BLASTX 7.6.2
Query= UN10237 /QuerySize=1274
(1273 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q41969|IF2B_ARATH Eukaryotic translation initiation factor 2 ... 453 1e-126
sp|P55871|IF2B_MALDO Eukaryotic translation initiation factor 2 ... 399 2e-110
sp|O24473|IF2B_WHEAT Eukaryotic translation initiation factor 2 ... 379 3e-104
sp|Q99L45|IF2B_MOUSE Eukaryotic translation initiation factor 2 ... 243 2e-063
sp|P41375|IF2B_DROME Eukaryotic translation initiation factor 2 ... 242 4e-063
sp|Q5E9D0|IF2B_BOVIN Eukaryotic translation initiation factor 2 ... 242 6e-063
sp|P41035|IF2B_RABIT Eukaryotic translation initiation factor 2 ... 242 6e-063
sp|P20042|IF2B_HUMAN Eukaryotic translation initiation factor 2 ... 240 2e-062
sp|Q5R4T9|IF2B_PONAB Eukaryotic translation initiation factor 2 ... 238 6e-062
sp|P56329|IF2B_SCHPO Probable eukaryotic translation initiation ... 231 1e-059
sp|A6NK07|IF2BL_HUMAN Eukaryotic translation initiation factor 2... 219 4e-056
sp|Q54T27|IF2B_DICDI Eukaryotic translation initiation factor 2 ... 213 3e-054
sp|P09064|IF2B_YEAST Eukaryotic translation initiation factor 2 ... 186 3e-046
sp|Q21230|IF2B_CAEEL Eukaryotic translation initiation factor 2 ... 180 2e-044
sp|C5A2A8|IF2B_THEGJ Translation initiation factor 2 subunit bet... 103 3e-021
sp|O58312|IF2B_PYRHO Translation initiation factor 2 subunit bet... 102 9e-021
sp|Q9UYR6|IF2B_PYRAB Translation initiation factor 2 subunit bet... 101 2e-020
sp|A2SSW2|IF2B_METLZ Translation initiation factor 2 subunit bet... 100 3e-020
sp|Q8U3I5|IF2B_PYRFU Translation initiation factor 2 subunit bet... 99 4e-020
>sp|Q41969|IF2B_ARATH Eukaryotic translation initiation factor 2 subunit beta
OS=Arabidopsis thaliana GN=EMB1401 PE=2 SV=3
Length = 268
Score = 453 bits (1165), Expect = 1e-126
Identities = 228/269 (84%), Positives = 243/269 (90%), Gaps = 6/269 (2%)
Frame = +3
Query: 210 IKEVKDEQD-LAPFDPTKKKKKKKVVIQDPIEDCTESSQPEKSDSLPANDGLESSFAGLK 386
I E+++EQ+ LAPFDP+KKKKKKKVVIQ+P+ED ESSQ EKSDSLP NDGLESSF G+K
Sbjct: 5 INEIREEQEQLAPFDPSKKKKKKKVVIQEPVEDLAESSQTEKSDSLPVNDGLESSFTGMK 64
Query: 387 KKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQQRYPWEGSDRDYIYD 566
KKKKKP E SS LN ES+D EDLDE AND++E EGI L QQRYPWEGS+RDYIYD
Sbjct: 65 KKKKKPTE-SSLLNNESVDAGEDLDEIANDEQEGEEGIVL----QQRYPWEGSERDYIYD 119
Query: 567 ELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMN 746
ELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVM
Sbjct: 120 ELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMQ 179
Query: 747 FLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLF 926
+LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRY+T+YVICLGCKSPDTILSKENRLF
Sbjct: 180 YLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYITDYVICLGCKSPDTILSKENRLF 239
Query: 927 FLRCEKCGSGRSVAQIKAGFVARVGRRKT 1013
FLRCEKCGS RSVA IK GFVARV RRKT
Sbjct: 240 FLRCEKCGSQRSVAPIKTGFVARVSRRKT 268
