BLASTX 7.6.2
Query= UN10325 /QuerySize=1508
(1507 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8W207|CSN2_ARATH COP9 signalosome complex subunit 2 OS=Arabi... 446 3e-124
sp|Q54HL6|CSN2_DICDI COP9 signalosome complex subunit 2 OS=Dicty... 323 2e-087
sp|Q6IQT4|CSN2_DANRE COP9 signalosome complex subunit 2 OS=Danio... 313 3e-084
sp|P61201|CSN2_HUMAN COP9 signalosome complex subunit 2 OS=Homo ... 312 7e-084
sp|P61202|CSN2_MOUSE COP9 signalosome complex subunit 2 OS=Mus m... 312 7e-084
sp|P61203|CSN2_RAT COP9 signalosome complex subunit 2 OS=Rattus ... 312 7e-084
sp|Q6IR75|CSN2_XENLA COP9 signalosome complex subunit 2 (Fragmen... 312 7e-084
sp|Q94899|CSN2_DROME COP9 signalosome complex subunit 2 OS=Droso... 289 7e-077
sp|Q9HFR0|CSN2_SCHPO COP9 signalosome complex subunit 2 OS=Schiz... 241 2e-062
sp|O01422|CSN2_CAEEL COP9 signalosome complex subunit 2 OS=Caeno... 235 1e-060
sp|Q5B3U7|CSN2_EMENI COP9 signalosome complex subunit 2 OS=Emeri... 232 7e-060
sp|Q7SI58|CSN2_NEUCR COP9 signalosome complex subunit 2 OS=Neuro... 228 1e-058
>sp|Q8W207|CSN2_ARATH COP9 signalosome complex subunit 2 OS=Arabidopsis thaliana
GN=CSN2 PE=1 SV=1
Length = 439
Score = 446 bits (1145), Expect = 3e-124
Identities = 225/261 (86%), Positives = 242/261 (92%), Gaps = 3/261 (1%)
Frame = +1
Query: 595 DG*SEER--SQLLEFMPLKFR-FTLKLRQQKLKQLYQKALAIKSAIPHPRIMGIIRECGG 765
DG +++ SQLLE ++ + +T +KLKQLY KALAIKSAIPHPRIMGIIRECGG
Sbjct: 179 DGTDDQKKGSQLLEVYAIEIQIYTETKDNKKLKQLYHKALAIKSAIPHPRIMGIIRECGG 238
Query: 766 KMHMAERQWAEAATDFFEAFKNYDEAGNQRRIQCLRYLVLANMLMESEVNPFDGQEAKPY 945
KMHMAERQW EAATDFFEAFKNYDEAGNQRRIQCL+YLVLANMLMESEVNPFDGQEAKPY
Sbjct: 239 KMHMAERQWEEAATDFFEAFKNYDEAGNQRRIQCLKYLVLANMLMESEVNPFDGQEAKPY 298
Query: 946 KNDPEILAMTNLVAAYQRNEIIEFEKILKNNRKTIMDDPFIRNYMEDLLKKVRTQVLLKL 1125
KNDPEILAMTNL+AAYQRNEIIEFE+ILK+NR+TIMDDPFIRNYMEDLLKKVRTQVLLKL
Sbjct: 299 KNDPEILAMTNLIAAYQRNEIIEFERILKSNRRTIMDDPFIRNYMEDLLKKVRTQVLLKL 358
Query: 1126 IKPYTKIGIPFISKELNVPEKDVTELLVSLILDSRIDGHIDEINRYLLRGDSANGRKLHK 1305
IKPYTKIGIPFISKELNVPE DVTELLVSLILDSRIDGHIDE+NRYLLRGDS NGRKLHK
Sbjct: 359 IKPYTKIGIPFISKELNVPETDVTELLVSLILDSRIDGHIDEMNRYLLRGDSGNGRKLHK 418
Query: 1306 AVDKWNTQLKSLSMSITNRVC 1368
AVDKWN+QLKSLS +IT+RVC
Sbjct: 419 AVDKWNSQLKSLSSNITSRVC 439
Score = 368 bits (943), Expect = 8e-101
Identities = 184/208 (88%), Positives = 194/208 (93%), Gaps = 1/208 (0%)
Frame = +3
Query: 57 MASDADMEDYGFEYSDEEQEEQDVDIENQYYNSKGNVETDPEEALSGFAEVVKMEPDKAE 236
MASDADMEDYGFEYSDEEQEEQDVDIENQYYNSKG VET+PEEALSGFAEVV+MEP+KA+
Sbjct: 1 MASDADMEDYGFEYSDEEQEEQDVDIENQYYNSKGMVETEPEEALSGFAEVVQMEPEKAD 60
Query: 237 WGFKALKQTVKIYYRLGKYREMMDAYREMLTYIKSAVTRNYSEKCINSIMDFVSGSASQN 416
WGFKALKQTVKIYYRLGKY+EMM+AY EMLTYIKSAVTRNYSEKCIN+IMDFVSGSASQN
