BLASTX 7.6.2
Query= UN10088 /QuerySize=983
(982 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9SKI2|VPS2A_ARATH Vacuolar protein sorting-associated protei... 421 4e-117
sp|O43633|CHM2A_HUMAN Charged multivesicular body protein 2a OS=... 247 1e-064
sp|Q9DB34|CHM2A_MOUSE Charged multivesicular body protein 2a OS=... 247 1e-064
sp|Q54DB1|CM2A2_DICDI Charged multivesicular body protein 2a hom... 243 1e-063
sp|Q7ZW25|CHM2A_DANRE Charged multivesicular body protein 2a OS=... 240 1e-062
sp|Q6IP52|CHM2A_XENLA Charged multivesicular body protein 2a OS=... 237 1e-061
sp|Q6DFS6|CHM2A_XENTR Charged multivesicular body protein 2a OS=... 236 2e-061
sp|Q5ZHN1|CHM2A_CHICK Charged multivesicular body protein 2a OS=... 230 2e-059
sp|P36108|DID4_YEAST DOA4-independent degradation protein 4 OS=S... 202 4e-051
sp|Q941D5|VPS2C_ARATH Vacuolar protein sorting-associated protei... 178 7e-044
sp|Q0WTY4|VPS2B_ARATH Vacuolar protein sorting-associated protei... 172 4e-042
sp|O14177|YDS1_SCHPO Uncharacterized protein C4F8.01 OS=Schizosa... 166 3e-040
sp|Q66IV6|CH2BB_XENLA Charged multivesicular body protein 2b-B O... 144 9e-034
sp|Q5F3A2|CHM2B_CHICK Charged multivesicular body protein 2b OS=... 143 2e-033
sp|Q7SYR0|CH2BA_XENLA Charged multivesicular body protein 2b-A O... 142 4e-033
sp|Q9UQN3|CHM2B_HUMAN Charged multivesicular body protein 2b OS=... 141 7e-033
sp|Q5RAV2|CHM2B_PONAB Charged multivesicular body protein 2b OS=... 141 7e-033
sp|Q6NXD2|CHM2B_DANRE Charged multivesicular body protein 2b OS=... 141 1e-032
sp|Q6NVL7|CHM2B_XENTR Charged multivesicular body protein 2b OS=... 141 1e-032
sp|Q3SX42|CHM2B_BOVIN Charged multivesicular body protein 2b OS=... 140 2e-032
>sp|Q9SKI2|VPS2A_ARATH Vacuolar protein sorting-associated protein 2 homolog 1
OS=Arabidopsis thaliana GN=VPS2.1 PE=2 SV=2
Length = 225
Score = 421 bits (1082), Expect = 4e-117
Identities = 220/225 (97%), Positives = 221/225 (98%)
Frame = +1
Query: 151 MMNSIFGKRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAV 330
MMNSIFGKRKTPAELLRENKRMLDKSIR+IERERQGLQTQEKKLI EIKKTAKQGQMGAV
Sbjct: 1 MMNSIFGKRKTPAELLRENKRMLDKSIREIERERQGLQTQEKKLINEIKKTAKQGQMGAV 60
Query: 331 KVMAKDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNL 510
KVMAKDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNL
Sbjct: 61 KVMAKDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNL 120
Query: 511 PSLQKIMQEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQEL 690
PSLQKIMQEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQEL
Sbjct: 121 PSLQKIMQEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQEL 180
Query: 691 VNAPSGAVAAPAAKNKVVQAEAAGAEDGGGIDSDLQARLDNLRKM 825
VNAPSGAVA PAAKNKVVQAEA GAED GGIDSDLQARLDNLRKM
Sbjct: 181 VNAPSGAVAVPAAKNKVVQAEATGAEDSGGIDSDLQARLDNLRKM 225
>sp|O43633|CHM2A_HUMAN Charged multivesicular body protein 2a OS=Homo sapiens
GN=CHMP2A PE=1 SV=1
Length = 222
Score = 247 bits (629), Expect = 1e-064
Identities = 126/223 (56%), Positives = 170/223 (76%), Gaps = 4/223 (1%)
Frame = +1
Query: 154 MNSIFGKRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVK 333