Score = 448 bits (1152), Expect = 4e-125
Identities = 226/268 (84%), Positives = 241/268 (89%), Gaps = 7/268 (2%)
Frame = +3
Query: 195 DENNEIKEVKDEQDLAPFDPTKKKKKKKVVIQDPIEDCTESSQPEKSDSLPANDGLESSF 374
DE NEI+E +++ LAPFDP+KKKKKKKVVIQ+P+ED ESSQ EKSDSLP NDGLESSF
Sbjct: 3 DEINEIRE--EQEQLAPFDPSKKKKKKKVVIQEPVEDLAESSQTEKSDSLPVNDGLESSF 60
Query: 375 AGLKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQQRYPWEGSDRD 554
G+KKKKKKP E SS LN ES+D EDLDE AND++E EGI L QQRYPWEGS+RD
Sbjct: 61 TGMKKKKKKPTE-SSLLNNESVDAGEDLDEIANDEQEGEEGIVL----QQRYPWEGSERD 115
Query: 555 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 734
YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD
Sbjct: 116 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 175
Query: 735 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 914
HVM +LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRY+T+YVICLGCKSPDTILSKE
Sbjct: 176 HVMQYLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYITDYVICLGCKSPDTILSKE 235
Query: 915 NRLFFLRCEKCGSGRSVAQIKAGFVARV 998
NRLFFLRCEKCGS RSVA IK GFVARV
Sbjct: 236 NRLFFLRCEKCGSQRSVAPIKTGFVARV 263
>sp|P55871|IF2B_MALDO Eukaryotic translation initiation factor 2 subunit beta
OS=Malus domestica PE=2 SV=2
Length = 271
Score = 399 bits (1025), Expect = 2e-110
Identities = 208/266 (78%), Positives = 227/266 (85%), Gaps = 8/266 (3%)
Frame = +3
Query: 216 EVKDE--QDLAPFDPTKKKKKKKVVIQDPIEDCTESSQPEKSDSLPANDGLESSFAGLKK 389
EVKDE D+APFDPTKKKKKK+VVIQD +D + EK+++ A++G ES+FAGLKK
Sbjct: 8 EVKDEVVADIAPFDPTKKKKKKEVVIQDTTDD-SVGKLAEKAEACTASEGQESTFAGLKK 66
Query: 390 KKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQQRYPWEGSDRDYIYDE 569
KKKKP+E +S LNEES D EDL+E +DEE EGI L+ YPWEGSDRDY Y+E
Sbjct: 67 KKKKPIE-TSILNEESGDAVEDLNERTGEDEE-GEGIVLETPS---YPWEGSDRDYTYEE 121
Query: 570 LLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNF 749
LL RVF ILRENNP+LAGDRRRTVMRPPQVLREGTKK VFVNFMDLCKTMHRQPDHVM F
Sbjct: 122 LLDRVFTILRENNPDLAGDRRRTVMRPPQVLREGTKKAVFVNFMDLCKTMHRQPDHVMAF 181
Query: 750 LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFF 929
LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYV EYVICLGC+SPDTILSKENRLFF
Sbjct: 182 LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVNEYVICLGCQSPDTILSKENRLFF 241
Query: 930 LRCEKCGSGRSVAQIKAGFVARVGRR 1007
LRCEKCGSGRSVA KAGF+ARVGRR
Sbjct: 242 LRCEKCGSGRSVAPNKAGFMARVGRR 267
>sp|O24473|IF2B_WHEAT Eukaryotic translation initiation factor 2 subunit beta
OS=Triticum aestivum PE=1 SV=1
Length = 270
Score = 379 bits (972), Expect = 3e-104
Identities = 194/263 (73%), Positives = 219/263 (83%), Gaps = 6/263 (2%)
Frame = +3
Query: 222 KDEQDLAPFDPTKKKKKKKVVIQDPIEDCTESSQPEKSDSLPANDGLESSFAGLKKKKKK 401
++ ++APFDPTKKKKKKKVVIQDP ++ + + EK++ L + E+SF GLKKKKKK
Sbjct: 11 EEATEIAPFDPTKKKKKKKVVIQDPADEVDKLA--EKTEGLSVTESGEASFVGLKKKKKK 68
Query: 402 PVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQQRYPWEGSDRDYIYDELLGR 581
