BLASTX 7.6.2
Query= UN07764 /QuerySize=1464
(1463 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sap... 100 3e-020
sp|Q3UHJ0|AAK1_MOUSE AP2-associated protein kinase 1 OS=Mus musc... 98 1e-019
sp|Q86HW6|Y6461_DICDI Probable serine/threonine-protein kinase D... 97 3e-019
sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sap... 94 2e-018
sp|P0C1X8|AAK1_RAT AP2-associated protein kinase 1 OS=Rattus nor... 92 9e-018
sp|Q91Z96|BMP2K_MOUSE BMP-2-inducible protein kinase OS=Mus musc... 91 1e-017
sp|O14976|GAK_HUMAN Cyclin-G-associated kinase OS=Homo sapiens G... 91 2e-017
sp|P40494|PRK1_YEAST Actin-regulating kinase PRK1 OS=Saccharomyc... 89 6e-017
sp|Q54VV7|Y0111_DICDI Probable serine/threonine-protein kinase D... 89 6e-017
sp|P97874|GAK_RAT Cyclin-G-associated kinase OS=Rattus norvegicu... 88 1e-016
sp|P53974|ARK1_YEAST Actin-regulating kinase 1 OS=Saccharomyces ... 87 3e-016
sp|Q99KY4|GAK_MOUSE Cyclin-G-associated kinase OS=Mus musculus G... 83 4e-015
sp|O43066|PPK30_SCHPO Serine/threonine-protein kinase ppk30 OS=S... 82 7e-015
sp|P38080|AKL1_YEAST Serine/threonine-protein kinase AKL1 OS=Sac... 79 6e-014
sp|Q9USS2|PPK29_SCHPO Serine/threonine-protein kinase ppk29 OS=S... 77 4e-013
sp|Q9UU85|PPK38_SCHPO Protein kinase domain-containing protein p... 75 1e-012
sp|P57760|STK16_RAT Serine/threonine-protein kinase 16 OS=Rattus... 66 5e-010
sp|O75716|STK16_HUMAN Serine/threonine-protein kinase 16 OS=Homo... 66 7e-010
sp|O88697|STK16_MOUSE Serine/threonine-protein kinase 16 OS=Mus ... 66 7e-010
sp|Q10078|PPK13_SCHPO Serine/threonine-protein kinase ppk13 OS=S... 65 1e-009
>sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1
PE=1 SV=3
Length = 961
Score = 100 bits (248), Expect = 3e-020
Identities = 47/88 (53%), Positives = 66/88 (75%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 TTPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFDGESKLQVLNGNYRIPES 180
TT +YRAPEM +L+ +II+ K DIWALGCLLY++CYF F GES++ + +GN+ IP++
Sbjct: 221 TTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPF-GESQVAICDGNFTIPDN 279
Query: 181 PKYSSSVTDLIRDMLQGSPDERPDVTQV 264
+YS + LIR ML+ PD+RPD+ QV
Sbjct: 280 SRYSQDMHCLIRYMLEPDPDKRPDIYQV 307
>sp|Q3UHJ0|AAK1_MOUSE AP2-associated protein kinase 1 OS=Mus musculus GN=Aak1
PE=1 SV=2
Length = 959
Score = 98 bits (243), Expect = 1e-019
Identities = 46/88 (52%), Positives = 66/88 (75%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 TTPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFDGESKLQVLNGNYRIPES 180
TT +YRAPEM +L+ +II+ K DIWALGCLLY++CYF F GES++ + +G++ IP++
Sbjct: 221 TTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPF-GESQVAICDGSFTIPDN 279
Query: 181 PKYSSSVTDLIRDMLQGSPDERPDVTQV 264
+YS + LIR ML+ PD+RPD+ QV
Sbjct: 280 SRYSQDMHCLIRYMLEPDPDKRPDIYQV 307
>sp|Q86HW6|Y6461_DICDI Probable serine/threonine-protein kinase DDB_G0276461
