BLASTX 7.6.2
Query= UN03477 /QuerySize=937
(936 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9LDU6|ST7R_ARATH 7-dehydrocholesterol reductase OS=Arabidops... 463 1e-129
sp|Q6P4M0|DHCR7_XENTR 7-dehydrocholesterol reductase OS=Xenopus ... 221 5e-057
sp|Q7ZXH1|DHCR7_XENLA 7-dehydrocholesterol reductase OS=Xenopus ... 220 1e-056
sp|Q5E9J5|DHCR7_BOVIN 7-dehydrocholesterol reductase OS=Bos taur... 212 4e-054
sp|O88455|DHCR7_MOUSE 7-dehydrocholesterol reductase OS=Mus musc... 211 5e-054
sp|Q9Z2Z8|DHCR7_RAT 7-dehydrocholesterol reductase OS=Rattus nor... 210 1e-053
sp|Q9UBM7|DHCR7_HUMAN 7-dehydrocholesterol reductase OS=Homo sap... 210 2e-053
sp|Q7SXF1|DHCR7_DANRE 7-dehydrocholesterol reductase OS=Danio re... 210 2e-053
sp|Q5UQI4|DHCR7_MIMIV Probable 7-dehydrocholesterol reductase OS... 176 3e-043
sp|Q54PP1|ERG24_DICDI Delta(14)-sterol reductase OS=Dictyosteliu... 118 6e-026
sp|O08984|LBR_RAT Lamin-B receptor OS=Rattus norvegicus GN=Lbr P... 106 4e-022
sp|Q3U9G9|LBR_MOUSE Lamin-B receptor OS=Mus musculus GN=Lbr PE=1... 105 5e-022
sp|Q14739|LBR_HUMAN Lamin-B receptor OS=Homo sapiens GN=LBR PE=1... 105 7e-022
sp|Q09195|ERG24_SCHPO Delta(14)-sterol reductase OS=Schizosaccha... 104 9e-022
sp|Q5R7H4|LBR_PONAB Lamin-B receptor OS=Pongo abelii GN=LBR PE=2... 103 2e-021
sp|Q71KT5|ERG24_MOUSE Delta(14)-sterol reductase OS=Mus musculus... 102 6e-021
sp|Q8WMV1|ERG24_BOVIN Delta(14)-sterol reductase OS=Bos taurus G... 97 1e-019
sp|P78575|ERG24_ASCIM Delta(14)-sterol reductase OS=Ascobolus im... 97 1e-019
sp|O76062|ERG24_HUMAN Delta(14)-sterol reductase OS=Homo sapiens... 97 1e-019
sp|P23913|LBR_CHICK Lamin-B receptor OS=Gallus gallus GN=LBR PE=... 90 2e-017
>sp|Q9LDU6|ST7R_ARATH 7-dehydrocholesterol reductase OS=Arabidopsis thaliana
GN=DWF5 PE=1 SV=1
Length = 432
Score = 463 bits (1190), Expect = 1e-129
Identities = 211/221 (95%), Positives = 217/221 (98%)
Frame = -2
Query: 935 YCIKQYEINGKVSDSMLVNTILMLVYVTKFFWWEAGYWNTMDIAHDRAGFYICWGCLVWV 756
YCIKQYEINGKVSDSMLVNTILMLVYVTKFFWWEAGYWNTMDIAHDRAGFYICWGCLVWV
Sbjct: 212 YCIKQYEINGKVSDSMLVNTILMLVYVTKFFWWEAGYWNTMDIAHDRAGFYICWGCLVWV 271
Query: 755 PSIYTSPGMYLVNHPVQLGTQLAIYILVAGCLCIYINYDCDRQRQEFRRTNGKCSVWGKA 576
PS+YTSPGMYLVNHPV+LGTQLAIYILVAG LCIYINYDCDRQRQEFRRTNGKC VWG+A
Sbjct: 272 PSVYTSPGMYLVNHPVELGTQLAIYILVAGILCIYINYDCDRQRQEFRRTNGKCLVWGRA 331
Query: 575 PSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTVPALFDNFLPYFYVI 396
PSKIVA+YTTT+GETKTSLLLTSGWWGLARHFHYVPEI SAFFWTVPALFDNFL YFYVI
Sbjct: 332 PSKIVASYTTTSGETKTSLLLTSGWWGLARHFHYVPEILSAFFWTVPALFDNFLAYFYVI 391
Query: 395 FLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
