BLASTX 7.6.2
Query= UN09868 /QuerySize=1527
(1526 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8QZR1|ATTY_MOUSE Tyrosine aminotransferase OS=Mus musculus G... 229 6e-059
sp|P04694|ATTY_RAT Tyrosine aminotransferase OS=Rattus norvegicu... 226 4e-058
sp|Q58CZ9|ATTY_BOVIN Tyrosine aminotransferase OS=Bos taurus GN=... 222 6e-057
sp|P17735|ATTY_HUMAN Tyrosine aminotransferase OS=Homo sapiens G... 221 1e-056
sp|Q54K95|ATTY_DICDI Tyrosine aminotransferase OS=Dictyostelium ... 196 3e-049
sp|P33447|ATTY_TRYCR Tyrosine aminotransferase OS=Trypanosoma cr... 172 7e-042
sp|P53001|AAT1_BACSU Aspartate aminotransferase OS=Bacillus subt... 129 5e-029
sp|P23034|AAT_BACY2 Aspartate aminotransferase OS=Bacillus sp. (... 116 6e-025
sp|Q59228|AAT_BACST Aspartate aminotransferase OS=Bacillus stear... 114 2e-024
sp|P63499|AAT_MYCBO Probable aspartate aminotransferase OS=Mycob... 97 3e-019
sp|P63498|AAT_MYCTU Probable aspartate aminotransferase OS=Mycob... 97 3e-019
sp|Q60317|AAT1_METJA Probable aspartate aminotransferase 1 OS=Me... 96 6e-019
sp|Q9V0L2|AAT_PYRAB Aspartate aminotransferase OS=Pyrococcus aby... 89 8e-017
sp|P14909|AAT_SULSO Aspartate aminotransferase OS=Sulfolobus sol... 87 3e-016
sp|Q56232|AAT_THET8 Aspartate aminotransferase OS=Thermus thermo... 83 4e-015
sp|P71348|Y286_HAEIN Uncharacterized aminotransferase HI_0286 OS... 80 5e-014
sp|A0LEA5|DAPAT_SYNFM LL-diaminopimelate aminotransferase OS=Syn... 76 7e-013
sp|Q972A2|AAT_SULTO Aspartate aminotransferase OS=Sulfolobus tok... 74 3e-012
sp|Q0P5G4|KAT3_BOVIN Kynurenine--oxoglutarate transaminase 3 OS=... 67 2e-010
sp|Q6YP21|KAT3_HUMAN Kynurenine--oxoglutarate transaminase 3 OS=... 67 2e-010
>sp|Q8QZR1|ATTY_MOUSE Tyrosine aminotransferase OS=Mus musculus GN=Tat PE=2
SV=1
Length = 454
Score = 229 bits (582), Expect = 6e-059
Identities = 121/350 (34%), Positives = 199/350 (56%), Gaps = 3/350 (0%)
Frame = -1
Query: 1313 KAVVKAVICGNGNAYASSIGLPVAKDAVAEYLNRDLDNKLTGDDVFMTVGCKQAIELVVD 1134
+A+ A+ G N YA SIG +++ VA Y + + L DV +T GC QAIEL +
Sbjct: 95 QAMKDALDSGKYNGYAPSIGYLSSREEVASYYHCP-EAPLEAKDVILTSGCSQAIELCLA 153
Query: 1133 ILAKPEANILIPRPGFPADYVRSLFKKLEVRRYEVIPEKEFEIDLDSVKEMADKNTFAIF 954
+LA P NILIPRPGF + +EV+ Y ++PEK +EIDL ++ + D+ T +
Sbjct: 154 VLANPGQNILIPRPGFSLYRTLAESMGIEVKLYNLLPEKSWEIDLKQLESLIDEKTACLV 213
Query: 953 IINPHNPNGNYYTEPHLEQLAKLARELGVMVVSDEVYRWTVFGSNPFVPMGKFSSIVPVI 774
+ NP NP G+ +++ HL+++ +A V +++DE+Y VF + PM S+ VP++
Sbjct: 214 VNNPSNPCGSVFSKRHLQKILAVAERQCVPILADEIYGDMVFSDCKYEPMATLSTNVPIL 273
Query: 773 THGSISKGWSVPGWRTGWLAMHDLNGVFKSTKVLKAANEFLEINSKPPTVIQAAIPTILE 594
+ G ++K W VPGWR GW+ +HD +F ++ + + P T++Q A+ +IL+
Sbjct: 274 SCGGLAKRWLVPGWRLGWILIHDRRDIF-GNEIRDGLVKLSQRILGPCTIVQGALKSILQ 332
Query: 593 KTPQEFFDRRQSFLKDKVDIAYAKLKEIPTLTCYMKPEACTFLWTELDPSHFVDIEDDQD 414
+TPQEF+ SFLK D+ Y L IP L ++P +L ++ HF + E+D +
Sbjct: 333 RTPQEFYQDTLSFLKSNADLCYGALSAIPGLQ-PVRPSGAMYLMVGIEMEHFPEFENDVE 391
Query: 413 FCNKLAKEENLVVLPGIAFGQKNWLRHSIDMETSILEDAFTRLKCFCERH 264
F +L E+++ LP F N+ R I + ++ +A +R++ FCE+H
Sbjct: 392 FTERLIAEQSVHCLPATCFEYPNFFRVVITVPEVMMLEACSRIQEFCEQH 441
