BLASTX 7.6.2
Query= UN04646 /QuerySize=1362
(1361 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8HXY2|MCAT_MACFA Mitochondrial carnitine/acylcarnitine carri... 150 2e-035
sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine carri... 149 7e-035
sp|Q9Z2Z6|MCAT_MOUSE Mitochondrial carnitine/acylcarnitine carri... 147 3e-034
sp|P97521|MCAT_RAT Mitochondrial carnitine/acylcarnitine carrier... 142 7e-033
sp|Q0V7M4|SCMC2_BOVIN Calcium-binding mitochondrial carrier prot... 92 1e-017
sp|A2ASZ8|SCMC2_MOUSE Calcium-binding mitochondrial carrier prot... 90 3e-017
sp|Q5XHA0|SCMC1_XENTR Calcium-binding mitochondrial carrier prot... 87 3e-016
sp|Q7T0U6|SCM1B_XENLA Calcium-binding mitochondrial carrier prot... 86 6e-016
sp|O18757|SCMC1_RABIT Calcium-binding mitochondrial carrier prot... 86 7e-016
sp|Q6KCM7|SCMC2_HUMAN Calcium-binding mitochondrial carrier prot... 86 7e-016
sp|Q6NUK1|SCMC1_HUMAN Calcium-binding mitochondrial carrier prot... 85 1e-015
sp|Q7ZY36|SCM1A_XENLA Calcium-binding mitochondrial carrier prot... 85 1e-015
sp|A5PJZ1|SCMC1_BOVIN Calcium-binding mitochondrial carrier prot... 84 2e-015
sp|Q7ZYD5|SCMC2_XENLA Calcium-binding mitochondrial carrier prot... 84 3e-015
sp|A5DIS9|TPC1_PICGU Mitochondrial thiamine pyrophosphate carrie... 81 1e-014
sp|Q8BMD8|SCMC1_MOUSE Calcium-binding mitochondrial carrier prot... 81 2e-014
sp|Q8BW66|MCP62_MOUSE Putative mitochondrial carrier protein FLJ... 80 2e-014
sp|Q9BV35|SCMC3_HUMAN Calcium-binding mitochondrial carrier prot... 79 5e-014
sp|Q3MHI3|MCP62_BOVIN Putative mitochondrial carrier protein FLJ... 77 3e-013
sp|A4QNX2|HDCPB_DANRE Hepatocellular carcinoma down-regulated mi... 75 1e-012
>sp|Q8HXY2|MCAT_MACFA Mitochondrial carnitine/acylcarnitine carrier protein
OS=Macaca fascicularis GN=SLC25A20 PE=2 SV=1
Length = 301
Score = 150 bits (378), Expect = 2e-035
Identities = 90/241 (37%), Positives = 135/241 (56%), Gaps = 8/241 (3%)
Frame = +2
Query: 383 FTILRRMLAVEGPASLYRGMAAPLASVTFQNAMVFQIYAILSRSFDSSLPLEEPPSYRGV 562
F R+ L EG LYRGMAAP+ VT A+ F + L + P E+ SY +
Sbjct: 56 FDCFRKTLFREGIRGLYRGMAAPIIGVTPMFAVCFFGFG-LGKKLQQKHP-EDVLSYPQL 113
Query: 563 ALGGVGTGAVQSLLLSPVELIKIRLQLQQSN-----SGPICLAKTILRREGLKGIYKGLT 727
G+ +G + +++P E IK LQ+Q S+ +G + AK + + G++GIYKG
Sbjct: 114 FAAGMLSGIFTTGIMTPGERIKCLLQIQASSGETKYTGTLDCAKKLYQEFGIRGIYKGTV 173
Query: 728 ITVLRDAPAHGLYFWTYEYVRERLHPGCRKSGEETLRTMLVAGGLAGVSSWVVCYPLDVV 907
+T++RD PA G+YF TYE+V+ P ++ E ++ +LVAGG+AG+ +W V P DV+
