BLASTX 7.6.2
Query= UN06113 /QuerySize=1165
(1164 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9H8H3|MET7A_HUMAN Methyltransferase-like protein 7A OS=Homo ... 119 6e-026
sp|Q562C4|MET7B_RAT Methyltransferase-like protein 7B OS=Rattus ... 111 1e-023
sp|Q9DD20|MET7B_MOUSE Methyltransferase-like protein 7B OS=Mus m... 107 1e-022
sp|Q6UX53|MET7B_HUMAN Methyltransferase-like protein 7B OS=Homo ... 101 2e-020
sp|A6WYI0|UBIE_OCHA4 Ubiquinone/menaquinone biosynthesis methylt... 57 2e-007
sp|A9MCZ2|UBIE_BRUC2 Ubiquinone/menaquinone biosynthesis methylt... 53 4e-006
sp|Q8FUZ3|UBIE_BRUSU Ubiquinone/menaquinone biosynthesis methylt... 53 4e-006
sp|B2SC50|UBIE_BRUA1 Ubiquinone/menaquinone biosynthesis methylt... 52 6e-006
sp|Q2YJM4|UBIE_BRUA2 Ubiquinone/menaquinone biosynthesis methylt... 52 6e-006
sp|Q576Q0|UBIE_BRUAB Ubiquinone/menaquinone biosynthesis methylt... 52 6e-006
sp|C0RMK3|UBIE_BRUMB Ubiquinone/menaquinone biosynthesis methylt... 52 6e-006
sp|Q8YDE4|UBIE_BRUME Ubiquinone/menaquinone biosynthesis methylt... 52 6e-006
sp|B4RC42|UBIE_PHEZH Ubiquinone/menaquinone biosynthesis methylt... 52 7e-006
>sp|Q9H8H3|MET7A_HUMAN Methyltransferase-like protein 7A OS=Homo sapiens
GN=METTL7A PE=1 SV=1
Length = 244
Score = 119 bits (296), Expect = 6e-026
Identities = 78/201 (38%), Positives = 114/201 (56%), Gaps = 13/201 (6%)
Frame = +2
Query: 347 YEKEIAVYKKKLFANL------VGKAETVLEIGIGAGPNIKYYNNIPNVSVLGVDPNPKM 508
Y +++A K++LF+NL GK ++LE+G G G N K+Y P V +DPNP
Sbjct: 47 YNEQMASKKRELFSNLQEFAGPSGKL-SLLEVGCGTGANFKFYP--PGCRVTCIDPNPNF 103
Query: 509 ESHARKSAIEAGVKSENFKFIHAVAESM-PLEDASVDAVVGSLVMCSVSDIPQTLKEIKR 685
E KS E + +F+ A E+M + D SVD VV +LV+CSV + + L+E+ R
Sbjct: 104 EKFLIKSIAE-NRHLQFERFVVAAGENMHQVADGSVDVVVCTLVLCSVKNQERILREVCR 162
Query: 686 ILKPGGLYLFVEHVAAEDGTFLRMVQNVLDPLQQVVADGCHLTRNTEDYLLEAGFSGGVD 865
+L+PGG + F+EHVAAE T+ Q VLDP ++ DGC+LTR + L A FS +
Sbjct: 163 VLRPGGAFYFMEHVAAECSTWNYFWQQVLDPAWHLLFDGCNLTRESWKALERASFS-KLK 221
Query: 866 INKVSLSAFYHL-SPHLYGVA 925
+ + + L PH+YG A
Sbjct: 222 LQHIQAPLSWELVRPHIYGYA 242
>sp|Q562C4|MET7B_RAT Methyltransferase-like protein 7B OS=Rattus norvegicus
GN=Mettl7b PE=1 SV=1
Length = 244
Score = 111 bits (276), Expect = 1e-023
Identities = 70/186 (37%), Positives = 102/186 (54%), Gaps = 9/186 (4%)
Frame = +2
Query: 314 YGYFRSAGMERYEKEIAVYKKKLFANL-----VGKAETVLEIGIGAGPNIKYYNNIPNVS 478
+ Y + R K++ K++LF+ + T+LE+G G G N ++Y P
