BLASTX 7.6.2
Query= UN10556 /QuerySize=1347
(1346 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q39227|SMT2_ARATH 24-methylenesterol C-methyltransferase 2 OS... 692 2e-198
sp|Q94JS4|SMT3B_ARATH 24-methylenesterol C-methyltransferase 3 O... 632 2e-180
sp|O82427|SMT2_ORYSJ 24-methylenesterol C-methyltransferase 2 OS... 531 5e-150
sp|Q6ZIX2|SMT1_ORYSJ Cycloartenol-C-24-methyltransferase 1 OS=Or... 237 1e-061
sp|Q9LM02|SMT1_ARATH Cycloartenol-C-24-methyltransferase OS=Arab... 236 3e-061
sp|Q54I98|SMT1_DICDI Probable cycloartenol-C-24-methyltransferas... 226 3e-058
sp|Q6C2D9|ERG6_YARLI Sterol 24-C-methyltransferase OS=Yarrowia l... 220 3e-056
sp|Q6BRB7|ERG6_DEBHA Sterol 24-C-methyltransferase OS=Debaryomyc... 218 1e-055
sp|Q6FRZ7|ERG6_CANGA Sterol 24-C-methyltransferase OS=Candida gl... 215 1e-054
sp|O14321|ERG6_SCHPO Sterol 24-C-methyltransferase OS=Schizosacc... 213 2e-054
sp|Q96WX4|ERG6_PNECA Sterol 24-C-methyltransferase OS=Pneumocyst... 213 3e-054
sp|Q6CYB3|ERG6_KLULA Sterol 24-C-methyltransferase OS=Kluyveromy... 213 4e-054
sp|O74198|ERG6_CANAL Sterol 24-C-methyltransferase OS=Candida al... 212 5e-054
sp|Q5EN22|ERG6_MAGGR Sterol 24-C-methyltransferase OS=Magnaporth... 211 9e-054
sp|Q875K1|ERG6_CLAL4 Sterol 24-C-methyltransferase OS=Clavispora... 211 1e-053
sp|P25087|ERG6_YEAST Sterol 24-C-methyltransferase OS=Saccharomy... 211 1e-053
sp|Q9P3R1|ERG6_NEUCR Sterol 24-C-methyltransferase OS=Neurospora... 201 9e-051
sp|Q759S7|ERG6_ASHGO Sterol 24-C-methyltransferase OS=Ashbya gos... 197 2e-049
sp|Q9C6B9|PEAM3_ARATH Putative phosphoethanolamine N-methyltrans... 73 5e-012
sp|Q9ZSK1|GTOMC_ARATH Tocopherol O-methyltransferase, chloroplas... 72 6e-012
>sp|Q39227|SMT2_ARATH 24-methylenesterol C-methyltransferase 2 OS=Arabidopsis
thaliana GN=SMT2 PE=1 SV=2
Length = 361
Score = 692 bits (1784), Expect = 2e-198
Identities = 332/356 (93%), Positives = 345/356 (96%)
Frame = +1
Query: 112 MDSVALFFTGALVAGGIYWFLCVLGPAERKGKRALDLSGGSISAEKVQDNYKQYWSFFRR 291
MDS+ LFFTGALVA GIYWFLCVLGPAERKGKRA+DLSGGSISAEKVQDNYKQYWSFFRR
Sbjct: 1 MDSLTLFFTGALVAVGIYWFLCVLGPAERKGKRAVDLSGGSISAEKVQDNYKQYWSFFRR 60
Query: 292 PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQ 471
PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSI GKSH+DATRLHEEMAVDLIQ
Sbjct: 61 PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIPGKSHKDATRLHEEMAVDLIQ 120
Query: 472 VKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCG 651
VKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQV RAR HN+KAGLDALCEVVCG
Sbjct: 121 VKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVNRARLHNKKAGLDALCEVVCG 180
Query: 652 NFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAEDE 831
NFLQMPFDDN+FDGAYSIEATCHAPKLEEVYAEIYRVLKPGS+YVSYEWVTT+KF AED+
Sbjct: 181 NFLQMPFDDNSFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSMYVSYEWVTTEKFKAEDD 240
Query: 832 EHVEVIQGIERGDALPGLRAYSDIAEAAKKVGFEVVKEKDLAAPPAEPWWTRLKMGRLAY 1011
EHVEVIQGIERGDALPGLRAY DIAE AKKVGFE+VKEKDLA+PPAEPWWTRLKMGRLAY
Sbjct: 241 EHVEVIQGIERGDALPGLRAYVDIAETAKKVGFEIVKEKDLASPPAEPWWTRLKMGRLAY 300
Query: 1012 WRNHIVVQVLSAVGVAPKGTVDVHEMLFKTADFLSRGGETEIFSPMHMIFCRKPIS 1179
