BLASTX 7.6.2
Query= UN05650 /QuerySize=782
(781 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O48651|ERG1_PANGI Squalene monooxygenase OS=Panax ginseng PE=... 258 5e-068
sp|O65404|ERG11_ARATH Squalene monooxygenase 1,1 OS=Arabidopsis ... 144 6e-034
sp|O65726|ERG12_BRANA Squalene monooxygenase 1,2 OS=Brassica nap... 141 9e-033
sp|O65402|ERG12_ARATH Squalene monooxygenase 1,2 OS=Arabidopsis ... 140 1e-032
sp|O65727|ERG11_BRANA Squalene monooxygenase 1,1 OS=Brassica nap... 125 5e-028
sp|O65403|ERG13_ARATH Squalene monooxygenase 2 OS=Arabidopsis th... 123 2e-027
sp|Q14534|ERG1_HUMAN Squalene monooxygenase OS=Homo sapiens GN=S... 93 2e-018
sp|Q92206|ERG1_CANAL Squalene monooxygenase OS=Candida albicans ... 77 9e-014
sp|P32476|ERG1_YEAST Squalene monooxygenase OS=Saccharomyces cer... 68 5e-011
sp|Q75F69|ERG1_ASHGO Squalene monooxygenase OS=Ashbya gossypii G... 62 5e-009
sp|O13306|ERG1_CANGA Squalene monooxygenase OS=Candida glabrata ... 61 7e-009
>sp|O48651|ERG1_PANGI Squalene monooxygenase OS=Panax ginseng PE=2 SV=1
Length = 539
Score = 258 bits (657), Expect = 5e-068
Identities = 124/156 (79%), Positives = 136/156 (87%)
Frame = -1
Query: 697 LRDLLNPLVDLTDKESLSKYIESFYTLRKPVASTINTLAGALYKVFLASPDDARSEMRRA 518
+RDLL PL DL D +L KY+ESFYTLRKPVASTINTLAGALYKVF ASPD AR EMR A
Sbjct: 384 IRDLLRPLRDLHDSSTLCKYLESFYTLRKPVASTINTLAGALYKVFCASPDKARQEMRNA 443
Query: 517 CFDYLSLGGVCSSGPVALLSGLNPRPMSLVLHFFAVAIFGVGRLLVPLPSVKRLWLGARL 338
CFDYLSLGG+CS GP+ALLSGLNPRP+SL LHFFAVAI+GVGRLL+P PS KR+WLGARL
Sbjct: 444 CFDYLSLGGICSQGPIALLSGLNPRPISLFLHFFAVAIYGVGRLLIPFPSPKRMWLGARL 503
Query: 337 ISSASGIIFPIIKAEGVRQMFFPRTIPAIYRAPPAH 230
I ASGIIFPIIK+EG+RQMFFP +PA YRAPP H
Sbjct: 504 ILGASGIIFPIIKSEGLRQMFFPAIVPAYYRAPPIH 539
Score = 52 bits (123), Expect = 4e-006
Identities = 24/27 (88%), Positives = 25/27 (92%)
Frame = -2
Query: 777 LASGDAFNMRHPLTGGGMTVALSDIVI 697
L GDAFNMRHPLTGGGMTVALSDIV+
Sbjct: 357 LLLGDAFNMRHPLTGGGMTVALSDIVL 383
>sp|O65404|ERG11_ARATH Squalene monooxygenase 1,1 OS=Arabidopsis thaliana
GN=SQP1,1 PE=2 SV=2
Length = 516
Score = 144 bits (363), Expect = 6e-034
Identities = 69/143 (48%), Positives = 98/143 (68%)
Frame = -1
Query: 697 LRDLLNPLVDLTDKESLSKYIESFYTLRKPVASTINTLAGALYKVFLASPDDARSEMRRA 518
