BLASTX 7.6.2
Query= UN09267 /QuerySize=1097
(1096 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P45432|CSN1_ARATH COP9 signalosome complex subunit 1 OS=Arabi... 559 1e-158
sp|Q54QX3|CSN1_DICDI COP9 signalosome complex subunit 1 OS=Dicty... 327 1e-088
sp|Q9VVU5|CSN1_DROME COP9 signalosome complex subunit 1b OS=Dros... 294 8e-079
sp|Q6NRT5|CSN1_XENLA COP9 signalosome complex subunit 1 OS=Xenop... 233 2e-060
sp|Q99LD4|CSN1_MOUSE COP9 signalosome complex subunit 1 OS=Mus m... 229 4e-059
sp|Q13098|CSN1_HUMAN COP9 signalosome complex subunit 1 OS=Homo ... 228 5e-059
sp|P97834|CSN1_RAT COP9 signalosome complex subunit 1 OS=Rattus ... 228 9e-059
sp|Q5BD89|CSN1_EMENI COP9 signalosome complex subunit 1 OS=Emeri... 184 9e-046
sp|Q7RXQ1|CSN1_NEUCR COP9 signalosome complex subunit 1 OS=Neuro... 151 8e-036
sp|O94308|CSN1_SCHPO COP9 signalosome complex subunit 1 OS=Schiz... 113 2e-024
sp|Q9GS00|CSN1_CAEEL COP9 signalosome complex subunit 1 OS=Caeno... 105 9e-022
sp|Q06103|RPN7_YEAST 26S proteasome regulatory subunit RPN7 OS=S... 82 6e-015
sp|P68352|CSN1_BRAOL COP9 signalosome complex subunit 1 (Fragmen... 70 2e-011
sp|Q55C75|PSMD6_DICDI 26S proteasome non-ATPase regulatory subun... 68 9e-011
>sp|P45432|CSN1_ARATH COP9 signalosome complex subunit 1 OS=Arabidopsis thaliana
GN=CSN1 PE=1 SV=2
Length = 441
Score = 559 bits (1440), Expect = 1e-158
Identities = 274/296 (92%), Positives = 288/296 (97%)
Frame = +2
Query: 2 DFGDFYYACGLLNDAFKNYVRTRDYCTTAKHIIHMCMNAILVSIEMGQFSHVSSYVNKAE 181
DFGDFYYACG+L DAFKNY+RTRDYCTT KHIIHMCMNAILVSIEMGQF+HV+SYVNKAE
Sbjct: 144 DFGDFYYACGMLGDAFKNYIRTRDYCTTTKHIIHMCMNAILVSIEMGQFTHVTSYVNKAE 203
Query: 182 QNPEALEPIVAAKLRCASGLAHLELKKYKLAARKFLDVSPELGNSYNEVIAPQDVATYGG 361
QNPE LEP+V AKLRCASGLAHLELKKYKLAARKFLDV+PELGNSYNEVIAPQD+ATYGG
Sbjct: 204 QNPETLEPMVNAKLRCASGLAHLELKKYKLAARKFLDVNPELGNSYNEVIAPQDIATYGG 263
Query: 362 LCALASFDRSELKAKVIDNINFRDFLELVPEVRELINDFYSSRYASCLEYLGSLRANLLL 541
LCALASFDRSELK KVIDNINFR+FLELVP+VRELINDFYSSRYASCLEYL SL++NLLL
Sbjct: 264 LCALASFDRSELKQKVIDNINFRNFLELVPDVRELINDFYSSRYASCLEYLASLKSNLLL 323
Query: 542 DIHLHDHVDILYDQIRKKALIQYTLPFVSVDLSRMADAFKTSVSGLEKELEALITDNQIQ 721
