BLASTX 7.6.2
Query= UN10092 /QuerySize=1024
(1023 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9SZE4|VP322_ARATH Vacuolar protein sorting-associated protei... 372 3e-102
sp|O82197|VP321_ARATH Vacuolar protein sorting-associated protei... 327 7e-089
sp|Q5XGW6|CHM4B_XENLA Charged multivesicular body protein 4b OS=... 138 6e-032
sp|Q7ZVC4|CHM4B_DANRE Charged multivesicular body protein 4b OS=... 138 8e-032
sp|Q6GL11|CHM4B_XENTR Charged multivesicular body protein 4b OS=... 138 1e-031
sp|Q9BY43|CHM4A_HUMAN Charged multivesicular body protein 4a OS=... 136 4e-031
sp|Q9D8B3|CHM4B_MOUSE Charged multivesicular body protein 4b OS=... 135 7e-031
sp|Q86H98|CHMP4_DICDI Charged multivesicular body protein 4 OS=D... 135 7e-031
sp|Q9H444|CHM4B_HUMAN Charged multivesicular body protein 4b OS=... 134 9e-031
sp|Q9P7F7|SNF7_SCHPO Vacuolar-sorting protein snf7 OS=Schizosacc... 134 1e-030
sp|Q5ZHP5|CHM4B_CHICK Charged multivesicular body protein 4b OS=... 132 5e-030
sp|Q6IQ73|CHM4C_DANRE Charged multivesicular body protein 4c OS=... 131 8e-030
sp|A2VDY3|CHM4A_BOVIN Charged multivesicular body protein 4a OS=... 128 9e-029
sp|Q6GNN8|CHM4C_XENLA Charged multivesicular body protein 4c OS=... 121 8e-027
sp|Q6CJL0|SNF7_KLULA Vacuolar-sorting protein SNF7 OS=Kluyveromy... 118 9e-026
sp|Q96CF2|CHM4C_HUMAN Charged multivesicular body protein 4c OS=... 113 3e-024
sp|Q9D7F7|CHM4C_MOUSE Charged multivesicular body protein 4c OS=... 108 9e-023
sp|Q569C1|CHM4C_RAT Charged multivesicular body protein 4c OS=Ra... 108 9e-023
sp|Q6BSH2|SNF7_DEBHA Vacuolar-sorting protein SNF7 OS=Debaryomyc... 107 1e-022
sp|Q753W3|SNF7_ASHGO Vacuolar-sorting protein SNF7 OS=Ashbya gos... 105 8e-022
>sp|Q9SZE4|VP322_ARATH Vacuolar protein sorting-associated protein 32 homolog 2
OS=Arabidopsis thaliana GN=VPS32.2 PE=2 SV=1
Length = 219
Score = 372 bits (953), Expect = 3e-102
Identities = 199/219 (90%), Positives = 203/219 (92%), Gaps = 4/219 (1%)
Frame = +3
Query: 153 MMNRLFGKPKVENNALQTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAAI 332
MMNRLFGKPK E NALQTLDKLNETLEMLEKKEKVLLKKAG EVEKAKEY+RAKNKRAAI
Sbjct: 1 MMNRLFGKPKQEANALQTLDKLNETLEMLEKKEKVLLKKAGAEVEKAKEYSRAKNKRAAI 60
Query: 333 QCLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNID 512
QCLKRKRLYE QVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNID
Sbjct: 61 QCLKRKRLYEGQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNID 120
Query: 513 DVDKTMDEINEQTENMKQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLLQPTTV 692
DVDKTMDEINEQTENMKQIQEAL+TP+GAAADFDEDEL AEL+ELE ELE QLLQP T
Sbjct: 121 DVDKTMDEINEQTENMKQIQEALATPMGAAADFDEDELAAELDELESEELESQLLQPATT 180
Query: 693 ---LPSVPVPAGRQAARPTP-KRTAEEEELAALQAEMAL 797
LPSVPVPAGRQ ARP P KRTAEEEELAALQAEMAL
