BLASTX 7.6.2
Query= UN09724 /QuerySize=1192
(1191 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P54001|P4HA1_RAT Prolyl 4-hydroxylase subunit alpha-1 OS=Ratt... 105 1e-021
sp|Q5ZLK5|P4HA2_CHICK Prolyl 4-hydroxylase subunit alpha-2 OS=Ga... 104 1e-021
sp|O15460|P4HA2_HUMAN Prolyl 4-hydroxylase subunit alpha-2 OS=Ho... 102 5e-021
sp|Q60715|P4HA1_MOUSE Prolyl 4-hydroxylase subunit alpha-1 OS=Mu... 102 6e-021
sp|Q60716|P4HA2_MOUSE Prolyl 4-hydroxylase subunit alpha-2 OS=Mu... 102 8e-021
sp|P16924|P4HA1_CHICK Prolyl 4-hydroxylase subunit alpha-1 OS=Ga... 101 1e-020
sp|P13674|P4HA1_HUMAN Prolyl 4-hydroxylase subunit alpha-1 OS=Ho... 99 4e-020
sp|Q5RAG8|P4HA1_PONAB Prolyl 4-hydroxylase subunit alpha-1 OS=Po... 99 4e-020
sp|Q10576|P4HA1_CAEEL Prolyl 4-hydroxylase subunit alpha-1 OS=Ca... 97 2e-019
sp|Q1RMU3|P4HA1_BOVIN Prolyl 4-hydroxylase subunit alpha-1 OS=Bo... 97 3e-019
>sp|P54001|P4HA1_RAT Prolyl 4-hydroxylase subunit alpha-1 OS=Rattus norvegicus
GN=P4ha1 PE=2 SV=2
Length = 534
Score = 105 bits (260), Expect = 1e-021
Identities = 57/142 (40%), Positives = 80/142 (56%), Gaps = 4/142 (2%)
Frame = +2
Query: 332 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDHV 511
+PR + +H+ +++ E E + LAKP + ++TV D +TG ++ R S +L D V
Sbjct: 334 KPRIIRFHDIISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYEDPV 393
Query: 512 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFL----DEFNTKNGGQRIATV 679
V RI RI D T + V E LQV +Y VG +YEPH+D+ D F G RIAT
Sbjct: 394 VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATW 453
Query: 680 LMYLSDVDDGGETVFPAAKGNI 745
L Y+SDV GG TVFP ++
Sbjct: 454 LFYMSDVSAGGATVFPEVGASV 475
>sp|Q5ZLK5|P4HA2_CHICK Prolyl 4-hydroxylase subunit alpha-2 OS=Gallus gallus
GN=P4HA2 PE=2 SV=1
Length = 534
Score = 104 bits (259), Expect = 1e-021
Identities = 55/136 (40%), Positives = 85/136 (62%), Gaps = 3/136 (2%)
Frame = +2
Query: 329 WE-PRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHD 505
W+ P V Y++ +++EE E + LAKP + ++TV D KTG + R S ++L+ D
Sbjct: 334 WDSPHIVRYYDVMSDEEIEKIKQLAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDD 393
Query: 506 HVVERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFLDEFNT--KNGGQRIATV 679
VV ++ QR+ T + V+ E LQV +Y +G +YEPH+D+ F++ K+ G R+AT
Sbjct: 394 PVVAKVNQRMQQITGLTVKTAELLQVANYGMGGQYEPHFDFSRRPFDSTLKSEGNRLATF 453
Query: 680 LMYLSDVDDGGETVFP 727
L Y+SDV+ GG TVFP
Sbjct: 454 LNYMSDVEAGGATVFP 469
>sp|O15460|P4HA2_HUMAN Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens
GN=P4HA2 PE=1 SV=1
Length = 535
Score = 102 bits (254), Expect = 5e-021
Identities = 55/138 (39%), Positives = 82/138 (59%), Gaps = 5/138 (3%)
Frame = +2
Query: 329 WE-PRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHD 505
W+ P V Y++ +++EE E + +AKP + ++TV D KTG + R S ++L+ D
Sbjct: 333 WDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDD 392
Query: 506 HVVERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYF----LDEFNTKNGGQRIA 673
VV R+ +R+ T + V+ E LQV +Y VG +YEPH+D+ D F G R+A
Sbjct: 393 PVVARVNRRMQHITGLTVKTAELLQVANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVA 452
