BLASTX 7.6.2
Query= UN08976 /QuerySize=1323
(1322 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q63584|TMEDA_RAT Transmembrane emp24 domain-containing protei... 134 2e-030
sp|Q9D1D4|TMEDA_MOUSE Transmembrane emp24 domain-containing prot... 132 9e-030
sp|O35587|TMEDA_MESAU Transmembrane protein Tmp21 OS=Mesocricetu... 130 3e-029
sp|Q5E971|TMEDA_BOVIN Transmembrane emp24 domain-containing prot... 128 9e-029
sp|Q28735|TMEDA_RABIT Transmembrane emp24 domain-containing prot... 128 9e-029
sp|P49755|TMEDA_HUMAN Transmembrane emp24 domain-containing prot... 127 2e-028
sp|Q5RE32|TMEDA_PONAB Transmembrane emp24 domain-containing prot... 127 3e-028
sp|Q90515|TMEDA_TAKRU Transmembrane emp24 domain-containing prot... 127 3e-028
sp|B3LVB0|TMEDA_DROAN Transmembrane emp24 domain-containing prot... 107 2e-022
sp|Q5A302|TMEDA_CANAL Endoplasmic reticulum vesicle protein 25 O... 107 3e-022
sp|B4JYU5|TMEDA_DROGR Transmembrane emp24 domain-containing prot... 104 3e-021
sp|B4NIY1|TMEDA_DROWI Transmembrane emp24 domain-containing prot... 102 6e-021
sp|B4K4G5|TMEDA_DROMO Transmembrane emp24 domain-containing prot... 102 1e-020
sp|B4GE47|TMEDA_DROPE Transmembrane emp24 domain-containing prot... 101 2e-020
sp|B4MGF8|TMEDA_DROVI Transmembrane emp24 domain-containing prot... 100 3e-020
sp|A0AQ71|TMEDA_DROSI Transmembrane emp24 domain-containing prot... 98 1e-019
sp|B3P6T8|TMEDA_DROER Transmembrane emp24 domain-containing prot... 97 2e-019
sp|Q8SXY6|TMEDA_DROME Transmembrane emp24 domain-containing prot... 97 2e-019
sp|B4PUZ3|TMEDA_DROYA Transmembrane emp24 domain-containing prot... 97 2e-019
sp|Q6BTC2|TMEDA_DEBHA Endoplasmic reticulum vesicle protein 25 O... 88 1e-016
>sp|Q63584|TMEDA_RAT Transmembrane emp24 domain-containing protein 10 OS=Rattus
norvegicus GN=Tmed10 PE=1 SV=2
Length = 219
Score = 134 bits (336), Expect = 2e-030
Identities = 72/207 (34%), Positives = 125/207 (60%), Gaps = 2/207 (0%)
Frame = -1
Query: 1217 PILAAVLFLLTVNHGEAIWLTIP-PTGGTKCVSEEIQSNVVVLADYYVVDEHDPEHTATI 1041
P+L+A+LFL + + ++ P KC+ EEI +++V Y + D+
Sbjct: 13 PLLSALLFLFLLGPSSVLGISFHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRT 72
Query: 1040 SSKVTSPYGNNLHHQDNVTHGQFAFTTQETGNYLACFWVDSSRPQVNPLTLGIDWKIGIA 861
K+T G+ L+ +++ T G+FAFTT++ + CF + + L + +D K G+
Sbjct: 73 HLKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVI-LDMKHGVE 131
Query: 860 AKDWDSVAKKEKIEGVELQLRRLDGLVQSIRENINYIKDREAEMREVSETTNSRVAWFSI 681
AK+++ +AK EK++ +E++LRRL+ L +SI + Y+K RE EMR+ +E+TN+RV +FSI
Sbjct: 132 AKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSI 191
Query: 680 MSLGVCLSVAGSQIWYLKRYFHKKKLI 600
