BLASTX 7.6.2
Query= UN10373 /QuerySize=1117
(1116 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q7SXW4|TM111_DANRE Transmembrane protein 111 OS=Danio rerio G... 202 4e-051
sp|Q9P0I2|TM111_HUMAN Transmembrane protein 111 OS=Homo sapiens ... 202 4e-051
sp|Q99KI3|TM111_MOUSE Transmembrane protein 111 OS=Mus musculus ... 202 4e-051
sp|Q5R7C1|TM111_PONAB Transmembrane protein 111 OS=Pongo abelii ... 202 4e-051
sp|Q5U2V8|TM111_RAT Transmembrane protein 111 OS=Rattus norvegic... 202 4e-051
sp|Q3ZCB8|TM111_BOVIN Transmembrane protein 111 OS=Bos taurus GN... 202 5e-051
sp|Q9P787|YNY3_SCHPO UPF0347 membrane protein C1711.03 OS=Schizo... 167 2e-040
sp|Q54YN3|TM111_DICDI Transmembrane protein 111 homolog OS=Dicty... 156 3e-037
sp|B3LQQ2|EMC3_YEAS1 ER membrane protein complex subunit 3 OS=Sa... 107 1e-022
sp|B5VLV9|EMC3_YEAS6 ER membrane protein complex subunit 3 OS=Sa... 107 1e-022
sp|A7A082|EMC3_YEAS7 ER membrane protein complex subunit 3 OS=Sa... 106 5e-022
sp|P36039|EMC3_YEAST ER membrane protein complex subunit 3 OS=Sa... 106 5e-022
>sp|Q7SXW4|TM111_DANRE Transmembrane protein 111 OS=Danio rerio GN=tmem111 PE=2
SV=1
Length = 261
Score = 202 bits (513), Expect = 4e-051
Identities = 101/237 (42%), Positives = 152/237 (64%), Gaps = 7/237 (2%)
Frame = -3
Query: 1015 DLVLDTAIRDWVLIPLSVVMVLIGILRYLVSKLMRSSPSPDAKMVKEGQVIIRARNLKAA 836
+L+LD+ IR WV++P+ + L+G++R+ VS L++S + V + QV+IR+R L+
Sbjct: 5 ELLLDSNIRLWVVLPIVFITFLVGVIRHYVSILLQSDKKLTLEQVSDSQVLIRSRVLREN 64
Query: 835 ANFIPLRSFRTRRLYFSNEENGLLHVPKGQATNPQAQMFSDPNMAMDMMKKNLSMIIPQT 656
+IP +SF R+ YF+N+E+G K + P +DP+M DMMK N++ ++P
Sbjct: 65 GKYIPKQSFLMRKFYFNNQEDGFFKKTKRKVVPPSP--MTDPSMLTDMMKGNVTNVLPMI 122
Query: 655 LTFAWVNFFFSGFVAAKIPFPLTQRFRSMLQNGIDLSTVDVSYVSSRSWYFLNLFGLRGL 476
L W+N+ FSGFV K+PFPLT RF+ MLQ GI+L ++D S+VSS SWYFLN+FGLR +
Sbjct: 123 LIGGWINWTFSGFVTTKVPFPLTLRFKPMLQQGIELLSLDASWVSSASWYFLNVFGLRSM 182
Query: 475 FSLILGDENAIDDTQRMM-QMGGFGF----DASKSLGAEKDGLDIIQHDWALPRFEQ 320
+SLILG +N D ++ M QM G D +K+ AE + L++ H WAL E+
Sbjct: 183 YSLILGQDNGADQSRIMQEQMSGAAMAMPADTNKAFKAEWEALELTDHQWALENVEE 239
>sp|Q9P0I2|TM111_HUMAN Transmembrane protein 111 OS=Homo sapiens GN=TMEM111 PE=1
