BLASTX 7.6.2
Query= UN08318 /QuerySize=1008
(1007 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O48962|EBP_ARATH Probable 3-beta-hydroxysteroid-Delta(8),Delt... 374 5e-103
sp|Q9FTZ2|EBP_ORYSJ Probable 3-beta-hydroxysteroid-Delta(8),Delt... 274 1e-072
sp|Q60490|EBP_CAVPO 3-beta-hydroxysteroid-Delta(8),Delta(7)-isom... 141 7e-033
sp|P70245|EBP_MOUSE 3-beta-hydroxysteroid-Delta(8),Delta(7)-isom... 139 4e-032
sp|Q9JJ46|EBP_RAT 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomer... 136 4e-031
sp|Q15125|EBP_HUMAN 3-beta-hydroxysteroid-Delta(8),Delta(7)-isom... 132 6e-030
sp|Q9D0P0|EBPL_MOUSE Emopamil-binding protein-like OS=Mus muscul... 110 2e-023
sp|Q9BY08|EBPL_HUMAN Emopamil-binding protein-like OS=Homo sapie... 107 2e-022
>sp|O48962|EBP_ARATH Probable 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
OS=Arabidopsis thaliana GN=At1g20050 PE=2 SV=1
Length = 223
Score = 374 bits (960), Expect = 5e-103
Identities = 180/222 (81%), Positives = 196/222 (88%), Gaps = 4/222 (1%)
Frame = -1
Query: 851 EAAAHPYVPRDLKLPGYVPISMSMSTILAVYLGASLFVVTFVWFLLGRKKAHLDRLLMCW 672
E AHPYVPRDL LPGYVPISMSMS+I+++YLG+SL VV+ VW L GRKKA LD+LLMCW
Sbjct: 2 EELAHPYVPRDLNLPGYVPISMSMSSIVSIYLGSSLLVVSLVWLLFGRKKAKLDKLLMCW 61
Query: 671 WAFTGLTHMVLEGYFVFSPDFFKDNTSCYLAEVWKEYSKGDSRYAGRDSAVIAVEGITAV 492
W FTGLTH++LEGYFVFSP+FFKDNTS YLAEVWKEYSKGDSRY GRDSAV++VEGITAV
Sbjct: 62 WTFTGLTHVILEGYFVFSPEFFKDNTSAYLAEVWKEYSKGDSRYVGRDSAVVSVEGITAV 121
Query: 491 IEGPASLLAVYAIAKGKSYSYVLQLAISLGQLYGCLVYFITAFLEGDNFATNSFYYYSYY 312
I GPASLLA+YAIAK KSYSYVLQLAIS+ QLYGCLVYFITA LEGDNFATNSFYYYSYY
Sbjct: 122 IVGPASLLAIYAIAKEKSYSYVLQLAISVCQLYGCLVYFITAILEGDNFATNSFYYYSYY 181
Query: 311 IFANGWWVLIPFLISYRCWNKICESA----NGVETKIKKKTR 198
I AN WWVLIP LIS+RCW KIC +A N VETK KKKTR
Sbjct: 182 IGANCWWVLIPSLISFRCWKKICAAAAIANNNVETKTKKKTR 223
>sp|Q9FTZ2|EBP_ORYSJ Probable 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
OS=Oryza sativa subsp. japonica GN=Os01g0103600 PE=2 SV=1
Length = 219
Score = 274 bits (699), Expect = 1e-072
Identities = 127/213 (59%), Positives = 158/213 (74%), Gaps = 3/213 (1%)
Frame = -1
Query: 839 HPYVPRDLKLPGYVPISMSMSTILAVYLGASLFVVTFVWFLLGRKKAHL---DRLLMCWW 669