S+ + +A Q++YL+R+F KKLI
Sbjct: 192 FSMFCLIGLATWQVFYLRRFFKAKKLI 218
>sp|Q9D1D4|TMEDA_MOUSE Transmembrane emp24 domain-containing protein 10 OS=Mus
musculus GN=Tmed10 PE=2 SV=1
Length = 219
Score = 132 bits (330), Expect = 9e-030
Identities = 74/214 (34%), Positives = 126/214 (58%), Gaps = 2/214 (0%)
Frame = -1
Query: 1238 GGLVAFSPILAAVLFLLTVNHGEAIWLTIP-PTGGTKCVSEEIQSNVVVLADYYVVDEHD 1062
G L P+ +A LFLL + + ++ P KC+ EEI +++V Y + D+
Sbjct: 6 GPLSRPGPLPSAWLFLLLLGPSSVLGISFHLPVNSRKCLREEIHKDLLVTGAYEITDQSG 65
Query: 1061 PEHTATISSKVTSPYGNNLHHQDNVTHGQFAFTTQETGNYLACFWVDSSRPQVNPLTLGI 882
K+T G+ L+ +++ T G+FAFTT++ + CF + + L + +
Sbjct: 66 GAGGLRTHLKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVI-L 124
Query: 881 DWKIGIAAKDWDSVAKKEKIEGVELQLRRLDGLVQSIRENINYIKDREAEMREVSETTNS 702
D K G+ AK+++ +AK EK++ +E++LRRL+ L +SI + Y+K RE EMR+ +E+TN+
Sbjct: 125 DMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNT 184
Query: 701 RVAWFSIMSLGVCLSVAGSQIWYLKRYFHKKKLI 600
RV +FSI S+ + +A Q++YL+R+F KKLI
Sbjct: 185 RVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLI 218
>sp|O35587|TMEDA_MESAU Transmembrane protein Tmp21 OS=Mesocricetus auratus
GN=TMED10 PE=2 SV=1
Length = 219
Score = 130 bits (325), Expect = 3e-029
Identities = 72/207 (34%), Positives = 123/207 (59%), Gaps = 2/207 (0%)
Frame = -1
Query: 1217 PILAAVLFLLTVNHGEAIWLTIP-PTGGTKCVSEEIQSNVVVLADYYVVDEHDPEHTATI 1041
P A+LFLL + + ++ P KC+ EEI +++V Y + D+
Sbjct: 13 PRPCALLFLLLLGPSSVLAISFHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRT 72
Query: 1040 SSKVTSPYGNNLHHQDNVTHGQFAFTTQETGNYLACFWVDSSRPQVNPLTLGIDWKIGIA 861
K+T G+ L+ +++ T G+FAFTT++ + CF + + L + +D K G+
Sbjct: 73 HLKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVI-LDMKHGVE 131
Query: 860 AKDWDSVAKKEKIEGVELQLRRLDGLVQSIRENINYIKDREAEMREVSETTNSRVAWFSI 681
AK+++ +AK EK++ +E++LRRL+ L +SI + Y+K RE EMR+ +E+TN+RV +FSI
Sbjct: 132 AKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSI 191
Query: 680 MSLGVCLSVAGSQIWYLKRYFHKKKLI 600
S+ + +A Q++YL+R+F KKLI
Sbjct: 192 FSMLCLIGLATWQVFYLRRFFKAKKLI 218
>sp|Q5E971|TMEDA_BOVIN Transmembrane emp24 domain-containing protein 10 OS=Bos
taurus GN=TMED10 PE=2 SV=1
Length = 219
Score = 128 bits (321), Expect = 9e-029
Identities = 71/207 (34%), Positives = 122/207 (58%), Gaps = 2/207 (0%)
Frame = -1
Query: 1217 PILAAVLFLLTVNHGEAIWLTIP-PTGGTKCVSEEIQSNVVVLADYYVVDEHDPEHTATI 1041
P A+L LL + + ++ P KC+ EEI +++V Y + D+
Sbjct: 13 PCPFALLLLLLLGPSSVLAISFHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRT 72
Query: 1040 SSKVTSPYGNNLHHQDNVTHGQFAFTTQETGNYLACFWVDSSRPQVNPLTLGIDWKIGIA 861