Sbjct: 61 WGFKALKQTVKIYYRLGKYKEMMEAYTEMLTYIKSAVTRNYSEKCINNIMDFVSGSASQN 120
Query: 417 TGLLQEFYQTTLTALEEAKNERLWFKTNLKLCNIWFDIGEYRRMTKILKELHKSCQKKMG 596
TGLLQEFYQTTL ALEEAKNERLWFKTNLKLCNIWFDIGEYRRMTKILKELHKSCQK+ G
Sbjct: 121 TGLLQEFYQTTLKALEEAKNERLWFKTNLKLCNIWFDIGEYRRMTKILKELHKSCQKEDG 180
Query: 597 RMIRRKES-AA*VYAIEIQIYTETKTTK 677
++K S VYAIEIQIYTETK K
Sbjct: 181 TDDQKKGSQLLEVYAIEIQIYTETKDNK 208
>sp|Q54HL6|CSN2_DICDI COP9 signalosome complex subunit 2 OS=Dictyostelium
discoideum GN=csn2 PE=1 SV=1
Length = 449
Score = 323 bits (827), Expect = 2e-087
Identities = 165/261 (63%), Positives = 205/261 (78%), Gaps = 4/261 (1%)
Frame = +1
Query: 595 DG*SEER--SQLLEFMPLKFR-FTLKLRQQKLKQLYQKALAIKSAIPHPRIMGIIRECGG 765
DG +++ SQL++ L+ + +T +KLK LY+KAL IKSAIPHPRIMGIIRECGG
Sbjct: 187 DGTDDQKKGSQLVDIYALEIQMYTETKNNKKLKDLYKKALEIKSAIPHPRIMGIIRECGG 246
Query: 766 KMHMAERQWAEAATDFFEAFKNYDEAGNQRRIQCLRYLVLANMLMESEVNPFDGQEAKPY 945
KMHMAE++W +A TDFFEAFKNYDEAGN RRIQCL+YLVLA MLM S +NPFD EAKPY
Sbjct: 247 KMHMAEKEWEKAHTDFFEAFKNYDEAGNSRRIQCLKYLVLACMLMLSTINPFDSTEAKPY 306
Query: 946 KNDPEILAMTNLVAAYQRNEIIEFEKILKNNRKTIMDDPFIRNYMEDLLKKVRTQVLLKL 1125
KNDP+ILAMTNLV AY++N+I FEKILK+NRKTIMDDPFIR Y+EDLL+ +RTQVLLKL
Sbjct: 307 KNDPDILAMTNLVMAYEKNDIYAFEKILKDNRKTIMDDPFIRMYIEDLLRNIRTQVLLKL 366
Query: 1126 IKPYTKIGIPFISKELNVPEKDVTELLVSLILDSRIDGHIDEINRYL-LRGDSANGRKLH 1302
+KPYT+I I FISKELN+P DV LLVSLILD++I G ID++N+ L L ++ +
Sbjct: 367 LKPYTRIRISFISKELNIPSSDVESLLVSLILDNKIRGSIDQVNQQLELDTAKSSAYWKY 426
Query: 1303 KAVDKWNTQLKSLSMSITNRV 1365
++ KW Q+ L+ I N++
Sbjct: 427 TSIHKWANQIGQLNGGINNKL 447
>sp|Q6IQT4|CSN2_DANRE COP9 signalosome complex subunit 2 OS=Danio rerio GN=cops2
PE=2 SV=1
Length = 443
Score = 313 bits (800), Expect = 3e-084
Identities = 154/251 (61%), Positives = 195/251 (77%), Gaps = 1/251 (0%)
Frame = +1
Query: 616 SQLLEFMPLKFR-FTLKLRQQKLKQLYQKALAIKSAIPHPRIMGIIRECGGKMHMAERQW 792
+QLLE L+ + +T + +KLK LY+++L IKSAIPHP IMG+IRECGGKMH+ E ++
Sbjct: 192 TQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEF 251
Query: 793 AEAATDFFEAFKNYDEAGNQRRIQCLRYLVLANMLMESEVNPFDGQEAKPYKNDPEILAM 972
+A TDFFEAFKNYDE+G+ RR CL+YLVLANMLM+S +NPFD QEAKPYKNDPEILAM
Sbjct: 252 EKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAM 311
Query: 973 TNLVAAYQRNEIIEFEKILKNNRKTIMDDPFIRNYMEDLLKKVRTQVLLKLIKPYTKIGI 1152
TNLV+AYQ N+I EFEKILK N IMDDPFIR ++E+LL+ +RTQVL+KLIKPYT+I I
Sbjct: 312 TNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHI 371
Query: 1153 PFISKELNVPEKDVTELLVSLILDSRIDGHIDEINRYLLRGDSANGRKLHKAVDKWNTQL 1332
PFISKELN+ DV LLV ILD+ I+G ID++N+ L G + A+DKW QL
Sbjct: 372 PFISKELNIDVADVESLLVQCILDNTINGRIDQVNQLLELDHQKRGGARYTALDKWTNQL 431
Query: 1333 KSLSMSITNRV 1365
SL+ +I +++
Sbjct: 432 NSLNQAIVSKL 442
Score = 219 bits (557), Expect = 5e-056
