BLASTX 7.6.2
Query= UN06186 /QuerySize=1203
(1202 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O75400|PR40A_HUMAN Pre-mRNA-processing factor 40 homolog A OS... 121 1e-026
sp|Q9R1C7|PR40A_MOUSE Pre-mRNA-processing factor 40 homolog A OS... 119 4e-026
sp|P34600|YO61_CAEEL WW domain-containing protein ZK1098.1 OS=Ca... 96 5e-019
sp|Q568R1|CCD55_DANRE Coiled-coil domain-containing protein 55 O... 56 4e-007
sp|Q6P7Y3|PR38B_DANRE Pre-mRNA-splicing factor 38B OS=Danio reri... 54 2e-006
>sp|O75400|PR40A_HUMAN Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens
GN=PRPF40A PE=1 SV=2
Length = 957
Score = 121 bits (302), Expect = 1e-026
Identities = 90/335 (26%), Positives = 154/335 (45%), Gaps = 22/335 (6%)
Frame = +3
Query: 9 KKAERKHRDEFRGLIDEHIATGDLTAKTSWRDYLMKVKDLPVYLAIASNSTGATPKDLFE 188
++ +RK+R+ F+ +DE G L + +SW + + + G+T DLF+
Sbjct: 604 RRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISS-DIRFTNMLGQPGSTALDLFK 662
Query: 189 DAVEDLKRKYHELKSQIKDVFKVRKVTLSAGSTFGEFKVSVSEGIGFPSIPDVKLKLVFD 368
VEDLK +YH+ K IKD+ K + + +TF +F +S ++ +KL F+
Sbjct: 663 FYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFN 722
Query: 369 DLLERA----KEKEEKEARKQTRNTEKLVDMLR-SFKYITASSSWEDSKHLVEGSEKFRS 533
LLE+A +E+E++EARK R ML+ + I + WED + F
Sbjct: 723 SLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFED 782
Query: 534 IGDESFRKKTFEDYLSHLKEQAKRIKQNKKEHVREEHYKGNDKYGREKDRVRERDSRDHR 713
I ES RK+ F+D++ L EH + H+ N K+ ++ + + SR
Sbjct: 783 ITLESERKRIFKDFMHVL------------EHECQHHHSKNKKHSKKSKKHHRKRSRSRS 830
Query: 714 KQGSADNHNHNVDELRGKEGRRSGRDSHSRHGER-HTSVKEIETDHYKESHKAGGGHKKS 890
S D+ +H+ + + E R + S S ER + K+ + K HK+ +
Sbjct: 831 GSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDA 890
Query: 891 RQERGFVLEAEDEGREKRRRKEGESEQHTKGAEKK 995
+E+ E + E + R R+ ES+ K +KK
Sbjct: 891 EREKD-KKEKDRESEKDRTRQRSESKH--KSPKKK 922
>sp|Q9R1C7|PR40A_MOUSE Pre-mRNA-processing factor 40 homolog A OS=Mus musculus
GN=Prpf40a PE=1 SV=1
Length = 953
Score = 119 bits (298), Expect = 4e-026
Identities = 86/340 (25%), Positives = 152/340 (44%), Gaps = 19/340 (5%)
Frame = +3
Query: 9 KKAERKHRDEFRGLIDEHIATGDLTAKTSWRDYLMKVKDLPVYLAIASNSTGATPKDLFE 188
++ +RK+R+ F+ +DE G L + +SW + + + G+T DLF+
Sbjct: 600 RRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISS-DIRFTNMLGQPGSTALDLFK 658
