BLASTX 7.6.2
Query= UN10521 /QuerySize=902
(901 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54ED4|GRWD1_DICDI Glutamate-rich WD repeat-containing protei... 255 5e-067
sp|Q9BQ67|GRWD1_HUMAN Glutamate-rich WD repeat-containing protei... 243 1e-063
sp|Q1JQD2|GRWD1_BOVIN Glutamate-rich WD repeat-containing protei... 243 2e-063
sp|Q810D6|GRWD1_MOUSE Glutamate-rich WD repeat-containing protei... 243 2e-063
sp|Q5XI13|GRWD1_RAT Glutamate-rich WD repeat-containing protein ... 242 4e-063
sp|Q9P783|RRB1_SCHPO Ribosome assembly protein rrb1 OS=Schizosac... 237 1e-061
sp|Q04225|RRB1_YEAST Ribosome assembly protein RRB1 OS=Saccharom... 198 4e-050
sp|Q59RH5|HAT2_CANAL Histone acetyltransferase type B subunit 2 ... 78 7e-014
sp|Q5KDT9|HAT2_CRYNE Histone acetyltransferase type B subunit 2 ... 64 1e-009
sp|A8QB65|WDR12_BRUMA Ribosome biogenesis protein WDR12 homolog ... 60 2e-008
sp|Q3MHL3|RBBP4_BOVIN Histone-binding protein RBBP4 OS=Bos tauru... 55 5e-007
sp|Q9W7I5|RBBP4_CHICK Histone-binding protein RBBP4 OS=Gallus ga... 55 5e-007
sp|Q6P3H7|RBBP4_DANRE Histone-binding protein RBBP4 OS=Danio rer... 55 5e-007
>sp|Q54ED4|GRWD1_DICDI Glutamate-rich WD repeat-containing protein 1
OS=Dictyostelium discoideum GN=grwd1 PE=3 SV=1
Length = 482
Score = 255 bits (649), Expect = 5e-067
Identities = 124/237 (52%), Positives = 158/237 (66%), Gaps = 6/237 (2%)
Frame = -1
Query: 898 HKDEGYAIDWSPATAGRLLSGDCMSMIHLWEPVSGSWTVDPIPLTGHTASVEDLQWSPAE 719
H EGYA+DWSP AGRL +GDC + I + +W D GHT SVED+QWSP+E
Sbjct: 249 HSIEGYALDWSPKIAGRLATGDCNNSIFVTNASESTWKTDTQAFKGHTESVEDIQWSPSE 308
Query: 718 ANVFASCSVDGTIALWDVRVGKTPALSFKAHNADVNVISWNRLASCMLASGSDDGAFSIH 539
VFASCS+D T+ +WD+R K PA++ KAH ADVNVISW+R +L SG DDG+F +
Sbjct: 309 EKVFASCSIDQTVRIWDIRKPK-PAITVKAHTADVNVISWSRNVEYLLVSGCDDGSFRVW 367
Query: 538 DLRVIKEGDAKVAHFEYHKHPITSIEWSAHESSTLAVSSGDNQLTIWDLSLEKDEEEEAE 359
DLR K+ ++ V+ F+YH PITSIEW+ +E S + VSS D+Q+TIWD SLE+D EE
Sbjct: 368 DLRAFKD-NSPVSDFKYHTGPITSIEWNPYEESQVIVSSSDDQVTIWDFSLEEDTEEFTN 426
Query: 358 FKAQTKEQVNTPQDLPPQLLFVHQGQKDLKELHWHNQIPGMIISTAEDGFNILMPYN 188
A + PPQL F+HQGQ D+KE+HWH QIP + IST+ DGFNI N
Sbjct: 427 ANANPDDDF----QYPPQLFFIHQGQHDIKEVHWHPQIPHVAISTSIDGFNIFKSSN 479
>sp|Q9BQ67|GRWD1_HUMAN Glutamate-rich WD repeat-containing protein 1 OS=Homo
sapiens GN=GRWD1 PE=1 SV=1
Length = 446
Score = 243 bits (620), Expect = 1e-063
Identities = 125/243 (51%), Positives = 153/243 (62%), Gaps = 12/243 (4%)
Frame = -1
Query: 901 GHKDEGYAIDWSPATAGRLLSGDCMSMIHLWEPV-SGSWTVDPIPLTGHTASVEDLQWSP 725
GH EG+A+DWSP GRLL+GDC IHLW P GSW VD P GHT SVEDLQWSP
