BLASTX 7.6.2
Query= UN10490 /QuerySize=1710
(1709 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54JE4|ODO1_DICDI 2-oxoglutarate dehydrogenase, mitochondrial... 483 2e-135
sp|Q60HE2|ODO1_MACFA 2-oxoglutarate dehydrogenase, mitochondrial... 436 4e-121
sp|Q02218|ODO1_HUMAN 2-oxoglutarate dehydrogenase, mitochondrial... 435 5e-121
sp|Q5RCB8|ODO1_PONAB 2-oxoglutarate dehydrogenase, mitochondrial... 433 2e-120
sp|Q60597|ODO1_MOUSE 2-oxoglutarate dehydrogenase, mitochondrial... 430 2e-119
sp|Q5XI78|ODO1_RAT 2-oxoglutarate dehydrogenase, mitochondrial O... 430 2e-119
sp|Q148N0|ODO1_BOVIN 2-oxoglutarate dehydrogenase, mitochondrial... 429 5e-119
sp|O61199|ODO1_CAEEL 2-oxoglutarate dehydrogenase, mitochondrial... 416 2e-115
sp|Q623T0|ODO1_CAEBR 2-oxoglutarate dehydrogenase, mitochondrial... 416 3e-115
sp|P20967|ODO1_YEAST 2-oxoglutarate dehydrogenase, mitochondrial... 385 8e-106
sp|O74378|ODO1_SCHPO 2-oxoglutarate dehydrogenase, mitochondrial... 379 6e-104
sp|Q9ULD0|OGDHL_HUMAN 2-oxoglutarate dehydrogenase-like, mitocho... 327 3e-088
sp|Q68EW0|OGDHL_XENLA 2-oxoglutarate dehydrogenase-like, mitocho... 324 1e-087
sp|Q5R9L8|OGDHL_PONAB 2-oxoglutarate dehydrogenase-like, mitocho... 324 2e-087
sp|Q6P6Z8|ODO1_XENLA 2-oxoglutarate dehydrogenase, mitochondrial... 321 1e-086
sp|Q4UKI8|ODO1_RICFE 2-oxoglutarate dehydrogenase E1 component O... 257 3e-067
sp|Q72PJ7|ODO1_LEPIC 2-oxoglutarate dehydrogenase E1 component O... 256 4e-067
sp|Q8F6S7|ODO1_LEPIN 2-oxoglutarate dehydrogenase E1 component O... 256 4e-067
sp|Q65IH4|ODO1_BACLD 2-oxoglutarate dehydrogenase E1 component O... 253 4e-066
sp|Q1RHI4|ODO1_RICBR 2-oxoglutarate dehydrogenase E1 component O... 250 2e-065
>sp|Q54JE4|ODO1_DICDI 2-oxoglutarate dehydrogenase, mitochondrial
OS=Dictyostelium discoideum GN=ogdh PE=3 SV=1
Length = 1013
Score = 483 bits (1242), Expect = 2e-135
Identities = 233/478 (48%), Positives = 315/478 (65%), Gaps = 15/478 (3%)
Frame = +2
Query: 17 LQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASKEYIPQKRDWLASHWTGFKSPEQ 196
++ Y KL+ +T+E +++ + + ++ +++P DWL S W GFKSP +
Sbjct: 529 IEKYSNKLIAEKVITQEQYLQMKNIIHESYEKGYQDGMKHVPNAEDWLESRWEGFKSPIE 588
Query: 197 ISRIRNTGVKPEILKNVGKAISTFPENFKPHRGVKRVYEQRAQMIESGEGIDWGLGEALA 376
+ TG+ ++L+ +GK + T P F+ H +KR+ +++ M + G G DW EALA
Sbjct: 589 LGNPGRTGIDQDLLQKIGKVLYTEPSGFEVHSTIKRLLKEKKDMFDKGTGFDWATAEALA 648
Query: 377 FATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYCPLDHLTM---NQDPEMFTVS 547
F +L+++GNHVRLSGQDVERGTFSHRH+V HDQ+T + Y PL L +D F S
Sbjct: 649 FGSLLLDGNHVRLSGQDVERGTFSHRHAVWHDQKTDQTYAPLTKLATALGKKDAAEFVAS 708
Query: 548 NSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQTGLV 727
NSSLSEF VLGFELGYS+ENP++L++WEAQFGDF+NGAQV+ DQFISSGE KW+RQ+GL
Sbjct: 709 NSSLSEFAVLGFELGYSLENPDALILWEAQFGDFSNGAQVIIDQFISSGEQKWMRQSGLT 768
Query: 728 VLLPHGYDGQGPEHSSGRLERFLQMSDDNPFVIPEMDSTLRKQIQECNWQIVNVTTPANY 907
+LLPHGYDG GPEHSS R+ER+LQ+ D +P IP + RKQ Q CN Q++N +TP NY
Sbjct: 769 MLLPHGYDGAGPEHSSCRIERYLQLCDSDPNKIPPKEEAERKQSQHCNMQVLNCSTPVNY 828
Query: 908 FHVLRRQIHRDFRKPLIVMAPKNLLRHKKCVSNLSEFDDVKGHPGFDKQGTRFKRLIKDQ 1087
FH LRRQ+HRDFRKPL++ PK LLR++K S EF + D + DQ
Sbjct: 829 FHALRRQVHRDFRKPLVIATPKYLLRYEKSFSTAKEFSN-------DSFTRLYPEAFPDQ 881
Query: 1088 SGHSDLEEGIRRLVLCSGKVYYELDEERQKSGTNDIAICRVEQLCPFPYDLIQRELKRYP 1267
+ E I R+V C+G+VYY L R+ + D+AI RVEQL PFP+DL+ +L+ YP
Sbjct: 882 ---INKPEKINRIVFCTGQVYYNLIASRESNNIKDVAIIRVEQLHPFPFDLVAEQLQHYP 938
Query: 1268 NAEIVWCQEEPMNMGGYQYIAPRLCTAMKALNRGSFSDIKYVGRLPSAATATGFYQLH 1441
NA+ +WCQEEPMNMG + YI P + K +NR +DI Y GR SA+ A + LH
Sbjct: 939 NAKAIWCQEEPMNMGYWNYIYPYFISTFKHINRP--ADITYTGRPSSASPAVASHTLH 994
>sp|Q60HE2|ODO1_MACFA 2-oxoglutarate dehydrogenase, mitochondrial OS=Macaca
fascicularis GN=OGDH PE=2 SV=1
Length = 1023
Score = 436 bits (1119), Expect = 4e-121
Identities = 232/488 (47%), Positives = 313/488 (64%), Gaps = 29/488 (5%)
Frame = +2
Query: 17 LQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASK-EYIPQKRDWLASHWTGF---- 181
LQ Y E L+ G V + + ++ K I E F SK E I + WL S W GF
Sbjct: 537 LQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFTLD 596
Query: 182 KSPEQISRIRNTGVKPEILKNVGKAISTFP-ENFKPHRGVKRVYEQRAQMIESGEGIDWG 358
P +S +TG+ +IL ++G S+ P ENF H G+ R+ + R +M+++ +DW
Sbjct: 597 GQPRSMS-CPSTGLTEDILTHIGNVASSVPVENFTIHGGLSRILKTRGEMVKN-RTVDWA 654
Query: 359 LGEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYC-PLDHLTMNQDPEM 535
L E +AF +L+ EG H+RLSGQDVERGTFSHRH VLHDQ + C P++HL NQ P
