BLASTX 7.6.2
Query= UN10512 /QuerySize=1023
(1022 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9BTZ2|DHRS4_HUMAN Dehydrogenase/reductase SDR family member ... 226 3e-058
sp|Q5RCF8|DHRS4_PONAB Dehydrogenase/reductase SDR family member ... 225 5e-058
sp|Q8WNV7|DHRS4_PIG Dehydrogenase/reductase SDR family member 4 ... 216 3e-055
sp|Q9GKX2|DHRS4_RABIT Dehydrogenase/reductase SDR family member ... 215 4e-055
sp|Q99LB2|DHRS4_MOUSE Dehydrogenase/reductase SDR family member ... 215 5e-055
sp|Q13268|DHRS2_HUMAN Dehydrogenase/reductase SDR family member ... 213 3e-054
sp|Q8VID1|DHRS4_RAT Dehydrogenase/reductase SDR family member 4 ... 213 3e-054
sp|Q8SPU8|DHRS4_BOVIN Dehydrogenase/reductase SDR family member ... 210 2e-053
sp|P0CG22|DR4L1_HUMAN Putative dehydrogenase/reductase SDR famil... 187 2e-046
sp|Q6PKH6|DR4L2_HUMAN Dehydrogenase/reductase SDR family member ... 156 2e-037
sp|O07575|YHDF_BACSU Uncharacterized oxidoreductase yhdF OS=Baci... 126 4e-028
sp|P0AET9|HDHA_ECO57 7-alpha-hydroxysteroid dehydrogenase OS=Esc... 119 3e-026
sp|P0AET8|HDHA_ECOLI 7-alpha-hydroxysteroid dehydrogenase OS=Esc... 119 3e-026
sp|P16542|DHK1_STRVN Granaticin polyketide synthase putative ket... 92 4e-018
sp|Q5HJP2|BUTA_STAAC Acetoin(diacetyl) reductase OS=Staphylococc... 91 1e-017
sp|Q56318|Y019_THEMA Uncharacterized oxidoreductase TM_0019 OS=T... 87 2e-016
sp|P42317|YXJF_BACSU Uncharacterized oxidoreductase yxjF OS=Baci... 87 2e-016
sp|Q9LTV6|DECR2_ARATH Peroxisomal 2,4-dienoyl-CoA reductase OS=A... 75 9e-013
>sp|Q9BTZ2|DHRS4_HUMAN Dehydrogenase/reductase SDR family member 4 OS=Homo
sapiens GN=DHRS4 PE=1 SV=2
Length = 260
Score = 226 bits (574), Expect = 3e-058
Identities = 123/249 (49%), Positives = 160/249 (64%), Gaps = 3/249 (1%)
Frame = -3
Query: 918 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 739
L KVA+VTAST GIGF I R +GA VVVSSRKQ NV++AV L+ +G+ G VCH
Sbjct: 12 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 71
Query: 738 VSNAQHRRNLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 559
V A+ R LV V+ +G IDILV NAA NP I+ E V DK +INVK+ L+
Sbjct: 72 VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMT 131
Query: 558 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 388
+ + P +EK G SV+ ++SIA F P + Y V+KTALLGLTK LA E+ P + RVN
Sbjct: 132 KAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNC 191
Query: 387 VAPGFVPTHFASFITGNSQVRESIEEKTLLNRLGTTGDMAAATAFLASDDSSYITGETLV 208
+APG + T F+ + + + ES++E + RLG D A +FL S+D+SYITGET+V
Sbjct: 192 LAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVV 251
Query: 207 VAGGMPSRL 181
V GG PSRL
Sbjct: 252 VGGGTPSRL 260
>sp|Q5RCF8|DHRS4_PONAB Dehydrogenase/reductase SDR family member 4 OS=Pongo
abelii GN=DHRS4 PE=2 SV=2
Length = 260
Score = 225 bits (572), Expect = 5e-058
Identities = 122/249 (48%), Positives = 160/249 (64%), Gaps = 3/249 (1%)
Frame = -3