WRNHIVVQ+LSAVGVAPKGTVDVHEMLFKTAD+L+RGGET IFSPMHMI CRKP S
Sbjct: 301 WRNHIVVQILSAVGVAPKGTVDVHEMLFKTADYLTRGGETGIFSPMHMILCRKPES 356
>sp|Q94JS4|SMT3B_ARATH 24-methylenesterol C-methyltransferase 3 OS=Arabidopsis
thaliana GN=SMT3 PE=2 SV=1
Length = 359
Score = 632 bits (1630), Expect = 2e-180
Identities = 292/354 (82%), Positives = 330/354 (93%)
Frame = +1
Query: 112 MDSVALFFTGALVAGGIYWFLCVLGPAERKGKRALDLSGGSISAEKVQDNYKQYWSFFRR 291
MDSVAL+ T L+AG +YWF+CVLGPAERKGKRA DLSGGSISAEKV+DNY QYWSFFR+
Sbjct: 1 MDSVALYCTAGLIAGAVYWFICVLGPAERKGKRASDLSGGSISAEKVKDNYNQYWSFFRK 60
Query: 292 PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQ 471
PKEIE+AEKVPDFVDTFYNLVTDIYEWGWGQSFHFSP + GKS +DATR+HEEMAVDLI+
Sbjct: 61 PKEIESAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPHVPGKSDKDATRIHEEMAVDLIK 120
Query: 472 VKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCG 651
VKPGQKILD GCGVGGPMRAIA+HS+A V GITINEYQV+RA+ HN+KAGLD+LC VVCG
Sbjct: 121 VKPGQKILDAGCGVGGPMRAIAAHSKAQVTGITINEYQVQRAKLHNKKAGLDSLCNVVCG 180
Query: 652 NFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAEDE 831
NFL+MPFD+NTFDGAYSIEATCHAPKLEEVY+EI+RV+KPGSL+VSYEWVTT+K+ +DE
Sbjct: 181 NFLKMPFDENTFDGAYSIEATCHAPKLEEVYSEIFRVMKPGSLFVSYEWVTTEKYRDDDE 240
Query: 832 EHVEVIQGIERGDALPGLRAYSDIAEAAKKVGFEVVKEKDLAAPPAEPWWTRLKMGRLAY 1011
EH +VIQGIERGDALPGLR+Y+DIA AKKVGFEVVKEKDLA PP++PWW RLKMGR+AY
Sbjct: 241 EHKDVIQGIERGDALPGLRSYADIAVTAKKVGFEVVKEKDLAKPPSKPWWNRLKMGRIAY 300
Query: 1012 WRNHIVVQVLSAVGVAPKGTVDVHEMLFKTADFLSRGGETEIFSPMHMIFCRKP 1173
WRNH+VV +LSA+GVAPKGTVDVH+MLFKTAD+L+RGGET IFSPMHMI CRKP
Sbjct: 301 WRNHVVVVILSAIGVAPKGTVDVHKMLFKTADYLTRGGETGIFSPMHMILCRKP 354
>sp|O82427|SMT2_ORYSJ 24-methylenesterol C-methyltransferase 2 OS=Oryza sativa
subsp. japonica GN=Smt2-1 PE=2 SV=2
Length = 363
Score = 531 bits (1367), Expect = 5e-150
Identities = 251/360 (69%), Positives = 297/360 (82%), Gaps = 5/360 (1%)
Frame = +1
Query: 112 MDSVALFFTGALVAGG-IYWFLCVLGPAERKGKRALDLSGGSISAEKVQDNYKQYWSFFR 288
M++ + +T A V +YWF+ V+G AE KGKRA+DL GSI+ +KV+D Y QYWSFFR
Sbjct: 1 MEAATMAWTAAGVGMALVYWFVWVMGAAEVKGKRAVDLKMGSITNDKVKDKYTQYWSFFR 60
Query: 289 RPKEIET----AEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMA 456
RPKE T AEKVP FVDTFYNLVTDIYEWGWGQSFHFSPS+ G+SHR+ATR+HEE
Sbjct: 61 RPKETATTEASAEKVPAFVDTFYNLVTDIYEWGWGQSFHFSPSLPGRSHREATRVHEERV 120
Query: 457 VDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALC 636
DL+Q KPG ++LDVGCGVGGPMRAIA+HS +NVVGITINEYQV RAR HNRKAGLD+ C
Sbjct: 121 ADLLQAKPGHRLLDVGCGVGGPMRAIAAHSGSNVVGITINEYQVNRARAHNRKAGLDSRC 180
Query: 637 EVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKF 816
EVVCGNFL MPF D +FDGAYSIEATCHAP+L++VY E++RVLKPG LYVSYEWVTT +
Sbjct: 181 EVVCGNFLSMPFSDASFDGAYSIEATCHAPRLQDVYGEVFRVLKPGGLYVSYEWVTTSLY 240
Query: 817 NAEDEEHVEVIQGIERGDALPGLRAYSDIAEAAKKVGFEVVKEKDLAAPPAEPWWTRLKM 996
A++ EHVE I GIERGDALPGLR +IA AK+VGFEV+KE DLA PPA PWWTRLKM
Sbjct: 241 RADNPEHVEAIHGIERGDALPGLRRQDEIASIAKEVGFEVLKELDLALPPALPWWTRLKM 300
Query: 997 GRLAYWRNHIVVQVLSAVGVAPKGTVDVHEMLFKTADFLSRGGETEIFSPMHMIFCRKPI 1176
GR+AYWRN +VV+VL+ + +APKG +VHEML++TA L+RGGET IF+PMHM+ RKP+
Sbjct: 301 GRIAYWRNSLVVRVLTMLRIAPKGVCEVHEMLYETAQHLTRGGETGIFTPMHMVLLRKPV 360