OS=Dictyostelium discoideum GN=DDB_G0276461 PE=3 SV=1
Length = 798
Score = 97 bits (240), Expect = 3e-019
Identities = 45/94 (47%), Positives = 67/94 (71%), Gaps = 1/94 (1%)
Frame = +1
Query: 1 TTPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFDGESKLQVLNGNYRIPES 180
TT YRAPEM DL+R +II EKVD+WALGCLL+++ ++ FDG S LQ++N NY+IP++
Sbjct: 230 TTLFYRAPEMVDLYRGQIIDEKVDVWALGCLLFKMAFYVDPFDGGS-LQIINNNYKIPDN 288
Query: 181 PKYSSSVTDLIRDMLQGSPDERPDVTQVWFRVNQ 282
KYS++ LI+ +L P +RP + + +N+
Sbjct: 289 SKYSNNFHKLIQFILVADPTQRPSINDLLNYLNE 322
>sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K
PE=1 SV=2
Length = 1161
Score = 94 bits (233), Expect = 2e-018
Identities = 44/88 (50%), Positives = 65/88 (73%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 TTPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFDGESKLQVLNGNYRIPES 180
TT +YRAPEM +L+ + I+ K DIWALGCLLY++C+F F GES++ + +GN+ IP++
Sbjct: 225 TTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPF-GESQVAICDGNFTIPDN 283
Query: 181 PKYSSSVTDLIRDMLQGSPDERPDVTQV 264
+YS ++ LIR ML+ P+ RPD+ QV
Sbjct: 284 SRYSRNIHCLIRFMLEPDPEHRPDIFQV 311
>sp|P0C1X8|AAK1_RAT AP2-associated protein kinase 1 OS=Rattus norvegicus GN=Aak1
PE=1 SV=1
Length = 962
Score = 92 bits (227), Expect = 9e-018
Identities = 45/88 (51%), Positives = 65/88 (73%), Gaps = 2/88 (2%)
Frame = +1
Query: 1 TTPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFDGESKLQVLNGNYRIPES 180
TT +YRAPEM +L+ +II+ K DIWALGCLLY++CYF F GES++ + +G++ IP++
Sbjct: 221 TTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPF-GESQVAICDGSFTIPDN 279
Query: 181 PKYSSSVTDLIRDMLQGSPDERPDVTQV 264
+YS + LI ML+ PD+RPD+ QV
Sbjct: 280 SRYSQDMHCLIY-MLEPDPDKRPDIYQV 306
>sp|Q91Z96|BMP2K_MOUSE BMP-2-inducible protein kinase OS=Mus musculus GN=Bmp2k
PE=1 SV=1
Length = 1138
Score = 91 bits (225), Expect = 1e-017
Identities = 44/88 (50%), Positives = 65/88 (73%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 TTPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFDGESKLQVLNGNYRIPES 180
TT +YRAPEM +L+ + I+ K DIWALGCLLY++C+F F GES++ + +G++ IP++
Sbjct: 222 TTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPF-GESQVAICDGSFTIPDN 280
Query: 181 PKYSSSVTDLIRDMLQGSPDERPDVTQV 264
+YS +V LIR ML+ P+ RPD+ QV
Sbjct: 281 SRYSHNVHCLIRFMLEPDPECRPDIFQV 308
>sp|O14976|GAK_HUMAN Cyclin-G-associated kinase OS=Homo sapiens GN=GAK PE=1
SV=2
Length = 1311
Score = 91 bits (223), Expect = 2e-017
Identities = 51/142 (35%), Positives = 75/142 (52%), Gaps = 6/142 (4%)
Frame = +1
Query: 1 TTPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFDGESKLQVLNGNYRIPES 180
TTP YR PE+ DL+ I EK DIWALGC+LY +C+ + F+ +KL+++NG Y IP
Sbjct: 222 TTPMYRTPEIIDLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPPH 281
Query: 181 PKYSSSVTDLIRDMLQGSPDERPDVTQVWFRVNQQLPANLQKSLPDGPPEMQSTDGSSSK 360