Sbjct: 174 VTLMRDVPASGMYFMTYEWVKNIFTPEGKRVSELSVPRVLVAGGIAGIFNWAVAIPPDVL 233
Query: 908 KTRLQQGNHGSY-DGITDCFRKSIAQEGYGVLWRGLGTAVARAFVVNGAIFAAYEVALRC 1084
K+R Q G Y +G D R+ I EG L++G + RAF N A F +EVA++
Sbjct: 234 KSRFQTAPPGKYPNGFRDVLRELIPDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKF 293
Query: 1085 L 1087
L
Sbjct: 294 L 294
>sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine carrier protein
OS=Homo sapiens GN=SLC25A20 PE=1 SV=1
Length = 301
Score = 149 bits (374), Expect = 7e-035
Identities = 89/241 (36%), Positives = 134/241 (55%), Gaps = 8/241 (3%)
Frame = +2
Query: 383 FTILRRMLAVEGPASLYRGMAAPLASVTFQNAMVFQIYAILSRSFDSSLPLEEPPSYRGV 562
F R+ L EG LYRGMAAP+ VT A+ F + L + P E+ SY +
Sbjct: 56 FDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFG-LGKKLQQKHP-EDVLSYPQL 113
Query: 563 ALGGVGTGAVQSLLLSPVELIKIRLQLQQSN-----SGPICLAKTILRREGLKGIYKGLT 727
G+ +G + +++P E IK LQ+Q S+ +G + AK + + G++GIYKG
Sbjct: 114 FAAGMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTV 173
Query: 728 ITVLRDAPAHGLYFWTYEYVRERLHPGCRKSGEETLRTMLVAGGLAGVSSWVVCYPLDVV 907
+T++RD PA G+YF TYE+++ P ++ E + +LVAGG+AG+ +W V P DV+
Sbjct: 174 LTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVL 233
Query: 908 KTRLQQGNHGSY-DGITDCFRKSIAQEGYGVLWRGLGTAVARAFVVNGAIFAAYEVALRC 1084
K+R Q G Y +G D R+ I EG L++G + RAF N A F +EVA++
Sbjct: 234 KSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKF 293
Query: 1085 L 1087
L
Sbjct: 294 L 294
>sp|Q9Z2Z6|MCAT_MOUSE Mitochondrial carnitine/acylcarnitine carrier protein
OS=Mus musculus GN=Slc25a20 PE=1 SV=1
Length = 301
Score = 147 bits (369), Expect = 3e-034
Identities = 86/237 (36%), Positives = 132/237 (55%), Gaps = 8/237 (3%)
Frame = +2
Query: 395 RRMLAVEGPASLYRGMAAPLASVTFQNAMVFQIYAILSRSFDSSLPLEEPPSYRGVALGG 574
R+ L EG LYRGMAAP+ VT A+ F + L + P E+ SY + G
Sbjct: 60 RKTLMREGITGLYRGMAAPIIGVTPMFAVCFFGFG-LGKKLQQKSP-EDELSYPQLFTAG 117
Query: 575 VGTGAVQSLLLSPVELIKIRLQLQQSN-----SGPICLAKTILRREGLKGIYKGLTITVL 739
+ +G + +++P E IK LQ+Q S+ SG + AK + + G++G YKG +T++
Sbjct: 118 MLSGVFTTGIMTPGERIKCLLQIQASSGENKYSGTLDCAKKLYQEFGIRGFYKGTVLTLM 177
Query: 740 RDAPAHGLYFWTYEYVRERLHPGCRKSGEETLRTMLVAGGLAGVSSWVVCYPLDVVKTRL 919
RD PA G+YF TYE+++ P + + ++ +LVAGG AG+ +W V P DV+K+R
Sbjct: 178 RDVPASGMYFMTYEWLKNLFTPEGKSVSDLSVPRILVAGGFAGIFNWAVAIPPDVLKSRF 237
Query: 920 QQGNHGSY-DGITDCFRKSIAQEGYGVLWRGLGTAVARAFVVNGAIFAAYEVALRCL 1087
Q G Y +G D R+ I +EG L++G + RAF N A F +E+A++ L
