BLASTX 7.6.2
Query= UN04352 /QuerySize=1228
(1227 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54PK9|PDPKB_DICDI 3-phosphoinositide-dependent protein kinas... 244 1e-063
sp|P34102|PK3_DICDI Protein kinase 3 OS=Dictyostelium discoideum... 226 3e-058
sp|Q39030|KPK19_ARATH Serine/threonine-protein kinase AtPK19 OS=... 222 6e-057
sp|O15530|PDPK1_HUMAN 3-phosphoinositide-dependent protein kinas... 158 1e-037
sp|Q9Z2A0|PDPK1_MOUSE 3-phosphoinositide-dependent protein kinas... 158 1e-037
sp|O55173|PDPK1_RAT 3-phosphoinositide-dependent protein kinase ... 158 1e-037
sp|Q6A1A2|PDPK2_HUMAN Putative 3-phosphoinositide-dependent prot... 155 7e-037
sp|Q54TW2|PDPKA_DICDI Probable serine/threonine-protein kinase p... 154 1e-036
sp|P42818|KPK1_ARATH Serine/threonine-protein kinase AtPK1/AtPK6... 154 2e-036
sp|P21137|KAPC_CAEEL cAMP-dependent protein kinase catalytic sub... 148 1e-034
sp|P54644|KRAC_DICDI RAC family serine/threonine-protein kinase ... 148 1e-034
sp|Q2LZZ7|TRC_DROPS Serine/threonine-protein kinase tricorner OS... 144 1e-033
sp|Q9NBK5|TRC_DROME Serine/threonine-protein kinase tricorner OS... 144 2e-033
sp|P17612|KAPCA_HUMAN cAMP-dependent protein kinase catalytic su... 143 3e-033
sp|P68180|KAPCB_CRIGR cAMP-dependent protein kinase catalytic su... 143 3e-033
sp|P68181|KAPCB_MOUSE cAMP-dependent protein kinase catalytic su... 143 3e-033
sp|P68182|KAPCB_RAT cAMP-dependent protein kinase catalytic subu... 143 3e-033
sp|P05132|KAPCA_MOUSE cAMP-dependent protein kinase catalytic su... 143 4e-033
sp|P05986|KAPC_YEAST cAMP-dependent protein kinase type 3 OS=Sac... 143 4e-033
sp|P25321|KAPCA_CRIGR cAMP-dependent protein kinase catalytic su... 142 6e-033
>sp|Q54PK9|PDPKB_DICDI 3-phosphoinositide-dependent protein kinase B
OS=Dictyostelium discoideum GN=pdkB PE=3 SV=1
Length = 908
Score = 244 bits (622), Expect = 1e-063
Identities = 125/304 (41%), Positives = 183/304 (60%), Gaps = 18/304 (5%)
Frame = +1
Query: 325 SIQDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVKLERIVLDQL 504
S DF+ + G G+Y KV +KE ++A KI++KK IIKE K YV E+ +LD L
Sbjct: 267 SRSDFDFIRTIGKGAYGKVKLVIEKETQLIFASKILNKKLIIKEKKAKYVNTEKTILDSL 326
Query: 505 DHPGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQVVDALEYIH 684
D+P I+KLF+TFQD +LY LE C G+L + + G S D RFY+A+++ ALEY+H
Sbjct: 327 DNPNIVKLFYTFQDENNLYFILEYCPNGDLLGALKKAGCFSIDVVRFYAAEILIALEYLH 386
Query: 685 NMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITLLPNASSDDKACTFVGTAAYV 864
G+ HRD+KPEN+LL + H+K++DFGS K + + + ++ +F GTA YV
Sbjct: 387 GKGIAHRDLKPENILLGKNQHLKLSDFGSAKQLS------IGSHHKGSRSGSFCGTAEYV 440
Query: 865 PPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNHFSEAA 1044
PE+L A D+W+ GC LYQ++SG PFK +E+ F I R+ +P++F +
Sbjct: 441 CPELLTEKSAGVEADIWSYGCLLYQLVSGKLPFKGFNEYQTFLLITKREFSYPDNFDKCC 500
Query: 1045 RDLIDRLLDTDPSRRPGAGSEGYASLKRHPFFKGV-DWKNVRSQTPPKL------APDPS 1203
+LID+LLD DP +RP + +K H FF + DW ++ SQTPP + +P PS
Sbjct: 501 MNLIDQLLDLDPYKRP-----TISEIKNHEFFSSIQDWSSIPSQTPPPIEQMVPQSPFPS 555
Query: 1204 SQSA 1215
S+
Sbjct: 556 PNSS 559
>sp|P34102|PK3_DICDI Protein kinase 3 OS=Dictyostelium discoideum GN=pkgC PE=3
SV=2
Length = 910
Score = 226 bits (575), Expect = 3e-058
Identities = 118/320 (36%), Positives = 197/320 (61%), Gaps = 7/320 (2%)
Frame = +1
Query: 235 FDSKLTLQGNDGASISRSKSFAFKAPQ--ENFSIQDFELDKIYGVGSYSKVVRAKKKENG 408
FD+ L + + +S SKS K Q + +I DFEL K+ GVGS+ +V ++K+ G
