BLASTX 7.6.2
Query= UN09098 /QuerySize=980
(979 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9ASX2|TRNH1_ARATH Tropinone reductase homolog At1g07440 OS=A... 372 2e-102
sp|P50165|TRNH_DATST Tropinone reductase homolog OS=Datura stram... 288 6e-077
sp|P50162|TRN1_DATST Tropinone reductase 1 OS=Datura stramonium ... 284 9e-076
sp|P50163|TRN2_DATST Tropinone reductase 2 OS=Datura stramonium ... 273 1e-072
sp|P50164|TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamus niger G... 271 8e-072
sp|Q8SPU8|DHRS4_BOVIN Dehydrogenase/reductase SDR family member ... 131 1e-029
sp|P50842|KDUD_BACSU 2-dehydro-3-deoxy-D-gluconate 5-dehydrogena... 127 1e-028
sp|P50199|GNO_GLUOX Gluconate 5-dehydrogenase OS=Gluconobacter o... 126 2e-028
sp|Q9BTZ2|DHRS4_HUMAN Dehydrogenase/reductase SDR family member ... 124 1e-027
sp|Q5RCF8|DHRS4_PONAB Dehydrogenase/reductase SDR family member ... 124 1e-027
sp|Q9GKX2|DHRS4_RABIT Dehydrogenase/reductase SDR family member ... 123 2e-027
sp|P0A9Q0|IDNO_ECOL6 Gluconate 5-dehydrogenase OS=Escherichia co... 120 2e-026
sp|P0A9P9|IDNO_ECOLI Gluconate 5-dehydrogenase OS=Escherichia co... 120 2e-026
sp|Q99LB2|DHRS4_MOUSE Dehydrogenase/reductase SDR family member ... 116 3e-025
sp|Q13268|DHRS2_HUMAN Dehydrogenase/reductase SDR family member ... 115 7e-025
sp|Q8VID1|DHRS4_RAT Dehydrogenase/reductase SDR family member 4 ... 114 9e-025
sp|Q8GAV9|CPNA_COMS9 Cyclopentanol dehydrogenase OS=Comamonas sp... 111 1e-023
sp|Q937L4|CPNA_COMTE Cyclopentanol dehydrogenase OS=Comamonas te... 111 1e-023
sp|P76633|YGCW_ECOLI Uncharacterized oxidoreductase ygcW OS=Esch... 100 2e-020
sp|P71079|FABL_BACSU Enoyl-[acyl-carrier-protein] reductase [NAD... 96 3e-019
>sp|Q9ASX2|TRNH1_ARATH Tropinone reductase homolog At1g07440 OS=Arabidopsis
thaliana GN=At1g07440 PE=1 SV=1
Length = 266
Score = 372 bits (955), Expect = 2e-102
Identities = 186/262 (70%), Positives = 214/262 (81%), Gaps = 1/262 (0%)
Frame = +2
Query: 41 KMDKRWSLEGTTALVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKKKGFQ 220
+ +RWSL+ T LVTGG GIGHAIVEE AGFG +H C +E LN+ L +W+KKGFQ
Sbjct: 5 EQSQRWSLKAKTVLVTGGTKGIGHAIVEEFAGFGAVIHTCARNEYELNECLSKWQKKGFQ 64
Query: 221 VSGSVCDVSSRSEREKLMQTVSTMFNGKLNILVNNVASARVKPTTEYHEDDFSFHISTNL 400
V+GSVCD S R EREKLMQTVS+MF GKL+IL+NN+ + R KPT +Y +DFSFHISTNL
Sbjct: 65 VTGSVCDASLRPEREKLMQTVSSMFGGKLDILINNLGAIRSKPTLDYTAEDFSFHISTNL 124
Query: 401 ESAYHLSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACEWAK 580
ESAYHLSQL+HP LKAS G+I+F+SSIAG+VS + GS+YS TKGALNQLARNLACEWA
Sbjct: 125 ESAYHLSQLAHPLLKASGCGNIIFMSSIAGVVSASVGSIYSATKGALNQLARNLACEWAS 184
Query: 581 DGIRANAVAPNFIYTALAKPFLDDAGFNKSLSSRTPLGRPGEPKEVASLVAFLCLPAASY 760
DGIRANAVAP I T LA+ DD F K + SR PLGR GEP+EV+SLVAFLC+PAASY
Sbjct: 185 DGIRANAVAPAVIATPLAEAVYDDE-FKKVVISRKPLGRFGEPEEVSSLVAFLCMPAASY 243
Query: 761 ITGQTICVDGGLTVNGFSYQPQ 826
ITGQTICVDGGLTVNGFSYQPQ
Sbjct: 244 ITGQTICVDGGLTVNGFSYQPQ 265
>sp|P50165|TRNH_DATST Tropinone reductase homolog OS=Datura stramonium PE=2
SV=1
Length = 268
Score = 288 bits (735), Expect = 6e-077
Identities = 142/258 (55%), Positives = 188/258 (72%), Gaps = 3/258 (1%)