Sbjct: 181 APPLPSVPVPAGRQPARPVPQKRTAEEEELAALQAEMAL 219
>sp|O82197|VP321_ARATH Vacuolar protein sorting-associated protein 32 homolog 1
OS=Arabidopsis thaliana GN=VPS32.1 PE=2 SV=1
Length = 213
Score = 327 bits (838), Expect = 7e-089
Identities = 180/213 (84%), Positives = 189/213 (88%), Gaps = 7/213 (3%)
Frame = +3
Query: 156 MNRLFGKPKVENNALQTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAAIQ 335
MNRLFGKPK E + LQTLDKLNETLEMLEKKE VLLKKA EVEKAKE++RAKNKRAAIQ
Sbjct: 3 MNRLFGKPKQETSTLQTLDKLNETLEMLEKKENVLLKKATGEVEKAKEFSRAKNKRAAIQ 62
Query: 336 CLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNIDD 515
CLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALR+GASAMKAMQKATNIDD
Sbjct: 63 CLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRTGASAMKAMQKATNIDD 122
Query: 516 VDKTMDEINEQTENMKQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLLQPTTVL 695
VDKTMDEINEQTENMKQIQEALS P G A DFDEDELEAEL+ELEGAELEEQLLQP
Sbjct: 123 VDKTMDEINEQTENMKQIQEALSAPFG-ANDFDEDELEAELDELEGAELEEQLLQPV--- 178
Query: 696 PSVPVPAGRQAAR-PTPKR-TAEEEELAALQAE 788
+ VP G + AR P K+ TAEE+ELAALQAE
Sbjct: 179 -PIHVPQGNKPARAPAQKQPTAEEDELAALQAE 210
>sp|Q5XGW6|CHM4B_XENLA Charged multivesicular body protein 4b OS=Xenopus laevis
GN=chmp4b PE=2 SV=1
Length = 222
Score = 138 bits (347), Expect = 6e-032
Identities = 87/213 (40%), Positives = 126/213 (59%), Gaps = 8/213 (3%)
Frame = +3
Query: 147 VTMMNRLF---GKPKVENNALQTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKN 317
++++ +LF GK + + + KL +T EML KK++ L KK QE+ AK++ KN
Sbjct: 1 MSLIGKLFGTGGKGAKGPSPQEAIQKLRDTEEMLAKKQEFLEKKIEQELVTAKKH-GTKN 59
Query: 318 KRAAIQCLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQK 497
KRAA+Q LKRK+ YE+Q+ Q+ I Q LE A TE + + A AMKA
Sbjct: 60 KRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHD 119
Query: 498 ATNIDDVDKTMDEINEQTENMKQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLL 677
+I+ VD+ M +I +Q E ++I +A+S P+G DFDEDEL AELEELE EL++ LL
Sbjct: 120 NMDIEKVDELMQDIADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEELDKNLL 179
Query: 678 Q---PTTVLPSVPVPAGRQAARPTPKRTAEEEE 767
+ P TV P VPA A+P K+ E+++
Sbjct: 180 EVQGPETV-PLPNVPAASLPAKPVKKKQEEDDD 211
>sp|Q7ZVC4|CHM4B_DANRE Charged multivesicular body protein 4b OS=Danio rerio
GN=chmp4b PE=2 SV=1
Length = 220
Score = 138 bits (346), Expect = 8e-032
Identities = 83/199 (41%), Positives = 116/199 (58%), Gaps = 1/199 (0%)
Frame = +3
Query: 171 GKPKVENNALQTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAAIQCLKRK 350
GK + + + +L ET EML KK++ L KK QE+ AK+ KNKRAA+Q LKRK
Sbjct: 12 GKGGKSASPQEAIQRLRETEEMLTKKQEFLEKKIEQELVTAKK-NGTKNKRAALQALKRK 70
Query: 351 RLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNIDDVDKTM 530
+ YE+Q+ Q+ I Q LE A TE + + A AMKA +ID VD+ M