Sbjct: 655 LAEYMAFGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAP-- 712
Query: 536 FTVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQ 715
+TV NSSLSE+GVLGFELG++M +PN+LV+WEAQFGDF N AQ + DQFI G+AKW+RQ
Sbjct: 713 YTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQ 772
Query: 716 TGLVVLLPHGYDGQGPEHSSGRLERFLQMSDDNPFVIPEMDSTL--RKQIQECNWQIVNV 889
G+V+LLPHG +G GPEHSS R ERFLQM +D+P V+P++ Q+ +CNW +VN
Sbjct: 773 NGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQLHDCNWVVVNC 832
Query: 890 TTPANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKKCVSNLSEFDDVKGHPGFDKQGTRFK 1069
+TP N+FHVLRRQI FRKPLI+ PK+LLRH + S+ E GT F+
Sbjct: 833 STPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEM----------LPGTHFQ 882
Query: 1070 RLIKDQSGHSDLEEGIRRLVLCSGKVYYELDEERQ-KSGTNDIAICRVEQLCPFPYDLIQ 1246
R+I + + E ++RL+ C+GKVYY+L ER+ + +AI R+EQL PFP+DL+
Sbjct: 883 RVIPEDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLL 942
Query: 1247 RELKRYPNAEIVWCQEEPMNMGGYQYIAPRLCTAMKALNRGSFSDIKYVGRLPSAATATG 1426
+E+++YPNAE+ WCQEE N G Y Y+ PRL T + + Y GR P+AA ATG
Sbjct: 943 KEVQKYPNAELAWCQEEHKNQGYYDYVKPRLRTTISRA-----KPVWYAGRDPAAAPATG 997
Query: 1427 FYQLHVKE 1450
+ H+ E
Sbjct: 998 NKKTHLTE 1005
>sp|Q02218|ODO1_HUMAN 2-oxoglutarate dehydrogenase, mitochondrial OS=Homo
sapiens GN=OGDH PE=1 SV=3
Length = 1023
Score = 435 bits (1118), Expect = 5e-121
Identities = 232/488 (47%), Positives = 313/488 (64%), Gaps = 29/488 (5%)
Frame = +2
Query: 17 LQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASK-EYIPQKRDWLASHWTGF---- 181
LQ Y E L+ G V + + ++ K I E F SK E I + WL S W GF
Sbjct: 537 LQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFTLD 596
Query: 182 KSPEQISRIRNTGVKPEILKNVGKAISTFP-ENFKPHRGVKRVYEQRAQMIESGEGIDWG 358
P +S +TG+ +IL ++G S+ P ENF H G+ R+ + R +M+++ +DW
Sbjct: 597 GQPRSMS-CPSTGLTEDILTHIGNVASSVPVENFTIHGGLSRILKTRGEMVKN-RTVDWA 654
Query: 359 LGEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYC-PLDHLTMNQDPEM 535
L E +AF +L+ EG H+RLSGQDVERGTFSHRH VLHDQ + C P++HL NQ P
Sbjct: 655 LAEYMAFGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAP-- 712
Query: 536 FTVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQ 715
+TV NSSLSE+GVLGFELG++M +PN+LV+WEAQFGDF N AQ + DQFI G+AKW+RQ
Sbjct: 713 YTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQ 772
Query: 716 TGLVVLLPHGYDGQGPEHSSGRLERFLQMSDDNPFVIPEMDSTL--RKQIQECNWQIVNV 889
G+V+LLPHG +G GPEHSS R ERFLQM +D+P V+P++ Q+ +CNW +VN
Sbjct: 773 NGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNC 832
Query: 890 TTPANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKKCVSNLSEFDDVKGHPGFDKQGTRFK 1069
+TP N+FHVLRRQI FRKPLI+ PK+LLRH + S+ E GT F+
Sbjct: 833 STPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEM----------LPGTHFQ 882
Query: 1070 RLIKDQSGHSDLEEGIRRLVLCSGKVYYELDEERQ-KSGTNDIAICRVEQLCPFPYDLIQ 1246
R+I + + E ++RL+ C+GKVYY+L ER+ + +AI R+EQL PFP+DL+
Sbjct: 883 RVIPEDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLL 942
Query: 1247 RELKRYPNAEIVWCQEEPMNMGGYQYIAPRLCTAMKALNRGSFSDIKYVGRLPSAATATG 1426
+E+++YPNAE+ WCQEE N G Y Y+ PRL T + + Y GR P+AA ATG
Sbjct: 943 KEVQKYPNAELAWCQEEHKNQGYYDYVKPRLRTTISRA-----KPVWYAGRDPAAAPATG 997
Query: 1427 FYQLHVKE 1450
+ H+ E
Sbjct: 998 NKKTHLTE 1005
>sp|Q5RCB8|ODO1_PONAB 2-oxoglutarate dehydrogenase, mitochondrial OS=Pongo
abelii GN=OGDH PE=2 SV=1
Length = 1023
Score = 433 bits (1113), Expect = 2e-120
Identities = 231/488 (47%), Positives = 313/488 (64%), Gaps = 29/488 (5%)
Frame = +2
Query: 17 LQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASK-EYIPQKRDWLASHWTGF---- 181
LQ Y E L+ G V + + ++ K I E F SK E I + WL S W GF
Sbjct: 537 LQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFTLD 596
Query: 182 KSPEQISRIRNTGVKPEILKNVGKAISTFP-ENFKPHRGVKRVYEQRAQMIESGEGIDWG 358
P +S +TG+ +IL ++G S+ P ENF H G+ R+ + R +M+++ +DW
Sbjct: 597 GQPRSMS-CPSTGLTEDILTHIGNVASSVPVENFTIHGGLSRILKTRGEMVKN-RTVDWA 654
Query: 359 LGEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYC-PLDHLTMNQDPEM 535
L E +AF +L+ EG H+RLSGQDVERGTFSHRH VLHDQ + C P++HL NQ P
Sbjct: 655 LAEYMAFGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAP-- 712
Query: 536 FTVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQ 715
+TV NSSLSE+GVLGFELG++M +PN+LV+WEAQFGDF N AQ + DQFI G+AKW+RQ
Sbjct: 713 YTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQ 772
Query: 716 TGLVVLLPHGYDGQGPEHSSGRLERFLQMSDDNPFVIPEMDSTL--RKQIQECNWQIVNV 889
