BLASTX 7.6.2
Query= UN10020 /QuerySize=970
(969 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|A5PK19|MTL13_BOVIN Methyltransferase-like protein 13 OS=Bos t... 107 2e-022
sp|Q91YR5|MTL13_MOUSE Methyltransferase-like protein 13 OS=Mus m... 104 1e-021
sp|Q8N6R0|MTL13_HUMAN Methyltransferase-like protein 13 OS=Homo ... 104 2e-021
sp|O60344|ECE2_HUMAN Endothelin-converting enzyme 2 OS=Homo sapi... 103 3e-021
sp|Q10711|ECE2_BOVIN Endothelin-converting enzyme 2 OS=Bos tauru... 99 4e-020
sp|A5WVX1|MTL13_DANRE Methyltransferase-like protein 13 OS=Danio... 98 7e-020
sp|Q9VIK9|MTL13_DROME Methyltransferase-like protein 13 OS=Droso... 98 7e-020
sp|Q29LW1|MTL13_DROPS Methyltransferase-like protein 13 OS=Droso... 98 7e-020
sp|Q80Z60|ECE2_MOUSE Endothelin-converting enzyme 2 OS=Mus muscu... 97 2e-019
sp|Q6NTR1|MTL13_XENLA Methyltransferase-like protein 13 OS=Xenop... 84 1e-015
>sp|A5PK19|MTL13_BOVIN Methyltransferase-like protein 13 OS=Bos taurus
GN=METTL13 PE=2 SV=1
Length = 699
Score = 107 bits (265), Expect = 2e-022
Identities = 57/157 (36%), Positives = 91/157 (57%), Gaps = 5/157 (3%)
Frame = +1
Query: 91 YGDAHYWDARYVQ-DALSFDWYQRYSSLRPFVRSFVPTSSRVLMVGCGNSLMSEDMVKDG 267
+G YW+ + Q +F+WY Y L + ++ +VL+VGCGNS +SE + G
Sbjct: 11 FGSVDYWEKFFQQRGKKAFEWYGTYLELCGVLHKYIKPREKVLVVGCGNSELSEQLYDVG 70
Query: 268 YEDIMNVDISSVAVEMMQTKYAS-VPQLKYMQMDVRDMSYFADDSFGTVVDKGTLDSLMC 444
Y+DI+N+DIS V ++ M+ + AS P++ +++MD+ M F D SF V+DKGTLD+++
Sbjct: 71 YQDIVNIDISEVVIKQMKERNASRRPRMSFLKMDMTQME-FPDASFQVVLDKGTLDAVLT 129
Query: 445 GTDAPL--SASRMLGEVSRLIKPGGTYFLITYGDPKV 549
+ RML EV R+++ GG Y I+ V
Sbjct: 130 DEEEKTLQQVDRMLAEVGRVLQVGGRYLCISLAQAHV 166
>sp|Q91YR5|MTL13_MOUSE Methyltransferase-like protein 13 OS=Mus musculus
GN=Mettl13 PE=1 SV=1
Length = 698
Score = 104 bits (258), Expect = 1e-021
Identities = 53/151 (35%), Positives = 89/151 (58%), Gaps = 5/151 (3%)
Frame = +1
Query: 91 YGDAHYWDARYVQ-DALSFDWYQRYSSLRPFVRSFVPTSSRVLMVGCGNSLMSEDMVKDG 267
+G A YW+ + Q +F+WY Y L + ++ +VL++GCGNS +SE + G
Sbjct: 11 FGSADYWEKFFQQRGKTAFEWYGTYLELCEVLHKYIKPKEKVLVIGCGNSELSEQLYDVG 70
Query: 268 YEDIMNVDISSVAVEMMQTKYAS-VPQLKYMQMDVRDMSYFADDSFGTVVDKGTLDSLMC 444