VE+ SL E D + LD+ +DE+ EGI L Q YPWEG+DRDY YDELLGR
Sbjct: 69 LVELDPSLVEAG-DGEDTLDDQVGEDEQ-GEGIVLGGATQ--YPWEGTDRDYKYDELLGR 124
Query: 582 VFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAE 761
VFNILRENNP+LAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQP+HVM FLLAE
Sbjct: 125 VFNILRENNPDLAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPEHVMMFLLAE 184
Query: 762 LGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFFLRCE 941
+GTSGSLDGQQRLV+KGRFAPKNFE ILRRY+ EYVIC GCKSPDTILSKENRLFFLRCE
Sbjct: 185 MGTSGSLDGQQRLVIKGRFAPKNFEAILRRYINEYVICHGCKSPDTILSKENRLFFLRCE 244
Query: 942 KCGSGRSVAQIKAGFVARVGRRK 1010
+CGS RSVA IKAGFVA+VGRRK
Sbjct: 245 QCGSSRSVAPIKAGFVAQVGRRK 267
>sp|Q99L45|IF2B_MOUSE Eukaryotic translation initiation factor 2 subunit 2
OS=Mus musculus GN=Eif2s2 PE=1 SV=1
Length = 331
Score = 243 bits (620), Expect = 2e-063
Identities = 137/276 (49%), Positives = 180/276 (65%), Gaps = 15/276 (5%)
Frame = +3
Query: 195 DENNEIKEVKDE-QDLAPFDPTKKKKK-KKVVIQDPIEDCTESSQPEKSDSLPA--NDGL 362
+E++ K+ D+ DL F+ KKKKK KK+ D E+ + + E PA D L
Sbjct: 58 EEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEAIKDVKIESDAQEPAEPEDDL 117
Query: 363 ESSFAGLKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQQRYPWEG 542
+ G KKKKKK V+ +E L+ E L++ +D + +GI Q W G
Sbjct: 118 D-IMLGNKKKKKKNVKFPE--EDEILEKDEALED---EDSKKDDGISFSSQT----AWAG 167
Query: 543 SDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTM 719
S+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +
Sbjct: 168 SERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLL 227
Query: 720 HRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDT 899
HRQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPDT
Sbjct: 228 HRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDT 287
Query: 900 ILSKENRLFFLRCEKCGSGRSVAQIKAGFVARVGRR 1007
IL K+ RL+FL+CE C S SVA IK GF A G+R
Sbjct: 288 ILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 323
>sp|P41375|IF2B_DROME Eukaryotic translation initiation factor 2 subunit 2
OS=Drosophila melanogaster GN=eIF-2beta PE=1 SV=1
Length = 312
Score = 242 bits (617), Expect = 4e-063
Identities = 134/272 (49%), Positives = 169/272 (62%), Gaps = 30/272 (11%)
Frame = +3
Query: 222 KDEQDLAPFDPTKKKKKKKVVIQDPIE---------DCTESSQPEKSDSLPANDGLESSF 374
+D DL F KKKKKKK D IE D S +PE+ + N ++ S
Sbjct: 53 EDNLDLESFG-KKKKKKKKPFNMDEIEAAIPSFGGDDVAASEEPEEEE---INLDMDFSM 108
Query: 375 AGLKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQQRYPWEGSDRD 554
A KKK KK ++LDE D +D + D + + W GSDRD
Sbjct: 109 AKKKKKSKK----------------KELDELFADQADDDKSEDKENDEDNSSTWFGSDRD 152
Query: 555 YIYDELLGRVFNILRENNPELAGDRR-RTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQP 731
Y YDELL RVF I+ + NP++A R+ + VMRPPQVLR GTKKT F NFMD+ KT+HR P
Sbjct: 153 YTYDELLKRVFEIILDKNPDMAAGRKPKFVMRPPQVLRVGTKKTSFANFMDIAKTLHRLP 212