Sbjct: 71 KRYEKQLAQIDGTLSTIEFQREALENAHTNTEVIKNMGYAAKAMKAAHDNMDIDKVDELM 130
Query: 531 DEINEQTENMKQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLLQPTTVLPSVPV 710
+I EQ E ++I +A+S P+G +FDEDEL AELEELE EL++ LL+ +P V
Sbjct: 131 QDIIEQQELAQEISDAISKPVGFGEEFDEDELLAELEELEQEELDKNLLEIGDNVPLPNV 190
Query: 711 PAGRQAARPTPKRTAEEEE 767
P+ +RP K+ E+E+
Sbjct: 191 PSTSLPSRPAKKKEEEDED 209
>sp|Q6GL11|CHM4B_XENTR Charged multivesicular body protein 4b OS=Xenopus
tropicalis GN=chmp4b PE=2 SV=1
Length = 222
Score = 138 bits (345), Expect = 1e-031
Identities = 87/213 (40%), Positives = 126/213 (59%), Gaps = 8/213 (3%)
Frame = +3
Query: 147 VTMMNRLF---GKPKVENNALQTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKN 317
++++ +LF GK + + + KL +T EML KK++ L KK QE+ AK++ KN
Sbjct: 1 MSLIGKLFGTGGKGAKGPSPQEAIQKLRDTEEMLTKKQEFLEKKIEQELVTAKKH-GTKN 59
Query: 318 KRAAIQCLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQK 497
KRAA+Q LKRK+ YE+Q+ Q+ I Q LE A TE + + A AMKA
Sbjct: 60 KRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHD 119
Query: 498 ATNIDDVDKTMDEINEQTENMKQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLL 677
+I+ VD+ M +I +Q E ++I +A+S P+G DFDEDEL AELEELE EL++ LL
Sbjct: 120 NMDIEKVDELMQDIADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEELDKNLL 179
Query: 678 Q---PTTVLPSVPVPAGRQAARPTPKRTAEEEE 767
+ P TV P VPA A+P K+ E+++
Sbjct: 180 EVQGPETV-PLPNVPAAVLPAKPVKKKQEEDDD 211
>sp|Q9BY43|CHM4A_HUMAN Charged multivesicular body protein 4a OS=Homo sapiens
GN=CHMP4A PE=1 SV=3
Length = 222
Score = 136 bits (340), Expect = 4e-031
Identities = 89/220 (40%), Positives = 124/220 (56%), Gaps = 18/220 (8%)
Frame = +3
Query: 156 MNRLFGKPKVENNAL--QTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAA 329
+ RLFGK K E + + KL ET ++L KK++ L +K QE++ AK+Y KNKRAA
Sbjct: 4 LGRLFGKGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKY-GTKNKRAA 62
Query: 330 IQCLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNI 509
+Q L+RK+ +EQQ+ Q + Q +E A E + + A +MK + +I
Sbjct: 63 LQALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDI 122
Query: 510 DDVDKTMDEINEQTENMKQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLL---- 677
D VD+ M +I EQ E +QI +A+S P+G D DEDEL ELEELE EL ++LL
Sbjct: 123 DKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGD 182
Query: 678 ---QPTTVLPSVP---VPAGRQAARPTPKRTAEEEELAAL 779
+P+ LPSVP +PAG P PK +EE L L
Sbjct: 183 KEEEPSVKLPSVPSTHLPAG-----PAPKVDEDEEALKQL 217
>sp|Q9D8B3|CHM4B_MOUSE Charged multivesicular body protein 4b OS=Mus musculus
GN=Chmp4b PE=2 SV=2
Length = 224
Score = 135 bits (338), Expect = 7e-031
Identities = 83/198 (41%), Positives = 120/198 (60%), Gaps = 7/198 (3%)
Frame = +3
Query: 201 QTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAAIQCLKRKRLYEQQVEQL 380