+ LIR MLQ +P+ER + +V ++ + A + P+ T+
Sbjct: 282 DTQYTVFHSLIRAMLQVNPEERLSIAEVVHQLQEIAAAR------NVNPKSPITELLEQN 335
Query: 361 PASKSSPAPRRSPPPPPPSSSG 426
S+ R PPP P+ SG
Sbjct: 336 GGYGSATLSRGPPPPVGPAGSG 357
>sp|P40494|PRK1_YEAST Actin-regulating kinase PRK1 OS=Saccharomyces cerevisiae
GN=PRK1 PE=1 SV=1
Length = 810
Score = 89 bits (220), Expect = 6e-017
Identities = 42/94 (44%), Positives = 61/94 (64%)
Frame = +1
Query: 1 TTPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFDGESKLQVLNGNYRIPES 180
TT YR+PEM DL+R I EK DIWALG LY+ICY+ + F+ + +L+ Y+ P
Sbjct: 204 TTAQYRSPEMIDLYRGLPIDEKSDIWALGVFLYKICYYTTPFEKSGEAGILHARYQYPSF 263
Query: 181 PKYSSSVTDLIRDMLQGSPDERPDVTQVWFRVNQ 282
P+YS + +LIR ML +P +RP++ QV V++
Sbjct: 264 PQYSDRLKNLIRLMLMEAPSQRPNICQVLEEVSR 297
>sp|Q54VV7|Y0111_DICDI Probable serine/threonine-protein kinase DDB_G0280111
OS=Dictyostelium discoideum GN=DDB_G0280111 PE=3 SV=1
Length = 1126
Score = 89 bits (220), Expect = 6e-017
Identities = 39/93 (41%), Positives = 62/93 (66%)
Frame = +1
Query: 1 TTPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFDGESKLQVLNGNYRIPES 180
TT YRAPE+ D +R +I+EK+DIWALGCLLY++ ++ + F+ L +LN NY IP +
Sbjct: 194 TTLQYRAPEIVDFYRSPVINEKIDIWALGCLLYKLLFYVTPFEDSGSLGILNSNYTIPPN 253
Query: 181 PKYSSSVTDLIRDMLQGSPDERPDVTQVWFRVN 279
+S+ + LI+ ML P RP++ ++ ++N
Sbjct: 254 HTHSNDLISLIKIMLNPDPINRPNIFEITNQLN 286
>sp|P97874|GAK_RAT Cyclin-G-associated kinase OS=Rattus norvegicus GN=Gak PE=2
SV=1
Length = 1305
Score = 88 bits (217), Expect = 1e-016
Identities = 52/142 (36%), Positives = 78/142 (54%), Gaps = 5/142 (3%)
Frame = +1
Query: 1 TTPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFDGESKLQVLNGNYRIPES 180
TTP YR PE+ DL+ I EK DIWALGC+LY +C+ + F+ +KL+++NG Y IP +
Sbjct: 222 TTPMYRTPEIVDLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPVN 281
Query: 181 PKYSSSVTDLIRDMLQGSPDERPDVTQVWFRVNQQLPANLQKSLPDGPPEMQSTDGSSSK 360
+ DLIR ML+ +P+ER + +V R Q++ A + E+ +G
Sbjct: 282 DTRYTVFHDLIRGMLKVNPEERLSIAEV-VRQLQEIAAARNVNPKAPITELLEQNGG--- 337
Query: 361 PASKSSPAPRRSPPPPPPSSSG 426
S P+ + P P +SSG
Sbjct: 338 -YGNSGPSRAQPPSGGPVNSSG 358
>sp|P53974|ARK1_YEAST Actin-regulating kinase 1 OS=Saccharomyces cerevisiae
GN=ARK1 PE=1 SV=1
Length = 638
Score = 87 bits (214), Expect = 3e-016
Identities = 42/93 (45%), Positives = 57/93 (61%)
Frame = +1
Query: 1 TTPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFDGESKLQVLNGNYRIPES 180
TT YR+PEM D FR I EK DIWALG LY++CY+ + F+ L +L+G + P
Sbjct: 205 TTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYYTTPFEKGGDLAILSGKFEFPLY 264
Query: 181 PKYSSSVTDLIRDMLQGSPDERPDVTQVWFRVN 279
P YS + LIRD+L P RP+V Q+ R++
Sbjct: 265 PNYSEQLKGLIRDILVQDPRHRPNVYQLLKRIS 297
>sp|Q99KY4|GAK_MOUSE Cyclin-G-associated kinase OS=Mus musculus GN=Gak PE=1
SV=2
Length = 1305
Score = 83 bits (204), Expect = 4e-015
