BLASTX 7.6.2
Query= UN09250 /QuerySize=1142
(1141 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O65355|GGH_ARATH Gamma-glutamyl hydrolase OS=Arabidopsis thal... 388 4e-107
sp|P93164|GGH_SOYBN Gamma-glutamyl hydrolase OS=Glycine max PE=2... 255 4e-067
sp|Q54LN4|GGHA_DICDI Gamma-glutamyl hydrolase A OS=Dictyostelium... 156 3e-037
sp|Q54HL4|GGHB_DICDI Gamma-glutamyl hydrolase B OS=Dictyostelium... 150 2e-035
sp|Q9Z0L8|GGH_MOUSE Gamma-glutamyl hydrolase OS=Mus musculus GN=... 145 8e-034
sp|Q92820|GGH_HUMAN Gamma-glutamyl hydrolase OS=Homo sapiens GN=... 141 2e-032
sp|A7YWG4|GGH_BOVIN Gamma-glutamyl hydrolase OS=Bos taurus GN=GG... 139 4e-032
sp|Q62867|GGH_RAT Gamma-glutamyl hydrolase OS=Rattus norvegicus ... 133 3e-030
>sp|O65355|GGH_ARATH Gamma-glutamyl hydrolase OS=Arabidopsis thaliana GN=GGH
PE=1 SV=2
Length = 347
Score = 388 bits (996), Expect = 4e-107
Identities = 179/237 (75%), Positives = 212/237 (89%)
Frame = +1
Query: 262 ELVNGLIFTGGWAKKYEYFDMVTKIFQKALERNDAGEHFPIYGICLGFELMSIIVSQNRD 441
ELVNG+I TGGWAK+ YF++V KIF K LERNDAGEHFPIY ICLGFEL+++I+SQNRD
Sbjct: 111 ELVNGVILTGGWAKEGLYFEIVKKIFNKVLERNDAGEHFPIYAICLGFELLTMIISQNRD 170
Query: 442 ILERFDAEDNASSLQFVENVNIEGTLFQRFPPELLRKVSTDCLVMQKHKWGITPEKFKAN 621
I E+ DA ++ASSLQFVENVNI+GT+FQRFPPELL+K+ TDCLVMQ H++GI+P+ F+ N
Sbjct: 171 IFEKMDARNSASSLQFVENVNIQGTIFQRFPPELLKKLGTDCLVMQNHRFGISPQSFEGN 230
Query: 622 HALSSFFEIVTTCIDENSKTYVSTVKAKRYPITGFQWHPEKNAFEWGSSQIPHSADAIQV 801
ALS+FF+IVTTC+D+N K YVSTV++ +YP+TGFQWHPEKNAFEWGSS+IPHS DAIQV
Sbjct: 231 IALSNFFKIVTTCVDDNGKVYVSTVQSTKYPVTGFQWHPEKNAFEWGSSKIPHSEDAIQV 290
Query: 802 TQYAASHLVSEARKSQNRPSSEKVLKNLIYNYKPTYCGYAGKGYDEVYLFTQPRSRL 972
TQ+AA+HLVSEARKS NRP S+KVL NLIYNYKPTYCGYAG GYDEVY+FTQ RS L
Sbjct: 291 TQHAANHLVSEARKSLNRPESKKVLSNLIYNYKPTYCGYAGIGYDEVYIFTQQRSLL 347
Score = 89 bits (218), Expect = 7e-017
Identities = 48/80 (60%), Positives = 57/80 (71%), Gaps = 5/80 (6%)
Frame = +2
Query: 47 MWKLCFCLPFLLL----DVGVAKASASIYLPSQTGVDGSSNPVCSSPDPNLNYRPVIGIL 214
MW + LP + L D + +A+I LPSQTG D S +PVCS+PDPNLNYRPVIGIL
Sbjct: 1 MWSYVW-LPLVALSLFKDSIIMAKAATILLPSQTGFDISRSPVCSAPDPNLNYRPVIGIL 59
Query: 215 SHPGDGASGRLINDTTS*SM 274
SHPGDGASGRL N T + S+
Sbjct: 60 SHPGDGASGRLSNATDASSI 79
>sp|P93164|GGH_SOYBN Gamma-glutamyl hydrolase OS=Glycine max PE=2 SV=1
Length = 342
Score = 255 bits (651), Expect = 4e-067
Identities = 125/231 (54%), Positives = 162/231 (70%), Gaps = 1/231 (0%)
Frame = +1
Query: 262 ELVNGLIFTGGWAKKYEYFDMVTKIFQKALERNDAGEHFPIYGICLGFELMSIIVSQNRD 441
