BLASTX 7.6.2
Query= UN07478 /QuerySize=1328
(1327 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9MA98|ERCC1_ARATH DNA excision repair protein ERCC-1 OS=Arab... 591 5e-168
sp|P07992|ERCC1_HUMAN DNA excision repair protein ERCC-1 OS=Homo... 240 2e-062
sp|Q1LZ75|ERCC1_BOVIN DNA excision repair protein ERCC-1 OS=Bos ... 235 7e-061
sp|P07903|ERCC1_MOUSE DNA excision repair protein ERCC-1 OS=Mus ... 233 2e-060
sp|Q06182|SWI10_SCHPO Mating-type switching protein swi10 OS=Sch... 195 1e-048
sp|Q55GG6|ERCC1_DICDI DNA excision repair protein ERCC-1 OS=Dict... 81 2e-014
sp|P06838|RAD10_YEAST DNA repair protein RAD10 OS=Saccharomyces ... 75 7e-013
>sp|Q9MA98|ERCC1_ARATH DNA excision repair protein ERCC-1 OS=Arabidopsis
thaliana GN=ERCC1 PE=2 SV=1
Length = 410
Score = 591 bits (1522), Expect = 5e-168
Identities = 307/367 (83%), Positives = 330/367 (89%), Gaps = 11/367 (2%)
Frame = +3
Query: 78 TLFKPSQTFSQAFAFVKSSDVYSPPPP-----PSQQPS-ASQVP-STSQTHQTDVASSSS 236
+LFKPSQ+FSQAFAFVKSSDVYSPPPP S QPS ASQVP S+SQTHQTD ASSSS
Sbjct: 48 SLFKPSQSFSQAFAFVKSSDVYSPPPPSSAAASSSQPSGASQVPHSSSQTHQTDGASSSS 107
Query: 237 SAPVATTGSLPSNTTQPRNAILVSNRQKGNPLLKHIRNVKWVYSDIIPDYLLGQTTCALY 416
+ PVA TGS+PSNTTQ RNAILVS+RQKGNPLLKHIRNVKWV+SDIIPDY+LGQ +CALY
Sbjct: 108 T-PVA-TGSVPSNTTQNRNAILVSHRQKGNPLLKHIRNVKWVFSDIIPDYVLGQNSCALY 165
Query: 417 LSLRYHLLHPDYLYFRIRELQRNFKLRVVLCHVDVEDSVKPLLEVTKTALLHDCTLLCAW 596
LSLRYHLLHPDYLYFRIRELQ+NFKL VVLCHVDVED+VKPLLEVTKTALLHDCTLLCAW
Sbjct: 166 LSLRYHLLHPDYLYFRIRELQKNFKLSVVLCHVDVEDTVKPLLEVTKTALLHDCTLLCAW 225
Query: 597 SLTECARYLETIKVYENKPADLIQGQMDTDYLSRLNHSLTSIRHVNKSDVVTLGSTFGSL 776
S+TECARYLETIKVYENKPADLIQGQMDTDYLSRLNHSLTSIRHVNKSDVVTLGSTFGSL
Sbjct: 226 SMTECARYLETIKVYENKPADLIQGQMDTDYLSRLNHSLTSIRHVNKSDVVTLGSTFGSL 285
Query: 777 AHIMDASMEDLARCPGIGERKVKRLYDTFHEPFKRAASSYPSVIEPTVPQTEVHKGGNSE 956
AHI+DASMEDLARCPGIGERKVKRLYDTFHEPFKRA SSYPSV+EP +P+ V K NSE
Sbjct: 286 AHIIDASMEDLARCPGIGERKVKRLYDTFHEPFKRATSSYPSVVEPPIPEAPVEKDVNSE 345
Query: 957 ERVVEADEDFVEEDSRKRMKKVEPEKNVKTALSTVFARYFDGLCKKKEKQKEKDTATESD 1136
E VE DEDFVE+ +++ K+ EPEK VKTALS VFARY D L KKKEKQKEKDT T SD