Frame = +2
Query: 47 DKRWSLEGTTALVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKKKGFQVS 226
D+RWSL G TALVTGG GIG+AIVEELA FG +V+ C S+ L++ L +W++KGF+VS
Sbjct: 10 DRRWSLRGMTALVTGGTRGIGYAIVEELANFGAEVYTCSRSQNDLDECLEKWRRKGFKVS 69
Query: 227 GSVCDVSSRSEREKLMQTVSTMFNGKLNILVNNVASARVKPTTEYHEDDFSFHISTNLES 406
G VCDVSS S+R+ LM++V++ FNGKLNIL+NN + K T + +D+S + TN E+
Sbjct: 70 GPVCDVSSISQRQTLMESVTSSFNGKLNILINNAGTTIPKEATNFTAEDYSIIMGTNFEA 129
Query: 407 AYHLSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACEWAKDG 586
+Y+L QL+HP LKAS + SIVF SS AG++++ S+Y+ +KGA+NQ+ ++LACEWAKD
Sbjct: 130 SYNLCQLAHPLLKASGNASIVFNSSAAGVIAVPLSSIYAASKGAINQVTKSLACEWAKDS 189
Query: 587 IRANAVAPNFIYTALAKPFLDDAGFNKSLSS---RTPLGRPGEPKEVASLVAFLCLPAAS 757
IR NAVAP I T + + K++ S R P+ R GEP EV+SLV +LCLP AS
Sbjct: 190 IRVNAVAPWIINTPIIEAACQVPSQKKNIESLIGRAPMKRAGEPSEVSSLVTYLCLPTAS 249
Query: 758 YITGQTICVDGGLTVNGF 811
YITGQ ICVDGG TVNGF
Sbjct: 250 YITGQIICVDGGYTVNGF 267
>sp|P50162|TRN1_DATST Tropinone reductase 1 OS=Datura stramonium GN=TR1 PE=1
SV=1
Length = 273
Score = 284 bits (725), Expect = 9e-076
Identities = 139/264 (52%), Positives = 192/264 (72%), Gaps = 4/264 (1%)
Frame = +2
Query: 29 VINQKMDKRWSLEGTTALVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKK 208
++N + RWSL+GTTALVTGG+ GIG+AIVEELAG G +V+ C +E L++ L W++
Sbjct: 8 MMNCNNEGRWSLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWRE 67
Query: 209 KGFQVSGSVCDVSSRSEREKLMQTVSTMFNGKLNILVNNVASARVKPTTEYHEDDFSFHI 388
KG V GSVCD+ SR+ER+KLMQTV+ +F+GKLNILVNN K ++ E D++ +
Sbjct: 68 KGLNVEGSVCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIM 127
Query: 389 STNLESAYHLSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLAC 568
TN E+AYHLSQ+++P LKAS++G+++F+SSIAG ++ S+YS +KGA+NQ+ ++LAC
Sbjct: 128 GTNFEAAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLAC 187
Query: 569 EWAKDGIRANAVAPNFIYTALAKPFLDDAGFNK----SLSSRTPLGRPGEPKEVASLVAF 736
EWAKD IR N+VAP I T L + + K + +TP+GR G+P+EV++L+AF
Sbjct: 188 EWAKDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAF 247
Query: 737 LCLPAASYITGQTICVDGGLTVNG 808
LC PAASYITGQ I DGG T NG
Sbjct: 248 LCFPAASYITGQIIWADGGFTANG 271
>sp|P50163|TRN2_DATST Tropinone reductase 2 OS=Datura stramonium GN=TR2 PE=1
SV=1
Length = 260
Score = 273 bits (698), Expect = 1e-072
Identities = 139/257 (54%), Positives = 180/257 (70%), Gaps = 3/257 (1%)
Frame = +2
Query: 44 MDKRWSLEGTTALVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKKKGFQV 223
M RW+LEG TALVTGG+ GIG+ IVEELA G V+ C ++ LN L +W+ KGF+V
Sbjct: 1 MAGRWNLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKV 60
Query: 224 SGSVCDVSSRSEREKLMQTVSTMFNGKLNILVNNVASARVKPTTEYHEDDFSFHISTNLE 403
SVCD+SSRSER++LM TV+ F+GKLNILVNN K +Y +D+S +S N E
Sbjct: 61 EASVCDLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFE 120
Query: 404 SAYHLSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACEWAKD 583
+AYHLS L+HPFLKASE G++VFISS++G +++ ++Y TKGA++QL R LA EWAKD
Sbjct: 121 AAYHLSVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAKD 180
Query: 584 GIRANAVAPNFIYTALAKPFLDDAGFNKSLS---SRTPLGRPGEPKEVASLVAFLCLPAA 754
