BLASTX 7.6.2
Query= UN09848 /QuerySize=744
(743 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q86KK2|FHIT_DICDI Bis(5'-adenosyl)-triphosphatase OS=Dictyost... 155 3e-037
sp|Q1KZG4|FHIT_BOVIN Bis(5'-adenosyl)-triphosphatase OS=Bos taur... 154 7e-037
sp|P49789|FHIT_HUMAN Bis(5'-adenosyl)-triphosphatase OS=Homo sap... 149 3e-035
sp|Q9JIX3|FHIT_RAT Bis(5'-adenosyl)-triphosphatase OS=Rattus nor... 148 6e-035
sp|O89106|FHIT_MOUSE Bis(5'-adenosyl)-triphosphatase OS=Mus musc... 147 1e-034
sp|O76463|NFT1_CAEEL Nitrilase and fragile histidine triad fusio... 137 1e-031
sp|P49776|APH1_SCHPO Bis(5'-nucleosyl)-tetraphosphatase [asymmet... 124 6e-028
sp|O76464|NFT1_DROME Nitrilase and fragile histidine triad fusio... 107 1e-022
sp|B3LFZ1|HNT2_YEAS1 Bis(5'-adenosyl)-triphosphatase OS=Saccharo... 97 1e-019
sp|C7GQV5|HNT2_YEAS2 Bis(5'-adenosyl)-triphosphatase OS=Saccharo... 97 1e-019
sp|B5VGI4|HNT2_YEAS6 Bis(5'-adenosyl)-triphosphatase OS=Saccharo... 97 1e-019
sp|A6ZYQ3|HNT2_YEAS7 Bis(5'-adenosyl)-triphosphatase OS=Saccharo... 97 1e-019
sp|C8Z5L6|HNT2_YEAS8 Bis(5'-adenosyl)-triphosphatase OS=Saccharo... 97 1e-019
sp|P49775|HNT2_YEAST Bis(5'-adenosyl)-triphosphatase OS=Saccharo... 97 1e-019
sp|Q11066|YHI2_MYCTU Uncharacterized HIT-like protein Rv1262c/MT... 60 1e-008
>sp|Q86KK2|FHIT_DICDI Bis(5'-adenosyl)-triphosphatase OS=Dictyostelium
discoideum GN=fhit PE=3 SV=1
Length = 149
Score = 155 bits (391), Expect = 3e-037
Identities = 71/129 (55%), Positives = 98/129 (75%), Gaps = 1/129 (0%)
Frame = +1
Query: 94 FGPYKIDPREVFYATPLSYAMVNLRPLLPGHVLVCPRRLVPRFTDLTADETSDLWLTAQK 273
FGP+ I E+F+ T LS+A+VNL+P+LPGHVLVCP+R+VPR DLT +E +DLWL+AQ+
Sbjct: 6 FGPWLIRQSEIFFTTELSFALVNLKPVLPGHVLVCPKRIVPRVKDLTKEEFTDLWLSAQR 65
Query: 274 VGSRIETFHNASSLTLAIQDGPQAGQSVPHVHIHVLPRKGGDFEKNDEIYDAIDEKEKEL 453
+ S +E N +T AIQDG AGQ+V HVHIH++PRK DFE ND+IY+ I EKE+E
Sbjct: 66 ISSVVEEHFNGDGITFAIQDGKNAGQTVEHVHIHIIPRKKFDFENNDQIYNEI-EKEREP 124
Query: 454 KQKLDLDKD 480
+ +++K+
Sbjct: 125 RSYEEMEKE 133
>sp|Q1KZG4|FHIT_BOVIN Bis(5'-adenosyl)-triphosphatase OS=Bos taurus GN=FHIT PE=2
SV=1
Length = 149
Score = 154 bits (388), Expect = 7e-037
Identities = 75/146 (51%), Positives = 104/146 (71%), Gaps = 5/146 (3%)
Frame = +1
Query: 85 SFVFGPYKIDPREVFYATPLSYAMVNLRPLLPGHVLVCPRRLVPRFTDLTADETSDLWLT 264