+ + +L +T EML KK++ L KK QE+ AK++ KNKRAA+Q LKRK+ YE+Q+ Q+
Sbjct: 24 EAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKH-GTKNKRAALQALKRKKRYEKQLAQI 82
Query: 381 GNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNIDDVDKTMDEINEQTENM 560
I Q LE A TE + + A AMKA +ID VD+ M +I +Q E
Sbjct: 83 DGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIADQQELA 142
Query: 561 KQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLLQ---PTTV-LPSVPVPAGRQA 728
++I A+S P+G +FDEDEL AELEELE EL++ LL+ P TV LP+VP A
Sbjct: 143 EEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPSVA--LP 200
Query: 729 ARPTPKRTAEEEELAALQ 782
++P K+ E++++ L+
Sbjct: 201 SKPAKKKEEEDDDMKELE 218
>sp|Q86H98|CHMP4_DICDI Charged multivesicular body protein 4 OS=Dictyostelium
discoideum GN=chmp4 PE=3 SV=1
Length = 215
Score = 135 bits (338), Expect = 7e-031
Identities = 82/217 (37%), Positives = 124/217 (57%), Gaps = 8/217 (3%)
Frame = +3
Query: 162 RLFGKPKVENNALQTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAAIQCL 341
+LFGKPK + + +T+ KL TL+MLEK++ L K +E EKAK K KR A+ CL
Sbjct: 2 KLFGKPKPKQDTQETIGKLRLTLDMLEKRQTFLQDKLEKEQEKAKVLVSQKRKREALLCL 61
Query: 342 KRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNIDDVD 521
K++ ++ +V +L ++ Q+ LE AK E ++++R GA +++ + ID VD
Sbjct: 62 KKRNNFQNEVTKLQGSYDTLNQQIFALENAKMNMEIMNSMRDGARSLRELHGHLTIDKVD 121
Query: 522 KTMDEINEQTENMKQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLLQPTTVLPS 701
++EI EQ E ++I A+S P+G + DE+EL EL E E EL+ QLL PS
Sbjct: 122 DVIEEIQEQMEIHEEISNAISQPLGNQVE-DEEELLRELAEYEQEELDAQLL--NIKAPS 178
Query: 702 VPVPAGRQAARPT-----PKRTAEEEELAALQAEMAL 797
+P Q PT PK + EEEE+ AL+ +A+
Sbjct: 179 RELPQEIQVNFPTISKTVPKLSKEEEEIRALEESLAM 215
>sp|Q9H444|CHM4B_HUMAN Charged multivesicular body protein 4b OS=Homo sapiens
GN=CHMP4B PE=1 SV=1
Length = 224
Score = 134 bits (337), Expect = 9e-031
Identities = 83/198 (41%), Positives = 120/198 (60%), Gaps = 7/198 (3%)
Frame = +3
Query: 201 QTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAAIQCLKRKRLYEQQVEQL 380
+ + +L +T EML KK++ L KK QE+ AK++ KNKRAA+Q LKRK+ YE+Q+ Q+
Sbjct: 24 EAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKH-GTKNKRAALQALKRKKRYEKQLAQI 82
Query: 381 GNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNIDDVDKTMDEINEQTENM 560
I Q LE A TE + + A AMKA +ID VD+ M +I +Q E
Sbjct: 83 DGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIADQQELA 142
Query: 561 KQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLLQ---PTTV-LPSVPVPAGRQA 728
++I A+S P+G +FDEDEL AELEELE EL++ LL+ P TV LP+VP A
Sbjct: 143 EEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPSIA--LP 200
Query: 729 ARPTPKRTAEEEELAALQ 782
++P K+ E++++ L+
Sbjct: 201 SKPAKKKEEEDDDMKELE 218
