BLASTX 7.6.2
Query= UN03571 /QuerySize=1007
(1006 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O82197|VP321_ARATH Vacuolar protein sorting-associated protei... 335 3e-091
sp|Q9SZE4|VP322_ARATH Vacuolar protein sorting-associated protei... 330 1e-089
sp|Q6IQ73|CHM4C_DANRE Charged multivesicular body protein 4c OS=... 138 1e-031
sp|Q7ZVC4|CHM4B_DANRE Charged multivesicular body protein 4b OS=... 135 5e-031
sp|Q5XGW6|CHM4B_XENLA Charged multivesicular body protein 4b OS=... 132 6e-030
sp|Q6GL11|CHM4B_XENTR Charged multivesicular body protein 4b OS=... 131 1e-029
sp|Q86H98|CHMP4_DICDI Charged multivesicular body protein 4 OS=D... 131 1e-029
sp|Q6GNN8|CHM4C_XENLA Charged multivesicular body protein 4c OS=... 127 1e-028
sp|Q9H444|CHM4B_HUMAN Charged multivesicular body protein 4b OS=... 125 5e-028
sp|Q9D8B3|CHM4B_MOUSE Charged multivesicular body protein 4b OS=... 125 5e-028
sp|Q5ZHP5|CHM4B_CHICK Charged multivesicular body protein 4b OS=... 125 7e-028
sp|Q9P7F7|SNF7_SCHPO Vacuolar-sorting protein snf7 OS=Schizosacc... 121 1e-026
sp|Q9BY43|CHM4A_HUMAN Charged multivesicular body protein 4a OS=... 121 1e-026
sp|A2VDY3|CHM4A_BOVIN Charged multivesicular body protein 4a OS=... 114 1e-024
sp|Q6FW96|SNF7_CANGA Vacuolar-sorting protein SNF7 OS=Candida gl... 114 1e-024
sp|Q96CF2|CHM4C_HUMAN Charged multivesicular body protein 4c OS=... 111 8e-024
sp|Q5ABD0|SNF7_CANAL Vacuolar-sorting protein SNF7 OS=Candida al... 111 1e-023
sp|Q6CJL0|SNF7_KLULA Vacuolar-sorting protein SNF7 OS=Kluyveromy... 106 3e-022
sp|Q569C1|CHM4C_RAT Charged multivesicular body protein 4c OS=Ra... 104 2e-021
sp|P39929|SNF7_YEAST Vacuolar-sorting protein SNF7 OS=Saccharomy... 104 2e-021
>sp|O82197|VP321_ARATH Vacuolar protein sorting-associated protein 32 homolog 1
OS=Arabidopsis thaliana GN=VPS32.1 PE=2 SV=1
Length = 213
Score = 335 bits (859), Expect = 3e-091
Identities = 180/210 (85%), Positives = 192/210 (91%), Gaps = 3/210 (1%)
Frame = +2
Query: 164 RLFGKPKEETNTLHTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKRAAIQCL 343
RLFGKPK+ET+TL TL KLNETLEMLEKKE+VLLKKA GEVE+AKEFS+ KNKRAAIQCL
Sbjct: 5 RLFGKPKQETSTLQTLDKLNETLEMLEKKENVLLKKATGEVEKAKEFSRAKNKRAAIQCL 64
Query: 344 KRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKATNIDDVD 523
KRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGA+AMKAMQKATNIDDVD
Sbjct: 65 KRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGASAMKAMQKATNIDDVD 124
Query: 524 KTMDEINEQTDNMKQIQDALSAPFGSAADFDEDELEAELDELEGLELEDQLLQPAR-PLP 700
KTMDEINEQT+NMKQIQ+ALSAPFG A DFDEDELEAELDELEG ELE+QLLQP +P
Sbjct: 125 KTMDEINEQTENMKQIQEALSAPFG-ANDFDEDELEAELDELEGAELEEQLLQPVPIHVP 183
Query: 701 EGKLPARPLPQKKQTADEEDELAALQAEMA 790
+G PAR QK+ TA EEDELAALQAEMA