SF FG + I P VF T LS+A+VN +P++PGHVLVCP R V RF D++ +E +DL+
Sbjct: 2 SFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFRDMSPEEVADLFQA 61
Query: 265 AQKVGSRIETFHNASSLTLAIQDGPQAGQSVPHVHIHVLPRKGGDFEKNDEIYDAIDEKE 444
AQ+VG+ +E +SLT ++QDGP+AGQ+V HVH+H+LPRK GDF +ND IYDA+++ +
Sbjct: 62 AQRVGTVVEKHFQGTSLTFSMQDGPEAGQTVKHVHVHILPRKAGDFHRNDSIYDALEKHD 121
Query: 445 KELKQKLDLDKDRVDRSIEEMANEAS 522
+E D D + RS EEMA EA+
Sbjct: 122 RE-----DKDSPALWRSEEEMAAEAA 142
>sp|P49789|FHIT_HUMAN Bis(5'-adenosyl)-triphosphatase OS=Homo sapiens GN=FHIT
PE=1 SV=3
Length = 147
Score = 149 bits (374), Expect = 3e-035
Identities = 76/146 (52%), Positives = 100/146 (68%), Gaps = 7/146 (4%)
Frame = +1
Query: 85 SFVFGPYKIDPREVFYATPLSYAMVNLRPLLPGHVLVCPRRLVPRFTDLTADETSDLWLT 264
SF FG + I P VF T LS+A+VN +P++PGHVLVCP R V RF DL DE +DL+ T
Sbjct: 2 SFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQT 61
Query: 265 AQKVGSRIETFHNASSLTLAIQDGPQAGQSVPHVHIHVLPRKGGDFEKNDEIYDAIDEKE 444
Q+VG+ +E + +SLT ++QDGP+AGQ+V HVH+HVLPRK GDF +ND IY+ + + +
Sbjct: 62 TQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKHD 121
Query: 445 KELKQKLDLDKDRVDRSIEEMANEAS 522
KE D RS EEMA EA+
Sbjct: 122 KE-------DFPASWRSEEEMAAEAA 140
>sp|Q9JIX3|FHIT_RAT Bis(5'-adenosyl)-triphosphatase OS=Rattus norvegicus GN=Fhit
PE=1 SV=1
Length = 150
Score = 148 bits (371), Expect = 6e-035
Identities = 73/149 (48%), Positives = 99/149 (66%), Gaps = 5/149 (3%)
Frame = +1
Query: 85 SFVFGPYKIDPREVFYATPLSYAMVNLRPLLPGHVLVCPRRLVPRFTDLTADETSDLWLT 264
SF FG + I P VF T LS+A+VN +P++PGHVL+CP R V RF DL DE +DL+
Sbjct: 2 SFKFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLMCPLRPVERFRDLRPDEVADLFQV 61
Query: 265 AQKVGSRIETFHNASSLTLAIQDGPQAGQSVPHVHIHVLPRKGGDFEKNDEIYDAIDEKE 444
Q+VG+ +E +S+T ++QDGP+AGQ+V HVH+H+LPRK GDF +ND IYD + + +
Sbjct: 62 TQRVGTVVEKHFQGTSITFSMQDGPEAGQTVKHVHVHILPRKSGDFRRNDNIYDELQKHD 121
Query: 445 KELKQKLDLDKDRVDRSIEEMANEASQYR 531
+E + D RS EEMA EA R
Sbjct: 122 RE-----EEDSPAFWRSEEEMAAEAEVLR 145
>sp|O89106|FHIT_MOUSE Bis(5'-adenosyl)-triphosphatase OS=Mus musculus GN=Fhit
PE=2 SV=3
Length = 150
Score = 147 bits (369), Expect = 1e-034
Identities = 74/149 (49%), Positives = 99/149 (66%), Gaps = 5/149 (3%)
Frame = +1
Query: 85 SFVFGPYKIDPREVFYATPLSYAMVNLRPLLPGHVLVCPRRLVPRFTDLTADETSDLWLT 264
SF FG + I P VF T LS+A+VN +P++PGHVLVCP R V RF DL DE +DL+
