BLASTX 7.6.2
Query= UN06480 /QuerySize=756
(755 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q09925|LCB2_SCHPO Serine palmitoyltransferase 2 OS=Schizosacc... 173 1e-042
sp|O54694|SPTC2_CRIGR Serine palmitoyltransferase 2 OS=Cricetulu... 164 5e-040
sp|P97363|SPTC2_MOUSE Serine palmitoyltransferase 2 OS=Mus muscu... 164 7e-040
sp|O15270|SPTC2_HUMAN Serine palmitoyltransferase 2 OS=Homo sapi... 163 2e-039
sp|Q54EX5|SPTC2_DICDI Serine palmitoyltransferase 2 OS=Dictyoste... 159 3e-038
sp|Q9NUV7|SPTC3_HUMAN Serine palmitoyltransferase 3 OS=Homo sapi... 151 6e-036
sp|P40970|LCB2_YEAST Serine palmitoyltransferase 2 OS=Saccharomy... 146 2e-034
sp|Q8BG54|SPTC3_MOUSE Serine palmitoyltransferase 3 OS=Mus muscu... 144 7e-034
sp|P48241|LCB2_KLULA Serine palmitoyltransferase 2 OS=Kluyveromy... 140 1e-032
sp|Q67N86|BIKB_SYMTH Putative 8-amino-7-oxononanoate synthase/2-... 78 6e-014
sp|Q5SHZ8|BIKB_THET8 8-amino-7-oxononanoate synthase/2-amino-3-k... 75 5e-013
sp|A6LMP4|BIKB_THEM4 Putative 8-amino-7-oxononanoate synthase/2-... 72 4e-012
sp|A6TU88|BIKB_ALKMQ Putative 8-amino-7-oxononanoate synthase/2-... 72 5e-012
sp|Q73KM3|BIKB_TREDE Putative 8-amino-7-oxononanoate synthase/2-... 70 2e-011
sp|B0K590|BIKB_THEPX Putative 8-amino-7-oxononanoate synthase/2-... 69 4e-011
sp|B0KC20|BIKB_THEP3 Putative 8-amino-7-oxononanoate synthase/2-... 68 5e-011
sp|B1YMC6|BIKB_EXIS2 Putative 8-amino-7-oxononanoate synthase/2-... 66 3e-010
sp|O66875|BIKB_AQUAE Putative 8-amino-7-oxononanoate synthase/2-... 65 3e-010
sp|Q5HIC5|BIKB_STAAC Putative 8-amino-7-oxononanoate synthase/2-... 65 6e-010
sp|P60121|BIKB_STAAM Putative 8-amino-7-oxononanoate synthase/2-... 65 6e-010
>sp|Q09925|LCB2_SCHPO Serine palmitoyltransferase 2 OS=Schizosaccharomyces pombe
GN=lcb2 PE=2 SV=1
Length = 603
Score = 173 bits (437), Expect = 1e-042
Identities = 89/201 (44%), Positives = 121/201 (60%), Gaps = 3/201 (1%)
Frame = +3
Query: 153 YLTAVSTYFSYGLLFAFGQLRDYTRLIF---DWCSTNNLHGYAPICLAHEDFYIRRLYHR 323
Y V+TY +Y +L G +RD+ F D+ + GYAP+ ++FY+RRL HR
Sbjct: 90 YYYVVATYLTYLVLIIIGHVRDFFGKRFHKDDYKYLKDNDGYAPLYNHFDNFYVRRLQHR 149
Query: 324 IQDCFNRPISSAPDSWVDVIERYSNDNNKTLKRTAKSTRCLNLGSYNYLGFGSFDEYCTP 503
I DCF+RP P + ++ RYS D+N T K T ++ LN+ SYNYLGF C
Sbjct: 150 INDCFSRPTMGVPGRVIRLMNRYSTDSNSTFKLTGDTSLALNVSSYNYLGFAQSHGPCAT 209
Query: 504 RVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIPVLI 683
+V E+++K+ STCSS GT +H E+EE A +VGKPAA+V GF+TN+ + L+
Sbjct: 210 KVEEAMQKYGLSTCSSNAICGTYGLHKEVEELTANFVGKPAALVFSQGFSTNATVFSTLM 269
Query: 684 GKGGLIISDSLNHTSIVNGAR 746
G LIISD LNHTSI GAR
Sbjct: 270 CPGSLIISDELNHTSIRFGAR 290