Sbjct: 184 QGNKPARAPAQKQPTA-EEDELAALQAEMA 212
>sp|Q9SZE4|VP322_ARATH Vacuolar protein sorting-associated protein 32 homolog 2
OS=Arabidopsis thaliana GN=VPS32.2 PE=2 SV=1
Length = 219
Score = 330 bits (845), Expect = 1e-089
Identities = 174/221 (78%), Positives = 189/221 (85%), Gaps = 10/221 (4%)
Frame = +2
Query: 155 MFTRLFGKPKEETNTLHTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKRAAI 334
M RLFGKPK+E N L TL KLNETLEMLEKKE VLLKKA EVE+AKE+S+ KNKRAAI
Sbjct: 1 MMNRLFGKPKQEANALQTLDKLNETLEMLEKKEKVLLKKAGAEVEKAKEYSRAKNKRAAI 60
Query: 335 QCLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKATNID 514
QCLKRKRLYE QVEQLGNFQLRIHDQMIMLEGAKATTETVDALR+GA+AMKAMQKATNID
Sbjct: 61 QCLKRKRLYEGQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNID 120
Query: 515 DVDKTMDEINEQTDNMKQIQDALSAPFGSAADFDEDELEAELDELEGLELEDQLLQPAR- 691
DVDKTMDEINEQT+NMKQIQ+AL+ P G+AADFDEDEL AELDELE ELE QLLQPA
Sbjct: 121 DVDKTMDEINEQTENMKQIQEALATPMGAAADFDEDELAAELDELESEELESQLLQPATT 180
Query: 692 -------PLPEGKLPARPLPQKKQTADEEDELAALQAEMAL 793
P+P G+ PARP+PQK+ EE+ELAALQAEMAL
Sbjct: 181 APPLPSVPVPAGRQPARPVPQKRTA--EEEELAALQAEMAL 219
>sp|Q6IQ73|CHM4C_DANRE Charged multivesicular body protein 4c OS=Danio rerio
GN=chmp4c PE=2 SV=1
Length = 224
Score = 138 bits (345), Expect = 1e-031
Identities = 90/220 (40%), Positives = 125/220 (56%), Gaps = 12/220 (5%)
Frame = +2
Query: 155 MFTRLF---GKPKEETNTLHTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKR 325
+F +LF GK + + KL ET EML KK+ L KK E+ AK+ + KNKR
Sbjct: 3 VFGKLFGGGGKGGKGPTPQEAIQKLRETEEMLAKKQDFLEKKIDAELLIAKK-NGTKNKR 61
Query: 326 AAIQCLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKAT 505
AA+Q LKRK+ YE+Q+ Q+ I Q LE A TE + + A AMK +
Sbjct: 62 AALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKTAHENM 121
Query: 506 NIDDVDKTMDEINEQTDNMKQIQDALSAPFGSAADFDEDELEAELDELEGLELEDQLLQP 685
+ID VD M +I EQ + ++I DA+S P G +FDEDEL AEL+ELE EL+ LLQ
Sbjct: 122 DIDKVDDLMQDITEQQELAQEISDAISRPVGFGEEFDEDELMAELEELEQEELDKDLLQI 181
Query: 686 ARP--LPEGKLPARPLP------QKKQTADEEDELAALQA 781
+ P +P +P+ PLP QKK+ ++ED++ L+A
Sbjct: 182 SGPEDVPLPNVPSNPLPKKTAVAQKKRQEEDEDDMEELKA 221
>sp|Q7ZVC4|CHM4B_DANRE Charged multivesicular body protein 4b OS=Danio rerio
GN=chmp4b PE=2 SV=1
Length = 220
Score = 135 bits (339), Expect = 5e-031
Identities = 87/217 (40%), Positives = 124/217 (57%), Gaps = 11/217 (5%)
Frame = +2
Query: 155 MFTRLF---GKPKEETNTLHTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKR 325
+F ++F GK + + + +L ET EML KK+ L KK E+ AK+ + KNKR
Sbjct: 3 LFGKMFGSGGKGGKSASPQEAIQRLRETEEMLTKKQEFLEKKIEQELVTAKK-NGTKNKR 61
Query: 326 AAIQCLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKAT 505
AA+Q LKRK+ YE+Q+ Q+ I Q LE A TE + + A AMKA