>sp|P04694|ATTY_RAT Tyrosine aminotransferase OS=Rattus norvegicus GN=Tat PE=1
SV=1
Length = 454
Score = 226 bits (575), Expect = 4e-058
Identities = 120/350 (34%), Positives = 198/350 (56%), Gaps = 3/350 (0%)
Frame = -1
Query: 1313 KAVVKAVICGNGNAYASSIGLPVAKDAVAEYLNRDLDNKLTGDDVFMTVGCKQAIELVVD 1134
+A+ A+ G N YA SIG +++ VA Y + + L DV +T GC QAIEL +
Sbjct: 95 QAMKDALDSGKYNGYAPSIGYLSSREEVASYYHCH-EAPLEAKDVILTSGCSQAIELCLA 153
Query: 1133 ILAKPEANILIPRPGFPADYVRSLFKKLEVRRYEVIPEKEFEIDLDSVKEMADKNTFAIF 954
+LA P NILIPRPGF + +EV+ Y ++PEK +EIDL ++ + D+ T +
Sbjct: 154 VLANPGQNILIPRPGFSLYRTLAESMGIEVKLYNLLPEKSWEIDLKQLESLIDEKTACLV 213
Query: 953 IINPHNPNGNYYTEPHLEQLAKLARELGVMVVSDEVYRWTVFGSNPFVPMGKFSSIVPVI 774
+ NP NP G+ +++ HL+++ +A V +++DE+Y VF + P+ S+ VP++
Sbjct: 214 VNNPSNPCGSVFSKRHLQKILAVAERQCVPILADEIYGDMVFSDCKYEPLANLSTNVPIL 273
Query: 773 THGSISKGWSVPGWRTGWLAMHDLNGVFKSTKVLKAANEFLEINSKPPTVIQAAIPTILE 594
+ G ++K W VPGWR GW+ +HD +F ++ + + P T++Q A+ +IL+
Sbjct: 274 SCGGLAKRWLVPGWRLGWILIHDRRDIF-GNEIRDGLVKLSQRILGPCTIVQGALKSILQ 332
Query: 593 KTPQEFFDRRQSFLKDKVDIAYAKLKEIPTLTCYMKPEACTFLWTELDPSHFVDIEDDQD 414
+TPQEF+ SFLK D+ Y L IP L ++P +L ++ HF + E+D +
Sbjct: 333 RTPQEFYHDTLSFLKSNADLCYGALAAIPGLQ-PVRPSGAMYLMVGIEMEHFPEFENDVE 391
Query: 413 FCNKLAKEENLVVLPGIAFGQKNWLRHSIDMETSILEDAFTRLKCFCERH 264
F +L E+ + LP F N+ R I + ++ +A +R++ FCE+H
Sbjct: 392 FTERLIAEQAVHCLPATCFEYPNFFRVVITVPEVMMLEACSRIQEFCEQH 441
>sp|Q58CZ9|ATTY_BOVIN Tyrosine aminotransferase OS=Bos taurus GN=TAT PE=2 SV=1
Length = 447
Score = 222 bits (565), Expect = 6e-057
Identities = 118/350 (33%), Positives = 195/350 (55%), Gaps = 3/350 (0%)
Frame = -1
Query: 1313 KAVVKAVICGNGNAYASSIGLPVAKDAVAEYLNRDLDNKLTGDDVFMTVGCKQAIELVVD 1134
+A+ A+ G N Y SIG +++ VA Y + + L DV +T GC QAIEL +
Sbjct: 88 QAMKDALDSGKFNGYVPSIGYLSSREEVASYYHCP-EAPLEAKDVILTSGCSQAIELCLA 146
Query: 1133 ILAKPEANILIPRPGFPADYVRSLFKKLEVRRYEVIPEKEFEIDLDSVKEMADKNTFAIF 954
+LA P NIL+PRPGF + +EV+ Y ++PEK +EIDL ++ + D+ T +
Sbjct: 147 VLANPGQNILVPRPGFSLYRTLAESMGIEVKLYNLLPEKNWEIDLKQLESLIDEKTVCLI 206
Query: 953 IINPHNPNGNYYTEPHLEQLAKLARELGVMVVSDEVYRWTVFGSNPFVPMGKFSSIVPVI 774
+ NP NP G+ ++ HL+++ +A V +++DE+Y VF + F P+ SS VP++
Sbjct: 207 VNNPSNPCGSVFSRRHLQKILAVAARQCVPILADEIYGDMVFSDSKFEPLATLSSKVPIL 266
Query: 773 THGSISKGWSVPGWRTGWLAMHDLNGVFKSTKVLKAANEFLEINSKPPTVIQAAIPTILE 594
+ G ++K W VPGWR GW+ +HD +F ++ + + P T++Q A+ +IL
Sbjct: 267 SCGGLAKRWLVPGWRMGWILIHDRRDIF-GNEIRDGLTKLSQRILGPCTLVQGALKSILC 325
Query: 593 KTPQEFFDRRQSFLKDKVDIAYAKLKEIPTLTCYMKPEACTFLWTELDPSHFVDIEDDQD 414
+TP+ F+ SFLK D+ Y L IP L + P +L ++ HF + E+D +
Sbjct: 326 RTPRVFYHNTLSFLKSNADLCYGALAAIPGLR-PIHPSGAMYLMVGIEMEHFPEFENDVE 384
Query: 413 FCNKLAKEENLVVLPGIAFGQKNWLRHSIDMETSILEDAFTRLKCFCERH 264
F +L E+++ LP F N+ R I + ++ +A +R++ FCE+H
Sbjct: 385 FTEQLVAEQSVHCLPATCFEYPNFFRVVITVPEVMMLEACSRIQEFCEQH 434
>sp|P17735|ATTY_HUMAN Tyrosine aminotransferase OS=Homo sapiens GN=TAT PE=1
SV=1
Length = 454
Score = 221 bits (563), Expect = 1e-056
Identities = 116/350 (33%), Positives = 198/350 (56%), Gaps = 3/350 (0%)
Frame = -1
Query: 1313 KAVVKAVICGNGNAYASSIGLPVAKDAVAEYLNRDLDNKLTGDDVFMTVGCKQAIELVVD 1134