>sp|Q9P7F7|SNF7_SCHPO Vacuolar-sorting protein snf7 OS=Schizosaccharomyces pombe
GN=snf7 PE=2 SV=1
Length = 222
Score = 134 bits (336), Expect = 1e-030
Identities = 76/218 (34%), Positives = 127/218 (58%), Gaps = 7/218 (3%)
Frame = +3
Query: 162 RLFGKPKVENNALQTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAAIQCL 341
R FG + ++ T+ + E L + +KKE+VL ++ ++ E A++ NKR A+ L
Sbjct: 6 RWFGGNRSKDTTKDTIVRFQEMLALYDKKEEVLERQIAEQTEIARK-NATTNKRLALTAL 64
Query: 342 KRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNIDDVD 521
KRK+++E ++ ++ + I Q+ ++ A ET+ A+R GA AMK++Q+ + D VD
Sbjct: 65 KRKKMHENELVKIEGSRNNIEQQLFSIQNANLNFETLQAMRQGAEAMKSIQRGMDADKVD 124
Query: 522 KTMDEINEQTENMKQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLL---QPTTV 692
+ MD+I +Q ++I +STP+G A+ DEDEL EL+EL+ EL+ ++L +P
Sbjct: 125 QIMDKIRDQQTISEEISTMISTPVGLNAEIDEDELANELDELQQMELDSKMLGAEKPPVH 184
Query: 693 LPSVPVPAGRQAARPT---PKRTAEEEELAALQAEMAL 797
P+VP + P+ P+ EEEEL LQAE +L
Sbjct: 185 TPAVPAVPSQVKDLPSISKPQELDEEEELRKLQAEFSL 222
>sp|Q5ZHP5|CHM4B_CHICK Charged multivesicular body protein 4b OS=Gallus gallus
GN=CHMP4B PE=2 SV=1
Length = 227
Score = 132 bits (331), Expect = 5e-030
Identities = 81/196 (41%), Positives = 116/196 (59%), Gaps = 13/196 (6%)
Frame = +3
Query: 201 QTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAAIQCLKRKRLYEQQVEQL 380
+ + +L +T EML KK++ L KK QE+ A+++ KNKRAA+Q LKRK+ YE+Q+ Q+
Sbjct: 26 EAIQRLRDTEEMLSKKQEFLEKKIEQELAAARKH-GTKNKRAALQALKRKKRYEKQLAQI 84
Query: 381 GNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNIDDVDKTMDEINEQTENM 560
I Q LE A TE + + A AMKA +ID VD+ M +I EQ E
Sbjct: 85 DGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIDKVDELMQDIAEQQELA 144
Query: 561 KQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLLQ---PTTV----LPSVPVPAG 719
+I A+S P+G +FDEDEL AELEELE EL++ LL+ P TV +PS+ +P
Sbjct: 145 DEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPSISIP-- 202
Query: 720 RQAARPTPKRTAEEEE 767
++P K+ EE++
Sbjct: 203 ---SKPAKKKEEEEDD 215
>sp|Q6IQ73|CHM4C_DANRE Charged multivesicular body protein 4c OS=Danio rerio
GN=chmp4c PE=2 SV=1
Length = 224
Score = 131 bits (329), Expect = 8e-030
Identities = 85/194 (43%), Positives = 113/194 (58%), Gaps = 6/194 (3%)
Frame = +3
Query: 201 QTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAAIQCLKRKRLYEQQVEQL 380
+ + KL ET EML KK+ L KK E+ AK+ KNKRAA+Q LKRK+ YE+Q+ Q+
Sbjct: 22 EAIQKLRETEEMLAKKQDFLEKKIDAELLIAKK-NGTKNKRAALQALKRKKRYEKQLAQI 80
Query: 381 GNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNIDDVDKTMDEINEQTENM 560
I Q LE A TE + + A AMK + +ID VD M +I EQ E
Sbjct: 81 DGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKTAHENMDIDKVDDLMQDITEQQELA 140
