BLASTX 7.6.2
Query= UN09821 /QuerySize=1334
(1333 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q94JS4|SMT3B_ARATH 24-methylenesterol C-methyltransferase 3 O... 683 8e-196
sp|Q39227|SMT2_ARATH 24-methylenesterol C-methyltransferase 2 OS... 638 4e-182
sp|O82427|SMT2_ORYSJ 24-methylenesterol C-methyltransferase 2 OS... 514 8e-145
sp|Q6ZIX2|SMT1_ORYSJ Cycloartenol-C-24-methyltransferase 1 OS=Or... 228 1e-058
sp|Q9LM02|SMT1_ARATH Cycloartenol-C-24-methyltransferase OS=Arab... 226 4e-058
sp|Q54I98|SMT1_DICDI Probable cycloartenol-C-24-methyltransferas... 216 4e-055
sp|Q5EN22|ERG6_MAGGR Sterol 24-C-methyltransferase OS=Magnaporth... 212 5e-054
sp|Q96WX4|ERG6_PNECA Sterol 24-C-methyltransferase OS=Pneumocyst... 212 5e-054
sp|Q6C2D9|ERG6_YARLI Sterol 24-C-methyltransferase OS=Yarrowia l... 210 2e-053
sp|Q6CYB3|ERG6_KLULA Sterol 24-C-methyltransferase OS=Kluyveromy... 209 6e-053
sp|Q6BRB7|ERG6_DEBHA Sterol 24-C-methyltransferase OS=Debaryomyc... 208 1e-052
sp|O74198|ERG6_CANAL Sterol 24-C-methyltransferase OS=Candida al... 206 5e-052
sp|O14321|ERG6_SCHPO Sterol 24-C-methyltransferase OS=Schizosacc... 206 5e-052
sp|Q6FRZ7|ERG6_CANGA Sterol 24-C-methyltransferase OS=Candida gl... 205 6e-052
sp|Q875K1|ERG6_CLAL4 Sterol 24-C-methyltransferase OS=Clavispora... 204 2e-051
sp|P25087|ERG6_YEAST Sterol 24-C-methyltransferase OS=Saccharomy... 204 2e-051
sp|Q9P3R1|ERG6_NEUCR Sterol 24-C-methyltransferase OS=Neurospora... 203 2e-051
sp|Q759S7|ERG6_ASHGO Sterol 24-C-methyltransferase OS=Ashbya gos... 193 3e-048
sp|Q9C6B9|PEAM3_ARATH Putative phosphoethanolamine N-methyltrans... 63 5e-009
sp|Q9FR44|PEAM1_ARATH Phosphoethanolamine N-methyltransferase 1 ... 60 3e-008
>sp|Q94JS4|SMT3B_ARATH 24-methylenesterol C-methyltransferase 3 OS=Arabidopsis
thaliana GN=SMT3 PE=2 SV=1
Length = 359
Score = 683 bits (1762), Expect = 8e-196
Identities = 321/359 (89%), Positives = 345/359 (96%)
Frame = -1
Query: 1261 MDNVALYCTAALVAGGIYWFICILGPAERKGKRASDLSGGSISAENVKDNYNQYWSFFRK 1082
MD+VALYCTA L+AG +YWFIC+LGPAERKGKRASDLSGGSISAE VKDNYNQYWSFFRK
Sbjct: 1 MDSVALYCTAGLIAGAVYWFICVLGPAERKGKRASDLSGGSISAEKVKDNYNQYWSFFRK 60
Query: 1081 PKEIESPEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIPGKSDKEATRIHEEMAVDLIK 902
PKEIES EKVPDFVDTFYNLVTDIYEWGWGQSFHFSP +PGKSDK+ATRIHEEMAVDLIK
Sbjct: 61 PKEIESAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPHVPGKSDKDATRIHEEMAVDLIK 120
Query: 901 VKPGQKILDAGCGVGGPMRAIAAHSKAHVVGITINDYQVKRAKEHNKKAGLDSLCDVVYG 722
VKPGQKILDAGCGVGGPMRAIAAHSKA V GITIN+YQV+RAK HNKKAGLDSLC+VV G
Sbjct: 121 VKPGQKILDAGCGVGGPMRAIAAHSKAQVTGITINEYQVQRAKLHNKKAGLDSLCNVVCG 180
Query: 721 NFLEMPSDENTFDGAYSIEATCHAPKLEEVYAEIFRVMKPGSLYVSYEWVTTDKYNDDDQ 542
NFL+MP DENTFDGAYSIEATCHAPKLEEVY+EIFRVMKPGSL+VSYEWVTT+KY DDD+
Sbjct: 181 NFLKMPFDENTFDGAYSIEATCHAPKLEEVYSEIFRVMKPGSLFVSYEWVTTEKYRDDDE 240
Query: 541 EHKEVIQGIERGDALPGLRSYSDIATTAKKVGFEIVDERDLAMPPAKPWWSRLKMGRVAY 362
EHK+VIQGIERGDALPGLRSY+DIA TAKKVGFE+V E+DLA PP+KPWW+RLKMGR+AY
Sbjct: 241 EHKDVIQGIERGDALPGLRSYADIAVTAKKVGFEVVKEKDLAKPPSKPWWNRLKMGRIAY 300
Query: 361 WRNHVVVVVLSAIGVAPKGTVDVHEMLFKTADYLTRGGETGIFSPMHMILCRKPEKSSE 185