Query: 732 DHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSK 911
H+++FLLAELGTSGS+DG Q+L++KGRF PK E +LRRY+ EYV C C+SP+TIL K
Sbjct: 213 KHLLDFLLAELGTSGSMDGNQQLIIKGRFQPKQIENVLRRYIKEYVTCHTCRSPETILQK 272
Query: 912 ENRLFFLRCEKCGSGRSVAQIKAGFVARVGRR 1007
+ RLFFL+CE CGS SVA IK+GF A G+R
Sbjct: 273 DTRLFFLQCESCGSRCSVASIKSGFQAVTGKR 304
>sp|Q5E9D0|IF2B_BOVIN Eukaryotic translation initiation factor 2 subunit 2
OS=Bos taurus GN=EIF2S2 PE=2 SV=1
Length = 333
Score = 242 bits (616), Expect = 6e-063
Identities = 136/275 (49%), Positives = 178/275 (64%), Gaps = 11/275 (4%)
Frame = +3
Query: 195 DENNEIKEVKDE-QDLAPFDPTKKKKK-KKVVIQDPIEDCTESSQPEKSDSLPANDGLE- 365
+E++ K+ D+ DL F+ KKKKK KK+ D E+ + + E PA +
Sbjct: 58 EEDSRKKDASDDLDDLNFFNQKKKKKKSKKIFDIDEAEEGIKDLKIESDVQEPAEPEEDL 117
Query: 366 SSFAGLKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQQRYPWEGS 545
G KKKKKK V+ +E L+ E L++ +D + +GI Q W GS
Sbjct: 118 DIMLGNKKKKKKVVKFPD--EDEVLEKDEALED---EDSKKDDGISFSNQTGP--AWAGS 170
Query: 546 DRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMH 722
+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +H
Sbjct: 171 ERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLH 230
Query: 723 RQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTI 902
RQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPDTI
Sbjct: 231 RQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTI 290
Query: 903 LSKENRLFFLRCEKCGSGRSVAQIKAGFVARVGRR 1007
L K+ RL+FL+CE C S SVA IK GF A GRR
Sbjct: 291 LQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGRR 325
>sp|P41035|IF2B_RABIT Eukaryotic translation initiation factor 2 subunit 2
OS=Oryctolagus cuniculus GN=EIF2S2 PE=1 SV=1
Length = 333
Score = 242 bits (616), Expect = 6e-063
Identities = 137/276 (49%), Positives = 180/276 (65%), Gaps = 13/276 (4%)
Frame = +3
Query: 195 DENNEIKEVKDE-QDLAPFDPTKKKKK-KKVVIQDPIEDCTESSQPEKSDSLPA--NDGL 362
+E++ K+ D+ DL F+ KKKKK KK+ D E+ + + E PA D L
Sbjct: 58 EEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIENDVQEPAEPEDDL 117
Query: 363 ESSFAGLKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQQRYPWEG 542
+ G KKKKKK V+ +E L+ E L++ +D + +GI Q W G
Sbjct: 118 D-IMLGNKKKKKKNVKFPD--EDEILEKDEALED---EDSKKDDGISFSNQTGP--AWAG 169
Query: 543 SDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTM 719
S+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +
Sbjct: 170 SERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLL 229
Query: 720 HRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDT 899
HRQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPDT
Sbjct: 230 HRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDT 289
Query: 900 ILSKENRLFFLRCEKCGSGRSVAQIKAGFVARVGRR 1007
IL K+ RL+FL+CE C S SVA IK GF A G+R
Sbjct: 290 ILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 325
>sp|P20042|IF2B_HUMAN Eukaryotic translation initiation factor 2 subunit 2
OS=Homo sapiens GN=EIF2S2 PE=1 SV=2