Sbjct: 212 GHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSP 271
Query: 724 AEANVFASCSVDGTIALWDVRVGKTPA---LSFKAHNADVNVISWNRLASCMLASGSDDG 554
E VFASCS D +I +WD+R + A + AH+ DVNVISW+R +L SG DDG
Sbjct: 272 TENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLL-SGGDDG 330
Query: 553 AFSIHDLRVIKEGDAKVAHFEYHKHPITSIEWSAHESSTLAVSSGDNQLTIWDLSLEKDE 374
A I DLR K G + VA F+ H P+TS+EW +S A S D+Q+T WDL++E+D
Sbjct: 331 ALKIWDLRQFKSG-SPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLAVERDP 389
Query: 373 EEEAEFKAQTKEQVNTPQDLPPQLLFVHQGQKDLKELHWHNQIPGMIISTAEDGFNILMP 194
E A E DLP QLLFVHQG+ +LKELHWH Q PG+++STA GF I
Sbjct: 390 E------AGDVEADPGLADLPQQLLFVHQGETELKELHWHPQCPGLLVSTALSGFTIFRT 443
Query: 193 YNI 185
++
Sbjct: 444 ISV 446
>sp|Q1JQD2|GRWD1_BOVIN Glutamate-rich WD repeat-containing protein 1 OS=Bos
taurus GN=GRWD1 PE=2 SV=1
Length = 446
Score = 243 bits (618), Expect = 2e-063
Identities = 123/243 (50%), Positives = 152/243 (62%), Gaps = 12/243 (4%)
Frame = -1
Query: 901 GHKDEGYAIDWSPATAGRLLSGDCMSMIHLWEPV-SGSWTVDPIPLTGHTASVEDLQWSP 725
GH EG+A+DWSP GRLL+GDC IHLW P GSW VD P GHT SVEDLQWSP
Sbjct: 212 GHMGEGFALDWSPRVPGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSP 271
Query: 724 AEANVFASCSVDGTIALWDVRVGKTPA---LSFKAHNADVNVISWNRLASCMLASGSDDG 554
E VFASCS D +I +WD+R + A + AH+ DVNVI+W+ +L SG DDG
Sbjct: 272 TEDTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVINWSHREPFLL-SGGDDG 330
Query: 553 AFSIHDLRVIKEGDAKVAHFEYHKHPITSIEWSAHESSTLAVSSGDNQLTIWDLSLEKDE 374
A + DLR K G + VA F+ H P+TS+EW +S A S DNQ+T WDL++E+D
Sbjct: 331 ALKVWDLRQFKSG-SPVATFKQHVAPVTSVEWHPQDSGVFAASGADNQITQWDLAVERDP 389
Query: 373 EEEAEFKAQTKEQVNTPQDLPPQLLFVHQGQKDLKELHWHNQIPGMIISTAEDGFNILMP 194
E A E DLP QLLFVHQG+ DLKELHWH Q PG+++STA GF +
Sbjct: 390 E------AGDAETDPGLADLPQQLLFVHQGETDLKELHWHPQCPGVLVSTALSGFTVFRT 443
Query: 193 YNI 185
++
Sbjct: 444 ISV 446
>sp|Q810D6|GRWD1_MOUSE Glutamate-rich WD repeat-containing protein 1 OS=Mus
musculus GN=Grwd1 PE=2 SV=1
Length = 446
Score = 243 bits (618), Expect = 2e-063
Identities = 125/243 (51%), Positives = 154/243 (63%), Gaps = 12/243 (4%)
Frame = -1
Query: 901 GHKDEGYAIDWSPATAGRLLSGDCMSMIHLWEPV-SGSWTVDPIPLTGHTASVEDLQWSP 725
GH EG+A+DWSP GRLL+GDC +HLW P GSW VD P GHT SVEDLQWSP
Sbjct: 212 GHMGEGFALDWSPRVPGRLLTGDCQKNVHLWTPTEGGSWNVDQRPFVGHTRSVEDLQWSP 271
Query: 724 AEANVFASCSVDGTIALWDVRV--GKTPAL-SFKAHNADVNVISWNRLASCMLASGSDDG 554
E VFASCS D +I +WD+R GK L + AH+ DVNVISW+R +L SG DDG
Sbjct: 272 TEDTVFASCSADASIRIWDIRAAPGKACMLTTATAHDGDVNVISWSRREPFLL-SGGDDG 330
