BLASTX 7.6.2
Query= UN02049 /QuerySize=1356
(1355 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q3SWX0|NIPA2_BOVIN Magnesium transporter NIPA2 OS=Bos taurus ... 303 3e-081
sp|Q8N8Q9|NIPA2_HUMAN Magnesium transporter NIPA2 OS=Homo sapien... 302 6e-081
sp|Q5R7Q3|NIPA2_PONAB Magnesium transporter NIPA2 OS=Pongo abeli... 302 6e-081
sp|Q5RDB8|NIPA3_PONAB Magnesium transporter NIPA3 OS=Pongo abeli... 296 3e-079
sp|Q6NVV3|NIPA3_HUMAN Magnesium transporter NIPA3 OS=Homo sapien... 295 6e-079
sp|Q9JJC8|NIPA2_MOUSE Magnesium transporter NIPA2 OS=Mus musculu... 293 2e-078
sp|Q8BMW7|NIPA3_MOUSE Magnesium transporter NIPA3 OS=Mus musculu... 288 7e-077
sp|Q0D2K0|NIPA4_HUMAN Magnesium transporter NIPA4 OS=Homo sapien... 283 3e-075
sp|Q8BZF2|NIPA4_MOUSE Magnesium transporter NIPA4 OS=Mus musculu... 280 2e-074
sp|Q7RTP0|NIPA1_HUMAN Magnesium transporter NIPA1 OS=Homo sapien... 209 6e-053
sp|Q8BHK1|NIPA1_MOUSE Magnesium transporter NIPA1 OS=Mus musculu... 209 6e-053
sp|Q5RD30|NPAL3_PONAB NIPA-like protein 3 OS=Pongo abelii GN=NIP... 136 4e-031
sp|Q6P499|NPAL3_HUMAN NIPA-like protein 3 OS=Homo sapiens GN=NIP... 136 6e-031
sp|Q9H841|NPAL2_HUMAN NIPA-like protein 2 OS=Homo sapiens GN=NIP... 131 2e-029
sp|Q8BGN5|NPAL3_MOUSE NIPA-like protein 3 OS=Mus musculus GN=Nip... 127 2e-028
sp|Q91WC7|NPAL2_MOUSE NIPA-like protein 2 OS=Mus musculus GN=Nip... 123 3e-027
>sp|Q3SWX0|NIPA2_BOVIN Magnesium transporter NIPA2 OS=Bos taurus GN=NIPA2 PE=2
SV=1
Length = 360
Score = 303 bits (774), Expect = 3e-081
Identities = 154/304 (50%), Positives = 215/304 (70%), Gaps = 2/304 (0%)
Frame = +3
Query: 255 GLVLAISSSLFIGASFIVKKKGLKKAGATG-TRAGVGGYSYLYEPLWWIGVTTMLLGEIA 431
GL LA+SSS+FIG SFI+KKKGL + G TRAG GG++YL E LWW G+ +M GE+A
Sbjct: 13 GLGLAMSSSIFIGGSFILKKKGLLRLARKGSTRAGQGGHAYLKEWLWWAGLLSMGAGEVA 72
Query: 432 NFAAYAFAPAILVTPLGALSIIISAVLAHIILLEKLHIFGVLGCALCVVGSTTIVLHAPQ 611
NFAAYAFAPA LVTPLGALS+++SA+L+ L E+L++ G +GC L ++GST +V+HAP+
Sbjct: 73 NFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPK 132
Query: 612 EQEIGSVLEVWNLATEPAFMFYASLIIGAAVFLIIRYVPQYGQTNVMVYIGICSLVGSLS 791
E+EI ++ E+ + +P F+ +A+L++ ++ LI P++GQTN++VYI ICS++G++S
Sbjct: 133 EEEIETLNEMSHKLGDPGFVVFATLVVIVSLILIFVVGPRHGQTNILVYITICSVIGAVS 192
Query: 792 VMSVKALGIALKLTFSGTNQLFYPQTWVFTLVVLTCVITQLNYLNKALDTFNTAIVSPIY 971
V K LGIA+K F+G L +P TW+ L ++ CV TQ+NYLN+ALD FNT+IV+PIY
Sbjct: 193 VSCAKGLGIAIKELFAGKPVLQHPLTWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIY 252
Query: 972 YVMFTSLTILASVIMFKDWDRQNGTQIVTEMCGFVYILSGTFLLHRTKDMVEGSPVILPV 1151
YV FT+ I S I+FK+W ++ + GF I+ G FLLH KD V S LPV
Sbjct: 253 YVFFTTSVITCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKD-VSFSLSSLPV 311
Query: 1152 RISK 1163
K
Sbjct: 312 SFRK 315
