BLASTX 7.6.2
Query= UN10387 /QuerySize=1316
(1315 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9LM02|SMT1_ARATH Cycloartenol-C-24-methyltransferase OS=Arab... 665 2e-190
sp|Q6ZIX2|SMT1_ORYSJ Cycloartenol-C-24-methyltransferase 1 OS=Or... 588 4e-167
sp|Q54I98|SMT1_DICDI Probable cycloartenol-C-24-methyltransferas... 350 2e-095
sp|Q759S7|ERG6_ASHGO Sterol 24-C-methyltransferase OS=Ashbya gos... 327 2e-088
sp|Q6CYB3|ERG6_KLULA Sterol 24-C-methyltransferase OS=Kluyveromy... 322 4e-087
sp|Q6BRB7|ERG6_DEBHA Sterol 24-C-methyltransferase OS=Debaryomyc... 319 3e-086
sp|O74198|ERG6_CANAL Sterol 24-C-methyltransferase OS=Candida al... 316 2e-085
sp|Q6FRZ7|ERG6_CANGA Sterol 24-C-methyltransferase OS=Candida gl... 312 6e-084
sp|Q875K1|ERG6_CLAL4 Sterol 24-C-methyltransferase OS=Clavispora... 310 2e-083
sp|P25087|ERG6_YEAST Sterol 24-C-methyltransferase OS=Saccharomy... 271 1e-071
sp|Q6C2D9|ERG6_YARLI Sterol 24-C-methyltransferase OS=Yarrowia l... 268 1e-070
sp|Q9P3R1|ERG6_NEUCR Sterol 24-C-methyltransferase OS=Neurospora... 264 1e-069
sp|O14321|ERG6_SCHPO Sterol 24-C-methyltransferase OS=Schizosacc... 258 6e-068
sp|Q39227|SMT2_ARATH 24-methylenesterol C-methyltransferase 2 OS... 251 1e-065
sp|Q96WX4|ERG6_PNECA Sterol 24-C-methyltransferase OS=Pneumocyst... 250 2e-065
sp|Q5EN22|ERG6_MAGGR Sterol 24-C-methyltransferase OS=Magnaporth... 244 1e-063
sp|Q94JS4|SMT3B_ARATH 24-methylenesterol C-methyltransferase 3 O... 234 2e-060
sp|O82427|SMT2_ORYSJ 24-methylenesterol C-methyltransferase 2 OS... 214 2e-054
>sp|Q9LM02|SMT1_ARATH Cycloartenol-C-24-methyltransferase OS=Arabidopsis
thaliana GN=SMT1 PE=2 SV=1
Length = 336
Score = 665 bits (1715), Expect = 2e-190
Identities = 316/336 (94%), Positives = 330/336 (98%)
Frame = +2
Query: 104 MDLASNLGGKIDKSDVLSAVERYEQYHVFHGGDEEERKANYTDMVNEYYDLATSFYEYGW 283
MDLASNLGGKIDKSDVL+AVE+YEQYHVFHGG+EEERKANYTDMVN+YYDLATSFYEYGW
Sbjct: 1 MDLASNLGGKIDKSDVLTAVEKYEQYHVFHGGNEEERKANYTDMVNKYYDLATSFYEYGW 60
Query: 284 GESFHFAHRWNGESLRESIKRHEHFLALQLGVKPGQKVLDVGCGIGGPLREIARFSNSSV 463
GESFHFA RW GESLRESIKRHEHFLALQLG++PGQKVLDVGCGIGGPLREIARFSNS V
Sbjct: 61 GESFHFAQRWKGESLRESIKRHEHFLALQLGIQPGQKVLDVGCGIGGPLREIARFSNSVV 120
Query: 464 TGINNNEYQITRGKELNRLAGVDKTCGFVKADFMKMPFPENTFDAVYAIEATCHAPDAYG 643
TG+NNNEYQITRGKELNRLAGVDKTC FVKADFMKMPFPEN+FDAVYAIEATCHAPDAYG
Sbjct: 121 TGLNNNEYQITRGKELNRLAGVDKTCNFVKADFMKMPFPENSFDAVYAIEATCHAPDAYG 180
Query: 644 CYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAQHQKIKAEIEIGDGLPDIRLTSKCLEALK 823
CYKEIYRVLKPGQCFAAYEWCMTDAFDPDNA+HQKIK EIEIGDGLPDIRLT+KCLEALK
Sbjct: 181 CYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAEHQKIKGEIEIGDGLPDIRLTTKCLEALK 240
Query: 824 QAGFEVIWEKDLAKDSPVPWYLPLDKNHFSLSSFRLTAVGRSITKNMVKLLEYIRLAPKG 1003
QAGFEVIWEKDLAKDSPVPWYLPLDKNHFSLSSFRLTAVGR ITKNMVK+LEYIRLAP+G
Sbjct: 241 QAGFEVIWEKDLAKDSPVPWYLPLDKNHFSLSSFRLTAVGRFITKNMVKILEYIRLAPQG 300
Query: 1004 SQRVSDFLEKAAEGLVDGGRREIFTPMYFFLARKPE 1111
SQRVS+FLE+AAEGLVDGGRREIFTPMYFFLARKPE
Sbjct: 301 SQRVSNFLEQAAEGLVDGGRREIFTPMYFFLARKPE 336
>sp|Q6ZIX2|SMT1_ORYSJ Cycloartenol-C-24-methyltransferase 1 OS=Oryza sativa
