BLASTX 7.6.2
Query= UN02545 /QuerySize=1460
(1459 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8QZR1|ATTY_MOUSE Tyrosine aminotransferase OS=Mus musculus G... 266 4e-070
sp|Q58CZ9|ATTY_BOVIN Tyrosine aminotransferase OS=Bos taurus GN=... 265 7e-070
sp|P04694|ATTY_RAT Tyrosine aminotransferase OS=Rattus norvegicu... 262 6e-069
sp|P17735|ATTY_HUMAN Tyrosine aminotransferase OS=Homo sapiens G... 261 1e-068
sp|Q54K95|ATTY_DICDI Tyrosine aminotransferase OS=Dictyostelium ... 242 9e-063
sp|P33447|ATTY_TRYCR Tyrosine aminotransferase OS=Trypanosoma cr... 213 3e-054
sp|O67781|AAT_AQUAE Aspartate aminotransferase OS=Aquifex aeolic... 135 9e-031
sp|P0A960|YFBQ_ECOL6 Uncharacterized aminotransferase yfbQ OS=Es... 130 3e-029
sp|P0A959|YFBQ_ECOLI Uncharacterized aminotransferase yfbQ OS=Es... 130 3e-029
sp|P0A961|YFBQ_SHIFL Uncharacterized aminotransferase yfbQ OS=Sh... 130 3e-029
sp|Q60317|AAT1_METJA Probable aspartate aminotransferase 1 OS=Me... 117 2e-025
sp|Q9V0L2|AAT_PYRAB Aspartate aminotransferase OS=Pyrococcus aby... 107 2e-022
sp|P52892|ALAT_YEAST Probable alanine aminotransferase OS=Saccha... 101 2e-020
sp|P52893|ALAM_YEAST Probable alanine aminotransferase, mitochon... 94 2e-018
sp|Q8GYY0|1A112_ARATH Probable aminotransferase ACS12 OS=Arabido... 88 1e-016
sp|Q7NDX4|DAPAT_GLOVI LL-diaminopimelate aminotransferase OS=Glo... 81 2e-014
sp|Q30ZX9|DAPAT_DESDG LL-diaminopimelate aminotransferase OS=Des... 79 7e-014
sp|B8DJJ6|DAPAT_DESVM LL-diaminopimelate aminotransferase OS=Des... 79 1e-013
sp|P47039|BNA3_YEAST Probable kynurenine--oxoglutarate transamin... 71 2e-011
sp|O14209|YDT4_SCHPO Uncharacterized aminotransferase C6B12.04c ... 70 3e-011
>sp|Q8QZR1|ATTY_MOUSE Tyrosine aminotransferase OS=Mus musculus GN=Tat PE=2
SV=1
Length = 454
Score = 266 bits (678), Expect = 4e-070
Identities = 141/408 (34%), Positives = 230/408 (56%), Gaps = 6/408 (1%)
Frame = -2
Query: 1392 RWNFGANEVVERSSSLSIREYLNTLISNLNKGDTRSVIALGHGDPSPFPRFSTDPSAVKA 1213
RWN +++ ++ + IR ++ + + ++VI+L GDP+ F TDP +A
Sbjct: 40 RWNVRPSDMSNKTFN-PIRAIVDNM--KVKPNPNKTVISLSIGDPTVFGNLPTDPEVTQA 96
Query: 1212 ICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLSYQISPNDVHITCGCLQAIEILLSSL 1033
+ DA+ S K+N YA + G +R+ VA Y + DV +T GC QAIE+ L+ L
Sbjct: 97 MKDALDSGKYNGYAPSIGYLSSREEVASYYHCP-EAPLEAKDVILTSGCSQAIELCLAVL 155
Query: 1032 AKPGANILLPRPTYPMYDSRASFSQLEIRYFDLLPENGWDVDLDAVEALADDKTIAIVVV 853
A PG NIL+PRP + +Y + A +E++ ++LLPE W++DL +E+L D+KT +VV
Sbjct: 156 ANPGQNILIPRPGFSLYRTLAESMGIEVKLYNLLPEKSWEIDLKQLESLIDEKTACLVVN 215
Query: 852 NPCNPCGNVFSRQHLQKIAETACKLGILLIADEVYDHYAFGDKPFVSMAEFAEIVPVVLL 673
NP NPCG+VFS++HLQKI A + + ++ADE+Y F D + MA + VP++
Sbjct: 216 NPSNPCGSVFSKRHLQKILAVAERQCVPILADEIYGDMVFSDCKYEPMATLSTNVPILSC 275
Query: 672 GAISKRWFVPGWRLGWMVTLDPHSIMKDSGFLQSLTNVINISTDAATFVQGAIPDILGNT 493
G ++KRW VPGWRLGW++ D I + L + T VQGA+ IL T
Sbjct: 276 GGLAKRWLVPGWRLGWILIHDRRDIFGNE-IRDGLVKLSQRILGPCTIVQGALKSILQRT 334
Query: 492 KEEFFSLKLETVRECAEICYEEIMKIPCITCPSKPEGSMFTMVKLNLSLLGDISDDLDFC 313
+EF+ L ++ A++CY + IP + P +P G+M+ MV + + + +D++F
Sbjct: 335 PQEFYQDTLSFLKSNADLCYGALSAIPGLQ-PVRPSGAMYLMVGIEMEHFPEFENDVEFT 393
Query: 312 CKLAKEESLIILPGRAVGLENWLRITFAVELDLLIDGFSRLKNFAQRH 169
+L E+S+ LP N+ R+ V ++++ SR++ F ++H
Sbjct: 394 ERLIAEQSVHCLPATCFEYPNFFRVVITVPEVMMLEACSRIQEFCEQH 441
>sp|Q58CZ9|ATTY_BOVIN Tyrosine aminotransferase OS=Bos taurus GN=TAT PE=2 SV=1