M+ +FG+RKTP ELLR+N+R L++++R+++RERQ L+TQEKK+I +IKK AKQGQM AV+
Sbjct: 1 MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVR 60
Query: 334 VMAKDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLP 513
+MAKDL+RTR + KF +++ +Q VSL+IQTLKS +M +AMKGVTKAMG MNRQ+ LP
Sbjct: 61 IMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLP 120
Query: 514 SLQKIMQEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELV 693
+QKIM EFERQ E M+M E+M DAIDDA+ +E+EEE++ +VSQVLDE+G+ + EL
Sbjct: 121 QIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELS 180
Query: 694 NAPS-GAVAAPAAKNKVVQAEAAGAEDGGGIDSDLQARLDNLR 819
N PS G + AA K +A A+ D D+DL+ RL NLR
Sbjct: 181 NLPSTGGSLSVAAGGKKAEAAASALADA---DADLEERLKNLR 220
>sp|Q9DB34|CHM2A_MOUSE Charged multivesicular body protein 2a OS=Mus musculus
GN=Chmp2a PE=1 SV=1
Length = 222
Score = 247 bits (629), Expect = 1e-064
Identities = 126/223 (56%), Positives = 170/223 (76%), Gaps = 4/223 (1%)
Frame = +1
Query: 154 MNSIFGKRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVK 333
M+ +FG+RKTP ELLR+N+R L++++R+++RERQ L+TQEKK+I +IKK AKQGQM AV+
Sbjct: 1 MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVR 60
Query: 334 VMAKDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLP 513
+MAKDL+RTR + KF +++ +Q VSL+IQTLKS +M +AMKGVTKAMG MNRQ+ LP
Sbjct: 61 IMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLP 120
Query: 514 SLQKIMQEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELV 693
+QKIM EFERQ E M+M E+M DAIDDA+ +E+EEE++ +VSQVLDE+G+ + EL
Sbjct: 121 QIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELS 180
Query: 694 NAPS-GAVAAPAAKNKVVQAEAAGAEDGGGIDSDLQARLDNLR 819
N PS G + AA K +A A+ D D+DL+ RL NLR
Sbjct: 181 NLPSTGGSLSVAAGGKKAEATASALADA---DADLEERLKNLR 220
>sp|Q54DB1|CM2A2_DICDI Charged multivesicular body protein 2a homolog 2
OS=Dictyostelium discoideum GN=chmp2a2 PE=3 SV=1
Length = 198
Score = 243 bits (620), Expect = 1e-063
Identities = 119/193 (61%), Positives = 160/193 (82%)
Frame = +1
Query: 163 IFGKRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVKVMA 342
+FGK+KTP E+LREN+R L+KS+R+I+RER LQ QEKK+I +IKK AKQGQM + K+MA
Sbjct: 3 LFGKQKTPKEVLRENQRNLNKSMREIDRERVALQNQEKKIILDIKKMAKQGQMNSAKIMA 62
Query: 343 KDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLPSLQ 522
KDL+RTR+ I+KFY++K+QLQ VSLRIQTL+STQAM EAMKGVTKAM MNRQMNLP
Sbjct: 63 KDLVRTRYHIQKFYEMKTQLQAVSLRIQTLQSTQAMAEAMKGVTKAMITMNRQMNLPQFT 122
Query: 523 KIMQEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELVNAP 702
KIM EFE+Q++KM+M E+M D +D +E D EEE+++++++QVLDEIGID+ +LV+AP
Sbjct: 123 KIMMEFEQQSDKMDMKEEMMNDTMDQVMEQDGEEEQSQEILNQVLDEIGIDLASQLVDAP 182
Query: 703 SGAVAAPAAKNKV 741
+ + A+K++V
Sbjct: 183 TTVGTSVASKHQV 195
>sp|Q7ZW25|CHM2A_DANRE Charged multivesicular body protein 2a OS=Danio rerio
GN=chmp2a PE=2 SV=1
Length = 220
Score = 240 bits (611), Expect = 1e-062
Identities = 121/222 (54%), Positives = 169/222 (76%), Gaps = 8/222 (3%)
Frame = +1
Query: 154 MNSIFGKRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVK 333
M S+FG+RKTP E+LR+N+R L++++RD++RERQ L+ QEKK+I +IKK AKQGQM AVK