Y+DI+N+DIS V ++ M+ + S P + +++MD+ + F D +F V+DKGTLD+++
Sbjct: 71 YQDIVNIDISEVVIKQMKERNGSRRPHMSFLKMDMTQLE-FPDATFQVVLDKGTLDAVLT 129
Query: 445 GTDAPL--SASRMLGEVSRLIKPGGTYFLIT 531
+ RML EV R+++ GG Y I+
Sbjct: 130 DEEEVTLRQVDRMLAEVGRVLQVGGRYLCIS 160
>sp|Q8N6R0|MTL13_HUMAN Methyltransferase-like protein 13 OS=Homo sapiens
GN=METTL13 PE=1 SV=1
Length = 699
Score = 104 bits (257), Expect = 2e-021
Identities = 55/151 (36%), Positives = 88/151 (58%), Gaps = 5/151 (3%)
Frame = +1
Query: 91 YGDAHYWDARYVQ-DALSFDWYQRYSSLRPFVRSFVPTSSRVLMVGCGNSLMSEDMVKDG 267
+G YW+ + Q +F+WY Y L + ++ +VL++GCGNS +SE + G
Sbjct: 11 FGSVDYWEKFFQQRGKKAFEWYGTYLELCGVLHKYIKPREKVLVIGCGNSELSEQLYDVG 70
Query: 268 YEDIMNVDISSVAVEMMQTKYAS-VPQLKYMQMDVRDMSYFADDSFGTVVDKGTLDSLMC 444
Y DI+N+DIS V ++ M+ A+ PQ+ +++MD+ M F D SF V+DKGTLD+++
Sbjct: 71 YRDIVNIDISEVVIKQMKECNATRRPQMSFLKMDMTQME-FPDASFQVVLDKGTLDAVLT 129
Query: 445 GTDAPL--SASRMLGEVSRLIKPGGTYFLIT 531
+ RML EV R+++ GG Y I+
Sbjct: 130 DEEEKTLQQVDRMLAEVGRVLQVGGRYLCIS 160
>sp|O60344|ECE2_HUMAN Endothelin-converting enzyme 2 OS=Homo sapiens GN=ECE2
PE=1 SV=4
Length = 883
Score = 103 bits (255), Expect = 3e-021
Identities = 51/129 (39%), Positives = 78/129 (60%), Gaps = 3/129 (2%)
Frame = +1
Query: 91 YGDAHYWDARY--VQDALSFDWYQRYSSLRPFVRSFVPTSSRVLMVGCGNSLMSEDMVKD 264
Y + YWD RY D+ +DW+ +SS R + + R+L++GCGNS +S ++
Sbjct: 20 YREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPEDRILVLGCGNSALSYELFLG 79
Query: 265 GYEDIMNVDISSVAVEMMQTKYASVPQLKYMQMDVRDMSYFADDSFGTVVDKGTLDSLMC 444
G+ ++ +VD SSV V MQ ++A VPQL++ MDVR + F SF V++KGTLD+L+
Sbjct: 80 GFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLD-FPSASFDVVLEKGTLDALLA 138
Query: 445 GTDAPLSAS 471
G P + S
Sbjct: 139 GERDPWTVS 147
>sp|Q10711|ECE2_BOVIN Endothelin-converting enzyme 2 OS=Bos taurus GN=ECE2 PE=1
SV=2
Length = 883
Score = 99 bits (245), Expect = 4e-020
Identities = 49/129 (37%), Positives = 76/129 (58%), Gaps = 3/129 (2%)
Frame = +1
Query: 91 YGDAHYWDARY--VQDALSFDWYQRYSSLRPFVRSFVPTSSRVLMVGCGNSLMSEDMVKD 264
Y + YWD RY D+ ++W+ +S R + + R+L++GCGNS +S ++
Sbjct: 20 YREVQYWDQRYQGAADSAPYEWFGDFSCFRDLLEPELRPLDRILVLGCGNSALSYELFLG 79