G+V+LLPHG +G GPEHSS R ERFLQM +D+P V+P++ Q+ +CNW +VN
Sbjct: 773 NGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNC 832
Query: 890 TTPANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKKCVSNLSEFDDVKGHPGFDKQGTRFK 1069
+TP N+FHVLRRQI FRKPLI+ PK+LLRH + S+ E GT F+
Sbjct: 833 STPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEM----------LPGTHFQ 882
Query: 1070 RLIKDQSGHSDLEEGIRRLVLCSGKVYYELDEERQ-KSGTNDIAICRVEQLCPFPYDLIQ 1246
R+I + + E ++RL+ C+GKVYY+L ER+ + +AI R+EQL PFP+DL+
Sbjct: 883 RVIPEDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLL 942
Query: 1247 RELKRYPNAEIVWCQEEPMNMGGYQYIAPRLCTAMKALNRGSFSDIKYVGRLPSAATATG 1426
+E+++YP+AE+ WCQEE N G Y Y+ PRL T + + Y GR P+AA ATG
Sbjct: 943 KEVQKYPSAELAWCQEEHKNQGYYDYVKPRLRTTISRA-----KPVWYAGRDPAAAPATG 997
Query: 1427 FYQLHVKE 1450
+ H+ E
Sbjct: 998 NKKTHLTE 1005
>sp|Q60597|ODO1_MOUSE 2-oxoglutarate dehydrogenase, mitochondrial OS=Mus
musculus GN=Ogdh PE=1 SV=3
Length = 1023
Score = 430 bits (1105), Expect = 2e-119
Identities = 230/487 (47%), Positives = 316/487 (64%), Gaps = 27/487 (5%)
Frame = +2
Query: 17 LQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASK-EYIPQKRDWLASHWTGFKSPE 193
LQ Y E L+ G V + + ++ K I E F SK E I + WL S W GF + +
Sbjct: 537 LQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFTRSKDEKILHIKHWLDSPWPGFFTLD 596
Query: 194 QISR---IRNTGVKPEILKNVGKAISTFP-ENFKPHRGVKRVYEQRAQMIESGEGIDWGL 361
R +TG++ ++L ++GK S+ P ENF H G+ R+ + R +++ + +DW L
Sbjct: 597 GQPRSMTCPSTGLEEDVLFHIGKVASSVPVENFTIHGGLSRILKTRRELV-TNRTVDWAL 655
Query: 362 GEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYC-PLDHLTMNQDPEMF 538
E +AF +L+ EG HVRLSGQDVERGTFSHRH VLHDQ + C P++HL NQ P +
Sbjct: 656 AEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAP--Y 713
Query: 539 TVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQT 718
TV NSSLSE+GVLGFELG++M +PN+LV+WEAQFGDF N AQ + DQFI G+AKW+RQ
Sbjct: 714 TVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFNNMAQCIIDQFICPGQAKWVRQN 773
Query: 719 GLVVLLPHGYDGQGPEHSSGRLERFLQMSDDNPFVIPEM--DSTLRKQIQECNWQIVNVT 892
G+V+LLPHG +G GPEHSS R ERFLQM +D+P V+P++ ++ Q+ +CNW +VN +
Sbjct: 774 GIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLQEENFDINQLYDCNWIVVNCS 833
Query: 893 TPANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKKCVSNLSEFDDVKGHPGFDKQGTRFKR 1072
TP N+FHVLRRQI FRKPLIV PK+LLRH + ++ E GT F+R
Sbjct: 834 TPGNFFHVLRRQILLPFRKPLIVFTPKSLLRHPEARTSFDEM----------LPGTHFQR 883
Query: 1073 LIKDQSGHSDLEEGIRRLVLCSGKVYYELDEERQ-KSGTNDIAICRVEQLCPFPYDLIQR 1249
+I + + ++RL+ C+GKVYY+L ER+ ++ ++AI R+EQL PFP+DL+ +
Sbjct: 884 VIPENGPAAQDPHKVKRLLFCTGKVYYDLTRERKARNMEEEVAITRIEQLSPFPFDLLLK 943
Query: 1250 ELKRYPNAEIVWCQEEPMNMGGYQYIAPRLCTAMKALNRGSFSDIKYVGRLPSAATATGF 1429
E ++YPNAE+ WCQEE N G Y Y+ PRL T + + Y GR P+AA ATG
Sbjct: 944 EAQKYPNAELAWCQEEHKNQGYYDYVKPRLRTTIDRA-----KPVWYAGRDPAAAPATGN 998
Query: 1430 YQLHVKE 1450
+ H+ E
Sbjct: 999 KKTHLTE 1005
>sp|Q5XI78|ODO1_RAT 2-oxoglutarate dehydrogenase, mitochondrial OS=Rattus
norvegicus GN=Ogdh PE=1 SV=1
Length = 1023
Score = 430 bits (1104), Expect = 2e-119
Identities = 230/487 (47%), Positives = 314/487 (64%), Gaps = 27/487 (5%)
Frame = +2
Query: 17 LQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASK-EYIPQKRDWLASHWTGFKSPE 193
LQ Y E L+ G V + + ++ K I E F SK E I + WL S W GF + +
Sbjct: 537 LQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFTRSKDEKILHIKHWLDSPWPGFFTLD 596
Query: 194 QISR---IRNTGVKPEILKNVGKAISTFP-ENFKPHRGVKRVYEQRAQMIESGEGIDWGL 361
R +TG++ +IL ++G S+ P ENF H G+ R+ + R +++ + +DW L
Sbjct: 597 GQPRSMTCPSTGLEEDILTHIGNVASSVPVENFTIHGGLSRILKTRRELV-TNRTVDWAL 655
Query: 362 GEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYC-PLDHLTMNQDPEMF 538
E +AF +L+ EG HVRLSGQDVERGTFSHRH VLHDQ + C P++HL NQ P +
Sbjct: 656 AEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAP--Y 713
Query: 539 TVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQT 718
TV NSSLSE+GVLGFELG++M +PN+LV+WEAQFGDF N AQ + DQFI G+AKW+RQ
Sbjct: 714 TVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFNNMAQCIIDQFICPGQAKWVRQN 773
Query: 719 GLVVLLPHGYDGQGPEHSSGRLERFLQMSDDNPFVIPEM--DSTLRKQIQECNWQIVNVT 892
G+V+LLPHG +G GPEHSS R ERFLQM +D+P V+P + ++ Q+ +CNW +VN +
Sbjct: 774 GIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPNLQEENFDISQLYDCNWIVVNCS 833
Query: 893 TPANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKKCVSNLSEFDDVKGHPGFDKQGTRFKR 1072
TP N+FHVLRRQI FRKPLIV PK+LLRH + ++ E GT F+R