+LVNG++FTGGWA Y D + IF+KALERNDAG+HFP+ LG L+ IVS+ D
Sbjct: 111 DLVNGVLFTGGWAVSGPYLDTLGNIFKKALERNDAGDHFPVIAFNLGGNLVIRIVSEQTD 170
Query: 442 ILERFDAEDNASSLQFVENVNIEGTLFQRFPPELLRKVSTDCLVMQKHKWGITPEKFKAN 621
ILE F A SSL N +G+LFQRFP +LL ++ TDCLV+ H++ I+P K + N
Sbjct: 171 ILEPFTASSLPSSLVLWNEANAKGSLFQRFPSDLLTQLKTDCLVLHNHRYAISPRKLQYN 230
Query: 622 HALSSFFEIVTTCIDENSKTYVSTVKAKRYPITGFQWHPEKNAFEWGSS-QIPHSADAIQ 798
LS FFEI+ T D + KT+VST + ++YP+T W PEKNAFEW +S + PH+ DAI+
Sbjct: 231 TKLSDFFEILATSGDRDGKTFVSTARGRKYPVTVNLWQPEKNAFEWATSLKAPHTEDAIR 290
Query: 799 VTQYAASHLVSEARKSQNRPSSEKVLKNLIYNYKPTYCGYAGKGYDEVYLF 951
VTQ A+ +SEARKS N P ++KV +LIYNYKPT+ G AGKGYD+VYLF
Sbjct: 291 VTQSTANFFISEARKSTNTPDAQKVRDSLIYNYKPTFGGTAGKGYDQVYLF 341
Score = 63 bits (152), Expect = 3e-009
Identities = 31/48 (64%), Positives = 38/48 (79%), Gaps = 2/48 (4%)
Frame = +2
Query: 116 IYLPSQTGVDGSSNPVCSSPDPNLNYRPVIGILSHPGDGASGRLINDT 259
I+LPSQ D S + C++ DP+LNY+PVIGIL+HPGDGASGRL N T
Sbjct: 29 IFLPSQLHDDDSVS--CTATDPSLNYKPVIGILTHPGDGASGRLSNAT 74
>sp|Q54LN4|GGHA_DICDI Gamma-glutamyl hydrolase A OS=Dictyostelium discoideum
GN=gghA PE=3 SV=1
Length = 317
Score = 156 bits (393), Expect = 3e-037
Identities = 72/233 (30%), Positives = 140/233 (60%), Gaps = 6/233 (2%)
Frame = +1
Query: 268 VNGLIFTGG---WAKKYEYFDMVTKIFQKALERNDAGEHFPIYGICLGFELMSIIVSQNR 438
+NG+ F GG + + Y D + I+ + +E N+ G++FP++G C+GF+ ++++ + N
Sbjct: 85 INGVFFPGGGVDFNNQTVYTDTIQSIWSQVVEFNNNGDYFPLWGTCMGFQELALLSADNF 144
Query: 439 DILERFDAEDNASSLQFVENVNIEGTLFQRFPPELLRKVSTDCLVMQKHKWGITPEKFKA 618
++L +++E+ L F ++ LF +++ ++++ + M H++G++P+ ++
Sbjct: 145 NLLSSYNSENYTVPLNFT-SLAAGSRLFSLASSSIMQSLASEPITMNNHQFGLSPQTYQQ 203
Query: 619 NHALSSFFEIVTTCIDENSKTYVSTVKAKRYPITGFQWHPEKNAFEWGSSQI-PHSADAI 795
++++FF++++T +D + T++ST++AK YPI G QWHPEK FEW ++ HS D+I
Sbjct: 204 TSSINTFFDVLSTNVDRDGNTFISTIEAKNYPIYGTQWHPEKPIFEWWDQEVMNHSFDSI 263
Query: 796 QVTQYAASHLVSEARKSQNRPSSEKV-LKNLIYNYKPTYCGYAGKGYDEVYLF 951
QY ++ V+E RKS + S V LIYNY P Y ++++Y F
Sbjct: 264 MANQYTSNFFVNECRKSLHSFSDPSVEASTLIYNYTPQYSESTVPDFEQIYYF 316
>sp|Q54HL4|GGHB_DICDI Gamma-glutamyl hydrolase B OS=Dictyostelium discoideum
GN=gghB PE=3 SV=1
Length = 347
Score = 150 bits (378), Expect = 2e-035
Identities = 77/233 (33%), Positives = 136/233 (58%), Gaps = 7/233 (3%)
Frame = +1
Query: 268 VNGLIFTGG---WAKKYEYFDMVTKIFQKALERNDAGEHFPIYGICLGFELMSIIVSQNR 438
+NG++ GG + + +Y +T I+ L+ N G++FP++G CLG E + + +++
Sbjct: 83 INGILLPGGDVDFKTEIQYVKTLTLIWDYVLDVNINGDYFPLWGTCLGLEEIVSLQAESF 142