>sp|Q8N8Q9|NIPA2_HUMAN Magnesium transporter NIPA2 OS=Homo sapiens GN=NIPA2 PE=2
SV=1
Length = 360
Score = 302 bits (771), Expect = 6e-081
Identities = 153/304 (50%), Positives = 214/304 (70%), Gaps = 2/304 (0%)
Frame = +3
Query: 255 GLVLAISSSLFIGASFIVKKKGLKKAGATGT-RAGVGGYSYLYEPLWWIGVTTMLLGEIA 431
GL LA+SSS+FIG SFI+KKKGL + G+ RAG GG++YL E LWW G+ +M GE+A
Sbjct: 13 GLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVA 72
Query: 432 NFAAYAFAPAILVTPLGALSIIISAVLAHIILLEKLHIFGVLGCALCVVGSTTIVLHAPQ 611
NFAAYAFAPA LVTPLGALS+++SA+L+ L E+L++ G +GC L ++GST +V+HAP+
Sbjct: 73 NFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPK 132
Query: 612 EQEIGSVLEVWNLATEPAFMFYASLIIGAAVFLIIRYVPQYGQTNVMVYIGICSLVGSLS 791
E+EI ++ E+ + +P F+ +A+L++ A+ LI P++GQTN++VYI ICS++G+ S
Sbjct: 133 EEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFS 192
Query: 792 VMSVKALGIALKLTFSGTNQLFYPQTWVFTLVVLTCVITQLNYLNKALDTFNTAIVSPIY 971
V VK LGIA+K F+G L +P W+ L ++ CV TQ+NYLN+ALD FNT+IV+PIY
Sbjct: 193 VSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIY 252
Query: 972 YVMFTSLTILASVIMFKDWDRQNGTQIVTEMCGFVYILSGTFLLHRTKDMVEGSPVILPV 1151
YV FT+ + S I+FK+W ++ + GF I+ G FLLH KD V S LPV
Sbjct: 253 YVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKD-VSFSLASLPV 311
Query: 1152 RISK 1163
K
Sbjct: 312 SFRK 315
>sp|Q5R7Q3|NIPA2_PONAB Magnesium transporter NIPA2 OS=Pongo abelii GN=NIPA2 PE=2
SV=1
Length = 360
Score = 302 bits (771), Expect = 6e-081
Identities = 153/304 (50%), Positives = 214/304 (70%), Gaps = 2/304 (0%)
Frame = +3
Query: 255 GLVLAISSSLFIGASFIVKKKGLKKAGATGT-RAGVGGYSYLYEPLWWIGVTTMLLGEIA 431
GL LA+SSS+FIG SFI+KKKGL + G+ RAG GG++YL E LWW G+ +M GE+A
Sbjct: 13 GLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVA 72
Query: 432 NFAAYAFAPAILVTPLGALSIIISAVLAHIILLEKLHIFGVLGCALCVVGSTTIVLHAPQ 611
NFAAYAFAPA LVTPLGALS+++SA+L+ L E+L++ G +GC L ++GST +V+HAP+
Sbjct: 73 NFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPK 132
Query: 612 EQEIGSVLEVWNLATEPAFMFYASLIIGAAVFLIIRYVPQYGQTNVMVYIGICSLVGSLS 791
E+EI ++ E+ + +P F+ +A+L++ A+ LI P++GQTN++VYI ICS++G+ S
Sbjct: 133 EEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFS 192
Query: 792 VMSVKALGIALKLTFSGTNQLFYPQTWVFTLVVLTCVITQLNYLNKALDTFNTAIVSPIY 971
V VK LGIA+K F+G L +P W+ L ++ CV TQ+NYLN+ALD FNT+IV+PIY
Sbjct: 193 VSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIY 252
Query: 972 YVMFTSLTILASVIMFKDWDRQNGTQIVTEMCGFVYILSGTFLLHRTKDMVEGSPVILPV 1151
YV FT+ + S I+FK+W ++ + GF I+ G FLLH KD V S LPV
Sbjct: 253 YVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKD-VSFSLASLPV 311
Query: 1152 RISK 1163
K
Sbjct: 312 SFRK 315
>sp|Q5RDB8|NIPA3_PONAB Magnesium transporter NIPA3 OS=Pongo abelii GN=NIPAL1
PE=2 SV=1
Length = 410
Score = 296 bits (757), Expect = 3e-079
