BLASTX 7.6.2
Query= UN06650 /QuerySize=1429
(1428 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q14974|IMB1_HUMAN Importin subunit beta-1 OS=Homo sapiens GN=... 151 1e-035
sp|P70168|IMB1_MOUSE Importin subunit beta-1 OS=Mus musculus GN=... 151 1e-035
sp|P52296|IMB1_RAT Importin subunit beta-1 OS=Rattus norvegicus ... 147 3e-034
sp|O18388|IMB_DROME Importin subunit beta OS=Drosophila melanoga... 146 5e-034
sp|O13864|IMB1_SCHPO Importin subunit beta-1 OS=Schizosaccharomy... 135 9e-031
>sp|Q14974|IMB1_HUMAN Importin subunit beta-1 OS=Homo sapiens GN=KPNB1 PE=1
SV=2
Length = 876
Score = 151 bits (381), Expect = 1e-035
Identities = 86/220 (39%), Positives = 133/220 (60%), Gaps = 10/220 (4%)
Frame = -3
Query: 1408 LSPYLTEIIQHLLATAERTDGAESKLRSASYETLNEVVRCSNLLEAAGIIGQLLPVIMGK 1229
LS I+Q LL T +R DG ++ LRS++YE+L E+V+ ++ + + + VIM +
Sbjct: 499 LSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVK-NSAKDCYPAVQKTTLVIMER 557
Query: 1228 LGQTIDLQ--VVSTEDREKQAELQASLCGVIQVIIQKLSSKDETKPIIMQNADHIMMLFL 1055
L Q + ++ + ST DR + +LQ+ LC +Q +++K+ +D +Q +D +M L
Sbjct: 558 LQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQD-----ALQISDVVMASLL 612
Query: 1054 RVF--GCHSSSVHEEAMLAIGALAYATGSEFAKYMPELFKYLQTGLQNFEEYQVCSITVG 881
R+F S V E+A++A+ L G EF KYM +L GL+N+ EYQVC VG
Sbjct: 613 RMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAEYQVCLAAVG 672
Query: 880 VVGDICRALDDKIPPFCDQIMSLLIQNLQSEALHRSVNLQ 761
+VGD+CRAL I PFCD++M LL++NL +E +HRSV Q
Sbjct: 673 LVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQ 712
Score = 92 bits (228), Expect = 6e-018
Identities = 55/165 (33%), Positives = 83/165 (50%), Gaps = 8/165 (4%)
Frame = -2
Query: 770 EPPIFSCFGDIALAIGGHFERYVATAIQIMQGAAHVCAQMDTLDEELMDYGNQLRRSIFE 591
+P I S FGDIALAIGG F++Y+ + +Q A+ AQ+D D +++DY N+LR S E
Sbjct: 710 KPQILSVFGDIALAIGGEFKKYLEVVLNTLQQASQ--AQVDKSDYDMVDYLNELRESCLE 767
Query: 590 AYSGILQGFKDAKAE------LMVPYAQHLLQFVELVSKDSLRDESVTKAAVAALGDLAD 429
AY+GI+QG K + L+ P + +L F++ ++ D + V A +GDL
Sbjct: 768 AYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCT 827
Query: 428 VVGEKTKPLFSNFTFCGEFLNECLDSEDEDLKDTARWTQGMIARL 294
G+ L E L E S+ K A W + +L
Sbjct: 828 AFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKL 872
>sp|P70168|IMB1_MOUSE Importin subunit beta-1 OS=Mus musculus GN=Kpnb1 PE=1
SV=1
Length = 876