WRNHVVVV+LSAIGVAPKGTVDVH+MLFKTADYLTRGGETGIFSPMHMILCRKPEK+SE
Sbjct: 301 WRNHVVVVILSAIGVAPKGTVDVHKMLFKTADYLTRGGETGIFSPMHMILCRKPEKASE 359
>sp|Q39227|SMT2_ARATH 24-methylenesterol C-methyltransferase 2 OS=Arabidopsis
thaliana GN=SMT2 PE=1 SV=2
Length = 361
Score = 638 bits (1644), Expect = 4e-182
Identities = 298/359 (83%), Positives = 333/359 (92%)
Frame = -1
Query: 1261 MDNVALYCTAALVAGGIYWFICILGPAERKGKRASDLSGGSISAENVKDNYNQYWSFFRK 1082
MD++ L+ T ALVA GIYWF+C+LGPAERKGKRA DLSGGSISAE V+DNY QYWSFFR+
Sbjct: 1 MDSLTLFFTGALVAVGIYWFLCVLGPAERKGKRAVDLSGGSISAEKVQDNYKQYWSFFRR 60
Query: 1081 PKEIESPEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIPGKSDKEATRIHEEMAVDLIK 902
PKEIE+ EKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIPGKS K+ATR+HEEMAVDLI+
Sbjct: 61 PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIPGKSHKDATRLHEEMAVDLIQ 120
Query: 901 VKPGQKILDAGCGVGGPMRAIAAHSKAHVVGITINDYQVKRAKEHNKKAGLDSLCDVVYG 722
VKPGQKILD GCGVGGPMRAIA+HS+A+VVGITIN+YQV RA+ HNKKAGLD+LC+VV G
Sbjct: 121 VKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVNRARLHNKKAGLDALCEVVCG 180
Query: 721 NFLEMPSDENTFDGAYSIEATCHAPKLEEVYAEIFRVMKPGSLYVSYEWVTTDKYNDDDQ 542
NFL+MP D+N+FDGAYSIEATCHAPKLEEVYAEI+RV+KPGS+YVSYEWVTT+K+ +D
Sbjct: 181 NFLQMPFDDNSFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSMYVSYEWVTTEKFKAEDD 240
Query: 541 EHKEVIQGIERGDALPGLRSYSDIATTAKKVGFEIVDERDLAMPPAKPWWSRLKMGRVAY 362
EH EVIQGIERGDALPGLR+Y DIA TAKKVGFEIV E+DLA PPA+PWW+RLKMGR+AY
Sbjct: 241 EHVEVIQGIERGDALPGLRAYVDIAETAKKVGFEIVKEKDLASPPAEPWWTRLKMGRLAY 300
Query: 361 WRNHVVVVVLSAIGVAPKGTVDVHEMLFKTADYLTRGGETGIFSPMHMILCRKPEKSSE 185
WRNH+VV +LSA+GVAPKGTVDVHEMLFKTADYLTRGGETGIFSPMHMILCRKPE E
Sbjct: 301 WRNHIVVQILSAVGVAPKGTVDVHEMLFKTADYLTRGGETGIFSPMHMILCRKPESPEE 359
>sp|O82427|SMT2_ORYSJ 24-methylenesterol C-methyltransferase 2 OS=Oryza sativa
subsp. japonica GN=Smt2-1 PE=2 SV=2
Length = 363
Score = 514 bits (1322), Expect = 8e-145
Identities = 242/362 (66%), Positives = 292/362 (80%), Gaps = 5/362 (1%)
Frame = -1
Query: 1261 MDNVALYCTAALVAGG-IYWFICILGPAERKGKRASDLSGGSISAENVKDNYNQYWSFFR 1085
M+ + TAA V +YWF+ ++G AE KGKRA DL GSI+ + VKD Y QYWSFFR
Sbjct: 1 MEAATMAWTAAGVGMALVYWFVWVMGAAEVKGKRAVDLKMGSITNDKVKDKYTQYWSFFR 60
Query: 1084 KPKEI----ESPEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIPGKSDKEATRIHEEMA 917
+PKE S EKVP FVDTFYNLVTDIYEWGWGQSFHFSPS+PG+S +EATR+HEE
Sbjct: 61 RPKETATTEASAEKVPAFVDTFYNLVTDIYEWGWGQSFHFSPSLPGRSHREATRVHEERV 120
Query: 916 VDLIKVKPGQKILDAGCGVGGPMRAIAAHSKAHVVGITINDYQVKRAKEHNKKAGLDSLC 737
DL++ KPG ++LD GCGVGGPMRAIAAHS ++VVGITIN+YQV RA+ HN+KAGLDS C
Sbjct: 121 ADLLQAKPGHRLLDVGCGVGGPMRAIAAHSGSNVVGITINEYQVNRARAHNRKAGLDSRC 180
Query: 736 DVVYGNFLEMPSDENTFDGAYSIEATCHAPKLEEVYAEIFRVMKPGSLYVSYEWVTTDKY 557
+VV GNFL MP + +FDGAYSIEATCHAP+L++VY E+FRV+KPG LYVSYEWVTT Y
Sbjct: 181 EVVCGNFLSMPFSDASFDGAYSIEATCHAPRLQDVYGEVFRVLKPGGLYVSYEWVTTSLY 240
Query: 556 NDDDQEHKEVIQGIERGDALPGLRSYSDIATTAKKVGFEIVDERDLAMPPAKPWWSRLKM 377
D+ EH E I GIERGDALPGLR +IA+ AK+VGFE++ E DLA+PPA PWW+RLKM
Sbjct: 241 RADNPEHVEAIHGIERGDALPGLRRQDEIASIAKEVGFEVLKELDLALPPALPWWTRLKM 300