Identities = 151/289 (52%), Positives = 206/289 (71%), Gaps = 1/289 (0%)
Frame = +3
Query: 255 GLVLAISSSLFIGASFIVKKKGLKKAGATG-TRAGVGGYSYLYEPLWWIGVTTMLLGEIA 431
GLVLA+SSS+FIG+SFI+KKKGL + + G TRAG GG+SYL E LWW+G+ +M +GE A
Sbjct: 71 GLVLAVSSSIFIGSSFILKKKGLLQLASKGITRAGQGGHSYLKEWLWWVGLLSMGVGEAA 130
Query: 432 NFAAYAFAPAILVTPLGALSIIISAVLAHIILLEKLHIFGVLGCALCVVGSTTIVLHAPQ 611
NFAAYAFAPA LVTPLGALS++ISA+L+ L E L+I G +GC L ++GST +V+HAPQ
Sbjct: 131 NFAAYAFAPATLVTPLGALSVLISAILSSYFLNEHLNIHGKIGCILSILGSTVMVIHAPQ 190
Query: 612 EQEIGSVLEVWNLATEPAFMFYASLIIGAAVFLIIRYVPQYGQTNVMVYIGICSLVGSLS 791
E+E+ S+ E+ +P F+ +A ++ ++ LI+ P+ GQTN++VYI ICSL+G+ S
Sbjct: 191 EEEVTSLHEMEMKLRDPGFISFAVIVTVISLVLILIVAPKKGQTNILVYISICSLIGAFS 250
Query: 792 VMSVKALGIALKLTFSGTNQLFYPQTWVFTLVVLTCVITQLNYLNKALDTFNTAIVSPIY 971
V SVK LGIA+K +P +V V++ V TQ+NYLNKALDTFNT+IV+PIY
Sbjct: 251 VSSVKGLGIAIKELIEWKPVYKHPLVFVLLAVLVLSVTTQINYLNKALDTFNTSIVTPIY 310
Query: 972 YVMFTSLTILASVIMFKDWDRQNGTQIVTEMCGFVYILSGTFLLHRTKD 1118
YV FTS+ + S I+F++W I+ + GF I+ G FLLH K+
Sbjct: 311 YVFFTSMVVTCSAILFQEWYGMTAGDIIGTLSGFFTIIIGIFLLHAFKN 359
>sp|Q6NVV3|NIPA3_HUMAN Magnesium transporter NIPA3 OS=Homo sapiens GN=NIPAL1
PE=2 SV=1
Length = 410
Score = 295 bits (754), Expect = 6e-079
Identities = 151/289 (52%), Positives = 205/289 (70%), Gaps = 1/289 (0%)
Frame = +3
Query: 255 GLVLAISSSLFIGASFIVKKKGLKKAGATG-TRAGVGGYSYLYEPLWWIGVTTMLLGEIA 431
GLVLA+SSS+FIG+SFI+KKKGL + + G TRAG GG+SYL E LWW+G+ +M GE A
Sbjct: 71 GLVLAVSSSIFIGSSFILKKKGLLQLASKGFTRAGQGGHSYLKEWLWWVGLLSMGAGEAA 130
Query: 432 NFAAYAFAPAILVTPLGALSIIISAVLAHIILLEKLHIFGVLGCALCVVGSTTIVLHAPQ 611
NFAAYAFAPA LVTPLGALS++ISA+L+ L E L+I G +GC L ++GST +V+HAPQ
Sbjct: 131 NFAAYAFAPATLVTPLGALSVLISAILSSYFLNEHLNIHGKIGCILSILGSTVMVIHAPQ 190
Query: 612 EQEIGSVLEVWNLATEPAFMFYASLIIGAAVFLIIRYVPQYGQTNVMVYIGICSLVGSLS 791
E+E+ S+ E+ +P F+ +A +I ++ LI+ P+ GQTN++VYI ICSL+G+ S
Sbjct: 191 EEEVTSLHEMEMKLRDPGFISFAVIITVISLVLILIVAPKKGQTNILVYISICSLIGAFS 250
Query: 792 VMSVKALGIALKLTFSGTNQLFYPQTWVFTLVVLTCVITQLNYLNKALDTFNTAIVSPIY 971
V SVK LGIA+K +P +V V++ V TQ+NYLNKALDTFNT++V+PIY
Sbjct: 251 VSSVKGLGIAIKELIEWKPVYKHPLVFVLLAVLVLSVTTQINYLNKALDTFNTSLVTPIY 310
Query: 972 YVMFTSLTILASVIMFKDWDRQNGTQIVTEMCGFVYILSGTFLLHRTKD 1118
YV FTS+ + S I+F++W I+ + GF I+ G FLLH K+
Sbjct: 311 YVFFTSMVVTCSAILFQEWYGMTAGDIIGTLSGFFTIIIGIFLLHAFKN 359
>sp|Q9JJC8|NIPA2_MOUSE Magnesium transporter NIPA2 OS=Mus musculus GN=Nipa2 PE=1
SV=1
Length = 359
Score = 293 bits (749), Expect = 2e-078
Identities = 148/304 (48%), Positives = 210/304 (69%), Gaps = 2/304 (0%)
Frame = +3
Query: 255 GLVLAISSSLFIGASFIVKKKGLKKAGATGT-RAGVGGYSYLYEPLWWIGVTTMLLGEIA 431
GL LA++SS+FIG SFI+KKKGL + G+ RAG GG++YL E LWW G+ +M GE+A
Sbjct: 13 GLGLAMTSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVA 72