Query: 918 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 739
L KVA+VTAST GIGF I R +GA VVVSSRKQ NV++AV L+ +G+ G VCH
Sbjct: 12 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 71
Query: 738 VSNAQHRRNLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 559
V A+ R LV V+ +G IDILV NAA NP ++ E V DK +INVK+ L+
Sbjct: 72 VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMT 131
Query: 558 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 388
+ + P +EK G SV+ ++SIA F P + Y V+KTALLGLTK LA E+ P + RVN
Sbjct: 132 KAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNC 191
Query: 387 VAPGFVPTHFASFITGNSQVRESIEEKTLLNRLGTTGDMAAATAFLASDDSSYITGETLV 208
+APG + T F+ + + + ES++E + RLG D A +FL S+D+SYITGET+V
Sbjct: 192 LAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVV 251
Query: 207 VAGGMPSRL 181
V GG PSRL
Sbjct: 252 VGGGTPSRL 260
>sp|Q8WNV7|DHRS4_PIG Dehydrogenase/reductase SDR family member 4 OS=Sus scrofa
GN=DHRS4 PE=1 SV=1
Length = 260
Score = 216 bits (548), Expect = 3e-055
Identities = 115/249 (46%), Positives = 158/249 (63%), Gaps = 3/249 (1%)
Frame = -3
Query: 918 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 739
LE KVA+VTAST GIG I R +GA VVVSSRKQ NV+ V L+ +G+ G VCH
Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCH 71
Query: 738 VSNAQHRRNLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 559
V A+ R LV V +G +DILV NAA NP I+ E V DK+ +NVK+++L+
Sbjct: 72 VGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMT 131
Query: 558 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 388
+ + P +EK G SV+ ++S+ + P ++ Y V+KTALLGLTK LA E+ P + RVN
Sbjct: 132 KAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNC 191
Query: 387 VAPGFVPTHFASFITGNSQVRESIEEKTLLNRLGTTGDMAAATAFLASDDSSYITGETLV 208
+APG + T+F+ + + +E ++E + RLG D A +FL S+D+SYITGET+V
Sbjct: 192 LAPGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASYITGETVV 251
Query: 207 VAGGMPSRL 181
V GG SRL
Sbjct: 252 VGGGTASRL 260
>sp|Q9GKX2|DHRS4_RABIT Dehydrogenase/reductase SDR family member 4
OS=Oryctolagus cuniculus GN=DHRS4 PE=1 SV=1
Length = 260
Score = 215 bits (547), Expect = 4e-055
Identities = 118/249 (47%), Positives = 157/249 (63%), Gaps = 3/249 (1%)
Frame = -3
Query: 918 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 739
L KVAIVTAST GIG I R +GA VV+SSRKQ NV+ AV L+++G+ G VCH
Sbjct: 12 LANKVAIVTASTDGIGLAIARRLAQDGAHVVISSRKQQNVDRAVAALQAEGLSVTGTVCH 71
Query: 738 VSNAQHRRNLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 559
V A+ R LV + +G IDILV NAA NP ++ E V DK+ +INVK+ L+
Sbjct: 72 VGKAEDRERLVATALNLHGGIDILVSNAAVNPFFGKLMDVTEEVWDKILDINVKAMALMT 131
Query: 558 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEM-GPDTRVNA 388
+ + P +EK G SV+ + SIA F P + Y V+KTAL+GLTK LA E+ + RVN
Sbjct: 132 KAVVPEMEKRGGGSVVIVASIAAFNPFSGLGPYNVSKTALVGLTKNLALELAAQNIRVNC 191
Query: 387 VAPGFVPTHFASFITGNSQVRESIEEKTLLNRLGTTGDMAAATAFLASDDSSYITGETLV 208
+APG + T F+ + + E+I +K + RLG + A +FL S+D+SYITGET+V