+A+ A+ G N YA SIG +++ +A Y + + L DV +T GC QAI+L +
Sbjct: 95 QAMKDALDSGKYNGYAPSIGFLSSREEIASYYHCP-EAPLEAKDVILTSGCSQAIDLCLA 153
Query: 1133 ILAKPEANILIPRPGFPADYVRSLFKKLEVRRYEVIPEKEFEIDLDSVKEMADKNTFAIF 954
+LA P NIL+PRPGF + +EV+ Y ++PEK +EIDL ++ + D+ T +
Sbjct: 154 VLANPGQNILVPRPGFSLYKTLAESMGIEVKLYNLLPEKSWEIDLKQLEYLIDEKTACLI 213
Query: 953 IINPHNPNGNYYTEPHLEQLAKLARELGVMVVSDEVYRWTVFGSNPFVPMGKFSSIVPVI 774
+ NP NP G+ +++ HL+++ +A V +++DE+Y VF + P+ S+ VP++
Sbjct: 214 VNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVFSDCKYEPLATLSTDVPIL 273
Query: 773 THGSISKGWSVPGWRTGWLAMHDLNGVFKSTKVLKAANEFLEINSKPPTVIQAAIPTILE 594
+ G ++K W VPGWR GW+ +HD +F ++ + + P T++Q A+ +IL
Sbjct: 274 SCGGLAKRWLVPGWRLGWILIHDRRDIF-GNEIRDGLVKLSQRILGPCTIVQGALKSILC 332
Query: 593 KTPQEFFDRRQSFLKDKVDIAYAKLKEIPTLTCYMKPEACTFLWTELDPSHFVDIEDDQD 414
+TP EF+ SFLK D+ Y L IP L ++P +L ++ HF + E+D +
Sbjct: 333 RTPGEFYHNTLSFLKSNADLCYGALAAIPGLR-PVRPSGAMYLMVGIEMEHFPEFENDVE 391
Query: 413 FCNKLAKEENLVVLPGIAFGQKNWLRHSIDMETSILEDAFTRLKCFCERH 264
F +L E+++ LP F N++R I + ++ +A +R++ FCE+H
Sbjct: 392 FTERLVAEQSVHCLPATCFEYPNFIRVVITVPEVMMLEACSRIQEFCEQH 441
>sp|Q54K95|ATTY_DICDI Tyrosine aminotransferase OS=Dictyostelium discoideum
GN=tat PE=3 SV=1
Length = 417
Score = 196 bits (498), Expect = 3e-049
Identities = 108/356 (30%), Positives = 192/356 (53%), Gaps = 7/356 (1%)
Frame = -1
Query: 1319 AEKAVVKAVICGNGNAYASSIGLPVAKDAVAEYLNRDLDNKLTGDDVFMTVGCKQAIELV 1140
A +++ + N Y S G +A++AVA+Y+ +KLT D+ + G AIEL
Sbjct: 62 ANDLLIENIKSSKFNGYPPSTGYEIAREAVAKYVETP-TSKLTSKDIIVASGASGAIELA 120
Query: 1139 VDILAKPEANILIPRPGFPADYVRSLFKKLEVRRYEVIPEKEFEIDLDSVKEMADKNTFA 960
+ +L NIL+P+PGFP S K + V+ Y ++ ++ F +DL+ ++ + D T A
Sbjct: 121 IGVLLNEGDNILVPKPGFPLYECTSKTKFINVKHYNLLEKQGFNVDLEHLRSLIDDKTKA 180
Query: 959 IFIINPHNPNGNYYTEPHLEQLAKLARELGVMVVSDEVYRWTVFGSNPFVPMGKFSSIVP 780
I + NP NP G Y++ HL + ++ARE + +++DE+Y FG + F PM + VP
Sbjct: 181 ILVNNPSNPCGIVYSKQHLLDIIQVAREYCLPIIADEIYSDLTFGEHKFYPMASLTDKVP 240
Query: 779 VITHGSISKGWSVPGWRTGWLAMHDLNGVFKSTKVLKAANEFLEINSKPPTVIQAAIPTI 600
+++ G I+K + VPGWR GW+A+HD + +F + ++++ ++ P +++Q+ +P +
Sbjct: 241 ILSIGGIAKRFLVPGWRLGWVAIHDRDNIFSNGRIIEGLISLSQVILGPNSLVQSILPKL 300
Query: 599 LEKTPQEFFDRRQSFLKDKVDIAYAKLK-EIPTLTCYMKP---EACTFLWTELDPSHFVD 432
L+ PQ + K +++KL ++ + +KP + E+D S + D
Sbjct: 301 LD--PQNTQVKEWCSTITKTLESHSKLTVDMLSKANGLKPVCSSGTMYQMIEIDCSKYED 358
Query: 431 IEDDQDFCNKLAKEENLVVLPGIAFGQKNWLRHSIDMETSILEDAFTRLKCFCERH 264
I DD +F KL +E+++ +L G F N+ R L +A+ R+ FCE H
Sbjct: 359 IADDNEFVGKLLEEQSVFLLQGTVFSLPNFFRIVFCAPIDKLTEAYERIIEFCETH 414
>sp|P33447|ATTY_TRYCR Tyrosine aminotransferase OS=Trypanosoma cruzi PE=1 SV=2
Length = 416
Score = 172 bits (435), Expect = 7e-042
Identities = 113/387 (29%), Positives = 183/387 (47%), Gaps = 19/387 (4%)
Frame = -1
Query: 1376 PQGKPIL------PPRNSSPESSHTAEKAVVKAVICGNGNAYASSIGLPVAKDAVAEYL- 1218
P KPI+ P + + +S K + +A+ N Y ++G P A++AVA +
Sbjct: 30 PSPKPIIKLSVGDPTLDKNLLTSAAQIKKLKEAIDSQECNGYFPTVGSPEAREAVATWWR 89
Query: 1217 -----NRDLDNKLTGDDVFMTVGCKQAIELVVDILAKPEANILIPRPGFPADYVRSLFKK 1053
+L + + D+V + G I + + + L+P+PGFP
