BLASTX 7.6.2
Query= UN09846 /QuerySize=1399
(1398 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6GLP4|RMD5A_XENLA Protein RMD5 homolog A OS=Xenopus laevis G... 203 3e-051
sp|Q640V2|RMD5A_XENTR Protein RMD5 homolog A OS=Xenopus tropical... 202 6e-051
sp|Q9H871|RMD5A_HUMAN Protein RMD5 homolog A OS=Homo sapiens GN=... 200 3e-050
sp|Q80YQ8|RMD5A_MOUSE Protein RMD5 homolog A OS=Mus musculus GN=... 197 2e-049
sp|Q91YQ7|RMD5B_MOUSE Protein RMD5 homolog B OS=Mus musculus GN=... 195 7e-049
sp|Q96G75|RMD5B_HUMAN Protein RMD5 homolog B OS=Homo sapiens GN=... 194 2e-048
sp|O59668|YB83_SCHPO LisH domain-containing protein C29A3.03c OS... 141 2e-032
sp|Q12508|RMD5_YEAST Sporulation protein RMD5 OS=Saccharomyces c... 102 8e-021
sp|Q2H991|FYV10_CHAGB Protein FYV10 OS=Chaetomium globosum GN=FY... 64 2e-009
sp|Q9URU9|FYV10_SCHPO Protein fyv10 OS=Schizosaccharomyces pombe... 59 6e-008
>sp|Q6GLP4|RMD5A_XENLA Protein RMD5 homolog A OS=Xenopus laevis GN=rmnd5a PE=2
SV=1
Length = 391
Score = 203 bits (515), Expect = 3e-051
Identities = 115/322 (35%), Positives = 190/322 (59%), Gaps = 12/322 (3%)
Frame = +2
Query: 281 QLESAEKELNVALTKYPKVLEKQLNSEISKAYRNNV-EFDT-HVVNQIIANFFYRQGMFE 454
+L S K+++ ++++ K ++K +++IS + + D+ ++++++ F+RQGM +
Sbjct: 74 KLASDHKDIHSSVSRVGKAIDKNFDADISSVGIDGCWQTDSQRILSEVMVEHFFRQGMLD 133
Query: 455 IGDCFVAETGES-ECTTRQSFVEMFMILEAMKGRDLEPALNWAAANSERLKQARSDLEMK 631
+ + E S + + ++ FVE+ ILEA+K R L PAL WA +N E L S LE K
Sbjct: 134 VAEELCQEASLSIDASQKEPFVELNRILEALKVRVLRPALEWAVSNREMLMAQNSSLEFK 193
Query: 632 LHSLQFLKISQG--QNSQEALSYARRHFAVYADSCLSEIQKLVCSLLW-DKNLEQSPYSE 802
LH L F+ + G N QEAL YA ++F +A++ +IQ L+ SL++ + +E SPY
Sbjct: 194 LHRLYFISLLMGGTVNQQEALQYA-KNFQPFAENHQKDIQVLMGSLVYLRQGIENSPYVH 252
Query: 803 FLSPVMWDNAVRELTRQYCNLLGESSESPLSVTVTAGTQALPVLLKYMNVIANKKLD--W 976
L W + TR C+LLG S ESPLSV+ +AG ALP L+ VI ++ W
Sbjct: 253 LLDANQWADICDIFTRDACSLLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCSGVW 312
Query: 977 QTMEQLPVAVELPGEFQFHSVFVCPVSKEQSSEDNPPMMMSCGHVLCKQTITRMSKNGAK 1156
++LP+ V+L + +HS+F CP+ ++Q++E+NPPM + CGH++ + + +M NG+K
Sbjct: 313 NQKDELPIEVDLGKKCWYHSIFACPILRQQTTENNPPMKLVCGHIISRDALNKMF-NGSK 371
Query: 1157 TSFKCPYCPTDVDSTRCKQLHF 1222
KCPYCP + KQ+ F
Sbjct: 372 --LKCPYCPMEQSPGDAKQIFF 391
>sp|Q640V2|RMD5A_XENTR Protein RMD5 homolog A OS=Xenopus tropicalis GN=rmnd5a
PE=2 SV=1
Length = 391
Score = 202 bits (513), Expect = 6e-051
Identities = 114/325 (35%), Positives = 191/325 (58%), Gaps = 18/325 (5%)
Frame = +2