SV=3
Length = 261
Score = 202 bits (513), Expect = 4e-051
Identities = 102/237 (43%), Positives = 150/237 (63%), Gaps = 7/237 (2%)
Frame = -3
Query: 1015 DLVLDTAIRDWVLIPLSVVMVLIGILRYLVSKLMRSSPSPDAKMVKEGQVIIRARNLKAA 836
+L+LD+ IR WV++P+ ++ +G++R+ VS L++S + V + QV+IR+R L+
Sbjct: 5 ELLLDSNIRLWVVLPIVIITFFVGMIRHYVSILLQSDKKLTQEQVSDSQVLIRSRVLREN 64
Query: 835 ANFIPLRSFRTRRLYFSNEENGLLHVPKGQATNPQAQMFSDPNMAMDMMKKNLSMIIPQT 656
+IP +SF TR+ YF+N E+G K + P +DP M DMMK N++ ++P
Sbjct: 65 GKYIPKQSFLTRKYYFNNPEDGFFKKTKRKVVPPSP--MTDPTMLTDMMKGNVTNVLPMI 122
Query: 655 LTFAWVNFFFSGFVAAKIPFPLTQRFRSMLQNGIDLSTVDVSYVSSRSWYFLNLFGLRGL 476
L W+N FSGFV K+PFPLT RF+ MLQ GI+L T+D S+VSS SWYFLN+FGLR +
Sbjct: 123 LIGGWINMTFSGFVTTKVPFPLTLRFKPMLQQGIELLTLDASWVSSASWYFLNVFGLRSI 182
Query: 475 FSLILGDENAIDDTQRMM-QMGGFGF----DASKSLGAEKDGLDIIQHDWALPRFEQ 320
+SLILG +NA D ++ M QM G D +K+ E + L++ H WAL E+
Sbjct: 183 YSLILGQDNAADQSRMMQEQMTGAAMAMPADTNKAFKTEWEALELTDHQWALDDVEE 239
>sp|Q99KI3|TM111_MOUSE Transmembrane protein 111 OS=Mus musculus GN=Tmem111 PE=2
SV=3
Length = 261
Score = 202 bits (513), Expect = 4e-051
Identities = 102/237 (43%), Positives = 150/237 (63%), Gaps = 7/237 (2%)
Frame = -3
Query: 1015 DLVLDTAIRDWVLIPLSVVMVLIGILRYLVSKLMRSSPSPDAKMVKEGQVIIRARNLKAA 836
+L+LD+ IR WV++P+ ++ +G++R+ VS L++S + V + QV+IR+R L+
Sbjct: 5 ELLLDSNIRLWVVLPIVIITFFVGMIRHYVSILLQSDKKLTQEQVSDSQVLIRSRVLREN 64
Query: 835 ANFIPLRSFRTRRLYFSNEENGLLHVPKGQATNPQAQMFSDPNMAMDMMKKNLSMIIPQT 656
+IP +SF TR+ YF+N E+G K + P +DP M DMMK N++ ++P
Sbjct: 65 GKYIPKQSFLTRKYYFNNPEDGFFKKTKRKVVPPSP--MTDPTMLTDMMKGNVTNVLPMI 122
Query: 655 LTFAWVNFFFSGFVAAKIPFPLTQRFRSMLQNGIDLSTVDVSYVSSRSWYFLNLFGLRGL 476
L W+N FSGFV K+PFPLT RF+ MLQ GI+L T+D S+VSS SWYFLN+FGLR +
Sbjct: 123 LIGGWINMTFSGFVTTKVPFPLTLRFKPMLQQGIELLTLDASWVSSASWYFLNVFGLRSI 182
Query: 475 FSLILGDENAIDDTQRMM-QMGGFGF----DASKSLGAEKDGLDIIQHDWALPRFEQ 320
+SLILG +NA D ++ M QM G D +K+ E + L++ H WAL E+
Sbjct: 183 YSLILGQDNAADQSRMMQEQMTGAAMAMPADTNKAFKTEWEALELTDHQWALDDVEE 239
>sp|Q5R7C1|TM111_PONAB Transmembrane protein 111 OS=Pongo abelii GN=TMEM111 PE=2
SV=3
Length = 261
Score = 202 bits (513), Expect = 4e-051