FLT+LLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY
Sbjct: 392 FLTLLLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 432
>sp|Q6P4M0|DHCR7_XENTR 7-dehydrocholesterol reductase OS=Xenopus tropicalis
GN=dhcr7 PE=2 SV=1
Length = 473
Score = 221 bits (563), Expect = 5e-057
Identities = 99/221 (44%), Positives = 144/221 (65%)
Frame = -2
Query: 935 YCIKQYEINGKVSDSMLVNTILMLVYVTKFFWWEAGYWNTMDIAHDRAGFYICWGCLVWV 756
Y KQ E+ G+V++SM++ +L +YV FFW E+ Y T+DI HD G+Y+ WG VW+
Sbjct: 253 YAAKQQELYGQVTNSMILVNVLQAIYVVDFFWNESWYLKTIDICHDHFGWYLGWGDCVWL 312
Query: 755 PSIYTSPGMYLVNHPVQLGTQLAIYILVAGCLCIYINYDCDRQRQEFRRTNGKCSVWGKA 576
P +YT G+YLV +PV+L T A+ +L+ G + YI + Q+ FRRTNG C +WGK
Sbjct: 313 PYLYTLQGLYLVYNPVELSTATAVGVLLLGLIGYYIFRMTNHQKDLFRRTNGNCKIWGKK 372
Query: 575 PSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTVPALFDNFLPYFYVI 396
P I +YT+ G+ S L+ SG+WG+ARH +Y ++ + + + FD+ LPYFY
Sbjct: 373 PKSIECSYTSADGKRHYSKLMISGFWGVARHLNYTGDLMGSLAYCLACGFDHLLPYFYFT 432
Query: 395 FLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
++TILL R RD+ RC SKYGK WKLY + V YR++PG++
Sbjct: 433 YMTILLVHRCIRDEHRCSSKYGKDWKLYTDAVPYRLLPGLF 473
>sp|Q7ZXH1|DHCR7_XENLA 7-dehydrocholesterol reductase OS=Xenopus laevis GN=dhcr7
PE=2 SV=1
Length = 473
Score = 220 bits (559), Expect = 1e-056
Identities = 99/221 (44%), Positives = 142/221 (64%)
Frame = -2
Query: 935 YCIKQYEINGKVSDSMLVNTILMLVYVTKFFWWEAGYWNTMDIAHDRAGFYICWGCLVWV 756
Y KQ E+ G+V++SM++ +L +YV FFW E+ Y T+DI HD G+Y+ WG VW+
Sbjct: 253 YAAKQQELYGQVTNSMILVNVLQAIYVVDFFWNESWYLKTIDICHDHFGWYLGWGDCVWL 312
Query: 755 PSIYTSPGMYLVNHPVQLGTQLAIYILVAGCLCIYINYDCDRQRQEFRRTNGKCSVWGKA 576
P +YT G+YLV +PV+L T A+ +L+ G + YI + Q+ FRRTNG C +WGK
Sbjct: 313 PYLYTLQGLYLVYNPVELSTTAAVAVLLLGLIGYYIFRMTNHQKDLFRRTNGNCKIWGKK 372
Query: 575 PSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTVPALFDNFLPYFYVI 396
P I Y + G+ S L+ SG+WG+ARH +Y ++ + + + FD+ LPYFY I
Sbjct: 373 PKSIECFYVSADGKRHYSKLMISGFWGVARHLNYTGDLMGSLAYCLACGFDHLLPYFYFI 432
Query: 395 FLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
++TILL R RD+ RC SKYGK WKLY V YR++PG++
Sbjct: 433 YMTILLVHRCIRDEHRCSSKYGKDWKLYTSAVPYRLLPGLF 473
>sp|Q5E9J5|DHCR7_BOVIN 7-dehydrocholesterol reductase OS=Bos taurus GN=DHCR7
PE=2 SV=1
Length = 475
Score = 212 bits (538), Expect = 4e-054
Identities = 98/221 (44%), Positives = 141/221 (63%)
Frame = -2
Query: 935 YCIKQYEINGKVSDSMLVNTILMLVYVTKFFWWEAGYWNTMDIAHDRAGFYICWGCLVWV 756
+ KQ E+ G V++SM++ IL +YV FFW E Y T+DI HD G+Y+ WG VW+
Sbjct: 255 FAAKQQELYGHVTNSMVLVNILQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWGDCVWL 314