LR LL PL +L + + +S+ I+SFY +RKP+++T+NTL A +V +AS D+A+ MR+
Sbjct: 358 LRRLLQPLSNLGNAQKISQVIKSFYDIRKPMSATVNTLGNAFSQVLVASTDEAKEAMRQG 417
Query: 517 CFDYLSLGGVCSSGPVALLSGLNPRPMSLVLHFFAVAIFGVGRLLVPLPSVKRLWLGARL 338
C+DYLS GG +SG +ALL G+NPRP+SL+ H A+ + +G LL P PS R+W RL
Sbjct: 418 CYDYLSSGGFRTSGMMALLGGMNPRPISLIYHLCAITLSSIGHLLSPFPSPLRIWHSLRL 477
Query: 337 ISSASGIIFPIIKAEGVRQMFFP 269
A ++ P +KAEGV QM FP
Sbjct: 478 FGLAMKMLVPHLKAEGVSQMLFP 500
>sp|O65726|ERG12_BRANA Squalene monooxygenase 1,2 OS=Brassica napus GN=SQP1,2
PE=2 SV=1
Length = 518
Score = 141 bits (353), Expect = 9e-033
Identities = 68/151 (45%), Positives = 103/151 (68%), Gaps = 1/151 (0%)
Frame = -1
Query: 697 LRDLLNPLVDLTDKESLSKYIESFYTLRKPVASTINTLAGALYKVFLASPDDARSEMRRA 518
L LL PL +L D+ +S+ ++SFY LRKP+++T+NTL + ++V +AS D+A+ MR+
Sbjct: 360 LSRLLKPLGNLGDENKVSEVMKSFYALRKPMSATVNTLGNSFWQVLIASTDEAKEAMRQG 419
Query: 517 CFDYLSLGGVCSSGPVALLSGLNPRPMSLVLHFFAVAIFGVGRLLVPLPSVKRLWLGARL 338
CFDYLS GG +SG +AL+ G+NPRP+SL H F +++ +G+LL P P+ R+W RL
Sbjct: 420 CFDYLSSGGFRTSGLMALIGGMNPRPLSLFYHLFVISLSSIGQLLSPFPTPLRVWHSLRL 479
Query: 337 ISSASGIIFPIIKAEGVRQMFFPRTIPAIYR 245
+ + ++ P +KAEG+ QM P T A YR
Sbjct: 480 LDLSLKMLVPHLKAEGIGQMLSP-TNAAAYR 509
>sp|O65402|ERG12_ARATH Squalene monooxygenase 1,2 OS=Arabidopsis thaliana
GN=SQP1,2 PE=2 SV=1
Length = 517
Score = 140 bits (351), Expect = 1e-032
Identities = 68/152 (44%), Positives = 98/152 (64%)
Frame = -1
Query: 697 LRDLLNPLVDLTDKESLSKYIESFYTLRKPVASTINTLAGALYKVFLASPDDARSEMRRA 518
LR LL PL +L D +S+ I SFY +RKP+++T+NTL A +V + S D+A+ MR+
Sbjct: 359 LRRLLQPLSNLGDANKVSEVINSFYDIRKPMSATVNTLGNAFSQVLIGSTDEAKEAMRQG 418
Query: 517 CFDYLSLGGVCSSGPVALLSGLNPRPMSLVLHFFAVAIFGVGRLLVPLPSVKRLWLGARL 338
+DYL GG +SG +ALL G+NPRP+SLV H A+ + +G+LL P PS R+W +L
Sbjct: 419 VYDYLCSGGFRTSGMMALLGGMNPRPLSLVYHLCAITLSSIGQLLSPFPSPLRIWHSLKL 478
Query: 337 ISSASGIIFPIIKAEGVRQMFFPRTIPAIYRA 242
A ++ P +KAEGV QM FP A +++
Sbjct: 479 FGLAMKMLVPNLKAEGVSQMLFPANAAAYHKS 510
>sp|O65727|ERG11_BRANA Squalene monooxygenase 1,1 OS=Brassica napus GN=SQP1,1
PE=2 SV=1
Length = 506
Score = 125 bits (312), Expect = 5e-028
Identities = 58/123 (47%), Positives = 84/123 (68%)
Frame = -1
Query: 697 LRDLLNPLVDLTDKESLSKYIESFYTLRKPVASTINTLAGALYKVFLASPDDARSEMRRA 518