Query: 674 TVLMYLSDVDDGGETVFP 727
T L Y+SDV+ GG TVFP
Sbjct: 453 TFLNYMSDVEAGGATVFP 470
>sp|Q60715|P4HA1_MOUSE Prolyl 4-hydroxylase subunit alpha-1 OS=Mus musculus
GN=P4ha1 PE=2 SV=2
Length = 534
Score = 102 bits (253), Expect = 6e-021
Identities = 58/154 (37%), Positives = 84/154 (54%), Gaps = 9/154 (5%)
Frame = +2
Query: 332 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDHV 511
+PR + +H+ +++ E E + LAKP + ++T+ + TG + R S +L D V
Sbjct: 334 KPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPVTGALETVHYRISKSAWLSGYEDPV 393
Query: 512 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFL----DEFNTKNGGQRIATV 679
V RI RI D T + V E LQV +Y VG +YEPH+D+ D F G RIAT
Sbjct: 394 VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATW 453
Query: 680 LMYLSDVDDGGETVFPAAKGNI-----SAVPWWD 766
L Y+SDV GG TVFP ++ +AV W++
Sbjct: 454 LFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYN 487
>sp|Q60716|P4HA2_MOUSE Prolyl 4-hydroxylase subunit alpha-2 OS=Mus musculus
GN=P4ha2 PE=2 SV=1
Length = 537
Score = 102 bits (252), Expect = 8e-021
Identities = 54/138 (39%), Positives = 82/138 (59%), Gaps = 5/138 (3%)
Frame = +2
Query: 329 WE-PRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHD 505
W+ P V Y++ +++EE E + +AKP + ++TV D KTG + R S ++L+ D
Sbjct: 335 WDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDD 394
Query: 506 HVVERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFL----DEFNTKNGGQRIA 673
VV R+ +R+ T + V+ E LQV +Y +G +YEPH+D+ D F G R+A
Sbjct: 395 PVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDDEDAFKRLGTGNRVA 454
Query: 674 TVLMYLSDVDDGGETVFP 727
T L Y+SDV+ GG TVFP
Sbjct: 455 TFLNYMSDVEAGGATVFP 472
>sp|P16924|P4HA1_CHICK Prolyl 4-hydroxylase subunit alpha-1 OS=Gallus gallus
GN=P4HA1 PE=1 SV=1
Length = 516
Score = 101 bits (251), Expect = 1e-020
Identities = 60/154 (38%), Positives = 84/154 (54%), Gaps = 9/154 (5%)
Frame = +2
Query: 332 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDHV 511
+PR V + + +++EE E + LAKP + ++TV D +TG + R S +L V
Sbjct: 316 KPRIVRFLDIISDEEIETVKELAKPRLSRATVHDPETGKLTTAHYRVSKSAWLSGYESPV 375
Query: 512 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFL----DEFNTKNGGQRIATV 679
V RI RI D T + V E LQV +Y VG +YEPH+D+ D F G RIAT
Sbjct: 376 VSRINTRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATW 435
Query: 680 LMYLSDVDDGGETVFPAAKGNI-----SAVPWWD 766
L Y+SDV GG TVFP ++ +AV W++
Sbjct: 436 LFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYN 469
Score = 54 bits (128), Expect = 2e-006
Identities = 23/47 (48%), Positives = 29/47 (61%)
Frame = +2
Query: 791 GLSVLPKKRDALLFWNMRPDASLDPSSLHGGCPVVKGNKWSSTKWFH 931
G SV PKK A+ ++N+ P D S+ H CPV+ GNKW S KW H
Sbjct: 454 GASVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWLH 500
>sp|P13674|P4HA1_HUMAN Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens
GN=P4HA1 PE=1 SV=2
Length = 534
Score = 99 bits (246), Expect = 4e-020
Identities = 57/154 (37%), Positives = 84/154 (54%), Gaps = 9/154 (5%)
Frame = +2
Query: 332 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDHV 511