Query: 376 GRVAYWRNHVVVVVLSAIGVAPKGTVDVHEMLFKTADYLTRGGETGIFSPMHMILCRKPE 197
GR+AYWRN +VV VL+ + +APKG +VHEML++TA +LTRGGETGIF+PMHM+L RKP
Sbjct: 301 GRIAYWRNSLVVRVLTMLRIAPKGVCEVHEMLYETAQHLTRGGETGIFTPMHMVLLRKPV 360
Query: 196 KS 191
+S
Sbjct: 361 ES 362
>sp|Q6ZIX2|SMT1_ORYSJ Cycloartenol-C-24-methyltransferase 1 OS=Oryza sativa
subsp. japonica GN=Smt1-1 PE=2 SV=1
Length = 344
Score = 228 bits (579), Expect = 1e-058
Identities = 112/262 (42%), Positives = 154/262 (58%), Gaps = 4/262 (1%)
Frame = -1
Query: 1147 GGSISAENVK---DNYNQYWSFFRKPKEIESPEKVPDFVDTFYNLVTDIYEWGWGQSFHF 977
GG I+ + VK D Y +Y ++ KE D V+ +Y+L T YE+GWG+SFHF
Sbjct: 14 GGKITKDEVKSAVDEYEKYHGYY-GGKEEARKSNYTDMVNKYYDLATSFYEYGWGESFHF 72
Query: 976 SPSIPGKSDKEATRIHEEMAVDLIKVKPGQKILDAGCGVGGPMRAIAAHSKAHVVGITIN 797
+ G+S +E+ + HE + VKPG K+LD GCG+GGP+R IA S A V G+ N
Sbjct: 73 AHRWNGESLRESIKRHEHFLALQLGVKPGMKVLDVGCGIGGPLREIAKFSLASVTGLNNN 132
Query: 796 DYQVKRAKEHNKKAGLDSLCDVVYGNFLEMPSDENTFDGAYSIEATCHAPKLEEVYAEIF 617
+YQ+ R KE N+ AG+ CD V +F++MP +NTFD Y+IEATCHAP Y EI+
Sbjct: 133 EYQITRGKELNRVAGVSGTCDFVKADFMKMPFSDNTFDAVYAIEATCHAPDPVGCYKEIY 192
Query: 616 RVMKPGSLYVSYEWVTTDKYNDDDQEHKEVIQGIERGDALPGLRSYSDIATTAKKVGFEI 437
RV+KPG + YEW TD Y ++ HK + IE G+ LP +RS AK GFE+
Sbjct: 193 RVLKPGQCFAVYEWCITDHYEPNNATHKRIKDEIELGNGLPDIRSTQQCLQAAKDAGFEV 252
Query: 436 VDERDLAMPPAKPWWSRLKMGR 371
+ ++DLA PW+ L R
Sbjct: 253 IWDKDLAEDSPVPWYLPLDPSR 274
>sp|Q9LM02|SMT1_ARATH Cycloartenol-C-24-methyltransferase OS=Arabidopsis
thaliana GN=SMT1 PE=2 SV=1
Length = 336
Score = 226 bits (574), Expect = 4e-058
Identities = 111/260 (42%), Positives = 159/260 (61%), Gaps = 5/260 (1%)
Frame = -1
Query: 1162 ASDLSGGSISAENV---KDNYNQYWSFFRKPKEIESPEKVPDFVDTFYNLVTDIYEWGWG 992
AS+L GG I +V + Y QY F E E D V+ +Y+L T YE+GWG
Sbjct: 4 ASNL-GGKIDKSDVLTAVEKYEQY-HVFHGGNEEERKANYTDMVNKYYDLATSFYEYGWG 61
Query: 991 QSFHFSPSIPGKSDKEATRIHEEMAVDLIKVKPGQKILDAGCGVGGPMRAIAAHSKAHVV 812
+SFHF+ G+S +E+ + HE + ++PGQK+LD GCG+GGP+R IA S + V
Sbjct: 62 ESFHFAQRWKGESLRESIKRHEHFLALQLGIQPGQKVLDVGCGIGGPLREIARFSNSVVT 121
Query: 811 GITINDYQVKRAKEHNKKAGLDSLCDVVYGNFLEMPSDENTFDGAYSIEATCHAPKLEEV 632
G+ N+YQ+ R KE N+ AG+D C+ V +F++MP EN+FD Y+IEATCHAP
Sbjct: 122 GLNNNEYQITRGKELNRLAGVDKTCNFVKADFMKMPFPENSFDAVYAIEATCHAPDAYGC 181
Query: 631 YAEIFRVMKPGSLYVSYEWVTTDKYNDDDQEHKEVIQGIERGDALPGLRSYSDIATTAKK 452
Y EI+RV+KPG + +YEW TD ++ D+ EH+++ IE GD LP +R + K+
Sbjct: 182 YKEIYRVLKPGQCFAAYEWCMTDAFDPDNAEHQKIKGEIEIGDGLPDIRLTTKCLEALKQ 241
Query: 451 VGFEIVDERDLAMPPAKPWW 392
GFE++ E+DLA PW+
Sbjct: 242 AGFEVIWEKDLAKDSPVPWY 261
>sp|Q54I98|SMT1_DICDI Probable cycloartenol-C-24-methyltransferase 1
OS=Dictyostelium discoideum GN=smt1 PE=1 SV=1
Length = 354
Score = 216 bits (549), Expect = 4e-055
Identities = 107/255 (41%), Positives = 153/255 (60%), Gaps = 3/255 (1%)
Frame = -1
Query: 1129 ENVKDNYNQYWSFFR--KPKEIES-PEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIPG 959
+ V D N Y F+ K I++ V+TFY+L TD YE+GWGQSFHF+
Sbjct: 30 DKVDDTLNGYKELFKGNDDKAIQARKNNYTHMVNTFYDLATDFYEFGWGQSFHFATRHKY 89