Sbjct: 834 TPGNFFHVLRRQILLPFRKPLIVFTPKSLLRHPEARTSFDEM----------LPGTHFQR 883
Query: 1073 LIKDQSGHSDLEEGIRRLVLCSGKVYYELDEERQ-KSGTNDIAICRVEQLCPFPYDLIQR 1249
+I + + + ++RL+ C+GKVYY+L ER+ + ++AI R+EQL PFP+DL+ +
Sbjct: 884 VIPEDGPAAQNPDKVKRLLFCTGKVYYDLTRERKARDMAEEVAITRIEQLSPFPFDLLLK 943
Query: 1250 ELKRYPNAEIVWCQEEPMNMGGYQYIAPRLCTAMKALNRGSFSDIKYVGRLPSAATATGF 1429
E ++YPNAE+ WCQEE N G Y Y+ PRL T + + Y GR P+AA ATG
Sbjct: 944 EAQKYPNAELAWCQEEHKNQGYYDYVKPRLRTTIDRA-----KPVWYAGRDPAAAPATGN 998
Query: 1430 YQLHVKE 1450
+ H+ E
Sbjct: 999 KKTHLTE 1005
>sp|Q148N0|ODO1_BOVIN 2-oxoglutarate dehydrogenase, mitochondrial OS=Bos taurus
GN=OGDH PE=2 SV=1
Length = 1023
Score = 429 bits (1101), Expect = 5e-119
Identities = 228/487 (46%), Positives = 312/487 (64%), Gaps = 27/487 (5%)
Frame = +2
Query: 17 LQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASK-EYIPQKRDWLASHWTGFKSPE 193
LQ Y E L+ G V + + ++ K I E F SK E I + WL S W GF + +
Sbjct: 537 LQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFTLD 596
Query: 194 QISR---IRNTGVKPEILKNVGKAISTFP-ENFKPHRGVKRVYEQRAQMIESGEGIDWGL 361
R +TG+ +IL ++G S+ P E+F H G+ R+ + R +++++ +DW L
Sbjct: 597 GQPRSMTCPSTGLTEDILTHIGNVASSVPVEDFTIHGGLSRILKTRGELVKN-RTVDWAL 655
Query: 362 GEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYC-PLDHLTMNQDPEMF 538
E +AF +L+ EG H+RLSGQDVERGTFSHRH VLHDQ + C P++HL NQ P +
Sbjct: 656 AEYMAFGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAP--Y 713
Query: 539 TVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQT 718
TV NSSLSE+GVLGFELG++M +PN+LV+WEAQFGDF N AQ + DQFI G+AKW+RQ
Sbjct: 714 TVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQN 773
Query: 719 GLVVLLPHGYDGQGPEHSSGRLERFLQMSDDNPFVIPEMDSTL--RKQIQECNWQIVNVT 892
G+V+LLPHG +G GPEHSS R ERFLQM +D+P V+P++ Q+ +CNW +VN +
Sbjct: 774 GIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNCS 833
Query: 893 TPANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKKCVSNLSEFDDVKGHPGFDKQGTRFKR 1072
TP N+FHVLRRQI FRKPLI+ PK+LLRH + SN E GT F+R
Sbjct: 834 TPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSNFDEM----------LPGTHFQR 883
Query: 1073 LIKDQSGHSDLEEGIRRLVLCSGKVYYELDEERQ-KSGTNDIAICRVEQLCPFPYDLIQR 1249
+I + + ++RL+ C+GKVYY+L ER+ + +AI R+EQL PFP+DL+ +
Sbjct: 884 VIPEDGPAAQNPGNVKRLLFCTGKVYYDLTRERKARDMVEQVAITRIEQLSPFPFDLLLQ 943
Query: 1250 ELKRYPNAEIVWCQEEPMNMGGYQYIAPRLCTAMKALNRGSFSDIKYVGRLPSAATATGF 1429
E+++YP+AE+ WCQEE N G Y Y+ PRL T + + Y GR P+AA ATG
Sbjct: 944 EVQKYPSAELAWCQEEHKNQGYYDYVKPRLRTTISRA-----KPVWYAGRDPAAAPATGN 998
Query: 1430 YQLHVKE 1450
+ H+ E
Sbjct: 999 KKTHLTE 1005
>sp|O61199|ODO1_CAEEL 2-oxoglutarate dehydrogenase, mitochondrial
OS=Caenorhabditis elegans GN=T22B11.5 PE=1 SV=2
Length = 1029
Score = 416 bits (1069), Expect = 2e-115
Identities = 215/450 (47%), Positives = 300/450 (66%), Gaps = 20/450 (4%)
Frame = +2
Query: 11 SSLQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFE-ASKEYIPQKRDWLASHWTGFKS 187
++L+ YQEK+L G ++ + + K SIL + +E A K + RDWL S W F
Sbjct: 539 TALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFK 598
Query: 188 PEQISRIRNTGVKPEILKNVGKAISTFPENFKPHRGVKRVYEQRAQMIESGEGIDWGLGE 367
++ +TG++ E ++ + S +PE F HRG++R + R QM++ +DW GE
Sbjct: 599 KRDPLKLPSTGIEQENIEQIIGKFSQYPEGFNLHRGLERTLKGRQQMLKD-NSLDWACGE 657
Query: 368 ALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEE-YCPLDHLTMNQDPEMFTV 544
ALAF +L+ EG HVRLSGQDV+RGTFSHRH VLHDQ+ ++ Y PL+ L+ Q +TV
Sbjct: 658 ALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGE--YTV 715
Query: 545 SNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQTGL 724
NSSLSE+ VLGFELGYSM +PNSLVIWEAQFGDF+N AQ + DQFISSG++KW+RQ+GL
Sbjct: 716 CNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGL 775
Query: 725 VVLLPHGYDGQGPEHSSGRLERFLQMSDDNPFVIPE---MDSTLR-KQIQECNWQIVNVT 892
V+LLPHGY+G GPEHSS R ERFLQM +++ + E + T +Q+ + NW + N T
Sbjct: 776 VMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCT 835
Query: 893 TPANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKKCVSNLSEFDDVKGHPGFDKQGTRFKR 1072
TPAN +H+LRRQ+ FRKP +V +PK+LLRH S + +F + G+ F+R
Sbjct: 836 TPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDF----------QSGSNFQR 885
Query: 1073 LIKDQSGHSDLEEGIRRLVLCSGKVYYELDEERQKSG-TNDIAICRVEQLCPFPYDLIQR 1249
+I + S ++R+V C+GKVYY++ R+ G ND+A+ RVEQL PFPYDL+Q+
Sbjct: 886 VIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQ 945
Query: 1250 ELKRYPNAEIVWCQEEPMNMGGYQYIAPRL 1339
E ++Y AEI+W QEE NMG + ++ PR+