Query: 432 NFAAYAFAPAILVTPLGALSIIISAVLAHIILLEKLHIFGVLGCALCVVGSTTIVLHAPQ 611
NFAAYAFAPA LVTPLGALS+++SA+L+ L E+L++ G +GC L ++GST +V+HAP+
Sbjct: 73 NFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPK 132
Query: 612 EQEIGSVLEVWNLATEPAFMFYASLIIGAAVFLIIRYVPQYGQTNVMVYIGICSLVGSLS 791
E+EI ++ E+ + +P F+ +A+ ++ A+ I P++GQTN++VYI ICS++G+ S
Sbjct: 133 EEEIETLNEMSHKLGDPGFVVFATFVVIVALIFIFVVGPRHGQTNILVYITICSVIGAFS 192
Query: 792 VMSVKALGIALKLTFSGTNQLFYPQTWVFTLVVLTCVITQLNYLNKALDTFNTAIVSPIY 971
V VK LGIA+K +G L +P W+ ++ CV TQ+NYLN+ALD FNT+IV+PIY
Sbjct: 193 VSCVKGLGIAIKELLAGKPVLQHPLAWILLFSLVVCVSTQINYLNRALDIFNTSIVTPIY 252
Query: 972 YVMFTSLTILASVIMFKDWDRQNGTQIVTEMCGFVYILSGTFLLHRTKDMVEGSPVILPV 1151
YV FT+ + S I+FK+W ++ + GF I+ G FLLH KD V S LPV
Sbjct: 253 YVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKD-VSFSLASLPV 311
Query: 1152 RISK 1163
K
Sbjct: 312 SFRK 315
>sp|Q8BMW7|NIPA3_MOUSE Magnesium transporter NIPA3 OS=Mus musculus GN=Nipal1
PE=1 SV=2
Length = 416
Score = 288 bits (736), Expect = 7e-077
Identities = 151/289 (52%), Positives = 202/289 (69%), Gaps = 1/289 (0%)
Frame = +3
Query: 255 GLVLAISSSLFIGASFIVKKKGLKKAGATG-TRAGVGGYSYLYEPLWWIGVTTMLLGEIA 431
GLVLAISSS+FIG+SFI+KKKGL + G TRAG GG+SYL E LWW G+ +M GE A
Sbjct: 71 GLVLAISSSVFIGSSFILKKKGLLQLADKGITRAGQGGHSYLKEWLWWAGLLSMGAGEAA 130
Query: 432 NFAAYAFAPAILVTPLGALSIIISAVLAHIILLEKLHIFGVLGCALCVVGSTTIVLHAPQ 611
NFAAYAFAPA LVTPLGALS++ISA+L+ L E+L+I G +GC L V+GST +V+HAPQ
Sbjct: 131 NFAAYAFAPATLVTPLGALSVLISAILSSYFLNERLNIHGKIGCILSVLGSTVMVIHAPQ 190
Query: 612 EQEIGSVLEVWNLATEPAFMFYASLIIGAAVFLIIRYVPQYGQTNVMVYIGICSLVGSLS 791
E E+ S+ E+ +P F+ +A +I ++ LI+ P+ GQTN++VYI ICSL+G+ S
Sbjct: 191 EGEVTSLHEMEMKLRDPGFVSFAVIISVISLVLILIVAPKKGQTNILVYIAICSLIGAFS 250
Query: 792 VMSVKALGIALKLTFSGTNQLFYPQTWVFTLVVLTCVITQLNYLNKALDTFNTAIVSPIY 971
V SVK LGIA+K P ++ ++ V TQ+NYLNKALDTFNT++V+PIY
Sbjct: 251 VSSVKGLGIAIKELLERKPVYKDPLFFILLTMLALSVTTQINYLNKALDTFNTSLVTPIY 310
Query: 972 YVMFTSLTILASVIMFKDWDRQNGTQIVTEMCGFVYILSGTFLLHRTKD 1118
YV FTS+ + S I+F++W I+ + GF I++G FLLH K+
Sbjct: 311 YVFFTSMVVTCSAILFQEWYGMKAGDIIGTLSGFFTIINGIFLLHAFKN 359
>sp|Q0D2K0|NIPA4_HUMAN Magnesium transporter NIPA4 OS=Homo sapiens GN=NIPAL4
PE=1 SV=3
Length = 466
Score = 283 bits (722), Expect = 3e-075
Identities = 135/290 (46%), Positives = 202/290 (69%), Gaps = 1/290 (0%)
Frame = +3
Query: 255 GLVLAISSSLFIGASFIVKKKGLKKAGATG-TRAGVGGYSYLYEPLWWIGVTTMLLGEIA 431
GL LA SS IG+S I+KKKGL + ATG TRA GG+ YL + +WW G TM GE+A
Sbjct: 121 GLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDAMWWAGFLTMAAGEVA 180
Query: 432 NFAAYAFAPAILVTPLGALSIIISAVLAHIILLEKLHIFGVLGCALCVVGSTTIVLHAPQ 611
NF AYAFAPA +VTPLGALS++ISA+L+ L E L++ G LGC +CV GST +V+HAP+