Score = 151 bits (381), Expect = 1e-035
Identities = 86/220 (39%), Positives = 133/220 (60%), Gaps = 10/220 (4%)
Frame = -3
Query: 1408 LSPYLTEIIQHLLATAERTDGAESKLRSASYETLNEVVRCSNLLEAAGIIGQLLPVIMGK 1229
LS I+Q LL T +R DG ++ LRS++YE+L E+V+ ++ + + + VIM +
Sbjct: 499 LSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVK-NSAKDCYPAVQKTTLVIMER 557
Query: 1228 LGQTIDLQ--VVSTEDREKQAELQASLCGVIQVIIQKLSSKDETKPIIMQNADHIMMLFL 1055
L Q + ++ + ST DR + +LQ+ LC +Q +++K+ +D +Q +D +M L
Sbjct: 558 LQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQD-----ALQISDVVMASLL 612
Query: 1054 RVF--GCHSSSVHEEAMLAIGALAYATGSEFAKYMPELFKYLQTGLQNFEEYQVCSITVG 881
R+F S V E+A++A+ L G EF KYM +L GL+N+ EYQVC VG
Sbjct: 613 RMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAEYQVCLAAVG 672
Query: 880 VVGDICRALDDKIPPFCDQIMSLLIQNLQSEALHRSVNLQ 761
+VGD+CRAL I PFCD++M LL++NL +E +HRSV Q
Sbjct: 673 LVGDLCRALQSNILPFCDEVMQLLLENLGNENVHRSVKPQ 712
Score = 92 bits (227), Expect = 8e-018
Identities = 55/165 (33%), Positives = 83/165 (50%), Gaps = 8/165 (4%)
Frame = -2
Query: 770 EPPIFSCFGDIALAIGGHFERYVATAIQIMQGAAHVCAQMDTLDEELMDYGNQLRRSIFE 591
+P I S FGDIALAIGG F++Y+ + +Q A+ AQ+D D +++DY N+LR S E
Sbjct: 710 KPQILSVFGDIALAIGGEFKKYLEVVLNTLQQASQ--AQVDKSDFDMVDYLNELRESCLE 767
Query: 590 AYSGILQGFKDAKAE------LMVPYAQHLLQFVELVSKDSLRDESVTKAAVAALGDLAD 429
AY+GI+QG K + L+ P + +L F++ ++ D + V A +GDL
Sbjct: 768 AYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCT 827
Query: 428 VVGEKTKPLFSNFTFCGEFLNECLDSEDEDLKDTARWTQGMIARL 294
G+ L E L E S+ K A W + +L
Sbjct: 828 AFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKL 872
>sp|P52296|IMB1_RAT Importin subunit beta-1 OS=Rattus norvegicus GN=Kpnb1 PE=1
SV=1
Length = 875
Score = 147 bits (369), Expect = 3e-034
Identities = 85/220 (38%), Positives = 131/220 (59%), Gaps = 10/220 (4%)
Frame = -3
Query: 1408 LSPYLTEIIQHLLATAERTDGAESKLRSASYETLNEVVRCSNLLEAAGIIGQLLPVIMGK 1229
LS I+Q LL T +R DG ++ LRS++YE+L E+V+ ++ + + + VIM +
Sbjct: 498 LSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVK-NSAKDCYPAVQKTTLVIMER 556
Query: 1228 LGQTIDLQ--VVSTEDREKQAELQASLCGVIQVIIQKLSSKDETKPIIMQNADHIMMLFL 1055
L Q + ++ + ST DR + +LQ+ LC +Q ++ K+ +D +Q +D +M L
Sbjct: 557 LQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLWKVQHQD-----ALQISDVVMASLL 611