DIHLHDHVD LYDQIRKKALIQYTLPFVSVDLSRMADAFKTSVSGLEKELEALITDNQIQ
Sbjct: 324 DIHLHDHVDTLYDQIRKKALIQYTLPFVSVDLSRMADAFKTSVSGLEKELEALITDNQIQ 383
Query: 722 ARIDSHNKILYARHADQRNATFQKVLQMGNEFDRDVRSMMLRANLLKHEYHARAGR 889
ARIDSHNKILYARHADQRNATFQKVLQMGNEFDRDVR+M+LRANLLKHEYHAR+ R
Sbjct: 384 ARIDSHNKILYARHADQRNATFQKVLQMGNEFDRDVRAMLLRANLLKHEYHARSAR 439
>sp|Q54QX3|CSN1_DICDI COP9 signalosome complex subunit 1 OS=Dictyostelium
discoideum GN=csn1 PE=1 SV=1
Length = 458
Score = 327 bits (836), Expect = 1e-088
Identities = 157/296 (53%), Positives = 221/296 (74%), Gaps = 1/296 (0%)
Frame = +2
Query: 2 DFGDFYYACGLLNDAFKNYVRTRDYCTTAKHIIHMCMNAILVSIEMGQFSHVSSYVNKAE 181
D G+FYY G +A K ++RTRDYCTT+KH++ MC N I + ++ ++H SY+ KAE
Sbjct: 133 DLGEFYYKIGDHQNALKCFIRTRDYCTTSKHVLAMCFNIIKLGVDTQNYTHAPSYIAKAE 192
Query: 182 QNPEALEPIVAAKLRCASGLAHLELKKYKLAARKFLDVSPELGNSYNEVIAPQDVATYGG 361
Q+P+ L+ + AKLR +GL +L+ +YKLAARKF++ E N ++++I+PQD+A YGG
Sbjct: 193 QSPD-LDNVSNAKLRSVNGLYNLDGSRYKLAARKFIETPFEQSNVFSDIISPQDIAYYGG 251
Query: 362 LCALASFDRSELKAKVIDNINFRDFLELVPEVRELINDFYSSRYASCLEYLGSLRANLLL 541
LCALA+FDR+ELK KVID+ F+++LELVPE+RELINDFY+++Y SCL+YL ++ LLL
Sbjct: 252 LCALATFDRNELKKKVIDDPMFKNYLELVPELRELINDFYNTKYGSCLKYLDKMKPILLL 311
Query: 542 DIHLHDHVDILYDQIRKKALIQYTLPFVSVDLSRMADAFKTSVSGLEKELEALITDNQIQ 721
DIHL+ HV+ILY +IR KAL+QY P+ SVD++ MA AF T+V+ LEKE+ LI +N+IQ
Sbjct: 312 DIHLYKHVEILYQRIRSKALVQYFSPYQSVDMNIMASAFNTTVTLLEKEISKLIMENEIQ 371
Query: 722 ARIDSHNKILYARHADQRNATFQKVLQMGNEFDRDVRSMMLRANLLKHEYHARAGR 889
ARIDSHNK LYAR ADQR TF+K +Q+G++F S++LR +L + + R
Sbjct: 372 ARIDSHNKRLYARKADQRTTTFEKTVQVGSDFQNSSNSLLLRLEMLNNNISTVSNR 427
>sp|Q9VVU5|CSN1_DROME COP9 signalosome complex subunit 1b OS=Drosophila
melanogaster GN=CSN1b PE=2 SV=1
Length = 525
Score = 294 bits (752), Expect = 8e-079
Identities = 152/309 (49%), Positives = 211/309 (68%), Gaps = 12/309 (3%)
Frame = +2
Query: 2 DFGDFYYACGLLNDAFKNYVRTRDYCTTAKHIIHMCMNAILVSIEMGQFSHVSSYVNKAE 181
D D Y +CG L +A K Y R RDYCT+ KH+++MC+N I VSI + ++HV SY++KAE
Sbjct: 199 DLADHYLSCGDLTNALKCYSRARDYCTSGKHVVNMCLNVIKVSIYLQNWAHVMSYISKAE 258
Query: 182 QNPEALE------PIVAAKLRCASGLAHLELKKYKLAARKFLDVSPELGNSYNEVIAPQD 343
P+ E V +L CA+GLA L+ KKYK+AA+ FL+ + + + E+I+ +