Query: 281 QLESAEKELNVALTKYPKVLEKQLNSEISK-----AYRNNVEFDTHVVNQIIANFFYRQG 445
+L S K+++ ++++ K ++K +++IS ++N+ + ++++++ F+RQG
Sbjct: 74 KLASDHKDIHSSVSRVGKAIDKNFDADISSVGIDGCWQNDSQ---QILSEVMVEHFFRQG 130
Query: 446 MFEIGDCFVAETGES-ECTTRQSFVEMFMILEAMKGRDLEPALNWAAANSERLKQARSDL 622
M ++ + E G S + + ++ FVE+ ILEA+K R L PAL WA +N E L S L
Sbjct: 131 MLDVAEELCQEAGLSIDASQKEPFVELNRILEALKVRVLRPALEWAVSNREMLMAQNSSL 190
Query: 623 EMKLHSLQFLKISQG--QNSQEALSYARRHFAVYADSCLSEIQKLVCSLLW-DKNLEQSP 793
E KLH L F+ + G N +EAL YA ++F +A++ +IQ L+ SL++ + +E SP
Sbjct: 191 EFKLHRLYFISLLMGGTVNQREALQYA-KNFQPFAENHQKDIQVLMGSLVYLRQGIENSP 249
Query: 794 YSEFLSPVMWDNAVRELTRQYCNLLGESSESPLSVTVTAGTQALPVLLKYMNVIANKKLD 973
Y L W + TR C LLG S ESPLSV+ +AG ALP L+ VI ++
Sbjct: 250 YVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCT 309
Query: 974 --WQTMEQLPVAVELPGEFQFHSVFVCPVSKEQSSEDNPPMMMSCGHVLCKQTITRMSKN 1147
W ++LP+ V+L + +HS+F CP+ ++Q++++NPPM + CGH++ + + +M N
Sbjct: 310 GVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMF-N 368
Query: 1148 GAKTSFKCPYCPTDVDSTRCKQLHF 1222
G+K KCPYCP + KQ+ F
Sbjct: 369 GSK--LKCPYCPMEQSPGDAKQIFF 391
>sp|Q9H871|RMD5A_HUMAN Protein RMD5 homolog A OS=Homo sapiens GN=RMND5A PE=1
SV=1
Length = 391
Score = 200 bits (507), Expect = 3e-050
Identities = 116/322 (36%), Positives = 190/322 (59%), Gaps = 12/322 (3%)
Frame = +2
Query: 281 QLESAEKELNVALTKYPKVLEKQLNSEISKAYRNNV-EFDT-HVVNQIIANFFYRQGMFE 454
+L S K+++ ++++ K ++K +S+IS + + D+ ++N+++ F+RQGM +
Sbjct: 74 KLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQADSQRLLNEVMVEHFFRQGMLD 133
Query: 455 IGDCFVAETGES-ECTTRQSFVEMFMILEAMKGRDLEPALNWAAANSERLKQARSDLEMK 631
+ + E+G S + + ++ FVE+ ILEA+K R L PAL WA +N E L S LE K
Sbjct: 134 VAEELCQESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVSNREMLIAQNSSLEFK 193
Query: 632 LHSLQFLKISQG--QNSQEALSYARRHFAVYADSCLSEIQKLVCSLLW-DKNLEQSPYSE 802
LH L F+ + G N +EAL YA ++F +A + +IQ L+ SL++ + +E SPY
Sbjct: 194 LHRLYFISLLMGGTTNQREALQYA-KNFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVH 252
Query: 803 FLSPVMWDNAVRELTRQYCNLLGESSESPLSVTVTAGTQALPVLLKYMNVIANKKLD--W 976
L W + TR C LLG S ESPLSV+ +AG ALP L+ VI ++ W
Sbjct: 253 LLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVW 312
Query: 977 QTMEQLPVAVELPGEFQFHSVFVCPVSKEQSSEDNPPMMMSCGHVLCKQTITRMSKNGAK 1156
++LP+ V+L + +HS+F CP+ ++Q++++NPPM + CGH++ + + +M NG+K
Sbjct: 313 NQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMF-NGSK 371
Query: 1157 TSFKCPYCPTDVDSTRCKQLHF 1222
KCPYCP + KQ+ F
Sbjct: 372 --LKCPYCPMEQSPGDAKQIFF 391