Sbjct: 181 NFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGSTVMVIHAPE 240
Query: 612 EQEIGSVLEVWNLATEPAFMFYASLIIGAAVFLIIRYVPQYGQTNVMVYIGICSLVGSLS 791
E+++ +++E+ + + F+ +A L++ + + LI P+YGQ N+++YI ICS++G+ S
Sbjct: 241 EEKVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIIICSVIGAFS 300
Query: 792 VMSVKALGIALKLTFSGTNQLFYPQTWVFTLVVLTCVITQLNYLNKALDTFNTAIVSPIY 971
V +VK LGI +K F G + +P ++ +L++ + TQ+N+LN+ALD FNT++V PIY
Sbjct: 301 VAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLNRALDIFNTSLVFPIY 360
Query: 972 YVMFTSLTILASVIMFKDWDRQNGTQIVTEMCGFVYILSGTFLLHRTKDM 1121
YV FT++ + +S+I+FK+W + I + GFV I+ G F+LH KD+
Sbjct: 361 YVFFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVFMLHAFKDL 410
>sp|Q8BZF2|NIPA4_MOUSE Magnesium transporter NIPA4 OS=Mus musculus GN=Nipal4
PE=1 SV=1
Length = 406
Score = 280 bits (715), Expect = 2e-074
Identities = 133/290 (45%), Positives = 201/290 (69%), Gaps = 1/290 (0%)
Frame = +3
Query: 255 GLVLAISSSLFIGASFIVKKKGLKKAGATG-TRAGVGGYSYLYEPLWWIGVTTMLLGEIA 431
G+ LA S IG S I+KKKGL + ATG TRA GGY YL +P+WW G+ TM GE+A
Sbjct: 61 GVGLAFLSCFLIGTSVILKKKGLIRLVATGATRAVNGGYGYLKDPMWWAGMATMSAGEVA 120
Query: 432 NFAAYAFAPAILVTPLGALSIIISAVLAHIILLEKLHIFGVLGCALCVVGSTTIVLHAPQ 611
NF AYAFAPA +VTPLGALS++ISA+ + L E L++ G LGC +C+ GST +V+HAP+
Sbjct: 121 NFGAYAFAPATVVTPLGALSVLISAIFSSYCLGESLNLLGKLGCVICMAGSTVMVIHAPK 180
Query: 612 EQEIGSVLEVWNLATEPAFMFYASLIIGAAVFLIIRYVPQYGQTNVMVYIGICSLVGSLS 791
E+++ +V E+ + + F+ +A L++ + + LI P+YGQ N+++YI ICS++GS S
Sbjct: 181 EEKVTTVAEMASKMKDTGFIVFAVLLVVSCLILIFIVAPRYGQRNILIYIIICSVIGSFS 240
Query: 792 VMSVKALGIALKLTFSGTNQLFYPQTWVFTLVVLTCVITQLNYLNKALDTFNTAIVSPIY 971
V +VK LG+ ++ F G + +P ++ +L++ +I Q+N+LN+ALD FNT++V PIY
Sbjct: 241 VTAVKGLGVTIRNFFQGLPVVRHPLPYILSLILGLSIIIQVNFLNRALDIFNTSLVFPIY 300
Query: 972 YVMFTSLTILASVIMFKDWDRQNGTQIVTEMCGFVYILSGTFLLHRTKDM 1121
YV FT++ + +S+++FK+W + IV + GFV I+ G F+LH KD+
Sbjct: 301 YVFFTTVVVASSIVLFKEWYTMSAVDIVGTLSGFVTIILGVFMLHAFKDL 350
>sp|Q7RTP0|NIPA1_HUMAN Magnesium transporter NIPA1 OS=Homo sapiens GN=NIPA1 PE=1
SV=1
Length = 329
Score = 209 bits (530), Expect = 6e-053
Identities = 109/290 (37%), Positives = 170/290 (58%), Gaps = 9/290 (3%)
Frame = +3
Query: 255 GLVLAISSSLFIGASFIVKKKGLKKAGATGTRAGVGGYSYLYEPLWWIGVTTMLLGEIAN 434
GL +A+ SSL G++F+++KKG+ +A GT SYL + +WW G M +G+I N
Sbjct: 31 GLGVAVVSSLVNGSTFVLQKKGIVRAKRRGT-------SYLTDIVWWAGTIAMAVGQIGN 83
Query: 435 FAAYAFAPAILVTPLGALSIIISAVLAHIILLEKLHIFGVLGCALCVVGSTTIVLHAPQE 614
F AY P +LVTPLGAL + ++LA +L EKL+I G LGC L GS +++H+P+
Sbjct: 84 FLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVVLIIHSPKS 143
Query: 615 QEIGSVLEVWNLATEPAFMFYASLIIGAAVFLIIRYVPQYGQTNVMVYIGICSLVGSLSV 794
+ + + E+ T P F+ Y +++ + LI P +G TN+MVYI ICSL+GS +V
Sbjct: 144 ESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISICSLLGSFTV 203