Length = 333
Score = 240 bits (611), Expect = 2e-062
Identities = 136/277 (49%), Positives = 177/277 (63%), Gaps = 15/277 (5%)
Frame = +3
Query: 195 DENNEIKEVKDEQDLAPFDPTKKKKKKKVVIQDPIEDCTESSQPEKSDS-----LPANDG 359
+E+ K+ D+ D F KKKKKK I D I++ E + K +S D
Sbjct: 58 EEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFD-IDEAEEGVKDLKIESDVQEPTEPEDD 116
Query: 360 LESSFAGLKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQQRYPWE 539
L+ G KKKKKK V+ +E L+ E L++ +D + +GI Q W
Sbjct: 117 LD-IMLGNKKKKKKNVKFPD--EDEILEKDEALED---EDNKKDDGISFSNQTGP--AWA 168
Query: 540 GSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKT 716
GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK
Sbjct: 169 GSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKL 228
Query: 717 MHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPD 896
+HRQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPD
Sbjct: 229 LHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPD 288
Query: 897 TILSKENRLFFLRCEKCGSGRSVAQIKAGFVARVGRR 1007
TIL K+ RL+FL+CE C S SVA IK GF A G+R
Sbjct: 289 TILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 325
>sp|Q5R4T9|IF2B_PONAB Eukaryotic translation initiation factor 2 subunit 2
OS=Pongo abelii GN=EIF2S2 PE=2 SV=1
Length = 333
Score = 238 bits (607), Expect = 6e-062
Identities = 135/277 (48%), Positives = 176/277 (63%), Gaps = 15/277 (5%)
Frame = +3
Query: 195 DENNEIKEVKDEQDLAPFDPTKKKKKKKVVIQDPIEDCTESSQPEKSDS-----LPANDG 359
+E+ K+ D+ D F KKKKKK I D I++ E + K +S D
Sbjct: 58 EEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFD-IDEAEEGVKDLKIESDVQEPTEPEDD 116
Query: 360 LESSFAGLKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQQRYPWE 539
L+ G KKKKKK V+ +E L+ E L++ +D + +GI Q W
Sbjct: 117 LD-IMLGNKKKKKKNVKFPD--EDEILEKDEALED---EDNKKDDGISFSNQTGP--AWA 168
Query: 540 GSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKT 716
GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK
Sbjct: 169 GSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKL 228
Query: 717 MHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPD 896
+HRQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPD
Sbjct: 229 LHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPD 288
Query: 897 TILSKENRLFFLRCEKCGSGRSVAQIKAGFVARVGRR 1007
TIL K+ RL+FL+CE C S S A IK GF A G+R
Sbjct: 289 TILQKDTRLYFLQCETCHSRCSAASIKTGFQAVTGKR 325
>sp|P56329|IF2B_SCHPO Probable eukaryotic translation initiation factor 2
subunit beta OS=Schizosaccharomyces pombe GN=tif212 PE=1 SV=2
Length = 321
Score = 231 bits (588), Expect = 1e-059
Identities = 125/268 (46%), Positives = 160/268 (59%), Gaps = 21/268 (7%)
Frame = +3
Query: 207 EIKEVKDEQDLAPFDPTKKKKKKKVVIQDPIEDCTESSQPEKSDSLPANDGLESSFAGLK 386
E+ E+KD F KKKKK K + +S E+++ + G E F+ +K
Sbjct: 72 EVDELKD-----MFSSMKKKKKSKK---------SSASAEEQTEDITTESG-ELDFSSMK 116
Query: 387 KKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQQRYPWEGSDRDYIYD 566
KKKKK S E+ L+ + D D + + W SDRDY Y
Sbjct: 117 KKKKKKKSADLSAFEKELEASS-----TGDATSDLSKQTFDSENMGEHAWLKSDRDYYYP 171
Query: 567 ELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMN 746
ELL R F +LR NNPELAG++R+ + PP V REG KKT+F N D+ K MHR DHV+
Sbjct: 172 ELLNRFFTLLRTNNPELAGEKRKYTIVPPSVHREG-KKTIFANISDISKRMHRSLDHVIQ 230
Query: 747 FLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLF 926
FL AELGTSGS+DG RL++KGRF K E +LRRY+ EYV C CKSPDTIL+KENR+F
Sbjct: 231 FLFAELGTSGSVDGSSRLIIKGRFQQKQIENVLRRYIVEYVTCKTCKSPDTILTKENRIF 290
Query: 927 FLRCEKCGSGRSVAQIKAGFVARVGRRK 1010
F+ CE CGS RSV IK G+ A++G+RK
Sbjct: 291 FMTCEACGSVRSVQAIKTGYQAQIGKRK 318
>sp|A6NK07|IF2BL_HUMAN Eukaryotic translation initiation factor 2 subunit 2-like
protein OS=Homo sapiens PE=1 SV=1
Length = 327
Score = 219 bits (557), Expect = 4e-056
Identities = 105/184 (57%), Positives = 137/184 (74%), Gaps = 1/184 (0%)
Frame = +3
Query: 459 DEHANDDEEDAEGIDLQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRR 635
++ A +DE++ + + Q W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+
Sbjct: 136 EDEALEDEDNKKDDGISFSNQTGPAWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRK 195
Query: 636 TVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGR 815
VM+PPQV+R GTKKT FVNF D+CK +HRQP H++ FLLAELGTSGS+DG +LV+KGR
Sbjct: 196 FVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGR 255
Query: 816 FAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFFLRCEKCGSGRSVAQIKAGFVAR 995
F K E +LRRY+ EYV C C+SPDTIL K+ RL+FL+CE C S SVA IK GF A
Sbjct: 256 FQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDMRLYFLQCETCHSRCSVAIIKIGFQAV 315
Query: 996 VGRR 1007
+G+R
Sbjct: 316 MGKR 319
>sp|Q54T27|IF2B_DICDI Eukaryotic translation initiation factor 2 subunit 2
OS=Dictyostelium discoideum GN=eif2s2 PE=3 SV=1
Length = 317
Score = 213 bits (541), Expect = 3e-054
Identities = 113/264 (42%), Positives = 167/264 (63%), Gaps = 9/264 (3%)
Frame = +3
Query: 210 IKEVKDEQDLAPFDPTKKKKKKKVVIQDPIEDCTESSQPEKSDSLPAND-GLESSFAGLK 386
+ + +DEQ+ K+KKKK ++ + +E+ EK ++ A+D +E+ F G K
Sbjct: 44 MSQQEDEQEQEDEKKEKRKKKKAALLASTEGENSEAI--EKLENEGAHDEDIEAEFMGEK 101
Query: 387 KKKKKPVEIS-SSLNEESLDTAEDLDEHANDDEEDAEGI----DLQQQQQQRYPWEGSDR 551
KKKKK + S ++ + T E + +D E E D Q PW G+DR
Sbjct: 102 KKKKKSSKSSTTTTTSTTTTTTEPTETEPTEDGESKEKTITTSDGDTFVQGTIPWAGTDR 161
Query: 552 DYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQP 731
DY Y EL R++++L+ NNP+L D++RT M+PPQV+REGTKKT++ NF ++C T++R+
Sbjct: 162 DYKYSELTYRIYHLLQANNPDLISDQKRT-MKPPQVMREGTKKTIWANFAEICGTLNRKV 220
Query: 732 DHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSK 911
+HV N++ AELGT+GS+DG QRLV++GRF E ++R Y++EYV C CKSP+T+L +
Sbjct: 221 EHVYNYVFAELGTNGSIDGNQRLVIRGRFKTSQIEIVIRHYISEYVACRNCKSPNTVLER 280
Query: 912 ENRLFFLRCEKCGSGRSVAQIKAG 983
NRL+FL C C S RSVA IK G
Sbjct: 281 NNRLYFLCCNACNSKRSVAVIKKG 304