Query: 265 GYEDIMNVDISSVAVEMMQTKYASVPQLKYMQMDVRDMSYFADDSFGTVVDKGTLDSLMC 444
G+ D+ +VD SSV V M+ +YA VP L++ MDVR + F SF V++KGTLD+L+
Sbjct: 80 GFPDVTSVDYSSVVVAAMRARYAHVPTLRWETMDVRALG-FPSGSFDVVLEKGTLDALLT 138
Query: 445 GTDAPLSAS 471
G P + S
Sbjct: 139 GEQDPWTVS 147
>sp|A5WVX1|MTL13_DANRE Methyltransferase-like protein 13 OS=Danio rerio
GN=mettl13 PE=2 SV=1
Length = 690
Score = 98 bits (243), Expect = 7e-020
Identities = 58/174 (33%), Positives = 87/174 (50%), Gaps = 4/174 (2%)
Frame = +1
Query: 91 YGDAHYWDARY-VQDALSFDWYQRYSSLRPFVRSFVPTSSRVLMVGCGNSLMSEDMVKDG 267
+ A YW+ + + +F+WY Y+SL + ++ +VL+VGCGNS +SE + G
Sbjct: 11 FSSADYWERFFRKRGEKAFEWYGDYNSLCGVLHKYIKPRDKVLVVGCGNSELSEQLYDVG 70
Query: 268 YEDIMNVDISSVAVEMMQTKYAS-VPQLKYMQMDVRDMSYFADDSFGTVVDKGTLDSLMC 444
Y + N+DIS V M + A P L + Q+D F SF +DKGTLD++
Sbjct: 71 YRQLTNIDISETVVSHMNQRNAERRPDLSFQQLDATQTG-FESGSFQVTLDKGTLDAMAS 129
Query: 445 GTDAPLSASRMLGEVSRLIKPGGTYFLITYGDPKVRMPHLNPSVYHWKISLYII 606
D L A RML EV R++ GG Y IT V + V W + ++ +
Sbjct: 130 EEDGAL-AGRMLAEVGRVLAVGGRYVCITLAQEHVIKLAVEHFVKGWAVRVHCL 182
>sp|Q9VIK9|MTL13_DROME Methyltransferase-like protein 13 OS=Drosophila
melanogaster GN=CG2614 PE=2 SV=1
Length = 673
Score = 98 bits (243), Expect = 7e-020
Identities = 52/147 (35%), Positives = 83/147 (56%), Gaps = 5/147 (3%)
Frame = +1
Query: 91 YGDAHYWDARY-VQDALSFDWYQRYSSLRPFVRSFVPTSSRVLMVGCGNSLMSEDMVKDG 267
+ YW+ + + +F+WY Y L + ++ + R+LM+GCGNS +S DM G
Sbjct: 11 FAQTDYWNEFFKKRGEKAFEWYGEYLELCDQIHKYIKPADRILMLGCGNSKLSMDMYDTG 70
Query: 268 YEDIMNVDISSVAV-EMMQTKYASVPQLKYMQMDVRDMSYFADDSFGTVVDKGTLDSLMC 444
+ DI N+DIS +AV +M++ S P++K++QMD M+ F D+SF +DKGTLD+L
Sbjct: 71 FRDITNIDISPIAVKKMLELNAKSRPEMKFLQMDATAMT-FPDESFSVSLDKGTLDALFA 129
Query: 445 GTDAPLSA--SRMLGEVSRLIKPGGTY 519
+ A E+ R ++ GG Y
Sbjct: 130 DDEPETRAVVENYFKEILRTMRNGGRY 156
>sp|Q29LW1|MTL13_DROPS Methyltransferase-like protein 13 OS=Drosophila
pseudoobscura pseudoobscura GN=GA15401 PE=3 SV=1
Length = 673
Score = 98 bits (243), Expect = 7e-020
Identities = 54/152 (35%), Positives = 85/152 (55%), Gaps = 7/152 (4%)
Frame = +1
Query: 91 YGDAHYWDARY-VQDALSFDWYQRYSSLRPFVRSFVPTSSRVLMVGCGNSLMSEDMVKDG 267
+ YW+ + + +F+WY Y L + ++ ++LM+GCGNS +S DM