Sbjct: 946 ECRKYQGAEILWAQEEHKNMGAWSFVQPRI 975
>sp|Q623T0|ODO1_CAEBR 2-oxoglutarate dehydrogenase, mitochondrial
OS=Caenorhabditis briggsae GN=CBG01737 PE=3 SV=1
Length = 1027
Score = 416 bits (1068), Expect = 3e-115
Identities = 214/453 (47%), Positives = 302/453 (66%), Gaps = 26/453 (5%)
Frame = +2
Query: 11 SSLQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFE-ASKEYIPQKRDWLASHWTGFKS 187
++L+ YQEK+L G ++ + + K +IL + +E A K + RDWL S W F
Sbjct: 537 TALEKYQEKILNEGVANEQYVKEELTKYGAILEDAYENAQKVTYVRNRDWLDSPWDDFFK 596
Query: 188 PEQISRIRNTGVKPEILKNVGKAISTFPENFKPHRGVKRVYEQRAQMIESGEGIDWGLGE 367
++ +TG++ E ++++ ++PE F HRG++R + R QM++ +DW GE
Sbjct: 597 KRDPLKLPSTGIEQENIEHIIGKFGSYPEGFNLHRGLERTLKGRQQMLKD-NSLDWACGE 655
Query: 368 ALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEE-YCPLDHLTMNQDPE-MFT 541
ALAF +L+ EG HVRLSGQDVERGTFSHRH VLHDQ+ ++ Y PL+ L DP+ +T
Sbjct: 656 ALAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQKVDQKIYNPLNDLA---DPQGEYT 712
Query: 542 VSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQTG 721
V NSSLSE+ VLGFELGYSM +PNSLVIWEAQFGDF+N AQ + DQF+SSG++KW+RQ+G
Sbjct: 713 VCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFVSSGQSKWIRQSG 772
Query: 722 LVVLLPHGYDGQGPEHSSGRLERFLQMSDDNPFVIPEMDSTL------RKQIQECNWQIV 883
LV+LLPHGY+G GPEHSS R ERFLQM +++ + ++D +Q+ + NW +
Sbjct: 773 LVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEI--DLDKIAFGGTFEAQQLHDTNWIVA 830
Query: 884 NVTTPANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKKCVSNLSEFDDVKGHPGFDKQGTR 1063
N TTPAN +H+LRRQ+ FRKP +V +PK+LLRH S + +F + G+
Sbjct: 831 NCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDF----------QSGSN 880
Query: 1064 FKRLIKDQSGHSDLEEGIRRLVLCSGKVYYELDEERQKSG-TNDIAICRVEQLCPFPYDL 1240
F+R+I + S ++RLV C+GKVYY++ R+ G ND+A+ RVEQL PFPYDL
Sbjct: 881 FQRIIPETGAPSQNPPNVQRLVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDL 940
Query: 1241 IQRELKRYPNAEIVWCQEEPMNMGGYQYIAPRL 1339
+Q+E ++Y AEI+W QEE NMG + ++ PR+
Sbjct: 941 VQQECRKYQGAEIIWAQEEHKNMGAWSFVQPRI 973
>sp|P20967|ODO1_YEAST 2-oxoglutarate dehydrogenase, mitochondrial
OS=Saccharomyces cerevisiae GN=KGD1 PE=1 SV=2
Length = 1014
Score = 385 bits (987), Expect = 8e-106
Identities = 184/342 (53%), Positives = 254/342 (74%), Gaps = 7/342 (2%)
Frame = +2
Query: 11 SSLQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASKEYIPQKRDWLASHWTGFKSP 190
S + +Y EKL+ G +K+DID+ +K V ++ + FE +K+Y+P +R+WL + W GFKSP
Sbjct: 530 SVIDVYTEKLISEGTFSKKDIDEHKKWVWNLFEDAFEKAKDYVPSQREWLTAAWEGFKSP 589
Query: 191 EQISR----IRNTGVKPEILKNVGKAISTFPENFKPHRGVKRVYEQRAQMIESGEGIDWG 358
++++ T V LK +GK +S++PE F+ H+ +KR+ + R + IE+GEGIDW
Sbjct: 590 KELATEILPHEPTNVPESTLKELGKVLSSWPEGFEVHKNLKRILKNRGKSIETGEGIDWA 649
Query: 359 LGEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYCPLDHLTMNQDPEMF 538
GEALAF TLV++G +VR+SG+DVERGTFS RH+VLHDQ++ Y PL T+N + F
Sbjct: 650 TGEALAFGTLVLDGQNVRVSGEDVERGTFSQRHAVLHDQQSEAIYTPLS--TLNNEKADF 707
Query: 539 TVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQT 718
T++NSSLSE+GV+GFE GYS+ +P+ LV+WEAQFGDFAN AQV+ DQFI+ GE KW +++
Sbjct: 708 TIANSSLSEYGVMGFEYGYSLTSPDYLVMWEAQFGDFANTAQVIIDQFIAGGEQKWKQRS 767
Query: 719 GLVVLLPHGYDGQGPEHSSGRLERFLQMSDDNPFVIPEMDSTLRKQIQECNWQIVNVTTP 898
GLV+ LPHGYDGQGPEHSSGRLERFLQ+++++P P + L++Q Q+CN+Q+V TTP
Sbjct: 768 GLVLSLPHGYDGQGPEHSSGRLERFLQLANEDPRYFPS-EEKLQRQHQDCNFQVVYPTTP 826
Query: 899 ANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKKCVSNLSEFDD 1024
AN FH+LRRQ HR FRKPL + K LLRH S+LSEF +
Sbjct: 827 ANLFHILRRQQHRQFRKPLALFFSKQLLRHPLARSSLSEFTE 868
>sp|O74378|ODO1_SCHPO 2-oxoglutarate dehydrogenase, mitochondrial
OS=Schizosaccharomyces pombe GN=kgd1 PE=2 SV=1
Length = 1009
Score = 379 bits (971), Expect = 6e-104
Identities = 185/346 (53%), Positives = 244/346 (70%), Gaps = 7/346 (2%)
Frame = +2
Query: 8 PSSLQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASKEYIPQKRDWLASHWTGFKS 187
P + +IY ++LL+ V+K ++D +K+V IL FE+SK Y R+WL++ W GF S
Sbjct: 527 PPTFKIYTQQLLQEKTVSKAEVDAQEKRVWDILESSFESSKNYKSDHREWLSNPWVGFAS 586
Query: 188 PE----QISRIRNTGVKPEILKNVGKAISTFPENFKPHRGVKRVYEQRAQMIESGEGIDW 355
P+ +I TGV + LK +GKA+ T PE F HR +KR+ R + I SGEGID
Sbjct: 587 PKDLMTKILPSYPTGVNIDTLKQIGKALYTLPEGFDAHRNLKRILNNRNKSISSGEGIDM 646
Query: 356 GLGEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYCPLDHLTMNQDPEM 535
EALAF TL+ EG+HVR+SGQDVERGTFS RH+VLHDQ + Y PL+HL+ NQ
Sbjct: 647 PTAEALAFGTLLEEGHHVRVSGQDVERGTFSQRHAVLHDQSSENVYIPLNHLSPNQ--AS 704