Sbjct: 192 LAPGLIKTSFSKALWEDKAQEENIIQKLRIRRLGKPEECAGIVSFLCSEDASYITGETVV 251
Query: 207 VAGGMPSRL 181
VAGG PSRL
Sbjct: 252 VAGGAPSRL 260
>sp|Q99LB2|DHRS4_MOUSE Dehydrogenase/reductase SDR family member 4 OS=Mus
musculus GN=Dhrs4 PE=2 SV=1
Length = 260
Score = 215 bits (546), Expect = 5e-055
Identities = 117/249 (46%), Positives = 158/249 (63%), Gaps = 3/249 (1%)
Frame = -3
Query: 918 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 739
L KVA+VTAST GIGF I R +GA VVVSSRKQ NV+ AV L+ +G+ GIVCH
Sbjct: 12 LSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATLQGEGLSVTGIVCH 71
Query: 738 VSNAQHRRNLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 559
V A+ R L+ ++++ IDILV NAA NP ++ E V DK+ INV ++ +++
Sbjct: 72 VGKAEDREKLITTALKRHRGIDILVSNAAVNPFFGNLMDVTEEVWDKVLSINVTATAMMI 131
Query: 558 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 388
+ + P +EK G SV+ + S+AGF S+ Y V+KTALLGLTK AAE+ P + RVN
Sbjct: 132 KAVVPEMEKRGGGSVVIVGSVAGFTRFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNC 191
Query: 387 VAPGFVPTHFASFITGNSQVRESIEEKTLLNRLGTTGDMAAATAFLASDDSSYITGETLV 208
+APG + T F+S + + I+E + RLG D A +FL S+D+SYI GET+V
Sbjct: 192 LAPGLIKTRFSSVLWEEKAREDFIKEAMQIRRLGKPEDCAGIVSFLCSEDASYINGETVV 251
Query: 207 VAGGMPSRL 181
V GG PSRL
Sbjct: 252 VGGGTPSRL 260
>sp|Q13268|DHRS2_HUMAN Dehydrogenase/reductase SDR family member 2 OS=Homo
sapiens GN=DHRS2 PE=1 SV=3
Length = 258
Score = 213 bits (540), Expect = 3e-054
Identities = 109/242 (45%), Positives = 152/242 (62%), Gaps = 2/242 (0%)
Frame = -3
Query: 918 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 739
L +VA+VT ST GIGF I R +GA VV+SSRKQ NV+ A+ KL+ +G+ GIVCH
Sbjct: 12 LANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCH 71
Query: 738 VSNAQHRRNLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 559
V A+ R LV K ++ G +D LVC+A NP L T E + DK+ +NVKS LLL
Sbjct: 72 VGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLL 131
Query: 558 QDMAPHLE-KGSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNAV 385
+ P++E + +VI ++SIA + P ++ +Y V+KTALLGLT+ LA E+ P D RVN V
Sbjct: 132 SQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCV 191
Query: 384 APGFVPTHFASFITGNSQVRESIEEKTLLNRLGTTGDMAAATAFLASDDSSYITGETLVV 205
PG + T F+ GN + ++ +E L R+G + D A +FL S D+SY+ GE + V
Sbjct: 192 VPGIIKTDFSKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASYVNGENIAV 251
Query: 204 AG 199
AG
Sbjct: 252 AG 253
>sp|Q8VID1|DHRS4_RAT Dehydrogenase/reductase SDR family member 4 OS=Rattus
norvegicus GN=Dhrs4 PE=2 SV=1
Length = 260
Score = 213 bits (540), Expect = 3e-054
Identities = 116/249 (46%), Positives = 157/249 (63%), Gaps = 3/249 (1%)
Frame = -3
Query: 918 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 739
L KVA+VTAST GIG I R +GA VV+SSRKQ NV+ AV L+ +G+ G+VCH
Sbjct: 12 LANKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATLQGEGLSVTGVVCH 71
Query: 738 VSNAQHRRNLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 559