>sp|Q6ZIX2|SMT1_ORYSJ Cycloartenol-C-24-methyltransferase 1 OS=Oryza sativa
subsp. japonica GN=Smt1-1 PE=2 SV=1
Length = 344
Score = 237 bits (604), Expect = 1e-061
Identities = 118/272 (43%), Positives = 165/272 (60%), Gaps = 7/272 (2%)
Frame = +1
Query: 211 ALDLS---GGSISAEKVQ---DNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEW 372
A+DL+ GG I+ ++V+ D Y++Y ++ KE D V+ +Y+L T YE+
Sbjct: 6 AMDLASGLGGKITKDEVKSAVDEYEKYHGYY-GGKEEARKSNYTDMVNKYYDLATSFYEY 64
Query: 373 GWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRA 552
GWG+SFHF+ G+S R++ + HE + VKPG K+LDVGCG+GGP+R IA S A
Sbjct: 65 GWGESFHFAHRWNGESLRESIKRHEHFLALQLGVKPGMKVLDVGCGIGGPLREIAKFSLA 124
Query: 553 NVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKL 732
+V G+ NEYQ+ R ++ NR AG+ C+ V +F++MPF DNTFD Y+IEATCHAP
Sbjct: 125 SVTGLNNNEYQITRGKELNRVAGVSGTCDFVKADFMKMPFSDNTFDAVYAIEATCHAPDP 184
Query: 733 EEVYAEIYRVLKPGSLYVSYEWVTTDKFNAEDEEHVEVIQGIERGDALPGLRAYSDIAEA 912
Y EIYRVLKPG + YEW TD + + H + IE G+ LP +R+ +A
Sbjct: 185 VGCYKEIYRVLKPGQCFAVYEWCITDHYEPNNATHKRIKDEIELGNGLPDIRSTQQCLQA 244
Query: 913 AKKVGFEVVKEKDLAAPPAEPWWTRLKMGRLA 1008
AK GFEV+ +KDLA PW+ L R +
Sbjct: 245 AKDAGFEVIWDKDLAEDSPVPWYLPLDPSRFS 276
>sp|Q9LM02|SMT1_ARATH Cycloartenol-C-24-methyltransferase OS=Arabidopsis
thaliana GN=SMT1 PE=2 SV=1
Length = 336
Score = 236 bits (602), Expect = 3e-061
Identities = 116/258 (44%), Positives = 159/258 (61%), Gaps = 4/258 (1%)
Frame = +1
Query: 226 GGSISAEKV---QDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHF 396
GG I V + Y+QY F E E D V+ +Y+L T YE+GWG+SFHF
Sbjct: 8 GGKIDKSDVLTAVEKYEQY-HVFHGGNEEERKANYTDMVNKYYDLATSFYEYGWGESFHF 66
Query: 397 SPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVVGITIN 576
+ +G+S R++ + HE + ++PGQK+LDVGCG+GGP+R IA S + V G+ N
Sbjct: 67 AQRWKGESLRESIKRHEHFLALQLGIQPGQKVLDVGCGIGGPLREIARFSNSVVTGLNNN 126
Query: 577 EYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIY 756
EYQ+ R ++ NR AG+D C V +F++MPF +N+FD Y+IEATCHAP Y EIY
Sbjct: 127 EYQITRGKELNRLAGVDKTCNFVKADFMKMPFPENSFDAVYAIEATCHAPDAYGCYKEIY 186
Query: 757 RVLKPGSLYVSYEWVTTDKFNAEDEEHVEVIQGIERGDALPGLRAYSDIAEAAKKVGFEV 936
RVLKPG + +YEW TD F+ ++ EH ++ IE GD LP +R + EA K+ GFEV
Sbjct: 187 RVLKPGQCFAAYEWCMTDAFDPDNAEHQKIKGEIEIGDGLPDIRLTTKCLEALKQAGFEV 246
Query: 937 VKEKDLAAPPAEPWWTRL 990
+ EKDLA PW+ L
Sbjct: 247 IWEKDLAKDSPVPWYLPL 264
>sp|Q54I98|SMT1_DICDI Probable cycloartenol-C-24-methyltransferase 1
OS=Dictyostelium discoideum GN=smt1 PE=1 SV=1
Length = 354
Score = 226 bits (575), Expect = 3e-058
Identities = 113/255 (44%), Positives = 155/255 (60%), Gaps = 3/255 (1%)
Frame = +1
Query: 244 EKVQDNYKQYWSFFR--RPKEIETAE-KVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRG 414
+KV D Y F+ K I+ + V+TFY+L TD YE+GWGQSFHF+ +
Sbjct: 30 DKVDDTLNGYKELFKGNDDKAIQARKNNYTHMVNTFYDLATDFYEFGWGQSFHFATRHKY 89
Query: 415 KSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKR 594
+S + HE + + PG K++D+GCGVGGPMR IA S ANVVG+ NEYQ++R
Sbjct: 90 ESFEASIARHEMYMAHQLGLFPGMKVIDIGCGVGGPMRTIARFSGANVVGLNNNEYQIQR 149
Query: 595 ARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPG 774
+ N AGL LC + +F+ +P +DNT+D AY IEATCHAP L +Y E++R++KPG