>sp|Q80YQ8|RMD5A_MOUSE Protein RMD5 homolog A OS=Mus musculus GN=Rmnd5a PE=2
SV=1
Length = 391
Score = 197 bits (499), Expect = 2e-049
Identities = 115/322 (35%), Positives = 189/322 (58%), Gaps = 12/322 (3%)
Frame = +2
Query: 281 QLESAEKELNVALTKYPKVLEKQLNSEISKAYRNNV-EFDT-HVVNQIIANFFYRQGMFE 454
+L S K+++ ++++ K ++K +S+IS + + D+ ++N+++ F+RQGM +
Sbjct: 74 KLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQADSQRLLNEVMVEHFFRQGMLD 133
Query: 455 IGDCFVAETGES-ECTTRQSFVEMFMILEAMKGRDLEPALNWAAANSERLKQARSDLEMK 631
+ + E+G S + + ++ FVE+ ILEA+K R L PAL WA +N E L S LE K
Sbjct: 134 VAEELCQESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVSNREMLIAQNSSLEFK 193
Query: 632 LHSLQFLKISQG--QNSQEALSYARRHFAVYADSCLSEIQKLVCSLLW-DKNLEQSPYSE 802
LH L F+ + G N +EAL YA ++F +A + +IQ L+ SL++ + +E SPY
Sbjct: 194 LHRLYFISLLMGGTTNQREALQYA-KNFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVH 252
Query: 803 FLSPVMWDNAVRELTRQYCNLLGESSESPLSVTVTAGTQALPVLLKYMNVIANKKLD--W 976
L W + TR C LLG S ESPLSV+ +AG ALP L+ VI ++ W
Sbjct: 253 LLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVW 312
Query: 977 QTMEQLPVAVELPGEFQFHSVFVCPVSKEQSSEDNPPMMMSCGHVLCKQTITRMSKNGAK 1156
++LP+ V+L + +HS+F CP+ ++Q++++NPPM + CGH++ + + +M NG+K
Sbjct: 313 NQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMF-NGSK 371
Query: 1157 TSFKCPYCPTDVDSTRCKQLHF 1222
KCPYC + KQ+ F
Sbjct: 372 --LKCPYCSMEQSPGDAKQIFF 391
>sp|Q91YQ7|RMD5B_MOUSE Protein RMD5 homolog B OS=Mus musculus GN=Rmnd5b PE=2
SV=1
Length = 393
Score = 195 bits (495), Expect = 7e-049
Identities = 114/324 (35%), Positives = 182/324 (56%), Gaps = 14/324 (4%)
Frame = +2
Query: 281 QLESAEKELNVALTKYPKVLEKQLNSEI----SKAYRNNVEFDTHVVNQIIANFFYRQGM 448
+L S K+++ ++++ K +++ +SEI S A ++ E ++ I Y+QGM
Sbjct: 74 KLASDHKDIHSSVSRVGKAIDRNFDSEICGVVSDAVWDSREKQQQILQMAIVEHLYQQGM 133
Query: 449 FEIGDCFVAE-TGESECTTRQSFVEMFMILEAMKGRDLEPALNWAAANSERLKQARSDLE 625
+ + E T + +Q F+E+ ILEA+ +DL PAL WA ++ +RL + S LE
Sbjct: 134 LSVAEELCQESTLNVDLDFKQPFLELNRILEALHEQDLGPALEWAVSHRQRLLELNSSLE 193
Query: 626 MKLHSLQFLKISQG--QNSQEALSYARRHFAVYADSCLSEIQKLVCSLLWDK-NLEQSPY 796
KLH L F+++ G + EALSYA RHF +A EIQ ++ SL++ + LE+SPY
Sbjct: 194 FKLHRLHFIRLLAGGPEKQLEALSYA-RHFQPFARLHQREIQVMMGSLVYLRLGLEKSPY 252
Query: 797 SEFLSPVMWDNAVRELTRQYCNLLGESSESPLSVTVTAGTQALPVLLKYMNVIANKKLD- 973
L W TR C+LLG S ESPLSV+ +G ALPVL+ VI ++
Sbjct: 253 CHLLDNSHWAEICETFTRDACSLLGLSVESPLSVSFASGCVALPVLMNIKAVIEQRQCTG 312
Query: 974 -WQTMEQLPVAVELPGEFQFHSVFVCPVSKEQSSEDNPPMMMSCGHVLCKQTITRMSKNG 1150