subsp. japonica GN=Smt1-1 PE=2 SV=1
Length = 344
Score = 588 bits (1514), Expect = 4e-167
Identities = 275/341 (80%), Positives = 310/341 (90%)
Frame = +2
Query: 86 MSKSGAMDLASNLGGKIDKSDVLSAVERYEQYHVFHGGDEEERKANYTDMVNEYYDLATS 265
MS+SGAMDLAS LGGKI K +V SAV+ YE+YH ++GG EE RK+NYTDMVN+YYDLATS
Sbjct: 1 MSRSGAMDLASGLGGKITKDEVKSAVDEYEKYHGYYGGKEEARKSNYTDMVNKYYDLATS 60
Query: 266 FYEYGWGESFHFAHRWNGESLRESIKRHEHFLALQLGVKPGQKVLDVGCGIGGPLREIAR 445
FYEYGWGESFHFAHRWNGESLRESIKRHEHFLALQLGVKPG KVLDVGCGIGGPLREIA+
Sbjct: 61 FYEYGWGESFHFAHRWNGESLRESIKRHEHFLALQLGVKPGMKVLDVGCGIGGPLREIAK 120
Query: 446 FSNSSVTGINNNEYQITRGKELNRLAGVDKTCGFVKADFMKMPFPENTFDAVYAIEATCH 625
FS +SVTG+NNNEYQITRGKELNR+AGV TC FVKADFMKMPF +NTFDAVYAIEATCH
Sbjct: 121 FSLASVTGLNNNEYQITRGKELNRVAGVSGTCDFVKADFMKMPFSDNTFDAVYAIEATCH 180
Query: 626 APDAYGCYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAQHQKIKAEIEIGDGLPDIRLTSK 805
APD GCYKEIYRVLKPGQCFA YEWC+TD ++P+NA H++IK EIE+G+GLPDIR T +
Sbjct: 181 APDPVGCYKEIYRVLKPGQCFAVYEWCITDHYEPNNATHKRIKDEIELGNGLPDIRSTQQ 240
Query: 806 CLEALKQAGFEVIWEKDLAKDSPVPWYLPLDKNHFSLSSFRLTAVGRSITKNMVKLLEYI 985
CL+A K AGFEVIW+KDLA+DSPVPWYLPLD + FSLSSFRLT VGR+IT+ MVK LEY+
Sbjct: 241 CLQAAKDAGFEVIWDKDLAEDSPVPWYLPLDPSRFSLSSFRLTTVGRAITRTMVKALEYV 300
Query: 986 RLAPKGSQRVSDFLEKAAEGLVDGGRREIFTPMYFFLARKP 1108
LAP+GS+RVS+FLEKAAEGLV+GG++EIFTPMYFFL RKP
Sbjct: 301 GLAPQGSERVSNFLEKAAEGLVEGGKKEIFTPMYFFLVRKP 341
>sp|Q54I98|SMT1_DICDI Probable cycloartenol-C-24-methyltransferase 1
OS=Dictyostelium discoideum GN=smt1 PE=1 SV=1
Length = 354
Score = 350 bits (896), Expect = 2e-095
Identities = 166/311 (53%), Positives = 218/311 (70%), Gaps = 4/311 (1%)
Frame = +2
Query: 185 VFHGGDE---EERKANYTDMVNEYYDLATSFYEYGWGESFHFAHRWNGESLRESIKRHEH 355
+F G D+ + RK NYT MVN +YDLAT FYE+GWG+SFHFA R ES SI RHE
Sbjct: 42 LFKGNDDKAIQARKNNYTHMVNTFYDLATDFYEFGWGQSFHFATRHKYESFEASIARHEM 101
Query: 356 FLALQLGVKPGQKVLDVGCGIGGPLREIARFSNSSVTGINNNEYQITRGKELNRLAGVDK 535
++A QLG+ PG KV+D+GCG+GGP+R IARFS ++V G+NNNEYQI RGK LN AG+
Sbjct: 102 YMAHQLGLFPGMKVIDIGCGVGGPMRTIARFSGANVVGLNNNEYQIQRGKRLNESAGLSH 161
Query: 536 TCGFVKADFMKMPFPENTFDAVYAIEATCHAPDAYGCYKEIYRVLKPGQCFAAYEWCMTD 715
C F+KADFM +P +NT+D Y IEATCHAPD G YKE++R++KPG F YEW MT+
Sbjct: 162 LCSFIKADFMHVPVEDNTYDCAYQIEATCHAPDLVGLYKEVFRIVKPGGLFGGYEWIMTN 221
Query: 716 AFDPDNAQHQKIKAEIEIGDGLPDIRLTSKCLEALKQAGFEVIWEKDLAKDSPVPWYLPL 895
F+P++ IK +IE+G+GLPD+ ++ + A K AGFEVI D+A+ S +PWYLPL
Sbjct: 222 KFNPEDPVEVNIKKQIELGNGLPDLVKPAEIINAAKAAGFEVITAFDVAETSELPWYLPL 281
Query: 896 DKNHFSLSSFRLTAVGRSITKNMVKLLEYIRLAPKGSQRVSDFLEKAAEGLVDGGRREIF 1075
S++ F T VGR +T +LLE ++LAP GS + +L+ AA LV GG ++IF
Sbjct: 282 SSG-VSITGFLHTGVGRYLTGKFTQLLEIVKLAPAGSYNTNVWLQNAATFLVQGGEKQIF 340
Query: 1076 TPMYFFLARKP 1108
+PM+F L RKP
Sbjct: 341 SPMFFLLCRKP 351
>sp|Q759S7|ERG6_ASHGO Sterol 24-C-methyltransferase OS=Ashbya gossypii GN=ERG6
PE=3 SV=1
Length = 373
Score = 327 bits (836), Expect = 2e-088
Identities = 160/311 (51%), Positives = 208/311 (66%), Gaps = 8/311 (2%)
Frame = +2
Query: 203 EEERKANYTDMVNEYYDLATSFYEYGWGESFHFAHRWNGESLRESIKRHEHFLALQLGVK 382