>sp|O54694|SPTC2_CRIGR Serine palmitoyltransferase 2 OS=Cricetulus griseus
GN=SPTLC2 PE=2 SV=1
Length = 560
Score = 164 bits (415), Expect = 5e-040
Identities = 93/208 (44%), Positives = 121/208 (58%), Gaps = 12/208 (5%)
Frame = +3
Query: 150 PYLTAVSTYFSYGLLFAFGQLRDYTRLIFDWCSTNNLHG--------YAPICLAHEDFYI 305
P L AV TY YG+L FG LRD+ R W H + + E+FY
Sbjct: 65 PMLVAVLTYVGYGVLTLFGYLRDFLR---HWRIEKCHHATEREEQKDFVSLYQDFENFYT 121
Query: 306 RRLYHRIQDCFNRPISSAPDSWVDVIERYSNDNNKTLKRTAKSTR-CLNLGSYNYLGFGS 482
R LY RI+D +NRPI S P + VD++ER S+D N + K T + +N+GSYNYLGF
Sbjct: 122 RNLYMRIRDNWNRPICSVPGARVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFAR 181
Query: 483 FDEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNS 662
C E LK++ CS+R + G H ELE+ VA+++G AA+ GMGFATNS
Sbjct: 182 NTGSCQEAAAEVLKEYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAAMTYGMGFATNS 241
Query: 663 VIIPVLIGKGGLIISDSLNHTSIVNGAR 746
+ IP L+GKG LI+SD LNH S+V GAR
Sbjct: 242 MNIPALVGKGCLILSDELNHASLVLGAR 269
>sp|P97363|SPTC2_MOUSE Serine palmitoyltransferase 2 OS=Mus musculus GN=Sptlc2
PE=2 SV=2
Length = 560
Score = 164 bits (414), Expect = 7e-040
Identities = 93/208 (44%), Positives = 121/208 (58%), Gaps = 12/208 (5%)
Frame = +3
Query: 150 PYLTAVSTYFSYGLLFAFGQLRDYTRLIFDWCSTNNLHG--------YAPICLAHEDFYI 305
P L AV TY YG+L FG LRD+ R W H + + E+FY
Sbjct: 65 PMLVAVLTYVGYGVLTLFGYLRDFLR---HWRIEKCHHATEREEQKDFVSLYQDFENFYT 121
Query: 306 RRLYHRIQDCFNRPISSAPDSWVDVIERYSNDNNKTLKRTAKSTR-CLNLGSYNYLGFGS 482
R LY RI+D +NRPI S P + VD++ER S+D N + K T + +N+GSYNYLGF
Sbjct: 122 RNLYMRIRDNWNRPICSVPGAKVDIMERKSHDYNWSFKYTGNIIKGVINMGSYNYLGFAR 181
Query: 483 FDEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNS 662
C E LK++ CS+R + G H ELE+ VA+++G AA+ GMGFATNS
Sbjct: 182 NTGSCQEAAAEVLKEYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAAMTYGMGFATNS 241
Query: 663 VIIPVLIGKGGLIISDSLNHTSIVNGAR 746
+ IP L+GKG LI+SD LNH S+V GAR
Sbjct: 242 MNIPALVGKGCLILSDELNHASLVLGAR 269
>sp|O15270|SPTC2_HUMAN Serine palmitoyltransferase 2 OS=Homo sapiens GN=SPTLC2
PE=1 SV=1
Length = 562
Score = 163 bits (411), Expect = 2e-039
Identities = 92/208 (44%), Positives = 121/208 (58%), Gaps = 12/208 (5%)
Frame = +3
Query: 150 PYLTAVSTYFSYGLLFAFGQLRDYTRLIFDWCSTNNLHG--------YAPICLAHEDFYI 305
P L AV TY YG+L FG LRD+ R W H + + E+FY
Sbjct: 67 PMLVAVLTYVGYGVLTLFGYLRDFLRY---WRIEKCHHATEREEQKDFVSLYQDFENFYT 123
Query: 306 RRLYHRIQDCFNRPISSAPDSWVDVIERYSNDNNKTLKRTAKSTR-CLNLGSYNYLGFGS 482
R LY RI+D +NRPI S P + VD++ER S+D N + K T + +N+GSYNYLGF
Sbjct: 124 RNLYMRIRDNWNRPICSVPGARVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFAR 183