K+T G+ L+ +++ T G+FAFTT++ + CF + + L + +D K G+
Sbjct: 73 HLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVI-LDMKHGVE 131
Query: 860 AKDWDSVAKKEKIEGVELQLRRLDGLVQSIRENINYIKDREAEMREVSETTNSRVAWFSI 681
AK+++ +AK EK++ +E++LRRL+ L +SI + Y+K RE EMR+ +E+TN+RV +FSI
Sbjct: 132 AKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSI 191
Query: 680 MSLGVCLSVAGSQIWYLKRYFHKKKLI 600
S+ + +A Q++YL+R+F KKLI
Sbjct: 192 FSMFCLIGLATWQVFYLRRFFKAKKLI 218
>sp|Q28735|TMEDA_RABIT Transmembrane emp24 domain-containing protein 10
OS=Oryctolagus cuniculus GN=TMED10 PE=1 SV=1
Length = 219
Score = 128 bits (321), Expect = 9e-029
Identities = 72/214 (33%), Positives = 124/214 (57%), Gaps = 2/214 (0%)
Frame = -1
Query: 1238 GGLVAFSPILAAVLFLLTVNHGEAIWLTIP-PTGGTKCVSEEIQSNVVVLADYYVVDEHD 1062
G L P A+LFL + + ++ P KC+ EEI +++V Y + D+
Sbjct: 6 GPLARRGPGPLALLFLFLLGPSSVLAISFHLPVNSRKCLREEIHKDLLVTGAYEITDQSG 65
Query: 1061 PEHTATISSKVTSPYGNNLHHQDNVTHGQFAFTTQETGNYLACFWVDSSRPQVNPLTLGI 882
K+T G+ L+ +++ + G+FAFTT++ + CF + + L + +
Sbjct: 66 GAGGLRTHLKITDSAGHILYSKEDASKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVI-L 124
Query: 881 DWKIGIAAKDWDSVAKKEKIEGVELQLRRLDGLVQSIRENINYIKDREAEMREVSETTNS 702
D K G+ AK+++ +AK EK++ +E++LRRL+ L +SI + Y+K RE EMR+ +E+TN+
Sbjct: 125 DMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNT 184
Query: 701 RVAWFSIMSLGVCLSVAGSQIWYLKRYFHKKKLI 600
RV +FSI S+ + +A Q++YL+R+F KKLI
Sbjct: 185 RVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLI 218
>sp|P49755|TMEDA_HUMAN Transmembrane emp24 domain-containing protein 10 OS=Homo
sapiens GN=TMED10 PE=1 SV=2
Length = 219
Score = 127 bits (319), Expect = 2e-028
Identities = 74/209 (35%), Positives = 123/209 (58%), Gaps = 8/209 (3%)
Frame = -1
Query: 1217 PILAAVLFLLTVNHGEAIWLTIP---PTGGTKCVSEEIQSNVVVLADYYVVDEHDPEHTA 1047
P+ +LFLL G + L I P KC+ EEI +++V Y + D+
Sbjct: 15 PLALLLLFLL----GPRLVLAISFHLPINSRKCLREEIHKDLLVTGAYEISDQSGGAGGL 70
Query: 1046 TISSKVTSPYGNNLHHQDNVTHGQFAFTTQETGNYLACFWVDSSRPQVNPLTLGIDWKIG 867
K+T G+ L+ +++ T G+FAFTT++ + CF + + L + +D K G
Sbjct: 71 RSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVI-LDMKHG 129
Query: 866 IAAKDWDSVAKKEKIEGVELQLRRLDGLVQSIRENINYIKDREAEMREVSETTNSRVAWF 687
+ AK+++ +AK EK++ +E++LRRL+ L +SI + Y+K RE EMR+ +E+TN+RV +F
Sbjct: 130 VEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYF 189
Query: 686 SIMSLGVCLSVAGSQIWYLKRYFHKKKLI 600
SI S+ + +A Q++YL+R+F KKLI
Sbjct: 190 SIFSMFCLIGLATWQVFYLRRFFKAKKLI 218
>sp|Q5RE32|TMEDA_PONAB Transmembrane emp24 domain-containing protein 10 OS=Pongo
abelii GN=TMED10 PE=2 SV=1
Length = 219
Score = 127 bits (317), Expect = 3e-028