Identities = 108/214 (50%), Positives = 153/214 (71%), Gaps = 3/214 (1%)
Frame = +3
Query: 72 DMEDYGFEYSDEEQEEQDVDIENQYYNSKGNVETDPEEALSGFAEVVKMEPDKAEWGFKA 251
D EDY EYS++ E +VD+ENQYYNSK E DP+ ALS F +V+++E +K EWGFKA
Sbjct: 12 DEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKA 71
Query: 252 LKQTVKIYYRLGKYREMMDAYREMLTYIKSAVTRNYSEKCINSIMDFVSGSASQNTGLLQ 431
LKQ +KI ++L + EMM+ Y+++LTYI+SAVTRNYSEK INSI+D++ S S+ LLQ
Sbjct: 72 LKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYI--STSKQMDLLQ 129
Query: 432 EFYQTTLTALEEAKNERLWFKTNLKLCNIWFDIGEYRRMTKILKELHKSCQKKMGR-MIR 608
EFY+TTL AL++AKN+RLWFKTN KL ++ + E+ ++ KIL++LH+SCQ G ++
Sbjct: 130 EFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEFGKLQKILRQLHQSCQTDDGEDDLK 189
Query: 609 RKESAA*VYAIEIQIYTETKTTKAQATVPESTCY 710
+ +YA+EIQ+YT K K + E + +
Sbjct: 190 KGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLH 223
>sp|P61201|CSN2_HUMAN COP9 signalosome complex subunit 2 OS=Homo sapiens
GN=COPS2 PE=1 SV=1
Length = 443
Score = 312 bits (797), Expect = 7e-084
Identities = 153/251 (60%), Positives = 194/251 (77%), Gaps = 1/251 (0%)
Frame = +1
Query: 616 SQLLEFMPLKFR-FTLKLRQQKLKQLYQKALAIKSAIPHPRIMGIIRECGGKMHMAERQW 792
+QLLE L+ + +T + +KLK LY+++L IKSAIPHP IMG+IRECGGKMH+ E ++
Sbjct: 192 TQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEF 251
Query: 793 AEAATDFFEAFKNYDEAGNQRRIQCLRYLVLANMLMESEVNPFDGQEAKPYKNDPEILAM 972
+A TDFFEAFKNYDE+G+ RR CL+YLVLANMLM+S +NPFD QEAKPYKNDPEILAM
Sbjct: 252 EKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAM 311
Query: 973 TNLVAAYQRNEIIEFEKILKNNRKTIMDDPFIRNYMEDLLKKVRTQVLLKLIKPYTKIGI 1152
TNLV+AYQ N+I EFEKILK N IMDDPFIR ++E+LL+ +RTQVL+KLIKPYT+I I
Sbjct: 312 TNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHI 371
Query: 1153 PFISKELNVPEKDVTELLVSLILDSRIDGHIDEINRYLLRGDSANGRKLHKAVDKWNTQL 1332
PFISKELN+ DV LLV ILD+ I G ID++N+ L G + A+DKW QL
Sbjct: 372 PFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQL 431
Query: 1333 KSLSMSITNRV 1365
SL+ ++ +++
Sbjct: 432 NSLNQAVVSKL 442
Score = 221 bits (561), Expect = 2e-056
Identities = 109/214 (50%), Positives = 153/214 (71%), Gaps = 3/214 (1%)
Frame = +3
Query: 72 DMEDYGFEYSDEEQEEQDVDIENQYYNSKGNVETDPEEALSGFAEVVKMEPDKAEWGFKA 251
D EDY EYS++ E +VD+ENQYYNSK E DP+ ALS F +V+++E +K EWGFKA
Sbjct: 12 DEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKA 71
Query: 252 LKQTVKIYYRLGKYREMMDAYREMLTYIKSAVTRNYSEKCINSIMDFVSGSASQNTGLLQ 431
LKQ +KI ++L + EMM+ Y+++LTYI+SAVTRNYSEK INSI+D++ S S+ LLQ
Sbjct: 72 LKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYI--STSKQMDLLQ 129
Query: 432 EFYQTTLTALEEAKNERLWFKTNLKLCNIWFDIGEYRRMTKILKELHKSCQKKMGR-MIR 608
EFY+TTL AL++AKN+RLWFKTN KL ++ + EY ++ KIL++LH+SCQ G ++
Sbjct: 130 EFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLK 189