Query: 536 FTVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQ 715
F + NSSLSE+GVLGFE GYS+ +PN+LV+WEAQFGDFAN AQ + DQFI++GE KWL++
Sbjct: 705 FVIRNSSLSEYGVLGFEYGYSLSSPNALVVWEAQFGDFANNAQCIIDQFIAAGETKWLQR 764
Query: 716 TGLVVLLPHGYDGQGPEHSSGRLERFLQMSDDNPFVIPEMDSTLRKQIQECNWQIVNVTT 895
TG+V+ LPHGYDGQGPEHSS R+ER+LQ+ +++P P + L++Q Q+CN Q + VT
Sbjct: 765 TGIVLSLPHGYDGQGPEHSSARMERYLQLCNEDPREFPS-EEKLQRQHQDCNIQAIYVTK 823
Query: 896 PANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKKCVSNLSEFDDVKG 1033
P+ YFH LRR IHR FRKPL++ K+LLRH S + EFD+ G
Sbjct: 824 PSQYFHALRRNIHRQFRKPLVIFFSKSLLRHPAARSTIDEFDEKHG 869
>sp|Q9ULD0|OGDHL_HUMAN 2-oxoglutarate dehydrogenase-like, mitochondrial OS=Homo
sapiens GN=OGDHL PE=2 SV=3
Length = 1010
Score = 327 bits (836), Expect = 3e-088
Identities = 172/340 (50%), Positives = 227/340 (66%), Gaps = 10/340 (2%)
Frame = +2
Query: 17 LQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASKE-YIPQKRDWLASHWTGFKSPE 193
L+ Y +KL+ G VT ++ ++ K I E + SK+ I + WL S W GF + +
Sbjct: 524 LKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFFNVD 583
Query: 194 QISRIRN---TGVKPEILKNVGKAISTFP-ENFKPHRGVKRVYEQRAQMIESGEGIDWGL 361
+ TG+ ++L ++G S+ P E+FK H G+ R+ RA M ++ +DW L
Sbjct: 584 GEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGRADMTKN-RTVDWAL 642
Query: 362 GEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYC-PLDHLTMNQDPEMF 538
E +AF +L+ EG HVRLSGQDVERGTFSHRH VLHDQE C P++HL +Q P +
Sbjct: 643 AEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAP--Y 700
Query: 539 TVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQT 718
TV NSSLSE+GVLGFELGY+M +PN+LV+WEAQFGDF N AQ + DQFIS+G+AKW+R
Sbjct: 701 TVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHN 760
Query: 719 GLVVLLPHGYDGQGPEHSSGRLERFLQMSDDNPFVIPEMDSTLR-KQIQECNWQIVNVTT 895
G+V+LLPHG +G GPEHSS R ERFLQMS+D+ P Q+ +CNW +VN +T
Sbjct: 761 GIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLYDCNWIVVNCST 820
Query: 896 PANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKKCVSNLSE 1015
PANYFHVLRRQI FRKPLI+ PK+LLRH + S+ +
Sbjct: 821 PANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQ 860
>sp|Q68EW0|OGDHL_XENLA 2-oxoglutarate dehydrogenase-like, mitochondrial
OS=Xenopus laevis GN=ogdhl PE=2 SV=1
Length = 1018
Score = 324 bits (830), Expect = 1e-087
Identities = 175/353 (49%), Positives = 233/353 (66%), Gaps = 15/353 (4%)
Frame = +2
Query: 17 LQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASKE-YIPQKRDWLASHWTGF---- 181
L+ Y +K++ G VT ++ ++ K I E + SK+ I + WL S W GF
Sbjct: 532 LKKYADKMIAEGTVTLQEFEEEIAKYDRICEEAYARSKDKKILNIKHWLDSPWPGFFTLD 591
Query: 182 KSPEQISRIRNTGVKPEILKNVGKAISTFP-ENFKPHRGVKRVYEQRAQMIESGEGIDWG 358
P+ ++ TG+ ++L ++G S+ P ++FK H G+ R+ + R +M S +DW
Sbjct: 592 GEPKSMT-CPPTGIPEDMLSHIGAIASSVPLKDFKIHGGLSRILKSRLEMTNS-RTVDWA 649
Query: 359 LGEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYC-PLDHLTMNQDPEM 535
L E + F +L+ EG HVRLSGQDVERGTFSHRH VLHDQE C P++HL NQ P
Sbjct: 650 LAEYMTFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRWTCVPMNHLWPNQAP-- 707
Query: 536 FTVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQ 715
+TV NSSLSE+GVLGFELG++M +PN+LV+WEAQFGDF N AQ + DQFISSG+AKW+R
Sbjct: 708 YTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFYNTAQCIIDQFISSGQAKWVRH 767
Query: 716 TGLVVLLPHGYDGQGPEHSSGRLERFLQMSDDNPFVIPEMDSTLR-KQIQECNWQIVNVT 892
G+V+LLPHG +G GPEHSS R ERFLQMS+D+ PE Q+ +CNW +VN +
Sbjct: 768 NGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPEFTQDFDVSQLFDCNWIVVNCS 827
Query: 893 TPANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKKCVSNLSEFDDVKGHPGFDK 1051
PA+YFHVLRRQI FRKPLI+ PK+LLRH + S+ FDD+K F +
Sbjct: 828 NPASYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSS---FDDMKTGTNFQR 877
>sp|Q5R9L8|OGDHL_PONAB 2-oxoglutarate dehydrogenase-like, mitochondrial OS=Pongo
abelii GN=OGDHL PE=2 SV=2
Length = 1010
Score = 324 bits (828), Expect = 2e-087
Identities = 171/331 (51%), Positives = 223/331 (67%), Gaps = 10/331 (3%)
Frame = +2
Query: 17 LQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASKE-YIPQKRDWLASHWTGFKSPE 193
L+ Y +KL+ G VT ++ ++ K I E + SK+ I + WL S W GF + +
Sbjct: 524 LKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFFNVD 583
Query: 194 QISRIRN---TGVKPEILKNVGKAISTFP-ENFKPHRGVKRVYEQRAQMIESGEGIDWGL 361
+ TG+ ++L ++G S+ P E+FK H G+ R+ RA MI++ +DW L
Sbjct: 584 GEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGRADMIKN-RTVDWAL 642