Sbjct: 90 NSFVHKEELKSTIVKDNVVLCSGGSHGILMAITAICDAGDYALVPQPGFPHYETVCKAYG 149
Query: 1052 LEVRRYEVIPEKEFEIDLDSVKEMADKNTFAIFIINPHNPNGNYYTEPHLEQLAKLAREL 873
+ + Y PE ++E DLD ++ + D T + + NP NP G+ ++ H+E + +LA EL
Sbjct: 150 IGMHFYNCRPENDWEADLDEIRRLKDDKTKLLIVTNPSNPCGSNFSRKHVEDIVRLAEEL 209
Query: 872 GVMVVSDEVYRWTVF-GSNP---FVPMGKFSSIVPVITHGSISKGWSVPGWRTGWLAMHD 705
+ + SDE+Y VF G +P F + F + VP + G +K VPGWR GWL D
Sbjct: 210 RLPLFSDEIYAGMVFKGKDPNATFTSVADFETTVPRVILGGTAKNLVVPGWRLGWLLYVD 269
Query: 704 LNGVFKSTKVLKAANEFLEINSKPPTVIQAAIPTILEKTPQEFFDRRQSFLKDKVDIAYA 525
+G L+ + P TV+QAA+ L TPQE D+ + +++ Y
Sbjct: 270 PHG--NGPSFLEGLKRVGMLVCGPCTVVQAALGEALLNTPQEHLDQIVAKIEESAMYLYN 327
Query: 524 KLKEIPTLTCYMKPEACTFLWTELDPSHFVDIEDDQDFCNKLAKEENLVVLPGIAFGQKN 345
+ E L M P +L + +D + DI+ D +F KL +EEN+ VLPG F
Sbjct: 328 HIGECIGLAPTM-PRGAMYLMSRIDLEKYRDIKTDVEFFEKLLEEENVQVLPGTIFHAPG 386
Query: 344 WLRHSIDMETSILEDAFTRLKCFCERH 264
+ R + + +A R+K FC+RH
Sbjct: 387 FTRLTTTRPVEVYREAVERIKAFCQRH 413
>sp|P53001|AAT1_BACSU Aspartate aminotransferase OS=Bacillus subtilis GN=aspB
PE=3 SV=1
Length = 393
Score = 129 bits (324), Expect = 5e-029
Identities = 93/337 (27%), Positives = 155/337 (45%), Gaps = 20/337 (5%)
Frame = -1
Query: 1271 YASSIGLPVAKDAVAEYLNRDLDNKLTGDDVFMTVGCKQAIELVVDILAKPEANILIPRP 1092
Y S GL K+++AE RD + + + + G K A+ + ++ E ++IP P
Sbjct: 63 YTPSGGLAELKNSIAEKFKRDQNIEYKPSQIIVCTGAKHALYTLFQVILDEEDEVIIPTP 122
Query: 1091 ---GFPADYVRSLFKKLEVRRYEVIPEKEFEIDLDSVKEMADKNTFAIFIINPHNPNGNY 921
+P + K + V E + E F+I + +K + T AI I +P NP G
Sbjct: 123 YWVSYPEQVKLAGGKPVYV---EGLEENHFKISPEQLKNAITEKTKAIVINSPSNPTGVM 179
Query: 920 YTEPHLEQLAKLARELGVMVVSDEVYRWTVFGSNPFVPMGKFSSIV---PVITHGSISKG 750
YTE L L ++ E +++VSDE+Y +G V + + S + VI +G +SK
Sbjct: 180 YTEEELSALGEVCLEHDILIVSDEIYEKLTYGGKKHVSIAQLSDRLKEQTVIING-VSKS 238
Query: 749 WSVPGWRTGWLAMHDLNGVFKSTKVLKAANEFLEINSKPPTVIQAAIPTILEKTPQEFFD 570
S+ GWR G+ A S ++KA ++ PT I P E +
Sbjct: 239 HSMTGWRIGYAA--------GSEDIIKAMTNLASHSTSNPTSIAQYGAIAAYNGPSEPLE 290
Query: 569 RRQSFLKDKVDIAYAKLKEIPTLTCYMKPEACTFLWTEL-DPSHFVDIEDDQDFCNKLAK 393
+ + +++ YAKL EIP +C +KPE +L+ + + +D +F L +
Sbjct: 291 EMREAFEHRLNTIYAKLIEIPGFSC-VKPEGAFYLFPNAKEAAQSCGFKDVDEFVKALLE 349
Query: 392 EENLVVLPGIAFGQKNWLRHSIDMETSILEDAFTRLK 282
EE + ++PG FG +R S +LE+A R+K
Sbjct: 350 EEKVAIVPGSGFGSPENVRLSYATSLDLLEEAIERIK 386
>sp|P23034|AAT_BACY2 Aspartate aminotransferase OS=Bacillus sp. (strain YM-2)
PE=1 SV=1
Length = 392
Score = 116 bits (289), Expect = 6e-025
Identities = 81/332 (24%), Positives = 145/332 (43%), Gaps = 14/332 (4%)
Frame = -1
Query: 1271 YASSIGLPVAKDAVAEYLNRDLDNKLTGDDVFMTVGCKQAIELVVDILAKPEANILIPRP 1092
Y S GLP K A+ E RD + +++ + VG K + + ++ ++IP P
Sbjct: 65 YTPSGGLPALKQAIIEKFKRDNQLEYKPNEIIVGVGAKHVLYTLFQVILNEGDEVIIPIP 124
Query: 1091 GFPADYVRSLFKKLEVRRY-EVIPEKEFEIDLDSVKEMADKNTFAIFIINPHNPNGNYYT 915
+ Y + V Y E E+ ++I + +K T A+ I +P NP G YT
Sbjct: 125 -YWVSYPEQVKLAGGVPVYIEATSEQNYKITAEQLKNAITDKTKAVIINSPSNPTGMVYT 183
Query: 914 EPHLEQLAKLARELGVMVVSDEVYRWTVFGSNPFVPMGKFSSIV--PVITHGSISKGWSV 741
LE +AK+A E +++VSDE+Y ++ + + S V I +SK S+
Sbjct: 184 REELEDIAKIALENNILIVSDEIYEKLLYNGAEHFSIAQISEEVKAQTIVINGVSKSHSM 243