Identities = 73/209 (34%), Positives = 124/209 (59%), Gaps = 8/209 (3%)
Frame = -1
Query: 1217 PILAAVLFLLTVNHGEAIWLTIP---PTGGTKCVSEEIQSNVVVLADYYVVDEHDPEHTA 1047
P+ +LFLL G ++ L I P KC+ EEI +++V Y + D+
Sbjct: 15 PLALLLLFLL----GPSLVLAISFHLPINSRKCLREEIHKDLLVTGAYEISDQSGGAGGL 70
Query: 1046 TISSKVTSPYGNNLHHQDNVTHGQFAFTTQETGNYLACFWVDSSRPQVNPLTLGIDWKIG 867
K+T G+ L+ +++ T G+FAFTT++ + CF + + L + +D K G
Sbjct: 71 RSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVI-LDMKHG 129
Query: 866 IAAKDWDSVAKKEKIEGVELQLRRLDGLVQSIRENINYIKDREAEMREVSETTNSRVAWF 687
+ AK+++ +AK EK++ +E++LRRL+ L +SI + Y++ RE EMR+ +E+TN+RV +F
Sbjct: 130 VEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMEKREEEMRDTNESTNTRVLYF 189
Query: 686 SIMSLGVCLSVAGSQIWYLKRYFHKKKLI 600
SI S+ + +A Q++YL+R+F KKLI
Sbjct: 190 SIFSMFCLIGLATWQVFYLRRFFKAKKLI 218
>sp|Q90515|TMEDA_TAKRU Transmembrane emp24 domain-containing protein 10
OS=Takifugu rubripes GN=tmed10 PE=3 SV=1
Length = 213
Score = 127 bits (317), Expect = 3e-028
Identities = 72/210 (34%), Positives = 122/210 (58%), Gaps = 7/210 (3%)
Frame = -1
Query: 1211 LAAVLFLLTVNHGEAIWLTIPPTGGTKCVSEEIQSNVVVLADYYVVDEHDPEHTATI--- 1041
L A+LFL + P KC+ EEI +V+V +Y + ++ HT++
Sbjct: 4 LTALLFLPVLIESAFSISFFLPVNTRKCLREEIHKDVLVTGEYEISEQVVTVHTSSTVVG 63
Query: 1040 ---SSKVTSPYGNNLHHQDNVTHGQFAFTTQETGNYLACFWVDSSRPQVNPLTLGIDWKI 870
K+T + L+ +++ T G+FAFTT++ + CF +V + +D K
Sbjct: 64 DGSIFKITDSSSHTLYSKEDATKGKFAFTTEDYDMFEVCF-ESKCTGRVPDQLVNLDMKH 122
Query: 869 GIAAKDWDSVAKKEKIEGVELQLRRLDGLVQSIRENINYIKDREAEMREVSETTNSRVAW 690
G+ AK+++ +AK EK++ +E++LRRL+ L +SI + Y+K RE EMR+ +E+TN+RV +
Sbjct: 123 GVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLY 182
Query: 689 FSIMSLGVCLSVAGSQIWYLKRYFHKKKLI 600
FSI S+ + +A Q++YL+R+F KKLI
Sbjct: 183 FSIFSMFCLIGLATWQVFYLRRFFKAKKLI 212
>sp|B3LVB0|TMEDA_DROAN Transmembrane emp24 domain-containing protein bai
OS=Drosophila ananassae GN=bai PE=3 SV=1
Length = 206
Score = 107 bits (267), Expect = 2e-022
Identities = 66/194 (34%), Positives = 108/194 (55%), Gaps = 8/194 (4%)
Frame = -1
Query: 1175 GEAIWLTIPPTGGTKCVSEEIQSNVVVLADYYVVDEHDPEHTATISSKVTSPYGNNLHHQ 996
GEA+ + P KC+ E+IQ+N +V+ +Y V D P ++ T G+ L Q
Sbjct: 18 GEAVMFKLTP-NTQKCLKEDIQANQLVIGEYEVSDV--PGQVIDYIARDTK--GHILSQQ 72
Query: 995 DNVTHGQFAFTTQETGNYLACFWVDSSRPQVN--PLTLGIDWKIGIAAKDWDSVAKKEKI 822
+++T G+F+F ++ Y CF + P P + + K G+ K ++ + + K+
Sbjct: 73 EHITKGKFSFMSEVYDAYEICF-ISKVPPHQRGIPQEVSLSTKKGVETKSYEGIGEASKL 131
Query: 821 EGVELQLRRLDGLVQSIRENINYIKDREAEMREVSETTNSRVAWFSIMSLGVCLSVAGSQ 642
+ +E+ L+RL+ L SI + ++ RE EMR+ +E TNSRV +FSI S+ L +A Q