Length = 447
Score = 265 bits (676), Expect = 7e-070
Identities = 141/426 (33%), Positives = 237/426 (55%), Gaps = 8/426 (1%)
Frame = -2
Query: 1440 VTVSDQKKKMSEIGAK--RWNFGANEVVERSSSLSIREYLNTLISNLNKGDTRSVIALGH 1267
V V+ + + ++ ++ RW+ +++ ++ + IR ++ + + +++IAL
Sbjct: 15 VNVAGRSSVLGKVKSRKARWSVRPSDMSNKTFN-PIRAIVDNM--KVKPNPNKTMIALSI 71
Query: 1266 GDPSPFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLSYQISPND 1087
GDP+ F TDP +A+ DA+ S KFN Y + G +R+ VA Y + D
Sbjct: 72 GDPTVFGNLPTDPEVTQAMKDALDSGKFNGYVPSIGYLSSREEVASYYHCP-EAPLEAKD 130
Query: 1086 VHITCGCLQAIEILLSSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLLPENGWDVD 907
V +T GC QAIE+ L+ LA PG NIL+PRP + +Y + A +E++ ++LLPE W++D
Sbjct: 131 VILTSGCSQAIELCLAVLANPGQNILVPRPGFSLYRTLAESMGIEVKLYNLLPEKNWEID 190
Query: 906 LDAVEALADDKTIAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEVYDHYAFGD 727
L +E+L D+KT+ ++V NP NPCG+VFSR+HLQKI A + + ++ADE+Y F D
Sbjct: 191 LKQLESLIDEKTVCLIVNNPSNPCGSVFSRRHLQKILAVAARQCVPILADEIYGDMVFSD 250
Query: 726 KPFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMVTLDPHSIMKDSGFLQSLTNVINIS 547
F +A + VP++ G ++KRW VPGWR+GW++ D I + LT +
Sbjct: 251 SKFEPLATLSSKVPILSCGGLAKRWLVPGWRMGWILIHDRRDIFGNE-IRDGLTKLSQRI 309
Query: 546 TDAATFVQGAIPDILGNTKEEFFSLKLETVRECAEICYEEIMKIPCITCPSKPEGSMFTM 367
T VQGA+ IL T F+ L ++ A++CY + IP + P P G+M+ M
Sbjct: 310 LGPCTLVQGALKSILCRTPRVFYHNTLSFLKSNADLCYGALAAIPGLR-PIHPSGAMYLM 368
Query: 366 VKLNLSLLGDISDDLDFCCKLAKEESLIILPGRAVGLENWLRITFAVELDLLIDGFSRLK 187
V + + + +D++F +L E+S+ LP N+ R+ V ++++ SR++
Sbjct: 369 VGIEMEHFPEFENDVEFTEQLVAEQSVHCLPATCFEYPNFFRVVITVPEVMMLEACSRIQ 428
Query: 186 NFAQRH 169
F ++H
Sbjct: 429 EFCEQH 434
>sp|P04694|ATTY_RAT Tyrosine aminotransferase OS=Rattus norvegicus GN=Tat PE=1
SV=1
Length = 454
Score = 262 bits (668), Expect = 6e-069
Identities = 138/401 (34%), Positives = 226/401 (56%), Gaps = 7/401 (1%)
Frame = -2
Query: 1359 RSSSLSIREY--LNTLISNL--NKGDTRSVIALGHGDPSPFPRFSTDPSAVKAICDAVSS 1192
R S +S + + + ++ N+ ++VI+L GDP+ F TDP +A+ DA+ S
Sbjct: 44 RPSDMSNKTFNPIRAIVDNMKVQPNPNKTVISLSIGDPTVFGNLPTDPEVTQAMKDALDS 103
Query: 1191 NKFNNYASASGIPVARKAVAEYLSRDLSYQISPNDVHITCGCLQAIEILLSSLAKPGANI 1012
K+N YA + G +R+ VA Y + DV +T GC QAIE+ L+ LA PG NI
Sbjct: 104 GKYNGYAPSIGYLSSREEVASYYHCH-EAPLEAKDVILTSGCSQAIELCLAVLANPGQNI 162
Query: 1011 LLPRPTYPMYDSRASFSQLEIRYFDLLPENGWDVDLDAVEALADDKTIAIVVVNPCNPCG 832
L+PRP + +Y + A +E++ ++LLPE W++DL +E+L D+KT +VV NP NPCG
Sbjct: 163 LIPRPGFSLYRTLAESMGIEVKLYNLLPEKSWEIDLKQLESLIDEKTACLVVNNPSNPCG 222
Query: 831 NVFSRQHLQKIAETACKLGILLIADEVYDHYAFGDKPFVSMAEFAEIVPVVLLGAISKRW 652
+VFS++HLQKI A + + ++ADE+Y F D + +A + VP++ G ++KRW
Sbjct: 223 SVFSKRHLQKILAVAERQCVPILADEIYGDMVFSDCKYEPLANLSTNVPILSCGGLAKRW 282
Query: 651 FVPGWRLGWMVTLDPHSIMKDSGFLQSLTNVINISTDAATFVQGAIPDILGNTKEEFFSL 472
VPGWRLGW++ D I + L + T VQGA+ IL T +EF+
Sbjct: 283 LVPGWRLGWILIHDRRDIFGNE-IRDGLVKLSQRILGPCTIVQGALKSILQRTPQEFYHD 341
Query: 471 KLETVRECAEICYEEIMKIPCITCPSKPEGSMFTMVKLNLSLLGDISDDLDFCCKLAKEE 292
L ++ A++CY + IP + P +P G+M+ MV + + + +D++F +L E+
Sbjct: 342 TLSFLKSNADLCYGALAAIPGLQ-PVRPSGAMYLMVGIEMEHFPEFENDVEFTERLIAEQ 400
Query: 291 SLIILPGRAVGLENWLRITFAVELDLLIDGFSRLKNFAQRH 169
++ LP N+ R+ V ++++ SR++ F ++H
Sbjct: 401 AVHCLPATCFEYPNFFRVVITVPEVMMLEACSRIQEFCEQH 441
>sp|P17735|ATTY_HUMAN Tyrosine aminotransferase OS=Homo sapiens GN=TAT PE=1
SV=1
Length = 454