V A+ R LV ++ + IDILV NAA NP ++ E V +K+ INV +S +++
Sbjct: 72 VGKAEDREKLVNMALKLHQGIDILVSNAAVNPFFGNLMDVTEEVWNKVLSINVTASAMMI 131
Query: 558 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 388
+ + P +EK G SV+ ++S+AGF S+ Y V+KTALLGLTK AAE+ P + RVN
Sbjct: 132 KAVVPAMEKRGGGSVVIVSSVAGFVLFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNC 191
Query: 387 VAPGFVPTHFASFITGNSQVRESIEEKTLLNRLGTTGDMAAATAFLASDDSSYITGETLV 208
+APG + THF+S + E I+E + RLG D +FL S+D+SYI GET+V
Sbjct: 192 LAPGLIKTHFSSVLWKEKAREEMIKETMQIRRLGKPEDCVGIVSFLCSEDASYINGETVV 251
Query: 207 VAGGMPSRL 181
V GG PSRL
Sbjct: 252 VGGGTPSRL 260
>sp|Q8SPU8|DHRS4_BOVIN Dehydrogenase/reductase SDR family member 4 OS=Bos taurus
GN=DHRS4 PE=2 SV=1
Length = 260
Score = 210 bits (533), Expect = 2e-053
Identities = 114/249 (45%), Positives = 159/249 (63%), Gaps = 3/249 (1%)
Frame = -3
Query: 918 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 739
L+ KVA+VTAST GIGF I R +GA VVVSSRKQ NV+ AV LK +G+ G VCH
Sbjct: 12 LDNKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDRAVATLKGEGLSVTGTVCH 71
Query: 738 VSNAQHRRNLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 559
V A+ R LV V+ +G +DIL+ NAA +P ++ E V DK+ ++NVK++ LL
Sbjct: 72 VGKAEDRERLVATAVKLHGGVDILISNAAVSPFFGSLMDVPEEVWDKILDVNVKATALLT 131
Query: 558 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMG-PDTRVNA 388
+ + P + K G S++ ++SIA + P S+ Y V+KTALLGLTK LA E+ + RVN
Sbjct: 132 KAVVPEMAKRGGGSIVIVSSIAAYSPFPSLGPYNVSKTALLGLTKNLALELAESNVRVNC 191
Query: 387 VAPGFVPTHFASFITGNSQVRESIEEKTLLNRLGTTGDMAAATAFLASDDSSYITGETLV 208
+APG + T F+ + + +ESI+ + R+G + A +FL S+D+SYITGET+V
Sbjct: 192 LAPGLIRTSFSRVLWEDPARQESIKATFQIKRIGKPEECAGIVSFLCSEDASYITGETVV 251
Query: 207 VAGGMPSRL 181
VAGG S L
Sbjct: 252 VAGGSLSHL 260
>sp|P0CG22|DR4L1_HUMAN Putative dehydrogenase/reductase SDR family member 4-like
2 OS=Homo sapiens GN=DHRS4L1 PE=5 SV=1
Length = 281
Score = 187 bits (473), Expect = 2e-046
Identities = 106/252 (42%), Positives = 152/252 (60%), Gaps = 6/252 (2%)
Frame = -3
Query: 918 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 739
L KVA+VTAST IGF + +R +GA VVVS RKQ NV++AV L+ +G+ G VCH
Sbjct: 30 LTNKVALVTASTDWIGFAVAQRLAQDGAHVVVSRRKQQNVDQAVATLQGEGLSMTGTVCH 89
Query: 738 VSNAQHRRNLVEKTVQKYGKIDIL---VCNAAANPSTDPILSTKEAVLDKLWEINVKSSI 568
V + LV ++ +G IDIL + N+ +L T E D+ +IN K+
Sbjct: 90 VGKMKDWERLVATAMKLHGVIDILSLSITNSKRGLFWFTLLQTAEEAWDRNLDINGKALA 149
Query: 567 LLLQDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTR 397
L+++ + P +EK G SV F+ S+A F+P + Y V+KTALLGL K LA E+ P + R
Sbjct: 150 LMIKAVVPEMEKRGGGSVGFLASVAAFRPLPGFSPYNVSKTALLGLNKTLAIELAPRNIR 209
Query: 396 VNAVAPGFVPTHFASFITGNSQVRESIEEKTLLNRLGTTGDMAAATAFLASDDSSYITGE 217
VN +APG + T F+ + + + ES++E + RLG D +FL S+D+SY+TGE
Sbjct: 210 VNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDSLGIVSFLCSEDASYLTGE 269
Query: 216 TLVVAGGMPSRL 181