Query: 958 KSDKEATRIHEEMAVDLIKVKPGQKILDAGCGVGGPMRAIAAHSKAHVVGITINDYQVKR 779
+S + + HE + + PG K++D GCGVGGPMR IA S A+VVG+ N+YQ++R
Sbjct: 90 ESFEASIARHEMYMAHQLGLFPGMKVIDIGCGVGGPMRTIARFSGANVVGLNNNEYQIQR 149
Query: 778 AKEHNKKAGLDSLCDVVYGNFLEMPSDENTFDGAYSIEATCHAPKLEEVYAEIFRVMKPG 599
K N+ AGL LC + +F+ +P ++NT+D AY IEATCHAP L +Y E+FR++KPG
Sbjct: 150 GKRLNESAGLSHLCSFIKADFMHVPVEDNTYDCAYQIEATCHAPDLVGLYKEVFRIVKPG 209
Query: 598 SLYVSYEWVTTDKYNDDDQEHKEVIQGIERGDALPGLRSYSDIATTAKKVGFEIVDERDL 419
L+ YEW+ T+K+N +D + + IE G+ LP L ++I AK GFE++ D+
Sbjct: 210 GLFGGYEWIMTNKFNPEDPVEVNIKKQIELGNGLPDLVKPAEIINAAKAAGFEVITAFDV 269
Query: 418 AMPPAKPWWSRLKMG 374
A PW+ L G
Sbjct: 270 AETSELPWYLPLSSG 284
>sp|Q5EN22|ERG6_MAGGR Sterol 24-C-methyltransferase OS=Magnaporthe grisea
GN=ERG6 PE=2 SV=2
Length = 390
Score = 212 bits (539), Expect = 5e-054
Identities = 118/311 (37%), Positives = 169/311 (54%), Gaps = 10/311 (3%)
Frame = -1
Query: 1189 GPAERKGKRASDLSGGSISAENVKDNYNQYWSFFRKPKEIES--PEKVPDFVD---TFYN 1025
G + G +S L +++ D Y ++W E E+ D+ +YN
Sbjct: 31 GSSANMGGLSSMLGKDREASKTAVDQYFRHWDGKTAKTETTKVREERKADYATLTRQYYN 90
Query: 1024 LVTDIYEWGWGQSFHFSPSIPGKSDKEATRIHEEMAVDLIKVKPGQKILDAGCGVGGPMR 845
LVTD YE+GWGQSFHF PG++ A +E I +K G K+LD GCGVGGP R
Sbjct: 91 LVTDFYEYGWGQSFHFCTFAPGETFASAITRYEHTLAHRIGIKKGMKVLDIGCGVGGPAR 150
Query: 844 AIAAHSKAHVVGITINDYQVKRAKEHNKKAGLDS--LCDVVYGNFLEMPSDENTFDGAYS 671
IA + A++ GITIN+YQV+RA+ + + G + V G+F+ +P ++ TFD YS
Sbjct: 151 QIAKFTGANITGITINEYQVERARRYAEMEGYGAGEQLKFVQGDFMALPFEKETFDAVYS 210
Query: 670 IEATCHAPKLEEVYAEIFRVMKPGSLYVSYEWVTTDKYNDDDQEHKEVIQGIERGDALPG 491
IEAT HAPKLE+VY +IF V+KPG ++ YEWV TD Y+++D HKE+ GIE G +
Sbjct: 211 IEATVHAPKLEDVYKQIFNVLKPGGIFGLYEWVMTDAYDENDPHHKEIRFGIEHGGGIAN 270
Query: 490 LRSYSDIATTAKKVGFEIVDERDLA-MPPAKPWWSRLKMGRVAYWRNHVVVVVLSAIGVA 314
L++ K GFE+++ DLA PW+ +G A+ +LS +
Sbjct: 271 LQTAQTAIAAIKAAGFELLESEDLADNSDRAPWY--WPLGGNAWQYASTFGDILSTFTMT 328
Query: 313 PKGTVDVHEML 281
P G H +L
Sbjct: 329 PAGRAIAHTVL 339
>sp|Q96WX4|ERG6_PNECA Sterol 24-C-methyltransferase OS=Pneumocystis carinii
GN=erg6 PE=2 SV=1
Length = 377
Score = 212 bits (539), Expect = 5e-054
Identities = 102/241 (42%), Positives = 153/241 (63%), Gaps = 3/241 (1%)
Frame = -1
Query: 1033 FYNLVTDIYEWGWGQSFHFSPSIPGKSDKEATRIHEEMAVDLIKVKPGQKILDAGCGVGG 854
+YNLVTD YE+GW SFHF +S +A HE ++ G+ +LD GCGVGG
Sbjct: 80 YYNLVTDFYEYGWSTSFHFCRFAKDESFSQAIARHEHYIALHAGIREGETVLDVGCGVGG 139
Query: 853 PMRAIAAHSKAHVVGITINDYQVKRAKEHNKKAGLDSLCDVVYGNFLEMPSDENTFDGAY 674
P I+ + A++VG+ NDYQ++RAK +++K GL + G+F++MP EN+FD Y
Sbjct: 140 PACQISVFTGANIVGLNNNDYQIQRAKYYSEKKGLSDKLKFIKGDFMQMPFPENSFDKIY 199
Query: 673 SIEATCHAPKLEEVYAEIFRVMKPGSLYVSYEWVTTDKYNDDDQEHKEVIQGIERGDALP 494
SIEAT HAP LE VY+EI+RV+KPG LY SYEWV +KY+++D EH++++ GIE GD++P
Sbjct: 200 SIEATIHAPSLEGVYSEIYRVLKPGGLYASYEWVMLNKYDENDPEHQQIVYGIEIGDSIP 259
Query: 493 GLRSYSDIATTAKKVGFEIVDERDLAMPPAK-PWWSRL--KMGRVAYWRNHVVVVVLSAI 323
+ + KVGFEI+ +L+ + PW+ L + +V +R+ + + ++ I
Sbjct: 260 KISKIGEAEAALIKVGFEIIHSEELSTKNSPLPWYYYLDGDLRKVRSFRDFISIARMTTI 319
Query: 322 G 320
G
Sbjct: 320 G 320
>sp|Q6C2D9|ERG6_YARLI Sterol 24-C-methyltransferase OS=Yarrowia lipolytica