W ++LP+ +EL + +HSVF CP+ ++Q+S+ NPP+ + CGHV+ + + ++ G
Sbjct: 313 VWSHKDELPIEIELGMKCWYHSVFACPILRQQTSDSNPPIKLICGHVISRDALNKLINGG 372
Query: 1151 AKTSFKCPYCPTDVDSTRCKQLHF 1222
KCPYCP + + K++ F
Sbjct: 373 ---KLKCPYCPMEQNPADGKRIIF 393
>sp|Q96G75|RMD5B_HUMAN Protein RMD5 homolog B OS=Homo sapiens GN=RMND5B PE=2
SV=1
Length = 393
Score = 194 bits (491), Expect = 2e-048
Identities = 114/324 (35%), Positives = 182/324 (56%), Gaps = 14/324 (4%)
Frame = +2
Query: 281 QLESAEKELNVALTKYPKVLEKQLNSEI----SKAYRNNVEFDTHVVNQIIANFFYRQGM 448
+L S K+++ ++++ K +++ +SEI S A + E ++ I Y+QGM
Sbjct: 74 KLASDHKDIHSSVSRVGKAIDRNFDSEICGVVSDAVWDAREQQQQILQMAIVEHLYQQGM 133
Query: 449 FEIGDCFVAE-TGESECTTRQSFVEMFMILEAMKGRDLEPALNWAAANSERLKQARSDLE 625
+ + E T + +Q F+E+ ILEA+ +DL PAL WA ++ +RL + S LE
Sbjct: 134 LSVAEELCQESTLNVDLDFKQPFLELNRILEALHEQDLGPALEWAVSHRQRLLELNSSLE 193
Query: 626 MKLHSLQFLKISQGQNSQ--EALSYARRHFAVYADSCLSEIQKLVCSLLWDK-NLEQSPY 796
KLH L F+++ G ++ EALSYA RHF +A EIQ ++ SL++ + LE+SPY
Sbjct: 194 FKLHRLHFIRLLAGGPAKQLEALSYA-RHFQPFARLHQREIQVMMGSLVYLRLGLEKSPY 252
Query: 797 SEFLSPVMWDNAVRELTRQYCNLLGESSESPLSVTVTAGTQALPVLLKYMNVIANKKLD- 973
L W TR C+LLG S ESPLSV+ +G ALPVL+ VI ++
Sbjct: 253 CHLLDSSHWAEICETFTRDACSLLGLSVESPLSVSFASGCVALPVLMNIKAVIEQRQCTG 312
Query: 974 -WQTMEQLPVAVELPGEFQFHSVFVCPVSKEQSSEDNPPMMMSCGHVLCKQTITRMSKNG 1150
W ++LP+ +EL + +HSVF CP+ ++Q+S+ NPP+ + CGHV+ + + ++ G
Sbjct: 313 VWNHKDELPIEIELGMKCWYHSVFACPILRQQTSDSNPPIKLICGHVISRDALNKLINGG 372
Query: 1151 AKTSFKCPYCPTDVDSTRCKQLHF 1222
KCPYCP + + K++ F
Sbjct: 373 ---KLKCPYCPMEQNPADGKRIIF 393
>sp|O59668|YB83_SCHPO LisH domain-containing protein C29A3.03c
OS=Schizosaccharomyces pombe GN=SPBC29A3.03c PE=2 SV=1
Length = 398
Score = 141 bits (354), Expect = 2e-032
Identities = 61/123 (49%), Positives = 87/123 (70%), Gaps = 1/123 (0%)
Frame = +2
Query: 821 WDNAVRELTRQYCNLLGESSESPLSVTVTAGTQALPVLLKYMNVIANKKLDWQTMEQLPV 1000
W + R++C LG S ESPL + V AG ALP+LLK +++ K +W + +LPV
Sbjct: 266 WKSLELLFVREFCAALGMSLESPLDIVVNAGAIALPILLKMSSIMKKKHTEWTSQGELPV 325
Query: 1001 AVELPGEFQFHSVFVCPVSKEQSSEDNPPMMMSCGHVLCKQTITRMSKNGAKTSFKCPYC 1180
+ LP + FHSVF CPVSKEQ++E+NPPMMMSCGHV+ K+++ ++S+NG++ FKCPYC
Sbjct: 326 EIFLPSSYHFHSVFTCPVSKEQATEENPPMMMSCGHVIVKESLRQLSRNGSQ-RFKCPYC 384
Query: 1181 PTD 1189
P +
Sbjct: 385 PNE 387
>sp|Q12508|RMD5_YEAST Sporulation protein RMD5 OS=Saccharomyces cerevisiae
GN=RMD5 PE=1 SV=1
Length = 421
Score = 102 bits (253), Expect = 8e-021
Identities = 57/167 (34%), Positives = 93/167 (55%), Gaps = 9/167 (5%)
Frame = +2