Sbjct: 62 AALQALKRKKRYEKQLAQIDGTLSTIEFQREALENAHTNTEVIKNMGYAAKAMKAAHDNM 121
Query: 506 NIDDVDKTMDEINEQTDNMKQIQDALSAPFGSAADFDEDELEAELDELEGLELEDQLLQ- 682
+ID VD+ M +I EQ + ++I DA+S P G +FDEDEL AEL+ELE EL+ LL+
Sbjct: 122 DIDKVDELMQDIIEQQELAQEISDAISKPVGFGEEFDEDELLAELEELEQEELDKNLLEI 181
Query: 683 ----PARPLPEGKLPARPLPQKKQTADEEDELAALQA 781
P +P LP+R P KK+ ++ED++ L+A
Sbjct: 182 GDNVPLPNVPSTSLPSR--PAKKKEEEDEDDMKDLEA 216
>sp|Q5XGW6|CHM4B_XENLA Charged multivesicular body protein 4b OS=Xenopus laevis
GN=chmp4b PE=2 SV=1
Length = 222
Score = 132 bits (330), Expect = 6e-030
Identities = 83/203 (40%), Positives = 115/203 (56%), Gaps = 9/203 (4%)
Frame = +2
Query: 173 GKPKEETNTLHTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKRAAIQCLKRK 352
GK + + + KL +T EML KK+ L KK E+ AK+ KNKRAA+Q LKRK
Sbjct: 12 GKGAKGPSPQEAIQKLRDTEEMLAKKQEFLEKKIEQELVTAKKHG-TKNKRAALQALKRK 70
Query: 353 RLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKATNIDDVDKTM 532
+ YE+Q+ Q+ I Q LE A TE + + A AMKA +I+ VD+ M
Sbjct: 71 KRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIEKVDELM 130
Query: 533 DEINEQTDNMKQIQDALSAPFGSAADFDEDELEAELDELEGLELEDQLLQ-------PAR 691
+I +Q + ++I DA+S P G DFDEDEL AEL+ELE EL+ LL+ P
Sbjct: 131 QDIADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEELDKNLLEVQGPETVPLP 190
Query: 692 PLPEGKLPARPLPQKKQTADEED 760
+P LPA+P+ +KKQ D++D
Sbjct: 191 NVPAASLPAKPV-KKKQEEDDDD 212
>sp|Q6GL11|CHM4B_XENTR Charged multivesicular body protein 4b OS=Xenopus
tropicalis GN=chmp4b PE=2 SV=1
Length = 222
Score = 131 bits (328), Expect = 1e-029
Identities = 83/203 (40%), Positives = 115/203 (56%), Gaps = 9/203 (4%)
Frame = +2
Query: 173 GKPKEETNTLHTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKRAAIQCLKRK 352
GK + + + KL +T EML KK+ L KK E+ AK+ KNKRAA+Q LKRK
Sbjct: 12 GKGAKGPSPQEAIQKLRDTEEMLTKKQEFLEKKIEQELVTAKKHG-TKNKRAALQALKRK 70
Query: 353 RLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKATNIDDVDKTM 532
+ YE+Q+ Q+ I Q LE A TE + + A AMKA +I+ VD+ M
Sbjct: 71 KRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIEKVDELM 130
Query: 533 DEINEQTDNMKQIQDALSAPFGSAADFDEDELEAELDELEGLELEDQLLQ-------PAR 691
+I +Q + ++I DA+S P G DFDEDEL AEL+ELE EL+ LL+ P
Sbjct: 131 QDIADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEELDKNLLEVQGPETVPLP 190
Query: 692 PLPEGKLPARPLPQKKQTADEED 760
+P LPA+P+ +KKQ D++D
Sbjct: 191 NVPAAVLPAKPV-KKKQEEDDDD 212
>sp|Q86H98|CHMP4_DICDI Charged multivesicular body protein 4 OS=Dictyostelium
discoideum GN=chmp4 PE=3 SV=1
Length = 215
Score = 131 bits (328), Expect = 1e-029
Identities = 79/215 (36%), Positives = 126/215 (58%), Gaps = 6/215 (2%)
Frame = +2
Query: 164 RLFGKPKEETNTLHTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKRAAIQCL 343