Sbjct: 463 FDN-LEVSSSSDRDLSSSKSLNKKNKQSIKKLTIDDFELLKVLGVGSFGRVYLVRRKDTG 521
Query: 409 AVYAMKIMDKKFIIKENKTAYVKLERIVLDQLDHPGIIKLFFTFQDSFSLYMALESCEGG 588
YAMK+++KK ++K+ + A+ E++VL +DHP I++L F FQ+ L+M ++ GG
Sbjct: 522 KFYAMKVLNKKDMLKKKQIAHTNTEKMVLSTMDHPFIVRLHFAFQNEDFLFMCMDYVPGG 581
Query: 589 ELFDQITRKGRLSEDEARFYSAQVVDALEYIHNMGLIHRDIKPENLLLTSDGHIKIADFG 768
ELF + + G+ E+ A+FY A+V+ +L Y+H+ +I+RDIKPEN+LL +GHIK+ DFG
Sbjct: 582 ELFHHLQKAGKFPEELAKFYIAEVICSLHYLHSNNIIYRDIKPENILLDEEGHIKLTDFG 641
Query: 769 SVKPMQDSQITLLPNASSDDKACTFVGTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLS 948
K S + N A TF GT Y+ PE++ + D W++G L++ML+
Sbjct: 642 LSKSGITS-VVGSKNGGEGGFATTFCGTPEYLAPEIITGAGHGKAADWWSVGILLFEMLT 700
Query: 949 GTSPFKDASEWLIFQRIIARDIKFPNHFSEAARDLIDRLLDTDPSRRPGAGSEGYASLKR 1128
G SPF ++ +++ +I +++ P S A+DL+++LL DP++R G+ ++G+ +
Sbjct: 701 GRSPFLASNRNDMYKSMIQGNLRMPMFLSSDAQDLLEKLLVPDPNKRLGS-TQGFEEISS 759
Query: 1129 HPFFKGVDWKNVRSQ--TPP 1182
HPFF+ + W+ + S+ TPP
Sbjct: 760 HPFFELIPWRMLESKMITPP 779
>sp|Q39030|KPK19_ARATH Serine/threonine-protein kinase AtPK19 OS=Arabidopsis
thaliana GN=ATPK19 PE=2 SV=2
Length = 471
Score = 222 bits (564), Expect = 6e-057
Identities = 117/342 (34%), Positives = 194/342 (56%), Gaps = 23/342 (6%)
Frame = +1
Query: 217 MTMEKEFDSKLTLQGNDGASISRSKSF-------AFKAPQE---NFSIQDFELDKIYGVG 366
+T+ + DS ++ +G SI + F + K+P+E I+DFE+ K+ G G
Sbjct: 90 LTLRETEDSVDLVECVEGESIKENDEFSGNDDTDSEKSPEEVSGVVGIEDFEVLKVVGQG 149
Query: 367 SYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVKLERIVLDQLDHPGIIKLFFTFQD 546
++ KV + +KK+ +YAMK+M K I+++N Y+K ER +L ++DHP I++L ++FQ
Sbjct: 150 AFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKIDHPFIVQLKYSFQT 209
Query: 547 SFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQVVDALEYIHNMGLIHRDIKPENL 726
+ LY+ L+ GG LF Q+ +G ED AR Y+A++V A+ ++H G++HRD+KPEN+
Sbjct: 210 KYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENI 269
Query: 727 LLTSDGHIKIADFGSVKPMQDSQITLLPNASSDDKACTFVGTAAYVPPEVLNSSPATFGN 906
L+ DGH+ + DFG K ++ + ++ + GT Y+ PE++
Sbjct: 270 LMDVDGHVMLTDFGLAKEFEE-----------NTRSNSMCGTTEYMAPEIVRGKGHDKAA 318
Query: 907 DLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNHFSEAARDLIDRLLDTDPSR 1086
D W++G LY+ML+G PF S+ I Q+I+ IK P S A L+ LL +P R
Sbjct: 319 DWWSVGILLYEMLTGKPPFL-GSKGKIQQKIVKDKIKLPQFLSNEAHALLKGLLQKEPER 377
Query: 1087 RPGAGSEGYASLKRHPFFKGVDWKNVRS-QTPPKLAPDPSSQ 1209
R G+G G +K+H +FK ++WK + + + P P S +
Sbjct: 378 RLGSGPSGAEEIKKHKWFKAINWKKLEAREVQPSFKPAVSGR 419
>sp|O15530|PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 OS=Homo
sapiens GN=PDPK1 PE=1 SV=1
Length = 556
Score = 158 bits (397), Expect = 1e-037
Identities = 76/149 (51%), Positives = 100/149 (67%)
Frame = +1
Query: 331 QDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVKLERIVLDQLDH 510
+DF+ KI G GS+S VV A++ YA+KI++K+ IIKENK YV ER V+ +LDH
Sbjct: 80 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 139
Query: 511 PGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQVVDALEYIHNM 690
P +KL+FTFQD LY L + GEL I + G E RFY+A++V ALEY+H
Sbjct: 140 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGK 199
Query: 691 GLIHRDIKPENLLLTSDGHIKIADFGSVK 777
G+IHRD+KPEN+LL D HI+I DFG+ K
Sbjct: 200 GIIHRDLKPENILLNEDMHIQITDFGTAK 228
>sp|Q9Z2A0|PDPK1_MOUSE 3-phosphoinositide-dependent protein kinase 1 OS=Mus
musculus GN=Pdpk1 PE=1 SV=2
Length = 559