Sbjct: 36 FPYLMATLTARSYKKMESKKRELFSQIKDLKGTSNEVTLLELGCGTGANFQFYP--PGCK 93
Query: 479 VLGVDPNPKMESHARKSAIEAGVKSENFKFIHAVAESM-PLEDASVDAVVGSLVMCSVSD 655
V VDPNP E KS E + +FI A E+M L D+S+D VV +LV+CSV
Sbjct: 94 VTCVDPNPNFEKFLTKSMAE-NRHLQYERFIVAYGENMKQLADSSMDVVVCTLVLCSVQS 152
Query: 656 IPQTLKEIKRILKPGGLYLFVEHVAAEDGTFLRMVQNVLDPLQQVVADGCHLTRNTEDYL 835
+ L+E++R+LKPGGL F EHV+ G+ + Q VL+P + + DGCHLTR T +
Sbjct: 153 PRKVLQEVQRVLKPGGLLFFWEHVSEPQGSQALLWQRVLEPTWKHIGDGCHLTRETWKDI 212
Query: 836 LEAGFS 853
+A FS
Sbjct: 213 EKAQFS 218
>sp|Q9DD20|MET7B_MOUSE Methyltransferase-like protein 7B OS=Mus musculus
GN=Mettl7b PE=2 SV=2
Length = 244
Score = 107 bits (267), Expect = 1e-022
Identities = 70/186 (37%), Positives = 101/186 (54%), Gaps = 9/186 (4%)
Frame = +2
Query: 314 YGYFRSAGMERYEKEIAVYKKKLFANLVGKAET-----VLEIGIGAGPNIKYYNNIPNVS 478
+ YF + R K++ K++LF+ + T +LE+G G G N ++Y
Sbjct: 36 FPYFMAMLTARSYKKMESKKRELFSQIKDLKGTSGNVALLELGCGTGANFQFYPQ--GCK 93
Query: 479 VLGVDPNPKMESHARKSAIEAGVKSENFKFIHAVAESM-PLEDASVDAVVGSLVMCSVSD 655
V VDPNP E KS E + +FI A E+M L D+S+D VV +LV+CSV
Sbjct: 94 VTCVDPNPNFEKFLTKSMAE-NRHLQYERFIVAYGENMKQLADSSMDVVVCTLVLCSVQS 152
Query: 656 IPQTLKEIKRILKPGGLYLFVEHVAAEDGTFLRMVQNVLDPLQQVVADGCHLTRNTEDYL 835
+ L+E++R+L+PGGL F EHVA G+ + Q VL+P + + DGCHLTR T +
Sbjct: 153 PRKVLQEVQRVLRPGGLLFFWEHVAEPQGSRAFLWQRVLEPTWKHIGDGCHLTRETWKDI 212
Query: 836 LEAGFS 853
A FS
Sbjct: 213 ERAQFS 218
>sp|Q6UX53|MET7B_HUMAN Methyltransferase-like protein 7B OS=Homo sapiens
GN=METTL7B PE=2 SV=2
Length = 244
Score = 101 bits (249), Expect = 2e-020
Identities = 69/210 (32%), Positives = 106/210 (50%), Gaps = 9/210 (4%)
Frame = +2
Query: 314 YGYFRSAGMERYEKEIAVYKKKLFANLVGKA-----ETVLEIGIGAGPNIKYYNNIPNVS 478
+ Y + + +++ K++LF+ + G +LE+G G G N ++Y P
Sbjct: 36 FPYLMAVLTPKSNRKMESKKRELFSQIKGLTGASGKVALLELGCGTGANFQFYP--PGCR 93
Query: 479 VLGVDPNPKMESHARKSAIEAGVKSENFKFIHAVAESM-PLEDASVDAVVGSLVMCSVSD 655
V +DPNP E KS E + +F+ A E M L D S+D VV +LV+CSV
Sbjct: 94 VTCLDPNPHFEKFLTKSMAE-NRHLQYERFVVAPGEDMRQLADGSMDVVVCTLVLCSVQS 152
Query: 656 IPQTLKEIKRILKPGGLYLFVEHVAAEDGTFLRMVQNVLDPLQQVVADGCHLTRNTEDYL 835
+ L+E++R+L+PGG+ F EHVA G++ M Q V +P + + DGC LTR T L
Sbjct: 153 PRKVLQEVRRVLRPGGVLFFWEHVAEPYGSWAFMWQQVFEPTWKHIGDGCCLTRETWKDL 212
Query: 836 LEAGFSGGVDINKVSLSAFYHLSPHLYGVA 925
A FS + + + PH+ G A
Sbjct: 213 ENAQFSEIQMERQPPPLKWLPVGPHIMGKA 242
>sp|A6WYI0|UBIE_OCHA4 Ubiquinone/menaquinone biosynthesis methyltransferase ubiE