Sbjct: 132 KPLEVDLKRLEDLSDSIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQ 191
Query: 641 IWYLKRYFHKKKLI 600
+ YL+RYF KKLI
Sbjct: 192 VLYLRRYFKAKKLI 205
>sp|Q5A302|TMEDA_CANAL Endoplasmic reticulum vesicle protein 25 OS=Candida
albicans GN=ERV25 PE=3 SV=1
Length = 215
Score = 107 bits (265), Expect = 3e-022
Identities = 67/212 (31%), Positives = 112/212 (52%), Gaps = 15/212 (7%)
Frame = -1
Query: 1205 AVLFLLTVNHGEAIWLTIP--PTGGTKCVSEEIQSNVVVLADYYVVDEHDPEHTATISSK 1032
A++F L V+ + L +P P C+ + +Q N +V+ + + + + K
Sbjct: 9 ALVFSLFVSSAIGLHLEVPALPNPQPVCIRDFVQENQMVVVN--IKTDGSKGDGQRLDLK 66
Query: 1031 VTSPYGNNLHH-QDNVTHGQFAFTTQETG-------NYLACFWVDSSRPQVNPLTLGIDW 876
VT GN + +D V H AFT+Q NYL W S+ Q ++ +D
Sbjct: 67 VTDSLGNEYRNKKDVVGHANVAFTSQHNAAIDICLTNYLDNKW---SKHQQTVRSVELDI 123
Query: 875 KIGIAAKDWDSVAKKEKIEGVELQLRRLDGLVQSIRENINYIKDREAEMREVSETTNSRV 696
+ G AA+DW+++ EK++ VE++L+R++ + + I E + Y+K RE MR+ +E+TNSRV
Sbjct: 124 ESGAAARDWNALQASEKLKPVEVELKRIESITEEIVEELRYLKAREERMRDTNESTNSRV 183
Query: 695 AWFSIMSLGVCLSVAGSQIWYLKRYFHKKKLI 600
WFSI+ + + QI YL+ YF K +I
Sbjct: 184 KWFSIVVIASLVGFGVWQIQYLRHYFKVKHII 215
>sp|B4JYU5|TMEDA_DROGR Transmembrane emp24 domain-containing protein bai
OS=Drosophila grimshawi GN=bai PE=3 SV=2
Length = 206
Score = 104 bits (257), Expect = 3e-021
Identities = 67/195 (34%), Positives = 111/195 (56%), Gaps = 10/195 (5%)
Frame = -1
Query: 1178 HGEAIWLTIPPTGGTKCVSEEIQSNVVVLADYYVVDEHDPEHTATISSKVTSPYGNNLHH 999
HG LT P T KC+ E+IQ+N +V+ +Y V D P ++ T G+ L
Sbjct: 19 HGVMFHLT-PNT--QKCLKEDIQANQLVMGEYEVSDV--PGQIIDYIARDTK--GHILSQ 71
Query: 998 QDNVTHGQFAFTTQETGNYLACFWVDSSRPQVNPLT--LGIDWKIGIAAKDWDSVAKKEK 825
++++T G+F+FT++ Y CF + P ++ + + K G+ K+++ + + K
Sbjct: 72 KEHITKGKFSFTSEVFDAYEICF-ISKVPPHQRGISQEVSLVTKKGVETKNYEGIGEASK 130
Query: 824 IEGVELQLRRLDGLVQSIRENINYIKDREAEMREVSETTNSRVAWFSIMSLGVCLSVAGS 645
++ +E+ L+RL+ L SI + ++ RE EMR+ +E TNSRV +FSI S+ L +A
Sbjct: 131 LKPLEVDLKRLEDLSDSIVRDFAVMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATW 190
Query: 644 QIWYLKRYFHKKKLI 600
Q+ YL+RYF KKLI
Sbjct: 191 QVLYLRRYFKAKKLI 205
>sp|B4NIY1|TMEDA_DROWI Transmembrane emp24 domain-containing protein bai
OS=Drosophila willistoni GN=bai PE=3 SV=1
Length = 206
Score = 102 bits (254), Expect = 6e-021
Identities = 64/207 (30%), Positives = 112/207 (54%), Gaps = 8/207 (3%)
Frame = -1
Query: 1214 ILAAVLFLLTVNHGEAIWLTIPPTGGTKCVSEEIQSNVVVLADYYVVDEHDPEHTATISS 1035
ILA + + G+++ + P KC+ E+IQ+N +V+ +Y V D I
Sbjct: 5 ILATLAIFGCIWPGQSVMFHLTP-NTQKCLKEDIQANQMVMGEYEVSDVPG----QVIDF 59
Query: 1034 KVTSPYGNNLHHQDNVTHGQFAFTTQETGNYLACFWVDSSRPQVNPLT--LGIDWKIGIA 861