Query: 795 MSVKALGIALK--LTFSGTNQLFYPQTWVFTLVVLTCVITQLNYLNKALDTFNTAIVSPI 968
S K +G+A + L + ++Q V V+ +I Q Y+NKAL+ F++++ I
Sbjct: 204 PSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECFDSSVFGAI 263
Query: 969 YYVMFTSLTILASVIMFKDWDRQNGTQIVTEMCGFVYILSGTFLLHRTKD 1118
YYV+FT+L +LAS I+F++W + CGF + G L+ K+
Sbjct: 264 YYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKE 313
>sp|Q8BHK1|NIPA1_MOUSE Magnesium transporter NIPA1 OS=Mus musculus GN=Nipa1 PE=1
SV=1
Length = 323
Score = 209 bits (530), Expect = 6e-053
Identities = 109/290 (37%), Positives = 170/290 (58%), Gaps = 9/290 (3%)
Frame = +3
Query: 255 GLVLAISSSLFIGASFIVKKKGLKKAGATGTRAGVGGYSYLYEPLWWIGVTTMLLGEIAN 434
GL +A+ SSL G++F+++KKG+ +A GT SYL + +WW G M +G+I N
Sbjct: 25 GLGVAVVSSLVNGSTFVLQKKGIVRAKRRGT-------SYLTDIVWWAGTIAMAVGQIGN 77
Query: 435 FAAYAFAPAILVTPLGALSIIISAVLAHIILLEKLHIFGVLGCALCVVGSTTIVLHAPQE 614
F AY P +LVTPLGAL + ++LA +L EKL+I G LGC L GS +++H+P+
Sbjct: 78 FLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVVLIIHSPKS 137
Query: 615 QEIGSVLEVWNLATEPAFMFYASLIIGAAVFLIIRYVPQYGQTNVMVYIGICSLVGSLSV 794
+ + + E+ T P F+ Y +++ + LI P +G TN+MVYI ICSL+GS +V
Sbjct: 138 ESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISICSLLGSFTV 197
Query: 795 MSVKALGIALK--LTFSGTNQLFYPQTWVFTLVVLTCVITQLNYLNKALDTFNTAIVSPI 968
S K +G+A + L + ++Q V V+ +I Q Y+NKAL+ F++++ I
Sbjct: 198 PSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECFDSSVFGAI 257
Query: 969 YYVMFTSLTILASVIMFKDWDRQNGTQIVTEMCGFVYILSGTFLLHRTKD 1118
YYV+FT+L +LAS I+F++W + CGF + G L+ K+
Sbjct: 258 YYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKE 307
>sp|Q5RD30|NPAL3_PONAB NIPA-like protein 3 OS=Pongo abelii GN=NIPAL3 PE=2 SV=1
Length = 406
Score = 136 bits (342), Expect = 4e-031
Identities = 89/308 (28%), Positives = 163/308 (52%), Gaps = 22/308 (7%)
Frame = +3
Query: 222 SYKGMSSDNIKGLVLAISSSLFIGASFIVKKK-GLKKAGATGTRAGVGGYSYLYEPLWWI 398
SYK +N+ G +LAI L + + ++K ++ AG+ RA Y WW+
Sbjct: 29 SYK----ENLIGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRA------YFKTKTWWL 78
Query: 399 GVTTMLLGEIANFAAYAFAPAILVTPLGALSIIISAVLAHIILLEK--------LHIFGV 554
G+ MLLGE+ FA+YAFAP L+ PL A+S+I SA++ I + EK +I
Sbjct: 79 GLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYILSF 138
Query: 555 LGCALCVVGSTTIVLHAPQEQEIGSVLEVWNLATEPAFMFYASLIIGAAVF-LIIRYVPQ 731
+GC L VVG+ +V AP +E + V F+ Y +++ +F L++ + +
Sbjct: 139 VGCGLAVVGTYLLVTFAPNSREKMTGENVTRHLVSWPFLLY--MLVEIILFCLLLYFYKE 196
Query: 732 YGQTNVMVYIGICSLVGSLSVMSVKALGIALKLTFSGTNQLFYPQTWVFTLVVLTCVITQ 911
N++V + + +L+GS++V++VKA+ L L+ G QL YP +V + ++ + Q
Sbjct: 197 KNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQ 256
Query: 912 LNYLNKALDTFNTAIVSPIYYVMFTSLTILASVIMFKDWDRQNGTQIVTEMCGFVYILSG 1091