Query: 483 FDEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNS 662
C + L+++ CS+R + G H ELEE VA+++G AA+ GMGFATNS
Sbjct: 184 NTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMAYGMGFATNS 243
Query: 663 VIIPVLIGKGGLIISDSLNHTSIVNGAR 746
+ IP L+GKG LI+SD LNH S+V GAR
Sbjct: 244 MNIPALVGKGCLILSDELNHASLVLGAR 271
>sp|Q54EX5|SPTC2_DICDI Serine palmitoyltransferase 2 OS=Dictyostelium discoideum
GN=sptB PE=1 SV=1
Length = 490
Score = 159 bits (400), Expect = 3e-038
Identities = 84/203 (41%), Positives = 123/203 (60%), Gaps = 1/203 (0%)
Frame = +3
Query: 147 IPYLTAVSTYFSYGLLFAFGQLRDYTRLIFDWCSTNNLHGYAPICLAHEDFYIRRLYHRI 326
+ YL + Y +Y + G+L ++ + + GYAP+ + E FY RR+Y RI
Sbjct: 13 VGYLPILFLYIAYAFIIFNGKLAEFIGKLKGERYLHTPEGYAPLFVEFEYFYQRRMYGRI 72
Query: 327 QDCFNRPISSAPDSWVDVIERYSNDNNKTLKRT-AKSTRCLNLGSYNYLGFGSFDEYCTP 503
+D ++RPI+S +W+DV+ R S ++ L+ T K+ +CLNLGSYNYLGF +
Sbjct: 73 KDAWDRPINSIAGAWIDVMPRASKHYSQRLELTGGKTIKCLNLGSYNYLGFAQNEGPVAD 132
Query: 504 RVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIPVLI 683
+VI+S+ K+ T S+ + G + +LE A++VGK AIV MGFATNS +P LI
Sbjct: 133 KVIDSIYKYGVYTGSTSAEVGLSEPQRDLENLTARFVGKEDAIVFEMGFATNSGTLPALI 192
Query: 684 GKGGLIISDSLNHTSIVNGARGS 752
GKGGLIISDSLNH S+ G + +
Sbjct: 193 GKGGLIISDSLNHASLATGCKNT 215
>sp|Q9NUV7|SPTC3_HUMAN Serine palmitoyltransferase 3 OS=Homo sapiens GN=SPTLC3
PE=1 SV=3
Length = 552
Score = 151 bits (380), Expect = 6e-036
Identities = 88/208 (42%), Positives = 122/208 (58%), Gaps = 12/208 (5%)
Frame = +3
Query: 150 PYLTAVSTYFSYGLLFAFGQLRDYTRLIFDW----CST----NNLHGYAPICLAHEDFYI 305
P V TY YG+ FG LRD+ R +W C+ + P+ E+FY
Sbjct: 59 PLHVMVFTYMGYGIGTLFGYLRDFLR---NWGIEKCNAAVERKEQKDFVPLYQDFENFYT 115
Query: 306 RRLYHRIQDCFNRPISSAPDSWVDVIERYSNDNNKTLKRTAKSTR-CLNLGSYNYLGFGS 482
R LY RI+D +NRPI SAP D++ER S+D N T + T + + +N+GSYN+LG +
Sbjct: 116 RNLYMRIRDNWNRPICSAPGPLFDLMERVSDDYNWTFRFTGRVIKDVINMGSYNFLGLAA 175
Query: 483 FDEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNS 662
+ + + L+ + S+R + GT H ELE+ VAK++ AA+V GMGFATNS
Sbjct: 176 KYDESMRTIKDVLEVYGTGVASTRHEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNS 235
Query: 663 VIIPVLIGKGGLIISDSLNHTSIVNGAR 746
+ IP L+GKG LI+SD LNHTS+V GAR
Sbjct: 236 MNIPALVGKGCLILSDELNHTSLVLGAR 263
>sp|P40970|LCB2_YEAST Serine palmitoyltransferase 2 OS=Saccharomyces cerevisiae
GN=LCB2 PE=1 SV=1
Length = 561
Score = 146 bits (367), Expect = 2e-034
Identities = 78/221 (35%), Positives = 120/221 (54%), Gaps = 3/221 (1%)
Frame = +3
Query: 93 HKPRERERRRRKEGIMITIPYLTAVSTYFSYGLLFAFGQLRDYTRLIFDWCSTNNL---H 263
++ + R + E ++ T PY ++ TY +Y +L G + D+ + F +L
Sbjct: 38 YQVKSRHGKPLPEPVVDTPPYYISLLTYLNYLILIILGHVHDFLGMTFQKNKHLDLLEHD 97