Query: 740 PGWRTGWLAMHDLNGVFKSTKVLKAANEFLEINSKPPTVIQAAIPTILEKTPQEFFDRRQ 561
GWR G+ A + ++ A + ++ PT PQ+ + +
Sbjct: 244 TGWRIGYAA--------GNADIINAMTDLASHSTSNPTTASQYAAIEAYNGPQDSVEEMR 295
Query: 560 SFLKDKVDIAYAKLKEIPTLTCYMKPEACTFLWTEL-DPSHFVDIEDDQDFCNKLAKEEN 384
+ +++ Y KL IP +KP+ +L ++ + + +F + L E N
Sbjct: 296 KAFESRLETIYPKLSAIPGFK-VVKPQGAFYLLPDVSEAAQKTGFASVDEFASALLTEAN 354
Query: 383 LVVLPGIAFGQKNWLRHSIDMETSILEDAFTR 288
+ V+PG FG + +R S +++E+A R
Sbjct: 355 VAVIPGSGFGAPSTIRISYATSLNLIEEAIER 386
>sp|Q59228|AAT_BACST Aspartate aminotransferase OS=Bacillus stearothermophilus
GN=aspC PE=3 SV=1
Length = 393
Score = 114 bits (285), Expect = 2e-024
Identities = 92/347 (26%), Positives = 155/347 (44%), Gaps = 17/347 (4%)
Frame = -1
Query: 1310 AVVKAVICGNGNAYASSIGLPVAKDAVAEYLNRDLDNKLTGDDVFMTVGCKQAIELVVDI 1131
A +KA+ G+ Y S GLP K+ + + RD +V + VG K A+ + +
Sbjct: 51 AAIKAMNEGH-TKYTPSGGLPALKEEIIKKFARDQGLDYEPAEVIVCVGAKHALYTLFQV 109
Query: 1130 LAKPEANILIPRPGFPADYVRSLFKKLEVRRY-EVIPEKEFEIDLDSVKEMADKNTFAIF 954
L ++IP P + Y + V Y E + + F+I + +K+ T A+
Sbjct: 110 LLDEGDEVIIPTP-YWVSYPEQVKLAGGVPVYVEGLEQNHFKITPEQLKQAITPRTKAVI 168
Query: 953 IINPHNPNGNYYTEPHLEQLAKLARELGVMVVSDEVYRWTVFGSNPFVPMGKFS---SIV 783
I +P NP G YT L+ L ++ GV++VSDE+Y +G V + + S
Sbjct: 169 INSPSNPTGMIYTAEELKALGEVCLAHGVLIVSDEIYEKLTYGGAKHVSIAELSPELKAQ 228
Query: 782 PVITHGSISKGWSVPGWRTGWLAMHDLNGVFKSTKVLKAANEFLEINSKPPTVIQAAIPT 603
VI +G +SK S+ GWR G+ A ++KA + ++ PT I
Sbjct: 229 TVIING-VSKSHSMTGWRIGYAA--------GPKDIIKAMTDLASHSTSNPTSIAQYAAI 279
Query: 602 ILEKTPQEFFDRRQSFLKDKVDIAYAKLKEIPTLTCYMKPEACTFLWTEL-DPSHFVDIE 426
PQE ++ + + +++I Y KL +IP TC +KP+ +L+ + +
Sbjct: 280 AAYSGPQEPVEQMRQAFEQRLNIIYDKLVQIPGFTC-VKPQGAFYLFPNAREAAAMAGCR 338
Query: 425 DDQDFCNKLAKEENLVVLPGIAFGQKNWLRHSIDMETSILEDAFTRL 285
+F L +E + ++PG FG + +R S LE A R+
Sbjct: 339 TVDEFVAALLEEAKVALVPGSGFGAPDNVRLSYATSLDALETAVERI 385
>sp|P63499|AAT_MYCBO Probable aspartate aminotransferase OS=Mycobacterium bovis
GN=aspC PE=3 SV=1
Length = 429
Score = 97 bits (240), Expect = 3e-019
Identities = 72/283 (25%), Positives = 128/283 (45%), Gaps = 8/283 (2%)
Frame = -1
Query: 1187 DDVFMTVGCKQAIELVVDILAKPEANILIPRPGFPADYVRSLFKKLEVRRYEVIPEKEFE 1008
DDV++ G + I + + L +LIP P +P + Y + ++
Sbjct: 121 DDVYLGNGVSELITMTLQALLDNGDQVLIPSPDYPLWTASTSLAGGTPVHYLCDETQGWQ 180
Query: 1007 IDLDSVKEMADKNTFAIFIINPHNPNGNYYTEPHLEQLAKLARELGVMVVSDEVYRWTVF 828
D+ ++ + T A+ +INP+NP G Y+ L Q+ LAR+ +++++DE+Y ++
Sbjct: 181 PDIADLESKITERTKALVVINPNNPTGAVYSCEILTQMVDLARKHQLLLLADEIYDKILY 240
Query: 827 GSNPFVPMGKFSSIVPVITHGSISKGWSVPGWRTGWLAMHDLNGVFKSTKVLKAANEFLE 648
+ + + + +T +SK + V G+R GWLA+ ++ ++
Sbjct: 241 DDAKHISLASIAPDMLCLTFNGLSKAYRVAGYRAGWLAI--TGPKEHASSFIEGIGLLAN 298
Query: 647 INSKPPTVIQAAIPTILEKTPQ-EFFDRRQSFLKDKVDIAYAKLKEIPTLTCYMKPEACT 471
+ P Q AI L E L ++ DIA+ KL EIP ++C +KP
Sbjct: 299 MRLCPNVPAQHAIQVALGGHQSIEDLVLPGGRLLEQRDIAWTKLNEIPGVSC-VKPAGAL 357
Query: 470 FLWTELDPSHFVDIEDDQDFCNKLAKEENLVVLPGIAFGQKNW 342
+ + LDP + DI+DD+ L E ++V G F NW
Sbjct: 358 YAFPRLDPEVY-DIDDDEQLVLDLLLSEKILVTQGTGF---NW 396
>sp|P63498|AAT_MYCTU Probable aspartate aminotransferase OS=Mycobacterium