LR LL PL +L+D +S+ I+SFY +RKP+++T+NTL A +V +AS D+A+ MR+
Sbjct: 359 LRRLLQPLRNLSDANKVSEVIKSFYVIRKPMSATVNTLGNAFSQVLIASTDEAKEAMRQG 418
Query: 517 CFDYLSLGGVCSSGPVALLSGLNPRPMSLVLHFFAVAIFGVGRLLVPLPSVKRLWLGARL 338
CFDYLS GG +SG +ALL G+NPRP+SL+ H + + +G+LL P PS +W RL
Sbjct: 419 CFDYLSSGGFRTSGMMALLGGMNPRPLSLIFHLCGITLSSIGQLLSPFPSPLGIWHSLRL 478
Query: 337 ISS 329
+
Sbjct: 479 FGA 481
>sp|O65403|ERG13_ARATH Squalene monooxygenase 2 OS=Arabidopsis thaliana GN=SQP2
PE=2 SV=1
Length = 516
Score = 123 bits (307), Expect = 2e-027
Identities = 60/151 (39%), Positives = 98/151 (64%), Gaps = 1/151 (0%)
Frame = -1
Query: 697 LRDLLNPLVDLTDKESLSKYIESFYTLRKPVASTINTLAGALYKVFLASPDDARSEMRRA 518
LR+LL PL +L++ + +S ++SFY +RKP+++T+NTLA +V +A+ D+AR MR+
Sbjct: 358 LRNLLKPLPNLSNTKKVSDLVKSFYIIRKPMSATVNTLASIFSQVLVATTDEAREGMRQG 417
Query: 517 CFDYLSLGGVCSSGPVALLSGLNPRPMSLVLHFFAVAIFGVGRLLVPLPSVKRLWLGARL 338
CF+YL+ G + G + +L G+NP P++LVLH A+ + +G LL P PS +R W R+
Sbjct: 418 CFNYLARGDFKTRGLMTILGGMNPHPLTLVLHLVAITLTSMGHLLSPFPSPRRFWHSLRI 477
Query: 337 ISSASGIIFPIIKAEGVRQMFFPRTIPAIYR 245
++ A ++ + EG ++M P T A YR
Sbjct: 478 LAWALQMLGAHLVDEGFKEMLIP-TNAAAYR 507
>sp|Q14534|ERG1_HUMAN Squalene monooxygenase OS=Homo sapiens GN=SQLE PE=2 SV=3
Length = 574
Score = 93 bits (229), Expect = 2e-018
Identities = 57/138 (41%), Positives = 82/138 (59%), Gaps = 5/138 (3%)
Frame = -1
Query: 694 RDLLNPLVDLTDKESLSKYIESFYTLRKPVAS-TINTLAGALYKVFLASPDDARSEMRRA 518
R LL + DL D ++ + +SFY RK S +N LA ALY++F A+ DD+ ++R+A
Sbjct: 432 RKLLKGIPDLYDDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSAT-DDSLHQLRKA 490
Query: 517 CFDYLSLGGVCSSGPVALLSGLNPRPMSLVLHFFAVAIFGVGRLLVPLPSV---KRLWLG 347
CF Y LGG C +GPV LLS L+P P+ L+ HFFAVAI+ V P + + L
Sbjct: 491 CFLYFKLGGECVAGPVGLLSVLSPNPLVLIGHFFAVAIYAVYFCFKSEPWITKPRALLSS 550
Query: 346 ARLISSASGIIFPIIKAE 293
++ A +IFP+I +E
Sbjct: 551 GAVLYKACSVIFPLIYSE 568
>sp|Q92206|ERG1_CANAL Squalene monooxygenase OS=Candida albicans GN=ERG1 PE=3
SV=1
Length = 496
Score = 77 bits (189), Expect = 9e-014
Identities = 42/103 (40%), Positives = 62/103 (60%), Gaps = 3/103 (2%)
Frame = -1
Query: 697 LRDLLNP--LVDLTDKESLSKYIESFYTLRKPVASTINTLAGALYKVFLASPDDARSEMR 524
L LL+P + D D + ++K +++F+ RK + + INTL+ +LY +F A R +R