Identities = 102/237 (43%), Positives = 150/237 (63%), Gaps = 7/237 (2%)
Frame = -3
Query: 1015 DLVLDTAIRDWVLIPLSVVMVLIGILRYLVSKLMRSSPSPDAKMVKEGQVIIRARNLKAA 836
+L+LD+ IR WV++P+ ++ +G++R+ VS L++S + V + QV+IR+R L+
Sbjct: 5 ELLLDSNIRLWVVLPIVIITFFVGMIRHYVSILLQSDKKLTQEQVSDSQVLIRSRVLREN 64
Query: 835 ANFIPLRSFRTRRLYFSNEENGLLHVPKGQATNPQAQMFSDPNMAMDMMKKNLSMIIPQT 656
+IP +SF TR+ YF+N E+G K + P +DP M DMMK N++ ++P
Sbjct: 65 GKYIPKQSFLTRKYYFNNPEDGFFKKTKRKVVPPSP--MTDPTMLTDMMKGNVTNVLPMI 122
Query: 655 LTFAWVNFFFSGFVAAKIPFPLTQRFRSMLQNGIDLSTVDVSYVSSRSWYFLNLFGLRGL 476
L W+N FSGFV K+PFPLT RF+ MLQ GI+L T+D S+VSS SWYFLN+FGLR +
Sbjct: 123 LIGGWINMTFSGFVTTKVPFPLTLRFKPMLQQGIELLTLDASWVSSASWYFLNVFGLRSI 182
Query: 475 FSLILGDENAIDDTQRMM-QMGGFGF----DASKSLGAEKDGLDIIQHDWALPRFEQ 320
+SLILG +NA D ++ M QM G D +K+ E + L++ H WAL E+
Sbjct: 183 YSLILGQDNAADQSRMMQEQMTGAAMAMPADTNKAFKTEWEALELTDHQWALDDVEE 239
>sp|Q5U2V8|TM111_RAT Transmembrane protein 111 OS=Rattus norvegicus GN=Tmem111
PE=2 SV=3
Length = 261
Score = 202 bits (513), Expect = 4e-051
Identities = 102/237 (43%), Positives = 150/237 (63%), Gaps = 7/237 (2%)
Frame = -3
Query: 1015 DLVLDTAIRDWVLIPLSVVMVLIGILRYLVSKLMRSSPSPDAKMVKEGQVIIRARNLKAA 836
+L+LD+ IR WV++P+ ++ +G++R+ VS L++S + V + QV+IR+R L+
Sbjct: 5 ELLLDSNIRLWVVLPIVIITFFVGMIRHYVSILLQSDKKLTQEQVSDSQVLIRSRVLREN 64
Query: 835 ANFIPLRSFRTRRLYFSNEENGLLHVPKGQATNPQAQMFSDPNMAMDMMKKNLSMIIPQT 656
+IP +SF TR+ YF+N E+G K + P +DP M DMMK N++ ++P
Sbjct: 65 GKYIPKQSFLTRKYYFNNPEDGFFKKTKRKVVPPSP--MTDPTMLTDMMKGNVTNVLPMI 122
Query: 655 LTFAWVNFFFSGFVAAKIPFPLTQRFRSMLQNGIDLSTVDVSYVSSRSWYFLNLFGLRGL 476
L W+N FSGFV K+PFPLT RF+ MLQ GI+L T+D S+VSS SWYFLN+FGLR +
Sbjct: 123 LIGGWINMTFSGFVTTKVPFPLTLRFKPMLQQGIELLTLDASWVSSASWYFLNVFGLRSI 182
Query: 475 FSLILGDENAIDDTQRMM-QMGGFGF----DASKSLGAEKDGLDIIQHDWALPRFEQ 320
+SLILG +NA D ++ M QM G D +K+ E + L++ H WAL E+
Sbjct: 183 YSLILGQDNAADQSRMMQEQMTGAAMAMPADTNKAFKTEWEALELTDHQWALDDVEE 239
>sp|Q3ZCB8|TM111_BOVIN Transmembrane protein 111 OS=Bos taurus GN=TMEM111 PE=2
SV=3
Length = 261
Score = 202 bits (512), Expect = 5e-051
Identities = 102/237 (43%), Positives = 150/237 (63%), Gaps = 7/237 (2%)
Frame = -3