Sbjct: 259 STPDFAEGSKEANAQVHTRLECAAGLAELQQKKYKVAAKHFLNANFD-HCDFPEMISTSN 317
Query: 344 VATYGGLCALASFDRSELKAKVIDNINFRDFLELVPEVRELINDFYSSRYASCLEYLGSL 523
VA YGGLCALA+FDR ELK VI + +F+ FLEL P++R++I FY S+YASCL L +
Sbjct: 318 VAVYGGLCALATFDRQELKRLVIASTSFKLFLELEPQLRDIIFKFYESKYASCLTLLDEI 377
Query: 524 RANLLLDIHLHDHVDILYDQIRKKALIQYTLPFVSVDLSRMADAFKTSVSGLEKELEALI 703
R NLL+D+++ HV LY +IR +ALIQY P++S D+ +MA AF +SV LE E+ LI
Sbjct: 378 RDNLLVDMYIAPHVTTLYTKIRNRALIQYFSPYMSADMHKMAMAFNSSVGDLENEVMQLI 437
Query: 704 TDNQIQARIDSHNKILYARHADQRNATFQKVLQMGNEFDRDVRSMMLRANLLKHEYHARA 883
D QIQARIDSHNKIL+A+ ADQRN+TF++ L MG ++ R R ++LRA +LK H ++
Sbjct: 438 LDGQIQARIDSHNKILFAKEADQRNSTFERALIMGKQYQRHTRMLVLRAAMLKSHIHVKS 497
Query: 884 -----GRNH 895
G NH
Sbjct: 498 ISREGGSNH 506
>sp|Q6NRT5|CSN1_XENLA COP9 signalosome complex subunit 1 OS=Xenopus laevis
GN=csn1 PE=2 SV=1
Length = 487
Score = 233 bits (593), Expect = 2e-060
Identities = 121/225 (53%), Positives = 163/225 (72%), Gaps = 1/225 (0%)
Frame = +2
Query: 209 VAAKLRCASGLAHLELKKYKLAARKFLDVSPELGNSYNEVIAPQDVATYGGLCALASFDR 388
V KL+CA+GLA L +KYK AA+ FL S + + E+++P +VA YGGLCALA+FDR
Sbjct: 241 VLTKLKCAAGLAELAARKYKQAAKCFLLASFD-HCDFPELLSPSNVAVYGGLCALATFDR 299
Query: 389 SELKAKVIDNINFRDFLELVPEVRELINDFYSSRYASCLEYLGSLRANLLLDIHLHDHVD 568
EL+ VI + +F+ FLEL P+VR++I FY S+YASCL+ L ++ NLLLD++L HV
Sbjct: 300 QELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEIKDNLLLDMYLAPHVR 359
Query: 569 ILYDQIRKKALIQYTLPFVSVDLSRMADAFKTSVSGLEKELEALITDNQIQARIDSHNKI 748
LY QIR +ALIQY P+VS D+ +MA AF T+VS LE EL LI + I ARIDSH+KI
Sbjct: 360 TLYTQIRNRALIQYFSPYVSADMYKMATAFNTTVSALEDELTQLILEGLINARIDSHSKI 419
Query: 749 LYARHADQRNATFQKVLQMGNEFDRDVRSMMLRANLLKHEYHARA 883
LYAR DQR+ TF+K LQMG EF R ++M+LRA +L+++ H ++
Sbjct: 420 LYARDVDQRSTTFEKSLQMGREFQRRAKAMILRAAVLRNQIHVKS 464
Score = 84 bits (206), Expect = 2e-015
Identities = 45/97 (46%), Positives = 60/97 (61%), Gaps = 2/97 (2%)
Frame = +2
Query: 2 DFGDFYYACGLLNDAFKNYVRTRDYCTTAKHIIHMCMNAILVSIEMGQFSHVSSYVNKAE 181
D GD Y CG L++A K Y R RDYCT+AKH+I+MC+N I VS+ + +SHV SYV+KAE
Sbjct: 163 DLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAE 222
Query: 182 QNPEALEPIVAAKLRCASGLAHLELKK--YKLAARKF 286