Query: 609 RKESAA*VYAIEIQIYTETKTTKAQATVPESTCY 710
+ +YA+EIQ+YT K K + E + +
Sbjct: 190 KGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLH 223
>sp|P61202|CSN2_MOUSE COP9 signalosome complex subunit 2 OS=Mus musculus
GN=Cops2 PE=1 SV=1
Length = 443
Score = 312 bits (797), Expect = 7e-084
Identities = 153/251 (60%), Positives = 194/251 (77%), Gaps = 1/251 (0%)
Frame = +1
Query: 616 SQLLEFMPLKFR-FTLKLRQQKLKQLYQKALAIKSAIPHPRIMGIIRECGGKMHMAERQW 792
+QLLE L+ + +T + +KLK LY+++L IKSAIPHP IMG+IRECGGKMH+ E ++
Sbjct: 192 TQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEF 251
Query: 793 AEAATDFFEAFKNYDEAGNQRRIQCLRYLVLANMLMESEVNPFDGQEAKPYKNDPEILAM 972
+A TDFFEAFKNYDE+G+ RR CL+YLVLANMLM+S +NPFD QEAKPYKNDPEILAM
Sbjct: 252 EKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAM 311
Query: 973 TNLVAAYQRNEIIEFEKILKNNRKTIMDDPFIRNYMEDLLKKVRTQVLLKLIKPYTKIGI 1152
TNLV+AYQ N+I EFEKILK N IMDDPFIR ++E+LL+ +RTQVL+KLIKPYT+I I
Sbjct: 312 TNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHI 371
Query: 1153 PFISKELNVPEKDVTELLVSLILDSRIDGHIDEINRYLLRGDSANGRKLHKAVDKWNTQL 1332
PFISKELN+ DV LLV ILD+ I G ID++N+ L G + A+DKW QL
Sbjct: 372 PFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQL 431
Query: 1333 KSLSMSITNRV 1365
SL+ ++ +++
Sbjct: 432 NSLNQAVVSKL 442
Score = 221 bits (561), Expect = 2e-056
Identities = 109/214 (50%), Positives = 153/214 (71%), Gaps = 3/214 (1%)
Frame = +3
Query: 72 DMEDYGFEYSDEEQEEQDVDIENQYYNSKGNVETDPEEALSGFAEVVKMEPDKAEWGFKA 251
D EDY EYS++ E +VD+ENQYYNSK E DP+ ALS F +V+++E +K EWGFKA
Sbjct: 12 DEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKA 71
Query: 252 LKQTVKIYYRLGKYREMMDAYREMLTYIKSAVTRNYSEKCINSIMDFVSGSASQNTGLLQ 431
LKQ +KI ++L + EMM+ Y+++LTYI+SAVTRNYSEK INSI+D++ S S+ LLQ
Sbjct: 72 LKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYI--STSKQMDLLQ 129
Query: 432 EFYQTTLTALEEAKNERLWFKTNLKLCNIWFDIGEYRRMTKILKELHKSCQKKMGR-MIR 608
EFY+TTL AL++AKN+RLWFKTN KL ++ + EY ++ KIL++LH+SCQ G ++
Sbjct: 130 EFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLK 189
Query: 609 RKESAA*VYAIEIQIYTETKTTKAQATVPESTCY 710
+ +YA+EIQ+YT K K + E + +
Sbjct: 190 KGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLH 223
>sp|P61203|CSN2_RAT COP9 signalosome complex subunit 2 OS=Rattus norvegicus
GN=Cops2 PE=2 SV=1
Length = 443
Score = 312 bits (797), Expect = 7e-084
Identities = 153/251 (60%), Positives = 194/251 (77%), Gaps = 1/251 (0%)
Frame = +1
Query: 616 SQLLEFMPLKFR-FTLKLRQQKLKQLYQKALAIKSAIPHPRIMGIIRECGGKMHMAERQW 792
+QLLE L+ + +T + +KLK LY+++L IKSAIPHP IMG+IRECGGKMH+ E ++
Sbjct: 192 TQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEF 251
Query: 793 AEAATDFFEAFKNYDEAGNQRRIQCLRYLVLANMLMESEVNPFDGQEAKPYKNDPEILAM 972
+A TDFFEAFKNYDE+G+ RR CL+YLVLANMLM+S +NPFD QEAKPYKNDPEILAM