+LFGKPK + +T T+GKL TL+MLEK+++ L K E E+AK K KR A+ CL
Sbjct: 2 KLFGKPKPKQDTQETIGKLRLTLDMLEKRQTFLQDKLEKEQEKAKVLVSQKRKREALLCL 61
Query: 344 KRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKATNIDDVD 523
K++ ++ +V +L ++ Q+ LE AK E ++++R GA +++ + ID VD
Sbjct: 62 KKRNNFQNEVTKLQGSYDTLNQQIFALENAKMNMEIMNSMRDGARSLRELHGHLTIDKVD 121
Query: 524 KTMDEINEQTDNMKQIQDALSAPFGSAADFDEDELEAELDELEGLELEDQLLQ---PARP 694
++EI EQ + ++I +A+S P G+ + DE+EL EL E E EL+ QLL P+R
Sbjct: 122 DVIEEIQEQMEIHEEISNAISQPLGNQVE-DEEELLRELAEYEQEELDAQLLNIKAPSRE 180
Query: 695 LPEGKLPARPLPQK--KQTADEEDELAALQAEMAL 793
LP+ P K + + EE+E+ AL+ +A+
Sbjct: 181 LPQEIQVNFPTISKTVPKLSKEEEEIRALEESLAM 215
>sp|Q6GNN8|CHM4C_XENLA Charged multivesicular body protein 4c OS=Xenopus laevis
GN=chmp4c PE=2 SV=1
Length = 227
Score = 127 bits (318), Expect = 1e-028
Identities = 77/201 (38%), Positives = 112/201 (55%), Gaps = 7/201 (3%)
Frame = +2
Query: 176 KPKEETNTLHTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKRAAIQCLKRKR 355
K ++ + L KL ET EML KK+ L KK E+ AK+ KNKRAA+Q LK+K+
Sbjct: 19 KNRKGPSAQEALFKLRETEEMLTKKQEYLEKKIELELATAKKHG-TKNKRAALQALKKKK 77
Query: 356 LYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKATNIDDVDKTMD 535
E+Q+ Q+ I Q LE + TE + + A AMKA + +++ +D M
Sbjct: 78 RLEKQLAQIDGTLSTIEFQREALENSHTNTEVLKNMGYAAKAMKAAHENMDLEKIDDLMQ 137
Query: 536 EINEQTDNMKQIQDALSAPFGSAADFDEDELEAELDELEGLELEDQLLQ------PARPL 697
+I+EQ D ++I DA+S P G +FDEDEL EL+ELE +L Q+ P+ L
Sbjct: 138 DIHEQQDVAQEISDAISRPVGFGDEFDEDELLEELEELEQEDLNSQMANVNLPSVPSSKL 197
Query: 698 PEGKLPARPLPQKKQTADEED 760
P KLP+RP +K+ D++D
Sbjct: 198 PSTKLPSRPASSRKKVEDDDD 218
>sp|Q9H444|CHM4B_HUMAN Charged multivesicular body protein 4b OS=Homo sapiens
GN=CHMP4B PE=1 SV=1
Length = 224
Score = 125 bits (313), Expect = 5e-028
Identities = 83/217 (38%), Positives = 120/217 (55%), Gaps = 10/217 (4%)
Frame = +2
Query: 155 MFTRLFG-----KPKEETNTLHTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKN 319
+F +LFG K + +L +T EML KK+ L KK E+ AK+ KN
Sbjct: 3 VFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHG-TKN 61
Query: 320 KRAAIQCLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQK 499
KRAA+Q LKRK+ YE+Q+ Q+ I Q LE A TE + + A AMKA
Sbjct: 62 KRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHD 121
Query: 500 ATNIDDVDKTMDEINEQTDNMKQIQDALSAPFGSAADFDEDELEAELDELEGLELEDQLL 679
+ID VD+ M +I +Q + ++I A+S P G +FDEDEL AEL+ELE EL+ LL
Sbjct: 122 NMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLL 181
Query: 680 QPARP--LPEGKLPARPLPQK--KQTADEEDELAALQ 778
+ + P +P +P+ LP K K+ +E+D++ L+
Sbjct: 182 EISGPETVPLPNVPSIALPSKPAKKKEEEDDDMKELE 218
>sp|Q9D8B3|CHM4B_MOUSE Charged multivesicular body protein 4b OS=Mus musculus