Sbjct: 2 SFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFRDLHPDEVADLFQV 61
Query: 265 AQKVGSRIETFHNASSLTLAIQDGPQAGQSVPHVHIHVLPRKGGDFEKNDEIYDAIDEKE 444
Q+VG+ +E +S+T ++QDGP+AGQ+V HVH+HVLPRK GDF +ND IYD + + +
Sbjct: 62 TQRVGTVVEKHFQGTSITFSMQDGPEAGQTVKHVHVHVLPRKAGDFPRNDNIYDELQKHD 121
Query: 445 KELKQKLDLDKDRVDRSIEEMANEASQYR 531
+E + D RS +EMA EA R
Sbjct: 122 RE-----EEDSPAFWRSEKEMAAEAEALR 145
>sp|O76463|NFT1_CAEEL Nitrilase and fragile histidine triad fusion protein
NitFhit OS=Caenorhabditis elegans GN=nft-1 PE=1 SV=1
Length = 440
Score = 137 bits (343), Expect = 1e-031
Identities = 65/140 (46%), Positives = 93/140 (66%), Gaps = 1/140 (0%)
Frame = +1
Query: 43 LSSVRCRRQMSTSSSFVFGPYKIDPREVFYATPLSYAMVNLRPLLPGHVLVCPRRLVPRF 222
L ++ + S + F + I +FY+TP S+ VNL+P+ GHVLV P+R+VPR
Sbjct: 284 LYTLHINEKSSETGGLKFARFNIPADHIFYSTPHSFVFVNLKPVTDGHVLVSPKRVVPRL 343
Query: 223 TDLTADETSDLWLTAQKVGSRIETFHNASSLTLAIQDGPQAGQSVPHVHIHVLPRKGGDF 402
TDLT ET+DL++ A+KV + +E HN +S T+ +QDG AGQ+VPHVHIH+LPR+ GDF
Sbjct: 344 TDLTDAETADLFIVAKKVQAMLEKHHNVTSTTICVQDGKDAGQTVPHVHIHILPRRAGDF 403
Query: 403 EKNDEIYDAIDEKEKELKQK 462
N EIY + +KE ++K
Sbjct: 404 GDN-EIYQKLASHDKEPERK 422
>sp|P49776|APH1_SCHPO Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
OS=Schizosaccharomyces pombe GN=aph1 PE=1 SV=2
Length = 182
Score = 124 bits (311), Expect = 6e-028
Identities = 58/111 (52%), Positives = 78/111 (70%)
Frame = +1
Query: 121 EVFYATPLSYAMVNLRPLLPGHVLVCPRRLVPRFTDLTADETSDLWLTAQKVGSRIETFH 300
+VFY T LS A VNL+P+LPGHVLV P+R VPR DLT E +DL+ + +KV IE
Sbjct: 15 QVFYRTKLSAAFVNLKPILPGHVLVIPQRAVPRLKDLTPSELTDLFTSVRKVQQVIEKVF 74
Query: 301 NASSLTLAIQDGPQAGQSVPHVHIHVLPRKGGDFEKNDEIYDAIDEKEKEL 453
+AS+ + IQDG AGQ+VPHVH+H++PRK DF +ND +Y +++ E L
Sbjct: 75 SASASNIGIQDGVDAGQTVPHVHVHIIPRKKADFSENDLVYSELEKNEGNL 125
>sp|O76464|NFT1_DROME Nitrilase and fragile histidine triad fusion protein
NitFhit OS=Drosophila melanogaster GN=NitFhit PE=1 SV=1
Length = 460
Score = 107 bits (266), Expect = 1e-022
Identities = 49/114 (42%), Positives = 73/114 (64%)
Frame = +1
Query: 109 IDPREVFYATPLSYAMVNLRPLLPGHVLVCPRRLVPRFTDLTADETSDLWLTAQKVGSRI 288
+D R +FY + +A NLR ++ GHVLV +R+ PR L E +D++ T V +
Sbjct: 323 VDKRTIFYESEHCFAFTNLRCVVKGHVLVSTKRVTPRLCGLDCAEMADMFTTVCLVQRLL 382
Query: 289 ETFHNASSLTLAIQDGPQAGQSVPHVHIHVLPRKGGDFEKNDEIYDAIDEKEKE 450
