BLASTX 7.6.2
Query= UN06460 /QuerySize=1062
(1061 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q20390|PPT1_CAEEL Palmitoyl-protein thioesterase 1 OS=Caenorh... 119 4e-026
sp|P45478|PPT1_BOVIN Palmitoyl-protein thioesterase 1 OS=Bos tau... 107 1e-022
sp|P50897|PPT1_HUMAN Palmitoyl-protein thioesterase 1 OS=Homo sa... 106 3e-022
sp|Q8HXW6|PPT1_MACFA Palmitoyl-protein thioesterase 1 OS=Macaca ... 106 3e-022
sp|Q54CM0|PPT3_DICDI Palmitoyl-protein thioesterase 3 OS=Dictyos... 102 5e-021
sp|O88531|PPT1_MOUSE Palmitoyl-protein thioesterase 1 OS=Mus mus... 101 1e-020
sp|O59747|PDF1_SCHPO Palmitoyl-protein thioesterase-dolichyl pyr... 93 3e-018
sp|Q6GNY7|PPT2B_XENLA Lysosomal thioesterase PPT2-B OS=Xenopus l... 65 7e-010
>sp|Q20390|PPT1_CAEEL Palmitoyl-protein thioesterase 1 OS=Caenorhabditis elegans
GN=ppt-1 PE=2 SV=2
Length = 298
Score = 119 bits (297), Expect = 4e-026
Identities = 76/245 (31%), Positives = 122/245 (49%), Gaps = 13/245 (5%)
Frame = +3
Query: 66 VLLLMVAAVLFSTVPVSNSIPFILFHGIGDKCSGGVS--NFTQLL-SNLSGSPGSCLEIG 236
+LL ++A + +P +++HG+GD C +S + +L + G L++G
Sbjct: 6 LLLCLLAITTAEFRNATKQVPVVMWHGMGDCCCNPLSMGSVKKLFEEQIPGVYVHSLQLG 65
Query: 237 NGET----DSWFMPLTQQTSLACEKVKMMKELSQGYNIVAQSQGNLVARGIIEFCDDAPP 404
+ T ++ + +AC K+K EL GYN + SQG R + + C + PP
Sbjct: 66 SSITKDIEHGFYANTNELVYMACIKIKNDPELKNGYNAIGFSQGAQFLRAVAQRCPN-PP 124
Query: 405 LINYVSLGGPHAGIAAIPKC-SSGPFCAIAEALMKLEIYNDFVQDHIAPSGYVKIPGEMT 581
+ N VS+GG H G+ P C C L+ L Y FVQ + + Y P ++
Sbjct: 125 MKNLVSVGGQHQGVFGAPYCIGDNIMCNGVRRLIDLGAYLPFVQKRVVQAQYWHDPNQVE 184
Query: 582 KYLGHSKYLPKLNNERPDQRNSTFKDRFVSLHNLVLVM--NDTTLIPKETSWFGYYSDDG 755
+Y S +L +NNE + N T+K +SL NLVLV D ++PK++SWFG+Y D
Sbjct: 185 EYKKRSIFLADINNE--NNNNPTYKRNLLSLKNLVLVKFNQDHMVVPKDSSWFGFYKDGD 242
Query: 756 FDSLL 770
D++L
Sbjct: 243 IDTIL 247
>sp|P45478|PPT1_BOVIN Palmitoyl-protein thioesterase 1 OS=Bos taurus GN=PPT1
PE=1 SV=1
Length = 306
Score = 107 bits (267), Expect = 1e-022
Identities = 63/218 (28%), Positives = 107/218 (49%), Gaps = 14/218 (6%)
Frame = +3
Query: 123 IPFILFHGIGDKCSGGVSNFT---QLLSNLSGSPGSCLEIG----NGETDSWFMPLTQQT 281
+P +++HG+GD C +S + + G LEIG +S+F+ + Q