Query: 439 DILERFDAEDNASSLQFVENVNIEGTLFQRFPPELLRKVSTDCLVMQKHKWGITPEKFKA 618
D+L F+AE+ + L F N+ +E + + P ++ ++ D + M H +GI+P F
Sbjct: 143 DVLTDFNAENYSIPLNF-SNIALESKIMKNCPTNIINSLANDPITMNNHHFGISPNTFDN 201
Query: 619 NHALSSFFEIVTTCIDENSKTYVSTVKAKRYPITGFQWHPEKNAFEWGSSQ-IPHSADAI 795
N L+ FF ++ T D++ ++S +++K YPI WHPEK+ + W S HS +AI
Sbjct: 202 NSLLNQFFNVLATNNDKSGNEFISLIESKDYPIYAIIWHPEKSPYSWYSKDATDHSFNAI 261
Query: 796 QVTQYAASHLVSEARKSQNRPSSEKVL-KNLIYNYKPTYCGYAGKGYDEVYLF 951
QY ++ V+E RKS ++ + E+VL K+LIYNY PTY + +++Y+F
Sbjct: 262 LACQYMSNFFVNETRKSNHKFNDEEVLFKSLIYNYNPTYT-FKETHVEQIYIF 313
>sp|Q9Z0L8|GGH_MOUSE Gamma-glutamyl hydrolase OS=Mus musculus GN=Ggh PE=1 SV=1
Length = 317
Score = 145 bits (364), Expect = 8e-034
Identities = 91/244 (37%), Positives = 134/244 (54%), Gaps = 15/244 (6%)
Frame = +1
Query: 247 DQ*YNEL---VNGLIFTGGWAKKYEY-FDMVTKI-FQKALERNDAGEHFPIYGICLGFEL 411
D Y EL +NG++ GG A + + V KI F KALE D G HFP++G CLGFE
Sbjct: 79 DAEYEELFRSINGVLLPGGGANLTDSGYSRVAKIFFSKALESFDNGGHFPVWGTCLGFEE 138
Query: 412 MSIIVSQNRDILERFDAEDNASSLQFVENVNIEGTLFQRFPPELLRKVSTDCLVMQKHKW 591
+S++VS ++L D + L F E + +F+ FP ELL ++ + L HKW
Sbjct: 139 LSVLVS-GENLLTSTDTKSKKLPLNFTEGAR-KNKMFKHFPTELLDSLALENLTANFHKW 196
Query: 592 GITPEKFKANHALSSFFEIVTTCIDENSKTYVSTVKAKRYPITGFQWHPEKNAFEWGS-S 768
++ + F N L FF I+TT D ++ ++S+++ +YP+ QWHPEK FEW +
Sbjct: 197 SLSVKNFTENEKLKKFFNILTTNTDGKTE-FISSMEGFKYPVYAVQWHPEKAPFEWKNLG 255
Query: 769 QIPHSADAIQVTQYAASHLVSEARKSQNRPSSEKVLK---NLIYNYKPTYCGYAGKGYDE 939
I H+ +A++ + Y A LVSEARK N E V+K +LIY P Y G + +
Sbjct: 256 GISHAPNAVKTSFYLAEFLVSEARK--NSHHFENVVKETASLIYKVYPIYTGNI-SSFQQ 312
Query: 940 VYLF 951
Y+F
Sbjct: 313 AYMF 316
>sp|Q92820|GGH_HUMAN Gamma-glutamyl hydrolase OS=Homo sapiens GN=GGH PE=1 SV=2
Length = 318
Score = 141 bits (353), Expect = 2e-032
Identities = 77/232 (33%), Positives = 128/232 (55%), Gaps = 8/232 (3%)
Frame = +1
Query: 268 VNGLIFTGGWA--KKYEYFDMVTKIFQKALERNDAGEHFPIYGICLGFELMSIIVSQNRD 441
+NG++F GG ++ +Y + + +++ D G++FP++G CLGFE +S+++S
Sbjct: 90 INGILFPGGSVDLRRSDYAKVAKIFYNLSIQSFDDGDYFPVWGTCLGFEELSLLIS-GEC 148
Query: 442 ILERFDAEDNASSLQFVENVNIEGTLFQRFPPELLRKVSTDCLVMQKHKWGITPEKFKAN 621
+L D D A L F + +FQ FP ELL ++ + L HKW ++ + F N
Sbjct: 149 LLTATDTVDVAMPLNFTGG-QLHSRMFQNFPTELLLSLAVEPLTANFHKWSLSVKNFTMN 207
Query: 622 HALSSFFEIVTTCIDENSKTYVSTVKAKRYPITGFQWHPEKNAFEWGS-SQIPHSADAIQ 798
L FF ++TT D + ++ST++ +YP+ G QWHPEK +EW + I H+ +A++
Sbjct: 208 EKLKKFFNVLTTNTDGKIE-FISTMEGYKYPVYGVQWHPEKAPYEWKNLDGISHAPNAVK 266