OS=Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168)
GN=ubiE PE=3 SV=1
Length = 263
Score = 57 bits (137), Expect = 2e-007
Identities = 48/151 (31%), Positives = 74/151 (49%), Gaps = 16/151 (10%)
Frame = +2
Query: 305 FELYGYFRSAGMERYEKEIAVYKKKLFANLVGKAE---TVLEIGIGAGP----NIKYYNN 463
+++ SAGM R V+K + A L T L++ G G ++
Sbjct: 46 YDVMNDLMSAGMHR------VWKDAMIAWLAPSKRPGWTSLDVAGGTGDIAFRIVEASGR 99
Query: 464 IPNVSVLGVDPNPKMESHARKSAIEAGVKSENFKFIHAVAESMPLEDASVDAVVGSLVMC 643
+V++L D N M R+ AI+ G+ ++N +F+ A AE +P EDAS DA S +
Sbjct: 100 QAHVTIL--DINGSMLGVGRERAIKKGL-ADNLEFVEASAEELPFEDASFDAYTISFGIR 156
Query: 644 SVSDIPQTLKEIKRILKPGGLYLFVEHVAAE 736
+V I + L E R+LKPGG +L +E E
Sbjct: 157 NVPHIDKALSEAYRVLKPGGRFLCLEFSEVE 187
>sp|A9MCZ2|UBIE_BRUC2 Ubiquinone/menaquinone biosynthesis methyltransferase ubiE
OS=Brucella canis (strain ATCC 23365 / NCTC 10854) GN=ubiE PE=3 SV=1
Length = 269
Score = 53 bits (125), Expect = 4e-006
Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 10/148 (6%)
Frame = +2
Query: 305 FELYGYFRSAGMERYEKEIAVYKKKLFANLVGKAETVLEIGIGAGP----NIKYYNNIPN 472
+++ SAGM R K+ V A T L++ G G ++ +
Sbjct: 52 YDIMNDLMSAGMHRVWKDAMV---AWLAPSKRPGWTSLDVAGGTGDIAFRIVEVSGRQAH 108
Query: 473 VSVLGVDPNPKMESHARKSAIEAGVKSENFKFIHAVAESMPLEDASVDAVVGSLVMCSVS 652
V++L D N M R+ AI+ G+ +N +F+ A AE +P ED S DA + + +V
Sbjct: 109 VTIL--DINGSMLGVGRERAIKKGL-IDNLEFVEANAEELPFEDNSFDAYTIAFGIRNVP 165
Query: 653 DIPQTLKEIKRILKPGGLYLFVEHVAAE 736
I + L E R+LKPGG +L +E E
Sbjct: 166 HIDKALSEAYRVLKPGGRFLCLEFSEVE 193
>sp|Q8FUZ3|UBIE_BRUSU Ubiquinone/menaquinone biosynthesis methyltransferase ubiE
OS=Brucella suis GN=ubiE PE=3 SV=1
Length = 269
Score = 53 bits (125), Expect = 4e-006
Identities = 46/151 (30%), Positives = 72/151 (47%), Gaps = 16/151 (10%)
Frame = +2
Query: 305 FELYGYFRSAGMERYEKEIAVYKKKLFANLVGKAE---TVLEIGIGAGP----NIKYYNN 463
+++ SAGM R V+K + A L T L++ G G ++
Sbjct: 52 YDIMNDLMSAGMHR------VWKDAMVAWLTPSKRPGWTSLDVAGGTGDIAFRIVEVSGR 105
Query: 464 IPNVSVLGVDPNPKMESHARKSAIEAGVKSENFKFIHAVAESMPLEDASVDAVVGSLVMC 643
+V++L D N M R+ AI+ G+ +N +F+ A AE +P ED S DA + +
Sbjct: 106 QAHVTIL--DINGSMLGVGRERAIKKGL-IDNLEFVEANAEELPFEDNSFDAYTIAFGIR 162
Query: 644 SVSDIPQTLKEIKRILKPGGLYLFVEHVAAE 736
+V I + L E R+LKPGG +L +E E
Sbjct: 163 NVPHIDKALSEAYRVLKPGGRFLCLEFSEVE 193
>sp|B2SC50|UBIE_BRUA1 Ubiquinone/menaquinone biosynthesis methyltransferase ubiE