Sbjct: 1 MESLFGRRKTPEEMLRQNQRALNRAMRDLDRERQRLEQQEKKIIADIKKMAKQGQMDAVK 60
Query: 334 VMAKDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLP 513
+MAKDL+RTR ++KF +++ +Q VSL+IQTLKS +M +AMKGVTKAM MNRQ+ LP
Sbjct: 61 IMAKDLVRTRRYVKKFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLP 120
Query: 514 SLQKIMQEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELV 693
+QKIM EFERQ+E M+M E+M DAIDDA+ +++EEE++ +VSQVLDE+G+ ++ EL
Sbjct: 121 QIQKIMMEFERQSEIMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLSDELS 180
Query: 694 NAPS--GAVAAPAAKNKVVQAEAAGAEDGGGIDSDLQARLDN 813
N P+ G+++ A K Q A A D+DL+ RL+N
Sbjct: 181 NLPATGGSLSVAAGKKAEPQPTLADA------DADLEERLNN 216
>sp|Q6IP52|CHM2A_XENLA Charged multivesicular body protein 2a OS=Xenopus laevis
GN=chmp2a PE=2 SV=1
Length = 220
Score = 237 bits (604), Expect = 1e-061
Identities = 120/220 (54%), Positives = 167/220 (75%), Gaps = 4/220 (1%)
Frame = +1
Query: 154 MNSIFGKRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVK 333
M +FG+RKTP ELLR+N+R L++++R+++RERQ L+ QEKK+I +IKK AKQGQM AVK
Sbjct: 1 MEFLFGRRKTPEELLRQNQRALNRAMRELDRERQKLEQQEKKIIADIKKMAKQGQMDAVK 60
Query: 334 VMAKDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLP 513
+MAKDL+RTR ++KF +++ +Q VSL+IQTLKS +M +AMKGVTKAM MNRQ+ LP
Sbjct: 61 IMAKDLVRTRRYVKKFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLP 120
Query: 514 SLQKIMQEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELV 693
+QKIM EFE+Q+E M+M E+M DAIDDA+ +++EEE++ +VSQVLDE+G+ + EL
Sbjct: 121 QIQKIMMEFEKQSEIMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLTDELS 180
Query: 694 NAPSGAVAAPAAKNKVVQAEAAGAEDGGGIDSDLQARLDN 813
N PS + A K +A AA A+ D+DL+ RL+N
Sbjct: 181 NLPSTGGSLSVAGAKKGEATAALAD----ADADLEERLNN 216
>sp|Q6DFS6|CHM2A_XENTR Charged multivesicular body protein 2a OS=Xenopus
tropicalis GN=chmp2a PE=2 SV=1
Length = 220
Score = 236 bits (601), Expect = 2e-061
Identities = 120/222 (54%), Positives = 167/222 (75%), Gaps = 8/222 (3%)
Frame = +1
Query: 154 MNSIFGKRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVK 333
M +FG+RKTP E+LR+N+R L+K++R+++RERQ L+ QEKK+I +IKK AKQGQM AVK
Sbjct: 1 MEFLFGRRKTPEEMLRQNQRALNKAMREMDRERQKLEQQEKKIIADIKKMAKQGQMDAVK 60
Query: 334 VMAKDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLP 513
+MAKDL+RTR ++KF +++ +Q VSL+IQTLKS +M +AMKGVTKAM MNRQ+ LP
Sbjct: 61 IMAKDLVRTRRYVKKFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLP 120
Query: 514 SLQKIMQEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELV 693
+QKIM EFE+Q+E M+M E+M DAIDDA+ +++EEE++ +VSQVLDE+G+ + EL
Sbjct: 121 QIQKIMMEFEKQSEIMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLTDELS 180
Query: 694 NAPS--GAVAAPAAKNKVVQAEAAGAEDGGGIDSDLQARLDN 813
N PS G+++ AK A A A D+DL+ RL+N
Sbjct: 181 NLPSTGGSLSVAGAKKGEPSAALADA------DADLEERLNN 216
>sp|Q5ZHN1|CHM2A_CHICK Charged multivesicular body protein 2a OS=Gallus gallus
GN=CHMP2A PE=2 SV=1
Length = 220
Score = 230 bits (585), Expect = 2e-059
Identities = 116/220 (52%), Positives = 163/220 (74%), Gaps = 4/220 (1%)
Frame = +1
Query: 154 MNSIFGKRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVK 333