Sbjct: 150 GKRLNESAGLSHLCSFIKADFMHVPVEDNTYDCAYQIEATCHAPDLVGLYKEVFRIVKPG 209
Query: 775 SLYVSYEWVTTDKFNAEDEEHVEVIQGIERGDALPGLRAYSDIAEAAKKVGFEVVKEKDL 954
L+ YEW+ T+KFN ED V + + IE G+ LP L ++I AAK GFEV+ D+
Sbjct: 210 GLFGGYEWIMTNKFNPEDPVEVNIKKQIELGNGLPDLVKPAEIINAAKAAGFEVITAFDV 269
Query: 955 AAPPAEPWWTRLKMG 999
A PW+ L G
Sbjct: 270 AETSELPWYLPLSSG 284
>sp|Q6C2D9|ERG6_YARLI Sterol 24-C-methyltransferase OS=Yarrowia lipolytica
GN=ERG6 PE=3 SV=1
Length = 381
Score = 220 bits (558), Expect = 3e-056
Identities = 104/215 (48%), Positives = 144/215 (66%), Gaps = 1/215 (0%)
Frame = +1
Query: 340 FYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGG 519
+YNLVTD YE+GWG SFHFS +G++ R AT HE + ++PG K+LDVGCGVGG
Sbjct: 82 YYNLVTDFYEYGWGSSFHFSRYYKGEAFRQATARHEHYLAYKMGIQPGMKVLDVGCGVGG 141
Query: 520 PMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAY 699
P R IA + AN+VG+ N+YQV+R ++ G V G+F+QM F DN+FD Y
Sbjct: 142 PAREIARFTGANIVGLNNNDYQVERGTHYSEVQGFGDQVTYVKGDFMQMDFPDNSFDAVY 201
Query: 700 SIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAEDEEHVEVIQGIERGDALP 879
+IEAT HAP LE VY+EI+RVLKPG ++ YEWV TD+++ + EH ++ GIE+GD +P
Sbjct: 202 AIEATVHAPVLEGVYSEIFRVLKPGGVFGVYEWVMTDEYDESNPEHRDICYGIEKGDGIP 261
Query: 880 GLRAYSDIAEAAKKVGFEVVKEKDLAAPPAE-PWW 981
+ +A + VGF++ ++DLAA AE PW+
Sbjct: 262 KMYKREVAVKALENVGFDIEYQEDLAADDAEVPWY 296
>sp|Q6BRB7|ERG6_DEBHA Sterol 24-C-methyltransferase OS=Debaryomyces hansenii
GN=ERG6 PE=3 SV=1
Length = 377
Score = 218 bits (553), Expect = 1e-055
Identities = 113/265 (42%), Positives = 159/265 (60%), Gaps = 3/265 (1%)
Frame = +1
Query: 193 ERKGKRALDLSGGSISAEKVQDNYKQYW-SFFRRPKEIETAEKVPDFVDTFYNLVTDIYE 369
++ G +AL +S ++E D Y ++W + E + + +YNLVTD YE
Sbjct: 28 KQTGLKAL-MSKARDASEVANDGYFKHWDGGVTKEDEDKRLSDYSNLTAHYYNLVTDFYE 86
Query: 370 WGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSR 549
+GWG SFHFS G++ R AT HE +Q+ K+LDVGCGVGGP R I +
Sbjct: 87 YGWGSSFHFSRYYTGEAFRQATARHEHFLAHKMQINENMKVLDVGCGVGGPAREICRFTD 146
Query: 550 ANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPK 729
++VG+ N+YQ++RA + RK LD V G+F+QM F+ +FD Y+IEAT HAP
Sbjct: 147 CSIVGLNNNDYQIERANHYARKYKLDDKLSFVKGDFMQMDFEAESFDAVYAIEATVHAPV 206
Query: 730 LEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAEDEEHVEVIQGIERGDALPGLRAYSDIAE 909
LE VY+EIY+VLKPG ++ YEWV TDK++ E+EEH ++ GIE GD +P + +
Sbjct: 207 LEGVYSEIYKVLKPGGVFGVYEWVMTDKYDDENEEHRKIAYGIEVGDGIPKMYKREVAEK 266
Query: 910 AAKKVGFEVVKEKDLAAPPAE-PWW 981
A K VGFE+ E DLA + PW+
Sbjct: 267 ALKSVGFEIEYEADLADKEDDIPWY 291
>sp|Q6FRZ7|ERG6_CANGA Sterol 24-C-methyltransferase OS=Candida glabrata GN=ERG6
PE=3 SV=1
Length = 372
Score = 215 bits (545), Expect = 1e-054
Identities = 112/269 (41%), Positives = 159/269 (59%), Gaps = 5/269 (1%)
Frame = +1
Query: 184 GPAERKGKRALDLSGGSISAEKVQDNYKQYWSFFRRPKEIE--TAEKVPDFVDTFYNLVT 357
G R G AL LS + + Y ++W + KE E E + ++YN+VT
Sbjct: 21 GAESRTGLTAL-LSKNRNAQREAVSKYLRHWD-GKTDKEAEDRRLEDYNEATHSYYNVVT 78
Query: 358 DIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIA 537
D YE+GWG SFHFS +G++ + A HE+ + +K G +LDVGCGVGGP R IA
Sbjct: 79 DFYEYGWGSSFHFSRFYKGENFQAAMARHEQYLAYMAGIKKGDLVLDVGCGVGGPARTIA 138