GN=ERG6 PE=3 SV=1
Length = 381
Score = 210 bits (534), Expect = 2e-053
Identities = 98/215 (45%), Positives = 141/215 (65%), Gaps = 1/215 (0%)
Frame = -1
Query: 1033 FYNLVTDIYEWGWGQSFHFSPSIPGKSDKEATRIHEEMAVDLIKVKPGQKILDAGCGVGG 854
+YNLVTD YE+GWG SFHFS G++ ++AT HE + ++PG K+LD GCGVGG
Sbjct: 82 YYNLVTDFYEYGWGSSFHFSRYYKGEAFRQATARHEHYLAYKMGIQPGMKVLDVGCGVGG 141
Query: 853 PMRAIAAHSKAHVVGITINDYQVKRAKEHNKKAGLDSLCDVVYGNFLEMPSDENTFDGAY 674
P R IA + A++VG+ NDYQV+R +++ G V G+F++M +N+FD Y
Sbjct: 142 PAREIARFTGANIVGLNNNDYQVERGTHYSEVQGFGDQVTYVKGDFMQMDFPDNSFDAVY 201
Query: 673 SIEATCHAPKLEEVYAEIFRVMKPGSLYVSYEWVTTDKYNDDDQEHKEVIQGIERGDALP 494
+IEAT HAP LE VY+EIFRV+KPG ++ YEWV TD+Y++ + EH+++ GIE+GD +P
Sbjct: 202 AIEATVHAPVLEGVYSEIFRVLKPGGVFGVYEWVMTDEYDESNPEHRDICYGIEKGDGIP 261
Query: 493 GLRSYSDIATTAKKVGFEIVDERDLAMPPAK-PWW 392
+ + VGF+I + DLA A+ PW+
Sbjct: 262 KMYKREVAVKALENVGFDIEYQEDLAADDAEVPWY 296
>sp|Q6CYB3|ERG6_KLULA Sterol 24-C-methyltransferase OS=Kluyveromyces lactis
GN=ERG6 PE=3 SV=1
Length = 371
Score = 209 bits (530), Expect = 6e-053
Identities = 99/219 (45%), Positives = 138/219 (63%), Gaps = 1/219 (0%)
Frame = -1
Query: 1036 TFYNLVTDIYEWGWGQSFHFSPSIPGKSDKEATRIHEEMAVDLIKVKPGQKILDAGCGVG 857
++YN+VTD YE+GWG SFHFS G+S + HE +K ILD GCGVG
Sbjct: 72 SYYNVVTDFYEYGWGSSFHFSRFFKGESFSASVARHEHYLAYKAGIKENDLILDVGCGVG 131
Query: 856 GPMRAIAAHSKAHVVGITINDYQVKRAKEHNKKAGLDSLCDVVYGNFLEMPSDENTFDGA 677
GP R I+ + +++G+ NDYQ+++A + K+ LDS V G+F++M DENTFD
Sbjct: 132 GPARTISRFTGCNIIGLNNNDYQIQKANYYAKRDHLDSKLSFVKGDFMKMEFDENTFDSV 191
Query: 676 YSIEATCHAPKLEEVYAEIFRVMKPGSLYVSYEWVTTDKYNDDDQEHKEVIQGIERGDAL 497
Y+IEATCHAP E VY EI++V+KPG + YEWV TDKY++ + EH+++ IE GD +
Sbjct: 192 YAIEATCHAPTFEGVYGEIYKVLKPGGTFAVYEWVMTDKYDETNPEHRKIAYEIELGDGI 251
Query: 496 PGLRSYSDIATTAKKVGFEIVDERDLAMPPAK-PWWSRL 383
P + S KVGFEI++E DLA + PW++ L
Sbjct: 252 PKMYSVDAARDALSKVGFEILEENDLADNDDEIPWYAPL 290
>sp|Q6BRB7|ERG6_DEBHA Sterol 24-C-methyltransferase OS=Debaryomyces hansenii
GN=ERG6 PE=3 SV=1
Length = 377
Score = 208 bits (528), Expect = 1e-052
Identities = 101/241 (41%), Positives = 145/241 (60%), Gaps = 1/241 (0%)
Frame = -1
Query: 1135 SAENVKDNYNQYW-SFFRKPKEIESPEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIPG 959
++E D Y ++W K E + + +YNLVTD YE+GWG SFHFS G
Sbjct: 42 ASEVANDGYFKHWDGGVTKEDEDKRLSDYSNLTAHYYNLVTDFYEYGWGSSFHFSRYYTG 101
Query: 958 KSDKEATRIHEEMAVDLIKVKPGQKILDAGCGVGGPMRAIAAHSKAHVVGITINDYQVKR 779
++ ++AT HE +++ K+LD GCGVGGP R I + +VG+ NDYQ++R
Sbjct: 102 EAFRQATARHEHFLAHKMQINENMKVLDVGCGVGGPAREICRFTDCSIVGLNNNDYQIER 161
Query: 778 AKEHNKKAGLDSLCDVVYGNFLEMPSDENTFDGAYSIEATCHAPKLEEVYAEIFRVMKPG 599
A + +K LD V G+F++M + +FD Y+IEAT HAP LE VY+EI++V+KPG
Sbjct: 162 ANHYARKYKLDDKLSFVKGDFMQMDFEAESFDAVYAIEATVHAPVLEGVYSEIYKVLKPG 221
Query: 598 SLYVSYEWVTTDKYNDDDQEHKEVIQGIERGDALPGLRSYSDIATTAKKVGFEIVDERDL 419
++ YEWV TDKY+D+++EH+++ GIE GD +P + K VGFEI E DL
Sbjct: 222 GVFGVYEWVMTDKYDDENEEHRKIAYGIEVGDGIPKMYKREVAEKALKSVGFEIEYEADL 281
Query: 418 A 416
A
Sbjct: 282 A 282
>sp|O74198|ERG6_CANAL Sterol 24-C-methyltransferase OS=Candida albicans GN=ERG6
PE=3 SV=1