M+ +FG+RKTP ELLR+N+R L +++R+++RERQ L+ QEKK+I +IKK AKQGQM AVK
Sbjct: 1 MDLLFGRRKTPEELLRQNQRALTRAMRELDRERQKLEAQEKKIIIDIKKMAKQGQMDAVK 60
Query: 334 VMAKDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLP 513
+MAKDL+RTR ++KF +++ +Q VSL+IQTLKS +M AMKGVTKAM MNRQ+ LP
Sbjct: 61 IMAKDLVRTRRYVKKFITMRANVQAVSLKIQTLKSNNSMALAMKGVTKAMATMNRQLKLP 120
Query: 514 SLQKIMQEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELV 693
+QKIM EFE+Q M+M E+M DAIDDA+ +++EEE++ +VSQVLDE+G+++ EL
Sbjct: 121 QIQKIMMEFEKQAGIMDMKEELMNDAIDDAMGDEDDEEESDAVVSQVLDELGLNLTDELA 180
Query: 694 NAPSGAVAAPAAKNKVVQAEAAGAEDGGGIDSDLQARLDN 813
P + A + + +A AA A+ D+DL+ RL N
Sbjct: 181 TLPPPGGSLAAGEGRAAEAAAALAD----ADADLEERLKN 216
>sp|P36108|DID4_YEAST DOA4-independent degradation protein 4 OS=Saccharomyces
cerevisiae GN=DID4 PE=1 SV=2
Length = 232
Score = 202 bits (512), Expect = 4e-051
Identities = 107/225 (47%), Positives = 159/225 (70%), Gaps = 6/225 (2%)
Frame = +1
Query: 163 IFGKRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVKVMA 342
+FGK TP E L++N+R L+++ R++ERE++ L+ Q+KKL++EIKK+AK GQ+ A KV A
Sbjct: 7 VFGKNVTPQERLKKNQRALERTQRELEREKRKLELQDKKLVSEIKKSAKNGQVAAAKVQA 66
Query: 343 KDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLPSLQ 522
KDL+RTR+ I+KF +K+QLQ +SLRIQ ++S+ M +M T + MNR MNLP LQ
Sbjct: 67 KDLVRTRNYIQKFDNMKAQLQAISLRIQAVRSSDQMTRSMSEATGLLAGMNRTMNLPQLQ 126
Query: 523 KIMQEFERQNEKMEMVSEVMGDAIDDALEGDE--EEEETEDLVSQVLDEIGIDINQELVN 696
+I EFE+Q++ M E M +AID+ + GDE E+EE +++V++VLDEIG+D+N +L +
Sbjct: 127 RISMEFEKQSDLMGQRQEFMDEAIDNVM-GDEVDEDEEADEIVNKVLDEIGVDLNSQLQS 185
Query: 697 APSGAVA-APAAKNK--VVQAEAAGAEDGGGIDSDLQARLDNLRK 822
P V+ AP A+ + + AG+E G D DLQARL+ L+K
Sbjct: 186 TPQNLVSNAPIAETAMGIPEPIGAGSEFHGNPDDDLQARLNTLKK 230
>sp|Q941D5|VPS2C_ARATH Vacuolar protein sorting-associated protein 2 homolog 3
OS=Arabidopsis thaliana GN=VPS2.3 PE=2 SV=1
Length = 210
Score = 178 bits (450), Expect = 7e-044
Identities = 86/192 (44%), Positives = 133/192 (69%)
Frame = +1
Query: 160 SIFGKRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVKVM 339
+IF K+ P E+LRE+KR + ++ R IE+E LQ++EKKL+ EIK+TAK G GA K++
Sbjct: 2 NIFTKKPNPREVLRESKREMTQATRGIEKEIGSLQSEEKKLVLEIKRTAKSGNEGATKIL 61
Query: 340 AKDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLPSL 519
A+ LIR R QI ++Q++G++ Q + + ++ M+G TKAM M++ M+
Sbjct: 62 ARQLIRLRQQIANLQGSRAQMRGIATHTQAMHAHTSVAAGMQGATKAMAAMSKNMDPAKQ 121
Query: 520 QKIMQEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELVNA 699
K+M+EF++Q+ +M+M +E+M D+IDDAL+ DE E+ETEDL +QVLDEIGIDI +L +A
Sbjct: 122 AKVMREFQKQSAQMDMTTEMMSDSIDDALDNDEAEDETEDLTNQVLDEIGIDIASQLSSA 181
Query: 700 PSGAVAAPAAKN 735
P G + A++
Sbjct: 182 PKGKIGGKKAED 193
>sp|Q0WTY4|VPS2B_ARATH Vacuolar protein sorting-associated protein 2 homolog 2
OS=Arabidopsis thaliana GN=VPS2.2 PE=2 SV=2
Length = 222
Score = 172 bits (435), Expect = 4e-042
Identities = 90/221 (40%), Positives = 139/221 (62%), Gaps = 1/221 (0%)
Frame = +1
Query: 160 SIFGKRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVKVM 339
+IF K+ TP + LR +KR + + R IERE LQ +EK+L+ EIKKTAK G A K++