tuberculosis GN=aspC PE=3 SV=1
Length = 429
Score = 97 bits (240), Expect = 3e-019
Identities = 72/283 (25%), Positives = 128/283 (45%), Gaps = 8/283 (2%)
Frame = -1
Query: 1187 DDVFMTVGCKQAIELVVDILAKPEANILIPRPGFPADYVRSLFKKLEVRRYEVIPEKEFE 1008
DDV++ G + I + + L +LIP P +P + Y + ++
Sbjct: 121 DDVYLGNGVSELITMTLQALLDNGDQVLIPSPDYPLWTASTSLAGGTPVHYLCDETQGWQ 180
Query: 1007 IDLDSVKEMADKNTFAIFIINPHNPNGNYYTEPHLEQLAKLARELGVMVVSDEVYRWTVF 828
D+ ++ + T A+ +INP+NP G Y+ L Q+ LAR+ +++++DE+Y ++
Sbjct: 181 PDIADLESKITERTKALVVINPNNPTGAVYSCEILTQMVDLARKHQLLLLADEIYDKILY 240
Query: 827 GSNPFVPMGKFSSIVPVITHGSISKGWSVPGWRTGWLAMHDLNGVFKSTKVLKAANEFLE 648
+ + + + +T +SK + V G+R GWLA+ ++ ++
Sbjct: 241 DDAKHISLASIAPDMLCLTFNGLSKAYRVAGYRAGWLAI--TGPKEHASSFIEGIGLLAN 298
Query: 647 INSKPPTVIQAAIPTILEKTPQ-EFFDRRQSFLKDKVDIAYAKLKEIPTLTCYMKPEACT 471
+ P Q AI L E L ++ DIA+ KL EIP ++C +KP
Sbjct: 299 MRLCPNVPAQHAIQVALGGHQSIEDLVLPGGRLLEQRDIAWTKLNEIPGVSC-VKPAGAL 357
Query: 470 FLWTELDPSHFVDIEDDQDFCNKLAKEENLVVLPGIAFGQKNW 342
+ + LDP + DI+DD+ L E ++V G F NW
Sbjct: 358 YAFPRLDPEVY-DIDDDEQLVLDLLLSEKILVTQGTGF---NW 396
>sp|Q60317|AAT1_METJA Probable aspartate aminotransferase 1
OS=Methanocaldococcus jannaschii GN=MJ0001 PE=3 SV=1
Length = 375
Score = 96 bits (237), Expect = 6e-019
Identities = 54/189 (28%), Positives = 103/189 (54%), Gaps = 5/189 (2%)
Frame = -1
Query: 1271 YASSIGLPVAKDAVAEYLNRDLDNKLTGDDVFMTVGCKQAIELVVDILAKPEANILIPRP 1092
Y+ + G+P ++ ++ L D + + D++ +T G +A+ L + L +LIP P
Sbjct: 56 YSPNNGIPELREEISNKLKDDYNLDVDKDNIIVTCGASEALMLSIMTLIDRGDEVLIPNP 115
Query: 1091 GFPADYVRSLFKKLEVRRYEVIPEKEFEIDLDSVKEMADKNTFAIFIINPHNPNGNYYTE 912
F + + + F + +++ ++ ++ F IDL+ VKE K T I +P NP G Y +
Sbjct: 116 SFVSYFSLTEFAEGKIKNIDL--DENFNIDLEKVKESITKKTKLIIFNSPSNPTGKVYDK 173
Query: 911 PHLEQLAKLARELGVMVVSDEVYRWTVFGSNPFVPMGKFSSIVPVITHGSISKGWSVPGW 732
++ LA++A + +++VSDEVY ++ + PM +F+ +I SK +++ GW
Sbjct: 174 ETIKGLAEIAEDYNLIIVSDEVYDKIIYDKKHYSPM-QFTDRCILI--NGFSKTYAMTGW 230
Query: 731 RTGWLAMHD 705
R G+LA+ D
Sbjct: 231 RIGYLAVSD 239
>sp|Q9V0L2|AAT_PYRAB Aspartate aminotransferase OS=Pyrococcus abyssi GN=aspC
PE=3 SV=1
Length = 389
Score = 89 bits (219), Expect = 8e-017
Identities = 59/194 (30%), Positives = 98/194 (50%), Gaps = 14/194 (7%)
Frame = -1
Query: 1271 YASSIGLPVAKDAVAEYLNRDLDNKLTGD---DVFMTVGCKQAIELVVDILAKPEANILI 1101
Y +IGLP ++A+AE L + N + D ++ + VG QA + + K +LI
Sbjct: 59 YGPNIGLPELREAIAEKLKK--QNNIEADPNKEIMVLVGANQAFLMGLSAFLKDGEEVLI 116
Query: 1100 PRPGFPADYVRSLF----KKLEVRRYEVIPEKEFEIDLDSVKEMADKNTFAIFIINPHNP 933
P P F Y ++ K +EV YE E EF +++D +K+ + T A+ I +P NP
Sbjct: 117 PTPAF-VSYAPAVILAGGKPVEVPTYE---ENEFRLNVDELKKYVTEKTKALIINSPCNP 172
Query: 932 NGNYYTEPHLEQLAKLARELGVMVVSDEVYRWTVFGSNPFVPMGKFSSIVP-VITHGSIS 756
G+ + LE++A A E ++V+SDEVY ++ + + IT S
Sbjct: 173 TGSVLKKKDLEEIADFAVEHDLIVISDEVYEHFIYDDVKHYSIASLDGMFERTITVNGFS 232
Query: 755 KGWSVPGWRTGWLA 714
K +++ GWR G++A
Sbjct: 233 KTFAMTGWRLGFVA 246
>sp|P14909|AAT_SULSO Aspartate aminotransferase OS=Sulfolobus solfataricus
GN=aspC PE=1 SV=2
Length = 402
Score = 87 bits (214), Expect = 3e-016