Sbjct: 11 FAQTDYWNEFFKKRGEKAFEWYGEYLDLCDHIHKYIKPVDKILMLGCGNSKLSMDMYDSE 70
Query: 268 YEDIMNVDISSVAV-EMMQTKYASVPQLKYMQMDVRDMSYFADDSFGTVVDKGTLDSLMC 444
Y DI N+DIS VAV +M++ + P +K++QMD M+ F D+SF +DKGTLD+L
Sbjct: 71 YRDITNIDISPVAVKKMLEQNARTRPDMKFLQMDATAMT-FPDESFSVALDKGTLDALFV 129
Query: 445 GTDAPLS---ASRMLGEVSRLIKPGGTYFLIT 531
DAP + E+ R ++ GG YF ++
Sbjct: 130 -DDAPETKAVVENYFKEILRTMRNGGRYFCVS 160
>sp|Q80Z60|ECE2_MOUSE Endothelin-converting enzyme 2 OS=Mus musculus GN=Ece2
PE=2 SV=2
Length = 881
Score = 97 bits (239), Expect = 2e-019
Identities = 47/131 (35%), Positives = 76/131 (58%), Gaps = 3/131 (2%)
Frame = +1
Query: 85 YNYGDAHYWDARY--VQDALSFDWYQRYSSLRPFVRSFVPTSSRVLMVGCGNSLMSEDMV 258
+ Y YWD RY D+ ++W+ ++S R + + R+L++GCGNS +S ++
Sbjct: 18 FQYRQVQYWDQRYKDAADSGPYEWFGDFASFRALLEPELCPEDRILVLGCGNSALSYELF 77
Query: 259 KDGYEDIMNVDISSVAVEMMQTKYASVPQLKYMQMDVRDMSYFADDSFGTVVDKGTLDSL 438
G+ ++ +VD S V V MQ +YA VP L++ MDVR + F SF V++KGTLD++
Sbjct: 78 LGGFPNVTSVDYSPVVVAAMQVRYAHVPSLRWETMDVRALD-FPSGSFDVVLEKGTLDAM 136
Query: 439 MCGTDAPLSAS 471
+ G P + S
Sbjct: 137 LAGEPDPWNVS 147
>sp|Q6NTR1|MTL13_XENLA Methyltransferase-like protein 13 OS=Xenopus laevis
GN=mettl13 PE=2 SV=1
Length = 693
Score = 84 bits (207), Expect = 1e-015
Identities = 45/166 (27%), Positives = 86/166 (51%), Gaps = 5/166 (3%)
Frame = +1
Query: 64 DVSSCNTYNYGDAHYWDARY-VQDALSFDWYQRYSSLRPFVRSFVPTSSRVLMVGCGNSL 240
D+ ++ + YW+ + + +F+WY Y L + ++ +V +VGCGNS
Sbjct: 2 DLLPKSSKEFAAPEYWEQFFRRRGERAFEWYGGYLELCGLLHKYIKPRDKVFVVGCGNSE 61
Query: 241 MSEDMVKDGYEDIMNVDISSVAVEMMQTKYAS-VPQLKYMQMDVRDMSYFADDSFGTVVD 417
+SE + G +++ N+D+S V + M + ++ P + + MD + F D F V+D
Sbjct: 62 LSEQLYDAGCQNLTNIDVSEVVIRQMNERNSNRRPNMTFQVMDATQTT-FDDSCFQAVLD 120
Query: 418 KGTLDSLMCGTDAPL--SASRMLGEVSRLIKPGGTYFLITYGDPKV 549
KGTLD++M TD +A +++ E+ R++ GG + ++ V
Sbjct: 121 KGTLDAIMTDTDKGTLETADKLMSEIGRVLTCGGRFLCVSLAQAHV 166
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,366,676,449
Number of Sequences: 518415
Number of Extensions: 41366676449
Number of Successful Extensions: 294470065
Number of sequences better than 0.0: 0
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