Query: 553 AFSIHDLRVIKEGDAKVAHFEYHKHPITSIEWSAHESSTLAVSSGDNQLTIWDLSLEKDE 374
A + DLR K G + VA F+ H P+TS+EW +S A S DNQ+T WDL++E+D
Sbjct: 331 ALKVWDLRQFKSG-SPVATFKQHMAPVTSVEWHPQDSGVFAASGADNQITQWDLAVERDP 389
Query: 373 EEEAEFKAQTKEQVNTPQDLPPQLLFVHQGQKDLKELHWHNQIPGMIISTAEDGFNILMP 194
E +T+ LP QLLFVHQG+ DLKELHWH Q PG++ISTA GF +
Sbjct: 390 E-----PGETETDPGLAA-LPQQLLFVHQGETDLKELHWHPQCPGVLISTALSGFTVFRT 443
Query: 193 YNI 185
++
Sbjct: 444 ISV 446
>sp|Q5XI13|GRWD1_RAT Glutamate-rich WD repeat-containing protein 1 OS=Rattus
norvegicus GN=Grwd1 PE=2 SV=1
Length = 445
Score = 242 bits (615), Expect = 4e-063
Identities = 125/243 (51%), Positives = 153/243 (62%), Gaps = 12/243 (4%)
Frame = -1
Query: 901 GHKDEGYAIDWSPATAGRLLSGDCMSMIHLWEPV-SGSWTVDPIPLTGHTASVEDLQWSP 725
GH EG+A+DWSP GRLL+GDC IHLW P GSW VD P GHT SVEDLQWSP
Sbjct: 211 GHMGEGFALDWSPRVPGRLLTGDCQKNIHLWTPTDGGSWNVDQRPFVGHTRSVEDLQWSP 270
Query: 724 AEANVFASCSVDGTIALWDVRV--GKTPAL-SFKAHNADVNVISWNRLASCMLASGSDDG 554
E VFASCS D +I +WD+R GK L + AH+ DVNVISW+R +L SG DDG
Sbjct: 271 TEDTVFASCSADASIRIWDIRAAPGKACMLTTAAAHDGDVNVISWSRREPFLL-SGGDDG 329
Query: 553 AFSIHDLRVIKEGDAKVAHFEYHKHPITSIEWSAHESSTLAVSSGDNQLTIWDLSLEKDE 374
+ DLR K G + VA F+ H P+TS+EW +S A S DNQ+T WDL++E+D
Sbjct: 330 TLKVWDLRQFKSG-SPVATFKQHVAPVTSVEWHPQDSGVFAASGADNQITQWDLAVERDP 388
Query: 373 EEEAEFKAQTKEQVNTPQDLPPQLLFVHQGQKDLKELHWHNQIPGMIISTAEDGFNILMP 194
E +T+ LP QLLFVHQG+ DLKELHWH Q PG++ISTA GF +
Sbjct: 389 E-----SGETETDPGLAA-LPQQLLFVHQGETDLKELHWHPQCPGVLISTALSGFTVFRT 442
Query: 193 YNI 185
++
Sbjct: 443 ISV 445
>sp|Q9P783|RRB1_SCHPO Ribosome assembly protein rrb1 OS=Schizosaccharomyces
pombe GN=rrb1 PE=1 SV=1
Length = 480
Score = 237 bits (603), Expect = 1e-061
Identities = 120/237 (50%), Positives = 156/237 (65%), Gaps = 12/237 (5%)
Frame = -1
Query: 898 HKDEGYAIDWSPATAGRLLSGDCMSMIHLWEPVSGSWTVDPIPLTGHTASVEDLQWSPAE 719
HK EGYA+DWSP LLSGD + I L + +G W D P HTA+VEDLQWSP+E
Sbjct: 245 HKTEGYALDWSPFEYS-LLSGDNANEIFLTKYSNGGWQTDSSPFLSHTAAVEDLQWSPSE 303
Query: 718 ANVFASCSVDGTIALWDVR-VGKTPALSFKAH-NADVNVISWNRLASCMLASGSDDGAFS 545
NVF+SCS DGT +WDVR KT AL+ AH DVNV+SWN +LA+G+D+G +S
Sbjct: 304 KNVFSSCSCDGTFRIWDVRNKQKTSALTVNAHPGVDVNVLSWNTRVPNLLATGADNGVWS 363
Query: 544 IHDLRVIKEGDA---KVAHFEYHKHPITSIEWSAHESSTLAVSSGDNQLTIWDLSLEKDE 374
+ DLR +K + VA F++H+ PI SIEW +E S + V DNQ+++WDLS+E DE
Sbjct: 364 VWDLRSLKSSSSVATPVASFKWHRAPIYSIEWHPNEDSVIGVVGADNQISLWDLSVELDE 423
Query: 373 EEEAEFKAQTKEQVNTPQDLPPQLLFVHQGQKDLKELHWHNQIPGMIISTAEDGFNI 203
EE Q QD+PPQL+F+H GQ+++KE+HWH QIPG I+STA G N+
Sbjct: 424 EE------QDSRAAEGLQDVPPQLMFIHMGQQEIKEMHWHRQIPGTIVSTAMTGINV 474
