (38%), Positives = 66/118 (55%), Gaps = 2/118 (1%)
Frame = +2
Query: 311 MGSLGTLLRYPDDIYPLLKMK--RAIEKAEK*IPPEPHWGFCYSMLHKVSRSFSLFIQQL 484
MG L L +P ++ LK+K R + P+ C+ +L+ SRSF+ I++L
Sbjct: 1 MGKLLQLALHPVEMKAALKLKFCRTPLFSIYDQSTSPYLLHCFELLNLTSRSFAAVIREL 60
Query: 485 RPELRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFHRHIYDTDWHYSCGTNEYK 658
PELRN V +FYL+L ALDT+EDD SI+ D K+ +L FH + T W + + K
Sbjct: 61 HPELRNCVTLFYLILRALDTIEDDMSIEHDLKIDLLRHFHEKLLLTKWSFDGNAPDVK 118
>sp|Q9HGZ6|FDFT_CANGA Squalene synthase OS=Candida glabrata GN=ERG9 PE=3 SV=2
Length = 443
Score = 74 bits (180), Expect = 8e-013
Identities = 44/110 (40%), Positives = 60/110 (54%), Gaps = 2/110 (1%)
Frame = +2
Query: 311 MGSLGTLLRYPDDIYPLLKMK--RAIEKAEK*IPPEPHWGFCYSMLHKVSRSFSLFIQQL 484
MG + L +P ++ LK+K R + P CY +L+ SRSF+ I +L
Sbjct: 1 MGKVLDLALHPLELRAALKLKFIRQPLFSTNDTRATPQLERCYELLNLTSRSFAAVIMEL 60
Query: 485 RPELRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFHRHIYDTDWHY 634
PELRN + VFYL+L ALDTVEDD +I K+ VL F + TDW +
Sbjct: 61 HPELRNVIMVFYLILRALDTVEDDMTIDPQLKVKVLREFDSKLDTTDWSF 110
>sp|Q752X9|FDFT_ASHGO Squalene synthase OS=Ashbya gossypii GN=ERG9 PE=3 SV=1
Length = 441
Score = 74 bits (179), Expect = 1e-012
Identities = 44/113 (38%), Positives = 62/113 (54%), Gaps = 8/113 (7%)
Frame = +2
Query: 311 MGSLGTLLRYPDDIYPLLKMKRAIEKAEK*IPPEPHWGF-----CYSMLHKVSRSFSLFI 475
MG + L +P ++ LK+K E P + G CY +L + SRSF+ I
Sbjct: 1 MGKVVQLFTHPLELKAALKLKFLREPL---YPADDTQGSAELKRCYQLLQRTSRSFAAVI 57
Query: 476 QQLRPELRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFHRHIYDTDWHY 634
+L PELRNAV +FYL+L ALDTVEDD +I K+P+L F + + W +
Sbjct: 58 MELHPELRNAVMLFYLILRALDTVEDDMTISPKVKVPLLREFDQKLKLDTWSF 110
>sp|Q92459|FDFT_USTMA Squalene synthase OS=Ustilago maydis GN=ERG9 PE=3 SV=2
Length = 572
Score = 71 bits (173), Expect = 5e-012
Identities = 33/76 (43%), Positives = 50/76 (65%), Gaps = 1/76 (1%)
Frame = +2
Query: 428 CYSMLHKVSRSFSLFIQQLRPELRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFHR 607
C+ L SRSF+ I++L+ EL +C+FYLVL ALDTVEDD +I K+P+L F++
Sbjct: 50 CWGFLDLTSRSFAAVIKELKGELSRVICLFYLVLRALDTVEDDMTIPAQRKIPLLVNFYK 109
Query: 608 HIYDTDWHYS-CGTNE 652
++ W+++ G NE
Sbjct: 110 YLEQPGWNFTESGPNE 125
>sp|Q9Y753|FDFT_YARLI Squalene synthase OS=Yarrowia lipolytica GN=SQS1 PE=3
SV=1
Length = 445
Score = 69 bits (168), Expect = 2e-011
Identities = 31/70 (44%), Positives = 48/70 (68%)
Frame = +2
Query: 428 CYSMLHKVSRSFSLFIQQLRPELRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFHR 607
CY +L SRSF+ I++L PE+R+AV +FYL+L ALDT+EDD ++ D K+P+L F +
Sbjct: 42 CYELLDVCSRSFAAVIRELHPEVRDAVMLFYLILRALDTIEDDMTLSRDIKIPILRDFTK 101
Query: 608 HIYDTDWHYS 637
+ W ++
Sbjct: 102 CMKTPGWKFT 111
>sp|P36596|FDFT_SCHPO Squalene synthase OS=Schizosaccharomyces pombe GN=erg9
PE=1 SV=1
Length = 460
Score = 69 bits (167), Expect = 3e-011
Identities = 35/76 (46%), Positives = 50/76 (65%), Gaps = 1/76 (1%)
Frame = +2
Query: 428 CYSMLHKVSRSFSLFIQQLRPELRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFHR 607
CY +L SRSF++ I++L +R AV +FYLVL LDTVEDD ++ D+KLP+L F++
Sbjct: 38 CYQLLDMTSRSFAVVIKELPNGIREAVMIFYLVLRGLDTVEDDMTLPLDKKLPILRDFYK 97
Query: 608 HIYDTDWHYS-CGTNE 652
I W ++ G NE
Sbjct: 98 TIEVEGWTFNESGPNE 113
>sp|Q7S4Z6|FDFT_NEUCR Probable squalene synthase OS=Neurospora crassa GN=erg-9
PE=3 SV=1
Length = 481
Score = 62 bits (148), Expect = 4e-009
Identities = 34/76 (44%), Positives = 45/76 (59%), Gaps = 1/76 (1%)
Frame = +2
Query: 428 CYSMLHKVSRSFSLFIQQLRPELRNAVCVFYLVLLALDTVEDDTSIQTDEKLPVLFAFHR 607
C+ L SRSFS IQ+L PEL +C+FYLVL LDT+EDD +I +K P+L F
Sbjct: 45 CFRHLELTSRSFSAVIQELNPELLMPICLFYLVLRGLDTIEDDMTIDLAKKEPLLREFAD 104
Query: 608 HIYDTDWHYS-CGTNE 652
+ W ++ G NE
Sbjct: 105 LMEIDGWTFTENGPNE 120
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,106,165,710
Number of Sequences: 518415
Number of Extensions: 6106165710
Number of Successful Extensions: 55409465
Number of sequences better than 0.0: 0
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