BLASTX 7.6.2
Query= UN05076 /QuerySize=759
(758 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q32L65|MARH2_BOVIN E3 ubiquitin-protein ligase MARCH2 OS=Bos ... 58 5e-008
sp|Q86UD3|MARH3_HUMAN E3 ubiquitin-protein ligase MARCH3 OS=Homo... 57 9e-008
sp|Q8BRX9|MARH3_MOUSE E3 ubiquitin-protein ligase MARCH3 OS=Mus ... 57 9e-008
sp|Q5XIE5|MARH3_RAT E3 ubiquitin-protein ligase MARCH3 OS=Rattus... 57 9e-008
sp|Q86YJ5|MARH9_HUMAN E3 ubiquitin-protein ligase MARCH9 OS=Homo... 57 9e-008
sp|Q3TZ87|MARH9_MOUSE E3 ubiquitin-protein ligase MARCH9 OS=Mus ... 57 9e-008
sp|A0JN69|MARH3_BOVIN E3 ubiquitin-protein ligase MARCH3 OS=Bos ... 57 2e-007
sp|Q5I0I2|MARH2_RAT E3 ubiquitin-protein ligase MARCH2 OS=Rattus... 56 2e-007
sp|Q80TE3|MARH4_MOUSE E3 ubiquitin-protein ligase MARCH4 OS=Mus ... 55 6e-007
sp|Q0P496|MARH4_DANRE E3 ubiquitin-protein ligase MARCH4 OS=Dani... 54 8e-007
sp|Q99M02|MARH2_MOUSE E3 ubiquitin-protein ligase MARCH2 OS=Mus ... 54 1e-006
sp|Q9P2E8|MARH4_HUMAN E3 ubiquitin-protein ligase MARCH4 OS=Homo... 54 1e-006
sp|Q0IH10|MARH3_XENLA E3 ubiquitin-protein ligase MARCH3 OS=Xeno... 53 2e-006
sp|Q68FA7|MARH3_XENTR E3 ubiquitin-protein ligase MARCH3 OS=Xeno... 53 2e-006
sp|Q5PQ35|MARH2_XENLA E3 ubiquitin-protein ligase MARCH2 OS=Xeno... 51 9e-006
sp|Q28EX7|MARH2_XENTR E3 ubiquitin-protein ligase MARCH2 OS=Xeno... 51 9e-006
>sp|Q32L65|MARH2_BOVIN E3 ubiquitin-protein ligase MARCH2 OS=Bos taurus
GN=MARCH2 PE=2 SV=1
Length = 245
Score = 58 bits (139), Expect = 5e-008
Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 1/100 (1%)
Frame = +1
Query: 199 DCGESSCPQGVRDVASSSSSSSASVDEAEDARKYYAVVAAEEEPLLQSVECRICQEEDIT 378
DC +S V + + + D R V+ A E P CRIC E
Sbjct: 15 DCSDSPAFSKVVEATGLGPPQYVAQVTSRDGRLLSTVIRALETP-SDGPFCRICHEGANG 73
Query: 379 NNLEAPCACNGSLKYAHRKCVQRWCNEKGDIVCEICHQPY 498
+L +PC C+G+L H+ C++RW + CE+CH +
Sbjct: 74 ESLLSPCGCSGTLGAVHKSCLERWLSSSNTSYCELCHTEF 113
>sp|Q86UD3|MARH3_HUMAN E3 ubiquitin-protein ligase MARCH3 OS=Homo sapiens
GN=MARCH3 PE=2 SV=1
Length = 253
Score = 57 bits (137), Expect = 9e-008
Identities = 33/103 (32%), Positives = 47/103 (45%), Gaps = 6/103 (5%)
Frame = +1
Query: 199 DCGESSCP--QGVRDVASSSSSSSASVDE--AEDARKYYAVV--AAEEEPLLQSVECRIC 360
DC S+ P + V D S + V + A+D + VV A + P CRIC
Sbjct: 15 DCTSSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQLLSTVVRTLATQSPFNDRPMCRIC 74
Query: 361 QEEDITNNLEAPCACNGSLKYAHRKCVQRWCNEKGDIVCEICH 489
E +L +PC C G+L HR C++ W + CE+CH
Sbjct: 75 HEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCH 117
>sp|Q8BRX9|MARH3_MOUSE E3 ubiquitin-protein ligase MARCH3 OS=Mus musculus
GN=March3 PE=2 SV=1
Length = 218
Score = 57 bits (137), Expect = 9e-008
Identities = 33/103 (32%), Positives = 47/103 (45%), Gaps = 6/103 (5%)
Frame = +1
Query: 199 DCGESSCP--QGVRDVASSSSSSSASVDE--AEDARKYYAVV--AAEEEPLLQSVECRIC 360
DC S+ P + V D S + V + A+D + VV A + P CRIC
Sbjct: 15 DCTSSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQLLSTVVRTLATQSPFNDRPMCRIC 74
Query: 361 QEEDITNNLEAPCACNGSLKYAHRKCVQRWCNEKGDIVCEICH 489
E +L +PC C G+L HR C++ W + CE+CH
Sbjct: 75 HEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCH 117