Identities = 54/194 (27%), Positives = 97/194 (50%), Gaps = 16/194 (8%)
Frame = -1
Query: 1271 YASSIGLPVAKDAVAEYLNRDLDNKLTGDDVFMTVGCKQAIELVVDILAKPEANILIPRP 1092
Y S+ G+ ++ +A+YLN + ++V +T G K A+ LV + P +++P P
Sbjct: 68 YTSAFGIDELREKIAQYLNTRYGTDVKKEEVIVTPGAKPALFLVFILYINPSDEVILPDP 127
Query: 1091 GF--PADYVRSLFKKLEVRRYEVIPEKEFEIDLDSVKEMADKNTFAIFIINPHNPNGNYY 918
F A+ V+ L K + E+ F ID+D ++ K T I NPHNP G +
Sbjct: 128 SFYSYAEVVKLLGGKPIYANLKWSREEGFSIDVDDLQSKISKRTKMIVFNNPHNPTGTLF 187
Query: 917 TEPHLEQLAKLARELGVMVVSDEVYRWTVFGSNPFVPMGKFSSIVP-------VITHGSI 759
+ ++++ ++R+ ++++SDE+Y + FV GK S + +I
Sbjct: 188 SPNDVKKIVDISRDNKIILLSDEIY-------DNFVYEGKMRSTLEDSDWRDFLIYVNGF 240
Query: 758 SKGWSVPGWRTGWL 717
SK +S+ GWR G++
Sbjct: 241 SKTFSMTGWRLGYI 254
>sp|Q56232|AAT_THET8 Aspartate aminotransferase OS=Thermus thermophilus (strain
HB8 / ATCC 27634 / DSM 579) GN=aspC PE=1 SV=1
Length = 385
Score = 83 bits (204), Expect = 4e-015
Identities = 54/200 (27%), Positives = 94/200 (47%), Gaps = 6/200 (3%)
Frame = -1
Query: 1313 KAVVKAVICGNGNAYASSIGLPVAKDAVAEYLNRDLDNKLTGDDVFMTVGCKQAIELVVD 1134
K + + YA G+P ++A+AE R+ +T ++ +TVG KQA+ +
Sbjct: 50 KEAARRALAQGKTKYAPPAGIPELREALAEKFRRENGLSVTPEETIVTVGGKQALFNLFQ 109
Query: 1133 ILAKPEANILIPRPGFPADYVRSLFKKLEVRRYEVIPEKEFEIDLDSVKEMADKNTFAIF 954
+ P +++ P + + F V E +PE+ F D + V+ T A+
Sbjct: 110 AILDPGDEVIVLSPYWVSYPEMVRFAGGVVVEVETLPEEGFVPDPERVRRAITPRTKALV 169
Query: 953 IINPHNPNGNYYTEPHLEQLAKLARELGVMVVSDEVYRWTVFGSNPFVPMGKFSSIVP-- 780
+ +P+NP G Y + LE LA+LA E +VSDE+Y ++ F P + P
Sbjct: 170 VNSPNNPTGAVYPKEVLEALARLAVEHDFYLVSDEIYEHLLYEGEHFSP----GRVAPEH 225
Query: 779 VITHGSISKGWSVPGWRTGW 720
+T +K +++ GWR G+
Sbjct: 226 TLTVNGAAKAFAMTGWRIGY 245
>sp|P71348|Y286_HAEIN Uncharacterized aminotransferase HI_0286 OS=Haemophilus
influenzae GN=HI_0286 PE=3 SV=1
Length = 404
Score = 80 bits (195), Expect = 5e-014
Identities = 48/208 (23%), Positives = 95/208 (45%), Gaps = 4/208 (1%)
Frame = -1
Query: 1283 NGNAYASSIGLPVAKDAVAEYLNRDLDNKLTGDDVFMTVGCKQAIELVVDILAKPEANIL 1104
+ Y S GL A+ A+ +Y T +DV++ G + I + + L +L
Sbjct: 64 SAQGYCDSKGLYSARKAIVQYYQSKGILGATVNDVYIGNGVSELITMAMQALLNDGDEVL 123
Query: 1103 IPRPGFPADYVRSLFKKLEVRRYEVIPEKEFEIDLDSVKEMADKNTFAIFIINPHNPNGN 924
+P P +P + Y + + +D +K + T AI IINP+NP G
Sbjct: 124 VPMPDYPLWTAAVTLSGGKAVHYLCDEDANWFPTIDDIKAKVNAKTKAIVIINPNNPTGA 183
Query: 923 YYTEPHLEQLAKLARELGVMVVSDEVYRWTVFGSNPFVPMGKFSSIVPVITHGSISKGWS 744
Y++ L+++ ++AR+ +++ +DE+Y ++ + + + +T +SK +
Sbjct: 184 VYSKELLQEIVEIARQNNLIIFADEIYDKILYDGAVHHHIAALAPDLLTVTLNGLSKAYR 243
Query: 743 VPGWRTGWLAM----HDLNGVFKSTKVL 672
V G+R GW+ + H+ G + +L
Sbjct: 244 VAGFRQGWMILNGPKHNAKGYIEGLDML 271
>sp|A0LEA5|DAPAT_SYNFM LL-diaminopimelate aminotransferase OS=Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB) GN=dapL PE=1 SV=1
Length = 388
Score = 76 bits (185), Expect = 7e-013
Identities = 79/311 (25%), Positives = 125/311 (40%), Gaps = 23/311 (7%)
Frame = -1
Query: 1271 YASSIGLPVAKDAVAEYLNRDLDNKLTG-DDVFMTVGCKQAIELVVDILAKPEANILIPR 1095
Y S G+ K +VA + R +L +V +G K+ + + P L+P
Sbjct: 66 YPSYSGMNDFKVSVAGWYKRRFGVELDPLSEVLTLIGSKEGLAHFPLAVINPGDLALVPT 125