Score = 261 bits (665), Expect = 1e-068
Identities = 135/408 (33%), Positives = 230/408 (56%), Gaps = 6/408 (1%)
Frame = -2
Query: 1392 RWNFGANEVVERSSSLSIREYLNTLISNLNKGDTRSVIALGHGDPSPFPRFSTDPSAVKA 1213
RW+ +++ +++ + IR ++ + + +++I+L GDP+ F TDP +A
Sbjct: 40 RWSVRPSDMAKKTFN-PIRAIVDNM--KVKPNPNKTMISLSIGDPTVFGNLPTDPEVTQA 96
Query: 1212 ICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLSYQISPNDVHITCGCLQAIEILLSSL 1033
+ DA+ S K+N YA + G +R+ +A Y + DV +T GC QAI++ L+ L
Sbjct: 97 MKDALDSGKYNGYAPSIGFLSSREEIASYYHCP-EAPLEAKDVILTSGCSQAIDLCLAVL 155
Query: 1032 AKPGANILLPRPTYPMYDSRASFSQLEIRYFDLLPENGWDVDLDAVEALADDKTIAIVVV 853
A PG NIL+PRP + +Y + A +E++ ++LLPE W++DL +E L D+KT ++V
Sbjct: 156 ANPGQNILVPRPGFSLYKTLAESMGIEVKLYNLLPEKSWEIDLKQLEYLIDEKTACLIVN 215
Query: 852 NPCNPCGNVFSRQHLQKIAETACKLGILLIADEVYDHYAFGDKPFVSMAEFAEIVPVVLL 673
NP NPCG+VFS++HLQKI A + + ++ADE+Y F D + +A + VP++
Sbjct: 216 NPSNPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVFSDCKYEPLATLSTDVPILSC 275
Query: 672 GAISKRWFVPGWRLGWMVTLDPHSIMKDSGFLQSLTNVINISTDAATFVQGAIPDILGNT 493
G ++KRW VPGWRLGW++ D I + L + T VQGA+ IL T
Sbjct: 276 GGLAKRWLVPGWRLGWILIHDRRDIFGNE-IRDGLVKLSQRILGPCTIVQGALKSILCRT 334
Query: 492 KEEFFSLKLETVRECAEICYEEIMKIPCITCPSKPEGSMFTMVKLNLSLLGDISDDLDFC 313
EF+ L ++ A++CY + IP + P +P G+M+ MV + + + +D++F
Sbjct: 335 PGEFYHNTLSFLKSNADLCYGALAAIPGLR-PVRPSGAMYLMVGIEMEHFPEFENDVEFT 393
Query: 312 CKLAKEESLIILPGRAVGLENWLRITFAVELDLLIDGFSRLKNFAQRH 169
+L E+S+ LP N++R+ V ++++ SR++ F ++H
Sbjct: 394 ERLVAEQSVHCLPATCFEYPNFIRVVITVPEVMMLEACSRIQEFCEQH 441
>sp|Q54K95|ATTY_DICDI Tyrosine aminotransferase OS=Dictyostelium discoideum
GN=tat PE=3 SV=1
Length = 417
Score = 242 bits (615), Expect = 9e-063
Identities = 135/423 (31%), Positives = 234/423 (55%), Gaps = 18/423 (4%)
Frame = -2
Query: 1404 IGAKRWNFGANEVVERSSSLSIREYLNTLISNLNKG-----DTRSVIALGHGDPSPFPRF 1240
+ ++WN SS S N + ++KG +S I+L GDP F
Sbjct: 5 VSQRKWNV--------ESSKSANNAFNPIRRIVDKGGFKPNPNKSTISLSIGDPCVFGNL 56
Query: 1239 STDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLSYQISPNDVHITCGCLQ 1060
+ A + + + S+KFN Y ++G +AR+AVA+Y+ S +++ D+ + G
Sbjct: 57 NILDYANDLLIENIKSSKFNGYPPSTGYEIAREAVAKYVETPTS-KLTSKDIIVASGASG 115
Query: 1059 AIEILLSSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLLPENGWDVDLDAVEALAD 880
AIE+ + L G NIL+P+P +P+Y+ + + +++++LL + G++VDL+ + +L D
Sbjct: 116 AIELAIGVLLNEGDNILVPKPGFPLYECTSKTKFINVKHYNLLEKQGFNVDLEHLRSLID 175
Query: 879 DKTIAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEVYDHYAFGDKPFVSMAEF 700
DKT AI+V NP NPCG V+S+QHL I + A + + +IADE+Y FG+ F MA
Sbjct: 176 DKTKAILVNNPSNPCGIVYSKQHLLDIIQVAREYCLPIIADEIYSDLTFGEHKFYPMASL 235
Query: 699 AEIVPVVLLGAISKRWFVPGWRLGWMVTLDPHSIMKDSGFLQSLTNVINISTDAATFVQG 520
+ VP++ +G I+KR+ VPGWRLGW+ D +I + ++ L ++ + + VQ
Sbjct: 236 TDKVPILSIGGIAKRFLVPGWRLGWVAIHDRDNIFSNGRIIEGLISLSQVILGPNSLVQS 295
Query: 519 AIPDILG--NTK-EEFFSLKLETVRECAEICYEEIMKIPCITCPSKPEGSMFTMVKLNLS 349
+P +L NT+ +E+ S +T+ +++ + + K + P G+M+ M++++ S
Sbjct: 296 ILPKLLDPQNTQVKEWCSTITKTLESHSKLTVDMLSKANGLK-PVCSSGTMYQMIEIDCS 354
Query: 348 LLGDISDDLDFCCKLAKEESLIILPGRAVGLENWLRITFAVELDLLIDGFSRLKNFAQRH 169
DI+DD +F KL +E+S+ +L G L N+ RI F +D L + + R+ F + H
Sbjct: 355 KYEDIADDNEFVGKLLEEQSVFLLQGTVFSLPNFFRIVFCAPIDKLTEAYERIIEFCETH 414
Query: 168 SKK 160
KK
Sbjct: 415 KKK 417
>sp|P33447|ATTY_TRYCR Tyrosine aminotransferase OS=Trypanosoma cruzi PE=1 SV=2
Length = 416
Score = 213 bits (542), Expect = 3e-054