>sp|P09064|IF2B_YEAST Eukaryotic translation initiation factor 2 subunit beta
OS=Saccharomyces cerevisiae GN=SUI3 PE=1 SV=2
Length = 285
Score = 186 bits (472), Expect = 3e-046
Identities = 110/236 (46%), Positives = 143/236 (60%), Gaps = 16/236 (6%)
Frame = +3
Query: 318 SQPEKSDSLPANDGLES-SFAGLKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAE 494
S +++ P +D E+ LKKKKKK + S E+ L A LD + +E
Sbjct: 59 SADAEAEKEPTDDIAEALGELSLKKKKKKTKDSSVDAFEKELAKA-GLDNVDAESKEGTP 117
Query: 495 GIDLQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMR--PPQVLRE 668
+ QQ+ P Y ELL R FNILR NNPELAGDR R PP LR+
Sbjct: 118 SANSSIQQEVGLP---------YSELLSRFFNILRTNNPELAGDRSGPKFRIPPPVCLRD 168
Query: 669 GTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILR 848
G KKT+F N D+ + +HR P+H++ +L AELGTSGS+DGQ+RLV+KG+F K E +LR
Sbjct: 169 G-KKTIFSNIQDIAEKLHRSPEHLIQYLFAELGTSGSVDGQKRLVIKGKFQSKQMENVLR 227
Query: 849 RYVTEYVICLGCKSPDTILSKE--NRLFFLRCEKCGSGRSVAQIKAGFVARVGRRK 1010
RY+ EYV C CKS +T L +E NRLFF+ C+ CGS RSV+ IK GF A VG+R+
Sbjct: 228 RYILEYVTCKTCKSINTELKREQSNRLFFMVCKSCGSTRSVSSIKTGFQATVGKRR 283
>sp|Q21230|IF2B_CAEEL Eukaryotic translation initiation factor 2 subunit 2
OS=Caenorhabditis elegans GN=K04G2.1 PE=3 SV=4
Length = 250
Score = 180 bits (456), Expect = 2e-044
Identities = 84/176 (47%), Positives = 122/176 (69%)
Frame = +3
Query: 480 EEDAEGIDLQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQV 659
EE +++ Q +G+ DY Y+E L V+ ++++ NP+ AGD+++ ++ P+V
Sbjct: 62 EEKVPTLEIGIGAQNLIDAKGAWPDYTYEEALTLVYQVMKDKNPDFAGDKKKFAIKLPEV 121
Query: 660 LREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEG 839
R G+KKT F NF+++C+ M RQ HV+ FLLAELGT+GS+DG L+VKGR+ K FE
Sbjct: 122 ARAGSKKTAFSNFLEICRLMKRQDKHVLQFLLAELGTTGSIDGSNCLIVKGRWQQKQFES 181
Query: 840 ILRRYVTEYVICLGCKSPDTILSKENRLFFLRCEKCGSGRSVAQIKAGFVARVGRR 1007
+LR+Y+ EYV+C CKSP+T L+K+ RLFFL+C CGS SV IK+GF A VG+R
Sbjct: 182 VLRKYIKEYVMCHTCKSPETQLTKDTRLFFLQCTNCGSRCSVTAIKSGFKAVVGKR 237
>sp|C5A2A8|IF2B_THEGJ Translation initiation factor 2 subunit beta
OS=Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)
GN=eIF2B PE=3 SV=1
Length = 142
Score = 103 bits (256), Expect = 3e-021
Identities = 49/133 (36%), Positives = 81/133 (60%), Gaps = 5/133 (3%)
Frame = +3
Query: 555 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 734
Y ++ LL + + E PE + PP V+ +T+ NF+D+ + M+R P
Sbjct: 8 YDFERLLDKAY----EELPENVKSHKSRFEVPPAVVTIAGNRTIIENFVDIAEAMNRDPS 63
Query: 735 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 914
H++ F+L E+ T+G+L+G +R++++GRF P L++Y+ EYVIC C SPDT + K
Sbjct: 64 HLLKFILREVATAGTLEG-RRVILQGRFTPYLIANKLKKYLKEYVICPVCGSPDTKIIKR 122
Query: 915 NRLFFLRCEKCGS 953
+R +FL+CE CG+
Sbjct: 123 DRFYFLKCEACGA 135
>sp|O58312|IF2B_PYRHO Translation initiation factor 2 subunit beta OS=Pyrococcus
horikoshii GN=eif2b PE=3 SV=1
Length = 140
Score = 102 bits (252), Expect = 9e-021
Identities = 53/133 (39%), Positives = 83/133 (62%), Gaps = 5/133 (3%)