Query: 737 EIQKLVCSLLWDKNLEQSPYSEFLSPVMWDNAVRELT----RQYCNLLGESSESPLSVTV 904
E+ + V LL K+L P + S V + ++E T ++YC +SPL + V
Sbjct: 256 ELMQNVVPLL-TKSLIGQPIEDIDSKV--NKELKECTSLFIKEYCAAKHIFFDSPLFLIV 312
Query: 905 TAGTQALPVLLKYMNVIANKKLDWQTMEQLPVAVELPGEF-QFHSVFVCPVSKEQSSEDN 1081
+G + +KY + +DW T ++LP V+LP FH +F+CPV KE+++ +N
Sbjct: 313 LSGLISFQFFIKYKTIRELAHVDWTTKDELPFDVKLPDFLTHFHPIFICPVLKEETTTEN 372
Query: 1082 PPMMMSCGHVLCKQTITRMSKNGAKTSFKCPYCPTDVDSTRCKQLHF 1222
PP ++C H++ K+ + R+SKNG T FKCPYCP + + K++ F
Sbjct: 373 PPYSLACHHIISKKALDRLSKNGTIT-FKCPYCPVNTSMSSTKKVRF 418
>sp|Q2H991|FYV10_CHAGB Protein FYV10 OS=Chaetomium globosum GN=FYV10 PE=3 SV=1
Length = 441
Score = 64 bits (155), Expect = 2e-009
Identities = 38/176 (21%), Positives = 79/176 (44%), Gaps = 3/176 (1%)
Frame = +2
Query: 407 VNQIIANFFYRQGMFEIGDCFVAETGESECTTRQSFVEMFMILEAMKGRDLEPALNWAAA 586
+++++ ++ R G E G + +FV M I ++++G ++ ALNW
Sbjct: 129 LDRLLVDYMLRHGYDSSAIALADERGMRDLVDIDTFVVMSRIRKSLEGGSVQEALNWCNE 188
Query: 587 NSERLKQARSDLEMKLHSLQFLKISQGQN---SQEALSYARRHFAVYADSCLSEIQKLVC 757
N + L++ +S+LE L Q++++ + + EA+ +AR++ + ++ EI +
Sbjct: 189 NKKELRKMQSNLEFLLRCQQYIEMMRTDSPAKMAEAIHHARKYITPFTETYPVEISSIAG 248
Query: 758 SLLWDKNLEQSPYSEFLSPVMWDNAVRELTRQYCNLLGESSESPLSVTVTAGTQAL 925
L + PY+ S W + LLG L + +++G AL
Sbjct: 249 LLAYRPGTISEPYASLYSASRWQKLADTFVEAHLKLLGLPMTPLLHIALSSGLSAL 304
>sp|Q9URU9|FYV10_SCHPO Protein fyv10 OS=Schizosaccharomyces pombe GN=fyv10 PE=2
SV=1
Length = 404
Score = 59 bits (142), Expect = 6e-008
Identities = 41/200 (20%), Positives = 91/200 (45%), Gaps = 2/200 (1%)
Frame = +2
Query: 407 VNQIIANFFYRQGMFEIGDCFVAETGESECTTRQSFVEMFMILEAMKGRDLEPALNWAAA 586
+N+++A++ G ++ + +I +++ ++L+ L+W +
Sbjct: 120 LNRLVADYMMANGYHGAAALLCKDSQLENLVDLGIYKRYQLIHDSILQQELKEVLSWCSE 179
Query: 587 NSERLKQARSDLEMKLHSLQFLKISQGQNSQEALSYARRHFAVYADSCLSEIQKLVCSLL 766
+ LK+ S LE+++ +F+++ + + +A+++A+ HF +A+ + +Q L
Sbjct: 180 HRAILKKNNSTLELEVRLQRFIELIKSKKLCQAIAFAKAHFGTWANEHPARLQLAAALLA 239
Query: 767 WDKNLEQSPYSEFLSPVMWDNAVRELTRQYCNLLGESSESPLSVTVTAGTQALPVLLKYM 946
+ + SPYS LS W+ T + + S L + AG +L L Y+
Sbjct: 240 FPEFTNGSPYSLLLSDDRWEYLASLFTSNFTAVHNIPSVPLLHALLAAGLSSLKTPLCYL 299
Query: 947 NVIANK--KLDWQTMEQLPV 1000
+ + L QT++Q PV
Sbjct: 300 DANDDNPLALQSQTVKQCPV 319
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,366,676,449
Number of Sequences: 518415
Number of Extensions: 41366676449
Number of Successful Extensions: 294470065
Number of sequences better than 0.0: 0
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