Length = 376
Score = 206 bits (522), Expect = 5e-052
Identities = 104/268 (38%), Positives = 155/268 (57%), Gaps = 2/268 (0%)
Frame = -1
Query: 1189 GPAERKGKRASDLSGGSISAENVKDNYNQYW-SFFRKPKEIESPEKVPDFVDTFYNLVTD 1013
G + +K ++ ++ +A + Y ++W K E + +YNLVTD
Sbjct: 23 GESYKKTGLSALIAKSKDAASVAAEGYFKHWDGGISKDDEEKRLNDYSQLTHHYYNLVTD 82
Query: 1012 IYEWGWGQSFHFSPSIPGKSDKEATRIHEEMAVDLIKVKPGQKILDAGCGVGGPMRAIAA 833
YE+GWG SFHFS G++ ++AT HE + + K+LD GCGVGGP R I
Sbjct: 83 FYEYGWGSSFHFSRYYKGEAFRQATARHEHFLAHKMNLNENMKVLDVGCGVGGPGREITR 142
Query: 832 HSKAHVVGITINDYQVKRAKEHNKKAGLDSLCDVVYGNFLEMPSDENTFDGAYSIEATCH 653
+ +VG+ NDYQ++RA + KK LD V G+F++M + +FD Y+IEAT H
Sbjct: 143 FTDCEIVGLNNNDYQIERANHYAKKYHLDHKLSYVKGDFMQMDFEPESFDAVYAIEATVH 202
Query: 652 APKLEEVYAEIFRVMKPGSLYVSYEWVTTDKYNDDDQEHKEVIQGIERGDALPGLRSYSD 473
AP LE VY+EI++V+KPG ++ YEWV TDKY++ ++EH+++ GIE GD +P + S
Sbjct: 203 APVLEGVYSEIYKVLKPGGIFGVYEWVMTDKYDETNEEHRKIAYGIEVGDGIPKMYSRKV 262
Query: 472 IATTAKKVGFEIVDERDLA-MPPAKPWW 392
K VGFEI ++DLA + PW+
Sbjct: 263 AEQALKNVGFEIEYQKDLADVDDEIPWY 290
>sp|O14321|ERG6_SCHPO Sterol 24-C-methyltransferase OS=Schizosaccharomyces pombe
GN=SPBC16E9.05 PE=2 SV=1
Length = 378
Score = 206 bits (522), Expect = 5e-052
Identities = 108/273 (39%), Positives = 158/273 (57%), Gaps = 13/273 (4%)
Frame = -1
Query: 1171 GKRASDLSG-GSISAENVKD---NYNQYWSFFRKPKEIESPEK-------VPDFVDTFYN 1025
GK A +G +I++++V + +Y+ F+ + E ES E V+++Y+
Sbjct: 21 GKAAEKKTGLAAIASKDVDEQSRKLQEYFEFWDRNHENESEEDRARRIDGYKSVVNSYYD 80
Query: 1024 LVTDIYEWGWGQSFHFSPSIPGKSDKEATRIHEEMAVDLIKVKPGQKILDAGCGVGGPMR 845
L TD+YE+GW QSFHFS G++ ++ HE + +KPG ++LD GCGVGGP R
Sbjct: 81 LATDLYEYGWSQSFHFSRFYKGEAFAQSIARHEHYLAYRMGIKPGSRVLDVGCGVGGPAR 140
Query: 844 AIAAHSKAHVVGITINDYQVKRAKEHNKKAGLDSLCDVVYGNFLEMPSDENTFDGAYSIE 665
I + ++VG+ NDYQ+ R + K LD V G+F+ MP ++NTFD Y+IE
Sbjct: 141 EITEFTGCNLVGLNNNDYQISRCNNYAVKRNLDKKQVFVKGDFMHMPFEDNTFDYVYAIE 200
Query: 664 ATCHAPKLEEVYAEIFRVMKPGSLYVSYEWVTTDKYNDDDQEHKEVIQGIERGDALPGLR 485
AT HAP LE VY EIFRV+KPG ++ YEWV +D Y+ +H+E+ IE GD +P +
Sbjct: 201 ATVHAPSLEGVYGEIFRVLKPGGVFGVYEWVMSDDYDSSIPKHREIAYNIEVGDGIPQMV 260
Query: 484 SYSDIATTAKKVGFEIVDERDLA--MPPAKPWW 392
D KKVGF +++E DL P PW+
Sbjct: 261 RKCDAVEAIKKVGFNLLEEDDLTDHDNPDLPWY 293
>sp|Q6FRZ7|ERG6_CANGA Sterol 24-C-methyltransferase OS=Candida glabrata GN=ERG6
PE=3 SV=1
Length = 372
Score = 205 bits (521), Expect = 6e-052
Identities = 104/267 (38%), Positives = 156/267 (58%), Gaps = 4/267 (1%)
Frame = -1
Query: 1183 AERKGKRASDLSGGSISAENVKDNYNQYWSFFRKPKEIESP--EKVPDFVDTFYNLVTDI 1010
AE + + LS + Y ++W + KE E E + ++YN+VTD
Sbjct: 22 AESRTGLTALLSKNRNAQREAVSKYLRHWD-GKTDKEAEDRRLEDYNEATHSYYNVVTDF 80
Query: 1009 YEWGWGQSFHFSPSIPGKSDKEATRIHEEMAVDLIKVKPGQKILDAGCGVGGPMRAIAAH 830
YE+GWG SFHFS G++ + A HE+ + +K G +LD GCGVGGP R IA
Sbjct: 81 YEYGWGSSFHFSRFYKGENFQAAMARHEQYLAYMAGIKKGDLVLDVGCGVGGPARTIARF 140
Query: 829 SKAHVVGITINDYQVKRAKEHNKKAGLDSLCDVVYGNFLEMPSDENTFDGAYSIEATCHA 650
+ +++G+ NDYQ+++AK + KK L D V G+F+ M + N+FD Y+IEATCHA
Sbjct: 141 TGCNIIGLNNNDYQIQKAKYYAKKYNLQDHMDFVKGDFMNMEFEPNSFDKVYAIEATCHA 200