OS=Brucella abortus (strain S19) GN=ubiE PE=3 SV=1
Length = 269
Score = 52 bits (124), Expect = 6e-006
Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 10/148 (6%)
Frame = +2
Query: 305 FELYGYFRSAGMERYEKEIAVYKKKLFANLVGKAETVLEIGIGAGP----NIKYYNNIPN 472
+++ SAGM R K+ V A T L++ G G ++ +
Sbjct: 52 YDIMNDLMSAGMHRVWKDAMV---AWLAPSKRPGWTSLDVAGGTGDIAFRIVEASGRQAH 108
Query: 473 VSVLGVDPNPKMESHARKSAIEAGVKSENFKFIHAVAESMPLEDASVDAVVGSLVMCSVS 652
V++L D N M R+ AI+ G+ +N +F+ A AE +P ED S DA + + +V
Sbjct: 109 VTIL--DINGSMLGVGRERAIKKGL-IDNLEFVEANAEELPFEDNSFDAYTIAFGIRNVP 165
Query: 653 DIPQTLKEIKRILKPGGLYLFVEHVAAE 736
I + L E R+LKPGG +L +E E
Sbjct: 166 HIDKALSEAYRVLKPGGRFLCLEFSEVE 193
>sp|Q2YJM4|UBIE_BRUA2 Ubiquinone/menaquinone biosynthesis methyltransferase ubiE
OS=Brucella abortus (strain 2308) GN=ubiE PE=3 SV=1
Length = 269
Score = 52 bits (124), Expect = 6e-006
Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 10/148 (6%)
Frame = +2
Query: 305 FELYGYFRSAGMERYEKEIAVYKKKLFANLVGKAETVLEIGIGAGP----NIKYYNNIPN 472
+++ SAGM R K+ V A T L++ G G ++ +
Sbjct: 52 YDIMNDLMSAGMHRVWKDAMV---AWLAPSKRPGWTSLDVAGGTGDIAFRIVEASGRQAH 108
Query: 473 VSVLGVDPNPKMESHARKSAIEAGVKSENFKFIHAVAESMPLEDASVDAVVGSLVMCSVS 652
V++L D N M R+ AI+ G+ +N +F+ A AE +P ED S DA + + +V
Sbjct: 109 VTIL--DINGSMLGVGRERAIKKGL-IDNLEFVEANAEELPFEDNSFDAYTIAFGIRNVP 165
Query: 653 DIPQTLKEIKRILKPGGLYLFVEHVAAE 736
I + L E R+LKPGG +L +E E
Sbjct: 166 HIDKALSEAYRVLKPGGRFLCLEFSEVE 193
>sp|Q576Q0|UBIE_BRUAB Ubiquinone/menaquinone biosynthesis methyltransferase ubiE
OS=Brucella abortus GN=ubiE PE=3 SV=1
Length = 269
Score = 52 bits (124), Expect = 6e-006
Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 10/148 (6%)
Frame = +2
Query: 305 FELYGYFRSAGMERYEKEIAVYKKKLFANLVGKAETVLEIGIGAGP----NIKYYNNIPN 472
+++ SAGM R K+ V A T L++ G G ++ +
Sbjct: 52 YDIMNDLMSAGMHRVWKDAMV---AWLAPSKRPGWTSLDVAGGTGDIAFRIVEASGRQAH 108
Query: 473 VSVLGVDPNPKMESHARKSAIEAGVKSENFKFIHAVAESMPLEDASVDAVVGSLVMCSVS 652
V++L D N M R+ AI+ G+ +N +F+ A AE +P ED S DA + + +V
Sbjct: 109 VTIL--DINGSMLGVGRERAIKKGL-IDNLEFVEANAEELPFEDNSFDAYTIAFGIRNVP 165
Query: 653 DIPQTLKEIKRILKPGGLYLFVEHVAAE 736
I + L E R+LKPGG +L +E E
Sbjct: 166 HIDKALSEAYRVLKPGGRFLCLEFSEVE 193
>sp|C0RMK3|UBIE_BRUMB Ubiquinone/menaquinone biosynthesis methyltransferase ubiE
OS=Brucella melitensis biotype 2 (strain ATCC 23457) GN=ubiE PE=3 SV=1
Length = 269
Score = 52 bits (124), Expect = 6e-006
Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 10/148 (6%)
Frame = +2
Query: 305 FELYGYFRSAGMERYEKEIAVYKKKLFANLVGKAETVLEIGIGAGP----NIKYYNNIPN 472
+++ SAGM R K+ V A T L++ G G ++ +
Sbjct: 52 YDIMNDLMSAGMHRVWKDAMV---AWLAPSKRPGWTSLDVAGGTGDIAFRIVEASGRQAH 108
Query: 473 VSVLGVDPNPKMESHARKSAIEAGVKSENFKFIHAVAESMPLEDASVDAVVGSLVMCSVS 652
V++L D N M R+ AI+ G+ +N +F+ A AE +P ED S DA + + +V
Sbjct: 109 VTIL--DINGSMLGVGRERAIKKGL-IDNLEFVEANAEELPFEDNSFDAYTIAFGIRNVP 165
Query: 653 DIPQTLKEIKRILKPGGLYLFVEHVAAE 736
I + L E R+LKPGG +L +E E
Sbjct: 166 HIDKALSEAYRVLKPGGRFLCLEFSEVE 193
>sp|Q8YDE4|UBIE_BRUME Ubiquinone/menaquinone biosynthesis methyltransferase ubiE
OS=Brucella melitensis GN=ubiE PE=3 SV=1
Length = 269
Score = 52 bits (124), Expect = 6e-006
Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 10/148 (6%)
Frame = +2
Query: 305 FELYGYFRSAGMERYEKEIAVYKKKLFANLVGKAETVLEIGIGAGP----NIKYYNNIPN 472
+++ SAGM R K+ V A T L++ G G ++ +
Sbjct: 52 YDIMNDLMSAGMHRVWKDAMV---AWLAPSKRPGWTSLDVAGGTGDIAFRIVEASGRQAH 108
Query: 473 VSVLGVDPNPKMESHARKSAIEAGVKSENFKFIHAVAESMPLEDASVDAVVGSLVMCSVS 652
V++L D N M R+ AI+ G+ +N +F+ A AE +P ED S DA + + +V
Sbjct: 109 VTIL--DINGSMLGVGRERAIKKGL-IDNLEFVEANAEELPFEDNSFDAYTIAFGIRNVP 165
Query: 653 DIPQTLKEIKRILKPGGLYLFVEHVAAE 736
I + L E R+LKPGG +L +E E
Sbjct: 166 HIDKALSEAYRVLKPGGRFLCLEFSEVE 193
>sp|B4RC42|UBIE_PHEZH Ubiquinone/menaquinone biosynthesis methyltransferase ubiE
OS=Phenylobacterium zucineum (strain HLK1) GN=ubiE PE=3 SV=1
Length = 252
Score = 52 bits (123), Expect = 7e-006
Identities = 42/150 (28%), Positives = 72/150 (48%), Gaps = 22/150 (14%)
Frame = +2
Query: 305 FELYGYFRSAGMERYEKEIAVYKKKLFANLVGK-AETVLEIGIGAGPNIKYYNNI----- 466
++L SAG+ R ++K + A L + ET+L++ G G + + +
Sbjct: 33 YDLMNDLMSAGVHR------LWKDAVAARLNPQPGETILDVAGGTGDMARRFARMARRAQ 86
Query: 467 -----PNVSVLGVDPNPKMESHARKSAIEAGVKSENFKFIHAVAESMPLEDASVDAVVGS 631
+ V +D N +M + R+ E + + A+ +PL DA DA V S
Sbjct: 87 ERRGGDDAKVFVIDYNAEMIAAGRERGFEPEI-----CWTVGDAQRLPLPDACADAYVIS 141
Query: 632 LVMCSVSDIPQTLKEIKRILKPGGLYLFVE 721
+ +V+DIP L+E +R+LKPGG +L +E
Sbjct: 142 FGIRNVTDIPAALREARRVLKPGGRFLCLE 171
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,099,029,888
Number of Sequences: 518415
Number of Extensions: 26099029888
Number of Successful Extensions: 175876120
Number of sequences better than 0.0: 0
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