Sbjct: 33 LPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIHVLSLEIGKTLREDVENSFFLNVNSQV 92
Query: 282 SLACEKVKMMKELSQGYNIVAQSQGNLVARGIIEFCDDAPPLINYVSLGGPHAGIAAIPK 461
+ C+ + +L QGYN + SQG R + + C +PP++N +S+GG H G+ +P+
Sbjct: 93 TTVCQILAKDPKLQQGYNAMGFSQGGQFLRAVAQRC-PSPPMVNLISVGGQHQGVFGLPR 151
Query: 462 C--SSGPFCAIAEALMKLEIYNDFVQDHIAPSGYVKIPGEMTKYLGHSKYLPKLNNERPD 635
C S C + YN +Q+ + + Y P Y HS +L +N ER
Sbjct: 152 CPGESSHICDFIRKTLNAGAYNKAIQERLVQAEYWHDPIREDIYRNHSIFLADINQER-- 209
Query: 636 QRNSTFKDRFVSLHNLVLV--MNDTTLIPKETSWFGYY 743
N ++K ++L V+V +NDT + P ++ WFG+Y
Sbjct: 210 GVNESYKKNLMALKKFVMVKFLNDTIVDPVDSEWFGFY 247
>sp|P50897|PPT1_HUMAN Palmitoyl-protein thioesterase 1 OS=Homo sapiens GN=PPT1
PE=1 SV=1
Length = 306
Score = 106 bits (264), Expect = 3e-022
Identities = 63/218 (28%), Positives = 108/218 (49%), Gaps = 14/218 (6%)
Frame = +3
Query: 123 IPFILFHGIGDKCSGGVSNFT---QLLSNLSGSPGSCLEIG----NGETDSWFMPLTQQT 281
+P +++HG+GD C +S + + G LEIG +S+F+ + Q
Sbjct: 33 LPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQV 92
Query: 282 SLACEKVKMMKELSQGYNIVAQSQGNLVARGIIEFCDDAPPLINYVSLGGPHAGIAAIPK 461
+ C+ + +L QGYN + SQG R + + C +PP+IN +S+GG H G+ +P+
Sbjct: 93 TTVCQALAKDPKLQQGYNAMGFSQGGQFLRAVAQRC-PSPPMINLISVGGQHQGVFGLPR 151
Query: 462 C--SSGPFCAIAEALMKLEIYNDFVQDHIAPSGYVKIPGEMTKYLGHSKYLPKLNNERPD 635
C S C + Y+ VQ+ + + Y P + Y HS +L +N ER
Sbjct: 152 CPGESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQER-- 209
Query: 636 QRNSTFKDRFVSLHNLVLV--MNDTTLIPKETSWFGYY 743
N ++K ++L V+V +ND+ + P ++ WFG+Y
Sbjct: 210 GINESYKKNLMALKKFVMVKFLNDSIVDPVDSEWFGFY 247
>sp|Q8HXW6|PPT1_MACFA Palmitoyl-protein thioesterase 1 OS=Macaca fascicularis
GN=PPT1 PE=2 SV=1
Length = 306
Score = 106 bits (264), Expect = 3e-022
Identities = 63/218 (28%), Positives = 108/218 (49%), Gaps = 14/218 (6%)
Frame = +3
Query: 123 IPFILFHGIGDKCSGGVSNFT---QLLSNLSGSPGSCLEIG----NGETDSWFMPLTQQT 281
+P +++HG+GD C +S + + G LEIG +S+F+ + Q
Sbjct: 33 LPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQV 92
Query: 282 SLACEKVKMMKELSQGYNIVAQSQGNLVARGIIEFCDDAPPLINYVSLGGPHAGIAAIPK 461
+ C+ + +L QGYN + SQG R + + C +PP+IN +S+GG H G+ +P+
Sbjct: 93 TTVCQTLAKDPKLQQGYNAMGFSQGGQFLRAVAQRC-PSPPMINLISVGGQHQGVFGLPR 151
