BLASTX 7.6.2
Query= UN08062 /QuerySize=1224
(1223 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5ZIW5|VAC14_CHICK Protein VAC14 homolog OS=Gallus gallus GN=... 194 1e-048
sp|Q66L58|VAC14_DANRE Protein VAC14 homolog OS=Danio rerio GN=va... 193 3e-048
sp|Q08AM6|VAC14_HUMAN Protein VAC14 homolog OS=Homo sapiens GN=V... 193 4e-048
sp|Q80WQ2|VAC14_MOUSE Protein VAC14 homolog OS=Mus musculus GN=V... 191 1e-047
sp|Q80W92|VAC14_RAT Protein VAC14 homolog OS=Rattus norvegicus G... 191 1e-047
sp|A2VE70|VAC14_BOVIN Protein VAC14 homolog OS=Bos taurus GN=VAC... 191 1e-047
sp|Q68F38|VAC14_XENLA Protein VAC14 homolog OS=Xenopus laevis GN... 191 1e-047
sp|P87145|VAC14_SCHPO Protein VAC14 homolog OS=Schizosaccharomyc... 181 1e-044
sp|Q06708|VAC14_YEAST Vacuole morphology and inheritance protein... 141 1e-032
>sp|Q5ZIW5|VAC14_CHICK Protein VAC14 homolog OS=Gallus gallus GN=VAC14 PE=2
SV=1
Length = 780
Score = 194 bits (492), Expect = 1e-048
Identities = 104/222 (46%), Positives = 146/222 (65%), Gaps = 9/222 (4%)
Frame = -3
Query: 1221 IHNFRADNSLLERRGALIIRRLCVLLDAERVYRELSTILEGEDNLDFASTMVQALNLILL 1042
+ F ++ LLE RGA IIR+LC+LL+ E ++ ++ IL E++L FASTMV LN ILL
Sbjct: 533 LKRFSSERKLLETRGAFIIRQLCLLLNTENIFHSMADILLREEDLKFASTMVHTLNTILL 592
Query: 1041 TSSELSRLRNLLRGSLVNREGKELFVALYASWCHSPIAIISLCLLSQAYQHASVVIQSLV 862
TSSEL +LRN L+ L E + LF LY SWCH+P+ +SLC L+Q Y+HA +IQ
Sbjct: 593 TSSELFQLRNQLK-DLRTPESRNLFCCLYRSWCHNPVTTVSLCFLTQNYKHAYDLIQKFG 651
Query: 861 EEDMNVKFFVQLDKLIRLLETPIFTYLRLQLLEPGRYPWLLKTLYGLLMLLPQQSAAFRI 682
+ ++ V F ++DKL++L+E PIFTYLRLQLL+ P+L+K LYGLLMLLP QS+AF++
Sbjct: 652 DLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLP-QSSAFQL 710
Query: 681 LETRLKTVPTYSISGGGD-------QIRRAFSGVSFSQYMHH 577
L RL+ VP + D R A S + +++ + H
Sbjct: 711 LSHRLQCVPNPELMQSADGSRASASSRRPASSTIDYTELLQH 752
>sp|Q66L58|VAC14_DANRE Protein VAC14 homolog OS=Danio rerio GN=vac14 PE=2 SV=1
Length = 771
Score = 193 bits (489), Expect = 3e-048
Identities = 101/189 (53%), Positives = 136/189 (71%), Gaps = 2/189 (1%)
Frame = -3
Query: 1221 IHNFRADNSLLERRGALIIRRLCVLLDAERVYRELSTILEGEDNLDFASTMVQALNLILL 1042
+ F + LLE RGA IIR+LC+LL AE ++ ++ IL E++L FASTMVQ LN ILL
Sbjct: 525 LKRFSLERKLLEMRGAFIIRQLCLLLHAENIFHSMADILLKEEDLKFASTMVQTLNTILL 584
Query: 1041 TSSELSRLRNLLRGSLVNREGKELFVALYASWCHSPIAIISLCLLSQAYQHASVVIQSLV 862
TS+EL +LRN L+ L +E LF LY SWCH+P+A +SLC L+Q Y+HA +IQ
Sbjct: 585 TSAELFQLRNQLK-DLRTQESCALFCCLYRSWCHNPVATVSLCFLTQNYRHAYDLIQKFG 643