Query: 755 PSIYTSPGMYLVNHPVQLGTQLAIYILVAGCLCIYINYDCDRQRQEFRRTNGKCSVWGKA 576
P +YT G+YLV HPVQL T A+ +L+ G L YI + Q+ FRRT+G+C +WG+
Sbjct: 315 PYLYTLQGLYLVYHPVQLPTYYALGVLLLGLLGYYIFRMTNHQKDLFRRTDGRCLIWGRK 374
Query: 575 PSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTVPALFDNFLPYFYVI 396
P I +YT+ G+ S LL SG+WG+ARHF+Y ++ + + + + LPYFY+I
Sbjct: 375 PKAIECSYTSADGQRHHSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGGGHLLPYFYII 434
Query: 395 FLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
F+ ILL R RD+ RC +KYG+ W+ Y V YR++PGI+
Sbjct: 435 FMAILLTHRCLRDEHRCANKYGRDWEHYTAAVPYRLLPGIF 475
>sp|O88455|DHCR7_MOUSE 7-dehydrocholesterol reductase OS=Mus musculus GN=Dhcr7
PE=2 SV=1
Length = 471
Score = 211 bits (537), Expect = 5e-054
Identities = 98/221 (44%), Positives = 141/221 (63%)
Frame = -2
Query: 935 YCIKQYEINGKVSDSMLVNTILMLVYVTKFFWWEAGYWNTMDIAHDRAGFYICWGCLVWV 756
+ KQ E+ G V++SM++ +L +YV FFW E Y T+DI HD G+Y+ WG VW+
Sbjct: 251 FAAKQQELYGHVTNSMILVNVLQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWGDCVWL 310
Query: 755 PSIYTSPGMYLVNHPVQLGTQLAIYILVAGCLCIYINYDCDRQRQEFRRTNGKCSVWGKA 576
P +YT G+YLV HPVQL T A+ IL+ G + YI + Q+ FRRT+G+C +WGK
Sbjct: 311 PYLYTLQGLYLVYHPVQLSTPNALGILLLGLVGYYIFRMTNHQKDLFRRTDGRCLIWGKK 370
Query: 575 PSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTVPALFDNFLPYFYVI 396
P I +YT+ G S LL SG+WG+ARHF+Y ++ + + + + LPYFY+I
Sbjct: 371 PKAIECSYTSADGLKHHSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGGGHLLPYFYII 430
Query: 395 FLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
++TILL R RD+ RC +KYG+ W+ Y V YR++PGI+
Sbjct: 431 YMTILLTHRCLRDEHRCANKYGRDWERYTAAVPYRLLPGIF 471
>sp|Q9Z2Z8|DHCR7_RAT 7-dehydrocholesterol reductase OS=Rattus norvegicus
GN=Dhcr7 PE=2 SV=1
Length = 471
Score = 210 bits (534), Expect = 1e-053
Identities = 97/221 (43%), Positives = 140/221 (63%)
Frame = -2
Query: 935 YCIKQYEINGKVSDSMLVNTILMLVYVTKFFWWEAGYWNTMDIAHDRAGFYICWGCLVWV 756
+ KQ E+ G V++SM++ +L +YV FFW E Y T+DI HD G+Y+ WG VW+
Sbjct: 251 FAAKQQELYGHVTNSMILVNVLQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWGDCVWL 310
Query: 755 PSIYTSPGMYLVNHPVQLGTQLAIYILVAGCLCIYINYDCDRQRQEFRRTNGKCSVWGKA 576
P +YT G+YLV HPVQL T A+ +L+ G + YI + Q+ FRRT+G C +WGK
Sbjct: 311 PYLYTLQGLYLVYHPVQLSTPNALGVLLLGLVGYYIFRMTNHQKDLFRRTDGHCLIWGKK 370
Query: 575 PSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTVPALFDNFLPYFYVI 396
P I +YT+ G S LL SG+WG+ARHF+Y ++ + + + + LPYFY+I
Sbjct: 371 PKAIECSYTSADGLKHRSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGGGHLLPYFYII 430
Query: 395 FLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
++TILL R RD+ RC +KYG+ W+ Y V YR++PGI+