>sp|Q04225|RRB1_YEAST Ribosome assembly protein RRB1 OS=Saccharomyces cerevisiae
GN=RRB1 PE=1 SV=1
Length = 511
Score = 198 bits (503), Expect = 4e-050
Identities = 106/232 (45%), Positives = 145/232 (62%), Gaps = 12/232 (5%)
Frame = -1
Query: 877 IDWSP-ATAGRLLSGDCMSMIHLWEPVSGSWTVDPIPLT-GHTASVEDLQWSPAEANVFA 704
+DWSP G LLSGDC I+ + + W D P T + S+ED+QWS E+ VFA
Sbjct: 279 LDWSPLIKTGALLSGDCSGQIYFTQRHTSRWVTDKQPFTVSNNKSIEDIQWSRTESTVFA 338
Query: 703 SCSVDGTIALWDVRVGK-TPALSFKAHNADVNVISWNRLASCMLASGSDDGAFSIHDLRV 527
+ DG I +WD R K PA+S KA N DVNVISW+ +LASG D+G + + DLR
Sbjct: 339 TAGCDGYIRIWDTRSKKHKPAISVKASNTDVNVISWSDKIGYLLASGDDNGTWGVWDLRQ 398
Query: 526 IKEGDA----KVAHFEYHKHPITSIEWSAHESSTLAVSSGDNQLTIWDLSLEKDEEEEAE 359
+A VA +++HK ITSI ++ + S +AV S DN +T+WDLS+E D+EE +
Sbjct: 399 FTPSNADAVQPVAQYDFHKGAITSIAFNPLDESIVAVGSEDNTVTLWDLSVEADDEEIKQ 458
Query: 358 FKAQTKEQVNTPQDLPPQLLFVHQGQKDLKELHWHNQIPGMIISTAEDGFNI 203
A+TKE Q++PPQLLFVH QK++K++ WH QIPG ++ST DG N+
Sbjct: 459 QAAETKEL----QEIPPQLLFVH-WQKEVKDVKWHKQIPGCLVSTGTDGLNV 505
>sp|Q59RH5|HAT2_CANAL Histone acetyltransferase type B subunit 2 OS=Candida
albicans GN=HAT2 PE=3 SV=1
Length = 382
Score = 78 bits (191), Expect = 7e-014
Identities = 48/182 (26%), Positives = 85/182 (46%), Gaps = 5/182 (2%)
Frame = -1
Query: 898 HKDEGYAIDWSPATAGRLLSGDCMSMIHLWEPVSGSWTVDPIPLTGHTASVEDLQWSPAE 719
H GY + W+P G L++G + + + + + T V D++W
Sbjct: 142 HTKNGYGLSWNPKQKGLLVTGADDNFVCVTDTTTNKTT---FKSDIQKDIVNDVKWHQFN 198
Query: 718 ANVFASCSVDGTIALWDVRVGKTPALSFKAHNADVNVISWNRLASCMLASGSDDGAFSIH 539
N+FAS S D + L+D R K + + + +N ++++ A ++A G+ ++
Sbjct: 199 GNLFASVSEDSHVYLFDARDNKVVSQYYAESSNGINSLAFSPFAENLVAIGNTSSNINLL 258
Query: 538 DLRVIKEGDAKVAHFEYHKHPITSIEWSAHESSTLAVSSGDNQLTIWDLSL--EKDEEEE 365
DLR + E + H IT +E+S H LA S D ++ IWDL E+ ++E+
Sbjct: 259 DLRKLGENSGLLHTMMGHSEGITCMEFSPHHDGILATGSQDRRIIIWDLFKVGEEQQQED 318
Query: 364 AE 359
AE
Sbjct: 319 AE 320
>sp|Q5KDT9|HAT2_CRYNE Histone acetyltransferase type B subunit 2 OS=Cryptococcus
neoformans GN=HAT2 PE=3 SV=1
Length = 435
Score = 64 bits (155), Expect = 1e-009
Identities = 39/126 (30%), Positives = 57/126 (45%)
Frame = -1
Query: 901 GHKDEGYAIDWSPATAGRLLSGDCMSMIHLWEPVSGSWTVDPIPLTGHTASVEDLQWSPA 722
GH ++W P S I +W+ S + + GH A + + ++P+
Sbjct: 238 GHSAYVADVEWHPKNENMFGSVSDDGQIMIWDTRSDNTAKASSQVQGHNAEINCISFAPS 297
Query: 721 EANVFASCSVDGTIALWDVRVGKTPALSFKAHNADVNVISWNRLASCMLASGSDDGAFSI 542
+F + S D TIALWD+R T SF+AH DV +SW+ + AS S D I
Sbjct: 298 SEYLFLTGSSDNTIALWDLRKLSTKHHSFEAHTNDVLQLSWSPTSPVHFASASADRRVHI 357
Query: 541 HDLRVI 524
DL I