Identities = 40/88 (45%), Positives = 57/88 (64%)
Frame = +1
Query: 1 TTPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFDGESKLQVLNGNYRIPES 180
TTP YR PE+ DL+ I EK DIWALGC+LY +C+ + F+ +KL+++NG Y IP +
Sbjct: 222 TTPMYRTPEIVDLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPVN 281
Query: 181 PKYSSSVTDLIRDMLQGSPDERPDVTQV 264
+ DLIR ML+ +P ER + +V
Sbjct: 282 DTRYTVFHDLIRAMLKVNPVERLSIAEV 309
>sp|O43066|PPK30_SCHPO Serine/threonine-protein kinase ppk30
OS=Schizosaccharomyces pombe GN=ppk30 PE=1 SV=1
Length = 953
Score = 82 bits (202), Expect = 7e-015
Identities = 41/106 (38%), Positives = 59/106 (55%), Gaps = 2/106 (1%)
Frame = +1
Query: 1 TTPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFDGESKLQVLNGNYRIPES 180
TTP YRAPEM D+ RR+ I EK DIWA+G L Y++CY+ + F+ +L ++ P
Sbjct: 233 TTPQYRAPEMIDINRRQGIDEKSDIWAIGVLAYKLCYYTTPFEQVGNSAILKASFSFPPF 292
Query: 181 PKYSSSVTDLIRDMLQGSPDERPDVTQVWFRVNQQLPANLQKSLPD 318
P+YS + I LQ P RP++ Q + + L+ LPD
Sbjct: 293 PRYSDRMKRFIATCLQEQPSHRPNIYQTLKEIMEMQGTPLK--LPD 336
>sp|P38080|AKL1_YEAST Serine/threonine-protein kinase AKL1 OS=Saccharomyces
cerevisiae GN=AKL1 PE=1 SV=1
Length = 1108
Score = 79 bits (194), Expect = 6e-014
Identities = 40/92 (43%), Positives = 60/92 (65%), Gaps = 1/92 (1%)
Frame = +1
Query: 1 TTPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFDGESKLQVLNGNYRIPES 180
TTP YR+PEM DL+R I+EK DIWALG LY++ +F + F+ + +L+ Y P +
Sbjct: 227 TTPQYRSPEMIDLYRCLPINEKSDIWALGVFLYKLLFFTTPFEMTGQFAILHSKYEFPVN 286
Query: 181 PKYSSSVTDLIRDMLQGSPDERPDVTQVWFRV 276
KYSS + +LI ML +P+ RP++ QV + +
Sbjct: 287 -KYSSKLINLIIIMLAENPNLRPNIYQVLYHL 317
>sp|Q9USS2|PPK29_SCHPO Serine/threonine-protein kinase ppk29
OS=Schizosaccharomyces pombe GN=ppk29 PE=1 SV=1
Length = 872
Score = 77 bits (187), Expect = 4e-013
Identities = 37/88 (42%), Positives = 56/88 (63%)
Frame = +1
Query: 1 TTPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFDGESKLQVLNGNYRIPES 180
TT YRAPEM +L+ I EK D+WALG LLY++CY+ + F+ + +L +Y P
Sbjct: 208 TTYQYRAPEMINLYSGLGIDEKSDMWALGVLLYKLCYYTTPFETQGPNAILTASYSFPPF 267
Query: 181 PKYSSSVTDLIRDMLQGSPDERPDVTQV 264
P YS S+ ++I +LQ +P RP++ Q+
Sbjct: 268 PPYSHSLKNVIIALLQPNPCLRPNIFQL 295
>sp|Q9UU85|PPK38_SCHPO Protein kinase domain-containing protein ppk38
OS=Schizosaccharomyces pombe GN=ppk38 PE=2 SV=1
Length = 650
Score = 75 bits (183), Expect = 1e-012
Identities = 54/206 (26%), Positives = 91/206 (44%), Gaps = 2/206 (0%)
Frame = +1
Query: 1 TTPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFDGESKLQVLNGNYRIPES 180
TT YR PEM ++ + I EK DIWALG L Y++CY+ + F+ + ++N +Y P
Sbjct: 212 TTWQYRCPEMINVHKGFGIDEKSDIWALGVLFYKLCYYTTPFEHQGLAAIMNVSYAFPTF 271
Query: 181 PKYSSSVTDLIRDMLQGSPDERPDVTQVWFRVNQQLPANLQKSLPDGPPEMQSTDGSSSK 360
P YS + LI +LQ P +RP++ Q + + + + + S + S S+
Sbjct: 272 PPYSDRLKRLISTLLQQYPWQRPNIYQTFCEICKMRNVPIHIYDIYNGKNVSSCNPSGSE 331