T++V GG PSRL
Sbjct: 270 TVMVGGGTPSRL 281
>sp|Q6PKH6|DR4L2_HUMAN Dehydrogenase/reductase SDR family member 4-like 2
OS=Homo sapiens GN=DHRS4L2 PE=2 SV=1
Length = 230
Score = 156 bits (394), Expect = 2e-037
Identities = 87/181 (48%), Positives = 113/181 (62%), Gaps = 3/181 (1%)
Frame = -3
Query: 918 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 739
L KVA+VTAST GIGF I R + A VVVSSRKQ NV++AV L+ +G+ G VCH
Sbjct: 28 LTNKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 87
Query: 738 VSNAQHRRNLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 559
V A+ R LV V+ +G IDILV NAA NP ++ E V DK +INVK+ L+
Sbjct: 88 VGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMT 147
Query: 558 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 388
+ + P +EK G SV+ ++SIA F P + Y V+KTALLGL LA E+ P + RVN
Sbjct: 148 KAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRVNC 207
Query: 387 V 385
+
Sbjct: 208 L 208
>sp|O07575|YHDF_BACSU Uncharacterized oxidoreductase yhdF OS=Bacillus subtilis
GN=yhdF PE=3 SV=1
Length = 289
Score = 126 bits (314), Expect = 4e-028
Identities = 80/244 (32%), Positives = 131/244 (53%), Gaps = 3/244 (1%)
Frame = -3
Query: 921 RLEGKVAIVTASTQGIGFGIIERFGLEGASV-VVSSRKQANVEEAVEKLKSKGIDAYGIV 745
+L+GKVAI+T GIG F EGA + ++ + ++ EE ++++ + + I
Sbjct: 42 KLKGKVAIITGGDSGIGRAAAIAFAKEGADISILYLDEHSDAEETRKRIEKENVRCLLIP 101
Query: 744 CHVSNAQHRRNLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSIL 565
V + H V++TV +GK+DILV NAA D IL+ L+K + N+ S
Sbjct: 102 GDVGDENHCEQAVQQTVDHFGKLDILVNNAAEQHPQDSILNISTEQLEKTFRTNIFSMFH 161
Query: 564 LLQDMAPHLEKGSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMG-PDTRVNA 388
+ + PHL++G ++I TSI ++ ++ Y TK A++ T+++A + RVNA
Sbjct: 162 MTKKALPHLQEGCAIINTTSITAYEGDTALIDYSSTKGAIVSFTRSMAKSLADKGIRVNA 221
Query: 387 VAPGFVPTHFASFITGNSQVRESIEEKTLLNRLGTTGDMAAATAFLASDDSSYITGETLV 208
VAPG + T +V++ + T + R G + A A LASD+SSY+TG+T+
Sbjct: 222 VAPGPIWTPLIPATFPEEKVKQHGLD-TPMGRPGQPVEHAGAYVLLASDESSYMTGQTIH 280
Query: 207 VAGG 196
V GG
Sbjct: 281 VNGG 284
>sp|P0AET9|HDHA_ECO57 7-alpha-hydroxysteroid dehydrogenase OS=Escherichia coli
O157:H7 GN=hdhA PE=3 SV=1
Length = 255
Score = 119 bits (298), Expect = 3e-026
Identities = 85/249 (34%), Positives = 130/249 (52%), Gaps = 14/249 (5%)
Frame = -3
Query: 921 RLEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVC 742
RL+GK AI+T + GIG I F GASVVVS V++++ G A+ C
Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67
Query: 741 HVSNAQHRRNLVEKTVQKYGKIDILVCNAAA---NPSTDPILSTKEAVLDKLWEINVKSS 571
+++ Q L + + K GK+DILV NA P P+ + A +E+NV S
Sbjct: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRA-----YELNVFSF 122
Query: 570 ILLLQDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMG-PDT 400
L Q +AP +EK G ++ ITS+A +M Y +K A L + +A ++G +
Sbjct: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182
Query: 399 RVNAVAPGFVPTH-FASFITGNSQVRESIEEKTLLNRLGTTGDMAAATAFLASDDSSYIT 223