Query: 1015 DLVLDTAIRDWVLIPLSVVMVLIGILRYLVSKLMRSSPSPDAKMVKEGQVIIRARNLKAA 836
+L+LD+ IR WV++P+ ++ +G++R+ VS L++S + V + QV+IR+R L+
Sbjct: 5 ELLLDSNIRLWVVLPIVIITFFVGMIRHYVSILLQSDKKLTQEQVSDSQVLIRSRVLREN 64
Query: 835 ANFIPLRSFRTRRLYFSNEENGLLHVPKGQATNPQAQMFSDPNMAMDMMKKNLSMIIPQT 656
+IP +SF TR+ YF+N E+G K + P +DP M DMMK N++ ++P
Sbjct: 65 GKYIPKQSFLTRKYYFNNPEDGFFKKTKRKVVPPSP--VTDPTMLTDMMKGNVTNVLPMI 122
Query: 655 LTFAWVNFFFSGFVAAKIPFPLTQRFRSMLQNGIDLSTVDVSYVSSRSWYFLNLFGLRGL 476
L W+N FSGFV K+PFPLT RF+ MLQ GI+L T+D S+VSS SWYFLN+FGLR +
Sbjct: 123 LIGGWINMTFSGFVTTKVPFPLTLRFKPMLQQGIELLTLDASWVSSASWYFLNVFGLRSI 182
Query: 475 FSLILGDENAIDDTQRMM-QMGGFGF----DASKSLGAEKDGLDIIQHDWALPRFEQ 320
+SLILG +NA D ++ M QM G D +K+ E + L++ H WAL E+
Sbjct: 183 YSLILGQDNAADQSRMMQEQMTGAAMAMPADTNKAFKTEWEALELTDHQWALDDVEE 239
>sp|Q9P787|YNY3_SCHPO UPF0347 membrane protein C1711.03 OS=Schizosaccharomyces
pombe GN=SPBC1711.03 PE=2 SV=1
Length = 258
Score = 167 bits (421), Expect = 2e-040
Identities = 93/254 (36%), Positives = 151/254 (59%), Gaps = 23/254 (9%)
Frame = -3
Query: 1018 EDLVLDTAIRDWVLIPLSVVMVLIGILRYLVSKLMRSSPSPDAK-MVKEGQVIIRARNLK 842
+ L+LD A+R+WVL+P+ VM+LIGILR+ + L++SSP +K ++E +++ RA L+
Sbjct: 2 QKLLLDPALRNWVLLPIMFVMILIGILRHNATILLQSSPKKLSKEEIREQRLLQRAYALR 61
Query: 841 AAANFIPLRSFRTRRLYFSNEENGLLHVPKGQATNPQAQMFSDPNM-------AMDMMKK 683
A +N + S R+ + ++ + +P A ++P M M+ MK
Sbjct: 62 ACSNSLLPESIEARKCFLIESLKSGKYL---KPVDPNAPKAANPLMDDKTLEGLMESMKG 118
Query: 682 NLSMIIPQTLTFAWVNFFFSGFVAAKIPFPLTQRFRSMLQNGIDLSTVDVSYVSSRSWYF 503
N+ M++PQT+ W+N FFSGF+ K+PFPLT RF+S+ Q+G+ +DV +VSS SWYF
Sbjct: 119 NMLMVVPQTIIMTWINEFFSGFILLKLPFPLTLRFKSIFQSGVATQDLDVQWVSSISWYF 178
Query: 502 LNLFGLRGLFSLILGDENAIDDTQRMMQMGGF------------GFDASKSLGAEKDGLD 359
LNLFGL+ +++L+LG+ NA + M M GF G D SK + +E + +
Sbjct: 179 LNLFGLKSVYALLLGENNAASNATNEMGMAGFSSAAATAQLIQPGQDISKMMLSEAENVQ 238
Query: 358 IIQHDWALPRFEQR 317
I++++ L E+R
Sbjct: 239 ILKNESLLVDVEKR 252
>sp|Q54YN3|TM111_DICDI Transmembrane protein 111 homolog OS=Dictyostelium
discoideum GN=tmem111 PE=3 SV=1
Length = 314
Score = 156 bits (394), Expect = 3e-037
Identities = 94/259 (36%), Positives = 145/259 (55%), Gaps = 20/259 (7%)
Frame = -3