Sbjct: 431 YMTILLTHRCLRDEHRCANKYGRDWERYVAAVPYRLLPGIF 471
>sp|Q9UBM7|DHCR7_HUMAN 7-dehydrocholesterol reductase OS=Homo sapiens GN=DHCR7
PE=1 SV=1
Length = 475
Score = 210 bits (533), Expect = 2e-053
Identities = 95/221 (42%), Positives = 142/221 (64%)
Frame = -2
Query: 935 YCIKQYEINGKVSDSMLVNTILMLVYVTKFFWWEAGYWNTMDIAHDRAGFYICWGCLVWV 756
+ KQ E++ V+++M++ +L +YV FFW E Y T+DI HD G+Y+ WG VW+
Sbjct: 255 FAAKQRELHSHVTNAMVLVNVLQAIYVIDFFWNETWYLKTIDICHDHFGWYLGWGDCVWL 314
Query: 755 PSIYTSPGMYLVNHPVQLGTQLAIYILVAGCLCIYINYDCDRQRQEFRRTNGKCSVWGKA 576
P +YT G+YLV HPVQL T A+ +L+ G + YI + Q+ FRRT+G+C +WG+
Sbjct: 315 PYLYTLQGLYLVYHPVQLSTPHAVGVLLLGLVGYYIFRVANHQKDLFRRTDGRCLIWGRK 374
Query: 575 PSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTVPALFDNFLPYFYVI 396
P I +YT+ G+ S LL SG+WG+ARHF+YV ++ + + + + LPYFY+I
Sbjct: 375 PKVIECSYTSADGQRHHSKLLVSGFWGVARHFNYVGDLMGSLAYCLACGGGHLLPYFYII 434
Query: 395 FLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
++ ILL R RD+ RC SKYG+ W+ Y V YR++PGI+
Sbjct: 435 YMAILLTHRCLRDEHRCASKYGRDWERYTAAVPYRLLPGIF 475
>sp|Q7SXF1|DHCR7_DANRE 7-dehydrocholesterol reductase OS=Danio rerio GN=dhcr7
PE=2 SV=1
Length = 478
Score = 210 bits (532), Expect = 2e-053
Identities = 97/221 (43%), Positives = 140/221 (63%)
Frame = -2
Query: 935 YCIKQYEINGKVSDSMLVNTILMLVYVTKFFWWEAGYWNTMDIAHDRAGFYICWGCLVWV 756
Y KQ E+ G V++SM++ +L VYV FFW EA Y T+DI HD G+Y+ WG VW+
Sbjct: 258 YAAKQQELYGYVTNSMILVNVLQAVYVVDFFWNEAWYLKTIDICHDHFGWYLGWGDCVWL 317
Query: 755 PSIYTSPGMYLVNHPVQLGTQLAIYILVAGCLCIYINYDCDRQRQEFRRTNGKCSVWGKA 576
P +YT G+YLV +P+QL T A +L+ G + YI + Q+ FRRT G CS+WGK
Sbjct: 318 PFLYTLQGLYLVYNPIQLSTPHAAGVLILGLVGYYIFRVTNHQKDLFRRTEGNCSIWGKK 377
Query: 575 PSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTVPALFDNFLPYFYVI 396
P+ I +Y + G S L+TSG+WG+ARH +Y ++ + + + ++ LPYFY+I
Sbjct: 378 PTFIECSYQSADGAIHKSKLMTSGFWGVARHMNYTGDLMGSLAYCLACGGNHLLPYFYII 437
Query: 395 FLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
++TILL R RD+ RC +KYGK W+ Y V YR++P I+
Sbjct: 438 YMTILLVHRCIRDEHRCSNKYGKDWERYTAAVSYRLLPNIF 478
>sp|Q5UQI4|DHCR7_MIMIV Probable 7-dehydrocholesterol reductase OS=Acanthamoeba
polyphaga mimivirus GN=DHCR7 PE=3 SV=1
Length = 447
Score = 176 bits (444), Expect = 3e-043
Identities = 88/219 (40%), Positives = 128/219 (58%), Gaps = 7/219 (3%)
Frame = -2
Query: 929 IKQYEINGKVSDSMLVNTILMLVYVTKFFWWEAGYWNTMDIAHDRAGFYICWGCLVWVPS 750
+KQYE G VS+SM++ IL L+Y+ FF+ E Y +T+DIAHD G+ + WG VW+P
Sbjct: 236 MKQYENFGYVSNSMILVIILQLIYIVDFFYNENWYVHTVDIAHDHFGWMLAWGDTVWLPF 295
Query: 749 IYTSPGMYLVNHPVQLGTQLAIYILVAGCLCIYINYDCDRQRQEFRRTNGKCSVWGKAPS 570
YT YL+N+P+ L T + V G + I + Q+ ++R +