Query: 264 GYAPICLAHEDFYIRRLYHRIQDCFNRPISSAPDSWVDVIERYSNDNNKTLKRTAKSTRC 443
G AP E FY+RR+ RI DCF+RP + P ++ I+R S++ N+ + C
Sbjct: 98 GLAPWFSNFESFYVRRIKMRIDDCFSRPTTGVPGRFIRCIDRISHNINEYFTYSGAVYPC 157
Query: 444 LNLGSYNYLGFGSFDEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKP 623
+NL SYNYLGF CT +ES+ K+S + R GTT +H + E+ VA+++GK
Sbjct: 158 MNLSSYNYLGFAQSKGQCTDAALESVDKYSIQSGGPRAQIGTTDLHIKAEKLVARFIGKE 217
Query: 624 AAIVTGMGFATNSVIIPVLIGKGGLIISDSLNHTSIVNGAR 746
A+V MG+ TN+ + + K L+ISD LNHTSI G R
Sbjct: 218 DALVFSMGYGTNANLFNAFLDKKCLVISDELNHTSIRTGVR 258
>sp|Q8BG54|SPTC3_MOUSE Serine palmitoyltransferase 3 OS=Mus musculus GN=Sptlc3
PE=2 SV=1
Length = 563
Score = 144 bits (362), Expect = 7e-034
Identities = 85/232 (36%), Positives = 133/232 (57%), Gaps = 19/232 (8%)
Frame = +3
Query: 96 KPRERERRRRKEGIMITIPYLTA-----VSTYFSYGLLFAFGQLRDYTRLIFDW----CS 248
K ++ R+ E + PY A V TY YG+ FG LRD+ R +W C+
Sbjct: 36 KEAQQNRKAYAEDKPVFEPYQEAPLYVYVLTYMGYGIGILFGYLRDFMR---NWGIEKCN 92
Query: 249 T----NNLHGYAPICLAHEDFYIRRLYHRIQDCFNRPISSAPDSWVDVIERYSNDNNKTL 416
+ P+ E+FY R LY RI+D ++ + SAP+ +++V+E+ ++D N T
Sbjct: 93 AAVEREEQKDFVPLYQDFENFYKRNLYMRIRDSWSHTVCSAPEPYMNVMEKVTDDYNWTF 152
Query: 417 KRTAK-STRCLNLGSYNYLGF-GSFDEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAEL 590
+ T K +N+ SYNYLG G +D+ RV ++L+K+ S+R + GT +H EL
Sbjct: 153 RHTGKVIENIINMASYNYLGLAGKYDDSMV-RVKDTLEKYGVGVASTRNEMGTLDIHKEL 211
Query: 591 EECVAKYVGKPAAIVTGMGFATNSVIIPVLIGKGGLIISDSLNHTSIVNGAR 746
E+ +A+++ A + GMGFATN++ IPV +GKG LI+SD NHTS++ G+R
Sbjct: 212 EDLMAEFLNVEAVMSFGMGFATNAMNIPVFVGKGCLILSDEFNHTSVILGSR 263
>sp|P48241|LCB2_KLULA Serine palmitoyltransferase 2 OS=Kluyveromyces lactis
GN=LCB2 PE=3 SV=2
Length = 562
Score = 140 bits (352), Expect = 1e-032
Identities = 76/221 (34%), Positives = 117/221 (52%), Gaps = 3/221 (1%)
Frame = +3
Query: 93 HKPRERERRRRKEGIMITIPYLTAVSTYFSYGLLFAFGQLRDYTRLIFDWCSTNNL---H 263
++ + R+ + ++ I+ Y ++ TY +Y +L G + D+ L F ++
Sbjct: 37 YQSKSRDGKALQDPILDAPAYHVSLITYLNYLILIILGHIHDFLGLTFQKEKHKDIMEQD 96
Query: 264 GYAPICLAHEDFYIRRLYHRIQDCFNRPISSAPDSWVDVIERYSNDNNKTLKRTAKSTRC 443
G AP E FY+RRL RI DCF+RP + P ++ ++R S++ N ++ C
Sbjct: 97 GLAPWFSTFESFYVRRLKQRIDDCFSRPTTGVPGRFIRCLDRVSHNLNDYFTYPGTTSMC 156
Query: 444 LNLGSYNYLGFGSFDEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKP 623
LNL SYNYLGF + CT +E+ K+ + R GTT +H E+ VA++VGK
Sbjct: 157 LNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQFVGKE 216
Query: 624 AAIVTGMGFATNSVIIPVLIGKGGLIISDSLNHTSIVNGAR 746
AI+ MG+ TN+ + L+ISDSLNHTSI G R
Sbjct: 217 DAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVR 257
>sp|Q67N86|BIKB_SYMTH Putative 8-amino-7-oxononanoate