Query: 561 KQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLLQ---PTTV-LPSVPV-PAGRQ 725
++I +A+S P+G +FDEDEL AELEELE EL++ LLQ P V LP+VP P ++
Sbjct: 141 QEISDAISRPVGFGEEFDEDELMAELEELEQEELDKDLLQISGPEDVPLPNVPSNPLPKK 200
Query: 726 AARPTPKRTAEEEE 767
A KR E+E+
Sbjct: 201 TAVAQKKRQEEDED 214
>sp|A2VDY3|CHM4A_BOVIN Charged multivesicular body protein 4a OS=Bos taurus
GN=CHMP4A PE=2 SV=1
Length = 222
Score = 128 bits (320), Expect = 9e-029
Identities = 83/217 (38%), Positives = 117/217 (53%), Gaps = 12/217 (5%)
Frame = +3
Query: 156 MNRLFGKPKVENNAL--QTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAA 329
+ RLFG+ K E + + KL ET ++L KK++ L +K QE++ AK++ KNKRAA
Sbjct: 4 LGRLFGRGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIEQELQAAKKH-GTKNKRAA 62
Query: 330 IQCLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNI 509
+Q L+RK+ EQQ+ Q + Q +E A E + + A +K + +I
Sbjct: 63 LQALRRKKRLEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQGLKKAYQDMDI 122
Query: 510 DDVDKTMDEINEQTENMKQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLL---- 677
D VD+ M +I EQ E +QI +A+S P+G D DEDEL ELEELE EL +LL
Sbjct: 123 DKVDELMADITEQQEVAQQISDAISRPVGFGDDVDEDELLEELEELEQEELARELLHVGD 182
Query: 678 ---QPTTVLPSVPVPAGRQAARPTPKRTAEEEELAAL 779
+P LPS P+ A P PK +E EL L
Sbjct: 183 EEEEPPVALPS--APSTHLPAEPAPKADEDEAELKQL 217
>sp|Q6GNN8|CHM4C_XENLA Charged multivesicular body protein 4c OS=Xenopus laevis
GN=chmp4c PE=2 SV=1
Length = 227
Score = 121 bits (303), Expect = 8e-027
Identities = 75/195 (38%), Positives = 113/195 (57%), Gaps = 6/195 (3%)
Frame = +3
Query: 192 NALQTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAAIQCLKRKRLYEQQV 371
+A + L KL ET EML KK++ L KK E+ AK++ KNKRAA+Q LK+K+ E+Q+
Sbjct: 25 SAQEALFKLRETEEMLTKKQEYLEKKIELELATAKKH-GTKNKRAALQALKKKKRLEKQL 83
Query: 372 EQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNIDDVDKTMDEINEQT 551
Q+ I Q LE + TE + + A AMKA + +++ +D M +I+EQ
Sbjct: 84 AQIDGTLSTIEFQREALENSHTNTEVLKNMGYAAKAMKAAHENMDLEKIDDLMQDIHEQQ 143
Query: 552 ENMKQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLLQPTTVLPSVP---VPAGR 722
+ ++I +A+S P+G +FDEDEL ELEELE +L Q+ LPSVP +P+ +
Sbjct: 144 DVAQEISDAISRPVGFGDEFDEDELLEELEELEQEDLNSQMANVN--LPSVPSSKLPSTK 201
Query: 723 QAARPTPKRTAEEEE 767
+RP R E++
Sbjct: 202 LPSRPASSRKKVEDD 216
>sp|Q6CJL0|SNF7_KLULA Vacuolar-sorting protein SNF7 OS=Kluyveromyces lactis
GN=SNF7 PE=3 SV=1
Length = 232
Score = 118 bits (294), Expect = 9e-026
Identities = 72/195 (36%), Positives = 110/195 (56%), Gaps = 10/195 (5%)
Frame = +3
Query: 153 MMNRLFGKPKVENN-ALQTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAA 329
M FG K + + + L E +++L KK+ L + Q+ + AK+ ++ NK A
Sbjct: 1 MWGYFFGTSKQQKELPKKAIVDLREHIQLLNKKQAHLQTQIDQQQQLAKKSLQSGNKNNA 60
Query: 330 IQCLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNI 509