PE E + + L L+ +LAARK+
Sbjct: 223 STPEIAEQRGERDSQTQAVLTKLKCAAGLAELAARKY 259
>sp|Q99LD4|CSN1_MOUSE COP9 signalosome complex subunit 1 OS=Mus musculus GN=Gps1
PE=1 SV=1
Length = 471
Score = 229 bits (582), Expect = 4e-059
Identities = 118/225 (52%), Positives = 162/225 (72%), Gaps = 1/225 (0%)
Frame = +2
Query: 209 VAAKLRCASGLAHLELKKYKLAARKFLDVSPELGNSYNEVIAPQDVATYGGLCALASFDR 388
+ KL+CA+GLA L +KYK AA+ FL S + + E+++P +VA YGGLCALA+FDR
Sbjct: 225 ILTKLKCAAGLAELAARKYKQAAKCFLLASFD-HCDFPELLSPSNVAVYGGLCALATFDR 283
Query: 389 SELKAKVIDNINFRDFLELVPEVRELINDFYSSRYASCLEYLGSLRANLLLDIHLHDHVD 568
EL+ VI + +F+ FLEL P+VR++I FY S+YASCL+ L ++ NLLLD++L HV
Sbjct: 284 QELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVR 343
Query: 569 ILYDQIRKKALIQYTLPFVSVDLSRMADAFKTSVSGLEKELEALITDNQIQARIDSHNKI 748
LY QIR +ALIQY P+VS D+ +MA AF T+V+ LE EL LI + I ARIDSH+KI
Sbjct: 344 TLYTQIRNRALIQYFSPYVSADMHKMAAAFNTTVAALEDELTQLILEGLINARIDSHSKI 403
Query: 749 LYARHADQRNATFQKVLQMGNEFDRDVRSMMLRANLLKHEYHARA 883
LYAR DQR+ TF+K L MG EF R ++M+LRA +L+++ H ++
Sbjct: 404 LYARDVDQRSTTFEKSLLMGKEFQRRAKAMILRAAVLRNQIHVKS 448
Score = 84 bits (205), Expect = 2e-015
Identities = 38/67 (56%), Positives = 48/67 (71%)
Frame = +2
Query: 2 DFGDFYYACGLLNDAFKNYVRTRDYCTTAKHIIHMCMNAILVSIEMGQFSHVSSYVNKAE 181
D GD Y CG L++A K Y R RDYCT+AKH+I+MC+N I VS+ + +SHV SYV+KAE
Sbjct: 147 DLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAE 206
Query: 182 QNPEALE 202
PE E
Sbjct: 207 STPEIAE 213
>sp|Q13098|CSN1_HUMAN COP9 signalosome complex subunit 1 OS=Homo sapiens GN=GPS1
PE=1 SV=4
Length = 491
Score = 228 bits (581), Expect = 5e-059
Identities = 118/225 (52%), Positives = 161/225 (71%), Gaps = 1/225 (0%)
Frame = +2
Query: 209 VAAKLRCASGLAHLELKKYKLAARKFLDVSPELGNSYNEVIAPQDVATYGGLCALASFDR 388
+ KL+CA+GLA L +KYK AA+ L S + + E+++P +VA YGGLCALA+FDR
Sbjct: 245 ILTKLKCAAGLAELAARKYKQAAKCLLLASFD-HCDFPELLSPSNVAIYGGLCALATFDR 303
Query: 389 SELKAKVIDNINFRDFLELVPEVRELINDFYSSRYASCLEYLGSLRANLLLDIHLHDHVD 568
EL+ VI + +F+ FLEL P+VR++I FY S+YASCL+ L ++ NLLLD++L HV
Sbjct: 304 QELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVR 363
Query: 569 ILYDQIRKKALIQYTLPFVSVDLSRMADAFKTSVSGLEKELEALITDNQIQARIDSHNKI 748