Identities = 125/386 (32%), Positives = 202/386 (52%), Gaps = 15/386 (3%)
Frame = -2
Query: 1290 RSVIALGHGDPSPFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYL---- 1123
+ +I L GDP+ T + +K + +A+ S + N Y G P AR+AVA +
Sbjct: 33 KPIIKLSVGDPTLDKNLLTSAAQIKKLKEAIDSQECNGYFPTVGSPEAREAVATWWRNSF 92
Query: 1122 --SRDLSYQISPNDVHITCGCLQAIEILLSSLAKPGANILLPRPTYPMYDSRASFSQLEI 949
+L I ++V + G I + ++++ G L+P+P +P Y++ + +
Sbjct: 93 VHKEELKSTIVKDNVVLCSGGSHGILMAITAICDAGDYALVPQPGFPHYETVCKAYGIGM 152
Query: 948 RYFDLLPENGWDVDLDAVEALADDKTIAIVVVNPCNPCGNVFSRQHLQKIAETACKLGIL 769
+++ PEN W+ DLD + L DDKT ++V NP NPCG+ FSR+H++ I A +L +
Sbjct: 153 HFYNCRPENDWEADLDEIRRLKDDKTKLLIVTNPSNPCGSNFSRKHVEDIVRLAEELRLP 212
Query: 768 LIADEVYDHYAFGDK----PFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMVTLDPHS 601
L +DE+Y F K F S+A+F VP V+LG +K VPGWRLGW++ +DPH
Sbjct: 213 LFSDEIYAGMVFKGKDPNATFTSVADFETTVPRVILGGTAKNLVVPGWRLGWLLYVDPHG 272
Query: 600 IMKDSGFLQSLTNVINISTDAATFVQGAIPDILGNTKEEFFSLKLETVRECAEICYEEIM 421
FL+ L V + T VQ A+ + L NT +E + + E A Y I
Sbjct: 273 --NGPSFLEGLKRVGMLVCGPCTVVQAALGEALLNTPQEHLDQIVAKIEESAMYLYNHIG 330
Query: 420 KIPCI-TCPSKPEGSMFTMVKLNLSLLGDISDDLDFCCKLAKEESLIILPGRAVGLENWL 244
+ CI P+ P G+M+ M +++L DI D++F KL +EE++ +LPG +
Sbjct: 331 E--CIGLAPTMPRGAMYLMSRIDLEKYRDIKTDVEFFEKLLEEENVQVLPGTIFHAPGFT 388
Query: 243 RITFAVELDLLIDGFSRLKNFAQRHS 166
R+T +++ + R+K F QRH+
Sbjct: 389 RLTTTRPVEVYREAVERIKAFCQRHA 414
>sp|O67781|AAT_AQUAE Aspartate aminotransferase OS=Aquifex aeolicus GN=aspC PE=3
SV=1
Length = 394
Score = 135 bits (339), Expect = 9e-031
Identities = 93/314 (29%), Positives = 159/314 (50%), Gaps = 30/314 (9%)
Frame = -2
Query: 1284 VIALGHGDPSPFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLSY 1105
VI G G+P F T P +K C YA ++GIP R+A+AE L ++
Sbjct: 34 VIGFGAGEPD----FDT-PDFIKEACIRALREGKTKYAPSAGIPELREAIAEKLLKENKV 88
Query: 1104 QISPNDVHITCGCLQAIEILLSSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLLP- 928
+ P+++ ++ G + ++ ++ G +LLP P + Y +IR+F +P
Sbjct: 89 EYKPSEIVVSAGAKMVLFLIFMAILDEGDEVLLPSPYWVTYPE-------QIRFFGGVPV 141
Query: 927 ------ENGWDVDLDAVEALADDKTIAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILL 766
E G+ + L+ V+ ++T AIV+ +P NP G V+ + L+KIAE + GI +
Sbjct: 142 EVPLKKEKGFQLSLEDVKEKVTERTKAIVINSPNNPTGAVYEEEELKKIAEFCVERGIFI 201
Query: 765 IADEVYDHYAFGDKPFVSMAEFAEIVPVV--LLGAISKRWFVPGWRLGWMVTLDPHSIMK 592
I+DE Y+++ +GD FVS A F++ V + + A SK + + GWR+G++ + ++ +
Sbjct: 202 ISDECYEYFVYGDAKFVSPASFSDEVKNITFTVNAFSKSYSMTGWRIGYVACPEEYAKVI 261
Query: 591 DSGFLQSLTNVINISTDAATFVQGAIPDILGNTKEEFFSLKLETVRE-CAEICYEEIMKI 415
S QS++NV TF Q + L N K + F ++ E + EE+ KI
Sbjct: 262 ASLNSQSVSNV-------TTFAQYGALEALKNPKSKDFVNEMRNAFERRRDTAVEELSKI 314
Query: 414 PCITCPSKPEGSMF 373
P + KPEG+ +
Sbjct: 315 PGMDV-VKPEGAFY 327
>sp|P0A960|YFBQ_ECOL6 Uncharacterized aminotransferase yfbQ OS=Escherichia coli
O6 GN=yfbQ PE=3 SV=1
Length = 405
Score = 130 bits (326), Expect = 3e-029
Identities = 94/347 (27%), Positives = 164/347 (47%), Gaps = 11/347 (3%)
Frame = -2
Query: 1284 VIALGHGDPSPFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLSY 1105
V+ L G+P+PF + D V I + ++ Y + G+ ARKA+ ++
Sbjct: 35 VLKLNIGNPAPFGFDAPDEILVDVIRNLPTA---QGYCDSKGLYSARKAIMQHYQARGMR 91
Query: 1104 QISPNDVHITCGCLQAIEILLSSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLLPE 925
++ D++I G + I + +L G +L+P P YP++ + S S + ++