Sbjct: 355 LAKLLHPKFVEDFDDHQLIAKRLKTFHRKRKNLDAVINTLSISLYSLFAADKKPLRI-LR 413
Query: 523 RACFDYLSLGGVCSSGPVALLSGLNPRPMSLVLHFFAVAIFGV 395
CF Y GG C +GP+ LLSG+ P PM L HFF+VA + V
Sbjct: 414 NGCFKYFQRGGECVNGPIGLLSGMLPFPMLLFNHFFSVAFYSV 456
>sp|P32476|ERG1_YEAST Squalene monooxygenase OS=Saccharomyces cerevisiae GN=ERG1
PE=1 SV=2
Length = 496
Score = 68 bits (165), Expect = 5e-011
Identities = 34/93 (36%), Positives = 55/93 (59%), Gaps = 1/93 (1%)
Frame = -1
Query: 673 VDLTDKESLSKYIESFYTLRKPVASTINTLAGALYKVFLASPDDARSEMRRACFDYLSLG 494
+D +D+E + + ++ RK S IN L+ ALY +F A D+ ++ +++ CF Y G
Sbjct: 365 LDFSDREKVLDELLDYHFERKSYDSVINVLSVALYSLFAADSDNLKA-LQKGCFKYFQRG 423
Query: 493 GVCSSGPVALLSGLNPRPMSLVLHFFAVAIFGV 395
G C + PV LSG+ P+P+ L FFAVA + +
Sbjct: 424 GDCVNKPVEFLSGVLPKPLQLTRVFFAVAFYTI 456
>sp|Q75F69|ERG1_ASHGO Squalene monooxygenase OS=Ashbya gossypii GN=ERG1 PE=3
SV=1
Length = 497
Score = 62 bits (148), Expect = 5e-009
Identities = 40/127 (31%), Positives = 67/127 (52%), Gaps = 4/127 (3%)
Frame = -1
Query: 673 VDLTDKESLSKYIESFYTLRKPVASTINTLAGALYKVFLASPDDARSEMRRACFDYLSLG 494
+D +D+E + + F+ RK A INTL+ ALY +F A+ ++++ CF+YL G
Sbjct: 366 MDFSDREEVLNELLGFHYERKAHACVINTLSIALYSLF-AADSYYLKKLQKGCFEYLGRG 424
Query: 493 GVCSSGPVALLSGLNPRPMSLVLHFFAVAIFGV---GRLLVPLPSVKRLWLGARLISSAS 323
P++ LSG+ P P L FF VA++ V R PL + ++ G +I +A+
Sbjct: 425 EDWVRQPISFLSGVLPSPYLLTKVFFTVALYSVLINFRGRTPLGFLLAIYEGFAIIFTAA 484
Query: 322 GIIFPII 302
+ P +
Sbjct: 485 KVFTPFL 491
>sp|O13306|ERG1_CANGA Squalene monooxygenase OS=Candida glabrata GN=ERG1 PE=3
SV=2
Length = 489
Score = 61 bits (147), Expect = 7e-009
Identities = 30/93 (32%), Positives = 55/93 (59%), Gaps = 1/93 (1%)
Frame = -1
Query: 673 VDLTDKESLSKYIESFYTLRKPVASTINTLAGALYKVFLASPDDARSEMRRACFDYLSLG 494
+D +D+E + + ++ RK + +N L+ +LY +F A + ++ +++ CF Y G
Sbjct: 358 LDFSDREKVLDELLDYHFERKNYDAVVNVLSISLYSLFAADSKNLKA-LQKGCFKYFQRG 416
Query: 493 GVCSSGPVALLSGLNPRPMSLVLHFFAVAIFGV 395
G C + PVA L+G+ P+P+ L FFAVA + +
Sbjct: 417 GDCVNLPVAFLAGVLPKPLLLTRVFFAVAFYTI 449
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,113,185,847
Number of Sequences: 518415
Number of Extensions: 22113185847
Number of Successful Extensions: 153311817
Number of sequences better than 0.0: 0
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