E + +S T+ +QDG QAGQ+VPHVH H++PR+ GDF ND+IY +DE+ +E
Sbjct: 383 EKIYQTTSATVTVQDGAQAGQTVPHVHFHIMPRRLGDFGHNDQIYVKLDERAEE 436
>sp|B3LFZ1|HNT2_YEAS1 Bis(5'-adenosyl)-triphosphatase OS=Saccharomyces
cerevisiae (strain RM11-1a) GN=HNT2 PE=3 SV=2
Length = 206
Score = 97 bits (239), Expect = 1e-019
Identities = 49/106 (46%), Positives = 71/106 (66%), Gaps = 2/106 (1%)
Frame = +1
Query: 121 EVFYATPLSYAMVNLRPLLPGHVLVCP-RRLVPRFTDLTADETSDLWLTAQKVGSRIETF 297
+VFY + +YA+VNL+P++PGHVL+ P R V +DLT E+ D + T Q + I+
Sbjct: 15 QVFYKSKYTYALVNLKPIVPGHVLIVPLRTTVLNLSDLTMPESQDYFKTLQLIHRFIKWQ 74
Query: 298 HNASSLTLAIQDGPQAGQSVPHVHIHVLPRKGGDFEKNDEIYDAID 435
+ A S+ +AIQDGP+AGQSVPH+H H++PR + D IYD +D
Sbjct: 75 YKADSINVAIQDGPEAGQSVPHLHTHIIPRYKIN-NVGDLIYDKLD 119
>sp|C7GQV5|HNT2_YEAS2 Bis(5'-adenosyl)-triphosphatase OS=Saccharomyces
cerevisiae (strain JAY291) GN=HNT2 PE=3 SV=2
Length = 206
Score = 97 bits (239), Expect = 1e-019
Identities = 49/106 (46%), Positives = 71/106 (66%), Gaps = 2/106 (1%)
Frame = +1
Query: 121 EVFYATPLSYAMVNLRPLLPGHVLVCP-RRLVPRFTDLTADETSDLWLTAQKVGSRIETF 297
+VFY + +YA+VNL+P++PGHVL+ P R V +DLT E+ D + T Q + I+
Sbjct: 15 QVFYKSKYTYALVNLKPIVPGHVLIVPLRTTVLNLSDLTMPESQDYFKTLQLIHRFIKWQ 74
Query: 298 HNASSLTLAIQDGPQAGQSVPHVHIHVLPRKGGDFEKNDEIYDAID 435
+ A S+ +AIQDGP+AGQSVPH+H H++PR + D IYD +D
Sbjct: 75 YKADSINVAIQDGPEAGQSVPHLHTHIIPRYKIN-NVGDLIYDKLD 119
>sp|B5VGI4|HNT2_YEAS6 Bis(5'-adenosyl)-triphosphatase OS=Saccharomyces
cerevisiae (strain AWRI1631) GN=HNT2 PE=3 SV=2
Length = 206
Score = 97 bits (239), Expect = 1e-019
Identities = 49/106 (46%), Positives = 71/106 (66%), Gaps = 2/106 (1%)
Frame = +1
Query: 121 EVFYATPLSYAMVNLRPLLPGHVLVCP-RRLVPRFTDLTADETSDLWLTAQKVGSRIETF 297
+VFY + +YA+VNL+P++PGHVL+ P R V +DLT E+ D + T Q + I+
Sbjct: 15 QVFYKSKYTYALVNLKPIVPGHVLIVPLRTTVLNLSDLTMPESQDYFKTLQLIHRFIKWQ 74
Query: 298 HNASSLTLAIQDGPQAGQSVPHVHIHVLPRKGGDFEKNDEIYDAID 435
+ A S+ +AIQDGP+AGQSVPH+H H++PR + D IYD +D
Sbjct: 75 YKADSINVAIQDGPEAGQSVPHLHTHIIPRYKIN-NVGDLIYDKLD 119
>sp|A6ZYQ3|HNT2_YEAS7 Bis(5'-adenosyl)-triphosphatase OS=Saccharomyces
cerevisiae (strain YJM789) GN=HNT2 PE=3 SV=2
Length = 206
Score = 97 bits (239), Expect = 1e-019
Identities = 49/106 (46%), Positives = 71/106 (66%), Gaps = 2/106 (1%)
Frame = +1
Query: 121 EVFYATPLSYAMVNLRPLLPGHVLVCP-RRLVPRFTDLTADETSDLWLTAQKVGSRIETF 297