Query: 538 SHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATC 717
+ N++G+ N+YQ+++A+ + +K L + V G+F+ M F+ N+FD Y+IEATC
Sbjct: 139 RFTGCNIIGLNNNDYQIQKAKYYAKKYNLQDHMDFVKGDFMNMEFEPNSFDKVYAIEATC 198
Query: 718 HAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAEDEEHVEVIQGIERGDALPGLRAYS 897
HAPKLE VY EIY+VLKPG + YEWV T+ ++ +EEH ++ IE GD +P +
Sbjct: 199 HAPKLEGVYGEIYKVLKPGGTFAVYEWVMTENYDENNEEHRKIAYEIELGDGIPKMFTVD 258
Query: 898 DIAEAAKKVGFEVVKEKDLAAPPAE-PWW 981
+A K VGFEV KDLA E PW+
Sbjct: 259 VAKQALKNVGFEVEVSKDLADEDDEIPWY 287
>sp|O14321|ERG6_SCHPO Sterol 24-C-methyltransferase OS=Schizosaccharomyces pombe
GN=SPBC16E9.05 PE=2 SV=1
Length = 378
Score = 213 bits (542), Expect = 2e-054
Identities = 113/273 (41%), Positives = 160/273 (58%), Gaps = 13/273 (4%)
Frame = +1
Query: 202 GKRALDLSGGSISAEKVQD----NYKQYWSFFRRPKEIETAEK-------VPDFVDTFYN 348
GK A +G + A K D ++Y+ F+ R E E+ E V+++Y+
Sbjct: 21 GKAAEKKTGLAAIASKDVDEQSRKLQEYFEFWDRNHENESEEDRARRIDGYKSVVNSYYD 80
Query: 349 LVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMR 528
L TD+YE+GW QSFHFS +G++ + HE + +KPG ++LDVGCGVGGP R
Sbjct: 81 LATDLYEYGWSQSFHFSRFYKGEAFAQSIARHEHYLAYRMGIKPGSRVLDVGCGVGGPAR 140
Query: 529 AIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIE 708
I + N+VG+ N+YQ+ R ++ K LD V G+F+ MPF+DNTFD Y+IE
Sbjct: 141 EITEFTGCNLVGLNNNDYQISRCNNYAVKRNLDKKQVFVKGDFMHMPFEDNTFDYVYAIE 200
Query: 709 ATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAEDEEHVEVIQGIERGDALPGLR 888
AT HAP LE VY EI+RVLKPG ++ YEWV +D +++ +H E+ IE GD +P +
Sbjct: 201 ATVHAPSLEGVYGEIFRVLKPGGVFGVYEWVMSDDYDSSIPKHREIAYNIEVGDGIPQMV 260
Query: 889 AYSDIAEAAKKVGFEVVKEKDLA--APPAEPWW 981
D EA KKVGF +++E DL P PW+
Sbjct: 261 RKCDAVEAIKKVGFNLLEEDDLTDHDNPDLPWY 293
>sp|Q96WX4|ERG6_PNECA Sterol 24-C-methyltransferase OS=Pneumocystis carinii
GN=erg6 PE=2 SV=1
Length = 377
Score = 213 bits (541), Expect = 3e-054
Identities = 103/241 (42%), Positives = 154/241 (63%), Gaps = 3/241 (1%)
Frame = +1
Query: 340 FYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGG 519
+YNLVTD YE+GW SFHF + +S A HE ++ G+ +LDVGCGVGG
Sbjct: 80 YYNLVTDFYEYGWSTSFHFCRFAKDESFSQAIARHEHYIALHAGIREGETVLDVGCGVGG 139
Query: 520 PMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAY 699
P I+ + AN+VG+ N+YQ++RA+ ++ K GL + + G+F+QMPF +N+FD Y
Sbjct: 140 PACQISVFTGANIVGLNNNDYQIQRAKYYSEKKGLSDKLKFIKGDFMQMPFPENSFDKIY 199
Query: 700 SIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAEDEEHVEVIQGIERGDALP 879
SIEAT HAP LE VY+EIYRVLKPG LY SYEWV +K++ D EH +++ GIE GD++P
Sbjct: 200 SIEATIHAPSLEGVYSEIYRVLKPGGLYASYEWVMLNKYDENDPEHQQIVYGIEIGDSIP 259
Query: 880 GLRAYSDIAEAAKKVGFEVVKEKDLAAPPAE-PWWTRL--KMGRLAYWRNHIVVQVLSAV 1050
+ + A KVGFE++ ++L+ + PW+ L + ++ +R+ I + ++ +
Sbjct: 260 KISKIGEAEAALIKVGFEIIHSEELSTKNSPLPWYYYLDGDLRKVRSFRDFISIARMTTI 319
Query: 1051 G 1053
G
Sbjct: 320 G 320
>sp|Q6CYB3|ERG6_KLULA Sterol 24-C-methyltransferase OS=Kluyveromyces lactis
GN=ERG6 PE=3 SV=1
Length = 371
Score = 213 bits (540), Expect = 4e-054
Identities = 108/266 (40%), Positives = 152/266 (57%), Gaps = 1/266 (0%)
Frame = +1
Query: 196 RKGKRALDLSGGSISAEKVQDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEWG 375
+ G AL S E V K + E E + ++YN+VTD YE+G