LY QIR +ALIQY P+VS D+ RMA AF T+V+ LE EL LI + I AR+DSH+KI
Sbjct: 364 TLYTQIRNRALIQYFSPYVSADMHRMAAAFNTTVAALEDELTQLILEGLISARVDSHSKI 423
Query: 749 LYARHADQRNATFQKVLQMGNEFDRDVRSMMLRANLLKHEYHARA 883
LYAR DQR+ TF+K L MG EF R ++MMLRA +L+++ H ++
Sbjct: 424 LYARDVDQRSTTFEKSLLMGKEFQRRAKAMMLRAAVLRNQIHVKS 468
Score = 84 bits (205), Expect = 2e-015
Identities = 38/67 (56%), Positives = 48/67 (71%)
Frame = +2
Query: 2 DFGDFYYACGLLNDAFKNYVRTRDYCTTAKHIIHMCMNAILVSIEMGQFSHVSSYVNKAE 181
D GD Y CG L++A K Y R RDYCT+AKH+I+MC+N I VS+ + +SHV SYV+KAE
Sbjct: 167 DLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAE 226
Query: 182 QNPEALE 202
PE E
Sbjct: 227 STPEIAE 233
>sp|P97834|CSN1_RAT COP9 signalosome complex subunit 1 OS=Rattus norvegicus
GN=Gps1 PE=1 SV=1
Length = 471
Score = 228 bits (579), Expect = 9e-059
Identities = 117/225 (52%), Positives = 162/225 (72%), Gaps = 1/225 (0%)
Frame = +2
Query: 209 VAAKLRCASGLAHLELKKYKLAARKFLDVSPELGNSYNEVIAPQDVATYGGLCALASFDR 388
+ KL+CA+GLA L +KYK AA+ FL S + + E+++P +VA YGGLCALA+FDR
Sbjct: 225 ILTKLKCAAGLAELAARKYKQAAKCFLLASFD-HCDFPELLSPSNVAVYGGLCALATFDR 283
Query: 389 SELKAKVIDNINFRDFLELVPEVRELINDFYSSRYASCLEYLGSLRANLLLDIHLHDHVD 568
EL+ VI + +F+ FLEL P+VR++I FY S+YASCL+ L ++ NLLLD++L HV
Sbjct: 284 QELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVR 343
Query: 569 ILYDQIRKKALIQYTLPFVSVDLSRMADAFKTSVSGLEKELEALITDNQIQARIDSHNKI 748
LY QIR +ALIQY P+VS D+ +MA AF T+V+ LE EL +I + I ARIDSH+KI
Sbjct: 344 TLYTQIRNRALIQYFSPYVSADMHKMAAAFNTTVAALEDELTQVILEGLINARIDSHSKI 403
Query: 749 LYARHADQRNATFQKVLQMGNEFDRDVRSMMLRANLLKHEYHARA 883
LYAR DQR+ TF+K L MG EF R ++M+LRA +L+++ H ++
Sbjct: 404 LYARDVDQRSTTFEKSLLMGKEFQRRAKAMILRAAVLRNQIHVKS 448
Score = 84 bits (205), Expect = 2e-015
Identities = 38/67 (56%), Positives = 48/67 (71%)
Frame = +2
Query: 2 DFGDFYYACGLLNDAFKNYVRTRDYCTTAKHIIHMCMNAILVSIEMGQFSHVSSYVNKAE 181
D GD Y CG L++A K Y R RDYCT+AKH+I+MC+N I VS+ + +SHV SYV+KAE
Sbjct: 147 DLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAE 206
Query: 182 QNPEALE 202
PE E
Sbjct: 207 STPEIAE 213
>sp|Q5BD89|CSN1_EMENI COP9 signalosome complex subunit 1 OS=Emericella nidulans
GN=csnA PE=1 SV=2
Length = 498
Score = 184 bits (467), Expect = 9e-046