GN=Chmp4b PE=2 SV=2
Length = 224
Score = 125 bits (313), Expect = 5e-028
Identities = 82/216 (37%), Positives = 117/216 (54%), Gaps = 13/216 (6%)
Frame = +2
Query: 155 MFTRLFG-----KPKEETNTLHTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKN 319
+F +LFG K + +L +T EML KK+ L KK E+ AK+ KN
Sbjct: 3 VFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHG-TKN 61
Query: 320 KRAAIQCLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQK 499
KRAA+Q LKRK+ YE+Q+ Q+ I Q LE A TE + + A AMKA
Sbjct: 62 KRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHD 121
Query: 500 ATNIDDVDKTMDEINEQTDNMKQIQDALSAPFGSAADFDEDELEAELDELEGLELEDQLL 679
+ID VD+ M +I +Q + ++I A+S P G +FDEDEL AEL+ELE EL+ LL
Sbjct: 122 NMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLL 181
Query: 680 QPARP-------LPEGKLPARPLPQKKQTADEEDEL 766
+ + P +P LP++P +K++ D+ EL
Sbjct: 182 EISGPETVPLPNVPSVALPSKPAKKKEEEDDDMKEL 217
>sp|Q5ZHP5|CHM4B_CHICK Charged multivesicular body protein 4b OS=Gallus gallus
GN=CHMP4B PE=2 SV=1
Length = 227
Score = 125 bits (312), Expect = 7e-028
Identities = 78/196 (39%), Positives = 112/196 (57%), Gaps = 10/196 (5%)
Frame = +2
Query: 215 KLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKRAAIQCLKRKRLYEQQVEQLGNFQ 394
+L +T EML KK+ L KK E+ A++ KNKRAA+Q LKRK+ YE+Q+ Q+
Sbjct: 30 RLRDTEEMLSKKQEFLEKKIEQELAAARKHG-TKNKRAALQALKRKKRYEKQLAQIDGTL 88
Query: 395 LRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKATNIDDVDKTMDEINEQTDNMKQIQ 574
I Q LE A TE + + A AMKA +ID VD+ M +I EQ + +I
Sbjct: 89 STIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIDKVDELMQDIAEQQELADEIS 148
Query: 575 DALSAPFGSAADFDEDELEAELDELEGLELEDQLLQPARP-------LPEGKLPARPLPQ 733
A+S P G +FDEDEL AEL+ELE EL+ LL+ + P +P +P++ P
Sbjct: 149 TAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPSISIPSK--PA 206
Query: 734 KKQTADEEDELAALQA 781
KK+ +E+D++ L+A
Sbjct: 207 KKKEEEEDDDMKELEA 222
>sp|Q9P7F7|SNF7_SCHPO Vacuolar-sorting protein snf7 OS=Schizosaccharomyces pombe
GN=snf7 PE=2 SV=1
Length = 222
Score = 121 bits (302), Expect = 1e-026
Identities = 64/179 (35%), Positives = 107/179 (59%), Gaps = 1/179 (0%)
Frame = +2
Query: 158 FTRLFGKPKEETNTLHTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKRAAIQ 337
F R FG + + T T+ + E L + +KKE VL ++ A + E A++ + NKR A+
Sbjct: 4 FLRWFGGNRSKDTTKDTIVRFQEMLALYDKKEEVLERQIAEQTEIARK-NATTNKRLALT 62
Query: 338 CLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKATNIDD 517
LKRK+++E ++ ++ + I Q+ ++ A ET+ A+R GA AMK++Q+ + D
Sbjct: 63 ALKRKKMHENELVKIEGSRNNIEQQLFSIQNANLNFETLQAMRQGAEAMKSIQRGMDADK 122
Query: 518 VDKTMDEINEQTDNMKQIQDALSAPFGSAADFDEDELEAELDELEGLELEDQLLQPARP 694
VD+ MD+I +Q ++I +S P G A+ DEDEL ELDEL+ +EL+ ++L +P