Query: 189 DAVEDLKRKYHELKSQIKDVFKVRKVTLSAGSTFGEFKVSVSEGIGFPSIPDVKLKLVFD 368
VEDLK +YH+ K IKD+ K + + +TF +F +S ++ +KL F+
Sbjct: 659 FYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFN 718
Query: 369 DLLERA----KEKEEKEARKQTRNTEKLVDMLR-SFKYITASSSWEDSKHLVEGSEKFRS 533
LLE+A +E+E++EARK R ML+ + I + WED + F
Sbjct: 719 SLLEKAEAREREREKEEARKMKRKESAFKSMLKQATPPIELDAVWEDIRERFVKEPAFED 778
Query: 534 IGDESFRKKTFEDYLSHLKEQAKRIKQNKKEHVREEHYKGNDKYGREKDRVRERDSRDHR 713
I ES RK+ F+D++ L EH + H+ N K+ ++ + + SR
Sbjct: 779 ITLESERKRIFKDFMHVL------------EHECQHHHSKNKKHSKKSKKHHRKRSRSRS 826
Query: 714 KQGSADNHNHNVDELRGKEGRRSGRDSHSRHGER-HTSVKEIETDHYKESHKAGGGHKKS 890
S D+ +H+ + + E + S S ER + K+ + K HK+ +
Sbjct: 827 GSESDDDDSHSKKKRQRSESHSASERSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDT 886
Query: 891 RQERGFVLEAEDEGREKRRRKEGESEQHTKGAEKKRSLRW 1010
+E+ + D +++ R++ + K K S W
Sbjct: 887 EREKDKKEKDRDSEKDRSRQRSESKHKSPKKKTGKDSGNW 926
>sp|P34600|YO61_CAEEL WW domain-containing protein ZK1098.1 OS=Caenorhabditis
elegans GN=ZK1098.1 PE=4 SV=2
Length = 724
Score = 96 bits (237), Expect = 5e-019
Identities = 71/282 (25%), Positives = 136/282 (48%), Gaps = 11/282 (3%)
Frame = +3
Query: 6 IKKAERKHRDEFRGLIDEHIATGDLTAKTSWRDYLMKVKDLPVYLAIASNSTGATPKDLF 185
+++ +RK R+E+R L++ G+LT+ + W L + + G++P DLF
Sbjct: 438 LRRQQRKVREEYRLLLESLHKRGELTSMSLWTS-LFPIISTDTRFELMLFQPGSSPLDLF 496
Query: 186 EDAVEDLKRKYHELKSQIKDVFKVRKVTLSAGSTFGEFKVSVSEGIGFPSIPDVKLKLVF 365
+ VEDLK +Y E + IK++ + + A + + EF V + +KL +
Sbjct: 497 KFFVEDLKEQYTEDRRLIKEILTEKGCQVIATTEYREFSDWVVSHEKGGKVDHGNMKLCY 556
Query: 366 DDLLERAKEK---EEKEARKQTRNTEKLVDMLRSFKYITASSSWEDSKHLVEGSEKFRSI 536
+ L+E+A+ K EEKE+ ++ R E L + S W K +E + + ++
Sbjct: 557 NSLIEKAESKAKDEEKESLRRKRRLESEFRNLLKEHNVDKDSEWTVIKPKIEKDKAYLAM 616
Query: 537 GDESFRKKTFEDY---LSHLKEQAKRIKQNKKEHVREEHYKGNDKYGREKDRVRERDSRD 707
++ R+ F Y S ++ +++ KK+ +++ K +D + +RE++ +
Sbjct: 617 ENDDERETAFNHYKNGTSGTTAGSEILEKKKKKKDKKKKNKRSDNNSESEGEIREKEKKK 676
Query: 708 HRKQGSADNHNHNVDELRGKEGRRSGRDSHSR-HGERHTSVK 830
+K D + DE RGK+ ++S + S SR RH+S K
Sbjct: 677 KKKHSKEDRMD---DEERGKKSKKSRKRSPSRSESPRHSSEK 715
>sp|Q568R1|CCD55_DANRE Coiled-coil domain-containing protein 55 OS=Danio rerio