synthase/2-amino-3-ketobutyrate coenzyme A ligase OS=Symbiobacterium
thermophilum GN=STH1872 PE=3 SV=1
Length = 392
Score = 78 bits (190), Expect = 6e-014
Identities = 41/104 (39%), Positives = 63/104 (60%), Gaps = 1/104 (0%)
Frame = +3
Query: 444 LNLGSYNYLGFGSFDEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKP 623
+NL S NYLG D +IE+ + + + + R GT ++H +LE+ +A++
Sbjct: 42 INLSSNNYLGLAD-DPRLKQAMIEATEAYGAGSGAVRTIIGTMTIHNQLEQKLAEFKHVE 100
Query: 624 AAIVTGMGFATNSVIIPVLIGKGGLIISDSLNHTSIVNGARGSR 755
AA+V GF NS +IPVL+G+G +ISD LNH SI++G R S+
Sbjct: 101 AAVVFQSGFTCNSGVIPVLVGEGDAVISDELNHASIIDGCRLSK 144
>sp|Q5SHZ8|BIKB_THET8 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate
coenzyme A ligase OS=Thermus thermophilus (strain HB8 / ATCC 27634 /
DSM 579) GN=TTHA1582 PE=1 SV=1
Length = 395
Score = 75 bits (182), Expect = 5e-013
Identities = 38/101 (37%), Positives = 60/101 (59%), Gaps = 1/101 (0%)
Frame = +3
Query: 444 LNLGSYNYLGFGSFDEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKP 623
+NL S NYLGF + Y + + L+K+ + + R AGT + H ELEE +A++ G
Sbjct: 44 VNLASNNYLGFAN-HPYLKEKARQYLEKWGAGSGAVRTIAGTFTYHVELEEALARFKGTE 102
Query: 624 AAIVTGMGFATNSVIIPVLIGKGGLIISDSLNHTSIVNGAR 746
+A+V GF N ++ L+ +G ++ SD LNH SI++G R
Sbjct: 103 SALVLQSGFTANQGVLGALLKEGDVVFSDELNHASIIDGLR 143
>sp|A6LMP4|BIKB_THEM4 Putative 8-amino-7-oxononanoate
synthase/2-amino-3-ketobutyrate coenzyme A ligase OS=Thermosipho
melanesiensis (strain BI429 / DSM 12029) GN=Tmel_1346 PE=3 SV=1
Length = 391
Score = 72 bits (175), Expect = 4e-012
Identities = 41/106 (38%), Positives = 60/106 (56%), Gaps = 1/106 (0%)
Frame = +3
Query: 438 RCLNLGSYNYLGFGSFDEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVG 617
+ LNL S NYLGF + +E ++++K+ + R AGT S+H ELEE +AK+
Sbjct: 40 KVLNLCSNNYLGFAN-EERLKNAAKQAVEKWGVGPGAVRTIAGTFSLHNELEETLAKFKK 98
Query: 618 KPAAIVTGMGFATNSVIIPVLIGKGGLIISDSLNHTSIVNGARGSR 755
A I GF N +IP + + I+SD LNH SI++G R S+
Sbjct: 99 VEATIFLQSGFVANQAVIPAITNEEDAILSDELNHASIIDGVRLSK 144
>sp|A6TU88|BIKB_ALKMQ Putative 8-amino-7-oxononanoate
synthase/2-amino-3-ketobutyrate coenzyme A ligase OS=Alkaliphilus
metalliredigens (strain QYMF) GN=Amet_3634 PE=3 SV=1
Length = 395
Score = 72 bits (174), Expect = 5e-012
Identities = 40/106 (37%), Positives = 60/106 (56%), Gaps = 1/106 (0%)
Frame = +3
Query: 438 RCLNLGSYNYLGFGSFDEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVG 617
+ +NL S NYLGF + + I++++K+ + R G +H ELE +A++
Sbjct: 43 KVINLSSNNYLGFANHPQ-IKKAAIDAVEKYGVGAGAVRTIVGNMDIHEELERVLAEFKR 101
Query: 618 KPAAIVTGMGFATNSVIIPVLIGKGGLIISDSLNHTSIVNGARGSR 755
+ A +V GF N+ I + KG LIISD LNH SI++GAR SR
