BLASTX 7.6.2
Query= UN10607 /QuerySize=1735
(1734 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54Z26|GLYC1_DICDI Serine hydroxymethyltransferase 1 OS=Dicty... 587 1e-166
sp|Q54EW1|GLYC2_DICDI Serine hydroxymethyltransferase 2 OS=Dicty... 576 2e-163
sp|P34899|GLYM_PEA Serine hydroxymethyltransferase, mitochondria... 552 5e-156
sp|Q9SZJ5|GLYM_ARATH Serine hydroxymethyltransferase, mitochondr... 547 9e-155
sp|P49357|GLYM_FLAPR Serine hydroxymethyltransferase 1, mitochon... 542 4e-153
sp|P49358|GLYN_FLAPR Serine hydroxymethyltransferase 2, mitochon... 538 4e-152
sp|P50433|GLYM_SOLTU Serine hydroxymethyltransferase, mitochondr... 538 7e-152
sp|P34896|GLYC_HUMAN Serine hydroxymethyltransferase, cytosolic ... 532 5e-150
sp|Q5RFK5|GLYC_PONAB Serine hydroxymethyltransferase, cytosolic ... 531 7e-150
sp|Q3SZ20|GLYM_BOVIN Serine hydroxymethyltransferase, mitochondr... 531 9e-150
sp|P14519|GLYM_RABIT Serine hydroxymethyltransferase, mitochondr... 527 1e-148
sp|P34897|GLYM_HUMAN Serine hydroxymethyltransferase, mitochondr... 526 2e-148
sp|P07511|GLYC_RABIT Serine hydroxymethyltransferase, cytosolic ... 526 3e-148
sp|P50431|GLYC_MOUSE Serine hydroxymethyltransferase, cytosolic ... 525 5e-148
sp|P34898|GLYC_NEUCR Serine hydroxymethyltransferase, cytosolic ... 484 1e-135
sp|O13426|GLYC_CANAL Serine hydroxymethyltransferase, cytosolic ... 469 4e-131
sp|P37291|GLYC_YEAST Serine hydroxymethyltransferase, cytosolic ... 469 4e-131
sp|Q6FUP6|GLYC_CANGA Serine hydroxymethyltransferase, cytosolic ... 468 7e-131
sp|Q6CLQ5|GLYM_KLULA Serine hydroxymethyltransferase, mitochondr... 465 5e-130
sp|Q758F0|GLYM_ASHGO Serine hydroxymethyltransferase, mitochondr... 463 2e-129
>sp|Q54Z26|GLYC1_DICDI Serine hydroxymethyltransferase 1 OS=Dictyostelium
discoideum GN=shmt1 PE=1 SV=1
Length = 457
Score = 587 bits (1511), Expect = 1e-166
Identities = 289/457 (63%), Positives = 361/457 (78%), Gaps = 3/457 (0%)
Frame = -3
Query: 1696 SAWGNTPLVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMP 1517
S GNTPL VD EI +L+ +EK RQ +G+ELIASENFTS AV+EALGS TNKY+EG P
Sbjct: 3 SVSGNTPLKEVDNEIFELMNREKDRQFKGLELIASENFTSRAVMEALGSHFTNKYAEGYP 62
Query: 1516 GNRYYGGNEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRI 1337
G+RYYGG E +D +E LC+ RAL+AFRLD + WGVNVQPYSGSPANFA YTALL+PHDRI
Sbjct: 63 GSRYYGGTEVVDELETLCQKRALKAFRLDESKWGVNVQPYSGSPANFAVYTALLRPHDRI 122
Query: 1336 MGLDLPSGGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKL 1157
MGLDLPSGGHLTHGY T KKISA+SI+FES+PY++ G IDY +LEE A+ F+PKL
Sbjct: 123 MGLDLPSGGHLTHGYQTD-KKKISASSIFFESMPYQIG-ADGLIDYQRLEENALLFKPKL 180
Query: 1156 LICGGSAYPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHK 977
+I G SAYPR+WDY R+RA+ADKVGA L+CDMAH SGLVAAQ +PF+YCDVVT+TTHK
Sbjct: 181 IISGASAYPREWDYKRMRAIADKVGAYLMCDMAHYSGLVAAQLLDSPFDYCDVVTSTTHK 240
Query: 976 SLRGPRAGMIFYRKGPKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALK 797
+LRGPR+G+IF+R+G + G+ E YD E KINFAVFP+LQGGPH + I +AVALK
Sbjct: 241 TLRGPRSGIIFFRRGKRVDGNGK-EIEEYDIESKINFAVFPSLQGGPHENVIAGVAVALK 299
Query: 796 QANTPGFKVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLC 617
+A++ FK YA QVK NA A+ N LM KGY +VT GT+NHL+LWDLRP LTGNK EK
Sbjct: 300 EADSQEFKEYALQVKKNAAAIGNALMNKGYKLVTNGTDNHLILWDLRPKELTGNKFEKAA 359
Query: 616 DLCDITLNKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQK 437
D+ +IT+NKNAV GD++A++PGG+RIG+ A+TSRGL E DFE I +FL R V+++L IQ
Sbjct: 360 DIANITVNKNAVHGDTNAISPGGIRIGSSALTSRGLKEADFEKIADFLDRIVSISLEIQG 419