Sbjct: 346 E-PVEEDEDFVEDSRKRKKKEPEPEKTVKTALSAVFARYSDRLSKKKEKQKEKDTTTASD 404
Query: 1137 AEVTHKD 1157
AE TH++
Sbjct: 405 AE-THQN 410
Score = 57 bits (137), Expect = 2e-007
Identities = 35/74 (47%), Positives = 45/74 (60%), Gaps = 2/74 (2%)
Frame = +2
Query: 2 KTQIVIGVPSYQEVLESSQTKSTPPYSLQTFPDFLSSFRF--RQILRRLLSSSSSVAAAQ 175
KTQIVIGVPSYQEVLESSQTKSTPP + F +F F + SS+ A++
Sbjct: 23 KTQIVIGVPSYQEVLESSQTKSTPPSLFKPSQSFSQAFAFVKSSDVYSPPPPSSAAASSS 82
Query: 176 RFSSAQYKPNASDR 217
+ S A P++S +
Sbjct: 83 QPSGASQVPHSSSQ 96
>sp|P07992|ERCC1_HUMAN DNA excision repair protein ERCC-1 OS=Homo sapiens
GN=ERCC1 PE=1 SV=1
Length = 297
Score = 240 bits (611), Expect = 2e-062
Identities = 115/218 (52%), Positives = 158/218 (72%), Gaps = 5/218 (2%)
Frame = +3
Query: 231 SSSAPVATTGSLPSNTTQP---RNAILVSNRQKGNPLLKHIRNVKWVYSDIIPDYLLGQT 401
+ S P+A G P+ +P N+I+VS RQ+GNP+LK +RNV W + D+IPDY+LGQ+
Sbjct: 78 TGSEPLA--GETPNQALKPGAKSNSIIVSPRQRGNPVLKFVRNVPWEFGDVIPDYVLGQS 135
Query: 402 TCALYLSLRYHLLHPDYLYFRIRELQRNFKLRVVLCHVDVEDSVKPLLEVTKTALLHDCT 581
TCAL+LSLRYH LHPDY++ R++ L +NF LRV+L VDV+D + L E+ K +L DCT
Sbjct: 136 TCALFLSLRYHNLHPDYIHGRLQSLGKNFALRVLLVQVDVKDPQQALKELAKMCILADCT 195
Query: 582 LLCAWSLTECARYLETIKVYENKPADLIQGQMDTDYLSRLNHSLTSIRHVNKSDVVTLGS 761
L+ AWS E RYLET K YE KPADL+ +++ D++SR+ LT+++ VNK+D TL +
Sbjct: 196 LILAWSPEEAGRYLETYKAYEQKPADLLMEKLEQDFVSRVTECLTTVKSVNKTDSQTLLT 255
Query: 762 TFGSLAHIMDASMEDLARCPGIGERKVKRLYDTFHEPF 875
TFGSL ++ AS EDLA CPG+G +K +RL+D HEPF
Sbjct: 256 TFGSLEQLIAASREDLALCPGLGPQKARRLFDVLHEPF 293
>sp|Q1LZ75|ERCC1_BOVIN DNA excision repair protein ERCC-1 OS=Bos taurus GN=ERCC1
PE=2 SV=1
Length = 294
Score = 235 bits (598), Expect = 7e-061
Identities = 116/257 (45%), Positives = 165/257 (64%), Gaps = 6/257 (2%)
Frame = +3
Query: 114 FAFVKSSDVYSPPPPPSQQPSASQVPSTSQTHQTDVASSSSSAPVATTGSLPSNTTQP-- 287
F +S PPP Q A S ++ P P+ +P
Sbjct: 36 FRSTRSLPTVETSPPPGPQTYAEYALSGP---PGGAEATRPVGPEPLAEETPNQAPKPGA 92
Query: 288 -RNAILVSNRQKGNPLLKHIRNVKWVYSDIIPDYLLGQTTCALYLSLRYHLLHPDYLYFR 464
N+I+VS RQ+GNP+L+ +RNV W + D++PDY+LGQ+TCAL+LSLRYH LHPDY++ R
Sbjct: 93 KSNSIIVSPRQRGNPVLRFVRNVPWEFGDVLPDYVLGQSTCALFLSLRYHNLHPDYIHQR 152