Sbjct: 296 GYTLQAGYLMNNPIDLSTGFFNLVFVMGIIGYIIFRTANYQKDKYRSNT-------QGVK 348
Query: 569 KIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTVPALFDNFLPYFYVIFL 390
I TY T G + S L+ SG WG++RH +Y +I + + + F +F+PYFY +++
Sbjct: 349 YIPCTYQTADGLNRASKLIYSGLWGVSRHMNYTGDIILSTAYCLACGFSHFIPYFYCVYM 408
Query: 389 TILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
TILL R RD+ RC KYGKYWK+Y ++V YR IPGIY
Sbjct: 409 TILLVTRCLRDEQRCSRKYGKYWKMYTKRVPYRFIPGIY 447
>sp|Q54PP1|ERG24_DICDI Delta(14)-sterol reductase OS=Dictyostelium discoideum
GN=erg24 PE=3 SV=1
Length = 462
Score = 118 bits (295), Expect = 6e-026
Identities = 74/221 (33%), Positives = 109/221 (49%), Gaps = 12/221 (5%)
Frame = -2
Query: 926 KQYEINGKVSDSMLVNTILMLVYVTKFFWWEAGYWNTMDIAHDRAGFYICWGCLVWVPSI 747
KQ E+ G++S S+++ Y+ +++ E TMDI ++ G+ + +G L WVP
Sbjct: 249 KQLEVYGEISLSVILVCCFHFWYIADYYYHEEAILTTMDIITEKFGYMLVYGDLSWVPFT 308
Query: 746 YTSPGMYLVNHPVQLGTQLAIYILVAGCLCIYINYDCDRQRQEFRRTNGKCSVWGKAPSK 567
Y YL H V G L I I G ++ C FR N + + + P
Sbjct: 309 YCFQCYYLYKHLVN-GAPLHISI---GYAIFVVSLKC-FGFYLFRWVNSQKHDFRRNPEA 363
Query: 566 IV----ATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTVPALFDNFLPYFYV 399
V A + T TK LL SG+WG+ RH +Y +I ++ W +P FD+ PYFY
Sbjct: 364 PVWGKPAEFILTKRGTK---LLCSGFWGICRHLNYTGDIILSWAWCLPCQFDSLAPYFYG 420
Query: 398 IFLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGI 276
I+ T L R RD + C KYG W+ YC++V Y IPG+
Sbjct: 421 IYFTSLDLHRCWRDHNACLVKYGDDWRAYCKRVPYNFIPGL 461
>sp|O08984|LBR_RAT Lamin-B receptor OS=Rattus norvegicus GN=Lbr PE=1 SV=1
Length = 620
Score = 106 bits (262), Expect = 4e-022
Identities = 48/115 (41%), Positives = 68/115 (59%)
Frame = -2
Query: 617 FRRTNGKCSVWGKAPSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTV 438
FR N + + + K P+ + T + LL SGWWG RH +Y+ ++ A W++
Sbjct: 506 FRCANSQKNAFRKNPTDPKLAHLKTIPTSTWKSLLVSGWWGFVRHPNYLGDLIMALAWSL 565
Query: 437 PALFDNFLPYFYVIFLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
P F++ LPYFYVI+ T LL R RD+ +CR KYG W+ YC++V YRI P IY
Sbjct: 566 PCGFNHILPYFYVIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY 620
>sp|Q3U9G9|LBR_MOUSE Lamin-B receptor OS=Mus musculus GN=Lbr PE=1 SV=2
Length = 626
Score = 105 bits (261), Expect = 5e-022
Identities = 47/115 (40%), Positives = 68/115 (59%)
Frame = -2
Query: 617 FRRTNGKCSVWGKAPSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTV 438
FR N + + + K P+ + T + LL SGWWG RH +Y+ ++ A W++
Sbjct: 512 FRCANSQKNAFRKNPTDPKLAHLKTIHTSTGKSLLVSGWWGFVRHPNYLGDLIMALAWSL 571
Query: 437 PALFDNFLPYFYVIFLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
P F++ LPYFY+I+ T LL R RD+ +CR KYG W+ YC++V YRI P IY