V G+ L ++++T +F+F ++ +Y CF + P + + + K G+
Sbjct: 60 IVRDTKGHILSQKEHITKAKFSFMSEVYDSYEICF-ISKVPPHQRGIAQQVALTTKKGVE 118
Query: 860 AKDWDSVAKKEKIEGVELQLRRLDGLVQSIRENINYIKDREAEMREVSETTNSRVAWFSI 681
K+++ + + K++ +E+ L+RL+ L SI + ++ RE EMR+ +E TNSRV +FSI
Sbjct: 119 TKNYEGIGEASKLKPLEVDLKRLEDLSDSIVRDFVMMRKREEEMRDTNEKTNSRVLFFSI 178
Query: 680 MSLGVCLSVAGSQIWYLKRYFHKKKLI 600
S+ L +A Q+ YL+RYF KKLI
Sbjct: 179 FSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|B4K4G5|TMEDA_DROMO Transmembrane emp24 domain-containing protein bai
OS=Drosophila mojavensis GN=bai PE=3 SV=1
Length = 206
Score = 102 bits (252), Expect = 1e-020
Identities = 61/185 (32%), Positives = 104/185 (56%), Gaps = 7/185 (3%)
Frame = -1
Query: 1148 PTGGTKCVSEEIQSNVVVLADYYVVDEHDPEHTATISSKVTSPYGNNLHHQDNVTHGQFA 969
P KC+ E+IQ+N +V+ +Y V D P ++ T G+ L ++++T G+F+
Sbjct: 26 PPNTQKCLKEDIQANQLVMGEYEVSDV--PGQVIDYIARDTK--GHILSQKEHITKGKFS 81
Query: 968 FTTQETGNYLACFWVDSSRPQVNPLT--LGIDWKIGIAAKDWDSVAKKEKIEGVELQLRR 795
F ++ Y CF + P ++ + + K G+ K ++ + + K++ +E+ L+R
Sbjct: 82 FMSEVYDAYEICF-ISKVPPHQRGISQEVSLVTKKGVETKSYEGIGEASKLKPLEVDLKR 140
Query: 794 LDGLVQSIRENINYIKDREAEMREVSETTNSRVAWFSIMSLGVCLSVAGSQIWYLKRYFH 615
L+ L SI + ++ RE EMR+ +E TNSRV +FSI S+ L +A Q+ YL+RYF
Sbjct: 141 LEDLSDSIVRDFALMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFK 200
Query: 614 KKKLI 600
KKLI
Sbjct: 201 AKKLI 205
>sp|B4GE47|TMEDA_DROPE Transmembrane emp24 domain-containing protein bai
OS=Drosophila persimilis GN=bai PE=3 SV=1
Length = 206
Score = 101 bits (250), Expect = 2e-020
Identities = 61/180 (33%), Positives = 102/180 (56%), Gaps = 7/180 (3%)
Frame = -1
Query: 1133 KCVSEEIQSNVVVLADYYVVDEHDPEHTATISSKVTSPYGNNLHHQDNVTHGQFAFTTQE 954
KC+ E+IQ+N +V+ +Y V D P ++ T G+ L ++++T G+F+F ++
Sbjct: 31 KCLKEDIQANQLVMGEYEVSDV--PGQIIDYVARDTK--GHILSQKEHITKGKFSFMSEV 86
Query: 953 TGNYLACFWVDSSRPQVN--PLTLGIDWKIGIAAKDWDSVAKKEKIEGVELQLRRLDGLV 780
Y CF + P P + + K G+ K ++ + + K++ +E+ L+RL+ L
Sbjct: 87 YDAYEICF-ISKVPPHQRGIPQEVSLVTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLS 145
Query: 779 QSIRENINYIKDREAEMREVSETTNSRVAWFSIMSLGVCLSVAGSQIWYLKRYFHKKKLI 600
SI + ++ RE EMR+ +E TNSRV +FSI S+ L +A Q+ YL+RYF KKLI
Sbjct: 146 DSIVRDFILMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|B4MGF8|TMEDA_DROVI Transmembrane emp24 domain-containing protein bai
OS=Drosophila virilis GN=bai PE=3 SV=1
Length = 206
Score = 100 bits (248), Expect = 3e-020
Identities = 60/180 (33%), Positives = 103/180 (57%), Gaps = 7/180 (3%)
Frame = -1
Query: 1133 KCVSEEIQSNVVVLADYYVVDEHDPEHTATISSKVTSPYGNNLHHQDNVTHGQFAFTTQE 954
KC+ E+IQ+N +V+ +Y V D P ++ T G+ L ++++T G+F+F ++