Sbjct: 2 NIFKKKTTPKDALRTSKREMAVATRGIEREITSLQLEEKRLVAEIKKTAKTGNEAATKIL 61
Query: 340 AKDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLPSL 519
A+ L+R R QI ++Q++GV+ Q L ++ ++ MKG TKAM MN+QM
Sbjct: 62 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 121
Query: 520 QKIMQEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELVNA 699
K++++F++Q+ +++M E+M +AID+ L+ DE EEETEDL +QVLDEIG+ + +L +A
Sbjct: 122 AKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 181
Query: 700 PSGAVAAPAAKNKVVQAEAAGAEDGGGIDSDLQARLDNLRK 822
P G +A A A + +D +L+ RL +LR+
Sbjct: 182 PKGRIATKTAAPPASTAATNKNSESSEVD-ELEKRLASLRR 221
>sp|O14177|YDS1_SCHPO Uncharacterized protein C4F8.01 OS=Schizosaccharomyces
pombe GN=SPAC4F8.01 PE=2 SV=2
Length = 210
Score = 166 bits (419), Expect = 3e-040
Identities = 81/192 (42%), Positives = 136/192 (70%), Gaps = 1/192 (0%)
Frame = +1
Query: 163 IFGKRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVKVMA 342
+FG K+P E LR ++R L ++ R+++RER L +E+ LI EIK +AK G GA ++ A
Sbjct: 7 LFGGGKSPQEQLRAHQRSLGRAERELDRERTKLDQRERALIQEIKGSAKAGNTGAARIQA 66
Query: 343 KDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLPSLQ 522
+DL+R R+ +K K+QLQ +SLR+QT+++++ M ++M+G T+ + MN+ MN+P++
Sbjct: 67 RDLMRLRNSRKKMMNAKTQLQAISLRLQTMRTSEQMMQSMRGATRLLTGMNKSMNIPAMA 126
Query: 523 KIMQEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELVNAP 702
+I Q+FER+NE ME E++ + +DDALE +++EEE ++LV++VLDEIG+D++Q L +A
Sbjct: 127 RITQQFERENEIMEQRQEMIDENMDDALE-EDDEEEADELVNKVLDEIGVDLSQGLPDAA 185
Query: 703 SGAVAAPAAKNK 738
+ P K +
Sbjct: 186 TQIGTVPELKTE 197
>sp|Q66IV6|CH2BB_XENLA Charged multivesicular body protein 2b-B OS=Xenopus
laevis GN=chmp2b-b PE=2 SV=1
Length = 214
Score = 144 bits (363), Expect = 9e-034
Identities = 77/197 (39%), Positives = 121/197 (61%), Gaps = 3/197 (1%)
Frame = +1
Query: 172 KRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVKVMAKDL 351
K+KT +++RE + L + R I R+R L+ QEK+L EIKK AK G A +V+AK L
Sbjct: 6 KKKTVDDIIREQNKELRGTQRAITRDRAALEKQEKQLEMEIKKMAKTGNKDACRVLAKQL 65
Query: 352 IRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLPSLQKIM 531
++ R Q + Y + S++ +S + + + S M AM K M +N++M+ + M
Sbjct: 66 VQLRKQKTRTYAVSSKVTSMSTQTKVMSSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTM 125
Query: 532 QEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELVNAPSGA 711
Q F+++N KMEM E++ D +DD + E+EEE++D+V+QVLDEIGI+I+ ++ APS A
Sbjct: 126 QNFQKENMKMEMTDEMINDTLDDIFDASEDEEESQDIVNQVLDEIGIEISGKMAKAPSAA 185
Query: 712 VAAP---AAKNKVVQAE 753
P AAK+K + E
Sbjct: 186 KGLPSTSAAKSKGISDE 202
>sp|Q5F3A2|CHM2B_CHICK Charged multivesicular body protein 2b OS=Gallus gallus
GN=CHMP2B PE=2 SV=1
Length = 214
Score = 143 bits (360), Expect = 2e-033
Identities = 73/186 (39%), Positives = 116/186 (62%)
Frame = +1
Query: 172 KRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVKVMAKDL 351
K+KT ++++E R L + R I R+R L+ QE++L EIKK AK G A KV+AK L
Sbjct: 6 KKKTVDDIIKEQNRELRGTQRTITRDRAALEKQERQLELEIKKMAKTGNKEACKVLAKQL 65
Query: 352 IRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLPSLQKIM 531