Sbjct: 572 PCGFNHLLPYFYIIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY 626
>sp|Q14739|LBR_HUMAN Lamin-B receptor OS=Homo sapiens GN=LBR PE=1 SV=2
Length = 615
Score = 105 bits (260), Expect = 7e-022
Identities = 47/115 (40%), Positives = 68/115 (59%)
Frame = -2
Query: 617 FRRTNGKCSVWGKAPSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTV 438
FR N + + + K PS + T + LL SGWWG RH +Y+ ++ A W++
Sbjct: 501 FRGANSQKNAFRKNPSDPKLAHLKTIHTSTGKNLLVSGWWGFVRHPNYLGDLIMALAWSL 560
Query: 437 PALFDNFLPYFYVIFLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
P F++ LPYFY+I+ T+LL R RD+ C+ KYG W+ YC++V YRI P IY
Sbjct: 561 PCGFNHILPYFYIIYFTMLLVHREARDEYHCKKKYGVAWEKYCQRVPYRIFPYIY 615
>sp|Q09195|ERG24_SCHPO Delta(14)-sterol reductase OS=Schizosaccharomyces pombe
GN=erg24 PE=2 SV=1
Length = 424
Score = 104 bits (259), Expect = 9e-022
Identities = 49/115 (42%), Positives = 70/115 (60%)
Frame = -2
Query: 617 FRRTNGKCSVWGKAPSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTV 438
FR NG+ + + P+ + + + LLTSGWWG+ARH +Y + A+ W +
Sbjct: 310 FRGANGQKNRFRSNPNDPKLKHLKFIQTKRGTKLLTSGWWGMARHINYFGDWIMAWAWCL 369
Query: 437 PALFDNFLPYFYVIFLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
PA F + +PYFYV + +LL R RDD +CR KYG+ W+ YC+ VKYRIIP +Y
Sbjct: 370 PAGFGSPIPYFYVAYFGVLLVHRNARDDHKCRVKYGEDWEKYCKAVKYRIIPYVY 424
>sp|Q5R7H4|LBR_PONAB Lamin-B receptor OS=Pongo abelii GN=LBR PE=2 SV=1
Length = 615
Score = 103 bits (256), Expect = 2e-021
Identities = 47/115 (40%), Positives = 68/115 (59%)
Frame = -2
Query: 617 FRRTNGKCSVWGKAPSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTV 438
FR N + + + K PS + T + LL SGWWG ARH +Y+ ++ A W++
Sbjct: 501 FRGANSQKNAFRKNPSDPKLAHLKTIHTSTGKNLLVSGWWGFARHPNYLGDLIMALAWSL 560
Query: 437 PALFDNFLPYFYVIFLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
F++ LPYFY+I+ T+LL R RD+ C+ KYG W+ YC++V YRI P IY
Sbjct: 561 ACGFNHILPYFYIIYFTMLLVHREARDEYHCKKKYGVAWEKYCQRVPYRIFPYIY 615
>sp|Q71KT5|ERG24_MOUSE Delta(14)-sterol reductase OS=Mus musculus GN=Tm7sf2 PE=2
SV=1
Length = 418
Score = 102 bits (252), Expect = 6e-021
Identities = 46/115 (40%), Positives = 66/115 (57%)
Frame = -2
Query: 617 FRRTNGKCSVWGKAPSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTV 438
FR N + + + K PS T LL SGWWG+ RH +Y+ ++ A W++
Sbjct: 304 FRGANSQKNTFRKNPSDPSVAGLETIPTATGRQLLVSGWWGMVRHPNYLGDLIMALAWSL 363
Query: 437 PALFDNFLPYFYVIFLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
P + LPYFYV++ T LL R RD+ +C KYG+ W+ YC++V YRIIP +Y
Sbjct: 364 PCGLSHLLPYFYVLYFTALLVHREARDEQQCLQKYGRAWQEYCKRVPYRIIPYVY 418
>sp|Q8WMV1|ERG24_BOVIN Delta(14)-sterol reductase OS=Bos taurus GN=TM7SF2 PE=1