Sbjct: 31 KCLKEDIQANQLVMGEYEVSDV--PGQIIDYIARDTK--GHILSQKEHITKGKFSFMSEV 86
Query: 953 TGNYLACFWVDSSRPQVNPLT--LGIDWKIGIAAKDWDSVAKKEKIEGVELQLRRLDGLV 780
Y CF + P ++ + + K G+ K ++ + + K++ +E+ L+RL+ L
Sbjct: 87 YDAYEICF-ISKVPPHQRGISQEVSLVTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLS 145
Query: 779 QSIRENINYIKDREAEMREVSETTNSRVAWFSIMSLGVCLSVAGSQIWYLKRYFHKKKLI 600
SI + ++ RE EMR+ +E TNSRV +FSI S+ L +A Q+ YL+RYF KKLI
Sbjct: 146 DSIVRDFALMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|A0AQ71|TMEDA_DROSI Transmembrane emp24 domain-containing protein bai
OS=Drosophila simulans GN=bai PE=3 SV=1
Length = 206
Score = 98 bits (243), Expect = 1e-019
Identities = 60/179 (33%), Positives = 101/179 (56%), Gaps = 5/179 (2%)
Frame = -1
Query: 1133 KCVSEEIQSNVVVLADYYVVDEHDPEHTATISSKVTSPYGNNLHHQDNVTHGQFAFTTQE 954
KC+ E+IQ+N +V+ +Y V D P ++ T G+ L ++++T G+F+F ++
Sbjct: 31 KCLKEDIQANQLVMGEYEVSDV--PGQIIDYIARDTK--GHILSQKEHITKGKFSFMSEV 86
Query: 953 TGNYLACFWVDSSRPQVNPL-TLGIDWKIGIAAKDWDSVAKKEKIEGVELQLRRLDGLVQ 777
Y CF Q + + + K G+ K ++ + + K++ +E+ L+RL+ L
Sbjct: 87 YETYEICFISKVPAHQRGVVQEVSLLTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLSD 146
Query: 776 SIRENINYIKDREAEMREVSETTNSRVAWFSIMSLGVCLSVAGSQIWYLKRYFHKKKLI 600
SI + ++ RE EMR+ +E TNSRV +FSI S+ L +A Q+ YL+RYF KKLI
Sbjct: 147 SIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|B3P6T8|TMEDA_DROER Transmembrane emp24 domain-containing protein bai
OS=Drosophila erecta GN=bai PE=3 SV=1
Length = 206
Score = 97 bits (241), Expect = 2e-019
Identities = 60/179 (33%), Positives = 101/179 (56%), Gaps = 5/179 (2%)
Frame = -1
Query: 1133 KCVSEEIQSNVVVLADYYVVDEHDPEHTATISSKVTSPYGNNLHHQDNVTHGQFAFTTQE 954
KC+ E+IQ+N +V+ +Y V D P ++ T G+ L ++++T G+F+F ++
Sbjct: 31 KCLKEDIQANQLVMGEYEVSDV--PGQIIDYIARDTK--GHILSQKEHITKGKFSFMSEV 86
Query: 953 TGNYLACFWVDSSRPQVNPL-TLGIDWKIGIAAKDWDSVAKKEKIEGVELQLRRLDGLVQ 777
Y CF Q + + + K G+ K ++ + + K++ +E+ L+RL+ L
Sbjct: 87 YDAYEICFISKVPAHQRGIVQEVSLLTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLSD 146
Query: 776 SIRENINYIKDREAEMREVSETTNSRVAWFSIMSLGVCLSVAGSQIWYLKRYFHKKKLI 600
SI + ++ RE EMR+ +E TNSRV +FSI S+ L +A Q+ YL+RYF KKLI
Sbjct: 147 SIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|Q8SXY6|TMEDA_DROME Transmembrane emp24 domain-containing protein bai
OS=Drosophila melanogaster GN=bai PE=2 SV=1
Length = 206
Score = 97 bits (241), Expect = 2e-019
Identities = 59/179 (32%), Positives = 101/179 (56%), Gaps = 5/179 (2%)
Frame = -1
Query: 1133 KCVSEEIQSNVVVLADYYVVDEHDPEHTATISSKVTSPYGNNLHHQDNVTHGQFAFTTQE 954
KC+ E+IQ+N +V+ ++ V D P ++ T G+ L ++++T G+F+F ++