+VFY + +YA+VNL+P++PGHVL+ P R V +DLT E+ D + T Q + I+
Sbjct: 15 QVFYKSKYTYALVNLKPIVPGHVLIVPLRTTVLNLSDLTMPESQDYFKTLQLIHRFIKWQ 74
Query: 298 HNASSLTLAIQDGPQAGQSVPHVHIHVLPRKGGDFEKNDEIYDAID 435
+ A S+ +AIQDGP+AGQSVPH+H H++PR + D IYD +D
Sbjct: 75 YKADSINVAIQDGPEAGQSVPHLHTHIIPRYKIN-NVGDLIYDKLD 119
>sp|C8Z5L6|HNT2_YEAS8 Bis(5'-adenosyl)-triphosphatase OS=Saccharomyces
cerevisiae (strain Lalvin EC1118 / Prise de mousse) GN=HNT2 PE=3 SV=2
Length = 206
Score = 97 bits (239), Expect = 1e-019
Identities = 49/106 (46%), Positives = 71/106 (66%), Gaps = 2/106 (1%)
Frame = +1
Query: 121 EVFYATPLSYAMVNLRPLLPGHVLVCP-RRLVPRFTDLTADETSDLWLTAQKVGSRIETF 297
+VFY + +YA+VNL+P++PGHVL+ P R V +DLT E+ D + T Q + I+
Sbjct: 15 QVFYKSKYTYALVNLKPIVPGHVLIVPLRTTVLNLSDLTMPESQDYFKTLQLIHRFIKWQ 74
Query: 298 HNASSLTLAIQDGPQAGQSVPHVHIHVLPRKGGDFEKNDEIYDAID 435
+ A S+ +AIQDGP+AGQSVPH+H H++PR + D IYD +D
Sbjct: 75 YKADSINVAIQDGPEAGQSVPHLHTHIIPRYKIN-NVGDLIYDKLD 119
>sp|P49775|HNT2_YEAST Bis(5'-adenosyl)-triphosphatase OS=Saccharomyces
cerevisiae GN=HNT2 PE=1 SV=2
Length = 206
Score = 97 bits (239), Expect = 1e-019
Identities = 49/106 (46%), Positives = 71/106 (66%), Gaps = 2/106 (1%)
Frame = +1
Query: 121 EVFYATPLSYAMVNLRPLLPGHVLVCP-RRLVPRFTDLTADETSDLWLTAQKVGSRIETF 297
+VFY + +YA+VNL+P++PGHVL+ P R V +DLT E+ D + T Q + I+
Sbjct: 15 QVFYKSKYTYALVNLKPIVPGHVLIVPLRTTVLNLSDLTMPESQDYFKTLQLIHRFIKWQ 74
Query: 298 HNASSLTLAIQDGPQAGQSVPHVHIHVLPRKGGDFEKNDEIYDAID 435
+ A S+ +AIQDGP+AGQSVPH+H H++PR + D IYD +D
Sbjct: 75 YKADSINVAIQDGPEAGQSVPHLHTHIIPRYKIN-NVGDLIYDKLD 119
>sp|Q11066|YHI2_MYCTU Uncharacterized HIT-like protein Rv1262c/MT1300
OS=Mycobacterium tuberculosis GN=Rv1262c PE=4 SV=2
Length = 144
Score = 60 bits (144), Expect = 1e-008
Identities = 30/83 (36%), Positives = 45/83 (54%)
Frame = +1
Query: 151 AMVNLRPLLPGHVLVCPRRLVPRFTDLTADETSDLWLTAQKVGSRIETFHNASSLTLAIQ 330
A++++RP GH LV P+R TD + +D+ Q++ A + +AI
Sbjct: 26 AILDIRPFTRGHTLVLPKRHTVDLTDTPPEALADMVAIGQRIARAARATKLADATHIAIN 85
Query: 331 DGPQAGQSVPHVHIHVLPRKGGD 399
DG A Q+V HVH+HVLP + GD
Sbjct: 86 DGRAAFQTVFHVHLHVLPPRNGD 108
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,366,676,449
Number of Sequences: 518415
Number of Extensions: 41366676449
Number of Successful Extensions: 294470065
Number of sequences better than 0.0: 0
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