Score = 158 bits (397), Expect = 1e-037
Identities = 76/149 (51%), Positives = 100/149 (67%)
Frame = +1
Query: 331 QDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVKLERIVLDQLDH 510
+DF+ KI G GS+S VV A++ YA+KI++K+ IIKENK YV ER V+ +LDH
Sbjct: 83 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 142
Query: 511 PGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQVVDALEYIHNM 690
P +KL+FTFQD LY L + GEL I + G E RFY+A++V ALEY+H
Sbjct: 143 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGK 202
Query: 691 GLIHRDIKPENLLLTSDGHIKIADFGSVK 777
G+IHRD+KPEN+LL D HI+I DFG+ K
Sbjct: 203 GIIHRDLKPENILLNEDMHIQITDFGTAK 231
>sp|O55173|PDPK1_RAT 3-phosphoinositide-dependent protein kinase 1 OS=Rattus
norvegicus GN=Pdpk1 PE=2 SV=1
Length = 559
Score = 158 bits (397), Expect = 1e-037
Identities = 76/149 (51%), Positives = 100/149 (67%)
Frame = +1
Query: 331 QDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVKLERIVLDQLDH 510
+DF+ KI G GS+S VV A++ YA+KI++K+ IIKENK YV ER V+ +LDH
Sbjct: 83 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 142
Query: 511 PGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQVVDALEYIHNM 690
P +KL+FTFQD LY L + GEL I + G E RFY+A++V ALEY+H
Sbjct: 143 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGK 202
Query: 691 GLIHRDIKPENLLLTSDGHIKIADFGSVK 777
G+IHRD+KPEN+LL D HI+I DFG+ K
Sbjct: 203 GIIHRDLKPENILLNEDMHIQITDFGTAK 231
>sp|Q6A1A2|PDPK2_HUMAN Putative 3-phosphoinositide-dependent protein kinase 2
OS=Homo sapiens GN=PDPK2 PE=5 SV=1
Length = 396
Score = 155 bits (391), Expect = 7e-037
Identities = 75/149 (50%), Positives = 100/149 (67%)
Frame = +1
Query: 331 QDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVKLERIVLDQLDH 510
+DF+ KI G GS+S VV A++ YA+KI++K+ IIKENK YV ER V+ +LDH
Sbjct: 53 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 112
Query: 511 PGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQVVDALEYIHNM 690
P +KL+FTFQD LY L + GEL I + G E RFY+A++V ALEY+H
Sbjct: 113 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGK 172
Query: 691 GLIHRDIKPENLLLTSDGHIKIADFGSVK 777
G+IHRD+KPEN+LL D +I+I DFG+ K
Sbjct: 173 GIIHRDLKPENILLNEDMYIQITDFGTAK 201
>sp|Q54TW2|PDPKA_DICDI Probable serine/threonine-protein kinase pdkA
OS=Dictyostelium discoideum GN=pdkA PE=3 SV=1
Length = 686
Score = 154 bits (388), Expect = 1e-036
Identities = 73/160 (45%), Positives = 108/160 (67%), Gaps = 3/160 (1%)
Frame = +1
Query: 325 SIQDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVKLERIVLDQL 504
+I+DF + K+ G GSY VV +KE YA+KI++KK IIKENK YV++E+ + +
Sbjct: 65 TIEDFIIGKVLGEGSYGAVVLGTEKETQQQYAIKILEKKQIIKENKIKYVQIEKEIFCKS 124
Query: 505 DHPGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQVVDALEYIH 684
+HP I+KLFFTF+ LY LE C G+L QI + G ++Y A+++ LE++H
Sbjct: 125 NHPNIVKLFFTFRSEQCLYYVLELCSQGDLLHQIKKVGSFDYRSCQYYVAEIISGLEHLH 184
Query: 685 NMGLIHRDIKPENLLLTSDGHIKIADFGSVK---PMQDSQ 795
++G++HRD+KPEN+L++SD H+KI DFG+ K P Q SQ
Sbjct: 185 SLGIVHRDLKPENILMSSDLHVKITDFGTGKILPPPQSSQ 224
>sp|P42818|KPK1_ARATH Serine/threonine-protein kinase AtPK1/AtPK6 OS=Arabidopsis
thaliana GN=ATPK1 PE=1 SV=1
Length = 465
Score = 154 bits (387), Expect = 2e-036
Identities = 66/155 (42%), Positives = 107/155 (69%)
Frame = +1
Query: 328 IQDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVKLERIVLDQLD 507
I DFE+ K+ G G++ KV + +KKE +YAMK+M K I+++N Y+K ER +L ++D