+L++A +++++++ + Y++ T++ I A I + D+ ++ I G + G
Sbjct: 257 AAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLG 316
Query: 1092 TFLLHRTK 1115
FL+ R +
Sbjct: 317 VFLITRNR 324
>sp|Q6P499|NPAL3_HUMAN NIPA-like protein 3 OS=Homo sapiens GN=NIPAL3 PE=1 SV=1
Length = 406
Score = 136 bits (340), Expect = 6e-031
Identities = 88/308 (28%), Positives = 162/308 (52%), Gaps = 22/308 (7%)
Frame = +3
Query: 222 SYKGMSSDNIKGLVLAISSSLFIGASFIVKKK-GLKKAGATGTRAGVGGYSYLYEPLWWI 398
SYK +N+ G +LAI L + + ++K ++ AG+ RA Y WW+
Sbjct: 29 SYK----ENLIGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRA------YFKTKTWWL 78
Query: 399 GVTTMLLGEIANFAAYAFAPAILVTPLGALSIIISAVLAHIILLEK--------LHIFGV 554
G+ MLLGE+ FA+YAFAP L+ PL A+S+I SA++ I + EK ++
Sbjct: 79 GLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSF 138
Query: 555 LGCALCVVGSTTIVLHAPQEQEIGSVLEVWNLATEPAFMFYASLIIGAAVF-LIIRYVPQ 731
+GC L VVG+ +V AP E + V F+ Y +++ +F L++ + +
Sbjct: 139 VGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLY--MLVEIILFCLLLYFYKE 196
Query: 732 YGQTNVMVYIGICSLVGSLSVMSVKALGIALKLTFSGTNQLFYPQTWVFTLVVLTCVITQ 911
N++V + + +L+GS++V++VKA+ L L+ G QL YP +V + ++ + Q
Sbjct: 197 KNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQ 256
Query: 912 LNYLNKALDTFNTAIVSPIYYVMFTSLTILASVIMFKDWDRQNGTQIVTEMCGFVYILSG 1091
+L++A +++++++ + Y++ T++ I A I + D+ ++ I G + G
Sbjct: 257 AAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLG 316
Query: 1092 TFLLHRTK 1115
FL+ R +
Sbjct: 317 VFLITRNR 324
>sp|Q9H841|NPAL2_HUMAN NIPA-like protein 2 OS=Homo sapiens GN=NIPAL2 PE=2 SV=1
Length = 368
Score = 131 bits (327), Expect = 2e-029
Identities = 86/313 (27%), Positives = 153/313 (48%), Gaps = 10/313 (3%)
Frame = +3
Query: 186 GGGGGGGGGWRDSYKGMSSDNIKGLVLAISSSLFIGASFIVKK-KGLKKAGATGTRAGVG 362
G G G G + + ++ G++LAI +L I S ++K L+ A R
Sbjct: 27 GAPGAGNGSLSGDWYRRNQIHLFGVLLAILGNLVISISLNIQKYSHLQLAQQEHPR---- 82
Query: 363 GYSYLYEPLWWIGVTTMLLGEIANFAAYAFAPAILVTPLGALSIIISAVLAHIILLEKLH 542
Y LWW GV M +GE NFAAY FAP L+ PLG +S+ SA+++ L + L
Sbjct: 83 --PYFKSVLWWGGVLLMAVGETGNFAAYGFAPITLIAPLGCVSVTGSAIISVTFLKDNLR 140
Query: 543 IFGVLGCALCVVGSTTIVLHAPQEQEIGSVLEVWNLATEPAFMFYASLIIGAAVFLIIRY 722
+LG L G+ +V AP + S V F+ Y +I+ +F I+ Y
Sbjct: 141 ASDLLGTTLAFAGTYLLVNFAPNITQAISARTVQYYLVGWQFLIY--VILEILIFCILLY 198
Query: 723 -VPQYGQTNVMVYIGICSLVGSLSVMSVKALGIALKLTFSGTNQLFYPQTWVFTLVVLTC 899
+ G ++++ + + +++ SL+V+SVKA+ + + QL YP ++ ++++
Sbjct: 199 FYKRKGMKHMVILLTLVAILASLTVISVKAVSGMITFSVMDKMQLTYPIFYIMFIIMIAS 258
Query: 900 VITQLNYLNKALDTFNTAIVSPIYYVMFTSLTILASVIMFKDWDRQNGTQIVTEMCGFVY 1079
+ Q+ +LN+A +NT V P+ ++ FT I+A +I ++++ + + G
Sbjct: 259 CVFQVKFLNQATKLYNTTTVVPVNHIFFTISAIIAGIIFYQEFLGAPFLTVFIYLFGCFL 318
Query: 1080 ILSGTFLLHRTKD 1118
G FL+ R ++