EE R A+Y + + YY++ T FYEYGWG SFHF+ + GES S+ RHEH+LA + G+
Sbjct: 60 EERRLADYNESTHSYYNVVTDFYEYGWGASFHFSRFYTGESFAMSMARHEHYLAHRAGIT 119
Query: 383 PGQKVLDVGCGIGGPLREIARFSNSSVTGINNNEYQITRGKELNRLAGVDKTCGFVKADF 562
G VLDVGCG+GGP REIARF+ V G+NNN+YQI +GK +R G+ +VK DF
Sbjct: 120 SGDLVLDVGCGVGGPAREIARFTGCRVVGLNNNDYQIMKGKHYSRKLGLGDQVSYVKGDF 179
Query: 563 MKMPFPENTFDAVYAIEATCHAPDAYGCYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAQH 742
M M FP+ TFD VYAIEATCHAP G Y EIYRVLKPG FA YEW MT+ +D N +H
Sbjct: 180 MNMDFPDATFDKVYAIEATCHAPSFEGVYGEIYRVLKPGGVFAVYEWVMTENYDETNPEH 239
Query: 743 QKIKAEIEIGDGLPDIRLTSKCLEALKQAGFEVIWEKDLA-KDSPVPWYLPLD------K 901
++I +IE+GDG+P + +AL + GFE++ ++D A D PVPWY PL +
Sbjct: 240 RRIAYDIELGDGIPKMYSVKVARDALAKVGFEILVDEDRADNDDPVPWYYPLTGEWAYIQ 299
Query: 902 NHFSLSSF-RLTAVGRSITKNMVKLLEYIRLAPKGSQRVSDFLEKAAEGLVDGGRREIFT 1078
L +F R +A+GR +T V L+E +RLAP+GS V + LE AA GLV GG+ ++FT
Sbjct: 300 TIADLGTFVRTSALGRRVTSAFVSLMETLRLAPRGSSEVVNALESAAAGLVAGGKSKLFT 359
Query: 1079 PMYFFLARKPE 1111
PM F+ARKPE
Sbjct: 360 PMMLFVARKPE 370
>sp|Q6CYB3|ERG6_KLULA Sterol 24-C-methyltransferase OS=Kluyveromyces lactis
GN=ERG6 PE=3 SV=1
Length = 371
Score = 322 bits (824), Expect = 4e-087
Identities = 165/355 (46%), Positives = 224/355 (63%), Gaps = 15/355 (4%)
Frame = +2
Query: 77 GFTMSKSGAMDLASNLGGKIDKSDVLSAVERYEQYHVFHGGDEEERK--ANYTDMVNEYY 250
G ++KSG L S +KS AV +Y ++ + ER+ +Y + + YY
Sbjct: 20 GNNVTKSGFSALVSK-----NKSAQTEAVAKYLKHWDGKTDADAERRRLEDYNESTHSYY 74
Query: 251 DLATSFYEYGWGESFHFAHRWNGESLRESIKRHEHFLALQLGVKPGQKVLDVGCGIGGPL 430
++ T FYEYGWG SFHF+ + GES S+ RHEH+LA + G+K +LDVGCG+GGP
Sbjct: 75 NVVTDFYEYGWGSSFHFSRFFKGESFSASVARHEHYLAYKAGIKENDLILDVGCGVGGPA 134
Query: 431 REIARFSNSSVTGINNNEYQITRGKELNRLAGVDKTCGFVKADFMKMPFPENTFDAVYAI 610
R I+RF+ ++ G+NNN+YQI + + +D FVK DFMKM F ENTFD+VYAI
Sbjct: 135 RTISRFTGCNIIGLNNNDYQIQKANYYAKRDHLDSKLSFVKGDFMKMEFDENTFDSVYAI 194
Query: 611 EATCHAPDAYGCYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAQHQKIKAEIEIGDGLPDI 790
EATCHAP G Y EIY+VLKPG FA YEW MTD +D N +H+KI EIE+GDG+P +
Sbjct: 195 EATCHAPTFEGVYGEIYKVLKPGGTFAVYEWVMTDKYDETNPEHRKIAYEIELGDGIPKM 254
Query: 791 RLTSKCLEALKQAGFEVIWEKDLA-KDSPVPWYLPLDKNHFSLSS-------FRLTAVGR 946
+AL + GFE++ E DLA D +PWY PL ++S FR + +GR
Sbjct: 255 YSVDAARDALSKVGFEILEENDLADNDDEIPWYAPLTGEWKYVNSVADLATFFRTSRLGR 314
Query: 947 SITKNMVKLLEYIRLAPKGSQRVSDFLEKAAEGLVDGGRREIFTPMYFFLARKPE 1111
+ T +MV + E + LAPKGS V++ LE+AA GLV GG +++FTPM F+A+KPE
Sbjct: 315 AFTTSMVTVFEKLGLAPKGSVSVTNALEEAAVGLVAGGEKKLFTPMMLFVAKKPE 369
>sp|Q6BRB7|ERG6_DEBHA Sterol 24-C-methyltransferase OS=Debaryomyces hansenii
GN=ERG6 PE=3 SV=1
Length = 377
Score = 319 bits (817), Expect = 3e-086
Identities = 155/313 (49%), Positives = 211/313 (67%), Gaps = 12/313 (3%)
Frame = +2
Query: 200 DEEERKANYTDMVNEYYDLATSFYEYGWGESFHFAHRWNGESLRESIKRHEHFLALQLGV 379
DE++R ++Y+++ YY+L T FYEYGWG SFHF+ + GE+ R++ RHEHFLA ++ +
Sbjct: 62 DEDKRLSDYSNLTAHYYNLVTDFYEYGWGSSFHFSRYYTGEAFRQATARHEHFLAHKMQI 121
Query: 380 KPGQKVLDVGCGIGGPLREIARFSNSSVTGINNNEYQITRGKELNRLAGVDKTCGFVKAD 559
KVLDVGCG+GGP REI RF++ S+ G+NNN+YQI R R +D FVK D