HPY P +L LPG+VP+ +S + IL YL SLF++ VW + GR L DR LMCWW
Sbjct: 7 HPYAPAELHLPGFVPLQLSQAQILVPYLATSLFLLLAVWLISGRCSRRLSDTDRWLMCWW 66
Query: 668 AFTGLTHMVLEGYFVFSPDFFKDNTSCYLAEVWKEYSKGDSRYAGRDSAVIAVEGITAVI 489
AFTGLTH+++EG FVF+P+FF + Y EVWKEYSKGDSRY RD A + VEGITAV+
Sbjct: 67 AFTGLTHIIIEGTFVFAPNFFSNQNPSYFDEVWKEYSKGDSRYVARDPATVTVEGITAVL 126
Query: 488 EGPASLLAVYAIAKGKSYSYVLQLAISLGQLYGCLVYFITAFLEGDNFATNSFYYYSYYI 309
EGPASLLAVYAIA GKSYS++LQ + LGQLYGCLVYFITA+L+G NF T+ FY+++Y+I
Sbjct: 127 EGPASLLAVYAIASGKSYSHILQFTVCLGQLYGCLVYFITAYLDGFNFWTSPFYFWAYFI 186
Query: 308 FANGWWVLIPFLISYRCWNKICESANGVETKIK 210
AN WV+IP +I+ R W KIC + G + K K
Sbjct: 187 GANSSWVVIPTMIAIRSWKKICAAFQGEKVKTK 219
>sp|Q60490|EBP_CAVPO 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase OS=Cavia
porcellus GN=EBP PE=1 SV=3
Length = 229
Score = 141 bits (355), Expect = 7e-033
Identities = 78/217 (35%), Positives = 119/217 (54%), Gaps = 7/217 (3%)
Frame = -1
Query: 839 HPYVPRDLKLPGYVPISMSMSTILAVYLGASLFVVTFVWFLLGRKK----AHLDRLLMCW 672
HPY PR L+L +VP +S I+ V +V +W L R RL +CW
Sbjct: 10 HPYWPRHLRLDHFVPNDLSAWYIVTVLFTVFGALVVTMWLLSSRASVVPLGTWRRLSVCW 69
Query: 671 WAFTGLTHMVLEGYFVFSPDFFKDNTSCYLAEVWKEYSKGDSRYAGRDSAVIAVEGITAV 492
+A H+V+EG+FV + +L+++WKEY+KGDSRY D+ +I +E IT V
Sbjct: 70 FAVCAFVHLVIEGWFVLYQKAILGD-QAFLSQLWKEYAKGDSRYIIEDNFIICMESITVV 128
Query: 491 IEGPASLLAVYAIAKGKSYSYVLQLAISLGQLYGCLVYFITAFLEGDNFAT--NSFYYYS 318
+ GP SL AV A + YVLQ ISLGQ+YG L+YF+T + +G + Y++
Sbjct: 129 LWGPLSLWAVIAFLRQHPSRYVLQFVISLGQIYGDLLYFLTEYRDGFQHGEMGHPIYFWF 188
Query: 317 YYIFANGWWVLIPFLISYRCWNKICESANGVETKIKK 207
Y+ F N W++IP ++ + + + N ++TK+ K
Sbjct: 189 YFFFMNVLWLVIPGVLFFDSVKQFYGAQNALDTKVMK 225
>sp|P70245|EBP_MOUSE 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase OS=Mus
musculus GN=Ebp PE=1 SV=3
Length = 230
Score = 139 bits (349), Expect = 4e-032
Identities = 75/218 (34%), Positives = 122/218 (55%), Gaps = 9/218 (4%)
Frame = -1
Query: 839 HPYVPRDLKLPGYVPISMSMSTILAVYLGASLFVVTFVWFLLGRKK----AHLDRLLMCW 672
HPY PR LKL +VP + S IL S ++ W L R RL +CW
Sbjct: 9 HPYWPRHLKLDNFVPNDLPTSHILVGLFSISGGLIVITWLLSSRASVVPLGAGRRLALCW 68
Query: 671 WAFTGLTHMVLEGYF-VFSPDFFKDNTSCYLAEVWKEYSKGDSRYAGRDSAVIAVEGITA 495