Identities = 100/220 (45%), Positives = 134/220 (60%), Gaps = 4/220 (1%)
Frame = +2
Query: 8 GDFYYACGLLNDAFKNYVRTRDYCTTAKHIIHMCMNAILVSIEMGQFSHVSSYVNKAEQ- 184
G Y+ G L AFK Y R RD+CTT HI M I V+IE G + +V S V++
Sbjct: 163 GQHYHRIGDLTSAFKAYSRMRDFCTTPSHIASMLFKIINVAIERGDWLNVQSNVHRLRSQ 222
Query: 185 --NPEALEPIVAAKLRCASGLAHLELKKYKLAARKFLDVSPELGNSYNEVIAPQDVATYG 358
PE + K+ A GL+ L Y AA F+ P LG+++NEV+ DVA YG
Sbjct: 223 GGKPEE-QAKHQPKISAAMGLSQLHSGSYLEAANSFIATDPSLGDTFNEVLTSNDVAVYG 281
Query: 359 GLCALASFDRSELKAKVIDNINFRDFLELVPEVRELINDFYSSRYASCLEYLGSLRANLL 538
GLCALAS DR+EL+ +V+DN +FR+FLEL P +R I+ F +S++ CLE L + RA+ L
Sbjct: 282 GLCALASMDRNELQRRVLDNSSFRNFLELEPHIRRAISFFCNSKFRPCLEILEAYRADYL 341
Query: 539 LDIHLHDHVDILYDQIRKKALIQYTLPFVSVDLSRMADAF 658
LDIHL HV +LY++IR K++ QY +PF V L MA F
Sbjct: 342 LDIHLQRHVQVLYNRIRTKSIQQYLIPFNRVSLESMAKIF 381
>sp|Q7RXQ1|CSN1_NEUCR COP9 signalosome complex subunit 1 OS=Neurospora crassa
GN=csn-1 PE=1 SV=1
Length = 425
Score = 151 bits (381), Expect = 8e-036
Identities = 91/253 (35%), Positives = 144/253 (56%), Gaps = 17/253 (6%)
Frame = +2
Query: 17 YYACGLLNDAFKNYVRTRDYCTTAKHIIHMCMNAILVSIEMGQFSHVSSY------VNKA 178
+ A G + A ++ + R ++ + ++ + + V+IE + + ++ VN +
Sbjct: 125 FEAIGDVEAAMDSFWKMRTEVSSTEQLVDLGKLLVRVAIERRDWKSIGNHLKPLNSVNDS 184
Query: 179 EQNPEALEPIVAAKLRCASGLAHLELKKYKLAARKFLDVS----PELGNSYNEVIAPQDV 346
+ +AL+ + A+G+A L ++YK AA F++ S PE+ YN++ +P DV
Sbjct: 185 DPKAKALK----TYSKIANGIAALGQERYKEAAFCFVEASSGVPPEI---YNQIASPNDV 237
Query: 347 ATYGGLCALASFDRSELKAKVIDNINFRDFLELVPEVRELINDFYSSRYASCLEYLGSLR 526
A YGGL ALA+ DR EL+A ++DN +FR+FL+ P +R I F + RYA+C+E L S R
Sbjct: 238 AIYGGLLALATMDRHELQANLLDNDSFREFLQREPHIRRAITQFVNGRYAACIEILESYR 297
Query: 527 ANLLLDIHLHDHVDILYDQIRKKALIQYTLPFVSVDLSRMADAFKTSVSGLEKELEALIT 706
+ LLDI+L HV LY IR K+++QY PF V L M AF +E EL +I
Sbjct: 298 PDYLLDIYLQKHVPKLYADIRTKSIVQYLKPFSCVRLDTMQKAFNGPGPSIEDELFTMIK 357
Query: 707 DNQIQARIDSHNK 745
D ++ ARID+ NK
Sbjct: 358 DGKLNARIDAINK 370
>sp|O94308|CSN1_SCHPO COP9 signalosome complex subunit 1 OS=Schizosaccharomyces
pombe GN=csn1 PE=1 SV=1
Length = 422
Score = 113 bits (282), Expect = 2e-024
Identities = 67/251 (26%), Positives = 127/251 (50%), Gaps = 4/251 (1%)