Sbjct: 25 KSGFSALVSKNKSAQTEAVAKYLKHWDGKTDADAERRRLEDYNESTHSYYNVVTDFYEYG 84
Query: 376 WGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRAN 555
WG SFHFS +G+S + HE +K ILDVGCGVGGP R I+ + N
Sbjct: 85 WGSSFHFSRFFKGESFSASVARHEHYLAYKAGIKENDLILDVGCGVGGPARTISRFTGCN 144
Query: 556 VVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLE 735
++G+ N+YQ+++A + ++ LD+ V G+F++M FD+NTFD Y+IEATCHAP E
Sbjct: 145 IIGLNNNDYQIQKANYYAKRDHLDSKLSFVKGDFMKMEFDENTFDSVYAIEATCHAPTFE 204
Query: 736 EVYAEIYRVLKPGSLYVSYEWVTTDKFNAEDEEHVEVIQGIERGDALPGLRAYSDIAEAA 915
VY EIY+VLKPG + YEWV TDK++ + EH ++ IE GD +P + + +A
Sbjct: 205 GVYGEIYKVLKPGGTFAVYEWVMTDKYDETNPEHRKIAYEIELGDGIPKMYSVDAARDAL 264
Query: 916 KKVGFEVVKEKDLAAPPAE-PWWTRL 990
KVGFE+++E DLA E PW+ L
Sbjct: 265 SKVGFEILEENDLADNDDEIPWYAPL 290
>sp|O74198|ERG6_CANAL Sterol 24-C-methyltransferase OS=Candida albicans GN=ERG6
PE=3 SV=1
Length = 376
Score = 212 bits (539), Expect = 5e-054
Identities = 107/264 (40%), Positives = 153/264 (57%), Gaps = 1/264 (0%)
Frame = +1
Query: 193 ERKGKRALDLSGGSISAEKVQDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEW 372
++ G AL ++ + +K + + E + +YNLVTD YE+
Sbjct: 27 KKTGLSALIAKSKDAASVAAEGYFKHWDGGISKDDEEKRLNDYSQLTHHYYNLVTDFYEY 86
Query: 373 GWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRA 552
GWG SFHFS +G++ R AT HE + + K+LDVGCGVGGP R I +
Sbjct: 87 GWGSSFHFSRYYKGEAFRQATARHEHFLAHKMNLNENMKVLDVGCGVGGPGREITRFTDC 146
Query: 553 NVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKL 732
+VG+ N+YQ++RA + +K LD V G+F+QM F+ +FD Y+IEAT HAP L
Sbjct: 147 EIVGLNNNDYQIERANHYAKKYHLDHKLSYVKGDFMQMDFEPESFDAVYAIEATVHAPVL 206
Query: 733 EEVYAEIYRVLKPGSLYVSYEWVTTDKFNAEDEEHVEVIQGIERGDALPGLRAYSDIAEA 912
E VY+EIY+VLKPG ++ YEWV TDK++ +EEH ++ GIE GD +P + + +A
Sbjct: 207 EGVYSEIYKVLKPGGIFGVYEWVMTDKYDETNEEHRKIAYGIEVGDGIPKMYSRKVAEQA 266
Query: 913 AKKVGFEVVKEKDLAAPPAE-PWW 981
K VGFE+ +KDLA E PW+
Sbjct: 267 LKNVGFEIEYQKDLADVDDEIPWY 290
>sp|Q5EN22|ERG6_MAGGR Sterol 24-C-methyltransferase OS=Magnaporthe grisea
GN=ERG6 PE=2 SV=2
Length = 390
Score = 211 bits (537), Expect = 9e-054
Identities = 119/289 (41%), Positives = 161/289 (55%), Gaps = 14/289 (4%)
Frame = +1
Query: 256 DNYKQYWSFFRRPKEIETA----EKVPDFVD---TFYNLVTDIYEWGWGQSFHFSPSIRG 414
D Y ++W + + ET E+ D+ +YNLVTD YE+GWGQSFHF G
Sbjct: 55 DQYFRHWD--GKTAKTETTKVREERKADYATLTRQYYNLVTDFYEYGWGQSFHFCTFAPG 112
Query: 415 KSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKR 594
++ A +E I +K G K+LD+GCGVGGP R IA + AN+ GITINEYQV+R
Sbjct: 113 ETFASAITRYEHTLAHRIGIKKGMKVLDIGCGVGGPARQIAKFTGANITGITINEYQVER 172
Query: 595 ARDHNRKAGLDA--LCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLK 768
AR + G A + V G+F+ +PF+ TFD YSIEAT HAPKLE+VY +I+ VLK
Sbjct: 173 ARRYAEMEGYGAGEQLKFVQGDFMALPFEKETFDAVYSIEATVHAPKLEDVYKQIFNVLK 232
Query: 769 PGSLYVSYEWVTTDKFNAEDEEHVEVIQGIERGDALPGLRAYSDIAEAAKKVGFEVVKEK 948
PG ++ YEWV TD ++ D H E+ GIE G + L+ A K GFE+++ +
Sbjct: 233 PGGIFGLYEWVMTDAYDENDPHHKEIRFGIEHGGGIANLQTAQTAIAAIKAAGFELLESE 292
Query: 949 DLA-APPAEPWWTRLKMGRLAYWRNHIVVQVLSAVGVAPKGTVDVHEML 1092
DLA PW+ L G A+ +LS + P G H +L
Sbjct: 293 DLADNSDRAPWYWPL--GGNAWQYASTFGDILSTFTMTPAGRAIAHTVL 339