Sbjct: 238 QTAPPGKYPNGFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACFLGFEIAMKFL 294
>sp|P97521|MCAT_RAT Mitochondrial carnitine/acylcarnitine carrier protein
OS=Rattus norvegicus GN=Slc25a20 PE=1 SV=1
Length = 301
Score = 142 bits (357), Expect = 7e-033
Identities = 84/237 (35%), Positives = 131/237 (55%), Gaps = 8/237 (3%)
Frame = +2
Query: 395 RRMLAVEGPASLYRGMAAPLASVTFQNAMVFQIYAILSRSFDSSLPLEEPPSYRGVALGG 574
R+ L EG LYRGMAAP+ VT A+ F + + R S E+ +Y + G
Sbjct: 60 RKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKRLQQKS--PEDELTYPQLFTAG 117
Query: 575 VGTGAVQSLLLSPVELIKIRLQLQQSN-----SGPICLAKTILRREGLKGIYKGLTITVL 739
+ +G + +++P E IK LQ+Q S+ SG + AK + + G++G YKG +T++
Sbjct: 118 MLSGVFTTGIMTPGERIKCLLQIQASSGKNKYSGTLDCAKKLYQEFGIRGFYKGTALTLM 177
Query: 740 RDAPAHGLYFWTYEYVRERLHPGCRKSGEETLRTMLVAGGLAGVSSWVVCYPLDVVKTRL 919
RD PA G+YF TYE+++ P + + ++ +LVAGG G+ +WVV P DV+K+R
Sbjct: 178 RDVPASGMYFMTYEWLKNLFTPQGKSVHDLSVPRVLVAGGFRGIFNWVVAIPPDVLKSRF 237
Query: 920 QQGNHGSY-DGITDCFRKSIAQEGYGVLWRGLGTAVARAFVVNGAIFAAYEVALRCL 1087
Q G Y +G D R+ I +EG L++G + RAF N A F +E+ ++ L
Sbjct: 238 QTAPPGKYPNGFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACFLGFEIPMKIL 294
>sp|Q0V7M4|SCMC2_BOVIN Calcium-binding mitochondrial carrier protein SCaMC-2
OS=Bos taurus GN=SLC25A25 PE=2 SV=1
Length = 469
Score = 92 bits (226), Expect = 1e-017
Identities = 57/178 (32%), Positives = 91/178 (51%), Gaps = 11/178 (6%)
Frame = +2
Query: 551 YRGVALGGVGTGAVQSLLLSPVELIKIRLQLQQSNSGPICLA---KTILRREGLKGIYKG 721
+R + GG G GAV +P++ +K+ +Q+ S S +C+ ++R G + +++G
Sbjct: 187 WRHLVAGG-GAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIVGGFTQMIREGGARSLWRG 245
Query: 722 LTITVLRDAPAHGLYFWTYEYVRERLHPGCRKSGEETLR--TMLVAGGLAGVSSWVVCYP 895
I VL+ AP + F YE ++ + S +ETLR LVAG LAG + YP
Sbjct: 246 NGINVLKIAPESAIKFMAYEQIKRLI-----GSDQETLRIHERLVAGSLAGAIAQSSIYP 300
Query: 896 LDVVKTRLQQGNHGSYDGITDCFRKSIAQEGYGVLWRGLGTAVARAFVVNGAIFAAYE 1069
++V+KTR+ G Y G+ DC RK +A+EG ++G + G A YE
Sbjct: 301 MEVLKTRMALRKTGQYSGMLDCARKILAREGMAAFYKGYVPNMLGIIPYAGIDLAVYE 358
>sp|A2ASZ8|SCMC2_MOUSE Calcium-binding mitochondrial carrier protein SCaMC-2
OS=Mus musculus GN=Slc25a25 PE=2 SV=1
Length = 469
Score = 90 bits (222), Expect = 3e-017
Identities = 57/178 (32%), Positives = 91/178 (51%), Gaps = 11/178 (6%)
Frame = +2
Query: 551 YRGVALGGVGTGAVQSLLLSPVELIKIRLQLQQSNSGPICLA---KTILRREGLKGIYKG 721
+R + GG G GAV +P++ +K+ +Q+ S S +C+ ++R G K +++G
Sbjct: 187 WRHLVAGG-GAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIVGGFTQMIREGGAKSLWRG 245