Query: 462 C--SSGPFCAIAEALMKLEIYNDFVQDHIAPSGYVKIPGEMTKYLGHSKYLPKLNNERPD 635
C S C + Y+ VQ+ + + Y P + Y HS +L +N ER
Sbjct: 152 CPGESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQER-- 209
Query: 636 QRNSTFKDRFVSLHNLVLV--MNDTTLIPKETSWFGYY 743
N ++K ++L V+V +ND+ + P ++ WFG+Y
Sbjct: 210 GINESYKKNLMALKKFVMVKFLNDSIVDPVDSEWFGFY 247
>sp|Q54CM0|PPT3_DICDI Palmitoyl-protein thioesterase 3 OS=Dictyostelium
discoideum GN=ppt3 PE=3 SV=1
Length = 289
Score = 102 bits (253), Expect = 5e-021
Identities = 70/245 (28%), Positives = 120/245 (48%), Gaps = 16/245 (6%)
Frame = +3
Query: 66 VLLLMVAAVLFSTVPVSNSIPFILFHGIGDKCSGGVSNFTQLLSNLSGSPGSC----LEI 233
+L ++ + + VS + P +L HG+ + G + L S + S +EI
Sbjct: 3 ILSSLILLIALAIALVSATRPVVLMHGV----TTGKESMEPLKSWIEESIPDIYVLNVEI 58
Query: 234 GNGETDSWFMPLTQQTSLACEKVKMMKELSQGYNIVAQSQGNLVARGIIEFCDDAPPLIN 413
GNG DS F + Q + V+ +L+ G+N++ SQG L+AR ++ ++ P + N
Sbjct: 59 GNGAFDSIFTTMDSQIEEFAQVVQADPKLANGFNLIGFSQGTLIARAFVQRYNN-PQVYN 117
Query: 414 YVSLGGPHAGIAAIPKCSSGPFCAIAEALMKLEIYNDFVQDHIAPSGYVKIPGEMTKYLG 593
Y+S GP G P + + ++ Y +Q ++ + Y K P + KYL
Sbjct: 118 YISWNGPQGGQFGTPFVN----IPWVDKVLGTIPYEKTIQKKLSVAEYWKDPHRIDKYLE 173
Query: 594 HSKYLPKLNNERPDQRNSTFKDRFVSLHNLVLV--MNDTTLIPKETSWFGYYSDDGFDSL 767
S +L +NNE +N+T+K+ L+ +VL ND T+IPKE+ WF +Y+D +
Sbjct: 174 RSIFLADINNEY-QVKNTTYKENLTKLNAMVLTYSTNDKTIIPKESGWFSFYADGSGTEV 232
Query: 768 LSTQQ 782
+ QQ
Sbjct: 233 VPLQQ 237
>sp|O88531|PPT1_MOUSE Palmitoyl-protein thioesterase 1 OS=Mus musculus GN=Ppt1
PE=2 SV=2
Length = 306
Score = 101 bits (250), Expect = 1e-020
Identities = 60/217 (27%), Positives = 107/217 (49%), Gaps = 14/217 (6%)
Frame = +3
Query: 126 PFILFHGIGDKCSGGVSNFT---QLLSNLSGSPGSCLEIGNGETD----SWFMPLTQQTS 284
P +++HG+GD C +S + + G LEIG + S+F+ + Q +
Sbjct: 34 PLVIWHGMGDSCCNPMSMGVIKKMVEKEIPGIYVLSLEIGKNMMEDVENSFFLNVNVQVN 93
Query: 285 LACEKVKMMKELSQGYNIVAQSQGNLVARGIIEFCDDAPPLINYVSLGGPHAGIAAIPKC 464
+ C+ ++ +L QGYN + SQG R + + C PP++ +S+GG H G+ +P+C
Sbjct: 94 MVCQILEKDPKLQQGYNAIGFSQGGQFLRAVAQRC-PTPPMMTLISVGGQHQGVFGLPRC 152
Query: 465 --SSGPFCAIAEALMKLEIYNDFVQDHIAPSGYVKIPGEMTKYLGHSKYLPKLNNERPDQ 638
S C + Y+ VQ+ + + Y P + + Y +S +L +N ER
Sbjct: 153 PGESSHICDFIRKSLNAGAYSKLVQERLVQAQYWHDPIKESVYRNYSIFLADINQER--C 210