Sbjct: 252 EKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAM 311
Query: 973 TNLVAAYQRNEIIEFEKILKNNRKTIMDDPFIRNYMEDLLKKVRTQVLLKLIKPYTKIGI 1152
TNLV+AYQ N+I EFEKILK N IMDDPFIR ++E+LL+ +RTQVL+KLIKPYT+I I
Sbjct: 312 TNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHI 371
Query: 1153 PFISKELNVPEKDVTELLVSLILDSRIDGHIDEINRYLLRGDSANGRKLHKAVDKWNTQL 1332
PFISKELN+ DV LLV ILD+ I G ID++N+ L G + A+DKW QL
Sbjct: 372 PFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQL 431
Query: 1333 KSLSMSITNRV 1365
SL+ ++ +++
Sbjct: 432 NSLNQAVVSKL 442
Score = 221 bits (561), Expect = 2e-056
Identities = 109/214 (50%), Positives = 153/214 (71%), Gaps = 3/214 (1%)
Frame = +3
Query: 72 DMEDYGFEYSDEEQEEQDVDIENQYYNSKGNVETDPEEALSGFAEVVKMEPDKAEWGFKA 251
D EDY EYS++ E +VD+ENQYYNSK E DP+ ALS F +V+++E +K EWGFKA
Sbjct: 12 DEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKA 71
Query: 252 LKQTVKIYYRLGKYREMMDAYREMLTYIKSAVTRNYSEKCINSIMDFVSGSASQNTGLLQ 431
LKQ +KI ++L + EMM+ Y+++LTYI+SAVTRNYSEK INSI+D++ S S+ LLQ
Sbjct: 72 LKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYI--STSKQMDLLQ 129
Query: 432 EFYQTTLTALEEAKNERLWFKTNLKLCNIWFDIGEYRRMTKILKELHKSCQKKMGR-MIR 608
EFY+TTL AL++AKN+RLWFKTN KL ++ + EY ++ KIL++LH+SCQ G ++
Sbjct: 130 EFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLK 189
Query: 609 RKESAA*VYAIEIQIYTETKTTKAQATVPESTCY 710
+ +YA+EIQ+YT K K + E + +
Sbjct: 190 KGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLH 223
>sp|Q6IR75|CSN2_XENLA COP9 signalosome complex subunit 2 (Fragment) OS=Xenopus
laevis GN=csn2 PE=2 SV=1
Length = 441
Score = 312 bits (797), Expect = 7e-084
Identities = 153/251 (60%), Positives = 194/251 (77%), Gaps = 1/251 (0%)
Frame = +1
Query: 616 SQLLEFMPLKFR-FTLKLRQQKLKQLYQKALAIKSAIPHPRIMGIIRECGGKMHMAERQW 792
+QLLE L+ + +T + +KLK LY+++L IKSAIPHP IMG+IRECGGKMH+ E ++
Sbjct: 190 TQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEF 249
Query: 793 AEAATDFFEAFKNYDEAGNQRRIQCLRYLVLANMLMESEVNPFDGQEAKPYKNDPEILAM 972
+A TDFFEAFKNYDE+G+ RR CL+YLVLANMLM+S +NPFD QEAKPYKNDPEILAM
Sbjct: 250 EKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAM 309
Query: 973 TNLVAAYQRNEIIEFEKILKNNRKTIMDDPFIRNYMEDLLKKVRTQVLLKLIKPYTKIGI 1152
TNLV+AYQ N+I EFEKILK N IMDDPFIR ++E+LL+ +RTQVL+KLIKPYT+I I
Sbjct: 310 TNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHI 369
Query: 1153 PFISKELNVPEKDVTELLVSLILDSRIDGHIDEINRYLLRGDSANGRKLHKAVDKWNTQL 1332
PFISKELN+ DV LLV ILD+ I G ID++N+ L G + A+DKW QL
Sbjct: 370 PFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQL 429
Query: 1333 KSLSMSITNRV 1365
SL+ ++ +++
Sbjct: 430 NSLNQAVVSKL 440
Score = 225 bits (573), Expect = 7e-058
Identities = 111/214 (51%), Positives = 154/214 (71%), Gaps = 3/214 (1%)
Frame = +3