Query: 722 LTITVLRDAPAHGLYFWTYEYVRERLHPGCRKSGEETLR--TMLVAGGLAGVSSWVVCYP 895
I VL+ AP + F YE ++ + S +ETLR LVAG LAG + YP
Sbjct: 246 NGINVLKIAPESAIKFMAYEQMKRLV-----GSDQETLRIHERLVAGSLAGAIAQSSIYP 300
Query: 896 LDVVKTRLQQGNHGSYDGITDCFRKSIAQEGYGVLWRGLGTAVARAFVVNGAIFAAYE 1069
++V+KTR+ G Y G+ DC R+ +A+EG ++G + G A YE
Sbjct: 301 MEVLKTRMALRKTGQYSGMLDCARRILAKEGVAAFYKGYIPNMLGIIPYAGIDLAVYE 358
>sp|Q5XHA0|SCMC1_XENTR Calcium-binding mitochondrial carrier protein SCaMC-1
OS=Xenopus tropicalis GN=slc25a24 PE=2 SV=1
Length = 473
Score = 87 bits (213), Expect = 3e-016
Identities = 54/187 (28%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Frame = +2
Query: 566 LGGVGTGAVQSLLLSPVELIKIRLQLQQS--NSGPICLAKTILRREGLKGIYKGLTITVL 739
L G GAV +P++ +K+ +Q+ S N+ I K +++ G++ +++G + V+
Sbjct: 199 LAGGMAGAVSRTGTAPLDRLKVMMQVHGSKGNANIITGLKQMVKEGGIRSLWRGNGVNVI 258
Query: 740 RDAPAHGLYFWTYEYVRERLHPGCRKSGEETLRTMLVAGGLAGVSSWVVCYPLDVVKTRL 919
+ AP + FW YE ++ +SG+ +AG LAG ++ YP++V+KTRL
Sbjct: 259 KIAPETAMKFWAYEQYKKLF---TSESGKLGTAERFIAGSLAGATAQTSIYPMEVLKTRL 315
Query: 920 QQGNHGSYDGITDCFRKSIAQEGYGVLWRGLGTAVARAFVVNGAIFAAYEVALRCLFPQL 1099
G G Y G+ DC +K + +EG ++G + G A YE L+ + Q
Sbjct: 316 AVGKTGQYSGMFDCAKKIMQREGVRAFYKGYIPNILGIIPYAGIDLAIYE-TLKTFWLQN 374
Query: 1100 TSADVAN 1120
+ D AN
Sbjct: 375 YATDSAN 381
>sp|Q7T0U6|SCM1B_XENLA Calcium-binding mitochondrial carrier protein SCaMC-1-B
OS=Xenopus laevis GN=slc25a24-b PE=2 SV=1
Length = 473
Score = 86 bits (211), Expect = 6e-016
Identities = 55/187 (29%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Frame = +2
Query: 566 LGGVGTGAVQSLLLSPVELIKIRLQLQQS--NSGPICLAKTILRREGLKGIYKGLTITVL 739
+ G GAV +P++ +K+ +Q+ S NS I K +++ G++ +++G + V+
Sbjct: 199 MAGGMAGAVSRTGTAPLDRLKVMMQVHGSKGNSNIITGLKQMVKEGGIRSLWRGNGVNVI 258
Query: 740 RDAPAHGLYFWTYEYVRERLHPGCRKSGEETLRTMLVAGGLAGVSSWVVCYPLDVVKTRL 919
+ AP + FW YE ++ +SG+ VAG LAG ++ YP++V+KTRL
Sbjct: 259 KIAPETAMKFWAYEQYKKLF---TSESGKLGTAERFVAGSLAGATAQTSIYPMEVLKTRL 315
Query: 920 QQGNHGSYDGITDCFRKSIAQEGYGVLWRGLGTAVARAFVVNGAIFAAYEVALRCLFPQL 1099
G G Y G+ DC +K + +EG ++G + G A YE L+ + Q
Sbjct: 316 AVGRTGQYSGMFDCAKKIMQKEGIRAFYKGYIPNILGIIPYAGIDLAIYE-TLKNYWLQN 374
Query: 1100 TSADVAN 1120
+ D AN
Sbjct: 375 HAKDSAN 381
>sp|O18757|SCMC1_RABIT Calcium-binding mitochondrial carrier protein SCaMC-1
OS=Oryctolagus cuniculus GN=SLC25A24 PE=1 SV=1
Length = 475
Score = 86 bits (210), Expect = 7e-016