Sbjct: 122 NENMKVLDVGCGVGGPAREICRFTDCSIVGLNNNDYQIERANHYARKYKLDDKLSFVKGD 181
Query: 560 FMKMPFPENTFDAVYAIEATCHAPDAYGCYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAQ 739
FM+M F +FDAVYAIEAT HAP G Y EIY+VLKPG F YEW MTD +D +N +
Sbjct: 182 FMQMDFEAESFDAVYAIEATVHAPVLEGVYSEIYKVLKPGGVFGVYEWVMTDKYDDENEE 241
Query: 740 HQKIKAEIEIGDGLPDIRLTSKCLEALKQAGFEVIWEKDLA-KDSPVPWYLPLD------ 898
H+KI IE+GDG+P + +ALK GFE+ +E DLA K+ +PWY PL
Sbjct: 242 HRKIAYGIEVGDGIPKMYKREVAEKALKSVGFEIEYEADLADKEDDIPWYYPLSGEWKYV 301
Query: 899 ---KNHFSLSSFRLTAVGRSITKNMVKLLEYIRLAPKGSQRVSDFLEKAAEGLVDGGRRE 1069
++F++ FR + VGR+IT V L+E + LAPKGS++V++ LE AA LV+GGR++
Sbjct: 302 QTLSDYFTI--FRTSKVGRTITTEAVGLMEKLGLAPKGSKQVTNALEDAAVNLVEGGRQK 359
Query: 1070 IFTPMYFFLARKP 1108
+FTPM ++ RKP
Sbjct: 360 LFTPMMLYVCRKP 372
>sp|O74198|ERG6_CANAL Sterol 24-C-methyltransferase OS=Candida albicans GN=ERG6
PE=3 SV=1
Length = 376
Score = 316 bits (809), Expect = 2e-085
Identities = 163/355 (45%), Positives = 220/355 (61%), Gaps = 12/355 (3%)
Frame = +2
Query: 80 FTMSKSGAMDLASNLGGKIDKSDVLSAVERYEQYHVFHGG----DEEERKANYTDMVNEY 247
FT + G + L I KS ++V + + GG DEE+R +Y+ + + Y
Sbjct: 17 FTKALHGESYKKTGLSALIAKSKDAASVAAEGYFKHWDGGISKDDEEKRLNDYSQLTHHY 76
Query: 248 YDLATSFYEYGWGESFHFAHRWNGESLRESIKRHEHFLALQLGVKPGQKVLDVGCGIGGP 427
Y+L T FYEYGWG SFHF+ + GE+ R++ RHEHFLA ++ + KVLDVGCG+GGP
Sbjct: 77 YNLVTDFYEYGWGSSFHFSRYYKGEAFRQATARHEHFLAHKMNLNENMKVLDVGCGVGGP 136
Query: 428 LREIARFSNSSVTGINNNEYQITRGKELNRLAGVDKTCGFVKADFMKMPFPENTFDAVYA 607
REI RF++ + G+NNN+YQI R + +D +VK DFM+M F +FDAVYA
Sbjct: 137 GREITRFTDCEIVGLNNNDYQIERANHYAKKYHLDHKLSYVKGDFMQMDFEPESFDAVYA 196
Query: 608 IEATCHAPDAYGCYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAQHQKIKAEIEIGDGLPD 787
IEAT HAP G Y EIY+VLKPG F YEW MTD +D N +H+KI IE+GDG+P
Sbjct: 197 IEATVHAPVLEGVYSEIYKVLKPGGIFGVYEWVMTDKYDETNEEHRKIAYGIEVGDGIPK 256
Query: 788 IRLTSKCLEALKQAGFEVIWEKDLAK-DSPVPWYLPLDKN-------HFSLSSFRLTAVG 943
+ +ALK GFE+ ++KDLA D +PWY PL + L+ FR + +G
Sbjct: 257 MYSRKVAEQALKNVGFEIEYQKDLADVDDEIPWYYPLSGDLKFCQTFGDYLTVFRTSRIG 316
Query: 944 RSITKNMVKLLEYIRLAPKGSQRVSDFLEKAAEGLVDGGRREIFTPMYFFLARKP 1108
R IT V L+E I LAPKGS++V+ LE AA LV+GGR+++FTPM ++ RKP
Sbjct: 317 RFITTESVGLMEKIGLAPKGSKQVTHALEDAAVNLVEGGRQKLFTPMMLYVVRKP 371
>sp|Q6FRZ7|ERG6_CANGA Sterol 24-C-methyltransferase OS=Candida glabrata GN=ERG6
PE=3 SV=1
Length = 372
Score = 312 bits (797), Expect = 6e-084
Identities = 154/311 (49%), Positives = 204/311 (65%), Gaps = 8/311 (2%)
Frame = +2
Query: 203 EEERKANYTDMVNEYYDLATSFYEYGWGESFHFAHRWNGESLRESIKRHEHFLALQLGVK 382
E+ R +Y + + YY++ T FYEYGWG SFHF+ + GE+ + ++ RHE +LA G+K
Sbjct: 59 EDRRLEDYNEATHSYYNVVTDFYEYGWGSSFHFSRFYKGENFQAAMARHEQYLAYMAGIK 118
Query: 383 PGQKVLDVGCGIGGPLREIARFSNSSVTGINNNEYQITRGKELNRLAGVDKTCGFVKADF 562
G VLDVGCG+GGP R IARF+ ++ G+NNN+YQI + K + + FVK DF
Sbjct: 119 KGDLVLDVGCGVGGPARTIARFTGCNIIGLNNNDYQIQKAKYYAKKYNLQDHMDFVKGDF 178
Query: 563 MKMPFPENTFDAVYAIEATCHAPDAYGCYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAQH 742
M M F N+FD VYAIEATCHAP G Y EIY+VLKPG FA YEW MT+ +D +N +H
Sbjct: 179 MNMEFEPNSFDKVYAIEATCHAPKLEGVYGEIYKVLKPGGTFAVYEWVMTENYDENNEEH 238