Query: 861 EEDMNVKFFVQLDKLIRLLETPIFTYLRLQLLEPGRYPWLLKTLYGLLMLLPQQSAAFRI 682
+ ++ V F +++DKL++L+E+PIFTYLRLQLL+ P+L+K LYGLLMLLP QS AF++
Sbjct: 644 DLEVTVDFLMEVDKLVQLIESPIFTYLRLQLLDVEHNPYLIKALYGLLMLLP-QSQAFQL 702
Query: 681 LETRLKTVP 655
L RL VP
Sbjct: 703 LSHRLSCVP 711
>sp|Q08AM6|VAC14_HUMAN Protein VAC14 homolog OS=Homo sapiens GN=VAC14 PE=1 SV=1
Length = 782
Score = 193 bits (488), Expect = 4e-048
Identities = 101/203 (49%), Positives = 141/203 (69%), Gaps = 2/203 (0%)
Frame = -3
Query: 1221 IHNFRADNSLLERRGALIIRRLCVLLDAERVYRELSTILEGEDNLDFASTMVQALNLILL 1042
+ F ++ LLE RG IIR+LC+LL+AE ++ ++ IL E++L FASTMV ALN ILL
Sbjct: 535 LKRFSSERKLLEVRGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHALNTILL 594
Query: 1041 TSSELSRLRNLLRGSLVNREGKELFVALYASWCHSPIAIISLCLLSQAYQHASVVIQSLV 862
TS+EL +LRN L+ L E + LF LY SWCH+P+ +SLC L+Q Y+HA +IQ
Sbjct: 595 TSTELFQLRNQLK-DLKTLESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRHAYDLIQKFG 653
Query: 861 EEDMNVKFFVQLDKLIRLLETPIFTYLRLQLLEPGRYPWLLKTLYGLLMLLPQQSAAFRI 682
+ ++ V F ++DKL++L+E PIFTYLRLQLL+ P+L+K LYGLLMLLP QS+AF++
Sbjct: 654 DLEVTVDFLAEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLP-QSSAFQL 712
Query: 681 LETRLKTVPTYSISGGGDQIRRA 613
L RL+ VP + D ++ A
Sbjct: 713 LSHRLQCVPNPELLQTEDSLKAA 735
>sp|Q80WQ2|VAC14_MOUSE Protein VAC14 homolog OS=Mus musculus GN=Vac14 PE=1 SV=1
Length = 782
Score = 191 bits (484), Expect = 1e-047
Identities = 100/203 (49%), Positives = 140/203 (68%), Gaps = 2/203 (0%)
Frame = -3
Query: 1221 IHNFRADNSLLERRGALIIRRLCVLLDAERVYRELSTILEGEDNLDFASTMVQALNLILL 1042
+ F ++ LLE RG IIR+LC+LL+AE ++ ++ IL E++L FASTMV LN ILL
Sbjct: 535 LQTFSSERKLLEARGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHTLNTILL 594
Query: 1041 TSSELSRLRNLLRGSLVNREGKELFVALYASWCHSPIAIISLCLLSQAYQHASVVIQSLV 862
TS+EL +LRN L+ L E + LF LY SWCH+P+ +SLC L+Q Y+HA +IQ
Sbjct: 595 TSTELFQLRNQLK-DLQTPESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRHAYDLIQKFG 653
Query: 861 EEDMNVKFFVQLDKLIRLLETPIFTYLRLQLLEPGRYPWLLKTLYGLLMLLPQQSAAFRI 682
+ ++ V F ++DKL++L+E PIFTYLRLQLL+ P+L+K LYGLLMLLP QS+AF++
Sbjct: 654 DLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLP-QSSAFQL 712
Query: 681 LETRLKTVPTYSISGGGDQIRRA 613
L RL+ VP + D ++ A
Sbjct: 713 LSHRLQCVPNPELLQTEDCLKAA 735
>sp|Q80W92|VAC14_RAT Protein VAC14 homolog OS=Rattus norvegicus GN=Vac14 PE=1
SV=1
Length = 783
Score = 191 bits (484), Expect = 1e-047