Sbjct: 123 VDQIMDKIRDQQTISEEISTMISTPVGLNAEIDEDELANELDELQQMELDSKMLGAEKP 181
>sp|Q9BY43|CHM4A_HUMAN Charged multivesicular body protein 4a OS=Homo sapiens
GN=CHMP4A PE=1 SV=3
Length = 222
Score = 121 bits (301), Expect = 1e-026
Identities = 83/219 (37%), Positives = 117/219 (53%), Gaps = 17/219 (7%)
Frame = +2
Query: 164 RLFGKPKEETNTL--HTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKRAAIQ 337
RLFGK K+E + KL ET ++L KK+ L +K E++ AK++ KNKRAA+Q
Sbjct: 6 RLFGKGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYG-TKNKRAALQ 64
Query: 338 CLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKATNIDD 517
L+RK+ +EQQ+ Q + Q +E A E + + A +MK + +ID
Sbjct: 65 ALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDK 124
Query: 518 VDKTMDEINEQTDNMKQIQDALSAPFGSAADFDEDELEAELDELEGLELEDQLL------ 679
VD+ M +I EQ + +QI DA+S P G D DEDEL EL+ELE EL +LL
Sbjct: 125 VDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKE 184
Query: 680 -QPARPL---PEGKLPARPLPQKKQTADEEDELAALQAE 784
+P+ L P LPA P P+ DE++E AE
Sbjct: 185 EEPSVKLPSVPSTHLPAGPAPK----VDEDEEALKQLAE 219
>sp|A2VDY3|CHM4A_BOVIN Charged multivesicular body protein 4a OS=Bos taurus
GN=CHMP4A PE=2 SV=1
Length = 222
Score = 114 bits (284), Expect = 1e-024
Identities = 79/214 (36%), Positives = 111/214 (51%), Gaps = 13/214 (6%)
Frame = +2
Query: 164 RLFGKPKEETNTL--HTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKRAAIQ 337
RLFG+ K+E + KL ET ++L KK+ L +K E++ AK+ KNKRAA+Q
Sbjct: 6 RLFGRGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIEQELQAAKKHG-TKNKRAALQ 64
Query: 338 CLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKATNIDD 517
L+RK+ EQQ+ Q + Q +E A E + + A +K + +ID
Sbjct: 65 ALRRKKRLEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQGLKKAYQDMDIDK 124
Query: 518 VDKTMDEINEQTDNMKQIQDALSAPFGSAADFDEDELEAELDELEGLELEDQLL------ 679
VD+ M +I EQ + +QI DA+S P G D DEDEL EL+ELE EL +LL
Sbjct: 125 VDELMADITEQQEVAQQISDAISRPVGFGDDVDEDELLEELEELEQEELARELLHVGDEE 184
Query: 680 -QPARPLPEG---KLPARPLPQKKQTADEEDELA 769
+P LP LPA P P+ + E +LA
Sbjct: 185 EEPPVALPSAPSTHLPAEPAPKADEDEAELKQLA 218
>sp|Q6FW96|SNF7_CANGA Vacuolar-sorting protein SNF7 OS=Candida glabrata GN=SNF7
PE=3 SV=1
Length = 228
Score = 114 bits (284), Expect = 1e-024
Identities = 74/207 (35%), Positives = 113/207 (54%), Gaps = 15/207 (7%)
Frame = +2
Query: 215 KLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKRAAIQCLKRKRLYEQQVEQLGNFQ 394
+L E + +L KK++ L + + A++F NK A LK+K++YE Q+ +L +
Sbjct: 23 ELREHINLLSKKQAHLQGQITAQENEARKFLTRGNKTMAKNALKKKKVYEGQLVKLESQM 82
Query: 395 LRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKATNIDDVDKTMDEINEQTDNMKQIQ 574
+ Q+ +E A ET+ A++ GA AMK++ +ID VD+TMDEI EQ + ++I
Sbjct: 83 DSLEQQLFSIESANLNLETMRAMKQGAKAMKSIHSGLDIDRVDETMDEIREQVELGEEIS 142