++ R Q + Y + S++ +S + + + S M AM K M +N++M+ + M
Sbjct: 66 VQLRKQKNRTYAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTM 125
Query: 532 QEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELVNAPSGA 711
Q F+++N KMEM E++ D +DD + +EEEE++D+V+QVLDEIGI+I+ ++ APS A
Sbjct: 126 QNFQKENMKMEMTEEMINDTLDDIFDASDEEEESQDIVNQVLDEIGIEISGKMAKAPSAA 185
Query: 712 VAAPAA 729
P+A
Sbjct: 186 RGLPSA 191
>sp|Q7SYR0|CH2BA_XENLA Charged multivesicular body protein 2b-A OS=Xenopus
laevis GN=chmp2b-a PE=2 SV=1
Length = 214
Score = 142 bits (357), Expect = 4e-033
Identities = 72/186 (38%), Positives = 115/186 (61%)
Frame = +1
Query: 172 KRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVKVMAKDL 351
K+KT +++++ + L R I R+R L+ QEK+L EIKK AK G A KV+AK L
Sbjct: 6 KKKTVDDIIKDQNKELKGQQRAITRDRTALEKQEKQLEMEIKKMAKAGNKDACKVLAKQL 65
Query: 352 IRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLPSLQKIM 531
++ R Q + Y + S++ +S + + + S M AM K M +N++M+ + M
Sbjct: 66 VQLRKQKTRTYAVSSKVTSMSTQTKVMSSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTM 125
Query: 532 QEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELVNAPSGA 711
Q F+++N KMEM E++ D +DD + E+EEE++D+V+QVLDEIGI+I+ ++ APS A
Sbjct: 126 QNFQKENMKMEMTEEMINDTLDDIFDASEDEEESQDIVNQVLDEIGIEISGKMAKAPSAA 185
Query: 712 VAAPAA 729
P+A
Sbjct: 186 KGLPSA 191
>sp|Q9UQN3|CHM2B_HUMAN Charged multivesicular body protein 2b OS=Homo sapiens
GN=CHMP2B PE=1 SV=1
Length = 213
Score = 141 bits (355), Expect = 7e-033
Identities = 73/186 (39%), Positives = 117/186 (62%)
Frame = +1
Query: 172 KRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVKVMAKDL 351
K+KT ++++E R L + R I R+R L+ QEK+L EIKK AK G A KV+AK L
Sbjct: 6 KKKTVDDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVLAKQL 65
Query: 352 IRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLPSLQKIM 531
+ R Q + + + S++ +S + + + S M AM K M +N++M+ + M
Sbjct: 66 VHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTM 125
Query: 532 QEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELVNAPSGA 711
Q F+++N KMEM E++ D +DD +G ++EEE++D+V+QVLDEIGI+I+ ++ APS A
Sbjct: 126 QNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKAPSAA 185
Query: 712 VAAPAA 729
+ P+A
Sbjct: 186 RSLPSA 191
>sp|Q5RAV2|CHM2B_PONAB Charged multivesicular body protein 2b OS=Pongo abelii
GN=CHMP2B PE=2 SV=1
Length = 213
Score = 141 bits (355), Expect = 7e-033
Identities = 73/186 (39%), Positives = 117/186 (62%)
Frame = +1
Query: 172 KRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVKVMAKDL 351
K+KT ++++E R L + R I R+R L+ QEK+L EIKK AK G A KV+AK L
Sbjct: 6 KKKTVDDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVLAKQL 65
Query: 352 IRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLPSLQKIM 531
+ R Q + + + S++ +S + + + S M AM K M +N++M+ + M
Sbjct: 66 VHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTM 125
Query: 532 QEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELVNAPSGA 711
Q F+++N KMEM E++ D +DD +G ++EEE++D+V+QVLDEIGI+I+ ++ APS A
Sbjct: 126 QNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKAPSAA 185