Sbjct: 102 EEAVMVFQSGFNCNAGTIQAVTEKGDLIISDQLNHASIIDGARLSR 147
>sp|Q73KM3|BIKB_TREDE Putative 8-amino-7-oxononanoate
synthase/2-amino-3-ketobutyrate coenzyme A ligase OS=Treponema
denticola GN=TDE_2194 PE=3 SV=1
Length = 395
Score = 70 bits (169), Expect = 2e-011
Identities = 38/106 (35%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
Frame = +3
Query: 438 RCLNLGSYNYLGFGSFDEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVG 617
+ +NL S NYLGF + IE+++K+ + R G +H +LE+ +A++
Sbjct: 43 KVINLSSNNYLGFANHPR-LKKAAIEAIEKYGAGAGAVRPIIGNMKIHDDLEKLLAEFKR 101
Query: 618 KPAAIVTGMGFATNSVIIPVLIGKGGLIISDSLNHTSIVNGARGSR 755
+ A + GF N+ +I L KG LIISD LNH SI++G R S+
Sbjct: 102 EEAVLAFQSGFNCNAGVIQALTDKGDLIISDQLNHASIIDGTRLSK 147
>sp|B0K590|BIKB_THEPX Putative 8-amino-7-oxononanoate
synthase/2-amino-3-ketobutyrate coenzyme A ligase OS=Thermoanaerobacter
sp. (strain X514) GN=Teth514_0779 PE=3 SV=1
Length = 395
Score = 69 bits (166), Expect = 4e-011
Identities = 37/106 (34%), Positives = 58/106 (54%), Gaps = 1/106 (0%)
Frame = +3
Query: 438 RCLNLGSYNYLGFGSFDEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVG 617
+ +NL S NYLG + IE+++K+ + R G ++H ELE +A++
Sbjct: 43 KVINLSSNNYLGLANHPR-LKKAAIEAIEKWGVGAGAVRTIIGNMTIHEELERKLAEFKR 101
Query: 618 KPAAIVTGMGFATNSVIIPVLIGKGGLIISDSLNHTSIVNGARGSR 755
+ A + GF N +I ++ KG +IISD LNH SI++G R SR
Sbjct: 102 EEAVLTFQSGFTANMGVIQAVVDKGDVIISDELNHASIIDGCRLSR 147
>sp|B0KC20|BIKB_THEP3 Putative 8-amino-7-oxononanoate
synthase/2-amino-3-ketobutyrate coenzyme A ligase OS=Thermoanaerobacter
pseudethanolicus (strain ATCC 33223 / 39E) GN=Teth39_0287 PE=3 SV=1
Length = 395
Score = 68 bits (165), Expect = 5e-011
Identities = 37/104 (35%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
Frame = +3
Query: 444 LNLGSYNYLGFGSFDEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKP 623
+NL S NYLG + IE+++K+ + R G ++H ELE +A++ +
Sbjct: 45 INLSSNNYLGLANHPR-LKKAAIEAIEKWGVGAGAVRTIIGNMTIHEELERKLAEFKREE 103
Query: 624 AAIVTGMGFATNSVIIPVLIGKGGLIISDSLNHTSIVNGARGSR 755
A + GF N +I ++ KG +IISD LNH SI++G R SR
Sbjct: 104 AVLTFQSGFTANMGVIQAVVDKGDVIISDELNHASIIDGCRLSR 147
>sp|B1YMC6|BIKB_EXIS2 Putative 8-amino-7-oxononanoate
synthase/2-amino-3-ketobutyrate coenzyme A ligase OS=Exiguobacterium
sibiricum (strain DSM 17290 / JCM 13490 / 255-15) GN=Exig_1033 PE=3
SV=1
Length = 390
Score = 66 bits (159), Expect = 3e-010
Identities = 38/108 (35%), Positives = 55/108 (50%), Gaps = 1/108 (0%)
Frame = +3
Query: 423 TAKSTRCLNLGSYNYLGFGSFDEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECV 602
T + L S NYLG + R ++ +F T S R AGT +H E +
Sbjct: 34 TVDGKELIQLSSNNYLGLAAHPR-LAKRAADAALEFGAGTGSVRTIAGTLEMHQAFEREL 92