>sp|Q875K1|ERG6_CLAL4 Sterol 24-C-methyltransferase OS=Clavispora lusitaniae
(strain ATCC 42720) GN=ERG6 PE=3 SV=1
Length = 375
Score = 211 bits (536), Expect = 1e-053
Identities = 108/264 (40%), Positives = 152/264 (57%), Gaps = 1/264 (0%)
Frame = +1
Query: 193 ERKGKRALDLSGGSISAEKVQDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEW 372
+++G AL S +K + E + + +YNLVTD YE+
Sbjct: 27 KKRGISALMAKAKEASDVATNGYFKHWDGGVSEDDEKKRLDDYSSLTKNYYNLVTDFYEY 86
Query: 373 GWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRA 552
GWG SFHFS +G++ R AT HE + + ++LDVGCGVGGP R I +
Sbjct: 87 GWGSSFHFSRYYKGEAFRQATARHEHFLAHKMNINENMRVLDVGCGVGGPGREICRFTDC 146
Query: 553 NVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKL 732
+VG+ N+YQV+RA+ + +K LD V G+F+QM F+ +FD Y+IEAT HAP L
Sbjct: 147 TIVGLNNNDYQVERAQYYAKKYKLDDKLSYVKGDFMQMDFEPESFDAVYAIEATVHAPVL 206
Query: 733 EEVYAEIYRVLKPGSLYVSYEWVTTDKFNAEDEEHVEVIQGIERGDALPGLRAYSDIAEA 912
E VY+EIY+VLKPG ++ YEWV TDK++ +EEH ++ GIE GD +P + +A
Sbjct: 207 EGVYSEIYKVLKPGGVFGVYEWVMTDKYDENNEEHRKIAYGIEVGDGIPKMYKREVAEQA 266
Query: 913 AKKVGFEVVKEKDLAAPPAE-PWW 981
K VGF++ EKDLA E PW+
Sbjct: 267 LKNVGFDIEYEKDLADVNDEIPWY 290
>sp|P25087|ERG6_YEAST Sterol 24-C-methyltransferase OS=Saccharomyces cerevisiae
GN=ERG6 PE=1 SV=4
Length = 383
Score = 211 bits (535), Expect = 1e-053
Identities = 112/277 (40%), Positives = 159/277 (57%), Gaps = 2/277 (0%)
Frame = +1
Query: 193 ERKGKRALDLSGGSISAEKVQDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEW 372
++ G AL S E VQ + + + E E + ++YN+VTD YE+
Sbjct: 24 KKTGLSALMSKNNSAQKEAVQKYLRNWDGRTDKDAEERRLEDYNEATHSYYNVVTDFYEY 83
Query: 373 GWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRA 552
GWG SFHFS +G+S + HE ++ G +LDVGCGVGGP R IA +
Sbjct: 84 GWGSSFHFSRFYKGESFAASIARHEHYLAYKAGIQRGDLVLDVGCGVGGPAREIARFTGC 143
Query: 553 NVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKL 732
NV+G+ N+YQ+ +A+ + +K L + V G+F++M F++NTFD Y+IEATCHAPKL
Sbjct: 144 NVIGLNNNDYQIAKAKYYAKKYNLSDQMDFVKGDFMKMDFEENTFDKVYAIEATCHAPKL 203
Query: 733 EEVYAEIYRVLKPGSLYVSYEWVTTDKFNAEDEEHVEVIQGIERGDALPGLRAYSDIAEA 912
E VY+EIY+VLKPG + YEWV TDK++ + EH ++ IE GD +P + +A
Sbjct: 204 EGVYSEIYKVLKPGGTFAVYEWVMTDKYDENNPEHRKIAYEIELGDGIPKMFHVDVARKA 263
Query: 913 AKKVGFEVVKEKDLAAPPAE-PWWTRLKMGRLAYWRN 1020
K GFEV+ +DLA E PW+ L G Y +N
Sbjct: 264 LKNCGFEVLVSEDLADNDDEIPWYYPL-TGEWKYVQN 299
>sp|Q9P3R1|ERG6_NEUCR Sterol 24-C-methyltransferase OS=Neurospora crassa
GN=B24P7.240 PE=3 SV=1
Length = 379
Score = 201 bits (511), Expect = 9e-051
Identities = 103/230 (44%), Positives = 141/230 (61%), Gaps = 2/230 (0%)
Frame = +1
Query: 340 FYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGG 519
+YNL TDIYE+GWGQ FHF G+S A HE I +K K+LDVGCGVGG
Sbjct: 82 YYNLATDIYEYGWGQCFHFCRYSPGESFYQAIARHEHYLAAQIGIKKDMKVLDVGCGVGG 141
Query: 520 PMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAY 699
P R IA + A++ G+ N+YQ+ RA + + GL + V G+F+QM F DN+FD Y
Sbjct: 142 PAREIAKFTDAHITGLNNNDYQIDRATHYAVRDGLSGQLKFVKGDFMQMSFPDNSFDAVY 201
Query: 700 SIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAEDEEHVEVIQGIERGDALP 879
+IEAT HAPKLE VY EIYRVLKPG + YEW+ TD ++ ++ EH ++ IE G+ +
Sbjct: 202 AIEATVHAPKLEGVYGEIYRVLKPGGTFGVYEWLMTDNYDNDNVEHRDIRLAIEVGNGIS 261