Identities = 100/203 (49%), Positives = 140/203 (68%), Gaps = 2/203 (0%)
Frame = -3
Query: 1221 IHNFRADNSLLERRGALIIRRLCVLLDAERVYRELSTILEGEDNLDFASTMVQALNLILL 1042
+ F ++ LLE RG IIR+LC+LL+AE ++ ++ IL E++L FASTMV LN ILL
Sbjct: 536 LQTFSSERKLLEARGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHTLNTILL 595
Query: 1041 TSSELSRLRNLLRGSLVNREGKELFVALYASWCHSPIAIISLCLLSQAYQHASVVIQSLV 862
TS+EL +LRN L+ L E + LF LY SWCH+P+ +SLC L+Q Y+HA +IQ
Sbjct: 596 TSTELFQLRNQLK-DLKTLESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRHAYDLIQKFG 654
Query: 861 EEDMNVKFFVQLDKLIRLLETPIFTYLRLQLLEPGRYPWLLKTLYGLLMLLPQQSAAFRI 682
+ ++ V F ++DKL++L+E PIFTYLRLQLL+ P+L+K LYGLLMLLP QS+AF++
Sbjct: 655 DLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLMKALYGLLMLLP-QSSAFQL 713
Query: 681 LETRLKTVPTYSISGGGDQIRRA 613
L RL+ VP + D ++ A
Sbjct: 714 LSHRLQCVPNPELLQTEDCLKAA 736
>sp|A2VE70|VAC14_BOVIN Protein VAC14 homolog OS=Bos taurus GN=VAC14 PE=2 SV=1
Length = 783
Score = 191 bits (483), Expect = 1e-047
Identities = 101/203 (49%), Positives = 139/203 (68%), Gaps = 2/203 (0%)
Frame = -3
Query: 1221 IHNFRADNSLLERRGALIIRRLCVLLDAERVYRELSTILEGEDNLDFASTMVQALNLILL 1042
+ F ++ LLE RGA IIR+LC+LL AE ++ ++ IL E++L FASTMV LN ILL
Sbjct: 536 LKRFSSERKLLEVRGAFIIRQLCLLLHAESIFHSMADILLREEDLTFASTMVHTLNTILL 595
Query: 1041 TSSELSRLRNLLRGSLVNREGKELFVALYASWCHSPIAIISLCLLSQAYQHASVVIQSLV 862
TS+EL +LRN L+ L E + LF LY SWCH P+ +SLC L+Q Y+HA +IQ
Sbjct: 596 TSTELFQLRNQLK-DLKTPESRNLFCCLYRSWCHKPVTTVSLCFLTQNYRHAYDLIQKFG 654
Query: 861 EEDMNVKFFVQLDKLIRLLETPIFTYLRLQLLEPGRYPWLLKTLYGLLMLLPQQSAAFRI 682
+ ++ V F ++DKL++L+E PIFTYLRLQLL+ P+L+K LYGLLMLLP QS+AF++
Sbjct: 655 DLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKSNPYLIKALYGLLMLLP-QSSAFQL 713
Query: 681 LETRLKTVPTYSISGGGDQIRRA 613
L RL+ VP + D ++ A
Sbjct: 714 LSHRLQCVPNPELLQTEDGLKAA 736
>sp|Q68F38|VAC14_XENLA Protein VAC14 homolog OS=Xenopus laevis GN=vac14 PE=2
SV=1
Length = 782
Score = 191 bits (483), Expect = 1e-047
Identities = 101/189 (53%), Positives = 136/189 (71%), Gaps = 2/189 (1%)
Frame = -3
Query: 1221 IHNFRADNSLLERRGALIIRRLCVLLDAERVYRELSTILEGEDNLDFASTMVQALNLILL 1042
+ F + LLE RGA IIR+LC+LL+AE ++ ++ IL E++L FASTMVQ LN ILL
Sbjct: 535 LKRFSNERKLLEIRGAFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVQNLNSILL 594
Query: 1041 TSSELSRLRNLLRGSLVNREGKELFVALYASWCHSPIAIISLCLLSQAYQHASVVIQSLV 862
TSSEL +LR+ L+ L E LF LY SWCH+P+A +SLC L+Q YQHA +IQ