Query: 72 DMEDYGFEYSDEEQEEQDVDIENQYYNSKGNVETDPEEALSGFAEVVKMEPDKAEWGFKA 251
D EDY EYS++ E +VD+ENQYYNSK E DP+ ALS F +V+++E +K EWGFKA
Sbjct: 10 DEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKA 69
Query: 252 LKQTVKIYYRLGKYREMMDAYREMLTYIKSAVTRNYSEKCINSIMDFVSGSASQNTGLLQ 431
LKQ +KI ++LG Y EMM+ Y+++LTYI+SAVTRNYSEK INSI+D++ S S+ LLQ
Sbjct: 70 LKQMIKINFKLGNYPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYI--STSKQMDLLQ 127
Query: 432 EFYQTTLTALEEAKNERLWFKTNLKLCNIWFDIGEYRRMTKILKELHKSCQKKMGR-MIR 608
EFY+TTL AL++AKN+RLWFKTN KL ++ + EY ++ KIL++LH+SCQ G ++
Sbjct: 128 EFYETTLDALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLK 187
Query: 609 RKESAA*VYAIEIQIYTETKTTKAQATVPESTCY 710
+ +YA+EIQ+YT K K + E + +
Sbjct: 188 KGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLH 221
>sp|Q94899|CSN2_DROME COP9 signalosome complex subunit 2 OS=Drosophila
melanogaster GN=alien PE=1 SV=2
Length = 444
Score = 289 bits (737), Expect = 7e-077
Identities = 141/251 (56%), Positives = 188/251 (74%), Gaps = 1/251 (0%)
Frame = +1
Query: 616 SQLLEFMPLKFR-FTLKLRQQKLKQLYQKALAIKSAIPHPRIMGIIRECGGKMHMAERQW 792
+QLLE L+ + +T++ +KLK LY+++L IKSAIPHP IMG+IRECGGKMH+ E ++
Sbjct: 193 TQLLEIYALEIQMYTVQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEF 252
Query: 793 AEAATDFFEAFKNYDEAGNQRRIQCLRYLVLANMLMESEVNPFDGQEAKPYKNDPEILAM 972
+A TDFFEAFKNYDE+G+ RR CL+YLVLANMLM+S +NPFD QEAKPYKNDPEILAM
Sbjct: 253 EKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAM 312
Query: 973 TNLVAAYQRNEIIEFEKILKNNRKTIMDDPFIRNYMEDLLKKVRTQVLLKLIKPYTKIGI 1152
TNLV +YQ N+I EFE IL+ +R IM D FIR ++EDLL+ +RTQVL+KLI+PY I I
Sbjct: 313 TNLVNSYQNNDINEFETILRQHRSNIMADQFIREHIEDLLRNIRTQVLIKLIRPYKNIAI 372
Query: 1153 PFISKELNVPEKDVTELLVSLILDSRIDGHIDEINRYLLRGDSANGRKLHKAVDKWNTQL 1332
PFI+ LN+ +V LLVS ILD I G ID++N+ L + + A++KW+ Q+
Sbjct: 373 PFIANALNIEPAEVESLLVSCILDDTIKGRIDQVNQVLQLDKINSSASRYNALEKWSNQI 432
Query: 1333 KSLSMSITNRV 1365
+SL ++ ++
Sbjct: 433 QSLQFAVVQKM 443
Score = 220 bits (560), Expect = 2e-056
Identities = 112/215 (52%), Positives = 152/215 (70%), Gaps = 4/215 (1%)
Frame = +3
Query: 72 DMEDYGFEYSDEEQEEQDVDIENQYYNSKGNVETDPEEALSGFAEVVKME-PDKAEWGFK 248
D EDYG EYS++ E DVD+ENQYYNSK E +P+ AL+ F +V+ +E +K EWGFK
Sbjct: 12 DDEDYGLEYSEDSNSEPDVDLENQYYNSKALKEEEPKAALASFQKVLDLENGEKGEWGFK 71
Query: 249 ALKQTVKIYYRLGKYREMMDAYREMLTYIKSAVTRNYSEKCINSIMDFVSGSASQNTGLL 428
ALKQ +KI +RL Y EMM Y+++LTYIKSAVTRN+SEK INSI+D++ S S+N LL
Sbjct: 72 ALKQMIKINFRLCNYDEMMVRYKQLLTYIKSAVTRNHSEKSINSILDYI--STSKNMALL 129
Query: 429 QEFYQTTLTALEEAKNERLWFKTNLKLCNIWFDIGEYRRMTKILKELHKSCQKKMGR-MI 605
Q FY+TTL AL +AKN+RLWFKTN KL ++FD ++ ++ KILK+LH+SCQ G +
Sbjct: 130 QNFYETTLDALRDAKNDRLWFKTNTKLGKLYFDRSDFTKLQKILKQLHQSCQTDDGEDDL 189
Query: 606 RRKESAA*VYAIEIQIYTETKTTKAQATVPESTCY 710