Sbjct: 131 IDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKID 190
Query: 508 HPGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQVVDALEYIHN 687
HP I++L ++FQ + LY+ L+ GG LF Q+ +G ED AR Y+A++V A+ ++H
Sbjct: 191 HPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHE 250
Query: 688 MGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDS 792
G++HRD+KPEN+L+ +DGH+ + DFG K +++
Sbjct: 251 KGIMHRDLKPENILMDTDGHVMLTDFGLAKEFEEN 285
>sp|P21137|KAPC_CAEEL cAMP-dependent protein kinase catalytic subunit
OS=Caenorhabditis elegans GN=kin-1 PE=2 SV=3
Length = 404
Score = 148 bits (372), Expect = 1e-034
Identities = 70/164 (42%), Positives = 108/164 (65%)
Frame = +1
Query: 313 QENFSIQDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVKLERIV 492
Q + DF+ K G GS+ +V+ K K++G YAMKI+DK+ ++K + + E+ +
Sbjct: 73 QNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRI 132
Query: 493 LDQLDHPGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQVVDAL 672
L +D P ++ + F+F+D+ +LYM LE GGE+F + R GR SE +RFY+AQ+V A
Sbjct: 133 LQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAF 192
Query: 673 EYIHNMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITL 804
EY+H++ LI+RD+KPENLL+ S G++KI DFG K ++ TL
Sbjct: 193 EYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTL 236
>sp|P54644|KRAC_DICDI RAC family serine/threonine-protein kinase homolog
OS=Dictyostelium discoideum GN=pkbA PE=1 SV=1
Length = 444
Score = 148 bits (372), Expect = 1e-034
Identities = 67/154 (43%), Positives = 104/154 (67%)
Frame = +1
Query: 316 ENFSIQDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVKLERIVL 495
E + DFEL + G GS+ KV++ +KK+ G VYAMK++ KK I++ N+ + ER +L
Sbjct: 113 EKVGVADFELLNLVGKGSFGKVIQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSERNIL 172
Query: 496 DQLDHPGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQVVDALE 675
+++HP ++ L ++FQ LY L+ GGELF + + + +ED R+Y A++V ALE
Sbjct: 173 QKINHPFLVNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVLALE 232
Query: 676 YIHNMGLIHRDIKPENLLLTSDGHIKIADFGSVK 777
++H G+I+RD+KPENLLLT++GHI + DFG K
Sbjct: 233 HLHLSGVIYRDLKPENLLLTNEGHICMTDFGLCK 266
>sp|Q2LZZ7|TRC_DROPS Serine/threonine-protein kinase tricorner OS=Drosophila
pseudoobscura pseudoobscura GN=trc PE=3 SV=1
Length = 458
Score = 144 bits (363), Expect = 1e-033
Identities = 68/177 (38%), Positives = 114/177 (64%)
Frame = +1
Query: 328 IQDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVKLERIVLDQLD 507
++DFE K+ G G++ +V +KK+ G VYAMK++ K ++++ + A+V+ ER VL + D
Sbjct: 89 VEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEAD 148
Query: 508 HPGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQVVDALEYIHN 687
H ++K++++FQD +LY+ +E GG++ + +K LSE+ +FY ++ A++ IH
Sbjct: 149 HQWVVKMYYSFQDQVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHK 208
Query: 688 MGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITLLPNASSDDKACTFVGTAA 858
+G IHRDIKP+NLLL + GH+K++DFG ++ S T S K F+GT A
Sbjct: 209 LGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCA 265
>sp|Q9NBK5|TRC_DROME Serine/threonine-protein kinase tricorner OS=Drosophila
melanogaster GN=trc PE=1 SV=1
Length = 463
Score = 144 bits (362), Expect = 2e-033
Identities = 68/177 (38%), Positives = 114/177 (64%)
Frame = +1
Query: 328 IQDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVKLERIVLDQLD 507
++DFE K+ G G++ +V +KK+ G VYAMK++ K ++++ + A+V+ ER VL + D