Query: 361 PASKSSPAPRRSPPPPPPSSSGEQASGGGPLGAFWATQHAQTSVVSEDNNTNIAKKPSPV 540
+S S + AS P+ + +S ++ N SPV
Sbjct: 332 YLQHASKLENSGIHQSKSSVFPQPASAMKPMASPMLPNVNSMPYLSNGDHNNNGNTSSPV 391
Query: 541 RGEARGKDTS--PAAAAASNRARVSK 612
+ G+ TS P+ + RV++
Sbjct: 392 SRFSYGQHTSNVPSTQKLPSNFRVTQ 417
>sp|P57760|STK16_RAT Serine/threonine-protein kinase 16 OS=Rattus norvegicus
GN=Stk16 PE=2 SV=2
Length = 305
Score = 66 bits (160), Expect = 5e-010
Identities = 29/89 (32%), Positives = 54/89 (60%), Gaps = 5/89 (5%)
Frame = +1
Query: 4 TPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFD-----GESKLQVLNGNYR 168
T +YRAPE++ + +I E+ D+W+LGC+LY + + + +D G+S + +
Sbjct: 195 TISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNDLS 254
Query: 169 IPESPKYSSSVTDLIRDMLQGSPDERPDV 255
IP+SP++SS++ L+ M+ P +RP +
Sbjct: 255 IPQSPRHSSALRQLLASMMTVDPQQRPHI 283
>sp|O75716|STK16_HUMAN Serine/threonine-protein kinase 16 OS=Homo sapiens
GN=STK16 PE=1 SV=4
Length = 305
Score = 66 bits (159), Expect = 7e-010
Identities = 29/89 (32%), Positives = 53/89 (59%), Gaps = 5/89 (5%)
Frame = +1
Query: 4 TPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFD-----GESKLQVLNGNYR 168
T +YRAPE++ + +I E+ D+W+LGC+LY + + + +D G+S +
Sbjct: 195 TISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLS 254
Query: 169 IPESPKYSSSVTDLIRDMLQGSPDERPDV 255
IP+SP++SS++ L+ M+ P +RP +
Sbjct: 255 IPQSPRHSSALRQLLNSMMTVDPHQRPHI 283
>sp|O88697|STK16_MOUSE Serine/threonine-protein kinase 16 OS=Mus musculus
GN=Stk16 PE=2 SV=3
Length = 305
Score = 66 bits (159), Expect = 7e-010
Identities = 29/89 (32%), Positives = 53/89 (59%), Gaps = 5/89 (5%)
Frame = +1
Query: 4 TPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFD-----GESKLQVLNGNYR 168
T +YRAPE++ + +I E+ D+W+LGC+LY + + + +D G+S +
Sbjct: 195 TISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNELS 254
Query: 169 IPESPKYSSSVTDLIRDMLQGSPDERPDV 255
IP+SP++SS++ L+ M+ P +RP +
Sbjct: 255 IPQSPRHSSALRQLLSSMMTVDPQQRPHI 283
>sp|Q10078|PPK13_SCHPO Serine/threonine-protein kinase ppk13
OS=Schizosaccharomyces pombe GN=ppk13 PE=2 SV=2
Length = 344
Score = 65 bits (157), Expect = 1e-009
Identities = 32/101 (31%), Positives = 53/101 (52%), Gaps = 6/101 (5%)
Frame = +1
Query: 4 TPAYRAPEMWDLFRREIISEKVDIWALGCLLYRICYFKSAFD------GESKLQVLNGNY 165
T +RAPE++ + I+EK DIW+ GC LY I + S F+ G L V N Y
Sbjct: 242 TMPFRAPELFHVKAGSTITEKADIWSFGCTLYTIMFHASPFEREVSQGGSLALAVCNAQY 301
Query: 166 RIPESPKYSSSVTDLIRDMLQGSPDERPDVTQVWFRVNQQL 288
P YS+ + +++ LQ P++RP ++ +++ Q+
Sbjct: 302 SFPRKHPYSTLLCEIVEACLQREPNKRPSARELLSKIDLQI 342
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,733,448,049
Number of Sequences: 518415
Number of Extensions: 32733448049
Number of Successful Extensions: 231167770
Number of sequences better than 0.0: 0
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