+A H+V+EG+F +++ +D +L+++WKEYSKGDSRY DS V+ +E +TA
Sbjct: 69 FAVCTFIHLVIEGWFSLYNGILLED--QAFLSQLWKEYSKGDSRYILSDSFVVCMETVTA 126
Query: 494 VIEGPASLLAVYAIAKGKSYSYVLQLAISLGQLYGCLVYFITAFLEGDNFAT--NSFYYY 321
+ GP SL V A + + + +VLQL +S+GQ+YG ++YF+T EG + Y++
Sbjct: 127 CLWGPLSLWVVIAFLRQQPFRFVLQLVVSMGQIYGDVLYFLTELHEGLQHGEIGHPVYFW 186
Query: 320 SYYIFANGWWVLIPFLISYRCWNKICESANGVETKIKK 207
Y++F N W++IP ++ + + + +++K+ K
Sbjct: 187 FYFVFLNAVWLVIPSILVLDAIKHLTSAQSVLDSKVMK 224
>sp|Q9JJ46|EBP_RAT 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase OS=Rattus
norvegicus GN=Ebp PE=2 SV=3
Length = 230
Score = 136 bits (340), Expect = 4e-031
Identities = 69/217 (31%), Positives = 118/217 (54%), Gaps = 7/217 (3%)
Frame = -1
Query: 839 HPYVPRDLKLPGYVPISMSMSTILAVYLGASLFVVTFVWFLLGRKK----AHLDRLLMCW 672
HPY PR L+L +VP + IL S ++ W L R RL +CW
Sbjct: 9 HPYWPRHLRLDNFVPNDLPTWHILVGLFSFSGVLIVITWLLSSRVSVVPLGTGRRLALCW 68
Query: 671 WAFTGLTHMVLEGYFVFSPDFFKDNTSCYLAEVWKEYSKGDSRYAGRDSAVIAVEGITAV 492
+A H+V+EG+F F + ++ +L+++WKEYSKGDSRY D ++ +E +TA
Sbjct: 69 FAVCTFIHLVIEGWFSFYHEILLED-QAFLSQLWKEYSKGDSRYILSDGFIVCMESVTAC 127
Query: 491 IEGPASLLAVYAIAKGKSYSYVLQLAISLGQLYGCLVYFITAFLEGDNFAT--NSFYYYS 318
+ GP SL V A + + + +VLQL +S+GQ+YG ++YF+T +G + Y++
Sbjct: 128 LWGPLSLWVVIAFLRHQPFRFVLQLVVSVGQIYGDVLYFLTELRDGFQHGELGHPLYFWF 187
Query: 317 YYIFANGWWVLIPFLISYRCWNKICESANGVETKIKK 207
Y++ N W++IP ++ + + + + ++ K+ K
Sbjct: 188 YFVIMNAIWLVIPGILVFDAIKHLTNAQSMLDNKVMK 224
>sp|Q15125|EBP_HUMAN 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase OS=Homo
sapiens GN=EBP PE=1 SV=3
Length = 230
Score = 132 bits (330), Expect = 6e-030
Identities = 71/219 (32%), Positives = 118/219 (53%), Gaps = 11/219 (5%)
Frame = -1
Query: 839 HPYVPRDLKLPGYVPISMSMSTILAVYLGASLFVVTFVWFLLGRKK----AHLDRLLMCW 672
HPY P+ L+L +VP ILA + +V W L GR RL +CW
Sbjct: 9 HPYWPQHLRLDNFVPNDRPTWHILAGLFSVTGVLVVTTWLLSGRAAVVPLGTWRRLSLCW 68
Query: 671 WAFTGLTHMVLEGYFVFSPDFFKD--NTSCYLAEVWKEYSKGDSRYAGRDSAVIAVEGIT 498
+A G H+V+EG+FV +++D +L+++WKEY+KGDSRY D+ + +E IT
Sbjct: 69 FAVCGFIHLVIEGWFVL---YYEDLLGDQAFLSQLWKEYAKGDSRYILGDNFTVCMETIT 125
Query: 497 AVIEGPASLLAVYAIAKGKSYSYVLQLAISLGQLYGCLVYFITAFLEGDNFAT--NSFYY 324