Query: 743 QKIKAEIEIGDGLPDIRLTSKCLEALKQAGFEVIWEKDLA-KDSPVPWYLPLD---KNHF 910
+KI EIE+GDG+P + +ALK GFEV KDLA +D +PWY PL K
Sbjct: 239 RKIAYEIELGDGIPKMFTVDVAKQALKNVGFEVEVSKDLADEDDEIPWYYPLTGEWKYVQ 298
Query: 911 SLSS----FRLTAVGRSITKNMVKLLEYIRLAPKGSQRVSDFLEKAAEGLVDGGRREIFT 1078
SLS FR + GR T MV ++E + +AP+GS V+ LE AA GLV+GGR+++FT
Sbjct: 299 SLSDIATFFRTSYFGRKFTNCMVSIMEKVGVAPQGSVEVTAALENAAVGLVEGGRKKLFT 358
Query: 1079 PMYFFLARKPE 1111
PM+ F+A+KPE
Sbjct: 359 PMFLFVAKKPE 369
>sp|Q875K1|ERG6_CLAL4 Sterol 24-C-methyltransferase OS=Clavispora lusitaniae
(strain ATCC 42720) GN=ERG6 PE=3 SV=1
Length = 375
Score = 310 bits (793), Expect = 2e-083
Identities = 151/311 (48%), Positives = 209/311 (67%), Gaps = 8/311 (2%)
Frame = +2
Query: 200 DEEERKANYTDMVNEYYDLATSFYEYGWGESFHFAHRWNGESLRESIKRHEHFLALQLGV 379
DE++R +Y+ + YY+L T FYEYGWG SFHF+ + GE+ R++ RHEHFLA ++ +
Sbjct: 61 DEKKRLDDYSSLTKNYYNLVTDFYEYGWGSSFHFSRYYKGEAFRQATARHEHFLAHKMNI 120
Query: 380 KPGQKVLDVGCGIGGPLREIARFSNSSVTGINNNEYQITRGKELNRLAGVDKTCGFVKAD 559
+VLDVGCG+GGP REI RF++ ++ G+NNN+YQ+ R + + +D +VK D
Sbjct: 121 NENMRVLDVGCGVGGPGREICRFTDCTIVGLNNNDYQVERAQYYAKKYKLDDKLSYVKGD 180
Query: 560 FMKMPFPENTFDAVYAIEATCHAPDAYGCYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAQ 739
FM+M F +FDAVYAIEAT HAP G Y EIY+VLKPG F YEW MTD +D +N +
Sbjct: 181 FMQMDFEPESFDAVYAIEATVHAPVLEGVYSEIYKVLKPGGVFGVYEWVMTDKYDENNEE 240
Query: 740 HQKIKAEIEIGDGLPDIRLTSKCLEALKQAGFEVIWEKDLAK-DSPVPWYLPLD---KNH 907
H+KI IE+GDG+P + +ALK GF++ +EKDLA + +PWY PL K
Sbjct: 241 HRKIAYGIEVGDGIPKMYKREVAEQALKNVGFDIEYEKDLADVNDEIPWYYPLAGEWKYV 300
Query: 908 FSLSS----FRLTAVGRSITKNMVKLLEYIRLAPKGSQRVSDFLEKAAEGLVDGGRREIF 1075
+LS FR + +GR++T N+V L+E I LAPKGS++V+ LE AA LV GG +++F
Sbjct: 301 QTLSDCFTIFRTSKIGRTVTTNVVGLMEKIGLAPKGSKQVTGALEDAAVNLVAGGEQKLF 360
Query: 1076 TPMYFFLARKP 1108
TPM ++ARKP
Sbjct: 361 TPMMLYIARKP 371
>sp|P25087|ERG6_YEAST Sterol 24-C-methyltransferase OS=Saccharomyces cerevisiae
GN=ERG6 PE=1 SV=4
Length = 383
Score = 271 bits (691), Expect = 1e-071
Identities = 127/232 (54%), Positives = 158/232 (68%), Gaps = 1/232 (0%)
Frame = +2
Query: 203 EEERKANYTDMVNEYYDLATSFYEYGWGESFHFAHRWNGESLRESIKRHEHFLALQLGVK 382
EE R +Y + + YY++ T FYEYGWG SFHF+ + GES SI RHEH+LA + G++
Sbjct: 59 EERRLEDYNEATHSYYNVVTDFYEYGWGSSFHFSRFYKGESFAASIARHEHYLAYKAGIQ 118
Query: 383 PGQKVLDVGCGIGGPLREIARFSNSSVTGINNNEYQITRGKELNRLAGVDKTCGFVKADF 562
G VLDVGCG+GGP REIARF+ +V G+NNN+YQI + K + + FVK DF
Sbjct: 119 RGDLVLDVGCGVGGPAREIARFTGCNVIGLNNNDYQIAKAKYYAKKYNLSDQMDFVKGDF 178
Query: 563 MKMPFPENTFDAVYAIEATCHAPDAYGCYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAQH 742
MKM F ENTFD VYAIEATCHAP G Y EIY+VLKPG FA YEW MTD +D +N +H
Sbjct: 179 MKMDFEENTFDKVYAIEATCHAPKLEGVYSEIYKVLKPGGTFAVYEWVMTDKYDENNPEH 238
Query: 743 QKIKAEIEIGDGLPDIRLTSKCLEALKQAGFEVIWEKDLA-KDSPVPWYLPL 895
+KI EIE+GDG+P + +ALK GFEV+ +DLA D +PWY PL
Sbjct: 239 RKIAYEIELGDGIPKMFHVDVARKALKNCGFEVLVSEDLADNDDEIPWYYPL 290
>sp|Q6C2D9|ERG6_YARLI Sterol 24-C-methyltransferase OS=Yarrowia lipolytica
GN=ERG6 PE=3 SV=1
Length = 381
Score = 268 bits (683), Expect = 1e-070