+PR + +H+ +++ E E + LAKP + ++T+ + TG + R S +L + V
Sbjct: 334 KPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPITGDLETVHYRISKSAWLSGYENPV 393
Query: 512 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFL----DEFNTKNGGQRIATV 679
V RI RI D T + V E LQV +Y VG +YEPH+D+ D F G RIAT
Sbjct: 394 VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATW 453
Query: 680 LMYLSDVDDGGETVFPAAKGNI-----SAVPWWD 766
L Y+SDV GG TVFP ++ +AV W++
Sbjct: 454 LFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYN 487
>sp|Q5RAG8|P4HA1_PONAB Prolyl 4-hydroxylase subunit alpha-1 OS=Pongo abelii
GN=P4HA1 PE=2 SV=1
Length = 534
Score = 99 bits (246), Expect = 4e-020
Identities = 57/154 (37%), Positives = 84/154 (54%), Gaps = 9/154 (5%)
Frame = +2
Query: 332 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDHV 511
+PR + +H+ +++ E E + LAKP + ++T+ + TG + R S +L + V
Sbjct: 334 KPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPITGDLETVHYRISKSAWLSGYENPV 393
Query: 512 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFL----DEFNTKNGGQRIATV 679
V RI RI D T + V E LQV +Y VG +YEPH+D+ D F G RIAT
Sbjct: 394 VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATW 453
Query: 680 LMYLSDVDDGGETVFPAAKGNI-----SAVPWWD 766
L Y+SDV GG TVFP ++ +AV W++
Sbjct: 454 LFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYN 487
>sp|Q10576|P4HA1_CAEEL Prolyl 4-hydroxylase subunit alpha-1 OS=Caenorhabditis
elegans GN=dpy-18 PE=1 SV=2
Length = 559
Score = 97 bits (241), Expect = 2e-019
Identities = 54/148 (36%), Positives = 81/148 (54%), Gaps = 4/148 (2%)
Frame = +2
Query: 314 VEVISWEPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLK 493
VE+ + P AV++ + ++++E + LAKP + ++TV D TG + R S +LK
Sbjct: 321 VEIKRFNPLAVLFKDVISDDEVAAIQELAKPKLARATVHDSVTGKLVTATYRISKSAWLK 380
Query: 494 RGHDHVVERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFLDE----FNTKNGG 661
VVE + +RI T + +E E LQ+ +Y +G Y+PH+D+ E F + G
Sbjct: 381 EWEGDVVETVNKRIGYMTNLEMETAEELQIANYGIGGHYDPHFDHAKKEESKSFESLGTG 440
Query: 662 QRIATVLMYLSDVDDGGETVFPAAKGNI 745
RIATVL Y+S GG TVF AK I
Sbjct: 441 NRIATVLFYMSQPSHGGGTVFTEAKSTI 468
>sp|Q1RMU3|P4HA1_BOVIN Prolyl 4-hydroxylase subunit alpha-1 OS=Bos taurus
GN=P4HA1 PE=1 SV=1
Length = 534
Score = 97 bits (239), Expect = 3e-019
Identities = 54/142 (38%), Positives = 78/142 (54%), Gaps = 4/142 (2%)
Frame = +2
Query: 332 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDHV 511
+PR + +H+ +++ E E + LAKP + ++T+ + TG + R S +L + V
Sbjct: 334 KPRIIRFHDIISDAEIEVVKDLAKPRLRRATISNPITGDLETVHYRISKSAWLSGYENPV 393
Query: 512 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFL----DEFNTKNGGQRIATV 679
V RI RI D T + V E LQV +Y VG +YEPH+D+ D F G RIAT
Sbjct: 394 VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATW 453
Query: 680 LMYLSDVDDGGETVFPAAKGNI 745
L Y+SDV GG TVFP ++
Sbjct: 454 LFYMSDVLAGGATVFPEVGASV 475
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,366,676,449
Number of Sequences: 518415
Number of Extensions: 41366676449
Number of Successful Extensions: 294470065
Number of sequences better than 0.0: 0
|