IR N V P I T+L + + D ++L+ R L R GEPKE+A++VAFLC PAA
Sbjct: 181 NIRVNGVGPGVIATSLVEMTIQDPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCFPAA 240
Query: 755 SYITGQTICVDGGLTVN 805
SY+TGQ I VDGGL N
Sbjct: 241 SYVTGQIIYVDGGLMAN 257
>sp|P50164|TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamus niger GN=TR2 PE=2
SV=1
Length = 260
Score = 271 bits (691), Expect = 8e-072
Identities = 139/258 (53%), Positives = 178/258 (68%), Gaps = 3/258 (1%)
Frame = +2
Query: 44 MDKRWSLEGTTALVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKKKGFQV 223
M RW+LEG TALVTGG+ GIG+ IVEELA G V+ C ++ L++ L +W+ KGF V
Sbjct: 1 MAGRWNLEGCTALVTGGSRGIGYGIVEELANLGASVYTCSRNQKELDECLTQWRSKGFNV 60
Query: 224 SGSVCDVSSRSEREKLMQTVSTMFNGKLNILVNNVASARVKPTTEYHEDDFSFHISTNLE 403
SVCD+SSRSERE+ M+TVS F+GKLNILVNN K +Y +D+S +S N E
Sbjct: 61 EASVCDLSSRSEREEFMKTVSNHFHGKLNILVNNAGIVIYKEAKDYTMEDYSHIMSINFE 120
Query: 404 SAYHLSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACEWAKD 583
+AYHLS L+HPFLKASE G++VFISSI+G ++ ++Y TKGA++QL R LA EWAKD
Sbjct: 121 AAYHLSVLAHPFLKASERGNVVFISSISGASALPYEAVYGATKGAMDQLTRCLAFEWAKD 180
Query: 584 GIRANAVAPNFIYTALAKPFLDDAGFNKSLS---SRTPLGRPGEPKEVASLVAFLCLPAA 754
IR N V P I T++ + + D ++L R L R GEPKE+A++VAFLC PAA
Sbjct: 181 NIRVNGVGPGVIATSMVEMTIQDPEQKENLDKLIDRCALRRMGEPKELAAVVAFLCFPAA 240
Query: 755 SYITGQTICVDGGLTVNG 808
SY+TGQ I VDGG NG
Sbjct: 241 SYVTGQIIYVDGGFMANG 258
>sp|Q8SPU8|DHRS4_BOVIN Dehydrogenase/reductase SDR family member 4 OS=Bos taurus
GN=DHRS4 PE=2 SV=1
Length = 260
Score = 131 bits (327), Expect = 1e-029
Identities = 82/251 (32%), Positives = 134/251 (53%), Gaps = 2/251 (0%)
Frame = +2
Query: 44 MDKRWSLEGTTALVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKKKGFQV 223
M +R L+ ALVT GIG AI LA G V + +++++ K +G V
Sbjct: 6 MARRNPLDNKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDRAVATLKGEGLSV 65
Query: 224 SGSVCDVSSRSEREKLMQTVSTMFNGKLNILVNNVA-SARVKPTTEYHEDDFSFHISTNL 400
+G+VC V +RE+L+ T + +G ++IL++N A S + E+ + + N+
Sbjct: 66 TGTVCHVGKAEDRERLVAT-AVKLHGGVDILISNAAVSPFFGSLMDVPEEVWDKILDVNV 124
Query: 401 ESAYHLSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACEWAK 580
++ L++ P + GSIV +SSIA Y+++K AL L +NLA E A+
Sbjct: 125 KATALLTKAVVPEMAKRGGGSIVIVSSIAAYSPFPSLGPYNVSKTALLGLTKNLALELAE 184
Query: 581 DGIRANAVAPNFIYTALAKPFLDDAGFNKSLSSRTPLGRPGEPKEVASLVAFLCLPAASY 760
+R N +AP I T+ ++ +D +S+ + + R G+P+E A +V+FLC ASY
Sbjct: 185 SNVRVNCLAPGLIRTSFSRVLWEDPARQESIKATFQIKRIGKPEECAGIVSFLCSEDASY 244
Query: 761 ITGQTICVDGG 793
ITG+T+ V GG
Sbjct: 245 ITGETVVVAGG 255
>sp|P50842|KDUD_BACSU 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase OS=Bacillus
subtilis GN=kduD PE=3 SV=1
Length = 254
Score = 127 bits (319), Expect = 1e-028
Identities = 83/251 (33%), Positives = 131/251 (52%), Gaps = 13/251 (5%)
Frame = +2
Query: 56 WSLEGTTALVTGGASGIGHAIVEELAGFGCKV----HACDLSETLLNQSLCEWKKKGFQV 223
+SL+G TALVTG +GIG I + LAG G + H LSET Q L E ++G
Sbjct: 8 FSLKGKTALVTGPGTGIGQGIAKALAGAGADIIGTSHTSSLSET---QQLVE--QEGRIF 62
Query: 224 SGSVCDVSSRSEREKLMQTVSTMF-NGKLNILVNNVASARVKPTTEYHEDDFSFHISTNL 400
+ D+ S+ E + + + +F N +++ILVNN + ++ E+++ ++ NL