Identities = 50/175 (28%), Positives = 90/175 (51%), Gaps = 5/175 (2%)
Frame = +2
Query: 551 YRGVALGGVGTGAVQSLLLSPVELIKIRLQLQQSNSGPICLA-KTILRREGLKGIYKGLT 727
+R + GG+ GAV +P++ +K+ +Q+ S S I + +++ G++ +++G
Sbjct: 195 WRQLLAGGI-AGAVSRTSTAPLDRLKVMMQVHGSKSMNIFGGFRQMIKEGGVRSLWRGNG 253
Query: 728 ITVLRDAPAHGLYFWTYEYVRERLHPGCRKSGEETLRTMLVAGGLAGVSSWVVCYPLDVV 907
V++ AP + FW YE ++ L +K G ++G +AG ++ YP++V+
Sbjct: 254 TNVIKIAPETAVKFWVYEQYKKLLTEEGQKIG---TFERFISGSMAGATAQTFIYPMEVM 310
Query: 908 KTRLQQGNHGSYDGITDCFRKSIAQEGYGVLWRGLGTAVARAFVVNGAIFAAYEV 1072
KTRL G G Y GI DC +K + EG+G ++G + G A YE+
Sbjct: 311 KTRLAVGKTGQYSGIYDCAKKILKYEGFGAFYKGYVPNLLGIIPYAGIDLAVYEL 365
>sp|Q6KCM7|SCMC2_HUMAN Calcium-binding mitochondrial carrier protein SCaMC-2
OS=Homo sapiens GN=SLC25A25 PE=1 SV=1
Length = 469
Score = 86 bits (210), Expect = 7e-016
Identities = 56/178 (31%), Positives = 90/178 (50%), Gaps = 11/178 (6%)
Frame = +2
Query: 551 YRGVALGGVGTGAVQSLLLSPVELIKIRLQLQQS---NSGPICLAKTILRREGLKGIYKG 721
+R + GG G GAV +P++ +K+ +Q+ S N G + ++R G + +++G
Sbjct: 187 WRHLVAGG-GAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRG 245
Query: 722 LTITVLRDAPAHGLYFWTYEYVRERLHPGCRKSGEETLR--TMLVAGGLAGVSSWVVCYP 895
I VL+ AP + F YE ++ + S +ETLR LVAG LAG + YP
Sbjct: 246 NGINVLKIAPESAIKFMAYEQIKRLV-----GSDQETLRIHERLVAGSLAGAIAQSSIYP 300
Query: 896 LDVVKTRLQQGNHGSYDGITDCFRKSIAQEGYGVLWRGLGTAVARAFVVNGAIFAAYE 1069
++V+KTR+ G Y G+ DC R+ +A+EG ++G + G A YE
Sbjct: 301 MEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYE 358
>sp|Q6NUK1|SCMC1_HUMAN Calcium-binding mitochondrial carrier protein SCaMC-1
OS=Homo sapiens GN=SLC25A24 PE=1 SV=2
Length = 477
Score = 85 bits (209), Expect = 1e-015
Identities = 50/177 (28%), Positives = 90/177 (50%), Gaps = 7/177 (3%)
Frame = +2
Query: 551 YRGVALGGVGTGAVQSLLLSPVELIKIRLQLQQSNSGPICL---AKTILRREGLKGIYKG 721
+R + GG+ GAV +P++ +KI +Q+ S S + + + +++ G++ +++G
Sbjct: 195 WRQLLAGGI-AGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRG 253
Query: 722 LTITVLRDAPAHGLYFWTYEYVRERLHPGCRKSGEETLRTMLVAGGLAGVSSWVVCYPLD 901
V++ AP + FW YE ++ L +K G ++G +AG ++ YP++
Sbjct: 254 NGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIG---TFERFISGSMAGATAQTFIYPME 310
Query: 902 VVKTRLQQGNHGSYDGITDCFRKSIAQEGYGVLWRGLGTAVARAFVVNGAIFAAYEV 1072
V+KTRL G G Y GI DC +K + EG G ++G + G A YE+
Sbjct: 311 VMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYEL 367
>sp|Q7ZY36|SCM1A_XENLA Calcium-binding mitochondrial carrier protein SCaMC-1-A