Query: 362 GEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYC-PLDHLTMNQDPEMF 538
E +AF +L+ EG VRLSGQDVERGTFSHRH VLHDQE C P++HL +Q P +
Sbjct: 643 AEYMAFGSLLKEGIRVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAP--Y 700
Query: 539 TVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQT 718
TV NSSLSE+GVLGFELGY+M +PN+LV+WEAQFGDF N AQ + DQFIS+G+AKW+R
Sbjct: 701 TVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHN 760
Query: 719 GLVVLLPHGYDGQGPEHSSGRLERFLQMSDDNPFVIPEMDSTLR-KQIQECNWQIVNVTT 895
G+V+LLPHG +G GPEHSS R ERFLQMS+D+ P Q+ +CNW +VN +T
Sbjct: 761 GIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLYDCNWIVVNCST 820
Query: 896 PANYFHVLRRQIHRDFRKPLIVMAPKNLLRH 988
PANYFHVLRRQI FRKPLI+ PK+LLRH
Sbjct: 821 PANYFHVLRRQILLPFRKPLIIFTPKSLLRH 851
>sp|Q6P6Z8|ODO1_XENLA 2-oxoglutarate dehydrogenase, mitochondrial OS=Xenopus
laevis GN=ogdh PE=2 SV=1
Length = 1021
Score = 321 bits (822), Expect = 1e-086
Identities = 173/344 (50%), Positives = 228/344 (66%), Gaps = 13/344 (3%)
Frame = +2
Query: 17 LQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASK-EYIPQKRDWLASHWTGFKSPE 193
LQ Y E L+ G V + + ++ K I E F SK E I + WL S W GF + +
Sbjct: 536 LQKYAETLISQGVVNQLEYEEEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFTLD 595
Query: 194 QISR---IRNTGVKPEILKNVGKAISTFP-ENFKPHRGVKRVYEQRAQMIESGEGIDWGL 361
R +TG+ E L ++G S+ P E+F H G+ R+ + R +M+++ +DW L
Sbjct: 596 GQPRSMTCPSTGLTEEDLTHIGNVASSVPVEDFMIHGGLSRILKGRGEMVKN-RTVDWAL 654
Query: 362 GEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYC-PLDHLTMNQDPEMF 538
E +A +L+ EG H+RLSGQDVERGTFSHRH VLHDQ + C P++HL NQ P +
Sbjct: 655 AEYMALGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAP--Y 712
Query: 539 TVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQT 718
TV NSSLSE+GVLGFELG++M +PN+LV+WEAQFGDF N AQ + DQF+ G+AKW+RQ
Sbjct: 713 TVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFVCPGQAKWVRQN 772
Query: 719 GLVVLLPHGYDGQGPEHSSGRLERFLQMSDDNPFVIPEMDSTLR-KQIQECNWQIVNVTT 895
G+V+LLPHG +G GPEHSS R ERFLQM +D+P V P+ Q+ +CNW +VN +T
Sbjct: 773 GIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVWPKASEDFAVGQLYDCNWIVVNCST 832
Query: 896 PANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKKCVSNLSEFDDV 1027
PAN+FHV+RRQI FRKPLIV PK+LLRH + S FDD+
Sbjct: 833 PANFFHVIRRQILLPFRKPLIVFTPKSLLRHPEA---RSSFDDM 873
>sp|Q4UKI8|ODO1_RICFE 2-oxoglutarate dehydrogenase E1 component OS=Rickettsia
felis GN=sucA PE=3 SV=2
Length = 977
Score = 257 bits (654), Expect = 3e-067
Identities = 135/279 (48%), Positives = 190/279 (68%), Gaps = 14/279 (5%)
Frame = +2
Query: 2 SHPSSLQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASKEYIPQKRDWLASHWTGF 181
S P+ IY +L++SG + K++++ + L++EFE +K Y P+ +L W G
Sbjct: 522 SKPTPGNIYANELVKSGIIDNNYFAKLKEEFKAKLDKEFEQAKNYKPEAH-FLGGLWQG- 579
Query: 182 KSPEQISRIRN----TGVKPEILKNVGKAISTFPENFKPHRGVKRVYEQRAQMIESGEGI 349
ISRIR TGV + L+++G + P++F + + +++E R + S + I
Sbjct: 580 -----ISRIRTQAAITGVGKKTLQDLGTKLCEIPKDFAVNPKLVKLFEARKATLTSDQPI 634
Query: 350 DWGLGEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYCPLDHLTMNQDP 529
DW E LAFA+L+ EG ++RL+GQD RGTFSHRHSVLH+Q Y PL++L+ Q
Sbjct: 635 DWATAEQLAFASLLSEGTNIRLTGQDCGRGTFSHRHSVLHNQIDDTTYIPLNNLSKTQ-- 692
Query: 530 EMFTVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWL 709
+ V++S+LSE+ VLGFE GYS+ NP +LV+WEAQFGDFANGAQ++FDQFISS E KWL
Sbjct: 693 AKYEVADSNLSEYAVLGFEYGYSLANPKNLVLWEAQFGDFANGAQIIFDQFISSSETKWL 752
Query: 710 RQTGLVVLLPHGYDGQGPEHSSGRLERFLQM-SDDNPFV 823
R +GLVVLLPH ++GQGPEHSS RLERFLQ+ ++DN +V
Sbjct: 753 RMSGLVVLLPHAFEGQGPEHSSARLERFLQLAAEDNMYV 791
>sp|Q72PJ7|ODO1_LEPIC 2-oxoglutarate dehydrogenase E1 component OS=Leptospira
interrogans serogroup Icterohaemorrhagiae serovar copenhageni GN=sucA
PE=3 SV=1
Length = 920
Score = 256 bits (653), Expect = 4e-067
Identities = 126/268 (47%), Positives = 184/268 (68%), Gaps = 4/268 (1%)
Frame = +2
Query: 2 SHPSSLQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASKEY-IPQKRDWLASHWTG 178
+HP ++++Y+++L+E G + +EDID I+ L + F+ +KE + + D + W+
Sbjct: 464 NHPPTVKLYEKRLVEEGDIPQEDIDFIKNGSMHGLEDSFQRAKEQDVKIRVDTMQGVWSK 523
Query: 179 FKSPEQISRIRNTGVKPEILKNVGKAISTFPENFKPHRGVKRVYEQRAQMIESGEGIDWG 358
F S + + T + E + + +A+++ P+ F P+ + ++ + R +M E +DWG
Sbjct: 524 F-SKDSLDSEPATKLLAEQMHGIVQALTSVPQGFTPNSKLVKLLQSRKEMAEGKIPVDWG 582
Query: 359 LGEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYCPLDHLTMNQDPEMF 538
EAL+F +++ G +RLSGQD +RGTFSHRH+VL D T E+Y PL+H++ Q