Sbjct: 90 VEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEAD 149
Query: 508 HPGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQVVDALEYIHN 687
H ++K++++FQD +LY+ +E GG++ + +K LSE+ +FY ++ A++ IH
Sbjct: 150 HQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHK 209
Query: 688 MGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITLLPNASSDDKACTFVGTAA 858
+G IHRDIKP+NLLL + GH+K++DFG ++ S T S K F+GT A
Sbjct: 210 LGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCA 266
>sp|P17612|KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha
OS=Homo sapiens GN=PRKACA PE=1 SV=2
Length = 351
Score = 143 bits (360), Expect = 3e-033
Identities = 70/169 (41%), Positives = 111/169 (65%), Gaps = 1/169 (0%)
Frame = +1
Query: 301 FKAPQENFS-IQDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVK 477
+++P +N + + FE K G GS+ +V+ K KE G YAMKI+DK+ ++K + +
Sbjct: 31 WESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTL 90
Query: 478 LERIVLDQLDHPGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQ 657
E+ +L ++ P ++KL F+F+D+ +LYM +E GGE+F + R GR SE ARFY+AQ
Sbjct: 91 NEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 150
Query: 658 VVDALEYIHNMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITL 804
+V EY+H++ LI+RD+KPENLL+ G+I++ DFG K ++ TL
Sbjct: 151 IVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTL 199
>sp|P68180|KAPCB_CRIGR cAMP-dependent protein kinase catalytic subunit beta
OS=Cricetulus griseus GN=PRKACB PE=2 SV=2
Length = 351
Score = 143 bits (359), Expect = 3e-033
Identities = 67/165 (40%), Positives = 106/165 (64%)
Frame = +1
Query: 310 PQENFSIQDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVKLERI 489
P N ++DFE K G GS+ +V+ K K YAMKI+DK+ ++K + + E+
Sbjct: 35 PPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKR 94
Query: 490 VLDQLDHPGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQVVDA 669
+L ++ P +++L ++F+D+ +LYM +E GGE+F + R GR SE ARFY+AQ+V
Sbjct: 95 ILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLT 154
Query: 670 LEYIHNMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITL 804
EY+H++ LI+RD+KPENLL+ G+I++ DFG K ++ TL
Sbjct: 155 FEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTL 199
>sp|P68181|KAPCB_MOUSE cAMP-dependent protein kinase catalytic subunit beta
OS=Mus musculus GN=Prkacb PE=1 SV=2
Length = 351
Score = 143 bits (359), Expect = 3e-033
Identities = 67/165 (40%), Positives = 106/165 (64%)
Frame = +1
Query: 310 PQENFSIQDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVKLERI 489
P N ++DFE K G GS+ +V+ K K YAMKI+DK+ ++K + + E+
Sbjct: 35 PPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKR 94
Query: 490 VLDQLDHPGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQVVDA 669
+L ++ P +++L ++F+D+ +LYM +E GGE+F + R GR SE ARFY+AQ+V
Sbjct: 95 ILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLT 154
Query: 670 LEYIHNMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITL 804
EY+H++ LI+RD+KPENLL+ G+I++ DFG K ++ TL
Sbjct: 155 FEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTL 199
>sp|P68182|KAPCB_RAT cAMP-dependent protein kinase catalytic subunit beta
OS=Rattus norvegicus GN=Prkacb PE=1 SV=2
Length = 351
Score = 143 bits (359), Expect = 3e-033
Identities = 67/165 (40%), Positives = 106/165 (64%)
Frame = +1
Query: 310 PQENFSIQDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVKLERI 489
P N ++DFE K G GS+ +V+ K K YAMKI+DK+ ++K + + E+