>sp|Q5XIE5|MARH3_RAT E3 ubiquitin-protein ligase MARCH3 OS=Rattus norvegicus
GN=March3 PE=1 SV=1
Length = 253
Score = 57 bits (137), Expect = 9e-008
Identities = 33/103 (32%), Positives = 47/103 (45%), Gaps = 6/103 (5%)
Frame = +1
Query: 199 DCGESSCP--QGVRDVASSSSSSSASVDE--AEDARKYYAVV--AAEEEPLLQSVECRIC 360
DC S+ P + V D S + V + A+D + VV A + P CRIC
Sbjct: 15 DCTSSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQLLSTVVRTLATQSPFNDRPMCRIC 74
Query: 361 QEEDITNNLEAPCACNGSLKYAHRKCVQRWCNEKGDIVCEICH 489
E +L +PC C G+L HR C++ W + CE+CH
Sbjct: 75 HEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCH 117
>sp|Q86YJ5|MARH9_HUMAN E3 ubiquitin-protein ligase MARCH9 OS=Homo sapiens
GN=MARCH9 PE=1 SV=2
Length = 346
Score = 57 bits (137), Expect = 9e-008
Identities = 22/56 (39%), Positives = 36/56 (64%)
Frame = +1
Query: 334 LQSVECRICQEEDITNNLEAPCACNGSLKYAHRKCVQRWCNEKGDIVCEICHQPYQ 501
L++ +CRIC + L +PC C+GS++ H+ C+ RW +E+G CE+C+ YQ
Sbjct: 105 LRTPQCRICFQGPEQGELLSPCRCDGSVRCTHQPCLIRWISERGSWSCELCYFKYQ 160
>sp|Q3TZ87|MARH9_MOUSE E3 ubiquitin-protein ligase MARCH9 OS=Mus musculus
GN=March9 PE=2 SV=1
Length = 348
Score = 57 bits (137), Expect = 9e-008
Identities = 22/56 (39%), Positives = 36/56 (64%)
Frame = +1
Query: 334 LQSVECRICQEEDITNNLEAPCACNGSLKYAHRKCVQRWCNEKGDIVCEICHQPYQ 501
L++ +CRIC + L +PC C+GS++ H+ C+ RW +E+G CE+C+ YQ
Sbjct: 105 LRTPQCRICFQGPEQGELLSPCRCDGSVRCTHQPCLIRWISERGSWSCELCYFKYQ 160
>sp|A0JN69|MARH3_BOVIN E3 ubiquitin-protein ligase MARCH3 OS=Bos taurus
GN=MARCH3 PE=2 SV=1
Length = 253
Score = 57 bits (135), Expect = 2e-007
Identities = 33/103 (32%), Positives = 47/103 (45%), Gaps = 6/103 (5%)
Frame = +1
Query: 199 DCGESSCP--QGVRDVASSSSSSSASVDE--AEDARKYYAVV--AAEEEPLLQSVECRIC 360
DC S+ P + V D S + V + A+D + VV A + P CRIC
Sbjct: 15 DCTGSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQLLSTVVRTLATQSPFNDRPMCRIC 74
Query: 361 QEEDITNNLEAPCACNGSLKYAHRKCVQRWCNEKGDIVCEICH 489
E +L +PC C G+L HR C++ W + CE+CH
Sbjct: 75 HEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCH 117
>sp|Q5I0I2|MARH2_RAT E3 ubiquitin-protein ligase MARCH2 OS=Rattus norvegicus
GN=March2 PE=1 SV=1
Length = 246
Score = 56 bits (134), Expect = 2e-007
Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 1/100 (1%)
Frame = +1
Query: 199 DCGESSCPQGVRDVASSSSSSSASVDEAEDARKYYAVVAAEEEPLLQSVECRICQEEDIT 378
DC S V + + + D R V+ A + P CRIC E
Sbjct: 15 DCSSSPAFSKVVEATGLGPPQYVAQVTSRDGRLLSTVIRALDTP-SDCPFCRICHEGANG 73
Query: 379 NNLEAPCACNGSLKYAHRKCVQRWCNEKGDIVCEICHQPY 498
NL +PC C G+L H+ C+++W + CE+CH +
Sbjct: 74 ENLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEF 113
>sp|Q80TE3|MARH4_MOUSE E3 ubiquitin-protein ligase MARCH4 OS=Mus musculus
GN=March4 PE=2 SV=3
Length = 409
Score = 55 bits (130), Expect = 6e-007
Identities = 29/86 (33%), Positives = 49/86 (56%), Gaps = 3/86 (3%)
Frame = +1
Query: 247 SSSSSSASVDE--AEDARKYYAVVAAEEEPLLQSVECRICQEEDITNNLEAPCACNGSLK 420
+S SSAS DE E Y++ ++ + +++ CRIC + L +PC C+GS+K
Sbjct: 127 ASLLSSASSDEFCKEKTEDCYSLGSSLDSG-MRTPLCRICFQGPEQGELLSPCRCDGSVK 185
Query: 421 YAHRKCVQRWCNEKGDIVCEICHQPY 498
H+ C+ +W +E+G CE+C+ Y
Sbjct: 186 CTHQPCLIKWISERGCWSCELCYYKY 211