Sbjct: 63 TSFTLDM---SKPEAIKDSAAELFENRQIDILVNNAGIIHREKAEDFPEENWQHVLNVNL 119
Query: 401 ESAYHLSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACEWAK 580
S + L+QL+ + G I+ I+S+ Y+ +K A+ L ++ A EWA
Sbjct: 120 NSLFILTQLAGRHMLKRGHGKIINIASLLSFQGGILVPAYTASKHAVAGLTKSFANEWAA 179
Query: 581 DGIRANAVAPNFIYTALAKPFLDDAGFNKSLSSRTPLGRPGEPKEVASLVAFLCLPAASY 760
GI+ NA+AP +I TA KP DD N+ + R P GR G+ ++ FL A+ Y
Sbjct: 180 SGIQVNAIAPGYISTANTKPIRDDEKRNEDILKRIPAGRWGQADDIGGTAVFLASRASDY 239
Query: 761 ITGQTICVDGG 793
+ G + VDGG
Sbjct: 240 VNGHILAVDGG 250
>sp|P50199|GNO_GLUOX Gluconate 5-dehydrogenase OS=Gluconobacter oxydans GN=gno
PE=1 SV=1
Length = 256
Score = 126 bits (316), Expect = 2e-028
Identities = 75/252 (29%), Positives = 134/252 (53%), Gaps = 5/252 (1%)
Frame = +2
Query: 56 WSLEGTTALVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKKKGFQVSGSV 235
+SL G ALVTG + GIG + + LA +G +V + L+ + ++ +G + S +V
Sbjct: 7 FSLSGARALVTGASRGIGLTLAKGLARYGAEVVLNGRNAESLDSAQSGFEAEGLKASTAV 66
Query: 236 CDVSSRSEREKLMQTVSTMFN--GKLNILVNNVASARVKPTTEYHEDDFSFHISTNLESA 409
DV ++++ ++ V+ + G ++IL+NN R P E+ D+ +STN+ +
Sbjct: 67 FDV---TDQDAVIDGVAAIERDMGPIDILINNAGIQRRAPLEEFSRKDWDDLMSTNVNAV 123
Query: 410 YHLSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACEWAKDGI 589
+ + Q + G IV I S+ ++ + Y+ TKGA+ L + +A +W + G+
Sbjct: 124 FFVGQAVARHMIPRGRGKIVNICSVQSELARPGIAPYTATKGAVKNLTKGMATDWGRHGL 183
Query: 590 RANAVAPNFIYTALAKPFLDDAGFNKSLSSRTPLGRPGEPKEVASLVAFLCLPAASYITG 769
+ N +AP + T + + + D F L RTP GR G+ +E+ FL A+S++ G
Sbjct: 184 QINGLAPGYFATEMTERLVADEEFTDWLCKRTPAGRWGQVEELVGAAVFLSSRASSFVNG 243
Query: 770 QTICVDGGLTVN 805
Q + VDGG+TV+
Sbjct: 244 QVLMVDGGITVS 255
>sp|Q9BTZ2|DHRS4_HUMAN Dehydrogenase/reductase SDR family member 4 OS=Homo
sapiens GN=DHRS4 PE=1 SV=2
Length = 260
Score = 124 bits (310), Expect = 1e-027
Identities = 83/254 (32%), Positives = 132/254 (51%), Gaps = 8/254 (3%)
Frame = +2
Query: 44 MDKRWSLEGTTALVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKKKGFQV 223
M +R L ALVT GIG AI LA G V + ++Q++ + +G V
Sbjct: 6 MTRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSV 65
Query: 224 SGSVCDVSSRSEREKLMQTVSTMFNGKLNILVNNVASARVKP----TTEYHEDDFSFHIS 391
+G+VC V +RE+L+ T + +G ++ILV+N A V P + E+ + +
Sbjct: 66 TGTVCHVGKAEDRERLVAT-AVKLHGGIDILVSNAA---VNPFFGSIMDVTEEVWDKTLD 121
Query: 392 TNLESAYHLSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACE 571
N+++ +++ P ++ GS+V +SSIA S Y+++K AL L + LA E
Sbjct: 122 INVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIE 181
Query: 572 WAKDGIRANAVAPNFIYTALAKPFLDDAGFNKSLSSRTPLGRPGEPKEVASLVAFLCLPA 751
A IR N +AP I T+ ++ D +S+ + R GEP++ A +V+FLC
Sbjct: 182 LAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSED 241
Query: 752 ASYITGQTICVDGG 793
ASYITG+T+ V GG
Sbjct: 242 ASYITGETVVVGGG 255
>sp|Q5RCF8|DHRS4_PONAB Dehydrogenase/reductase SDR family member 4 OS=Pongo
abelii GN=DHRS4 PE=2 SV=2
Length = 260
Score = 124 bits (310), Expect = 1e-027
Identities = 83/254 (32%), Positives = 132/254 (51%), Gaps = 8/254 (3%)
Frame = +2
Query: 44 MDKRWSLEGTTALVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKKKGFQV 223