Sbjct: 92 DVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDES 151
Query: 924 NGWDVDLDAVEALADDKTIAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEVYD 745
+ W DLD + A +T IV++NP NP G V+S++ L +I E A + +++ ADE+YD
Sbjct: 152 SDWFPDLDDIRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYD 211
Query: 744 HYAFGDKPFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMVTLDPHSIMKDSGFLQSLT 565
+ D S+A A + + +SK + V G+R GWMV P K G+++ L
Sbjct: 212 KILYDDAEHHSIAPLAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAK--GYIEGLE 269
Query: 564 NVINISTDAATFVQGAIPDILGNTKE-EFFSLKLETVRECAEICYEEIMKIPCITCPSKP 388
+ ++ A Q AI LG + F + E +E I IP ++C KP
Sbjct: 270 MLASMRLCANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDIPGVSC-VKP 328
Query: 387 EGSMFTMVKLNLSLLGDISDDLDFCCKLAKEESLIILPGRAVGLENW 247
G+++ K++ +I DD +E ++++ G A NW
Sbjct: 329 RGALYMFPKIDAKRF-NIHDDQKMVLDFLLQEKVLLVQGTAF---NW 371
>sp|P0A959|YFBQ_ECOLI Uncharacterized aminotransferase yfbQ OS=Escherichia coli
(strain K12) GN=yfbQ PE=1 SV=1
Length = 405
Score = 130 bits (326), Expect = 3e-029
Identities = 94/347 (27%), Positives = 164/347 (47%), Gaps = 11/347 (3%)
Frame = -2
Query: 1284 VIALGHGDPSPFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLSY 1105
V+ L G+P+PF + D V I + ++ Y + G+ ARKA+ ++
Sbjct: 35 VLKLNIGNPAPFGFDAPDEILVDVIRNLPTA---QGYCDSKGLYSARKAIMQHYQARGMR 91
Query: 1104 QISPNDVHITCGCLQAIEILLSSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLLPE 925
++ D++I G + I + +L G +L+P P YP++ + S S + ++
Sbjct: 92 DVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDES 151
Query: 924 NGWDVDLDAVEALADDKTIAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEVYD 745
+ W DLD + A +T IV++NP NP G V+S++ L +I E A + +++ ADE+YD
Sbjct: 152 SDWFPDLDDIRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYD 211
Query: 744 HYAFGDKPFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMVTLDPHSIMKDSGFLQSLT 565
+ D S+A A + + +SK + V G+R GWMV P K G+++ L
Sbjct: 212 KILYDDAEHHSIAPLAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAK--GYIEGLE 269
Query: 564 NVINISTDAATFVQGAIPDILGNTKE-EFFSLKLETVRECAEICYEEIMKIPCITCPSKP 388
+ ++ A Q AI LG + F + E +E I IP ++C KP
Sbjct: 270 MLASMRLCANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDIPGVSC-VKP 328
Query: 387 EGSMFTMVKLNLSLLGDISDDLDFCCKLAKEESLIILPGRAVGLENW 247
G+++ K++ +I DD +E ++++ G A NW
Sbjct: 329 RGALYMFPKIDAKRF-NIHDDQKMVLDFLLQEKVLLVQGTAF---NW 371
>sp|P0A961|YFBQ_SHIFL Uncharacterized aminotransferase yfbQ OS=Shigella flexneri
GN=yfbQ PE=3 SV=1
Length = 405
Score = 130 bits (326), Expect = 3e-029
Identities = 94/347 (27%), Positives = 164/347 (47%), Gaps = 11/347 (3%)
Frame = -2
Query: 1284 VIALGHGDPSPFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLSY 1105
V+ L G+P+PF + D V I + ++ Y + G+ ARKA+ ++
Sbjct: 35 VLKLNIGNPAPFGFDAPDEILVDVIRNLPTA---QGYCDSKGLYSARKAIMQHYQARGMR 91
Query: 1104 QISPNDVHITCGCLQAIEILLSSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLLPE 925
++ D++I G + I + +L G +L+P P YP++ + S S + ++
Sbjct: 92 DVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDES 151
Query: 924 NGWDVDLDAVEALADDKTIAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEVYD 745
+ W DLD + A +T IV++NP NP G V+S++ L +I E A + +++ ADE+YD
Sbjct: 152 SDWFPDLDDIRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYD 211
Query: 744 HYAFGDKPFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMVTLDPHSIMKDSGFLQSLT 565