Query: 880 GLRAYSDIAEAAKKVGFEVVKEKDLA-APPAEPWWTRLKMGRLAYWRNHI 1026
+ S+ A K VGFE+V +DLA PW+ + G L Y ++++
Sbjct: 262 NMVTISEGLAAMKNVGFELVHHEDLADRNDPMPWYWPI-AGELRYMQSYL 310
>sp|Q759S7|ERG6_ASHGO Sterol 24-C-methyltransferase OS=Ashbya gossypii GN=ERG6
PE=3 SV=1
Length = 373
Score = 197 bits (500), Expect = 2e-049
Identities = 109/277 (39%), Positives = 153/277 (55%), Gaps = 8/277 (2%)
Frame = +1
Query: 193 ERKGKRALDLSGGSISAEKVQDNYKQYWSFFRRPKEIETAEKVPDF---VDTFYNLVTDI 363
ER G AL L + ++ Y ++W + E ++ D+ ++YN+VTD
Sbjct: 25 ERSGLTAL-LGKNREAQQEAVAKYLRHWDGATDAEAEE--RRLADYNESTHSYYNVVTDF 81
Query: 364 YEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASH 543
YE+GWG SFHFS G+S + HE + G +LDVGCGVGGP R IA
Sbjct: 82 YEYGWGASFHFSRFYTGESFAMSMARHEHYLAHRAGITSGDLVLDVGCGVGGPAREIARF 141
Query: 544 SRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHA 723
+ VVG+ N+YQ+ + + ++RK GL V G+F+ M F D TFD Y+IEATCHA
Sbjct: 142 TGCRVVGLNNNDYQIMKGKHYSRKLGLGDQVSYVKGDFMNMDFPDATFDKVYAIEATCHA 201
Query: 724 PKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAEDEEHVEVIQGIERGDALPGLRAYSDI 903
P E VY EIYRVLKPG ++ YEWV T+ ++ + EH + IE GD +P + +
Sbjct: 202 PSFEGVYGEIYRVLKPGGVFAVYEWVMTENYDETNPEHRRIAYDIELGDGIPKMYSVKVA 261
Query: 904 AEAAKKVGFEVVKEKDLA-APPAEPWWTRLKMGRLAY 1011
+A KVGFE++ ++D A PW+ L G AY
Sbjct: 262 RDALAKVGFEILVDEDRADNDDPVPWYYPL-TGEWAY 297
>sp|Q9C6B9|PEAM3_ARATH Putative phosphoethanolamine N-methyltransferase 3
OS=Arabidopsis thaliana GN=NMT3 PE=2 SV=2
Length = 490
Score = 73 bits (177), Expect = 5e-012
Identities = 47/153 (30%), Positives = 75/153 (49%), Gaps = 6/153 (3%)
Frame = +1
Query: 457 VDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALC 636
VD++ +KPGQK+LDVGCG+GG +A + +VVGI ++ + A +H GL
Sbjct: 274 VDMLDLKPGQKVLDVGCGIGGGDFYMAENFDVDVVGIDLSVNMISFALEH--AIGLKCSV 331
Query: 637 EVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKF 816
E + + + DNTFD YS + H ++ Y+ LKPG + ++ + K
Sbjct: 332 EFEVADCTKKEYPDNTFDVIYSRDTILHIQDKPALFRRFYKWLKPGGKVLITDYCRSPKT 391
Query: 817 NAEDEEHVEVIQGIERGDALPGLRAYSDIAEAA 915
+ D I +RG L ++AY + A
Sbjct: 392 PSPD----FAIYIKKRGYDLHDVQAYGQMLRDA 420
>sp|Q9ZSK1|GTOMC_ARATH Tocopherol O-methyltransferase, chloroplastic
OS=Arabidopsis thaliana GN=G-TMT PE=2 SV=2
Length = 348
Score = 72 bits (176), Expect = 6e-012
Identities = 45/140 (32%), Positives = 66/140 (47%), Gaps = 6/140 (4%)
Frame = +1
Query: 397 SPSIRGKSHRDA-TRLHEEM-----AVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANV 558
S + H++A R+ EE D + K +K++DVGCG+GG R +AS A
Sbjct: 93 SVQLSDSGHKEAQIRMIEESLRFAGVTDEEEEKKIKKVVDVGCGIGGSSRYLASKFGAEC 152
Query: 559 VGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEE 738
+GIT++ Q KRA D L + L PF+D FD +S+E+ H P +
Sbjct: 153 IGITLSPVQAKRANDLAAAQSLAHKASFQVADALDQPFEDGKFDLVWSMESGEHMPDKAK 212
Query: 739 VYAEIYRVLKPGSLYVSYEW 798
E+ RV PG + W
Sbjct: 213 FVKELVRVAAPGGRIIIVTW 232
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,414,502,248
Number of Sequences: 518415
Number of Extensions: 42414502248
Number of Successful Extensions: 312188416
Number of sequences better than 0.0: 0
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