Query: 1012 LVLDTAIRDWVLIPLSVVMVLIGILRYLVSKLMR--SSPSPDAKMVKEGQVIIRARNLKA 839
+VLD IR+WV+IP+ +V+ ++ L+ +S++M+ S D + + Q I R R L +
Sbjct: 6 IVLDVEIRNWVVIPILIVLFIVSALKLNISRIMQINSGKPQDVEKTMQMQTINRVRRLVS 65
Query: 838 AANFIPLRSFRTRRLYF-----SNEENGLLH--VPKGQATNPQ-----AQMFSDPNMAMD 695
N IP +SF R+ Y S G+L P + +NP MF+DP+ D
Sbjct: 66 FYNRIPQKSFFIRKAYLCGTTGSKTNKGILSSIAPTQEDSNPMNMMFANSMFTDPSGITD 125
Query: 694 MMKKNLSMIIPQTLTFAWVNFFFSGFVAAKIP-FPLTQRFRSMLQNGIDLSTVDVSYVSS 518
M+K N+ +IPQ +WVN FFSGFVA K+P FPLT RF++ LQ GI++ ++DVSYVSS
Sbjct: 126 MLKGNIMHLIPQVTMMSWVNHFFSGFVACKLPFFPLTIRFKTFLQRGIEMGSLDVSYVSS 185
Query: 517 RSWYFLNLFGLRGLFSLILGDENAIDDTQRMMQMGGFG-----FDASKSLGAEKDGLDII 353
SWYFL FG G+ +++LG+ D+Q + G K +EK+ +++I
Sbjct: 186 LSWYFLCWFGSEGINAILLGENMVSADSQLLQSSIEPGPPTQQTPIHKIYASEKENIEMI 245
Query: 352 QHDWALPRFEQRAESVLRK 296
++D + E R ++K
Sbjct: 246 RYDSLMTNIEDRFLDNIKK 264
>sp|B3LQQ2|EMC3_YEAS1 ER membrane protein complex subunit 3 OS=Saccharomyces
cerevisiae (strain RM11-1a) GN=AIM27 PE=3 SV=2
Length = 253
Score = 107 bits (267), Expect = 1e-022
Identities = 62/157 (39%), Positives = 90/157 (57%), Gaps = 21/157 (13%)
Frame = -3
Query: 751 GQATNPQAQMFSDPNMA---MDMMKKNLSMIIPQTLTFAWVNFFFSGFVAAKIPFPLTQR 581
G+ NP F+DPNM+ M+M K N++ IPQT+ WVN FF+GF+ ++PFPLT +
Sbjct: 100 GEVPNP----FNDPNMSNAMMNMAKGNMASFIPQTIIMWWVNHFFAGFILMQLPFPLTAK 155
Query: 580 FRSMLQNGIDLSTVDVSYVSSRSWYFLNLFGLRGLFSLILGDENAIDDTQRMMQMGGFG- 404
F+ MLQ GI +DV +VSS SWYF+++ GL +++LI ++D +Q G G
Sbjct: 156 FKEMLQTGIICQDLDVRWVSSISWYFISVLGLNPVYNLI-----GLNDQDMGIQAGIGGP 210
Query: 403 --------FDASKSLGAEKDGLDIIQHDWALPRFEQR 317
K++ A + L IIQH+ L EQR
Sbjct: 211 QGPQGPPQSQVDKAMHAMANDLTIIQHETCLDNVEQR 247
>sp|B5VLV9|EMC3_YEAS6 ER membrane protein complex subunit 3 OS=Saccharomyces
cerevisiae (strain AWRI1631) GN=AIM27 PE=3 SV=2
Length = 253
Score = 107 bits (267), Expect = 1e-022
Identities = 62/157 (39%), Positives = 90/157 (57%), Gaps = 21/157 (13%)
Frame = -3
Query: 751 GQATNPQAQMFSDPNMA---MDMMKKNLSMIIPQTLTFAWVNFFFSGFVAAKIPFPLTQR 581
G+ NP F+DPNM+ M+M K N++ IPQT+ WVN FF+GF+ ++PFPLT +
Sbjct: 100 GEVPNP----FNDPNMSNAMMNMAKGNMASFIPQTIIMWWVNHFFAGFILMQLPFPLTAK 155