Query: 1054 RVF--GCHSSSVHEEAMLAIGALAYATGSEFAKYMPELFKYLQTGLQNFEEYQVCSITVG 881
R+F S V E+A++A+ L G EF KYM +L GL+N+ E QVC VG
Sbjct: 612 RMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAECQVCLAAVG 671
Query: 880 VVGDICRALDDKIPPFCDQIMSLLIQNLQSEALHRSVNLQ 761
+VGD+CRAL I PFCD++M LL++NL +E +HRSV Q
Sbjct: 672 LVGDLCRALQSNILPFCDEVMQLLLENLGNENVHRSVKPQ 711
Score = 91 bits (223), Expect = 2e-017
Identities = 54/165 (32%), Positives = 82/165 (49%), Gaps = 8/165 (4%)
Frame = -2
Query: 770 EPPIFSCFGDIALAIGGHFERYVATAIQIMQGAAHVCAQMDTLDEELMDYGNQLRRSIFE 591
+P I S FGDI LAIGG F++Y+ + +Q A+ AQ+D D +++DY N+LR S E
Sbjct: 709 KPQILSVFGDITLAIGGEFKKYLEVVLNTLQQASQ--AQVDKSDFDMVDYLNELRESCLE 766
Query: 590 AYSGILQGFKDAKAE------LMVPYAQHLLQFVELVSKDSLRDESVTKAAVAALGDLAD 429
AY+GI+QG K + L+ P + +L F++ ++ D + V A +GDL
Sbjct: 767 AYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCT 826
Query: 428 VVGEKTKPLFSNFTFCGEFLNECLDSEDEDLKDTARWTQGMIARL 294
G+ L E L E S+ K A W + +L
Sbjct: 827 AFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKL 871
>sp|O18388|IMB_DROME Importin subunit beta OS=Drosophila melanogaster
GN=Fs(2)Ket PE=1 SV=2
Length = 884
Score = 146 bits (367), Expect = 5e-034
Identities = 84/221 (38%), Positives = 132/221 (59%), Gaps = 11/221 (4%)
Frame = -3
Query: 1408 LSPYLTEIIQHLLATAERTDGAESKLRSASYETLNEVVRCSNLLEAAGIIGQLLPVIMGK 1229
LSPY II LL T +R+DGA++ LR A+Y+ L ++++ ++ L+ ++ + VI+ +
Sbjct: 504 LSPYFEYIITQLLETTDRSDGAQANLRCAAYQALMDMIK-NSPLDCYLVVQRTTLVILER 562
Query: 1228 LGQTIDL--QVVSTEDREKQAELQASLCGVIQVIIQKLSSKDETKPIIMQNADHIMMLFL 1055
L Q + + Q+ + DR + +LQ+ LC +Q +++K+ +D Q +D IM L
Sbjct: 563 LNQVMQMETQINNHSDRHQFNDLQSLLCATLQSVLRKVHEQDAP-----QISDAIMTALL 617
Query: 1054 RVFGC---HSSSVHEEAMLAIGALAYATGSEFAKYMPELFKYLQTGLQNFEEYQVCSITV 884
+F S V EEA LA+ L G++FAKYMP +L GL+NF+EYQVC V
Sbjct: 618 TMFNSSAGKSGVVQEEAFLAVSTLVELLGAQFAKYMPAFKDFLVMGLKNFQEYQVCCAAV 677
Query: 883 GVVGDICRALDDKIPPFCDQIMSLLIQNLQSEALHRSVNLQ 761
G+ GDI RAL D + P+ ++IM++LI NL +HR+V Q
Sbjct: 678 GLTGDIFRALKDLMVPYSNEIMTVLINNLTEPTIHRTVKPQ 718
Score = 84 bits (206), Expect = 2e-015
Identities = 51/165 (30%), Positives = 90/165 (54%), Gaps = 9/165 (5%)
Frame = -2
Query: 770 EPPIFSCFGDIALAIGGHFERYVATAIQIMQGAAHVCAQMDTLDEELMDYGNQLRRSIFE 591
+P + S FGDIAL+IG HF Y++ + +++ A+++ Q D + ++ +Y N+LR SI E
Sbjct: 716 KPQVLSAFGDIALSIGNHFLPYLSMVLDMLRVASNL--QTDANNFDMNEYINELRESILE 773