Query: 436 EHGKLLKDFNKGLVNNKEIEELKADVEKFAASYEMPG 326
GK L DF + +KE+ +L+ +VE+F++ + +PG
Sbjct: 420 RVGKKLVDFVVEINKSKELLDLRKEVEEFSSKFTLPG 456
>sp|Q54EW1|GLYC2_DICDI Serine hydroxymethyltransferase 2 OS=Dictyostelium
discoideum GN=shmt2 PE=3 SV=1
Length = 481
Score = 576 bits (1484), Expect = 2e-163
Identities = 277/450 (61%), Positives = 359/450 (79%), Gaps = 8/450 (1%)
Frame = -3
Query: 1663 DPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNRYYGGNEFI 1484
DPEI+DL+ KEK+RQ G+ELIASENFTS AV+E++GS TNKY+EG+PG RYYGGNE +
Sbjct: 38 DPEIYDLMMKEKQRQFTGLELIASENFTSRAVMESIGSCFTNKYAEGLPGARYYGGNEVV 97
Query: 1483 DLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHL 1304
D +ENLC RALE F L+ WGVNVQPYSGS ANFAA+T LL+PHDRIMGLDLPSGGHL
Sbjct: 98 DQLENLCIKRALETFNLNPEEWGVNVQPYSGSTANFAAFTGLLKPHDRIMGLDLPSGGHL 157
Query: 1303 THGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLICGGSAYPRD 1124
THGY T KKISATSI+FES+PY+VN TGY+DY+K+E A FRPKLLI G SAYPR+
Sbjct: 158 THGYQTD-KKKISATSIFFESMPYQVN-ETGYVDYNKMEANAALFRPKLLIAGASAYPRE 215
Query: 1123 WDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPRAGMIF 944
WDY R+R +ADK GA LLCDMAHISG+VA ++A +PF +CDVVTTTTHK+LRGPRAG+IF
Sbjct: 216 WDYERMRKIADKHGAYLLCDMAHISGMVAGKQAISPFLFCDVVTTTTHKTLRGPRAGLIF 275
Query: 943 YRKGPKPPKKGQAEGAVY--DFEDKINFAVFPALQGGPHNHQIGALAVALKQANTPGFKV 770
+RK K+ A+G + D E++INFAVFP+ QGGPH + I +AVALK+A++P F+
Sbjct: 276 FRK----TKRRDAKGNIIDDDLENRINFAVFPSCQGGPHENTIAGIAVALKEASSPDFQE 331
Query: 769 YAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCDITLNK 590
Y KQV+ N+ + L +GYS+VT GT+NHLVLWDLRP G+TG+K+EK CD IT+NK
Sbjct: 332 YTKQVRRNSQTMGEELKKRGYSLVTEGTDNHLVLWDLRPQGITGSKIEKACDEAHITVNK 391
Query: 589 NAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKEHGKLLKDF 410
NAV+GD++A+APGGVR+G PA+TSRGL E+DF + +FL R V ++L+IQ + GK + DF
Sbjct: 392 NAVYGDTNAIAPGGVRLGAPALTSRGLKEQDFVKVVDFLDRVVKISLDIQSKVGKKMPDF 451
Query: 409 NKGLVNNKEIEELKADVEKFAASYEMPGFL 320
+ + +N+++++++ +V++F+ + MPG L
Sbjct: 452 QRAIADNQDLKQIRQEVKEFSTKFGMPGEL 481
>sp|P34899|GLYM_PEA Serine hydroxymethyltransferase, mitochondrial OS=Pisum
sativum PE=1 SV=1
Length = 518
Score = 552 bits (1420), Expect = 5e-156
Identities = 281/466 (60%), Positives = 347/466 (74%), Gaps = 7/466 (1%)
Frame = -3
Query: 1684 NTPLVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNRY 1505
N+PL +DPEI D+IE EK RQ +G+ELI SENFTS +V++A+GS +TNKYSEG PG RY
Sbjct: 53 NSPLEVIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 112
Query: 1504 YGGNEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGLD 1325
YGGNE+ID+ E LC+ RALEAFRLD A WGVNVQP SGSP+NF YTALL+PHDRIM LD
Sbjct: 113 YGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFQVYTALLKPHDRIMALD 172
Query: 1324 LPSGGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLICG 1145
LP GGHL+HGY T KKISA SI+FE++PY+++ +TGYIDYD+LE+ A FRPKL++ G
Sbjct: 173 LPHGGHLSHGYQTD-TKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAG 231
Query: 1144 GSAYPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRG 965
SAY R +DYAR+R V DK A+LL DMAHISGLVAA +PF+Y DVVTTTTHKSLRG
Sbjct: 232 ASAYARLYDYARIRKVCDKQKAVLLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRG 291
Query: 964 PRAGMIFYRKGPKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANT 785
PR MIF+RKG K K Q + YD+EDKIN AVFP LQGGPHNH I LAVALKQA T
Sbjct: 292 PRGAMIFFRKGLKEVNK-QGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATT 350
Query: 784 PGFKVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCD 605