Identities = 120/233 (51%), Positives = 163/233 (69%), Gaps = 1/233 (0%)
Frame = +2
Query: 200 DEEERKANYTDMVNEYYDLATSFYEYGWGESFHFAHRWNGESLRESIKRHEHFLALQLGV 379
DE+ R +Y + YY+L T FYEYGWG SFHF+ + GE+ R++ RHEH+LA ++G+
Sbjct: 67 DEQGRIEDYAGLTKHYYNLVTDFYEYGWGSSFHFSRYYKGEAFRQATARHEHYLAYKMGI 126
Query: 380 KPGQKVLDVGCGIGGPLREIARFSNSSVTGINNNEYQITRGKELNRLAGVDKTCGFVKAD 559
+PG KVLDVGCG+GGP REIARF+ +++ G+NNN+YQ+ RG + + G +VK D
Sbjct: 127 QPGMKVLDVGCGVGGPAREIARFTGANIVGLNNNDYQVERGTHYSEVQGFGDQVTYVKGD 186
Query: 560 FMKMPFPENTFDAVYAIEATCHAPDAYGCYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAQ 739
FM+M FP+N+FDAVYAIEAT HAP G Y EI+RVLKPG F YEW MTD +D N +
Sbjct: 187 FMQMDFPDNSFDAVYAIEATVHAPVLEGVYSEIFRVLKPGGVFGVYEWVMTDEYDESNPE 246
Query: 740 HQKIKAEIEIGDGLPDIRLTSKCLEALKQAGFEVIWEKDL-AKDSPVPWYLPL 895
H+ I IE GDG+P + ++AL+ GF++ +++DL A D+ VPWY PL
Sbjct: 247 HRDICYGIEKGDGIPKMYKREVAVKALENVGFDIEYQEDLAADDAEVPWYYPL 299
>sp|Q9P3R1|ERG6_NEUCR Sterol 24-C-methyltransferase OS=Neurospora crassa
GN=B24P7.240 PE=3 SV=1
Length = 379
Score = 264 bits (673), Expect = 1e-069
Identities = 122/233 (52%), Positives = 160/233 (68%), Gaps = 1/233 (0%)
Frame = +2
Query: 200 DEEERKANYTDMVNEYYDLATSFYEYGWGESFHFAHRWNGESLRESIKRHEHFLALQLGV 379
D E R Y + YY+LAT YEYGWG+ FHF GES ++I RHEH+LA Q+G+
Sbjct: 67 DREARTKEYATLTRHYYNLATDIYEYGWGQCFHFCRYSPGESFYQAIARHEHYLAAQIGI 126
Query: 380 KPGQKVLDVGCGIGGPLREIARFSNSSVTGINNNEYQITRGKELNRLAGVDKTCGFVKAD 559
K KVLDVGCG+GGP REIA+F+++ +TG+NNN+YQI R G+ FVK D
Sbjct: 127 KKDMKVLDVGCGVGGPAREIAKFTDAHITGLNNNDYQIDRATHYAVRDGLSGQLKFVKGD 186
Query: 560 FMKMPFPENTFDAVYAIEATCHAPDAYGCYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAQ 739
FM+M FP+N+FDAVYAIEAT HAP G Y EIYRVLKPG F YEW MTD +D DN +
Sbjct: 187 FMQMSFPDNSFDAVYAIEATVHAPKLEGVYGEIYRVLKPGGTFGVYEWLMTDNYDNDNVE 246
Query: 740 HQKIKAEIEIGDGLPDIRLTSKCLEALKQAGFEVIWEKDLA-KDSPVPWYLPL 895
H+ I+ IE+G+G+ ++ S+ L A+K GFE++ +DLA ++ P+PWY P+
Sbjct: 247 HRDIRLAIEVGNGISNMVTISEGLAAMKNVGFELVHHEDLADRNDPMPWYWPI 299
>sp|O14321|ERG6_SCHPO Sterol 24-C-methyltransferase OS=Schizosaccharomyces pombe
GN=SPBC16E9.05 PE=2 SV=1
Length = 378
Score = 258 bits (659), Expect = 6e-068
Identities = 125/250 (50%), Positives = 165/250 (66%), Gaps = 6/250 (2%)
Frame = +2
Query: 164 ERYEQYHVFHGGDEEERKA----NYTDMVNEYYDLATSFYEYGWGESFHFAHRWNGESLR 331
E +E + H + EE +A Y +VN YYDLAT YEYGW +SFHF+ + GE+
Sbjct: 47 EYFEFWDRNHENESEEDRARRIDGYKSVVNSYYDLATDLYEYGWSQSFHFSRFYKGEAFA 106
Query: 332 ESIKRHEHFLALQLGVKPGQKVLDVGCGIGGPLREIARFSNSSVTGINNNEYQITRGKEL 511
+SI RHEH+LA ++G+KPG +VLDVGCG+GGP REI F+ ++ G+NNN+YQI+R
Sbjct: 107 QSIARHEHYLAYRMGIKPGSRVLDVGCGVGGPAREITEFTGCNLVGLNNNDYQISRCNNY 166
Query: 512 NRLAGVDKTCGFVKADFMKMPFPENTFDAVYAIEATCHAPDAYGCYKEIYRVLKPGQCFA 691
+DK FVK DFM MPF +NTFD VYAIEAT HAP G Y EI+RVLKPG F
Sbjct: 167 AVKRNLDKKQVFVKGDFMHMPFEDNTFDYVYAIEATVHAPSLEGVYGEIFRVLKPGGVFG 226
Query: 692 AYEWCMTDAFDPDNAQHQKIKAEIEIGDGLPDIRLTSKCLEALKQAGFEVIWEKDLA-KD 868
YEW M+D +D +H++I IE+GDG+P + +EA+K+ GF ++ E DL D
Sbjct: 227 VYEWVMSDDYDSSIPKHREIAYNIEVGDGIPQMVRKCDAVEAIKKVGFNLLEEDDLTDHD 286
Query: 869 SP-VPWYLPL 895
+P +PWY PL
Sbjct: 287 NPDLPWYYPL 296