Query: 590 AYSGILQGFK--DAKAEL----MVPYAQHLLQFVELVSKDSLRDESVTKAAVAALGDLAD 429
AY+GI+QG K D A M P+ H++ F++ ++++ +S+ +A +GDL
Sbjct: 774 AYTGIIQGLKGVDQTAHTDVMHMEPHLMHIISFIKRIAQEGDVSDSMLASAAGFIGDLCT 833
Query: 428 VVGEKTKPLFSNFTFCGEFLNECLDSEDEDLKDTARWTQGMIARL 294
G + PL + +FL E S+ + K W I ++
Sbjct: 834 SFGPRLYPLLDD-AIITQFLAEGKRSKAQRTKMLCTWAVKEIKKI 877
>sp|O13864|IMB1_SCHPO Importin subunit beta-1 OS=Schizosaccharomyces pombe
GN=kap95 PE=2 SV=1
Length = 863
Score = 135 bits (339), Expect = 9e-031
Identities = 80/220 (36%), Positives = 129/220 (58%), Gaps = 12/220 (5%)
Frame = -3
Query: 1417 SSLLSPYLTEIIQHLLATAERTDGAESKLRSASYETLNEVVRCSNLLEAAGIIGQLLPVI 1238
+S+++P+ II LL ++ G E+ R++ YETL ++ S+ +I +L +I
Sbjct: 489 TSVMTPFYEAIIGSLLHVTDQ-KGNENNSRTSGYETLGTLITFSS-DSVLPMIANVLSII 546
Query: 1237 MGKLGQTIDL--QVVSTEDREKQAELQASLCGVIQVIIQKLSSKDETKPIIMQNADHIMM 1064
+ +L +I + Q++ EDR ELQ++LC V+ II++ P I ++D IM
Sbjct: 547 LTRLETSIQMQSQILDVEDRANHDELQSNLCNVLTSIIRRFG------PDIRTSSDQIMN 600
Query: 1063 LFLRVF--GCHSSSVHEEAMLAIGALAYATGSEFAKYMPELFKYLQTGLQNFEEYQVCSI 890
L L+ S VHE+ +LAIGA+ + +F Y+P +L + L N +EYQ+CS+
Sbjct: 601 LLLQTMQTAPKQSVVHEDVLLAIGAMMNSLEEQFEVYVPSFVPFLSSALSNEQEYQLCSV 660
Query: 889 TVGVVGDICRALDDKIPPFCDQIMSLLIQNLQSEALHRSV 770
VG+VGD+ RAL+ KI P+CD M+ L+Q+LQS L R+V
Sbjct: 661 AVGLVGDLARALNAKILPYCDDFMTRLVQDLQSSVLDRNV 700
Score = 82 bits (201), Expect = 9e-015
Identities = 53/164 (32%), Positives = 85/164 (51%), Gaps = 11/164 (6%)
Frame = -2
Query: 770 EPPIFSCFGDIALAIGGHFERYVATAIQIMQGAAHVCAQMDTLDEELMDYGNQLRRSIFE 591
+P I SCF DIALAIG F+ Y+ + ++Q A+ V A + ++DY + LR I E
Sbjct: 701 KPAILSCFSDIALAIGAAFQTYLEAVMVLLQQASSVQAPPGA-NFSMIDYVDALRLGIVE 759
Query: 590 AYSGILQGFK-DAKAELMVPYAQHLLQFVELVSKDSLRDESVTKAAVAALGDLADVVGEK 414
AY GI Q + D + +L+ PY + + +++ D ES+T+AA+ LGDLA+ +
Sbjct: 760 AYVGITQAVRTDNRLDLIQPYVHSMFTLLNMITADPECSESLTRAALGLLGDLAESFPKG 819
Query: 413 TKPLFSNFTFCGEFLNECLDS-----EDEDLKDTARWTQGMIAR 297
+ F +++ L+S + KD ARW + R
Sbjct: 820 ELKSY----FAADWVAALLNSGKTKISSQQTKDLARWATEQVKR 859
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,099,029,888
Number of Sequences: 518415
Number of Extensions: 26099029888
Number of Successful Extensions: 175876120
Number of sequences better than 0.0: 0
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