Query: 465 IRELQRNFKLRVVLCHVDVEDSVKPLLEVTKTALLHDCTLLCAWSLTECARYLETIKVYE 644
++ L +++ LRV+L VDV+D + L E+ K +L DCTL+ AWS E RYLET K YE
Sbjct: 153 LQSLGKSYALRVLLVQVDVKDPQQALKELAKMCILADCTLILAWSPEEAGRYLETYKAYE 212
Query: 645 NKPADLIQGQMDTDYLSRLNHSLTSIRHVNKSDVVTLGSTFGSLAHIMDASMEDLARCPG 824
KPADL+ +++ D++SR+ LT+++ VNK+D TL +TFGSL ++ AS EDL+ CPG
Sbjct: 213 QKPADLLMEKLEQDFVSRVTECLTTVKSVNKTDSQTLLTTFGSLEQLIAASREDLSLCPG 272
Query: 825 IGERKVKRLYDTFHEPF 875
+G +K +RL+D FHEPF
Sbjct: 273 LGPQKARRLFDVFHEPF 289
>sp|P07903|ERCC1_MOUSE DNA excision repair protein ERCC-1 OS=Mus musculus
GN=Ercc1 PE=2 SV=1
Length = 298
Score = 233 bits (594), Expect = 2e-060
Identities = 113/218 (51%), Positives = 155/218 (71%), Gaps = 5/218 (2%)
Frame = +3
Query: 231 SSSAPVATTGSLPSNTTQ---PRNAILVSNRQKGNPLLKHIRNVKWVYSDIIPDYLLGQT 401
+ S P A G PS T + N+I+VS RQ+GNP+LK +RNV W + ++IPDY+LGQ+
Sbjct: 78 TGSEPAA--GENPSQTLKTGAKSNSIIVSPRQRGNPVLKFVRNVPWEFGEVIPDYVLGQS 135
Query: 402 TCALYLSLRYHLLHPDYLYFRIRELQRNFKLRVVLCHVDVEDSVKPLLEVTKTALLHDCT 581
TCAL+LSLRYH LHPDY++ R++ L +NF LRV+L VDV+D + L E+ K +L DCT
Sbjct: 136 TCALFLSLRYHNLHPDYIHERLQSLGKNFALRVLLVQVDVKDPQQALKELAKMCILADCT 195
Query: 582 LLCAWSLTECARYLETIKVYENKPADLIQGQMDTDYLSRLNHSLTSIRHVNKSDVVTLGS 761
L+ AWS E RYLET + YE KPADL+ +++ ++LSR LT+++ VNK+D TL +
Sbjct: 196 LVLAWSAEEAGRYLETYRAYEQKPADLLMEKLEQNFLSRATECLTTVKSVNKTDSQTLLA 255
Query: 762 TFGSLAHIMDASMEDLARCPGIGERKVKRLYDTFHEPF 875
TFGSL + AS EDLA CPG+G +K +RL++ HEPF
Sbjct: 256 TFGSLEQLFTASREDLALCPGLGPQKARRLFEVLHEPF 293
>sp|Q06182|SWI10_SCHPO Mating-type switching protein swi10
OS=Schizosaccharomyces pombe GN=swi10 PE=2 SV=1
Length = 252
Score = 195 bits (493), Expect = 1e-048
Identities = 95/195 (48%), Positives = 135/195 (69%)
Frame = +3
Query: 291 NAILVSNRQKGNPLLKHIRNVKWVYSDIIPDYLLGQTTCALYLSLRYHLLHPDYLYFRIR 470
++ILV+ RQKGNPLL H+RNV W Y+DI+PD+++G C+L+LSL+YH LHP+Y+Y RI
Sbjct: 41 HSILVNPRQKGNPLLPHVRNVPWEYTDIVPDFVMGTGICSLFLSLKYHHLHPEYIYSRIS 100
Query: 471 ELQRNFKLRVVLCHVDVEDSVKPLLEVTKTALLHDCTLLCAWSLTECARYLETIKVYENK 650
+L +++ LR++L VDVE+ + E+ KT++++ TL+ AWS E ARYLET K YEN
Sbjct: 101 KLGKSYNLRILLILVDVENHQASIQELVKTSIVNQYTLILAWSSEEAARYLETYKAYENM 160