Frame = +2
Query: 2 DFGDFYYACGLLNDAFKNYVRTRDYCTTAKHIIHMCMNAILVSIEMGQFSHVSSYVNKAE 181
D F+ G + A ++Y + R+YCT A I H+ + + +SI +G +SHV ++ ++A+
Sbjct: 117 DLASFFADVGQFDSALRSYAKVREYCTNAGQIAHLSLELMRISIWIGNYSHVLAFGSRAK 176
Query: 182 QNPEALEPIVAAKLRCASGLAHLELKKYKLAARKFLDVSPELGNSYNEVIAPQDVATYGG 361
A + + + GLA+ L Y+ A FL V + + +I D++ Y
Sbjct: 177 STVSAAMEL-TSPIYAYCGLANFCLGDYEEALAHFLKVETDTSDG---IITKTDISVYIS 232
Query: 362 LCALASFDRSELKAKVIDNINFRDFLELVPEVRELINDFYSSRYASCLEYLGSLRANLLL 541
LCALA +D L ++ N F +L P +R + + +Y+ L+ L + L
Sbjct: 233 LCALACWDHKRLIQELERNEEFNALSDLDPSLRRCLQAKCNRKYSLLLDTLQQNAQDYSL 292
Query: 542 DIHLHDHVDILYDQIRKKALIQYTLPFVSVDLSRMADAFKTSVSGLEKELEALITDNQIQ 721
D++L + L+ IR+++L+ Y +P+ ++ S++A F + +EK L +I ++
Sbjct: 293 DMYLAPQLTNLFSLIRERSLLDYLIPYSALPFSKIAVDFHIDENFIEKNLLEIIEAKKLN 352
Query: 722 ARIDSHNKILY 754
++DS K +Y
Sbjct: 353 GKVDSLQKRVY 363
>sp|Q9GS00|CSN1_CAEEL COP9 signalosome complex subunit 1 OS=Caenorhabditis
elegans GN=csn-1 PE=1 SV=1
Length = 601
Score = 105 bits (260), Expect = 9e-022
Identities = 64/221 (28%), Positives = 110/221 (49%), Gaps = 1/221 (0%)
Frame = +2
Query: 215 AKLRCASGLAHLELKKYKLAARKFLDVSPELGNSYNEVIAPQDVATYGGLCALASFDRSE 394
AK A L L K+Y L + E S + D+ YG L A+A+ R++
Sbjct: 316 AKCLAAQVLLKLRNKRYSQVVETILQIKTECLQS-KWFVTSSDLGIYGMLSAMATMSRAD 374
Query: 395 LKAKVIDNINFRDFLELVPEVRELINDFYSSRYASCLEYLGSLRANLLLDIHLHDHVDIL 574
LK +V N FR LE P++ EL+ + SSR+ C E + S++ LLLD + +VD L
Sbjct: 375 LKLQVSGNGTFRKLLESEPQLIELLGSYTSSRFGRCFEIMRSVKPRLLLDPFISRNVDEL 434
Query: 575 YDQIRKKALIQYTLPFVSVDLSRMADAFKTSVSGLEKELEALITDNQIQARIDSHNKILY 754
+++IR+K ++QY P+ ++ ++ MA+A S + L+ L LI + +ID + I+
Sbjct: 435 FEKIRQKCVLQYLQPYSTIKMATMAEAVGMSSAELQLSLLELIEQKHVSLKIDQNEGIVR 494
Query: 755 ARHADQRNATFQKVLQMGNEFDRDVRSMMLRANLLKHEYHA 877
NA ++V + + +S++ + L H+
Sbjct: 495 ILDERDENAILKRVNVTCDRATQKAKSLLWKTTLAGANIHS 535
>sp|Q06103|RPN7_YEAST 26S proteasome regulatory subunit RPN7 OS=Saccharomyces
cerevisiae GN=RPN7 PE=1 SV=3
Length = 429
Score = 82 bits (201), Expect = 6e-015
Identities = 54/196 (27%), Positives = 98/196 (50%), Gaps = 6/196 (3%)
Frame = +2
Query: 236 GLAHLELKKYKLAARKFLDVSPELGNSYNEVIAPQDVATYGGLCALASFDRSELKAKVID 415