Query: 649 PKLEEVYAEIFRVMKPGSLYVSYEWVTTDKYNDDDQEHKEVIQGIERGDALPGLRSYSDI 470
PKLE VY EI++V+KPG + YEWV T+ Y+++++EH+++ IE GD +P + +
Sbjct: 201 PKLEGVYGEIYKVLKPGGTFAVYEWVMTENYDENNEEHRKIAYEIELGDGIPKMFTVDVA 260
Query: 469 ATTAKKVGFEIVDERDLAMPPAK-PWW 392
K VGFE+ +DLA + PW+
Sbjct: 261 KQALKNVGFEVEVSKDLADEDDEIPWY 287
>sp|Q875K1|ERG6_CLAL4 Sterol 24-C-methyltransferase OS=Clavispora lusitaniae
(strain ATCC 42720) GN=ERG6 PE=3 SV=1
Length = 375
Score = 204 bits (517), Expect = 2e-051
Identities = 106/266 (39%), Positives = 158/266 (59%), Gaps = 7/266 (2%)
Frame = -1
Query: 1174 KGKRASDLSGGSISAENVKDN-YNQYWSFFRKPKEIESPEKVPDF---VDTFYNLVTDIY 1007
K + S L + A +V N Y ++W E + +++ D+ +YNLVTD Y
Sbjct: 27 KKRGISALMAKAKEASDVATNGYFKHWD--GGVSEDDEKKRLDDYSSLTKNYYNLVTDFY 84
Query: 1006 EWGWGQSFHFSPSIPGKSDKEATRIHEEMAVDLIKVKPGQKILDAGCGVGGPMRAIAAHS 827
E+GWG SFHFS G++ ++AT HE + + ++LD GCGVGGP R I +
Sbjct: 85 EYGWGSSFHFSRYYKGEAFRQATARHEHFLAHKMNINENMRVLDVGCGVGGPGREICRFT 144
Query: 826 KAHVVGITINDYQVKRAKEHNKKAGLDSLCDVVYGNFLEMPSDENTFDGAYSIEATCHAP 647
+VG+ NDYQV+RA+ + KK LD V G+F++M + +FD Y+IEAT HAP
Sbjct: 145 DCTIVGLNNNDYQVERAQYYAKKYKLDDKLSYVKGDFMQMDFEPESFDAVYAIEATVHAP 204
Query: 646 KLEEVYAEIFRVMKPGSLYVSYEWVTTDKYNDDDQEHKEVIQGIERGDALPGLRSYSDIA 467
LE VY+EI++V+KPG ++ YEWV TDKY+++++EH+++ GIE GD +P +
Sbjct: 205 VLEGVYSEIYKVLKPGGVFGVYEWVMTDKYDENNEEHRKIAYGIEVGDGIPKMYKREVAE 264
Query: 466 TTAKKVGFEIVDERDLA-MPPAKPWW 392
K VGF+I E+DLA + PW+
Sbjct: 265 QALKNVGFDIEYEKDLADVNDEIPWY 290
>sp|P25087|ERG6_YEAST Sterol 24-C-methyltransferase OS=Saccharomyces cerevisiae
GN=ERG6 PE=1 SV=4
Length = 383
Score = 204 bits (517), Expect = 2e-051
Identities = 103/233 (44%), Positives = 145/233 (62%), Gaps = 3/233 (1%)
Frame = -1
Query: 1084 KPKEIESPEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIPGKSDKEATRIHEEMAVDLI 905
K E E + ++YN+VTD YE+GWG SFHFS G+S + HE
Sbjct: 56 KDAEERRLEDYNEATHSYYNVVTDFYEYGWGSSFHFSRFYKGESFAASIARHEHYLAYKA 115
Query: 904 KVKPGQKILDAGCGVGGPMRAIAAHSKAHVVGITINDYQVKRAKEHNKKAGLDSLCDVVY 725
++ G +LD GCGVGGP R IA + +V+G+ NDYQ+ +AK + KK L D V
Sbjct: 116 GIQRGDLVLDVGCGVGGPAREIARFTGCNVIGLNNNDYQIAKAKYYAKKYNLSDQMDFVK 175
Query: 724 GNFLEMPSDENTFDGAYSIEATCHAPKLEEVYAEIFRVMKPGSLYVSYEWVTTDKYNDDD 545
G+F++M +ENTFD Y+IEATCHAPKLE VY+EI++V+KPG + YEWV TDKY++++
Sbjct: 176 GDFMKMDFEENTFDKVYAIEATCHAPKLEGVYSEIYKVLKPGGTFAVYEWVMTDKYDENN 235
Query: 544 QEHKEVIQGIERGDALPGLRSYSDIATTA-KKVGFEIVDERDLAMPPAK-PWW 392
EH+++ IE GD +P + + D+A A K GFE++ DLA + PW+
Sbjct: 236 PEHRKIAYEIELGDGIPKM-FHVDVARKALKNCGFEVLVSEDLADNDDEIPWY 287
>sp|Q9P3R1|ERG6_NEUCR Sterol 24-C-methyltransferase OS=Neurospora crassa
GN=B24P7.240 PE=3 SV=1
Length = 379
Score = 203 bits (516), Expect = 2e-051
Identities = 100/230 (43%), Positives = 141/230 (61%), Gaps = 2/230 (0%)
Frame = -1
Query: 1033 FYNLVTDIYEWGWGQSFHFSPSIPGKSDKEATRIHEEMAVDLIKVKPGQKILDAGCGVGG 854
+YNL TDIYE+GWGQ FHF PG+S +A HE I +K K+LD GCGVGG
Sbjct: 82 YYNLATDIYEYGWGQCFHFCRYSPGESFYQAIARHEHYLAAQIGIKKDMKVLDVGCGVGG 141
Query: 853 PMRAIAAHSKAHVVGITINDYQVKRAKEHNKKAGLDSLCDVVYGNFLEMPSDENTFDGAY 674
P R IA + AH+ G+ NDYQ+ RA + + GL V G+F++M +N+FD Y