Query: 603 AKYVGKPAAIVTGMGFATNSVIIPVLIGKGGLIISDSLNHTSIVNGAR 746
A + AA+V GFATN ++ L+G ++ISD+LNH SI++G R
Sbjct: 93 ATFKHTEAALVFQSGFATNLGVLSALLGPEDVVISDALNHASIIDGIR 140
>sp|O66875|BIKB_AQUAE Putative 8-amino-7-oxononanoate
synthase/2-amino-3-ketobutyrate coenzyme A ligase OS=Aquifex aeolicus
GN=aq_626 PE=3 SV=1
Length = 373
Score = 65 bits (158), Expect = 3e-010
Identities = 37/100 (37%), Positives = 57/100 (57%), Gaps = 1/100 (1%)
Frame = +3
Query: 456 SYNYLGFGSFDEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIV 635
S +YLG E I LK+ + +S++ +G T H ELEE +A++ G + ++
Sbjct: 31 SNDYLGLRKHPE-VVEESIRVLKEAGLGSGASQLVSGYTKHHRELEEKLAEFKGTESCVL 89
Query: 636 TGMGFATNSVIIPVLIGKGGLIISDSLNHTSIVNGARGSR 755
G GF N IP L+ +G L++SD LNH SI++G R S+
Sbjct: 90 FGSGFLANVGTIPALVEEGDLVLSDELNHASIIDGVRLSK 129
>sp|Q5HIC5|BIKB_STAAC Putative 8-amino-7-oxononanoate
synthase/2-amino-3-ketobutyrate coenzyme A ligase OS=Staphylococcus
aureus (strain COL) GN=SACOL0596 PE=3 SV=1
Length = 395
Score = 65 bits (156), Expect = 6e-010
Identities = 43/125 (34%), Positives = 60/125 (48%), Gaps = 3/125 (2%)
Frame = +3
Query: 381 IERYSNDNNKTLKRTAKSTRCLNLGSYNYLGFGSFDEYCTPRVIESLKKFSPSTCSSRVD 560
I+ N +K KS +NL S NYLG + +E ++ + R
Sbjct: 25 IDTIEGANGPEIKINGKS--YINLSSNNYLGLAT-NEDLKSAAKAAIDTHGVGAGAVRTI 81
Query: 561 AGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIPVLIGKGGLIISDSLNHTSIVNG 740
GT +H ELEE +AK+ G AAI GF N I ++ K I+SD LNH SI++G
Sbjct: 82 NGTLDLHDELEETLAKFKGTEAAIAYQSGFNCNMAAISAVMNKNDAILSDELNHASIIDG 141
Query: 741 ARGSR 755
R S+
Sbjct: 142 CRLSK 146
>sp|P60121|BIKB_STAAM Putative 8-amino-7-oxononanoate
synthase/2-amino-3-ketobutyrate coenzyme A ligase OS=Staphylococcus
aureus (strain Mu50 / ATCC 700699) GN=SAV0550 PE=1 SV=1
Length = 395
Score = 65 bits (156), Expect = 6e-010
Identities = 43/125 (34%), Positives = 60/125 (48%), Gaps = 3/125 (2%)
Frame = +3
Query: 381 IERYSNDNNKTLKRTAKSTRCLNLGSYNYLGFGSFDEYCTPRVIESLKKFSPSTCSSRVD 560
I+ N +K KS +NL S NYLG + +E ++ + R
Sbjct: 25 IDTIEGANGPEIKINGKS--YINLSSNNYLGLAT-NEDLKSAAKAAIDTHGVGAGAVRTI 81
Query: 561 AGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIPVLIGKGGLIISDSLNHTSIVNG 740
GT +H ELEE +AK+ G AAI GF N I ++ K I+SD LNH SI++G
Sbjct: 82 NGTLDLHDELEETLAKFKGTEAAIAYQSGFNCNMAAISAVMNKNDAILSDELNHASIIDG 141
Query: 741 ARGSR 755
R S+
Sbjct: 142 CRLSK 146
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,099,029,888
Number of Sequences: 518415
Number of Extensions: 26099029888
Number of Successful Extensions: 175876120
Number of sequences better than 0.0: 0
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