Query: 1094 PGFPADYVRSLFKKLEVRRYEVIPEKEFEIDLDSVKEMADKNTFAIFIINPHNPNGNYYT 915
P +P +V ++F E ++ E F DLDS+ + +FI P+NP G
Sbjct: 126 PAYPVYHVATMFAGGESYFMPLVRENGFLPDLDSIPADVARRAKVMFINYPNNPTGATAE 185
Query: 914 EPHLEQLAKLARELGVMVVSDEVYRWTVFGSNPFVPMGKFSSIVPV-ITHGSISKGWSVP 738
E++ ARE V+V D Y FG + + V + S+SK +++
Sbjct: 186 RDFFEKVIAFAREYDVIVCHDAAYTEMAFGGYRPLSFLELPGAGEVGVEFHSLSKTYNMT 245
Query: 737 GWRTGWLAMHDLNGVFKSTKVLKAANEFLEINSKPPTVIQAAIPTILEKTPQEFFDRRQS 558
GWR G+ V + + I+S +Q A T LE Q Q
Sbjct: 246 GWRLGF-------AVGNADILAGLGQVKSNIDSGAFNAVQWAGITALE-GDQGCVVEMQR 297
Query: 557 FLKDKVDIAYAKLKEI---PTLTCYMKPEACTFLWTELDPSHFVDIEDDQDFCNKLAKEE 387
K+++DI LK I P + P A ++W P + +DF + L +E
Sbjct: 298 IYKERLDILIEGLKRIGLHPEV-----PRATFYVWCPTPPGY-----SSKDFSSLLLREA 347
Query: 386 NLVVLPGIAFG 354
+V PG FG
Sbjct: 348 GIVATPGSGFG 358
>sp|Q972A2|AAT_SULTO Aspartate aminotransferase OS=Sulfolobus tokodaii GN=aspC
PE=3 SV=1
Length = 399
Score = 74 bits (179), Expect = 3e-012
Identities = 51/194 (26%), Positives = 95/194 (48%), Gaps = 17/194 (8%)
Frame = -1
Query: 1271 YASSIGLPVAKDAVAEYLNRDLDNKLTGDDVFMTVGCKQAIELVVDILAKPEANILIPRP 1092
Y S+ G+ + +AE+L+ ++ + ++V +T G K A+ L + P ++I P
Sbjct: 67 YTSAYGIDELRQKIAEHLSSKYES-VRKEEVIVTPGAKTALYLAFLLYINPGDEVIIFDP 125
Query: 1091 GF--PADYVRSLFKKLEVRRYEVIPEKEFEIDLDSVKEMADKNTFAIFIINPHNPNGNYY 918
F A+ V+ L + + F ++L ++ +K T I + NPHNP G +
Sbjct: 126 SFYSYAEVVKMLGGVPVYVKMKFNESTGFSLNLSELESKINKKTKMIVLNNPHNPTGMVF 185
Query: 917 TEPHLEQLAKLARELGVMVVSDEVYRWTVFGSNPFVPMGKFSSIVP-------VITHGSI 759
+E+L ++ +E V+++SDE+Y + F+ GK S++ VI
Sbjct: 186 DPIEIEKLMEITKEKKVLLLSDEIYDY-------FIYEGKMKSVLEDPDWRDYVIYVNGF 238
Query: 758 SKGWSVPGWRTGWL 717
SK +S+ GWR G++
Sbjct: 239 SKTFSMTGWRLGYV 252
>sp|Q0P5G4|KAT3_BOVIN Kynurenine--oxoglutarate transaminase 3 OS=Bos taurus
GN=CCBL2 PE=2 SV=1
Length = 455
Score = 67 bits (163), Expect = 2e-010
Identities = 34/100 (34%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
Frame = -1
Query: 1016 EFEIDLDSVKEMADKNTFAIFIINPHNPNGNYYTEPHLEQLAKLARELGVMVVSDEVYRW 837
++ +D + + T AI + PHNP G YT+ L+ +A L + + +SDEVY W
Sbjct: 192 DWTLDPQELASKFNSKTKAIILNTPHNPLGKVYTKEELQVIADLCIKYDTLCISDEVYEW 251
Query: 836 TVFGSNPFVPMGKFSSI-VPVITHGSISKGWSVPGWRTGW 720
V+ N + F + IT GS K +SV GW+ GW
Sbjct: 252 LVYTGNKHFKIATFPGMWERTITIGSAGKTFSVTGWKLGW 291
>sp|Q6YP21|KAT3_HUMAN Kynurenine--oxoglutarate transaminase 3 OS=Homo sapiens
GN=CCBL2 PE=1 SV=1
Length = 454
Score = 67 bits (163), Expect = 2e-010
Identities = 33/100 (33%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
Frame = -1
Query: 1016 EFEIDLDSVKEMADKNTFAIFIINPHNPNGNYYTEPHLEQLAKLARELGVMVVSDEVYRW 837
++ +D ++ + T AI + PHNP G Y L+ +A L + + +SDEVY W
Sbjct: 192 DWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEW 251
Query: 836 TVFGSNPFVPMGKFSSI-VPVITHGSISKGWSVPGWRTGW 720
V+ N + + F + IT GS K +SV GW+ GW
Sbjct: 252 LVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGW 291
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,366,676,449
Number of Sequences: 518415
Number of Extensions: 41366676449
Number of Successful Extensions: 294470065
Number of sequences better than 0.0: 0
|