G+ L ++ +K AA+ +D + E+ + + +ATY + L + +R++LK+KVID
Sbjct: 215 GIHCLAVRNFKEAAKLLVDSLATFTSI--ELTSYESIATYASVTGLFTLERTDLKSKVID 272
Query: 416 NINFRDFLE---LVPEVRELINDFYSSRYASCLEYLGSLRANLLLDI-HLHDHVDILYDQ 583
+ + + + L Y+S YAS YL AN+L+ +L+ H D +
Sbjct: 273 SPELLSLISTTAALQSISSLTISLYASDYASYFPYLLETYANVLIPCKYLNRHADFFVRE 332
Query: 584 IRKKALIQYTLPFVSVDLSRMADAFKTSVSGLEKELEALITDNQIQARIDSHNKILYARH 763
+R+K Q + ++ L MA AF SV+ L+ +L I + Q+ ID N I+
Sbjct: 333 MRRKVYAQLLESYKTLSLKSMASAFGVSVAFLDNDLGKFIPNKQLNCVIDRVNGIVETNR 392
Query: 764 ADQRNATFQKVLQMGN 811
D +NA + +++ G+
Sbjct: 393 PDNKNAQYHLLVKQGD 408
>sp|P68352|CSN1_BRAOL COP9 signalosome complex subunit 1 (Fragment) OS=Brassica
oleracea GN=CSN1 PE=1 SV=1
Length = 37
Score = 70 bits (170), Expect = 2e-011
Identities = 36/37 (97%), Gaps = 1/37 (2%)
Frame = +2
Query: 686 ELEA-LITDNQIQARIDSHNKILYARHADQRNATFQK 793
ELEA LITDNQIQARIDSHNKILYARHADQRNATFQK
Sbjct: 1 ELEALLITDNQIQARIDSHNKILYARHADQRNATFQK 37
>sp|Q55C75|PSMD6_DICDI 26S proteasome non-ATPase regulatory subunit 6
OS=Dictyostelium discoideum GN=psmD6 PE=1 SV=1
Length = 382
Score = 68 bits (165), Expect = 9e-011
Identities = 45/207 (21%), Positives = 96/207 (46%), Gaps = 2/207 (0%)
Frame = +2
Query: 218 KLRCASGLAHLELKKYKLAARKFLDVSPELGNSYNEVIAPQDVATYGGLCALASFDRSEL 397
+L+ + + ++++K A+ +L+ ++ E I Y +L DR L
Sbjct: 172 RLKTYEAVYKMSIRQFKEASDLYLETVASFTST--EFIDYSRFIQYLIFTSLLHLDRVSL 229
Query: 398 KAKVIDNINFRDFLELVPEVRELINDFYSSRYASCLEYLGSLRANLLLDIHLHDHVDILY 577
K KVID+ + + P++++L+ FY+ YA+ L ++ D +L +H
Sbjct: 230 KQKVIDSPDVLSVINDTPKLQDLLQSFYNGDYANFFGALAHFSDSIKGDRYLAEHSRFFT 289
Query: 578 DQIRKKALIQYTLPFVSVDLSRMADAFKTSVSGLEKELEALITDNQIQARIDSHNKILYA 757
++R A Q+ + SV L M++ F S +++EL + ++ +ID + ++
Sbjct: 290 REMRILAYNQFLESYSSVKLESMSNQFGVSYDFIDRELSRFVAAGRLNCKIDKVSGVIET 349
Query: 758 RHADQRNATFQKVLQMGNEFDRDVRSM 838
+D +N ++ LQ G+ V+ +
Sbjct: 350 TRSDAKNHLYKTTLQQGDNLLNRVQKL 376
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,801,685,782
Number of Sequences: 518415
Number of Extensions: 36801685782
Number of Successful Extensions: 258262551
Number of sequences better than 0.0: 0
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