SV=1
Length = 418
Score = 97 bits (241), Expect = 1e-019
Identities = 45/115 (39%), Positives = 63/115 (54%)
Frame = -2
Query: 617 FRRTNGKCSVWGKAPSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTV 438
FR N + + + K PS T LL SGWWG+ RH +Y+ ++ A W++
Sbjct: 304 FRGANSQKNTFRKNPSDPRVADLETISTATGRRLLVSGWWGMVRHPNYLGDLIMALAWSL 363
Query: 437 PALFDNFLPYFYVIFLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
P + LPYFY ++ T LL R RD+ +CR KYG W YC +V YRI+P +Y
Sbjct: 364 PCGVFHLLPYFYFLYFTALLVHREDRDERQCRQKYGLAWHEYCRRVPYRIVPYVY 418
>sp|P78575|ERG24_ASCIM Delta(14)-sterol reductase OS=Ascobolus immersus GN=ERG3
PE=3 SV=1
Length = 430
Score = 97 bits (240), Expect = 1e-019
Identities = 48/115 (41%), Positives = 67/115 (58%)
Frame = -2
Query: 617 FRRTNGKCSVWGKAPSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTV 438
FR N + + + P+ ++ S LL SGWWG+ARH +Y + A+ + +
Sbjct: 316 FRGANNQKNAFRTNPADPAVSHLKFMTTKSGSKLLISGWWGVARHVNYFGDWIMAWSYCL 375
Query: 437 PALFDNFLPYFYVIFLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
F+ L YFYVI+ ILL R +RD+ +CR KYGK W YC+ VK+RIIPGIY
Sbjct: 376 TTGFNTPLTYFYVIYFGILLLHRDRRDEAKCREKYGKDWDRYCKVVKWRIIPGIY 430
>sp|O76062|ERG24_HUMAN Delta(14)-sterol reductase OS=Homo sapiens GN=TM7SF2 PE=2
SV=3
Length = 418
Score = 97 bits (240), Expect = 1e-019
Identities = 45/115 (39%), Positives = 64/115 (55%)
Frame = -2
Query: 617 FRRTNGKCSVWGKAPSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTV 438
FR N + + + K PS T LL SGWWG+ RH +Y+ ++ A W++
Sbjct: 304 FRGANSQKNTFRKNPSDPRVAGLETISTATGRKLLVSGWWGMVRHPNYLGDLIMALAWSL 363
Query: 437 PALFDNFLPYFYVIFLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKYRIIPGIY 273
P + LPYFY+++ T LL R RD+ +C KYG W+ YC +V YRI+P IY
Sbjct: 364 PCGVSHLLPYFYLLYFTALLVHREARDERQCLQKYGLAWQEYCRRVPYRIMPYIY 418
>sp|P23913|LBR_CHICK Lamin-B receptor OS=Gallus gallus GN=LBR PE=2 SV=1
Length = 637
Score = 90 bits (221), Expect = 2e-017
Identities = 40/108 (37%), Positives = 60/108 (55%)
Frame = -2
Query: 617 FRRTNGKCSVWGKAPSKIVATYTTTAGETKTSLLLTSGWWGLARHFHYVPEISSAFFWTV 438
FR N + + + + P+ +Y LL +GWWG RH +Y+ +I A W++
Sbjct: 494 FRSANSQKNNFRRNPADPKLSYLKVIPTATGKGLLVTGWWGFVRHPNYLGDIIMALAWSL 553
Query: 437 PALFDNFLPYFYVIFLTILLFDRAKRDDDRCRSKYGKYWKLYCEKVKY 294
P F++ LPYFYVI+ LL R RD+ C+ KYG W+ YC++V Y
Sbjct: 554 PCGFNHILPYFYVIYFICLLVHREARDEHHCKKKYGLAWERYCQRVPY 601
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,583,480,646
Number of Sequences: 518415
Number of Extensions: 13583480646
Number of Successful Extensions: 94382982
Number of sequences better than 0.0: 0
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