GN=ccdc55 PE=1 SV=2
Length = 516
Score = 56 bits (134), Expect = 4e-007
Identities = 79/364 (21%), Positives = 144/364 (39%), Gaps = 66/364 (18%)
Frame = +3
Query: 3 EIKKAERKHRDEFRGLIDEHIATGDLTAKTSWRDYLMKVKDLPVYLAIASNSTGATPKDL 182
E +K E++ RDE R + E A G+ K D ++ A +
Sbjct: 110 EERKKEQERRDE-RKIQKEREAEGE------------KFADKEAFVTSAY-------RQK 149
Query: 183 FEDAVEDLKRKYHELKSQIK-DVFKVRKVTLSAGSTFGEFKVSVSEGIGFPSIPD----V 347
++ E+L+R+ E + + DV K + ++ G ++ +++ +G +PD
Sbjct: 150 LKERQEELEREKREAELEAALDVKKQKDLS-------GFYRHFLNQTVGEEVVPDRSAQS 202
Query: 348 KLKLVFDDLLERAKEKE----EKEARKQTRNTEKLVDMLRSFKYITASS----SWEDSKH 503
+ K ER+ E +E+ ++ + + VD+ +F TA++ +
Sbjct: 203 EEKATSSAAAERSPSPESTANRRESEAESHSDDDQVDVKPAFSKTTANNHAKRQYRQKSP 262
Query: 504 LVEGSEKFRSIGDESFRKKTFEDYLSHLKEQAKRIKQNKKEHVREEHYKGNDKYGREKDR 683
L + + GDE R++ SH R K+ ++E +R++ + K R DR
Sbjct: 263 LSDSDD-----GDERERERKEIKEKSHKDRDRDRAKEKERERMRDKDKHSHRKEDRGGDR 317
Query: 684 VRERDSRDHRKQGSAD---NHNHNVDELRGKEGRRSGRDSHSRHGERHTSVKEIETDHYK 854
RERD + R + D N H + + R + RD R S K+ E D
Sbjct: 318 RRERDREEDRARDRRDRDRNDRHGIRDRRNSSPKDRERDRKGERDRRDNSPKDRERDRKG 377
Query: 855 ESHKAGGGHK-----------KSRQERGFVLEAEDEGREKRRRKEGESEQHTKGAEKKRS 1001
E + K K R+++ +D RE+R + + E KG +R
Sbjct: 378 ERDRRDNSPKDRERETRDKSPKDRRDK----SPKDRDRERRDKSPKDREPERKG---ERD 430
Query: 1002 LRWR 1013
+R R
Sbjct: 431 IRER 434
>sp|Q6P7Y3|PR38B_DANRE Pre-mRNA-splicing factor 38B OS=Danio rerio GN=prpf38b
PE=2 SV=1
Length = 501
Score = 54 bits (129), Expect = 2e-006
Identities = 43/134 (32%), Positives = 67/134 (50%), Gaps = 8/134 (5%)
Frame = +3
Query: 612 QNKKEHVREEHYKGNDKYGREKDRVRERD---SRDHRKQGSADNHNHNVDELRGKEGRRS 782
+ +++ R+E +G D+ R++DR RERD RD R+ + D N R +E RRS
Sbjct: 283 ERERDRQRKER-EGKDR-DRDRDRDRERDRERDRDRRRSRTPD-RNAERRRSRSRERRRS 339
Query: 783 GRDSHSRHGERHTSVKEIETDHYKE-SHKAGGGHKKSRQERGFVLEAEDEGREKRRRKEG 959
S + ER K+ E + +E S K H K R ER ++ EG E+R + +
Sbjct: 340 RSTSRDKRTERKDRDKDREAESERERSRKKDREHHKDR-ERSKDKRSKGEGEERRHKDDK 398
Query: 960 ESEQHTKGAEKKRS 1001
E ++H + KRS
Sbjct: 399 EEKKHREEKRSKRS 412
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,099,029,888
Number of Sequences: 518415
Number of Extensions: 26099029888
Number of Successful Extensions: 175876120
Number of sequences better than 0.0: 0
|