Query: 712 VAAPAA 729
+ P+A
Sbjct: 186 RSLPSA 191
>sp|Q6NXD2|CHM2B_DANRE Charged multivesicular body protein 2b OS=Danio rerio
GN=chmp2b PE=2 SV=1
Length = 214
Score = 141 bits (353), Expect = 1e-032
Identities = 75/200 (37%), Positives = 121/200 (60%), Gaps = 4/200 (2%)
Frame = +1
Query: 172 KRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVKVMAKDL 351
K+KT ++++E + L + R I R+R L+ QEK+L EIKK AK G A KV+AK L
Sbjct: 6 KKKTVDDVIKEQNKELRGTQRQIARDRTALEKQEKQLEMEIKKMAKTGNRDACKVLAKQL 65
Query: 352 IRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLPSLQKIM 531
++ R Q + Y + S++ +S + + + S M AM TK M +N++M+ + +
Sbjct: 66 VQVRKQKTRTYAVSSKVTSMSTQTKLMNSQMKMAGAMATTTKTMQAVNKKMDPKKTMQTL 125
Query: 532 QEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELVNAPSGA 711
Q F+++ KM+M E+M D +D+ E +EEE++D+V+QVLDEIGI+I+ ++ +APS A
Sbjct: 126 QNFQKETAKMDMTEEMMNDTLDEIFEDSGDEEESQDIVNQVLDEIGIEISGKMAHAPSAA 185
Query: 712 VAAPAAKNKVVQAEAAGAED 771
P+A A+A G D
Sbjct: 186 RKTPSA----ATAKADGISD 201
>sp|Q6NVL7|CHM2B_XENTR Charged multivesicular body protein 2b OS=Xenopus
tropicalis GN=chmp2b PE=2 SV=1
Length = 214
Score = 141 bits (353), Expect = 1e-032
Identities = 71/185 (38%), Positives = 115/185 (62%)
Frame = +1
Query: 172 KRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVKVMAKDL 351
K+KT +++RE + L + R I R+R L+ QEK+L EIKK AK G A +V+AK L
Sbjct: 6 KKKTVDDIIREQNKELRGTQRAITRDRAALEKQEKQLEMEIKKMAKAGNKDACRVLAKQL 65
Query: 352 IRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLPSLQKIM 531
++ R Q + Y + S++ +S + + + S M AM K M +N++M+ + M
Sbjct: 66 VQLRKQKTRTYAVSSKVTSMSTQTKVMSSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTM 125
Query: 532 QEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELVNAPSGA 711
Q F+++N KMEM E++ D +DD + ++EEE++D+V+QVLDEIGI+I+ ++ APS A
Sbjct: 126 QNFQKENMKMEMTEEMINDTLDDIFDASDDEEESQDIVNQVLDEIGIEISGKMAKAPSAA 185
Query: 712 VAAPA 726
P+
Sbjct: 186 KGLPS 190
>sp|Q3SX42|CHM2B_BOVIN Charged multivesicular body protein 2b OS=Bos taurus
GN=CHMP2B PE=2 SV=1
Length = 213
Score = 140 bits (352), Expect = 2e-032
Identities = 72/186 (38%), Positives = 117/186 (62%)
Frame = +1
Query: 172 KRKTPAELLRENKRMLDKSIRDIERERQGLQTQEKKLITEIKKTAKQGQMGAVKVMAKDL 351
K+KT ++++E R L + R I R+R L+ QEK+L EIKK AK G A +V+AK L
Sbjct: 6 KKKTVDDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACRVLAKQL 65
Query: 352 IRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLPSLQKIM 531
+ R Q + + + S++ +S + + + S M AM K M +N++M+ + M
Sbjct: 66 VHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTM 125
Query: 532 QEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELVNAPSGA 711
Q F+++N KMEM E++ D +DD +G ++EEE++D+V+QVLDEIGI+I+ ++ APS A
Sbjct: 126 QNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKAPSAA 185
Query: 712 VAAPAA 729
+ P+A
Sbjct: 186 RSLPSA 191
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,366,676,449
Number of Sequences: 518415
Number of Extensions: 41366676449
Number of Successful Extensions: 294470065
Number of sequences better than 0.0: 0
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