Frame = +3
Query: 555 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 734
Y Y++LL + + L EN + + R + V EG KT+ NF D+ + ++R P
Sbjct: 6 YDYEKLLEKAYEELPEN---VKHHKSRFEVPGALVTIEG-NKTIIENFKDIAEALNRDPQ 61
Query: 735 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 914
H++ FLL E+ T+G+L+G +R+V++GRF P L++Y+ EYVIC C SPDT + K
Sbjct: 62 HLLKFLLREIATAGTLEG-KRVVLQGRFTPYLIANKLKKYIKEYVICPVCGSPDTKIIKR 120
Query: 915 NRLFFLRCEKCGS 953
+R +FL+CE CG+
Sbjct: 121 DRFYFLKCEACGA 133
>sp|Q9UYR6|IF2B_PYRAB Translation initiation factor 2 subunit beta OS=Pyrococcus
abyssi GN=eif2b PE=3 SV=1
Length = 140
Score = 101 bits (250), Expect = 2e-020
Identities = 52/133 (39%), Positives = 83/133 (62%), Gaps = 5/133 (3%)
Frame = +3
Query: 555 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 734
Y Y++LL + + L EN + + R + V EG KT+ NF D+ + ++R P
Sbjct: 6 YDYEKLLEKAYEELPEN---VKHHKSRFEVPGALVTIEG-NKTIIENFKDIAEALNRDPQ 61
Query: 735 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 914
H++ FLL E+ T+G+L+G +R+V++GRF P +++Y+ EYVIC C SPDT + K
Sbjct: 62 HLLKFLLREIATAGTLEG-KRVVLQGRFTPYLIANKIKKYIKEYVICPVCGSPDTKIIKR 120
Query: 915 NRLFFLRCEKCGS 953
+R +FL+CE CG+
Sbjct: 121 DRFYFLKCEACGA 133
>sp|A2SSW2|IF2B_METLZ Translation initiation factor 2 subunit beta
OS=Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)
GN=eIF2B PE=3 SV=1
Length = 204
Score = 100 bits (248), Expect = 3e-020
Identities = 53/116 (45%), Positives = 70/116 (60%), Gaps = 2/116 (1%)
Frame = +3
Query: 633 RTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKG 812
R VM ++ EG K TV NF D+ +++R DH M F+L ELGT+G +DG R V G
Sbjct: 25 RFVMPKAKIYIEG-KTTVLENFSDIVDSLNRDKDHFMKFILGELGTAGKIDG-NRAVFNG 82
Query: 813 RFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFFLRCEKCGSGRSVAQIKA 980
+F F+ IL YV +YVIC C PDT L K++R+ L CE CGS R + + KA
Sbjct: 83 KFEQAQFDAILETYVGDYVICSECGRPDTKLVKDDRVLMLLCEACGSKRPIRKRKA 138
>sp|Q8U3I5|IF2B_PYRFU Translation initiation factor 2 subunit beta OS=Pyrococcus
furiosus GN=eif2b PE=1 SV=1
Length = 140
Score = 99 bits (246), Expect = 4e-020
Identities = 53/133 (39%), Positives = 81/133 (60%), Gaps = 5/133 (3%)
Frame = +3
Query: 555 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 734
Y Y++LL + + L EN + + R + V EG KT+ NF D+ ++R P
Sbjct: 6 YDYEKLLEKAYQELPEN---VKHHKSRFEVPGALVTIEG-NKTIIENFKDIADALNRDPQ 61
Query: 735 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 914
H++ FLL E+ T+G+L+G +R+V++GRF P L++Y+ EYVIC C SPDT + K
Sbjct: 62 HLLKFLLREIATAGTLEG-RRVVLQGRFTPYLIANKLKKYIKEYVICPVCGSPDTKIIKR 120
Query: 915 NRLFFLRCEKCGS 953
+R FL+CE CG+
Sbjct: 121 DRFHFLKCEACGA 133
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,366,676,449
Number of Sequences: 518415
Number of Extensions: 41366676449
Number of Successful Extensions: 294470065
Number of sequences better than 0.0: 0
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