OS=Xenopus laevis GN=slc25a24-a PE=2 SV=2
Length = 473
Score = 85 bits (208), Expect = 1e-015
Identities = 54/187 (28%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Frame = +2
Query: 566 LGGVGTGAVQSLLLSPVELIKIRLQLQ--QSNSGPICLAKTILRREGLKGIYKGLTITVL 739
L G GAV +P++ +K+ +Q+ + NS I K +++ G++ +++G + V+
Sbjct: 199 LAGGMAGAVSRTGTAPLDRLKVMMQVHGTKGNSNIITGLKQMVKEGGVRSLWRGNGVNVI 258
Query: 740 RDAPAHGLYFWTYEYVRERLHPGCRKSGEETLRTMLVAGGLAGVSSWVVCYPLDVVKTRL 919
+ AP + FW YE ++ +SG+ +AG LAG ++ YP++V+KTRL
Sbjct: 259 KIAPETAMKFWAYEQYKKLF---TSESGKLGTAERFIAGSLAGATAQTSIYPMEVLKTRL 315
Query: 920 QQGNHGSYDGITDCFRKSIAQEGYGVLWRGLGTAVARAFVVNGAIFAAYEVALRCLFPQL 1099
G G Y G+ DC +K + +EG ++G + G A YE L+ + Q
Sbjct: 316 AVGKTGQYSGMFDCAKKIMQKEGILAFYKGYIPNILGIIPYAGIDLAIYE-TLKNYWLQN 374
Query: 1100 TSADVAN 1120
+ D AN
Sbjct: 375 YAKDSAN 381
>sp|A5PJZ1|SCMC1_BOVIN Calcium-binding mitochondrial carrier protein SCaMC-1
OS=Bos taurus GN=SLC25A24 PE=2 SV=1
Length = 477
Score = 84 bits (206), Expect = 2e-015
Identities = 50/177 (28%), Positives = 90/177 (50%), Gaps = 7/177 (3%)
Frame = +2
Query: 551 YRGVALGGVGTGAVQSLLLSPVELIKIRLQLQQSNSGPICL---AKTILRREGLKGIYKG 721
+R + GGV GAV +P++ +K+ +Q+ S S + + + +++ G++ +++G
Sbjct: 195 WRQLLAGGV-AGAVSRTSTAPLDRLKVMMQVHGSKSAKMNIYGGFQQMVKEGGIRSLWRG 253
Query: 722 LTITVLRDAPAHGLYFWTYEYVRERLHPGCRKSGEETLRTMLVAGGLAGVSSWVVCYPLD 901
V++ AP + FW YE ++ L +K G V+G +AG ++ YP++
Sbjct: 254 NGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIG---TFERFVSGSMAGATAQTFIYPME 310
Query: 902 VVKTRLQQGNHGSYDGITDCFRKSIAQEGYGVLWRGLGTAVARAFVVNGAIFAAYEV 1072
V+KTRL G G Y G+ DC +K + EG G ++G + G A YE+
Sbjct: 311 VLKTRLAVGKTGQYSGMFDCAKKILKYEGMGAFYKGYVPNLLGIIPYAGIDLAVYEL 367
>sp|Q7ZYD5|SCMC2_XENLA Calcium-binding mitochondrial carrier protein SCaMC-2
OS=Xenopus laevis GN=slc25a25 PE=2 SV=1
Length = 514
Score = 84 bits (205), Expect = 3e-015
Identities = 53/178 (29%), Positives = 88/178 (49%), Gaps = 11/178 (6%)
Frame = +2
Query: 551 YRGVALGGVGTGAVQSLLLSPVELIKIRLQLQQSNSGPICLA---KTILRREGLKGIYKG 721
+R + GG G GAV +P++ +K+ +Q+ S S + + ++R G + +++G
Sbjct: 232 WRHLVAGG-GAGAVSRTCTAPLDRLKVLMQVHASRSNNMSILGGFTHMIREGGFRSLWRG 290
Query: 722 LTITVLRDAPAHGLYFWTYEYVRERLHPGCRKSGEETL--RTMLVAGGLAGVSSWVVCYP 895
I V++ AP + F YE ++ + S +ETL VAG LAGV + YP
Sbjct: 291 NGINVIKIAPESAIKFMAYEQIKRII-----GSNQETLGIHERFVAGSLAGVIAQSSIYP 345
Query: 896 LDVVKTRLQQGNHGSYDGITDCFRKSIAQEGYGVLWRGLGTAVARAFVVNGAIFAAYE 1069
++V+KTR+ G Y G+ DC +K + QEG ++G + G A YE