+ D S+A A + + +SK + V G+R GWMV P K G+++ L
Sbjct: 212 KILYDDAEHHSIAPLAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAK--GYIEGLE 269
Query: 564 NVINISTDAATFVQGAIPDILGNTKE-EFFSLKLETVRECAEICYEEIMKIPCITCPSKP 388
+ ++ A Q AI LG + F + E +E I IP ++C KP
Sbjct: 270 MLASMRLCANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDIPGVSC-VKP 328
Query: 387 EGSMFTMVKLNLSLLGDISDDLDFCCKLAKEESLIILPGRAVGLENW 247
G+++ K++ +I DD +E ++++ G A NW
Sbjct: 329 RGALYMFPKIDAKRF-NIHDDQKMVLDFLLQEKVLLVQGTAF---NW 371
>sp|Q60317|AAT1_METJA Probable aspartate aminotransferase 1
OS=Methanocaldococcus jannaschii GN=MJ0001 PE=3 SV=1
Length = 375
Score = 117 bits (292), Expect = 2e-025
Identities = 74/270 (27%), Positives = 141/270 (52%), Gaps = 14/270 (5%)
Frame = -2
Query: 1293 TRSVIALGHGDPSPFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRD 1114
T I LG G+P F T ++A A+ K +Y+ +GIP R+ ++ L D
Sbjct: 22 TSDCINLGIGEPD----FDTPKHIIEAAKRALDEGK-THYSPNNGIPELREEISNKLKDD 76
Query: 1113 LSYQISPNDVHITCGCLQAIEILLSSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDL 934
+ + +++ +TCG +A+ + + +L G +L+P P++ Y S F++ +I+ DL
Sbjct: 77 YNLDVDKDNIIVTCGASEALMLSIMTLIDRGDEVLIPNPSFVSYFSLTEFAEGKIKNIDL 136
Query: 933 LPENGWDVDLDAVEALADDKTIAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADE 754
+ +++DL+ V+ KT I+ +P NP G V+ ++ ++ +AE A +++++DE
Sbjct: 137 --DENFNIDLEKVKESITKKTKLIIFNSPSNPTGKVYDKETIKGLAEIAEDYNLIIVSDE 194
Query: 753 VYDHYAFGDKPFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMVTLDPHSIMKDSGFLQ 574
VYD + DK S +F + +L+ SK + + GWR+G++ D + K+ +
Sbjct: 195 VYDKIIY-DKKHYSPMQFTD--RCILINGFSKTYAMTGWRIGYLAVSD--ELNKELDLIN 249
Query: 573 SLTNVINIS-TDAATFVQ-GAIPDILGNTK 490
++ + S A TF Q GA+ + G+ K
Sbjct: 250 NMIKIHQYSFACATTFAQYGALAALRGSQK 279
>sp|Q9V0L2|AAT_PYRAB Aspartate aminotransferase OS=Pyrococcus abyssi GN=aspC
PE=3 SV=1
Length = 389
Score = 107 bits (267), Expect = 2e-022
Identities = 65/228 (28%), Positives = 121/228 (53%), Gaps = 13/228 (5%)
Frame = -2
Query: 1290 RSVIALGHGDPSPFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDL 1111
+ VI+LG G+P F T P +K +Y G+P R+A+AE L +
Sbjct: 26 KDVISLGIGEPD----FDT-PQHIKEYAKEALDMGLTHYGPNIGLPELREAIAEKLKKQN 80
Query: 1110 SYQISPN-DVHITCGCLQAIEILLSSLAKPGANILLPRPTYPMYDSR---ASFSQLEIRY 943
+ + PN ++ + G QA + LS+ K G +L+P P + Y A +E+
Sbjct: 81 NIEADPNKEIMVLVGANQAFLMGLSAFLKDGEEVLIPTPAFVSYAPAVILAGGKPVEVPT 140
Query: 942 FDLLPENGWDVDLDAVEALADDKTIAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLI 763
++ EN + +++D ++ +KT A+++ +PCNP G+V ++ L++IA+ A + +++I
Sbjct: 141 YE---ENEFRLNVDELKKYVTEKTKALIINSPCNPTGSVLKKKDLEEIADFAVEHDLIVI 197
Query: 762 ADEVYDHYAFGDKPFVSMAEFAEIVP-VVLLGAISKRWFVPGWRLGWM 622
+DEVY+H+ + D S+A + + + SK + + GWRLG++
Sbjct: 198 SDEVYEHFIYDDVKHYSIASLDGMFERTITVNGFSKTFAMTGWRLGFV 245
>sp|P52892|ALAT_YEAST Probable alanine aminotransferase OS=Saccharomyces
cerevisiae GN=ALT2 PE=1 SV=1
Length = 507
Score = 101 bits (249), Expect = 2e-020
Identities = 63/202 (31%), Positives = 102/202 (50%), Gaps = 12/202 (5%)
Frame = -2
Query: 1284 VIALGHGDPSPFPRFSTD--PSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLS-RD 1114
++ +GH + + FS D A + + D S Y+ + G+P R+ VA++++ RD
Sbjct: 100 ILRVGHNELASLNLFSRDALERAERLLNDIGGS--IGAYSHSQGVPGIRQTVADFITRRD 157
Query: 1113 LSYQISPNDVHITCGCLQAIEILLSSLAKPG-ANILLPRPTYPMYDSRASFSQLEIRYFD 937
+P D+++T G A LLS L K +L+P P YP+Y + AS ++ +