>sp|Q39227|SMT2_ARATH 24-methylenesterol C-methyltransferase 2 OS=Arabidopsis
thaliana GN=SMT2 PE=1 SV=2
Length = 361
Score = 251 bits (640), Expect = 1e-065
Identities = 137/348 (39%), Positives = 195/348 (56%), Gaps = 19/348 (5%)
Frame = +2
Query: 56 LCISSPLGFTMSKSGAMDLASNLGGKIDKSDVLSAVERYEQYHVFHGGDEE-ERKANYTD 232
LC+ P A+DL+ GG I V + Y+QY F +E E D
Sbjct: 21 LCVLGPA--ERKGKRAVDLS---GGSISAEKV---QDNYKQYWSFFRRPKEIETAEKVPD 72
Query: 233 MVNEYYDLATSFYEYGWGESFHFAHRWNGESLRESIKRHEHFLALQLGVKPGQKVLDVGC 412
V+ +Y+L T YE+GWG+SFHF+ G+S +++ + HE + VKPGQK+LDVGC
Sbjct: 73 FVDTFYNLVTDIYEWGWGQSFHFSPSIPGKSHKDATRLHEEMAVDLIQVKPGQKILDVGC 132
Query: 413 GIGGPLREIARFSNSSVTGINNNEYQITRGKELNRLAGVDKTCGFVKADFMKMPFPENTF 592
G+GGP+R IA S ++V GI NEYQ+ R + N+ AG+D C V +F++MPF +N+F
Sbjct: 133 GVGGPMRAIASHSRANVVGITINEYQVNRARLHNKKAGLDALCEVVCGNFLQMPFDDNSF 192
Query: 593 DAVYAIEATCHAPDAYGCYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAQHQKIKAEIEIG 772
D Y+IEATCHAP Y EIYRVLKPG + +YEW T+ F ++ +H ++ IE G
Sbjct: 193 DGAYSIEATCHAPKLEEVYAEIYRVLKPGSMYVSYEWVTTEKFKAEDDEHVEVIQGIERG 252
Query: 773 DGLPDIRLTSKCLEALKQAGFEVIWEKDLAKDSPVPWYLPLDKNHFSLSSFRLTAVGRSI 952
D LP +R E K+ GFE++ EKDLA PW+ L + +
Sbjct: 253 DALPGLRAYVDIAETAKKVGFEIVKEKDLASPPAEPWWTRLKMGRLAYWRNHI------- 305
Query: 953 TKNMVKLLEYIRLAPKGSQRVSDFLEKAAEGLVDGGRREIFTPMYFFL 1096
+V++L + +APKG+ V + L K A+ L GG IF+PM+ L
Sbjct: 306 ---VVQILSAVGVAPKGTVDVHEMLFKTADYLTRGGETGIFSPMHMIL 350
>sp|Q96WX4|ERG6_PNECA Sterol 24-C-methyltransferase OS=Pneumocystis carinii
GN=erg6 PE=2 SV=1
Length = 377
Score = 250 bits (637), Expect = 2e-065
Identities = 116/243 (47%), Positives = 162/243 (66%), Gaps = 1/243 (0%)
Frame = +2
Query: 203 EEERKANYTDMVNEYYDLATSFYEYGWGESFHFAHRWNGESLRESIKRHEHFLALQLGVK 382
++ER Y + YY+L T FYEYGW SFHF ES ++I RHEH++AL G++
Sbjct: 66 QQERFKFYATLTRHYYNLVTDFYEYGWSTSFHFCRFAKDESFSQAIARHEHYIALHAGIR 125
Query: 383 PGQKVLDVGCGIGGPLREIARFSNSSVTGINNNEYQITRGKELNRLAGVDKTCGFVKADF 562
G+ VLDVGCG+GGP +I+ F+ +++ G+NNN+YQI R K + G+ F+K DF
Sbjct: 126 EGETVLDVGCGVGGPACQISVFTGANIVGLNNNDYQIQRAKYYSEKKGLSDKLKFIKGDF 185
Query: 563 MKMPFPENTFDAVYAIEATCHAPDAYGCYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAQH 742
M+MPFPEN+FD +Y+IEAT HAP G Y EIYRVLKPG +A+YEW M + +D ++ +H
Sbjct: 186 MQMPFPENSFDKIYSIEATIHAPSLEGVYSEIYRVLKPGGLYASYEWVMLNKYDENDPEH 245
Query: 743 QKIKAEIEIGDGLPDIRLTSKCLEALKQAGFEVIWEKDLA-KDSPVPWYLPLDKNHFSLS 919
Q+I IEIGD +P I + AL + GFE+I ++L+ K+SP+PWY LD + +
Sbjct: 246 QQIVYGIEIGDSIPKISKIGEAEAALIKVGFEIIHSEELSTKNSPLPWYYYLDGDLRKVR 305
Query: 920 SFR 928
SFR
Sbjct: 306 SFR 308
>sp|Q5EN22|ERG6_MAGGR Sterol 24-C-methyltransferase OS=Magnaporthe grisea
GN=ERG6 PE=2 SV=2
Length = 390
Score = 244 bits (622), Expect = 1e-063
Identities = 115/242 (47%), Positives = 162/242 (66%), Gaps = 3/242 (1%)
Frame = +2
Query: 206 EERKANYTDMVNEYYDLATSFYEYGWGESFHFAHRWNGESLRESIKRHEHFLALQLGVKP 385
EERKA+Y + +YY+L T FYEYGWG+SFHF GE+ +I R+EH LA ++G+K
Sbjct: 75 EERKADYATLTRQYYNLVTDFYEYGWGQSFHFCTFAPGETFASAITRYEHTLAHRIGIKK 134
Query: 386 GQKVLDVGCGIGGPLREIARFSNSSVTGINNNEYQITRGKELNRLA--GVDKTCGFVKAD 559
G KVLD+GCG+GGP R+IA+F+ +++TGI NEYQ+ R + + G + FV+ D