Sbjct: 595 TSSELFQLRSQLK-DLQTPESCNLFCCLYRSWCHNPVATVSLCFLTQNYQHAYNLIQKFG 653
Query: 861 EEDMNVKFFVQLDKLIRLLETPIFTYLRLQLLEPGRYPWLLKTLYGLLMLLPQQSAAFRI 682
+ ++ V F ++DKL++L+E PIFTYLRLQLL+ P+L++ LYGLLMLLP QS+AF++
Sbjct: 654 DLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVENNPYLIRALYGLLMLLP-QSSAFQL 712
Query: 681 LETRLKTVP 655
L RL+ VP
Sbjct: 713 LSHRLQCVP 721
>sp|P87145|VAC14_SCHPO Protein VAC14 homolog OS=Schizosaccharomyces pombe
GN=SPBC25H2.03 PE=2 SV=1
Length = 811
Score = 181 bits (458), Expect = 1e-044
Identities = 94/187 (50%), Positives = 126/187 (67%), Gaps = 3/187 (1%)
Frame = -3
Query: 1212 FRADNSLLERRGALIIRRLCVLLDAERVYRELSTILEGEDNLDFASTMVQALNLILLTSS 1033
F D L RG LIIR+LC ++ ERVY + ILE E+NL+ AS MV+ LN L T+
Sbjct: 524 FAEDRKFLNSRGNLIIRQLCNYIEGERVYTSFAGILETEENLELASIMVEVLNNNLFTAP 583
Query: 1032 ELSRLRNLLRGSLVNREGKELFVALYASWCHSPIAIISLCLLSQAYQHASVVIQSLVEED 853
EL LR L+ S + +F LY +WCH+ IA+ SLCLLSQ Y+HA+ ++ E +
Sbjct: 584 ELYDLRKKLKQSAPKLQ--NIFTTLYTAWCHNSIAVFSLCLLSQNYEHAANLLSVFAEIE 641
Query: 852 MNVKFFVQLDKLIRLLETPIFTYLRLQLLEPGRYPWLLKTLYGLLMLLPQQSAAFRILET 673
N+ +QLDKL++L+E+P+FTY+RLQLLEP +YP+L K LYG+LMLLP QS+AFR L
Sbjct: 642 FNIDMLIQLDKLVQLIESPVFTYMRLQLLEPEKYPYLHKALYGILMLLP-QSSAFRTLRD 700
Query: 672 RLKTVPT 652
RL+ T
Sbjct: 701 RLQCSST 707
>sp|Q06708|VAC14_YEAST Vacuole morphology and inheritance protein 14
OS=Saccharomyces cerevisiae GN=VAC14 PE=1 SV=1
Length = 880
Score = 141 bits (354), Expect = 1e-032
Identities = 75/185 (40%), Positives = 119/185 (64%), Gaps = 5/185 (2%)
Frame = -3
Query: 1212 FRADNSLLERRGALIIRRLCVLLDAERVYRELSTILEGEDNLDFASTMVQALNLILLTSS 1033
F+ D L++ R I+R++ L ERVY+ +S+IL+ ++ F M+Q L+ L+TS
Sbjct: 568 FKRDTKLVKTRANFIMRQISSRLSPERVYKVISSILDNYNDTTFVKMMIQILSTNLITSP 627
Query: 1032 ELSRLRNLLRGSLVNREGKELFVALYASWCHSPIAIISLCLLSQAYQHASVVIQSLVEED 853
E+S LRN LR E F +L+ SWC +P+++ISLC +++ Y+ A V+Q+ +
Sbjct: 628 EMSSLRNKLR----TCEDGMFFNSLFKSWCPNPVSVISLCFVAENYELAYTVLQTYANYE 683
Query: 852 MNVKFFVQLDKLIRLLETPIFTYLRLQLLEPGRYPWLLKTLYGLLMLLPQQSAAFRILET 673
+ + VQLD LI+L E+P+FT +RLQLLE ++P+L K L+G+LM++P QS AF L
Sbjct: 684 LKLNDLVQLDILIQLFESPVFTRMRLQLLEQQKHPFLHKCLFGILMIIP-QSKAFETLNR 742
Query: 672 RLKTV 658
RL ++
Sbjct: 743 RLNSL 747
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,733,448,049
Number of Sequences: 518415
Number of Extensions: 32733448049
Number of Successful Extensions: 231167770
Number of sequences better than 0.0: 0
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