Sbjct: 358 WDLDAI 363
>sp|A8QB65|WDR12_BRUMA Ribosome biogenesis protein WDR12 homolog OS=Brugia
malayi GN=Bm1_47965 PE=3 SV=1
Length = 433
Score = 60 bits (144), Expect = 2e-008
Identities = 29/101 (28%), Positives = 50/101 (49%), Gaps = 2/101 (1%)
Frame = -1
Query: 859 TAGRLLSGDCMSMIHLWEPVSGSWTVDPIPLTGHTASVEDLQWSPAEANVFASCSVDGTI 680
++G L++G ++ LW+P S T+ GH + + W+ + N+F S S D T+
Sbjct: 325 SSGMLITGSVDPVVRLWDPRSHEGTLVKQSFIGHCGWISSVFWNKVKENLFISASFDKTV 384
Query: 679 ALWDVRVGKTPALSFKAHNADVNVISWNRLASCMLASGSDD 557
+WDVR KTP H+ + W+ + ++ SG D
Sbjct: 385 KMWDVRSNKTPLYDLVGHSDRILCCDWS--VNELIVSGGVD 423
>sp|Q3MHL3|RBBP4_BOVIN Histone-binding protein RBBP4 OS=Bos taurus GN=RBBP4 PE=1
SV=3
Length = 425
Score = 55 bits (132), Expect = 5e-007
Identities = 30/99 (30%), Positives = 50/99 (50%)
Frame = -1
Query: 814 LWEPVSGSWTVDPIPLTGHTASVEDLQWSPAEANVFASCSVDGTIALWDVRVGKTPALSF 635
+W+ S + + + HTA V L ++P + A+ S D T+ALWD+R K SF
Sbjct: 254 IWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSF 313
Query: 634 KAHNADVNVISWNRLASCMLASGSDDGAFSIHDLRVIKE 518
++H ++ + W+ +LAS D ++ DL I E
Sbjct: 314 ESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGE 352
>sp|Q9W7I5|RBBP4_CHICK Histone-binding protein RBBP4 OS=Gallus gallus GN=RBBP4
PE=1 SV=3
Length = 425
Score = 55 bits (132), Expect = 5e-007
Identities = 30/99 (30%), Positives = 50/99 (50%)
Frame = -1
Query: 814 LWEPVSGSWTVDPIPLTGHTASVEDLQWSPAEANVFASCSVDGTIALWDVRVGKTPALSF 635
+W+ S + + + HTA V L ++P + A+ S D T+ALWD+R K SF
Sbjct: 254 IWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSF 313
Query: 634 KAHNADVNVISWNRLASCMLASGSDDGAFSIHDLRVIKE 518
++H ++ + W+ +LAS D ++ DL I E
Sbjct: 314 ESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGE 352
>sp|Q6P3H7|RBBP4_DANRE Histone-binding protein RBBP4 OS=Danio rerio GN=rbbp4
PE=2 SV=3
Length = 424
Score = 55 bits (132), Expect = 5e-007
Identities = 30/99 (30%), Positives = 50/99 (50%)
Frame = -1
Query: 814 LWEPVSGSWTVDPIPLTGHTASVEDLQWSPAEANVFASCSVDGTIALWDVRVGKTPALSF 635
+W+ S + + + HTA V L ++P + A+ S D T+ALWD+R K SF
Sbjct: 254 IWDTRSNNTSKPSHAVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSF 313
Query: 634 KAHNADVNVISWNRLASCMLASGSDDGAFSIHDLRVIKE 518
++H ++ + W+ +LAS D ++ DL I E
Sbjct: 314 ESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGE 352
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,414,502,248
Number of Sequences: 518415
Number of Extensions: 42414502248
Number of Successful Extensions: 312188416
Number of sequences better than 0.0: 0
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