Sbjct: 346 MEVLKTRMALRKTGQYQGVLDCGKKILLQEGLSAFYKGYVPNMLGIIPYAGIDLAVYE 403
>sp|A5DIS9|TPC1_PICGU Mitochondrial thiamine pyrophosphate carrier 1 OS=Pichia
guilliermondii GN=TPC1 PE=3 SV=3
Length = 291
Score = 81 bits (199), Expect = 1e-014
Identities = 53/173 (30%), Positives = 87/173 (50%), Gaps = 12/173 (6%)
Frame = +2
Query: 284 VAGGFGGVAGIISGYPLDTLRIRQQQSSKSG--SAFTILRRMLAVEGPASLYRGMAAPLA 457
+ G G+ +I YP D LR R +S+ S +++++ A G A LY G L
Sbjct: 122 IVGTSAGLTSLIVTYPFDLLRTRLAANSERHFLSMTAVIKQVRASGGLAGLYMGAKPTLL 181
Query: 458 SVTFQNAMVFQIYAI---LSRSFDSSLPLEEPPSYRGVALGGVGTGAVQSLLLSPVELIK 628
S+ + ++F Y I +S + ++P E G GA + P++ ++
Sbjct: 182 SLGLNSGLMFWTYEIAREVSAQYKDNIPFIE-------GFCGFFAGASSKGITFPLDTLR 234
Query: 629 IRLQLQQSNSGPICLAKTILRREGLKGIYKGLTITVLRDAPAHGLYFWTYEYV 787
R+Q++ S + I LA+TILRREGL G YKG I++++ AP + + YE V
Sbjct: 235 KRMQMRSSKTSIIGLARTILRREGLFGFYKGFGISLIKTAPTSAVSLFVYEVV 287
>sp|Q8BMD8|SCMC1_MOUSE Calcium-binding mitochondrial carrier protein SCaMC-1
OS=Mus musculus GN=Slc25a24 PE=2 SV=1
Length = 475
Score = 81 bits (198), Expect = 2e-014
Identities = 49/175 (28%), Positives = 88/175 (50%), Gaps = 5/175 (2%)
Frame = +2
Query: 551 YRGVALGGVGTGAVQSLLLSPVELIKIRLQLQQSNSGPICLA-KTILRREGLKGIYKGLT 727
+R + GGV GAV +P++ +K+ +Q+ S S I + +++ G++ +++G
Sbjct: 195 WRQLLAGGV-AGAVSRTSTAPLDRLKVMMQVHGSKSMNIFGGFRQMVKEGGIRSLWRGNG 253
Query: 728 ITVLRDAPAHGLYFWTYEYVRERLHPGCRKSGEETLRTMLVAGGLAGVSSWVVCYPLDVV 907
V++ AP + FW YE ++ L +K G ++G +AG ++ YP++V+
Sbjct: 254 TNVIKIAPETAVKFWAYEQYKKLLTEEGQKLG---TFERFISGSMAGATAQTFIYPMEVL 310
Query: 908 KTRLQQGNHGSYDGITDCFRKSIAQEGYGVLWRGLGTAVARAFVVNGAIFAAYEV 1072
KTRL G Y GI C +K + EG+G ++G + G A YE+
Sbjct: 311 KTRLAVAKTGQYSGIYGCAKKILKHEGFGAFYKGYIPNLLGIIPYAGIDLAVYEL 365
>sp|Q8BW66|MCP62_MOUSE Putative mitochondrial carrier protein FLJ44862 homolog
OS=Mus musculus PE=2 SV=2
Length = 306
Score = 80 bits (197), Expect = 2e-014
Identities = 51/134 (38%), Positives = 71/134 (52%), Gaps = 4/134 (2%)
Frame = +2
Query: 257 MASSWGREFVAGGFGGVAGIISGYPLDTLRIRQQQSSKSGSAFTILRRMLAVEGPASLYR 436
M S +FVAG GGVA +I GYPLDT++ R Q + F +R + E ++
Sbjct: 1 MGSFQLEDFVAGWIGGVASVIVGYPLDTVKTRLQAGVGYANTFNCIRMVYKRERVFGFFK 60
Query: 437 GMAAPLASVTFQNAMVFQIYA----ILSRSFDSSLPLEEPPSYRGVALGGVGTGAVQSLL 604
GM+ PLAS+ N++VF +++ LS+ L S + L + TG V L
Sbjct: 61 GMSFPLASIAIYNSVVFGVFSNTQRFLSKYRCGELEAGPGRSLSDLLLASMLTGVVSVGL 120
Query: 605 LSPVELIKIRLQLQ 646
PVELIKIRLQ+Q
Sbjct: 121 GGPVELIKIRLQMQ 134