++ +YA+EIQ+YT K K + E + +
Sbjct: 190 KKGTQLLEIYALEIQMYTVQKNNKKLKALYEQSLH 224
>sp|Q9HFR0|CSN2_SCHPO COP9 signalosome complex subunit 2 OS=Schizosaccharomyces
pombe GN=csn2 PE=1 SV=1
Length = 437
Score = 241 bits (613), Expect = 2e-062
Identities = 122/244 (50%), Positives = 168/244 (68%), Gaps = 4/244 (1%)
Frame = +1
Query: 616 SQLLEFMPLKFRFTLKLRQQK-LKQLYQKALAIKSAIPHPRIMGIIRECGGKMHMAERQW 792
+ LLE L+ + + K LK+LYQ +L +K+AIPHPRIMGIIRECGGKMHM E QW
Sbjct: 194 THLLELYSLEIQMYSDIEDNKRLKELYQSSLRVKTAIPHPRIMGIIRECGGKMHMQENQW 253
Query: 793 AEAATDFFEAFKNYDEAGNQRRIQCLRYLVLANMLMESEVNPFDGQEAKPYKNDPEILAM 972
+EA T+FFE+FK+YDEAG+ RI+ L+YLVLANML ESE+NPFD E +PYK++P I+AM
Sbjct: 254 SEAQTNFFESFKSYDEAGSSDRIRVLKYLVLANMLSESEINPFDSPETQPYKDNPHIIAM 313
Query: 973 TNLVAAYQRNEIIEFEKILKNNRKTIMDDPFIRNYMEDLLKKVRTQVLLKLIKPYTKIGI 1152
T LV AYQ +I E+IL+ + I+DD FIR Y++ +L +R+QVL++L+KPYT + +
Sbjct: 314 TKLVEAYQIRDITAVERILQTYQHDILDDDFIRQYVDKILYSIRSQVLIELVKPYTSVKL 373
Query: 1153 PFISKELNVPEKDVTELLVSLILDSRIDGHIDEINRYLLRGDSAN--GRKLHKAVDK-WN 1323
++K+L V + + LV LI+D R++G ID +N N +L + V K WN
Sbjct: 374 SLLAKKLGVSISIIEQALVGLIIDERVNGKIDMVNEVFTISQPKNTIHNQLVEDVQKLWN 433
Query: 1324 TQLK 1335
T K
Sbjct: 434 TATK 437
>sp|O01422|CSN2_CAEEL COP9 signalosome complex subunit 2 OS=Caenorhabditis
elegans GN=csn-2 PE=1 SV=2
Length = 495
Score = 235 bits (597), Expect = 1e-060
Identities = 115/216 (53%), Positives = 164/216 (75%), Gaps = 4/216 (1%)
Frame = +1
Query: 616 SQLLEFMPLKFR-FTLKLRQQKLKQLYQ---KALAIKSAIPHPRIMGIIRECGGKMHMAE 783
+QLLE L+ + +T + + LK +Y+ +A+ KSAIPHP I+G IRECGGKMH+ +
Sbjct: 189 TQLLEIYALEIQMYTEQKNNKALKWVYELATQAIHTKSAIPHPLILGTIRECGGKMHLRD 248
Query: 784 RQWAEAATDFFEAFKNYDEAGNQRRIQCLRYLVLANMLMESEVNPFDGQEAKPYKNDPEI 963
++ +A TDFFEAFKNYDE+G+ RR CL+YLVLANML++S++NPFD QEAKP+KN+PEI
Sbjct: 249 GRFLDAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLIKSDINPFDSQEAKPFKNEPEI 308
Query: 964 LAMTNLVAAYQRNEIIEFEKILKNNRKTIMDDPFIRNYMEDLLKKVRTQVLLKLIKPYTK 1143
+AMT +V AYQ N+I FE+I+ ++ +IM DPFIR + E+L+ +RTQVLL+LI+PYT
Sbjct: 309 VAMTQMVQAYQDNDIQAFEQIMAAHQDSIMADPFIREHTEELMNNIRTQVLLRLIRPYTN 368
Query: 1144 IGIPFISKELNVPEKDVTELLVSLILDSRIDGHIDE 1251
+ I ++S++L V +K+V LLV ILD ++ I+E
Sbjct: 369 VRISYLSQKLKVSQKEVIHLLVDAILDDGLEAKINE 404
Score = 214 bits (544), Expect = 2e-054
Identities = 111/225 (49%), Positives = 154/225 (68%), Gaps = 4/225 (1%)
Frame = +3
Query: 72 DMEDYGFEYSDEEQEEQDVDIENQYYNSKG-NVETDPEEALSGFAEVVKMEPDKAEWGFK 248
D EDYGFEY D+ E DVD+ENQYY +KG + +EA+ F +V+++E +K EWGFK
Sbjct: 8 DDEDYGFEYEDDSGSEPDVDMENQYYTAKGLRSDGKLDEAIKSFEKVLELEGEKGEWGFK 67
Query: 249 ALKQTVKIYYRLGKYREMMDAYREMLTYIKSAVTRNYSEKCINSIMDFVSGSASQNTGLL 428
ALKQ +KI + + +M++ YR++LTYIKSAVT+NYSEK IN+I+D++ S S+ LL
Sbjct: 68 ALKQMIKITFGQNRLEKMLEYYRQLLTYIKSAVTKNYSEKSINAILDYI--STSRQMDLL 125