A + GP SL V A + ++LQL +S+GQ+YG ++YF+T +G + Y+
Sbjct: 126 ACLWGPLSLWVVIAFLRQHPLRFILQLVVSVGQIYGDVLYFLTEHRDGFQHGELGHPLYF 185
Query: 323 YSYYIFANGWWVLIPFLISYRCWNKICESANGVETKIKK 207
+ Y++F N W+++P ++ + + + ++ K K
Sbjct: 186 WFYFVFMNALWLVLPGVLVLDAVKHLTHAQSTLDAKATK 224
>sp|Q9D0P0|EBPL_MOUSE Emopamil-binding protein-like OS=Mus musculus GN=Ebpl PE=2
SV=1
Length = 206
Score = 110 bits (274), Expect = 2e-023
Identities = 59/174 (33%), Positives = 100/174 (57%), Gaps = 4/174 (2%)
Frame = -1
Query: 716 LGRKKAHLDRLLMCWWAFTGLTHMVLEGYFVF-SPDFFKDNTSCYLAEVWKEYSKGDSRY 540
LGR ++ ++R ++ W + L H VLEG FV+ S ++ +A +WKEY K D+R+
Sbjct: 32 LGRGRSAVERWVLAWLCYDSLVHFVLEGAFVYLSIVGNVADSQGLIASLWKEYGKADTRW 91
Query: 539 AGRDSAVIAVEGITAVIEGPASLLAVYAIAKGKSYSYVLQLAISLGQLYGCLVYFITAFL 360
D V+++E +T V++G +L+ +YAI K K Y + +Q+ + + +LYGC + F +L
Sbjct: 92 LYSDPTVVSLEILTVVLDGLLALVLIYAIVKEKYYRHFVQIVLCVCELYGCWMTFFPEWL 151
Query: 359 EGDNFATNS--FYYYSYYIFANGWWVLIPFLISYRCWNKICESANGVETKIKKK 204
G S Y + Y +F NG WVLIP L+ ++ W ++ + + E + KK
Sbjct: 152 VGSPSLNTSSWLYLWVYLVFFNGLWVLIPGLLLWQSWVEL-KKRDSQEANLAKK 204
>sp|Q9BY08|EBPL_HUMAN Emopamil-binding protein-like OS=Homo sapiens GN=EBPL PE=1
SV=1
Length = 206
Score = 107 bits (266), Expect = 2e-022
Identities = 59/173 (34%), Positives = 96/173 (55%), Gaps = 3/173 (1%)
Frame = -1
Query: 716 LGRKKAHLDRLLMCWWAFTGLTHMVLEGYFVF-SPDFFKDNTSCYLAEVWKEYSKGDSRY 540
LGR + DR + W + L H LEG FV+ S N+ +A +WKEY K D+R+
Sbjct: 32 LGRGQGAADRGALIWLCYDALVHFALEGPFVYLSLVGNVANSDGLIASLWKEYGKADARW 91
Query: 539 AGRDSAVIAVEGITAVIEGPASLLAVYAIAKGKSYSYVLQLAISLGQLYGCLVYFITAFL 360
D +++VE +T ++G +L +YAI K K Y + LQ+ + + +LYGC + F+ +L
Sbjct: 92 VYFDPTIVSVEILTVALDGSLALFLIYAIVKEKYYRHFLQITLCVCELYGCWMTFLPEWL 151
Query: 359 -EGDNFATNSFYY-YSYYIFANGWWVLIPFLISYRCWNKICESANGVETKIKK 207
N T+++ Y + Y F NG WVLIP L+ ++ W ++ + + +KK
Sbjct: 152 TRSPNLNTSNWLYCWLYLFFFNGVWVLIPGLLLWQSWLELKKMHQKETSSVKK 204
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,263,552,948
Number of Sequences: 518415
Number of Extensions: 33263552948
Number of Successful Extensions: 238913225
Number of sequences better than 0.0: 0
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