Query: 639 RNSTFKDRFVSLHNLVLV--MNDTTLIPKETSWFGYY 743
N ++K ++L V+V ND+ + P ++ WFG+Y
Sbjct: 211 VNESYKKNLMALKKFVMVKFFNDSIVDPVDSEWFGFY 247
>sp|O59747|PDF1_SCHPO Palmitoyl-protein thioesterase-dolichyl pyrophosphate
phosphatase fusion 1 OS=Schizosaccharomyces pombe GN=pdf1 PE=1 SV=1
Length = 603
Score = 93 bits (230), Expect = 3e-018
Identities = 60/221 (27%), Positives = 112/221 (50%), Gaps = 10/221 (4%)
Frame = +3
Query: 114 SNSIPFILFHGIGD-KCSGGVSNFTQLLSNLSGSPGSCLEIGNGETD----SWFMPLTQQ 278
S +P +++HG+GD S ++ +Q + L+ + +G+ E + + L Q
Sbjct: 23 SEQLPVVIWHGLGDTPTSFTLTEVSQRVQKLTKGAVYAIRVGDNEFEDIKAGYLGKLEDQ 82
Query: 279 TSLACEKVKMMKELSQGYNIVAQSQGNLVARGIIEFCDDAPPLINYVSLGGPHAGIAAIP 458
C+ + LS G+ + SQG L R + + C DA + + ++LG PH+GI IP
Sbjct: 83 LDEVCDLIGNEDSLSNGFYALGLSQGGLFLRALAQTC-DAAKIRSLITLGSPHSGINTIP 141
Query: 459 KCS-SGPFC-AIAEALMKLEIYNDFVQDHIAPSGYVKIPGEMTKYLGHSKYLPKLNNERP 632
CS + C A+ +++ L I++ ++Q+H+ + Y + + KYL ++K+L LNNE
Sbjct: 142 GCSPTNLICKAVVHSILGLGIWHSWIQNHVVQAQYYRTEKQYDKYLENNKFLTHLNNEVL 201
Query: 633 DQRNSTFKDRFVSLHNLVLVM--NDTTLIPKETSWFGYYSD 749
+ ++ L NLV V D + P ++ FG+ ++
Sbjct: 202 HDNYTRNIEKLKELDNLVAVSFERDDIVEPPYSTGFGWINE 242
>sp|Q6GNY7|PPT2B_XENLA Lysosomal thioesterase PPT2-B OS=Xenopus laevis GN=ppt2-b
PE=2 SV=1
Length = 288
Score = 65 bits (157), Expect = 7e-010
Identities = 41/144 (28%), Positives = 75/144 (52%), Gaps = 4/144 (2%)
Frame = +3
Query: 324 QGYNIVAQSQGNLVARGIIEFCDDAPPLINYVSLGGPHAGIAAIPKCSSGPFCAIAEALM 503
+G +++ SQG L+ RG++E + + +++L P G + + + +
Sbjct: 89 KGVHLICYSQGGLICRGLLETMPE-HNVDTFIALSSPLMGQYGMTLYVQKALPLVNISAL 147
Query: 504 KLEIYNDFVQDHIAPSGYVKIPGEMTKYLGHSKYLPKLNNERPDQRNSTFKDRFVSLHNL 683
+ Y F ++ I+ GY + P KYL +S +LPKLNNE D ++ K F+ L L
Sbjct: 148 QEVCYRKFFKE-ISICGYWRDPHRYEKYLEYSAFLPKLNNELLDSNSTERKRNFLRLRKL 206
Query: 684 VLV--MNDTTLIPKETSWFGYYSD 749
VL+ +D + P ++S FG+Y++
Sbjct: 207 VLIGGPDDEVIAPWQSSHFGFYNE 230
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,099,029,888
Number of Sequences: 518415
Number of Extensions: 26099029888
Number of Successful Extensions: 175876120
Number of sequences better than 0.0: 0
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