M +R L ALVT GIG AI LA G V + ++Q++ + +G V
Sbjct: 6 MTRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSV 65
Query: 224 SGSVCDVSSRSEREKLMQTVSTMFNGKLNILVNNVASARVKP----TTEYHEDDFSFHIS 391
+G+VC V +RE+L+ T + +G ++ILV+N A V P + E+ + +
Sbjct: 66 TGTVCHVGKAEDRERLVAT-AVKLHGGIDILVSNAA---VNPFFGSLMDVTEEVWDKTLD 121
Query: 392 TNLESAYHLSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACE 571
N+++ +++ P ++ GS+V +SSIA S Y+++K AL L + LA E
Sbjct: 122 INVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIE 181
Query: 572 WAKDGIRANAVAPNFIYTALAKPFLDDAGFNKSLSSRTPLGRPGEPKEVASLVAFLCLPA 751
A IR N +AP I T+ ++ D +S+ + R GEP++ A +V+FLC
Sbjct: 182 LAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSED 241
Query: 752 ASYITGQTICVDGG 793
ASYITG+T+ V GG
Sbjct: 242 ASYITGETVVVGGG 255
>sp|Q9GKX2|DHRS4_RABIT Dehydrogenase/reductase SDR family member 4
OS=Oryctolagus cuniculus GN=DHRS4 PE=1 SV=1
Length = 260
Score = 123 bits (308), Expect = 2e-027
Identities = 79/252 (31%), Positives = 134/252 (53%), Gaps = 8/252 (3%)
Frame = +2
Query: 50 KRWSLEGTTALVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKKKGFQVSG 229
+R L A+VT GIG AI LA G V + +++++ + +G V+G
Sbjct: 8 RRDPLANKVAIVTASTDGIGLAIARRLAQDGAHVVISSRKQQNVDRAVAALQAEGLSVTG 67
Query: 230 SVCDVSSRSEREKLMQTVSTMFNGKLNILVNNVASARVKP----TTEYHEDDFSFHISTN 397
+VC V +RE+L+ T + +G ++ILV+N A V P + E+ + + N
Sbjct: 68 TVCHVGKAEDRERLVATALNL-HGGIDILVSNAA---VNPFFGKLMDVTEEVWDKILDIN 123
Query: 398 LESAYHLSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACEWA 577
+++ +++ P ++ GS+V ++SIA + Y+++K AL L +NLA E A
Sbjct: 124 VKAMALMTKAVVPEMEKRGGGSVVIVASIAAFNPFSGLGPYNVSKTALVGLTKNLALELA 183
Query: 578 KDGIRANAVAPNFIYTALAKPFLDDAGFNKSLSSRTPLGRPGEPKEVASLVAFLCLPAAS 757
IR N +AP I T+ +K +D +++ + + R G+P+E A +V+FLC AS
Sbjct: 184 AQNIRVNCLAPGLIKTSFSKALWEDKAQEENIIQKLRIRRLGKPEECAGIVSFLCSEDAS 243
Query: 758 YITGQTICVDGG 793
YITG+T+ V GG
Sbjct: 244 YITGETVVVAGG 255
>sp|P0A9Q0|IDNO_ECOL6 Gluconate 5-dehydrogenase OS=Escherichia coli O6 GN=idnO
PE=3 SV=1
Length = 254
Score = 120 bits (299), Expect = 2e-026
Identities = 67/249 (26%), Positives = 127/249 (51%), Gaps = 1/249 (0%)
Frame = +2
Query: 56 WSLEGTTALVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKKKGFQVSGSV 235
+SL G L+TG A GIG + L +G ++ D++ ++ + ++G Q +
Sbjct: 5 FSLAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVEKLHQEGIQAVAAP 64
Query: 236 CDVSSRSEREKLMQTVSTMFNGKLNILVNNVASARVKPTTEYHEDDFSFHISTNLESAYH 415
+V+ + E + ++ + G +++LVNN R P TE+ E +++ I+ N + +
Sbjct: 65 FNVTHKHEIDAAVEHIEKDI-GPIDVLVNNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFL 123
Query: 416 LSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACEWAKDGIRA 595
+SQ + ++G ++ I S+ + + + Y+ +KGA+ L R + E A+ I+
Sbjct: 124 VSQAVTRHMVERKAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHNIQV 183
Query: 596 NAVAPNFIYTALAKPFLDDAGFNKSLSSRTPLGRPGEPKEVASLVAFLCLPAASYITGQT 775
N +AP + T + K ++D F L RTP R G+P+E+ FL A+ ++ G
Sbjct: 184 NGIAPGYFKTEMTKALVEDEAFTAWLCKRTPAARWGDPQELIGAAVFLSSKASDFVNGHL 243
Query: 776 ICVDGGLTV 802
+ VDGG+ V
Sbjct: 244 LFVDGGMLV 252