RVN +APG + T S IT ++ + + + T + RLG D+A A FL S +S+++
Sbjct: 183 RVNGIAPGAILTDALKSVIT--PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240
Query: 222 GETLVVAGG 196
G+ L V+GG
Sbjct: 241 GQILTVSGG 249
>sp|P0AET8|HDHA_ECOLI 7-alpha-hydroxysteroid dehydrogenase OS=Escherichia coli
(strain K12) GN=hdhA PE=1 SV=1
Length = 255
Score = 119 bits (298), Expect = 3e-026
Identities = 85/249 (34%), Positives = 130/249 (52%), Gaps = 14/249 (5%)
Frame = -3
Query: 921 RLEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVC 742
RL+GK AI+T + GIG I F GASVVVS V++++ G A+ C
Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67
Query: 741 HVSNAQHRRNLVEKTVQKYGKIDILVCNAAA---NPSTDPILSTKEAVLDKLWEINVKSS 571
+++ Q L + + K GK+DILV NA P P+ + A +E+NV S
Sbjct: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRA-----YELNVFSF 122
Query: 570 ILLLQDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMG-PDT 400
L Q +AP +EK G ++ ITS+A +M Y +K A L + +A ++G +
Sbjct: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182
Query: 399 RVNAVAPGFVPTH-FASFITGNSQVRESIEEKTLLNRLGTTGDMAAATAFLASDDSSYIT 223
RVN +APG + T S IT ++ + + + T + RLG D+A A FL S +S+++
Sbjct: 183 RVNGIAPGAILTDALKSVIT--PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240
Query: 222 GETLVVAGG 196
G+ L V+GG
Sbjct: 241 GQILTVSGG 249
>sp|P16542|DHK1_STRVN Granaticin polyketide synthase putative ketoacyl reductase
1 OS=Streptomyces violaceoruber GN=gra-orf5 PE=3 SV=1
Length = 272
Score = 92 bits (228), Expect = 4e-018
Identities = 66/215 (30%), Positives = 101/215 (46%), Gaps = 14/215 (6%)
Frame = -3
Query: 906 VAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCHVSNA 727
VA+VT +T GIG I R GA + +R + + + V++L+ +G D G VC V++
Sbjct: 19 VALVTGATSGIGLAIARRLAALGARTFLCARDEERLAQTVKELRGEGFDVDGTVCDVADP 78
Query: 726 QHRRNLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLW----EINVKSSILLL 559
R V VQ+YG +DILV NA + + D+LW N+ S L+
Sbjct: 79 AQIRAYVAAAVQRYGTVDILVNNAGRSGG-----GATAEIADELWLDVITTNLTSVFLMT 133
Query: 558 QDM----APHLEKGSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMG-PDTRV 394
+++ +K +I I S G Q Y +K ++GLTKAL E+ V
Sbjct: 134 KEVLNAGGMLAKKRGRIINIASTGGKQGVVHAVPYSASKHGVVGLTKALGLELARTGITV 193
Query: 393 NAVAPGFVPTHFASFITGNSQVRESIEEKTLLNRL 289
NAV PGFV T A + + + E+ +R+
Sbjct: 194 NAVCPGFVETPMAERVREHYAGIWQVSEEETFDRI 228
>sp|Q5HJP2|BUTA_STAAC Acetoin(diacetyl) reductase OS=Staphylococcus aureus
(strain COL) GN=butA PE=3 SV=1
Length = 258
Score = 91 bits (224), Expect = 1e-017
Identities = 64/186 (34%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Frame = -3
Query: 909 KVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCHVSN 730
KVA+VT QGIGF I ER +G V V + + A KL S G A I VSN
Sbjct: 5 KVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSN 64
Query: 729 AQHRRNLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLLQDM 550
N V +T ++G ++V NA P+T PI + E ++ +NV + +Q