Query: 580 FRSMLQNGIDLSTVDVSYVSSRSWYFLNLFGLRGLFSLILGDENAIDDTQRMMQMGGFG- 404
F+ MLQ GI +DV +VSS SWYF+++ GL +++LI ++D +Q G G
Sbjct: 156 FKEMLQTGIICQDLDVRWVSSISWYFISVLGLNPVYNLI-----GLNDQDMGIQAGIGGP 210
Query: 403 --------FDASKSLGAEKDGLDIIQHDWALPRFEQR 317
K++ A + L IIQH+ L EQR
Sbjct: 211 QGPQGPPQSQVDKAMHAMANDLTIIQHETCLDNVEQR 247
>sp|A7A082|EMC3_YEAS7 ER membrane protein complex subunit 3 OS=Saccharomyces
cerevisiae (strain YJM789) GN=AIM27 PE=3 SV=2
Length = 253
Score = 106 bits (262), Expect = 5e-022
Identities = 61/157 (38%), Positives = 90/157 (57%), Gaps = 21/157 (13%)
Frame = -3
Query: 751 GQATNPQAQMFSDPNMA---MDMMKKNLSMIIPQTLTFAWVNFFFSGFVAAKIPFPLTQR 581
G+ NP F+DP+M+ M+M K N++ IPQT+ WVN FF+GF+ ++PFPLT +
Sbjct: 100 GEVPNP----FNDPSMSNAMMNMAKGNMASFIPQTIIMWWVNHFFAGFILMQLPFPLTAK 155
Query: 580 FRSMLQNGIDLSTVDVSYVSSRSWYFLNLFGLRGLFSLILGDENAIDDTQRMMQMGGFG- 404
F+ MLQ GI +DV +VSS SWYF+++ GL +++LI ++D +Q G G
Sbjct: 156 FKEMLQTGIICQDLDVRWVSSISWYFISVLGLNPVYNLI-----GLNDQDMGIQAGIGGP 210
Query: 403 --------FDASKSLGAEKDGLDIIQHDWALPRFEQR 317
K++ A + L IIQH+ L EQR
Sbjct: 211 QGPQGPPQSQVDKAMHAMANDLTIIQHETCLDNVEQR 247
>sp|P36039|EMC3_YEAST ER membrane protein complex subunit 3 OS=Saccharomyces
cerevisiae GN=AIM27 PE=1 SV=3
Length = 253
Score = 106 bits (262), Expect = 5e-022
Identities = 61/157 (38%), Positives = 90/157 (57%), Gaps = 21/157 (13%)
Frame = -3
Query: 751 GQATNPQAQMFSDPNMA---MDMMKKNLSMIIPQTLTFAWVNFFFSGFVAAKIPFPLTQR 581
G+ NP F+DP+M+ M+M K N++ IPQT+ WVN FF+GF+ ++PFPLT +
Sbjct: 100 GEVPNP----FNDPSMSNAMMNMAKGNMASFIPQTIIMWWVNHFFAGFILMQLPFPLTAK 155
Query: 580 FRSMLQNGIDLSTVDVSYVSSRSWYFLNLFGLRGLFSLILGDENAIDDTQRMMQMGGFG- 404
F+ MLQ GI +DV +VSS SWYF+++ GL +++LI ++D +Q G G
Sbjct: 156 FKEMLQTGIICQDLDVRWVSSISWYFISVLGLNPVYNLI-----GLNDQDMGIQAGIGGP 210
Query: 403 --------FDASKSLGAEKDGLDIIQHDWALPRFEQR 317
K++ A + L IIQH+ L EQR
Sbjct: 211 QGPQGPPQSQVDKAMHAMANDLTIIQHETCLDNVEQR 247
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,893,998,746
Number of Sequences: 518415
Number of Extensions: 41893998746
Number of Successful Extensions: 306640000
Number of sequences better than 0.0: 0
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