>sp|P0A9P9|IDNO_ECOLI Gluconate 5-dehydrogenase OS=Escherichia coli (strain K12)
GN=idnO PE=3 SV=1
Length = 254
Score = 120 bits (299), Expect = 2e-026
Identities = 67/249 (26%), Positives = 127/249 (51%), Gaps = 1/249 (0%)
Frame = +2
Query: 56 WSLEGTTALVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKKKGFQVSGSV 235
+SL G L+TG A GIG + L +G ++ D++ ++ + ++G Q +
Sbjct: 5 FSLAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVEKLHQEGIQAVAAP 64
Query: 236 CDVSSRSEREKLMQTVSTMFNGKLNILVNNVASARVKPTTEYHEDDFSFHISTNLESAYH 415
+V+ + E + ++ + G +++LVNN R P TE+ E +++ I+ N + +
Sbjct: 65 FNVTHKHEIDAAVEHIEKDI-GPIDVLVNNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFL 123
Query: 416 LSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACEWAKDGIRA 595
+SQ + ++G ++ I S+ + + + Y+ +KGA+ L R + E A+ I+
Sbjct: 124 VSQAVTRHMVERKAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHNIQV 183
Query: 596 NAVAPNFIYTALAKPFLDDAGFNKSLSSRTPLGRPGEPKEVASLVAFLCLPAASYITGQT 775
N +AP + T + K ++D F L RTP R G+P+E+ FL A+ ++ G
Sbjct: 184 NGIAPGYFKTEMTKALVEDEAFTAWLCKRTPAARWGDPQELIGAAVFLSSKASDFVNGHL 243
Query: 776 ICVDGGLTV 802
+ VDGG+ V
Sbjct: 244 LFVDGGMLV 252
>sp|Q99LB2|DHRS4_MOUSE Dehydrogenase/reductase SDR family member 4 OS=Mus
musculus GN=Dhrs4 PE=2 SV=1
Length = 260
Score = 116 bits (289), Expect = 3e-025
Identities = 77/254 (30%), Positives = 123/254 (48%), Gaps = 8/254 (3%)
Frame = +2
Query: 44 MDKRWSLEGTTALVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKKKGFQV 223
+ +R L ALVT GIG AI LA G V + +++++ + +G V
Sbjct: 6 LTRRNPLSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATLQGEGLSV 65
Query: 224 SGSVCDVSSRSEREKLMQTVSTMFNGKLNILVNNVASARVKP----TTEYHEDDFSFHIS 391
+G VC V +REKL+ T G ++ILV+N A V P + E+ + +S
Sbjct: 66 TGIVCHVGKAEDREKLITTALKRHRG-IDILVSNAA---VNPFFGNLMDVTEEVWDKVLS 121
Query: 392 TNLESAYHLSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACE 571
N+ + + + P ++ GS+V + S+AG Y+++K AL L +N A E
Sbjct: 122 INVTATAMMIKAVVPEMEKRGGGSVVIVGSVAGFTRFPSLGPYNVSKTALLGLTKNFAAE 181
Query: 572 WAKDGIRANAVAPNFIYTALAKPFLDDAGFNKSLSSRTPLGRPGEPKEVASLVAFLCLPA 751
A IR N +AP I T + ++ + + R G+P++ A +V+FLC
Sbjct: 182 LAPKNIRVNCLAPGLIKTRFSSVLWEEKAREDFIKEAMQIRRLGKPEDCAGIVSFLCSED 241
Query: 752 ASYITGQTICVDGG 793
ASYI G+T+ V GG
Sbjct: 242 ASYINGETVVVGGG 255
>sp|Q13268|DHRS2_HUMAN Dehydrogenase/reductase SDR family member 2 OS=Homo
sapiens GN=DHRS2 PE=1 SV=3
Length = 258
Score = 115 bits (286), Expect = 7e-025
Identities = 80/250 (32%), Positives = 127/250 (50%), Gaps = 3/250 (1%)
Frame = +2
Query: 44 MDKRWSLEGTTALVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKKKGFQV 223
+D++ L A+VTG SGIG AI LA G V + +++++ + + +G V
Sbjct: 6 IDRKGVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSV 65
Query: 224 SGSVCDVSSRSEREKLMQTVSTMFNGKLNILVNNVASARVKPTTEYHEDDFSFHISTNLE 403
+G VC V +RE+L+ G ++ + + V T E + +S N++
Sbjct: 66 AGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVK 125
Query: 404 S-AYHLSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACEWAK 580
S A LSQL P+++ + G+++ +SSIA + +Y+++K AL L R LA E A