Query: 429 QEFYQTTLTALEEAKNERLWFKTNLKLCNIWFDIGEYRRMTKILKELHKSCQKKMGRMIR 608
Q FY+TTL AL++AKNERLWFKTN KL ++FD+ E+ ++ KI+K+L SC+ + G +
Sbjct: 126 QHFYETTLDALKDAKNERLWFKTNTKLGKLFFDLHEFTKLEKIVKQLKVSCKNEQGEEDQ 185
Query: 609 RK-ESAA*VYAIEIQIYTETKTTKAQATVPESTCYQICYSSS*DH 740
RK +YA+EIQ+YTE K KA V E I S+ H
Sbjct: 186 RKGTQLLEIYALEIQMYTEQKNNKALKWVYELATQAIHTKSAIPH 230
>sp|Q5B3U7|CSN2_EMENI COP9 signalosome complex subunit 2 OS=Emericella nidulans
GN=csnB PE=1 SV=2
Length = 506
Score = 232 bits (590), Expect = 7e-060
Identities = 112/241 (46%), Positives = 172/241 (71%), Gaps = 3/241 (1%)
Frame = +1
Query: 622 LLEFMPLKFRFTLKLRQQK-LKQLYQKALAIKSAIPHPRIMGIIRECGGKMHMAERQWAE 798
LLE L+ + + + K LK LYQ+AL ++SA+PHP+IMGIIRECGGKMHM+E W E
Sbjct: 199 LLELYALEIQMYAETKNNKRLKALYQRALRVRSAVPHPKIMGIIRECGGKMHMSEENWEE 258
Query: 799 AATDFFEAFKNYDEAGNQRRIQCLRYLVLANMLMESEVNPFDGQEAKPYKNDPEILAMTN 978
A +DFFE+F+NYDEAG+ +RIQ L+YLVL MLM+S++NPF QE KPYK DP I AMT+
Sbjct: 259 AQSDFFESFRNYDEAGSMQRIQVLKYLVLTTMLMKSDINPFHSQETKPYKTDPRISAMTD 318
Query: 979 LVAAYQRNEIIEFEKILKNNRKTIMDDPFIRNYMEDLLKKVRTQVLLKLIKPYTKIGIPF 1158
LV A+QR++I +E++L N ++ DPFI ++++ + +RT+ +LKLI PYT+ + F
Sbjct: 319 LVDAFQRDDIHAYEEVLSKN-PDVLADPFIAENIDEVSRNMRTKAILKLIAPYTRFTLSF 377
Query: 1159 ISKELNVPEKDVTELLVSLILDSRIDGHIDEINRYLLRGDSANGRKLHKAVDKWNTQLKS 1338
ISK + + + ++L LILD +++ ID+ + ++ +++ +L ++V++WN L++
Sbjct: 378 ISKHIKISVTEAQDILSFLILDKKLNAKIDQESGTVVVESASDVERL-RSVEEWNESLRT 436
Query: 1339 L 1341
L
Sbjct: 437 L 437
>sp|Q7SI58|CSN2_NEUCR COP9 signalosome complex subunit 2 OS=Neurospora crassa
GN=csn-2 PE=1 SV=1
Length = 490
Score = 228 bits (580), Expect = 1e-058
Identities = 108/210 (51%), Positives = 155/210 (73%), Gaps = 2/210 (0%)
Frame = +1
Query: 625 LEFMPLKFRFTLKLR-QQKLKQLYQKALAIKSAIPHPRIMGIIRECGGKMHMAERQWAEA 801
LE L+ + + R +LK LYQKAL ++SA+PHP+I G+IRECGGKMHM+E W EA
Sbjct: 198 LEIYALEIQMYSETRNNNQLKVLYQKALKVRSAVPHPKIQGVIRECGGKMHMSEENWKEA 257
Query: 802 ATDFFEAFKNYDEAGNQRRIQCLRYLVLANMLMESEVNPFDGQEAKPYKNDPEILAMTNL 981
+DFFEAF+NYDEAG+ RRIQ L+YL+L MLM+S++NPFD QE KPY+NDP I AMT L
Sbjct: 258 QSDFFEAFRNYDEAGDLRRIQVLKYLLLTTMLMKSDINPFDSQEMKPYRNDPRIFAMTEL 317
Query: 982 VAAYQRNEIIEFEKILKNNRKTIMDDPFIRNYMEDLLKKVRTQVLLKLIKPYTKIGIPFI 1161
V AYQR++I +E +L+ N ++ DPFI ++++ + +RT+ ++KLI PYT++ I ++
Sbjct: 318 VDAYQRDDIYRYEDVLQKN-TDLLADPFIAENIDEVTRNMRTKGVVKLIAPYTRMRISWL 376
Query: 1162 SKELNVPEKDVTELLVSLILDSRIDGHIDE 1251
++ L + E +V ++L LI+D R+ G IDE
Sbjct: 377 AERLRITEPEVMDILSFLIVDGRVKGRIDE 406
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,366,676,449
Number of Sequences: 518415
Number of Extensions: 41366676449
Number of Successful Extensions: 294470065
Number of sequences better than 0.0: 0
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