Sbjct: 319 SFLGVFLVTRNRE 331
>sp|Q8BGN5|NPAL3_MOUSE NIPA-like protein 3 OS=Mus musculus GN=Nipal3 PE=2 SV=1
Length = 410
Score = 127 bits (318), Expect = 2e-028
Identities = 79/279 (28%), Positives = 150/279 (53%), Gaps = 22/279 (7%)
Frame = +3
Query: 222 SYKGMSSDNIKGLVLAISSSLFIGASFIVKKK-GLKKAGATGTRAGVGGYSYLYEPLWWI 398
SYK +N+ G +LAI L + + ++K ++ AG+ RA Y WW+
Sbjct: 33 SYK----ENLIGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRA------YFKTKTWWL 82
Query: 399 GVTTMLLGEIANFAAYAFAPAILVTPLGALSIIISAVLAHIILLEK--------LHIFGV 554
G+ +LLGE+ FA+YAFAP L+ PL A+S+I SA++ I + EK ++
Sbjct: 83 GLLLLLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFVRRYVLSF 142
Query: 555 LGCALCVVGSTTIVLHAPQEQEIGSVLEVWNLATEPAFMFYASLIIGAAVF-LIIRYVPQ 731
+GC L +VG+ +V AP E + + F+ Y +++ +F L++ + +
Sbjct: 143 VGCGLAIVGTYLLVTFAPNSHEKMTGENIARHLVSWPFLLY--MLVAIVLFCLLLYFYKE 200
Query: 732 YGQTNVMVYIGICSLVGSLSVMSVKALGIALKLTFSGTNQLFYPQTWVFTLVVLTCVITQ 911
+++V + + +L+GS++V++VKA+ L L+ G QL YP +V + ++ I Q
Sbjct: 201 RNANSIVVILLLVALLGSMTVVTVKAVSGMLVLSIQGNLQLDYPIFYVMFVCMVATAIYQ 260
Query: 912 LNYLNKALDTFNTAIVSPIYYVMFTSLTILASVIMFKDW 1028
+L++A +++++++ + Y++ T+ I A I + D+
Sbjct: 261 ATFLSEASQIYDSSLIASVGYILSTTAAITAGAIFYLDF 299
>sp|Q91WC7|NPAL2_MOUSE NIPA-like protein 2 OS=Mus musculus GN=Nipal2 PE=2 SV=1
Length = 383
Score = 123 bits (308), Expect = 3e-027
Identities = 86/310 (27%), Positives = 152/310 (49%), Gaps = 10/310 (3%)
Frame = +3
Query: 195 GGGGGGWRDSYKGMSSDNIKGLVLAISSSLFIGASFIVKK-KGLKKAGATGTRAGVGGYS 371
G G G ++ + ++ G++LAI +L I S ++K L A +
Sbjct: 30 GPGNGSLSSAWYRRNQIHLFGVLLAILGNLVISISLNIQKYSHLHLAQKEHPK------P 83
Query: 372 YLYEPLWWIGVTTMLLGEIANFAAYAFAPAILVTPLGALSIIISAVLAHIILLEKLHIFG 551
Y LW GV LGE NFAAY AP L+ PLG +S+ SA+++ + L E L
Sbjct: 84 YFKSVLWLSGVLLTALGETGNFAAYGVAPITLIAPLGCMSVTGSAIISVLFLKENLRASD 143
Query: 552 VLGCALCVVGSTTIVLHAPQEQEIGSVLEVWNLATEPAFMFYASLIIGAAVFLIIRYV-P 728
+LG L G+ +V AP + S V F+ Y +I+ VF I+ Y
Sbjct: 144 LLGMTLAFAGTYLLVNFAPNITQAISARTVQYYFVGWQFLVY--VILEILVFCILLYFHK 201
Query: 729 QYGQTNVMVYIGICSLVGSLSVMSVKALGIALKLTFSGTNQLFYPQTWVFTLVVLTCVIT 908
+ G +++V + + +L+ SL+V+SVKA+ + L+ +G QL Y ++ ++++ +
Sbjct: 202 RKGMKHIVVLLTLVALLASLTVISVKAVSGMITLSVTGKMQLTYAIFYIMLVIMIASCVF 261
Query: 909 QLNYLNKALDTFNTAIVSPIYYVMFTSLTILASVIMFKDWDRQNGTQIVTEMCGFVYILS 1088
Q+ +LN+A + + V P+ +V FT+ I+A +I ++++ + + G
Sbjct: 262 QVKFLNQATELYTMTTVVPVNHVFFTTSAIIAGIIFYQEFLGAAFLTVFIYLFGCFLSFL 321
Query: 1089 GTFLLHRTKD 1118
G FL+ R ++
Sbjct: 322 GVFLVTRNRE 331
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,590,037,747
Number of Sequences: 518415
Number of Extensions: 9590037747
Number of Successful Extensions: 72030089
Number of sequences better than 0.0: 0
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