Query: 575 DALSAP-FGSAADFDEDELEAELDELEGLELEDQLLQPARPLPEGK-------LPARPLP 730
DA+S P + A + DEDEL+ ELD L E E Q+ + LPE K +P +
Sbjct: 143 DAISRPLYTGANEIDEDELDEELDML-AQETEPQVATKEQALPESKQALSMPNIPNTKID 201
Query: 731 QKKQTADEEDE------LAALQAEMAL 793
+ K +EE+E L LQAEM L
Sbjct: 202 ESKTKIEEEEEDEDERALRELQAEMGL 228
>sp|Q96CF2|CHM4C_HUMAN Charged multivesicular body protein 4c OS=Homo sapiens
GN=CHMP4C PE=1 SV=1
Length = 233
Score = 111 bits (277), Expect = 8e-024
Identities = 74/206 (35%), Positives = 109/206 (52%), Gaps = 4/206 (1%)
Frame = +2
Query: 176 KPKEETNTLHTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKRAAIQCLKRKR 355
K + + L +L ET EML KK+ L + E+ AK+ +NKRAA+Q LKRK+
Sbjct: 15 KSRAAPSPQEALVRLRETEEMLGKKQEYLENRIQREIALAKKHG-TQNKRAALQALKRKK 73
Query: 356 LYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKATNIDDVDKTMD 535
+E+Q+ Q+ I Q LE + TE + + A AMK++ + +++ +D M
Sbjct: 74 RFEKQLTQIDGTLSTIEFQREALENSHTNTEVLRNMGFAAKAMKSVHENMDLNKIDDLMQ 133
Query: 536 EINEQTDNMKQIQDALSAPFGSAADFDEDELEAELDELEGLELEDQLLQPARP-LPEGKL 712
EI EQ D ++I +A S G DFDEDEL AEL+ELE EL ++ P +P L
Sbjct: 134 EITEQQDIAQEISEAFSQRVGFGDDFDEDELMAELEELEQEELNKKMTNIRLPNVPSSSL 193
Query: 713 PARP--LPQKKQTADEEDELAALQAE 784
PA+P P TA ++ +AE
Sbjct: 194 PAQPNRKPGMSSTARRSRAASSQRAE 219
>sp|Q5ABD0|SNF7_CANAL Vacuolar-sorting protein SNF7 OS=Candida albicans GN=SNF7
PE=3 SV=1
Length = 226
Score = 111 bits (275), Expect = 1e-023
Identities = 80/227 (35%), Positives = 119/227 (52%), Gaps = 15/227 (6%)
Frame = +2
Query: 155 MFTRLFGKPKEETNTL--HTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKRA 328
M+ FG ++ L + +L E ++ L KK++ L ++ + + A+++ K
Sbjct: 1 MWGYFFGGNSQQKKDLPKKAIVELREHIQTLNKKKNHLQQQMDDQDQLARKYVSSKQTTL 60
Query: 329 AIQCLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKATN 508
A LKRK+ YE + ++ N + Q+I +EGA ET+ A++ GA AMK + +
Sbjct: 61 AKSALKRKKGYESNLLKVENQIETLETQLISIEGANLNLETMKAMKQGAKAMKQIHGEYD 120
Query: 509 IDDVDKTMDEINEQTDNMKQIQDALSAPFGSAADFDEDELEAELDELEGLELEDQL---- 676
+D V+ TMDEI EQ + +I +A+S P G+ DEDEL+ EL ELE E +
Sbjct: 121 VDKVEDTMDEIREQVELADEISEAISRPVGNEF-VDEDELDEELKELEAEAKEQEQEHRV 179
Query: 677 -LQPARPLP---EGKLPARPLPQKKQTADEEDE----LAALQAEMAL 793
Q A+P P E +LP P KK EEDE L ALQAEM L
Sbjct: 180 PAQKAKPQPVSREEELPQFPSVNKKAPVVEEDEDEEALKALQAEMGL 226
>sp|Q6CJL0|SNF7_KLULA Vacuolar-sorting protein SNF7 OS=Kluyveromyces lactis
GN=SNF7 PE=3 SV=1
Length = 232
Score = 106 bits (263), Expect = 3e-022
Identities = 68/211 (32%), Positives = 114/211 (54%), Gaps = 2/211 (0%)
Frame = +2
Query: 155 MFTRLFGKPKEETN-TLHTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKRAA 331
M+ FG K++ + L E +++L KK++ L + + + AK+ + NK A
Sbjct: 1 MWGYFFGTSKQQKELPKKAIVDLREHIQLLNKKQAHLQTQIDQQQQLAKKSLQSGNKNNA 60