Sbjct: 126 SPALLLSQLL-PYME-NRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAP 183
Query: 581 DGIRANAVAPNFIYTALAKPFLDDAGFNKSLSSRTPLGRPGEPKEVASLVAFLCLPAASY 760
IR N V P I T +K F + K+ L R GE ++ A +V+FLC P ASY
Sbjct: 184 KDIRVNCVVPGIIKTDFSKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASY 243
Query: 761 ITGQTICVDG 790
+ G+ I V G
Sbjct: 244 VNGENIAVAG 253
>sp|Q8VID1|DHRS4_RAT Dehydrogenase/reductase SDR family member 4 OS=Rattus
norvegicus GN=Dhrs4 PE=2 SV=1
Length = 260
Score = 114 bits (285), Expect = 9e-025
Identities = 76/248 (30%), Positives = 123/248 (49%), Gaps = 8/248 (3%)
Frame = +2
Query: 62 LEGTTALVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKKKGFQVSGSVCD 241
L ALVT GIG AI LA G V + +++++ + +G V+G VC
Sbjct: 12 LANKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATLQGEGLSVTGVVCH 71
Query: 242 VSSRSEREKLMQTVSTMFNGKLNILVNNVASARVKP----TTEYHEDDFSFHISTNLESA 409
V +REKL+ + G ++ILV+N A V P + E+ ++ +S N+ ++
Sbjct: 72 VGKAEDREKLVNMALKLHQG-IDILVSNAA---VNPFFGNLMDVTEEVWNKVLSINVTAS 127
Query: 410 YHLSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACEWAKDGI 589
+ + P ++ GS+V +SS+AG V Y+++K AL L +N A E A I
Sbjct: 128 AMMIKAVVPAMEKRGGGSVVIVSSVAGFVLFPSLGPYNVSKTALLGLTKNFAAELAPKNI 187
Query: 590 RANAVAPNFIYTALAKPFLDDAGFNKSLSSRTPLGRPGEPKEVASLVAFLCLPAASYITG 769
R N +AP I T + + + + + R G+P++ +V+FLC ASYI G
Sbjct: 188 RVNCLAPGLIKTHFSSVLWKEKAREEMIKETMQIRRLGKPEDCVGIVSFLCSEDASYING 247
Query: 770 QTICVDGG 793
+T+ V GG
Sbjct: 248 ETVVVGGG 255
>sp|Q8GAV9|CPNA_COMS9 Cyclopentanol dehydrogenase OS=Comamonas sp. (strain NCIMB
9872) GN=cpnA PE=1 SV=1
Length = 250
Score = 111 bits (275), Expect = 1e-023
Identities = 73/242 (30%), Positives = 121/242 (50%), Gaps = 1/242 (0%)
Frame = +2
Query: 80 LVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKKKGFQVSGSVCDVSSRSE 259
LVTGGA G+G LA G V+ D++E L +Q++ E +++G + DV++ +
Sbjct: 10 LVTGGAMGMGLTHCTLLAREGATVYLSDMNEELGHQAVAEIRRQGGKAHFLHLDVTNENH 69
Query: 260 REKLMQTVSTMFNGKLNILVNNVASARVKPTTEYHEDDFSFHISTNLESAYHLSQLSHPF 439
+ T+ + +L+ LVNN +KP + +++ N+ S + ++
Sbjct: 70 WTGAVDTILAE-SDRLDALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTRAVIEP 128
Query: 440 LKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACEWAKDGIRANAVAPNFI 619
++ + G IV +SSI G+V + Y +KGA+ + A + A IR N+V P I
Sbjct: 129 MRKAHKGCIVNVSSIYGLVGAPGAAAYEASKGAVRLFTKACAVDLAPFNIRVNSVHPGVI 188
Query: 620 YTALAKPFLDDAGFNKSLSSRTPLGRPGEPKEVASLVAFLCLPAASYITGQTICVDGGLT 799
T + + LD ++L T LGR +P EV+ V FL AS++ G + VDGG T
Sbjct: 189 ATPMTQQILDAPQSARALLGPTLLGRAAQPMEVSQAVLFLVSDEASFVHGSELVVDGGYT 248
Query: 800 VN 805
N
Sbjct: 249 AN 250
>sp|Q937L4|CPNA_COMTE Cyclopentanol dehydrogenase OS=Comamonas testosteroni
GN=cpnA PE=3 SV=1
Length = 250
Score = 111 bits (275), Expect = 1e-023
Identities = 73/242 (30%), Positives = 121/242 (50%), Gaps = 1/242 (0%)
Frame = +2
Query: 80 LVTGGASGIGHAIVEELAGFGCKVHACDLSETLLNQSLCEWKKKGFQVSGSVCDVSSRSE 259
LVTGGA G+G LA G V+ D++E L +Q++ E +++G + DV++ +
Sbjct: 10 LVTGGAMGMGLTHCTLLAREGATVYLSDMNEELGHQAVAEIRRQGGKAHFLHLDVTNENH 69
Query: 260 REKLMQTVSTMFNGKLNILVNNVASARVKPTTEYHEDDFSFHISTNLESAYHLSQLSHPF 439