Query: 799 VTQYAASHLVSEARKSQNRPSSE-KVLKNLIYNYKPTYCGYAGKGYDEVYLF 951
Y A V+EARK+ + SE + K LIY + P Y G + + Y+F
Sbjct: 267 TAFYLAEFFVNEARKNNHHFKSESEEEKALIYQFSPIYTGNI-SSFQQCYIF 317
>sp|A7YWG4|GGH_BOVIN Gamma-glutamyl hydrolase OS=Bos taurus GN=GGH PE=2 SV=1
Length = 318
Score = 139 bits (349), Expect = 4e-032
Identities = 80/232 (34%), Positives = 125/232 (53%), Gaps = 8/232 (3%)
Frame = +1
Query: 268 VNGLIFTGGWAK--KYEYFDMVTKIFQKALERNDAGEHFPIYGICLGFELMSIIVSQNRD 441
+NG++F GG + Y + + +++ G++FP++G CLGFE + +VS
Sbjct: 90 INGVLFPGGSVNLMRSGYARVAKMFYNLSIKSFGEGDYFPVWGTCLGFEELIYLVS-GES 148
Query: 442 ILERFDAEDNASSLQFVENVNIEGTLFQRFPPELLRKVSTDCLVMQKHKWGITPEKFKAN 621
+L D L F ++ +FQ FP +LL ++ + L HKW ++ F N
Sbjct: 149 LLTLTDTVGIKLPLNFSRG-TLQSRMFQNFPADLLLSLAVEPLTAHFHKWSLSVMNFTKN 207
Query: 622 HALSSFFEIVTTCIDENSKTYVSTVKAKRYPITGFQWHPEKNAFEWGSSQ-IPHSADAIQ 798
L +FF I+TT D N ++ST++ RYPI G QWHPEK +EWG + I H+ +A++
Sbjct: 208 EKLKAFFSILTTNTDGNI-DFISTMEGYRYPIYGVQWHPEKAPYEWGQLRGISHAPNAVK 266
Query: 799 VTQYAASHLVSEARKSQNRPSSE-KVLKNLIYNYKPTYCGYAGKGYDEVYLF 951
Y A V+EARKS + S+ + K LIY Y+PTY G + + Y+F
Sbjct: 267 AAFYLAEFFVAEARKSNHHFESDVEETKALIYQYRPTYTGNV-SSFQQSYIF 317
>sp|Q62867|GGH_RAT Gamma-glutamyl hydrolase OS=Rattus norvegicus GN=Ggh PE=1
SV=1
Length = 317
Score = 133 bits (333), Expect = 3e-030
Identities = 77/232 (33%), Positives = 130/232 (56%), Gaps = 8/232 (3%)
Frame = +1
Query: 268 VNGLIFTGGWAK-KYEYFDMVTKI-FQKALERNDAGEHFPIYGICLGFELMSIIVSQNRD 441
+NG++ GG A + + V KI F KALE D G++FP++G CLG E +S++VS N +
Sbjct: 89 INGVLLPGGGANLTHSGYSRVAKIFFTKALESFDNGDYFPVWGTCLGLEELSVLVS-NDN 147
Query: 442 ILERFDAEDNASSLQFVENVNIEGTLFQRFPPELLRKVSTDCLVMQKHKWGITPEKFKAN 621
+L + L F + + + +F+ P ELL ++++ L HKW ++ + F N
Sbjct: 148 LLTLTNTSSVKLPLNFTRD-SKQSRMFRNLPEELLNSLASENLTANFHKWSLSVKNFTEN 206
Query: 622 HALSSFFEIVTTCIDENSKTYVSTVKAKRYPITGFQWHPEKNAFEWGSSQ-IPHSADAIQ 798
L FF I+T D ++ ++S+++ +YPI QWHPEK FEW + I H+ +A++
Sbjct: 207 EKLKKFFNILTVNTDGKTE-FISSMEGYKYPIYAVQWHPEKAPFEWKKLRGISHAPNAVK 265
Query: 799 VTQYAASHLVSEARKSQNRPSSE-KVLKNLIYNYKPTYCGYAGKGYDEVYLF 951
+ Y A +SEA K+ + +E + ++LIY + P Y G + + Y+F
Sbjct: 266 TSFYLAKFFISEALKNDHHFENELEETESLIYQFCPVYTGNI-SSFQQAYMF 316
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,801,685,782
Number of Sequences: 518415
Number of Extensions: 36801685782
Number of Successful Extensions: 258262551
Number of sequences better than 0.0: 0
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