Sbjct: 583 FAEALSFGSILESGFRIRLSGQDSQRGTFSHRHAVLVDTNTNEKYIPLNHISSKQ--AKA 640
Query: 539 TVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQT 718
+ NSSLSEF VLGFE GYS+ +PN+LV+WEAQFGDFAN AQV+FDQFISS E KW R +
Sbjct: 641 EIINSSLSEFSVLGFEYGYSLSDPNALVMWEAQFGDFANSAQVIFDQFISSSEVKWQRLS 700
Query: 719 GLVVLLPHGYDGQGPEHSSGRLERFLQM 802
GL++LLPHGY+GQGPEHSS RLERFLQ+
Sbjct: 701 GLIMLLPHGYEGQGPEHSSARLERFLQL 728
>sp|Q8F6S7|ODO1_LEPIN 2-oxoglutarate dehydrogenase E1 component OS=Leptospira
interrogans GN=sucA PE=3 SV=1
Length = 920
Score = 256 bits (653), Expect = 4e-067
Identities = 126/268 (47%), Positives = 184/268 (68%), Gaps = 4/268 (1%)
Frame = +2
Query: 2 SHPSSLQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASKEY-IPQKRDWLASHWTG 178
+HP ++++Y+++L+E G + +EDID I+ L + F+ +KE + + D + W+
Sbjct: 464 NHPPTVKLYEKRLVEEGDIPQEDIDFIKNGSMHGLEDSFQRAKEQDVKIRVDTMQGVWSK 523
Query: 179 FKSPEQISRIRNTGVKPEILKNVGKAISTFPENFKPHRGVKRVYEQRAQMIESGEGIDWG 358
F S + + T + E + + +A+++ P+ F P+ + ++ + R +M E +DWG
Sbjct: 524 F-SKDSLDSEPATKLLAEQMHGIVQALTSVPQGFTPNSKLVKLLQSRKEMAEGKIPVDWG 582
Query: 359 LGEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYCPLDHLTMNQDPEMF 538
EAL+F +++ G +RLSGQD +RGTFSHRH+VL D T E+Y PL+H++ Q
Sbjct: 583 FAEALSFGSILESGFRIRLSGQDSQRGTFSHRHAVLVDTNTNEKYIPLNHISSKQ--AKA 640
Query: 539 TVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQT 718
+ NSSLSEF VLGFE GYS+ +PN+LV+WEAQFGDFAN AQV+FDQFISS E KW R +
Sbjct: 641 EIINSSLSEFSVLGFEYGYSLSDPNALVMWEAQFGDFANSAQVIFDQFISSSEVKWQRLS 700
Query: 719 GLVVLLPHGYDGQGPEHSSGRLERFLQM 802
GL++LLPHGY+GQGPEHSS RLERFLQ+
Sbjct: 701 GLIMLLPHGYEGQGPEHSSARLERFLQL 728
>sp|Q65IH4|ODO1_BACLD 2-oxoglutarate dehydrogenase E1 component OS=Bacillus
licheniformis (strain DSM 13 / ATCC 14580) GN=odhA PE=3 SV=1
Length = 944
Score = 253 bits (645), Expect = 4e-066
Identities = 132/282 (46%), Positives = 183/282 (64%), Gaps = 12/282 (4%)
Frame = +2
Query: 5 HPSSLQIYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASKEYIPQKRDWLASHWTGFK 184
HP+ I+ EKL+ G V KE + KI+ V L E + +P K++ +
Sbjct: 485 HPTVKNIFAEKLIHKGIVDKETVGKIKDAVQKRLEEAYRK----VPAKKEDMTHE---IV 537
Query: 185 SPEQISR---IRNTGVKPEILKNVGKAISTFPENFKPHRGVKRVYEQRAQMIESGEGIDW 355
PE +S +T V E L+ + + + ++PENF +KR+ E+RA+ E +DW
Sbjct: 538 LPEPVSNGFPDVDTSVDFETLRKINQELVSWPENFNVFDKLKRILERRAKAFEDDRKVDW 597
Query: 356 GLGEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYCPLDHLTMNQDPEM 535
L EA+AFA+++ +G +RL+GQD ERGTF+HR+ VLHD +TG+E+ L HL
Sbjct: 598 SLAEAMAFASILKDGTPLRLTGQDSERGTFAHRNLVLHDSKTGDEFIALHHLA--DTKAS 655
Query: 536 FTVSNSSLSEFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQ 715
F V NS LSE VLGFE GY++ +P ++VIWEAQFGDFAN AQV FDQFIS+G AKW ++
Sbjct: 656 FAVHNSPLSEGSVLGFEYGYNVSSPETMVIWEAQFGDFANAAQVYFDQFISAGRAKWGQK 715
Query: 716 TGLVVLLPHGYDGQGPEHSSGRLERFLQMSDDNPFVIPEMDS 841
+GLVVLLPHGY+GQGPEHSSGR ERFLQ++ +N + + + S
Sbjct: 716 SGLVVLLPHGYEGQGPEHSSGRTERFLQLAAENNWTVANLTS 757
>sp|Q1RHI4|ODO1_RICBR 2-oxoglutarate dehydrogenase E1 component OS=Rickettsia
bellii (strain RML369-C) GN=sucA PE=3 SV=1
Length = 927
Score = 250 bits (638), Expect = 2e-065
Identities = 125/268 (46%), Positives = 185/268 (69%), Gaps = 6/268 (2%)
Frame = +2
Query: 23 IYQEKLLESGQVTKEDIDKIQKKVSSILNEEFEASKEYIPQKRDWLASHWTGFKSPEQIS 202
IY +L++SG + K++++ + L++E+E +K Y Q+ +L W G +
Sbjct: 478 IYANELVKSGVIDNNYFAKLKEQFKAKLDKEYEQAKNY-KQEAHFLGGLWQGITRTR--T 534
Query: 203 RIRNTGVKPEILKNVGKAISTFPENFKPHRGVKRVYEQRAQMIESGEGIDWGLGEALAFA 382
++ TGV + L+++G + P++F + + ++++ R + + + IDW E LAFA
Sbjct: 535 QVAVTGVDKKTLQSLGTKLCEMPKDFAVNPKLVKLFDARKAALTADQPIDWATAEQLAFA 594
Query: 383 TLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEEYCPLDHLTMNQDPEMFTVSNSSLS 562
+L+ G ++RL+GQD RGTFSHRHSVLH+Q Y PL++L+ Q + V++S+LS
Sbjct: 595 SLLTSGTNIRLTGQDCGRGTFSHRHSVLHNQVDDTTYIPLNNLSKEQ--ATYEVADSNLS 652
Query: 563 EFGVLGFELGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQTGLVVLLPH 742
E+ VLGFE GYS+ NP +LV+WEAQFGDFANGAQ++FDQFISS E KWLR +GLVVLLPH
Sbjct: 653 EYAVLGFEYGYSLANPKNLVLWEAQFGDFANGAQIIFDQFISSSETKWLRMSGLVVLLPH 712
Query: 743 GYDGQGPEHSSGRLERFLQM-SDDNPFV 823
G++GQGPEHSS RLERFLQ+ ++DN +V
Sbjct: 713 GFEGQGPEHSSARLERFLQLAAEDNMYV 740
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,414,502,248
Number of Sequences: 518415
Number of Extensions: 42414502248
Number of Successful Extensions: 312188416
Number of sequences better than 0.0: 0
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