Sbjct: 31 KCLKEDIQANQLVMGEFEVSDV--PGQIIDYIARDTK--GHILSQKEHITKGKFSFMSEV 86
Query: 953 TGNYLACFWVDSSRPQVNPL-TLGIDWKIGIAAKDWDSVAKKEKIEGVELQLRRLDGLVQ 777
Y CF Q + + + K G+ K ++ + + K++ +E+ L+RL+ L
Sbjct: 87 YDTYEICFISKVPAHQRGVIQEVSLLTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLSD 146
Query: 776 SIRENINYIKDREAEMREVSETTNSRVAWFSIMSLGVCLSVAGSQIWYLKRYFHKKKLI 600
SI + ++ RE EMR+ +E TNSRV +FSI S+ L +A Q+ YL+RYF KKLI
Sbjct: 147 SIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|B4PUZ3|TMEDA_DROYA Transmembrane emp24 domain-containing protein bai
OS=Drosophila yakuba GN=bai PE=3 SV=1
Length = 206
Score = 97 bits (241), Expect = 2e-019
Identities = 60/179 (33%), Positives = 101/179 (56%), Gaps = 5/179 (2%)
Frame = -1
Query: 1133 KCVSEEIQSNVVVLADYYVVDEHDPEHTATISSKVTSPYGNNLHHQDNVTHGQFAFTTQE 954
KC+ E+IQ+N +V+ +Y V D P ++ T G+ L ++++T G+F+F ++
Sbjct: 31 KCLKEDIQANQLVMGEYEVSDV--PGQIIDYIARDTK--GHILSQKEHITKGKFSFMSEV 86
Query: 953 TGNYLACFWVDSSRPQVNPL-TLGIDWKIGIAAKDWDSVAKKEKIEGVELQLRRLDGLVQ 777
Y CF Q + + + K G+ K ++ + + K++ +E+ L+RL+ L
Sbjct: 87 YDAYEICFISKVPAHQRGIVQEVSLLTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLSD 146
Query: 776 SIRENINYIKDREAEMREVSETTNSRVAWFSIMSLGVCLSVAGSQIWYLKRYFHKKKLI 600
SI + ++ RE EMR+ +E TNSRV +FSI S+ L +A Q+ YL+RYF KKLI
Sbjct: 147 SIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLI 205
>sp|Q6BTC2|TMEDA_DEBHA Endoplasmic reticulum vesicle protein 25 OS=Debaryomyces
hansenii GN=ERV25 PE=3 SV=2
Length = 214
Score = 88 bits (217), Expect = 1e-016
Identities = 55/213 (25%), Positives = 106/213 (49%), Gaps = 11/213 (5%)
Frame = -1
Query: 1211 LAAVLFLLT--VNHGEAIWLTIPPTGGTK--CVSEEIQSNVVVLADYYVVDEHDPEHTAT 1044
++ +LF+++ ++ A+ L IP T C+ + +Q +V+ + + +
Sbjct: 4 ISTLLFIISTFISLVSALQLAIPATTNPDPFCIRDFVQEEQMVVVN--IKTNGNSGDGQR 61
Query: 1043 ISSKVTSPYGNNLHHQDNVTHG-QFAFTTQETGNYLACFWVDSSRPQVNPLT----LGID 879
+ ++ GN ++++ + FT+ + + CF R + +D
Sbjct: 62 LDLRIVDSLGNEYRRKNDIAGSVKIGFTSHNSAAFDICFTNQLERKWSKNTNFVREIELD 121
Query: 878 WKIGIAAKDWDSVAKKEKIEGVELQLRRLDGLVQSIRENINYIKDREAEMREVSETTNSR 699
+ G AA+DW++V EK++ VE+ LRR++ I + Y+K RE MR+ +E+TNSR
Sbjct: 122 VESGAAARDWNAVQAAEKLKPVEVDLRRIEETTYEISGELQYLKAREERMRDTNESTNSR 181
Query: 698 VAWFSIMSLGVCLSVAGSQIWYLKRYFHKKKLI 600
V WFSI+ + + + Q+ YL+ YF K +I
Sbjct: 182 VKWFSILVITSLVGLGAWQVQYLRHYFKVKHII 214
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,801,685,782
Number of Sequences: 518415
Number of Extensions: 36801685782
Number of Successful Extensions: 258262551
Number of sequences better than 0.0: 0
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