>sp|Q9BV35|SCMC3_HUMAN Calcium-binding mitochondrial carrier protein SCaMC-3
OS=Homo sapiens GN=SLC25A23 PE=1 SV=2
Length = 468
Score = 79 bits (194), Expect = 5e-014
Identities = 49/173 (28%), Positives = 86/173 (49%), Gaps = 10/173 (5%)
Frame = +2
Query: 566 LGGVGTGAVQSLLLSPVELIKIRLQLQQSNSGPICL---AKTILRREGLKGIYKGLTITV 736
+ G GAV +P++ +K+ +Q+ S + + + ++++ G++ +++G I V
Sbjct: 190 VAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGINV 249
Query: 737 LRDAPAHGLYFWTYEYVRERLHPGCRKSGEETLRTM--LVAGGLAGVSSWVVCYPLDVVK 910
L+ AP + F YE ++ + +ETL VAG LAG ++ + YP++V+K
Sbjct: 250 LKIAPESAIKFMAYEQIKRAI-----LGQQETLHVQERFVAGSLAGATAQTIIYPMEVLK 304
Query: 911 TRLQQGNHGSYDGITDCFRKSIAQEGYGVLWRGLGTAVARAFVVNGAIFAAYE 1069
TRL G Y G+ DC R+ + +EG +RG V G A YE
Sbjct: 305 TRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYE 357
>sp|Q3MHI3|MCP62_BOVIN Putative mitochondrial carrier protein FLJ44862 homolog
OS=Bos taurus PE=2 SV=1
Length = 311
Score = 77 bits (188), Expect = 3e-013
Identities = 47/128 (36%), Positives = 72/128 (56%), Gaps = 6/128 (4%)
Frame = +2
Query: 278 EFVAGGFGGVAGIISGYPLDTLRIRQQQSSKSGSAFTILRRMLAVEGPASLYRGMAAPLA 457
+FVAG GG A +I G+PLDT++ R Q S GS + +R + E ++GM+ PLA
Sbjct: 8 DFVAGWIGGAASVIVGHPLDTVKARLQAGSGYGSTLSCIRTVYRRESVFGFFKGMSFPLA 67
Query: 458 SVTFQNAMVFQIYAILSRSFDSSLPLEEPPS-----YRGVALGGVGTGAVQSLLLSPVEL 622
S+ N++VF +++ R F S +EP + + L + G V L +PV+L
Sbjct: 68 SIAVYNSVVFGVFSNTQR-FLSHHRCQEPEAGPPHVLSDLLLASMVAGVVSVGLGAPVDL 126
Query: 623 IKIRLQLQ 646
I+IRLQ+Q
Sbjct: 127 IEIRLQMQ 134
>sp|A4QNX2|HDCPB_DANRE Hepatocellular carcinoma down-regulated mitochondrial
carrier homolog B OS=Danio rerio GN=hdmcpb PE=2 SV=1
Length = 288
Score = 75 bits (183), Expect = 1e-012
Identities = 39/125 (31%), Positives = 67/125 (53%), Gaps = 2/125 (1%)
Frame = +2
Query: 278 EFVAGGFGGVAGIISGYPLDTLRIRQQQSSKSGSAFTILRRMLAVEGPASLYRGMAAPLA 457
+F+AG GG G+ GYPLDT+++R Q + + +R+ EG YRGM+ P++
Sbjct: 5 DFLAGSVGGAFGVAVGYPLDTVKVRLQTQTGYSGFWQCVRKTCRNEGLQGFYRGMSMPIS 64
Query: 458 SVTFQNAMVFQIYAILSRSFD--SSLPLEEPPSYRGVALGGVGTGAVQSLLLSPVELIKI 631
+V+ +++VF Y + + EP + L G G Q L+++P +++K+
Sbjct: 65 TVSISSSLVFGTYRNILQFLHQLQHRSAGEPHHKAHIFLAGFTGGVTQVLVMAPADIVKV 124
Query: 632 RLQLQ 646
RLQ Q
Sbjct: 125 RLQCQ 129
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,135,561,348
Number of Sequences: 518415
Number of Extensions: 18135561348
Number of Successful Extensions: 128348820
Number of sequences better than 0.0: 0
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