Query: 651 PADLIQGQMDTDYLSRLNHSLTSIRHVNKSDVVTLGSTFGSLAHIMDASMEDLARCPGIG 830
LI + TDYLS++ LTSIR +NKSD ++L S FGSL + AS ++L + G G
Sbjct: 161 SPALIMEKPSTDYLSQVQSFLTSIRGINKSDSLSLLSKFGSLERALVASRDELEQLEGWG 220
Query: 831 ERKVKRLYDTFHEPF 875
KV R + +PF
Sbjct: 221 PTKVNRFLEAVQQPF 235
>sp|Q55GG6|ERCC1_DICDI DNA excision repair protein ERCC-1 OS=Dictyostelium
discoideum GN=ercc1 PE=3 SV=1
Length = 514
Score = 81 bits (198), Expect = 2e-014
Identities = 50/155 (32%), Positives = 78/155 (50%), Gaps = 6/155 (3%)
Frame = +3
Query: 483 NFKLRVVLCHVDVEDS---VKPLLEVTKTALLHDCTLLCAWSLTECARYLETIKVYENKP 653
+F LR++L D+ DS + + E+ A+ TL+ WS E A+YLE K + N+
Sbjct: 288 SFTLRILLVFADLSDSDNCEQFINELNLIAIKLQFTLIVCWSQIEAAKYLEAYKTFNNRA 347
Query: 654 ADLIQGQMDTDYL---SRLNHSLTSIRHVNKSDVVTLGSTFGSLAHIMDASMEDLARCPG 824
D I+ + L S+ LTSI+ VNK+D TL F ++ I L++ PG
Sbjct: 348 PDPIKARAQPIELGGKSKNEQVLTSIKSVNKTDATTLLKNFQTMQQIFTCQKTTLSKLPG 407
Query: 825 IGERKVKRLYDTFHEPFKRAASSYPSVIEPTVPQT 929
G KV++ Y+T ++PFK S+ + T T
Sbjct: 408 FGPVKVQKFYNTINQPFKTKPSTKTTTTTTTTTTT 442
>sp|P06838|RAD10_YEAST DNA repair protein RAD10 OS=Saccharomyces cerevisiae
GN=RAD10 PE=1 SV=1
Length = 210
Score = 75 bits (184), Expect = 7e-013
Identities = 51/178 (28%), Positives = 93/178 (52%), Gaps = 9/178 (5%)
Frame = +3
Query: 123 VKSSDVYSPPPPPSQQPSASQVPSTSQTHQTDVASSSSSAPVATTGSLPSNTTQPRNAIL 302
+ +S + P S++ +++QV + Q + S A P +T+P +L
Sbjct: 36 IDASKLQQQEPQTSRRINSNQV-INAFNQQKPEEWTDSKATDDYNRKRPFRSTRPGKTVL 94
Query: 303 VSNRQKGNPLLKHIRNVKWVY------SDIIPDYLLGQTTCALYLSLRYHLLHPDYLYFR 464
V+ QK NPLL H+++ W Y + I DYL+ + L+L+L YH L+ DY+ R
Sbjct: 95 VNTTQKENPLLNHLKSTNWRYVSSTGINMIYYDYLV-RGRSVLFLTLTYHKLYVDYISRR 153
Query: 465 IRELQRNFKLRVVLCHVDVEDSVKPLLEVTKTALLHDCTLLCAWSLTECARYLETIKV 638
++ L RN + +++ VD +S L ++TK + + TLL A++ + A+Y+E + +
Sbjct: 154 MQPLSRN-ENNILIFIVDDNNSEDTLNDITKLCMFNGFTLLLAFNFEQAAKYIEYLNL 210
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,803,502,693
Number of Sequences: 518415
Number of Extensions: 29803502693
Number of Successful Extensions: 223310478
Number of sequences better than 0.0: 0
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