Sbjct: 65 RDDVFNAVRQTAAQFGDFHVMVNNAGLGPTT-PIDTITEEQFKTVYGVNVAGVLWGIQAA 123
Query: 549 APHLEK---GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGPD-TRVNAVA 382
+K G +I TS AG + +++Y TK A+ GLT+ A ++ + VNA A
Sbjct: 124 HEQFKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGITVNAFA 183
Query: 381 PGFVPT 364
PG V T
Sbjct: 184 PGIVQT 189
>sp|Q56318|Y019_THEMA Uncharacterized oxidoreductase TM_0019 OS=Thermotoga
maritima GN=TM_0019 PE=3 SV=2
Length = 256
Score = 87 bits (214), Expect = 2e-016
Identities = 59/188 (31%), Positives = 94/188 (50%), Gaps = 4/188 (2%)
Frame = -3
Query: 918 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 739
LEGKVA+VT QGIG I + F G VV++ + E E L+ +G+D +
Sbjct: 2 LEGKVAVVTGGGQGIGAAIAQLFAENGMKVVIAEIDEEAGVEREEMLRERGLDVTFVKTD 61
Query: 738 VSNAQHRRNLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 559
V++ +N+V KTV+ YG +D+LV NAA S I +++ +N+ +
Sbjct: 62 VADENSVKNMVRKTVEIYGGVDVLVNNAAV-MSVKSIFERPLEEWERVIRVNLTGPYICS 120
Query: 558 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 388
+ A + K G +I I S FQ + Y +K L+ LT +LA + RV +
Sbjct: 121 RYCAEEMIKRGGGVIINIASTRAFQSEPDTEPYSASKGGLVALTHSLAVSLSRYHIRVVS 180
Query: 387 VAPGFVPT 364
++PG++ T
Sbjct: 181 ISPGWIET 188
>sp|P42317|YXJF_BACSU Uncharacterized oxidoreductase yxjF OS=Bacillus subtilis
GN=yxjF PE=3 SV=2
Length = 257
Score = 87 bits (213), Expect = 2e-016
Identities = 60/185 (32%), Positives = 92/185 (49%), Gaps = 4/185 (2%)
Frame = -3
Query: 909 KVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCHVSN 730
+VA+VT + GIGF I F EGASV+VS + E+A KL +G DA I V+
Sbjct: 4 QVALVTGAAGGIGFEIAREFAREGASVIVSDLRPEACEKAASKLAEEGFDAAAIPYDVTK 63
Query: 729 AQHRRNLVEKTVQKYGKIDILVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLLQDM 550
+ V ++YG++DILV NA PI ++L ++ + + + ++ +
Sbjct: 64 EAQVADTVNVIQKQYGRLDILVNNAGIQ-HVAPIEEFPTDTFEQLIKVMLTAPFIAMKHV 122
Query: 549 APHLEKG--SSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNAVAP 379
P ++K +I I S+ G + Y K ++GLTK A E P VNA+ P
Sbjct: 123 FPIMKKQQFGRIINIASVNGLVGFAGKSAYNSAKHGVIGLTKVGALEGAPHGITVNALCP 182
Query: 378 GFVPT 364
G+V T
Sbjct: 183 GYVDT 187
>sp|Q9LTV6|DECR2_ARATH Peroxisomal 2,4-dienoyl-CoA reductase OS=Arabidopsis
thaliana GN=At3g12800 PE=2 SV=1
Length = 298
Score = 75 bits (182), Expect = 9e-013
Identities = 38/91 (41%), Positives = 56/91 (61%)
Frame = -3
Query: 918 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 739
+ G+VA++T GIGF I +FG GAS+ + R++ +++AV L+S GI A G+
Sbjct: 10 VRGQVALITGGGSGIGFEISSQFGKHGASIAIMGRRKQVLDDAVSALRSLGIQAIGLEGD 69
Query: 738 VSNAQHRRNLVEKTVQKYGKIDILVCNAAAN 646
V + R +VE T Q +GK+DILV AA N
Sbjct: 70 VRKQEDARRVVEATFQHFGKLDILVNAAAGN 100
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,414,502,248
Number of Sequences: 518415
Number of Extensions: 42414502248
Number of Successful Extensions: 312188416
Number of sequences better than 0.0: 0
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