Query: 332 IQCLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKATNI 511
LK+K+LYE Q+++L + + Q+ +E A ET+ A++ GA+AMK + K ++
Sbjct: 61 KTYLKKKKLYESQLDKLQSQIDSLDQQLYSIENANLNLETLKAMKQGASAMKNIHKGLDL 120
Query: 512 DDVDKTMDEINEQTDNMKQIQDALSAPFGSAADFDEDELEAELDELEGLELEDQLLQPAR 691
D VD TMDEI EQ + ++I +A+S P + DEDEL+ EL+ LE L+ + + P
Sbjct: 121 DKVDDTMDEIREQVELNQEISEAISKPLILQDELDEDELDQELELLESENLQKEHIAPV- 179
Query: 692 PLPEGKLPARPLPQKKQTADEEDELAALQAE 784
P + + P+ LP EL + QA+
Sbjct: 180 PQQQIQQPSIDLPSVPDVKLSTPELNSAQAD 210
>sp|Q569C1|CHM4C_RAT Charged multivesicular body protein 4c OS=Rattus norvegicus
GN=Chmp4c PE=2 SV=1
Length = 232
Score = 104 bits (257), Expect = 2e-021
Identities = 65/173 (37%), Positives = 96/173 (55%), Gaps = 2/173 (1%)
Frame = +2
Query: 209 LGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNKRAAIQCLKRKRLYEQQVEQLGN 388
L +L E EM+ KK+ L + E+ AK+ +NKRAA+Q LKRK+ +E+Q+ Q+
Sbjct: 26 LARLREIEEMMAKKQEYLENRIQRELALAKKHGS-QNKRAALQALKRKKRFEKQLTQIDG 84
Query: 389 FQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKATNIDDVDKTMDEINEQTDNMKQ 568
I Q LE + TE + + A AMKA+ + +++ +D M +I EQ D ++
Sbjct: 85 TLSTIEFQREALENSHTNTEVLRNMGFAAKAMKAVHENMDLNKIDDLMQDITEQQDIAQE 144
Query: 569 IQDALSAPFGSAADFDEDELEAELDELEGLELEDQLLQPARP-LPEGKLPARP 724
I +A S A FDEDEL AEL+ELE EL ++ P +P LPA+P
Sbjct: 145 ISEAFSQRVQFADGFDEDELLAELEELEQEELNKKMTSMELPNVPSSSLPAQP 197
>sp|P39929|SNF7_YEAST Vacuolar-sorting protein SNF7 OS=Saccharomyces cerevisiae
GN=SNF7 PE=1 SV=1
Length = 240
Score = 104 bits (257), Expect = 2e-021
Identities = 79/240 (32%), Positives = 116/240 (48%), Gaps = 27/240 (11%)
Frame = +2
Query: 155 MFTRLFG----KPKEETNTLHTLGKLNETLEMLEKKESVLLKKAAGEVERAKEFSKVKNK 322
M++ LFG K + + + +L E + +L KK+S L + + A+ F NK
Sbjct: 1 MWSSLFGWTSSNAKNKESPTKAIVRLREHINLLSKKQSHLRTQITNQENEARIFLTKGNK 60
Query: 323 RAAIQCLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGAAAMKAMQKA 502
A LK+K+ EQ + ++ + Q+ +E A ET+ A++ GA AMK +
Sbjct: 61 VMAKNALKKKKTIEQLLSKVEGTMESMEQQLFSIESANLNLETMRAMQEGAKAMKTIHSG 120
Query: 503 TNIDDVDKTMDEINEQTDNMKQIQDALSAPFGSAA-DFDEDELEAELDEL--EGLELEDQ 673
+ID VD+TMDEI EQ + +I DA+S P + A + DEDEL+ ELD L E E
Sbjct: 121 LDIDKVDETMDEIREQVELGDEISDAISRPLITGANEVDEDELDEELDMLAQENANQETS 180
Query: 674 LL----QPARPLPEGKLPARPLPQKK------------QTADEEDE----LAALQAEMAL 793
+ A P+ E K+ +P K + DEEDE L LQAEM L
Sbjct: 181 KIVNNNVNAAPISENKVSLPSVPSNKIKQSENSVKDGEEEEDEEDEDEKALRELQAEMGL 240
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,545,185,555
Number of Sequences: 518415
Number of Extensions: 16545185555
Number of Successful Extensions: 102511304
Number of sequences better than 0.0: 0
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