LK+K+LYE Q+++L + + Q+ +E A ET+ A++ GASAMK + K ++
Sbjct: 61 KTYLKKKKLYESQLDKLQSQIDSLDQQLYSIENANLNLETLKAMKQGASAMKNIHKGLDL 120
Query: 510 DDVDKTMDEINEQTENMKQIQEALSTPIGAAADFDEDELEAELEELEGAEL--------- 662
D VD TMDEI EQ E ++I EA+S P+ + DEDEL+ ELE LE L
Sbjct: 121 DKVDDTMDEIREQVELNQEISEAISKPLILQDELDEDELDQELELLESENLQKEHIAPVP 180
Query: 663 EEQLLQPTTVLPSVP 707
++Q+ QP+ LPSVP
Sbjct: 181 QQQIQQPSIDLPSVP 195
>sp|Q96CF2|CHM4C_HUMAN Charged multivesicular body protein 4c OS=Homo sapiens
GN=CHMP4C PE=1 SV=1
Length = 233
Score = 113 bits (281), Expect = 3e-024
Identities = 75/206 (36%), Positives = 115/206 (55%), Gaps = 7/206 (3%)
Frame = +3
Query: 174 KPKVENNALQTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAAIQCLKRKR 353
K + + + L +L ET EML KK++ L + +E+ AK++ +NKRAA+Q LKRK+
Sbjct: 15 KSRAAPSPQEALVRLRETEEMLGKKQEYLENRIQREIALAKKH-GTQNKRAALQALKRKK 73
Query: 354 LYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNIDDVDKTMD 533
+E+Q+ Q+ I Q LE + TE + + A AMK++ + +++ +D M
Sbjct: 74 RFEKQLTQIDGTLSTIEFQREALENSHTNTEVLRNMGFAAKAMKSVHENMDLNKIDDLMQ 133
Query: 534 EINEQTENMKQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLLQPTTVLPSVP-- 707
EI EQ + ++I EA S +G DFDEDEL AELEELE EL +++ LP+VP
Sbjct: 134 EITEQQDIAQEISEAFSQRVGFGDDFDEDELMAELEELEQEELNKKM--TNIRLPNVPSS 191
Query: 708 -VPAGRQAARPTPKRTAEEEELAALQ 782
+PA + +P TA A+ Q
Sbjct: 192 SLPA-QPNRKPGMSSTARRSRAASSQ 216
>sp|Q9D7F7|CHM4C_MOUSE Charged multivesicular body protein 4c OS=Mus musculus
GN=Chmp4c PE=2 SV=1
Length = 232
Score = 108 bits (268), Expect = 9e-023
Identities = 68/186 (36%), Positives = 106/186 (56%), Gaps = 4/186 (2%)
Frame = +3
Query: 192 NALQTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAAIQCLKRKRLYEQQV 371
+A + L +L ET EML KK++ L + +E+ AK++ ++NKRAA+Q LKRK+ +E+Q+
Sbjct: 21 SAQEALARLRETEEMLAKKQEYLENRIQRELALAKKH-GSQNKRAALQALKRKKRFEKQL 79
Query: 372 EQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNIDDVDKTMDEINEQT 551
Q+ I Q LE + TE + + A AMKA+ +++ +D M +I EQ
Sbjct: 80 TQVDGTLSTIEFQREALENSHTNTEVLRNMGFAAKAMKAVHDNMDLNKIDDLMQDITEQQ 139
Query: 552 ENMKQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLLQ---PTTVLPSVPVPAGR 722
+ ++I EA S + A FDE EL AELEELE EL +++ P S+P R
Sbjct: 140 DIAQEISEAFSQRVQFADGFDEAELLAELEELEQEELNKKMTSLELPNVPSSSLPAQPSR 199
Query: 723 QAARPT 740
+A+ P+
Sbjct: 200 KASMPS 205
>sp|Q569C1|CHM4C_RAT Charged multivesicular body protein 4c OS=Rattus norvegicus
GN=Chmp4c PE=2 SV=1
Length = 232
Score = 108 bits (268), Expect = 9e-023
Identities = 67/186 (36%), Positives = 106/186 (56%), Gaps = 4/186 (2%)
Frame = +3
Query: 192 NALQTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAAIQCLKRKRLYEQQV 371
+A + L +L E EM+ KK++ L + +E+ AK++ ++NKRAA+Q LKRK+ +E+Q+