Sbjct: 158 GGEPATPEDIYLTTGASSAATSLLSLLCKDSQTGLLIPIPQYPLYTASASLFNAQVLPYY 217
Query: 936 LLPENGWDVDLDAVEALADD------KTIAIVVVNPCNPCGNVFSRQHLQKIAETACKLG 775
L E+ W + D +E + D + ++V+NP NP G V S + + +I A K G
Sbjct: 218 LDEESNWSTNSDEIEKVVQDALKKQIRPSVLIVINPGNPTGAVLSEETIARICLIAAKYG 277
Query: 774 ILLIADEVYDHYAFGDKPFVSM 709
I +I+DEVY F D F SM
Sbjct: 278 ITIISDEVYQENIFNDVKFHSM 299
>sp|P52893|ALAM_YEAST Probable alanine aminotransferase, mitochondrial
OS=Saccharomyces cerevisiae GN=ALT1 PE=1 SV=1
Length = 592
Score = 94 bits (232), Expect = 2e-018
Identities = 54/164 (32%), Positives = 88/164 (53%), Gaps = 8/164 (4%)
Frame = -2
Query: 1176 YASASGIPVARKAVAEYLSRDLSYQIS-PNDVHITCGCLQAIEILLSSLAK-PGANILLP 1003
Y+S+ G+ RK+VAE++++ +IS P D+ +T G A+ LLS + P +L+P
Sbjct: 221 YSSSQGVEGIRKSVAEFITKRDEGEISYPEDIFLTAGASAAVNYLLSIFCRGPETGVLIP 280
Query: 1002 RPTYPMYDSRASFSQLEIRYFDLLPENGWDVDLDAVEALADD------KTIAIVVVNPCN 841
P YP+Y + + + + + L +GW + + +E + + K +VV+NP N
Sbjct: 281 IPQYPLYTATLALNNSQALPYYLDENSGWSTNPEEIETVVKEAIQNEIKPTVLVVINPGN 340
Query: 840 PCGNVFSRQHLQKIAETACKLGILLIADEVYDHYAFGDKPFVSM 709
P G V S + + +I E A K G ++IADEVY F F SM
Sbjct: 341 PTGAVLSPESIAQIFEVAAKYGTVVIADEVYQENIFPGTKFHSM 384
>sp|Q8GYY0|1A112_ARATH Probable aminotransferase ACS12 OS=Arabidopsis thaliana
GN=ACS12 PE=2 SV=2
Length = 495
Score = 88 bits (217), Expect = 1e-016
Identities = 64/197 (32%), Positives = 99/197 (50%), Gaps = 14/197 (7%)
Frame = -2
Query: 1176 YASASGIPVARKAVAEYLSRDLSYQIS--PNDVHITCGCLQAIEILLSSLAKPGANILLP 1003
Y G+ R A A+++SR + +S P+++ IT G AIE+L LA G L+P
Sbjct: 148 YKPFEGLLELRVAFADFMSRIMGGNVSFDPSNMVITAGGTPAIEVLAFCLADHGNAFLIP 207
Query: 1002 RPTYPMYDSRASF-SQLEIRYFDLLPENGWDVDLDAVEALAD------DKTIAIVVVNPC 844
P YP +D F + +E+ + + V + A+E + K I+ NP
Sbjct: 208 TPYYPGFDRDIKFRTGVELIPVHCRSSDNFTVTVSALEQALNQARKRGSKVSGILFSNPS 267
Query: 843 NPCGNVFSRQHLQKIAETACKLGILLIADEVYDHYAFGDKPFVSMAEFA-----EIVPVV 679
NP GN+ SR+ L I A + I +I+DE++ +GDK FVSMAE A + V
Sbjct: 268 NPVGNILSRETLCDILRFAQEKNIHVISDEIFAGSVYGDKEFVSMAEIAGSGEFDKTRVH 327
Query: 678 LLGAISKRWFVPGWRLG 628
++ +SK +PG+R G
Sbjct: 328 IIYGLSKDLSIPGFRAG 344
>sp|Q7NDX4|DAPAT_GLOVI LL-diaminopimelate aminotransferase OS=Gloeobacter
violaceus GN=dapL PE=1 SV=1
Length = 392
Score = 81 bits (199), Expect = 2e-014
Identities = 64/226 (28%), Positives = 98/226 (43%), Gaps = 9/226 (3%)
Frame = -2
Query: 1284 VIALGHGDPSPFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLSY 1105
+I +G GDP T P ++A+ A+ +NY G R+A A + R
Sbjct: 32 IINMGIGDPDK----PTPPVVLEAMHAAIDDPSTHNYPPYKGTKAYREAAAAWFERRFGV 87
Query: 1104 QISPNDVHI--TCGCLQAIEILLSSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLL 931
D + + G +AI + PG L+P P YP+Y + F+ E LL
Sbjct: 88 GGFHPDTEVISSIGSKEAIHNTFLAFVDPGDYTLIPDPAYPVYRTSTIFAGGEFFAMPLL 147
Query: 930 PENGWDVDLDAVEALADDKTIAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEV 751
PEN DL+AV K + + P NP G V S + +K+ A K IL+ D
Sbjct: 148 PENQLLPDLEAVPETVARKAKLLWLNYPNNPTGAVASLEFFEKVVHFAKKHDILVCHDNA 207
Query: 750 YDHYAFG--DKPFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMV 619
Y A+ P + A V + L + SK + + GWR+G+++
Sbjct: 208 YSEMAYDGYKPPSILQVPGARDVAIEFL-SCSKAYNMTGWRVGFVI 252
>sp|Q30ZX9|DAPAT_DESDG LL-diaminopimelate aminotransferase OS=Desulfovibrio
desulfuricans (strain G20) GN=dapL PE=3 SV=1
Length = 388
Score = 79 bits (193), Expect = 7e-014
Identities = 60/226 (26%), Positives = 103/226 (45%), Gaps = 9/226 (3%)