Sbjct: 142 PAREIAKFTDAHITGLNNNDYQIDRATHYAVRDGLSGQLKFVKGDFMQMSFPDNSFDAVY 201
Query: 673 SIEATCHAPKLEEVYAEIFRVMKPGSLYVSYEWVTTDKYNDDDQEHKEVIQGIERGDALP 494
+IEAT HAPKLE VY EI+RV+KPG + YEW+ TD Y++D+ EH+++ IE G+ +
Sbjct: 202 AIEATVHAPKLEGVYGEIYRVLKPGGTFGVYEWLMTDNYDNDNVEHRDIRLAIEVGNGIS 261
Query: 493 GLRSYSDIATTAKKVGFEIVDERDLA-MPPAKPWWSRLKMGRVAYWRNHV 347
+ + S+ K VGFE+V DLA PW+ + G + Y ++++
Sbjct: 262 NMVTISEGLAAMKNVGFELVHHEDLADRNDPMPWYWPI-AGELRYMQSYL 310
>sp|Q759S7|ERG6_ASHGO Sterol 24-C-methyltransferase OS=Ashbya gossypii GN=ERG6
PE=3 SV=1
Length = 373
Score = 193 bits (489), Expect = 3e-048
Identities = 98/226 (43%), Positives = 130/226 (57%), Gaps = 2/226 (0%)
Frame = -1
Query: 1036 TFYNLVTDIYEWGWGQSFHFSPSIPGKSDKEATRIHEEMAVDLIKVKPGQKILDAGCGVG 857
++YN+VTD YE+GWG SFHFS G+S + HE + G +LD GCGVG
Sbjct: 73 SYYNVVTDFYEYGWGASFHFSRFYTGESFAMSMARHEHYLAHRAGITSGDLVLDVGCGVG 132
Query: 856 GPMRAIAAHSKAHVVGITINDYQVKRAKEHNKKAGLDSLCDVVYGNFLEMPSDENTFDGA 677
GP R IA + VVG+ NDYQ+ + K +++K GL V G+F+ M + TFD
Sbjct: 133 GPAREIARFTGCRVVGLNNNDYQIMKGKHYSRKLGLGDQVSYVKGDFMNMDFPDATFDKV 192
Query: 676 YSIEATCHAPKLEEVYAEIFRVMKPGSLYVSYEWVTTDKYNDDDQEHKEVIQGIERGDAL 497
Y+IEATCHAP E VY EI+RV+KPG ++ YEWV T+ Y++ + EH+ + IE GD +
Sbjct: 193 YAIEATCHAPSFEGVYGEIYRVLKPGGVFAVYEWVMTENYDETNPEHRRIAYDIELGDGI 252
Query: 496 PGLRSYSDIATTAKKVGFEI-VDERDLAMPPAKPWWSRLKMGRVAY 362
P + S KVGFEI VDE PW+ L G AY
Sbjct: 253 PKMYSVKVARDALAKVGFEILVDEDRADNDDPVPWYYPL-TGEWAY 297
>sp|Q9C6B9|PEAM3_ARATH Putative phosphoethanolamine N-methyltransferase 3
OS=Arabidopsis thaliana GN=NMT3 PE=2 SV=2
Length = 490
Score = 63 bits (151), Expect = 5e-009
Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 2/124 (1%)
Frame = -1
Query: 916 VDLIKVKPGQKILDAGCGVGGPMRAIAAHSKAHVVGITINDYQVKRAKEHNKKAGLDSLC 737
VD++ +KPGQK+LD GCG+GG +A + VVGI ++ + A EH GL
Sbjct: 274 VDMLDLKPGQKVLDVGCGIGGGDFYMAENFDVDVVGIDLSVNMISFALEH--AIGLKCSV 331
Query: 736 DVVYGNFLEMPSDENTFDGAYSIEATCHAPKLEEVYAEIFRVMKPGSLYVSYEWVTTDKY 557
+ + + +NTFD YS + H ++ ++ +KPG + ++ + K
Sbjct: 332 EFEVADCTKKEYPDNTFDVIYSRDTILHIQDKPALFRRFYKWLKPGGKVLITDYCRSPKT 391
Query: 556 NDDD 545
D
Sbjct: 392 PSPD 395
>sp|Q9FR44|PEAM1_ARATH Phosphoethanolamine N-methyltransferase 1 OS=Arabidopsis
thaliana GN=NMT1 PE=2 SV=1
Length = 491
Score = 60 bits (144), Expect = 3e-008
Identities = 42/153 (27%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Frame = -1
Query: 916 VDLIKVKPGQKILDAGCGVGGPMRAIAAHSKAHVVGITINDYQVKRAKEHNKKAGLDSLC 737
V+ + +KPGQK+LD GCG+GG +A HVVGI ++ + A E + GL
Sbjct: 275 VEKMNLKPGQKVLDVGCGIGGGDFYMAEKFDVHVVGIDLSVNMISFALE--RAIGLSCSV 332
Query: 736 DVVYGNFLEMPSDENTFDGAYSIEATCHAPKLEEVYAEIFRVMKPGSLYVSYEWVTTDKY 557
+ + +N+FD YS + H ++ F+ +KPG + ++ + K
Sbjct: 333 EFEVADCTTKHYPDNSFDVIYSRDTILHIQDKPALFRTFFKWLKPGGKVLISDYCRSPK- 391
Query: 556 NDDDQEHKEVIQGIERGDALPGLRSYSDIATTA 458
E E I+ +RG L +++Y + A
Sbjct: 392 -TPSAEFSEYIK--QRGYDLHDVQAYGQMLKDA 421
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,366,676,449
Number of Sequences: 518415
Number of Extensions: 41366676449
Number of Successful Extensions: 294470065
Number of sequences better than 0.0: 0
|