Sbjct: 21 SAQEALARLREIEEMMAKKQEYLENRIQRELALAKKH-GSQNKRAALQALKRKKRFEKQL 79
Query: 372 EQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNIDDVDKTMDEINEQT 551
Q+ I Q LE + TE + + A AMKA+ + +++ +D M +I EQ
Sbjct: 80 TQIDGTLSTIEFQREALENSHTNTEVLRNMGFAAKAMKAVHENMDLNKIDDLMQDITEQQ 139
Query: 552 ENMKQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLLQ---PTTVLPSVPVPAGR 722
+ ++I EA S + A FDEDEL AELEELE EL +++ P S+P R
Sbjct: 140 DIAQEISEAFSQRVQFADGFDEDELLAELEELEQEELNKKMTSMELPNVPSSSLPAQPSR 199
Query: 723 QAARPT 740
+A P+
Sbjct: 200 KAGVPS 205
>sp|Q6BSH2|SNF7_DEBHA Vacuolar-sorting protein SNF7 OS=Debaryomyces hansenii
GN=SNF7 PE=3 SV=2
Length = 226
Score = 107 bits (267), Expect = 1e-022
Identities = 77/228 (33%), Positives = 112/228 (49%), Gaps = 15/228 (6%)
Frame = +3
Query: 153 MMNRLFG--KPKVENNALQTLDKLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRA 326
M N LFG K + + + + +L E ++ML KK L + + A++Y NK
Sbjct: 1 MWNYLFGGNKQQKKEYPKKAIVELREHIQMLNKKRSHLESQIADQDALARKYI-TTNKAL 59
Query: 327 AIQCLKRKRLYEQQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATN 506
A LKRK+ YE + ++ N + Q+ +EGA ET+ A++ GA AMK + +
Sbjct: 60 AKNALKRKKGYEANLMKIENQIDSLETQLTSIEGANLNLETMKAMKQGAQAMKQIHGEYD 119
Query: 507 IDDVDKTMDEINEQTENMKQIQEALSTPIGAAADFDEDELEAELEELEGAELEEQLLQPT 686
+D V+ TMD+I EQ E +I EA+S P+G DEDEL+ EL L+ E E + P
Sbjct: 120 VDKVENTMDDIREQVELADEISEAISRPVGTEF-VDEDELDEELAMLQEEEKEHKQQTPA 178
Query: 687 TVLPSVPVPAGRQAARPTP-----------KRTAEEEELAALQAEMAL 797
P V A + P + +EE L ALQAEM L
Sbjct: 179 QKAPVAKVSAPEEEMPDFPTVNKNKPAASTEDDEDEEALKALQAEMGL 226
>sp|Q753W3|SNF7_ASHGO Vacuolar-sorting protein SNF7 OS=Ashbya gossypii GN=SNF7
PE=3 SV=1
Length = 237
Score = 105 bits (260), Expect = 8e-022
Identities = 58/186 (31%), Positives = 104/186 (55%), Gaps = 2/186 (1%)
Frame = +3
Query: 213 KLNETLEMLEKKEKVLLKKAGQEVEKAKEYTRAKNKRAAIQCLKRKRLYEQQVEQLGNFQ 392
+L E +++L KK+ L + + E A+ + NK A LKRK+++E Q+ ++
Sbjct: 24 ELREHIQLLSKKQAHLQTQMTSQEESARHFLSKGNKNMAKAALKRKKVFESQLLKIDKQV 83
Query: 393 LRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNIDDVDKTMDEINEQTENMKQIQ 572
+ Q+ +E A ET+ A++ GASAMK + + +++ VD+TMDEI EQ E ++I
Sbjct: 84 DSLEQQLYSIENANLNLETMKAMKQGASAMKHIHEGLDVERVDETMDEIREQVELGEEIS 143
Query: 573 EALSTPIGAAA-DFDEDELEAELEELEGAELEEQLLQPTTVLPSVPVPAGRQAARPTPKR 749
EA+S P+ + DEDEL+ EL+ L E+ ++++P +P+ PA + + P
Sbjct: 144 EAISRPLYTGVNEIDEDELDEELDMLAQEEVARKVMEPGAAVPAA-APATKVSLPSVPSS 202
Query: 750 TAEEEE 767
+++
Sbjct: 203 DMPQQD 208
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,366,676,449
Number of Sequences: 518415
Number of Extensions: 41366676449
Number of Successful Extensions: 294470065
Number of sequences better than 0.0: 0
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