Frame = -2
Query: 1284 VIALGHGDPS-PFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLS 1108
+I+LG GDP P P F ++A+ A + Y S +G+ R+ VA + R +
Sbjct: 35 IISLGIGDPDMPTPDF-----VIEALKKAAEKPANHQYPSYTGMLAFRQEVANWYKRRYA 89
Query: 1107 YQISP-NDVHITCGCLQAIEILLSSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLL 931
++ P +V G + I ++ PG +L+ P YP+Y + F ++ LL
Sbjct: 90 VELDPKTEVLTLIGSKEGIAHFPTAFVNPGDLVLVCPPCYPVYAIASRFMGGVVQELPLL 149
Query: 930 PENGWDVDLDAVEALADDKTIAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEV 751
EN + DLDAV+ +K I V P NP + R +K+ A K ++++ D
Sbjct: 150 EENDFLPDLDAVDEATWEKARCIFVNYPNNPTAAMAPRSFFEKLIGIARKHNVIVVHDAA 209
Query: 750 YD--HYAFGDKPFVSMAEFAEIVPVVLLGAISKRWFVPGWRLGWMV 619
Y +Y ++P M + + ++SK + + GWR+ V
Sbjct: 210 YTEMYYNENNRPLSIMEIPGAMDVAIEFNSLSKPYNMTGWRIAMAV 255
>sp|B8DJJ6|DAPAT_DESVM LL-diaminopimelate aminotransferase OS=Desulfovibrio
vulgaris (strain Miyazaki F / DSM 19637) GN=dapL PE=3 SV=1
Length = 389
Score = 79 bits (192), Expect = 1e-013
Identities = 65/227 (28%), Positives = 102/227 (44%), Gaps = 11/227 (4%)
Frame = -2
Query: 1284 VIALGHGDPS-PFPRFSTDPSAVKAICDAVSSNKFNNYASASGIPVARKAVAEYLSRDLS 1108
+I+LG GDP P P F ++A+ AV + Y S G+ R+ VA + R
Sbjct: 35 IISLGIGDPDMPTPDF-----IIEAMKKAVERPANHQYPSYVGMLEFRQEVANWYGRRFG 89
Query: 1107 YQISP-NDVHITCGCLQAIEILLSSLAKPGANILLPRPTYPMYDSRASFSQLEIRYFDLL 931
+ P +V G + I + PG +L+ P YP+Y F E+++ L+
Sbjct: 90 VSLDPKTEVIGLIGSKEGIAHFPLAFVNPGDLVLVCTPNYPVYHIATGFVGGEVQFIPLV 149
Query: 930 PENGWDVDLDAVEALADDKTIAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEV 751
EN + DLDA+ A D+ I V P NP R +K+ K +++ D
Sbjct: 150 EENDYLPDLDAIPAATWDRAKMIFVNYPNNPTAATAPRAFYEKLIGICRKHNVIIAHDTA 209
Query: 750 YD--HYAFGDKPFVSMAEFAEIVPVVL-LGAISKRWFVPGWRLGWMV 619
Y +Y DKP +S+ E V + ++SK + + GWR+G V
Sbjct: 210 YTEVYYDENDKP-MSILEVEGAKDVTIEFHSLSKTYNMTGWRVGMAV 255
>sp|P47039|BNA3_YEAST Probable kynurenine--oxoglutarate transaminase BNA3
OS=Saccharomyces cerevisiae GN=BNA3 PE=1 SV=1
Length = 444
Score = 71 bits (173), Expect = 2e-011
Identities = 36/105 (34%), Positives = 60/105 (57%), Gaps = 3/105 (2%)
Frame = -2
Query: 918 WDVDLDAVEALADDKTIAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEVYDHY 739
W +D + E KT A+++ P NP G VF+R+ L + K +++I+DEVY+H
Sbjct: 184 WTIDFEQFEKAITSKTKAVIINTPHNPIGKVFTREELTTLGNICVKHNVVIISDEVYEHL 243
Query: 738 AFGDKPFVSMAEFA-EIVPVVL-LGAISKRWFVPGWRLGWMVTLD 610
F D F +A + EI + L +G+ K + GWR+GW+++L+
Sbjct: 244 YFTDS-FTRIATLSPEIGQLTLTVGSAGKSFAATGWRIGWVLSLN 287
>sp|O14209|YDT4_SCHPO Uncharacterized aminotransferase C6B12.04c
OS=Schizosaccharomyces pombe GN=SPAC6B12.04c PE=2 SV=1
Length = 421
Score = 70 bits (171), Expect = 3e-011
Identities = 36/102 (35%), Positives = 58/102 (56%), Gaps = 4/102 (3%)
Frame = -2
Query: 918 WDVDLDAVEALADDKTIAIVVVNPCNPCGNVFSRQHLQKIAETACKLGILLIADEVYDHY 739
W +D++ + +KT IV+ P NP G +FS + L +IA+ K +L+++DEVYD
Sbjct: 163 WKLDMNKLRNAITEKTKMIVINTPHNPLGKIFSEEELNEIADLVLKHNLLVVSDEVYDRL 222
Query: 738 AFGDKPFVSMAEFAE--IVPVVLLGAISKRWFVPGWRLGWMV 619
+F PFV +A VV +G+ K + GWR+GW++
Sbjct: 223 SF--VPFVRLATLRPELFKHVVTVGSGGKTFGCTGWRVGWLI 262
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,533,745,664
Number of Sequences: 518415
Number of Extensions: 12533745664
Number of Successful Extensions: 80211091
Number of sequences better than 0.0: 0
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