+ T+ + +L+ LVNN +KP + +++ N+ S + ++
Sbjct: 70 WTGAVDTILAE-SDRLDALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTRAVIEP 128
Query: 440 LKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACEWAKDGIRANAVAPNFI 619
++ + G IV +SSI G+V + Y +KGA+ + A + A IR N+V P I
Sbjct: 129 MRKAHKGCIVNVSSIYGLVGAPGAAAYEASKGAVRLFTKACAVDLAPFNIRVNSVHPGVI 188
Query: 620 YTALAKPFLDDAGFNKSLSSRTPLGRPGEPKEVASLVAFLCLPAASYITGQTICVDGGLT 799
T + + LD ++L T LGR +P EV+ V FL AS++ G + VDGG T
Sbjct: 189 ATPMTQQILDAPQSARALLGPTLLGRAAQPMEVSQAVLFLVSDEASFVHGSELVVDGGYT 248
Query: 800 VN 805
N
Sbjct: 249 AN 250
>sp|P76633|YGCW_ECOLI Uncharacterized oxidoreductase ygcW OS=Escherichia coli
(strain K12) GN=ygcW PE=3 SV=2
Length = 261
Score = 100 bits (247), Expect = 2e-020
Identities = 70/253 (27%), Positives = 117/253 (46%), Gaps = 10/253 (3%)
Frame = +2
Query: 56 WSLEGTTALVTGGASGIGHAIVEELAGFGCKV----HACDLSETLLNQSLCEWKKKGFQV 223
+SL+G TA+VTGG SG+G A LA G + D ET + + E K+G +V
Sbjct: 14 FSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGET---KEMIE--KQGVEV 68
Query: 224 SGSVCDVSSRSEREKLMQTVSTMFNGKLNILVNNVASARVKPTTEYHEDDFSFHISTNLE 403
+++ +K++ F G ++ILVNN ++ ++ D+ I NL
Sbjct: 69 DFMQVGITAEGAPQKIIAACCERF-GTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLT 127
Query: 404 SAYHLSQLSHPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACEWAKD 583
+A+ LS + + +SG I+ I S+ + YS TK AL + E +
Sbjct: 128 AAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQY 187
Query: 584 GIRANAVAPNFIYTALAKPFLDDAGFNKSLSSRTPLGRPGEPKEVASLVAFLCLPAASYI 763
I+ N +AP + T + + N+ + P R G+ +++ FL PA++Y+
Sbjct: 188 NIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYV 247
Query: 764 TGQTICVDGGLTV 802
G + VDGG V
Sbjct: 248 NGHLLVVDGGYLV 260
>sp|P71079|FABL_BACSU Enoyl-[acyl-carrier-protein] reductase [NADPH] OS=Bacillus
subtilis GN=fabL PE=1 SV=1
Length = 250
Score = 96 bits (238), Expect = 3e-019
Identities = 73/241 (30%), Positives = 117/241 (48%), Gaps = 4/241 (1%)
Frame = +2
Query: 77 ALVTGGASGIGHAIVEELA--GFGCKVHACDLSETLLNQSLCEWKKKGFQVSGSVCDVSS 250
ALVTG + G+G A LA G+ ++ + L ++ E +K G +V +V
Sbjct: 7 ALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAAL-ETAEEIEKLGVKVLVVKANVGQ 65
Query: 251 RSEREKLMQTVSTMFNGKLNILVNNVASARVKPTTEYHEDDFSFHISTNLESAYHLSQLS 430
++ +++ Q + F G+L++ VNN AS ++P E E + + ++ N ++ +Q +
Sbjct: 66 PAKIKEMFQQIDETF-GRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLFCAQEA 124
Query: 431 HPFLKASESGSIVFISSIAGIVSINCGSMYSLTKGALNQLARNLACEWAKDGIRANAVAP 610
++ + G IV ISS+ I + + ++K AL L R LA E + I NAV+
Sbjct: 125 AKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNAVSG 184
Query: 611 NFIYTALAKPFLDDAGFNKSLSSRTPLGRPGEPKEVASLVAFLCLPAASYITGQTICVDG 790
I T K F + + TP GR E K++ V FL A I GQTI VDG
Sbjct: 185 GAIDTDALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADMIRGQTIIVDG 244
Query: 791 G 793
G
Sbjct: 245 G 245
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,801,685,782
Number of Sequences: 518415
Number of Extensions: 36801685782
Number of Successful Extensions: 258262551
Number of sequences better than 0.0: 0
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