>sp|Q0P496|MARH4_DANRE E3 ubiquitin-protein ligase MARCH4 OS=Danio rerio
GN=march4 PE=2 SV=1
Length = 421
Score = 54 bits (129), Expect = 8e-007
Identities = 20/51 (39%), Positives = 31/51 (60%)
Frame = +1
Query: 349 CRICQEEDITNNLEAPCACNGSLKYAHRKCVQRWCNEKGDIVCEICHQPYQ 501
CRIC + L +PC C+GS++ H C+ +W +E+G CE+C+ YQ
Sbjct: 143 CRICFQGPEQGELLSPCRCSGSVRCTHEPCLIKWISERGSWSCELCYYKYQ 193
>sp|Q99M02|MARH2_MOUSE E3 ubiquitin-protein ligase MARCH2 OS=Mus musculus
GN=March2 PE=2 SV=1
Length = 246
Score = 54 bits (128), Expect = 1e-006
Identities = 19/50 (38%), Positives = 28/50 (56%)
Frame = +1
Query: 349 CRICQEEDITNNLEAPCACNGSLKYAHRKCVQRWCNEKGDIVCEICHQPY 498
CRIC E NL +PC C G+L H+ C+++W + CE+CH +
Sbjct: 64 CRICHEGANGENLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEF 113
>sp|Q9P2E8|MARH4_HUMAN E3 ubiquitin-protein ligase MARCH4 OS=Homo sapiens
GN=MARCH4 PE=2 SV=2
Length = 410
Score = 54 bits (128), Expect = 1e-006
Identities = 25/85 (29%), Positives = 48/85 (56%)
Frame = +1
Query: 244 SSSSSSSASVDEAEDARKYYAVVAAEEEPLLQSVECRICQEEDITNNLEAPCACNGSLKY 423
+S SS++S D ++ + + + + +++ CRIC + L +PC C+GS+K
Sbjct: 128 ASLLSSASSDDFCKEKTEDRYSLGSSLDSGMRTPLCRICFQGPEQGELLSPCRCDGSVKC 187
Query: 424 AHRKCVQRWCNEKGDIVCEICHQPY 498
H+ C+ +W +E+G CE+C+ Y
Sbjct: 188 THQPCLIKWISERGCWSCELCYYKY 212
>sp|Q0IH10|MARH3_XENLA E3 ubiquitin-protein ligase MARCH3 OS=Xenopus laevis
GN=march3 PE=2 SV=1
Length = 252
Score = 53 bits (126), Expect = 2e-006
Identities = 19/47 (40%), Positives = 26/47 (55%)
Frame = +1
Query: 349 CRICQEEDITNNLEAPCACNGSLKYAHRKCVQRWCNEKGDIVCEICH 489
CRIC E +L +PC C G+L HR C++ W + CE+CH
Sbjct: 70 CRICHEGSTQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCH 116
>sp|Q68FA7|MARH3_XENTR E3 ubiquitin-protein ligase MARCH3 OS=Xenopus tropicalis
GN=march3 PE=2 SV=1
Length = 251
Score = 53 bits (126), Expect = 2e-006
Identities = 19/47 (40%), Positives = 26/47 (55%)
Frame = +1
Query: 349 CRICQEEDITNNLEAPCACNGSLKYAHRKCVQRWCNEKGDIVCEICH 489
CRIC E +L +PC C G+L HR C++ W + CE+CH
Sbjct: 69 CRICHEGSTQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCH 115
>sp|Q5PQ35|MARH2_XENLA E3 ubiquitin-protein ligase MARCH2 OS=Xenopus laevis
GN=march2 PE=2 SV=1
Length = 246
Score = 51 bits (120), Expect = 9e-006
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = +1
Query: 349 CRICQEEDITNNLEAPCACNGSLKYAHRKCVQRWCNEKGDIVCEICHQPY 498
CRIC E L +PC C G+L H+ C+++W + CE+CH +
Sbjct: 64 CRICHEGGNGERLLSPCDCTGTLGTVHKTCLEKWLSSSNTSYCELCHTEF 113
>sp|Q28EX7|MARH2_XENTR E3 ubiquitin-protein ligase MARCH2 OS=Xenopus tropicalis
GN=march2 PE=2 SV=1
Length = 246
Score = 51 bits (120), Expect = 9e-006
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = +1
Query: 349 CRICQEEDITNNLEAPCACNGSLKYAHRKCVQRWCNEKGDIVCEICHQPY 498
CRIC E L +PC C G+L H+ C+++W + CE+CH +
Sbjct: 64 CRICHEGGNGERLLSPCDCTGTLGTVHKTCLEKWLSSSNTSYCELCHTEF 113
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,113,185,847
Number of Sequences: 518415
Number of Extensions: 22113185847
Number of Successful Extensions: 153311817
Number of sequences better than 0.0: 0
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