Sbjct: 35 PPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKR 94
Query: 490 VLDQLDHPGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQVVDA 669
+L ++ P +++L ++F+D+ +LYM +E GGE+F + R GR SE ARFY+AQ+V
Sbjct: 95 ILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLT 154
Query: 670 LEYIHNMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITL 804
EY+H++ LI+RD+KPENLL+ G+I++ DFG K ++ TL
Sbjct: 155 FEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTL 199
>sp|P05132|KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha
OS=Mus musculus GN=Prkaca PE=1 SV=3
Length = 351
Score = 143 bits (358), Expect = 4e-033
Identities = 69/169 (40%), Positives = 111/169 (65%), Gaps = 1/169 (0%)
Frame = +1
Query: 301 FKAPQENFS-IQDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVK 477
++ P +N + + F+ K G GS+ +V+ K KE+G YAMKI+DK+ ++K + +
Sbjct: 31 WETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTL 90
Query: 478 LERIVLDQLDHPGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQ 657
E+ +L ++ P ++KL F+F+D+ +LYM +E GGE+F + R GR SE ARFY+AQ
Sbjct: 91 NEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQ 150
Query: 658 VVDALEYIHNMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITL 804
+V EY+H++ LI+RD+KPENLL+ G+I++ DFG K ++ TL
Sbjct: 151 IVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTL 199
>sp|P05986|KAPC_YEAST cAMP-dependent protein kinase type 3 OS=Saccharomyces
cerevisiae GN=TPK3 PE=1 SV=2
Length = 398
Score = 143 bits (358), Expect = 4e-033
Identities = 73/206 (35%), Positives = 118/206 (57%)
Frame = +1
Query: 187 VEEEEESSSLMTMEKEFDSKLTLQGNDGASISRSKSFAFKAPQENFSIQDFELDKIYGVG 366
V EE S++ + + KL + + G + + ++ +S+ DF++ + G G
Sbjct: 38 VHEECSSNTPVEINGRNSGKLKEEASAGICLVKKPMLQYRDTSGKYSLSDFQILRTLGTG 97
Query: 367 SYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVKLERIVLDQLDHPGIIKLFFTFQD 546
S+ +V + NG YA+K + K I+K + + ER +L + HP II+++ TFQD
Sbjct: 98 SFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQD 157
Query: 547 SFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQVVDALEYIHNMGLIHRDIKPENL 726
S ++M ++ EGGELF + + R A+FY+A+V ALEY+H+ +I+RD+KPEN+
Sbjct: 158 SQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENI 217
Query: 727 LLTSDGHIKIADFGSVKPMQDSQITL 804
LL +GHIKI DFG K + D TL
Sbjct: 218 LLDKNGHIKITDFGFAKYVPDVTYTL 243
>sp|P25321|KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha
OS=Cricetulus griseus GN=PRKACA PE=2 SV=2
Length = 351
Score = 142 bits (357), Expect = 6e-033
Identities = 69/169 (40%), Positives = 111/169 (65%), Gaps = 1/169 (0%)
Frame = +1
Query: 301 FKAPQENFS-IQDFELDKIYGVGSYSKVVRAKKKENGAVYAMKIMDKKFIIKENKTAYVK 477
+++P +N + + F+ K G GS+ +V+ K KE G YAMKI+DK+ ++K + +
Sbjct: 31 WESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTL 90
Query: 478 LERIVLDQLDHPGIIKLFFTFQDSFSLYMALESCEGGELFDQITRKGRLSEDEARFYSAQ 657
E+ +L ++ P ++KL F+F+D+ +LYM +E GGE+F + R GR SE ARFY+AQ
Sbjct: 91 NEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 150
Query: 658 VVDALEYIHNMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITL 804
+V EY+H++ LI+RD+KPENLL+ G+I++ DFG K ++ TL
Sbjct: 151 IVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTL 199
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,077,717,681
Number of Sequences: 518415
Number of Extensions: 17077717681
Number of Successful Extensions: 110867487
Number of sequences better than 0.0: 0
|