Sbjct: 135 GMKVLDIGCGVGGPARQIAKFTGANITGITINEYQVERARRYAEMEGYGAGEQLKFVQGD 194
Query: 560 FMKMPFPENTFDAVYAIEATCHAPDAYGCYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAQ 739
FM +PF + TFDAVY+IEAT HAP YK+I+ VLKPG F YEW MTDA+D ++
Sbjct: 195 FMALPFEKETFDAVYSIEATVHAPKLEDVYKQIFNVLKPGGIFGLYEWVMTDAYDENDPH 254
Query: 740 HQKIKAEIEIGDGLPDIRLTSKCLEALKQAGFEVIWEKDLAKDSP-VPWYLPLDKNHFSL 916
H++I+ IE G G+ +++ + A+K AGFE++ +DLA +S PWY PL N +
Sbjct: 255 HKEIRFGIEHGGGIANLQTAQTAIAAIKAAGFELLESEDLADNSDRAPWYWPLGGNAWQY 314
Query: 917 SS 922
+S
Sbjct: 315 AS 316
>sp|Q94JS4|SMT3B_ARATH 24-methylenesterol C-methyltransferase 3 OS=Arabidopsis
thaliana GN=SMT3 PE=2 SV=1
Length = 359
Score = 234 bits (595), Expect = 2e-060
Identities = 119/260 (45%), Positives = 158/260 (60%), Gaps = 5/260 (1%)
Frame = +2
Query: 113 ASNL-GGKIDKSDVLSAVERYEQYHVFHGGDEE-ERKANYTDMVNEYYDLATSFYEYGWG 286
AS+L GG I V + Y QY F +E E D V+ +Y+L T YE+GWG
Sbjct: 34 ASDLSGGSISAEKV---KDNYNQYWSFFRKPKEIESAEKVPDFVDTFYNLVTDIYEWGWG 90
Query: 287 ESFHFAHRWNGESLRESIKRHEHFLALQLGVKPGQKVLDVGCGIGGPLREIARFSNSSVT 466
+SFHF+ G+S +++ + HE + VKPGQK+LD GCG+GGP+R IA S + VT
Sbjct: 91 QSFHFSPHVPGKSDKDATRIHEEMAVDLIKVKPGQKILDAGCGVGGPMRAIAAHSKAQVT 150
Query: 467 GINNNEYQITRGKELNRLAGVDKTCGFVKADFMKMPFPENTFDAVYAIEATCHAPDAYGC 646
GI NEYQ+ R K N+ AG+D C V +F+KMPF ENTFD Y+IEATCHAP
Sbjct: 151 GITINEYQVQRAKLHNKKAGLDSLCNVVCGNFLKMPFDENTFDGAYSIEATCHAPKLEEV 210
Query: 647 YKEIYRVLKPGQCFAAYEWCMTDAFDPDNAQHQKIKAEIEIGDGLPDIRLTSKCLEALKQ 826
Y EI+RV+KPG F +YEW T+ + D+ +H+ + IE GD LP +R + K+
Sbjct: 211 YSEIFRVMKPGSLFVSYEWVTTEKYRDDDEEHKDVIQGIERGDALPGLRSYADIAVTAKK 270
Query: 827 AGFEVIWEKDLAKDSPVPWY 886
GFEV+ EKDLAK PW+
Sbjct: 271 VGFEVVKEKDLAKPPSKPWW 290
>sp|O82427|SMT2_ORYSJ 24-methylenesterol C-methyltransferase 2 OS=Oryza sativa
subsp. japonica GN=Smt2-1 PE=2 SV=2
Length = 363
Score = 214 bits (543), Expect = 2e-054
Identities = 107/249 (42%), Positives = 146/249 (58%), Gaps = 5/249 (2%)
Frame = +2
Query: 164 ERYEQYHVFHGGDEEERKANYT-----DMVNEYYDLATSFYEYGWGESFHFAHRWNGESL 328
++Y QY F +E + V+ +Y+L T YE+GWG+SFHF+ G S
Sbjct: 50 DKYTQYWSFFRRPKETATTEASAEKVPAFVDTFYNLVTDIYEWGWGQSFHFSPSLPGRSH 109
Query: 329 RESIKRHEHFLALQLGVKPGQKVLDVGCGIGGPLREIARFSNSSVTGINNNEYQITRGKE 508
RE+ + HE +A L KPG ++LDVGCG+GGP+R IA S S+V GI NEYQ+ R +
Sbjct: 110 REATRVHEERVADLLQAKPGHRLLDVGCGVGGPMRAIAAHSGSNVVGITINEYQVNRARA 169
Query: 509 LNRLAGVDKTCGFVKADFMKMPFPENTFDAVYAIEATCHAPDAYGCYKEIYRVLKPGQCF 688
NR AG+D C V +F+ MPF + +FD Y+IEATCHAP Y E++RVLKPG +
Sbjct: 170 HNRKAGLDSRCEVVCGNFLSMPFSDASFDGAYSIEATCHAPRLQDVYGEVFRVLKPGGLY 229
Query: 689 AAYEWCMTDAFDPDNAQHQKIKAEIEIGDGLPDIRLTSKCLEALKQAGFEVIWEKDLAKD 868
+YEW T + DN +H + IE GD LP +R + K+ GFEV+ E DLA
Sbjct: 230 VSYEWVTTSLYRADNPEHVEAIHGIERGDALPGLRRQDEIASIAKEVGFEVLKELDLALP 289
Query: 869 SPVPWYLPL 895
+PW+ L
Sbjct: 290 PALPWWTRL 298
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,893,998,746
Number of Sequences: 518415
Number of Extensions: 41893998746
Number of Successful Extensions: 306640000
Number of sequences better than 0.0: 0
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