P ++ Y +QV +N+ A L KGY +V+GGTENHLVL +L+ G+ G++VEK+ +L
Sbjct: 351 PEYRAYQEQVLSNSSKFAKALSEKGYDLVSGGTENHLVLVNLKNKGIDGSRVEKVLELVH 410
Query: 604 ITLNKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKE-HG 428
I NKN V GD SA+ PGG+R+GTPA+TSRG VE+DF + E+ +V+L L ++ E G
Sbjct: 411 IAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDAAVSLALKVKAESKG 470
Query: 427 KLLKDFNKGLVNN----KEIEELKADVEKFAASYEMPGFLMSEMKY 302
LKDF + L + EI +LK DVE+FA + GF + MKY
Sbjct: 471 TKLKDFVEALQTSSYVQSEISKLKHDVEEFAKQFPTIGFEKATMKY 516
>sp|Q9SZJ5|GLYM_ARATH Serine hydroxymethyltransferase, mitochondrial
OS=Arabidopsis thaliana GN=SHM1 PE=1 SV=1
Length = 517
Score = 547 bits (1409), Expect = 9e-155
Identities = 275/468 (58%), Positives = 348/468 (74%), Gaps = 7/468 (1%)
Frame = -3
Query: 1684 NTPLVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNRY 1505
N PL VDPEI D+IE EK RQ +G+ELI SENFTS +V++A+GS +TNKYSEG PG RY
Sbjct: 52 NAPLEEVDPEIADIIEHEKARQWKGLELIPSENFTSVSVMQAVGSVMTNKYSEGYPGARY 111
Query: 1504 YGGNEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGLD 1325
YGGNE+ID+ E LC+ RALEAFRLD WGVNVQP SGSPANF YTALL+PH+RIM LD
Sbjct: 112 YGGNEYIDMAETLCQKRALEAFRLDPEKWGVNVQPLSGSPANFHVYTALLKPHERIMALD 171
Query: 1324 LPSGGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLICG 1145
LP GGHL+HGY T KKISA SI+FE++PY+++ +TGYIDYD++E+ A FRPKL++ G
Sbjct: 172 LPHGGHLSHGYQTD-TKKISAVSIFFETMPYRLDESTGYIDYDQMEKSATLFRPKLIVAG 230
Query: 1144 GSAYPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRG 965
SAY R +DYAR+R V +K A++L DMAHISGLVAA +PF+Y DVVTTTTHKSLRG
Sbjct: 231 ASAYARLYDYARIRKVCNKQKAVMLADMAHISGLVAANVIPSPFDYADVVTTTTHKSLRG 290
Query: 964 PRAGMIFYRKGPKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANT 785
PR MIF+RKG K K Q + +YDFEDKIN AVFP LQGGPHNH I LAVALKQA T
Sbjct: 291 PRGAMIFFRKGVKEINK-QGKEVLYDFEDKINQAVFPGLQGGPHNHTITGLAVALKQATT 349
Query: 784 PGFKVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCD 605
+K Y +QV +N+ A LM +GY +V+GGT+NHLVL +L+P G+ G++VEK+ +
Sbjct: 350 SEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVH 409
Query: 604 ITLNKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKE-HG 428
I NKN V GD SA+ PGG+R+GTPA+TSRG VE+DF + E+ ++VT+ L ++ E G
Sbjct: 410 IASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQG 469
Query: 427 KLLKDFNKGLVNN----KEIEELKADVEKFAASYEMPGFLMSEMKYQH 296
LKDF + ++ EI +L+ +VE+FA + GF MKY++
Sbjct: 470 TKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 517
>sp|P49357|GLYM_FLAPR Serine hydroxymethyltransferase 1, mitochondrial
OS=Flaveria pringlei PE=2 SV=1
Length = 517
Score = 542 bits (1395), Expect = 4e-153
Identities = 278/467 (59%), Positives = 342/467 (73%), Gaps = 6/467 (1%)
Frame = -3
Query: 1684 NTPLVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNRY 1505
N PL VDPEI D+IE EK RQ +G+ELI SENFTS +V++A+GS +TNKYSEG PG RY
Sbjct: 53 NAPLEVVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 112
Query: 1504 YGGNEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGLD 1325
YGGNE+ID+ E LC+ RALEAFRLD A WGVNVQP SGSPANF YTALL+ HDRIM LD
Sbjct: 113 YGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPANFHVYTALLKAHDRIMALD 172
Query: 1324 LPSGGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLICG 1145
LP GGHL+HGY T KKISA SI+FE++PY++N +TGYIDYD+LE+ A FRPKL++ G
Sbjct: 173 LPHGGHLSHGYQTD-TKKISAVSIFFETMPYRLNESTGYIDYDQLEKSATLFRPKLIVAG 231
Query: 1144 GSAYPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRG 965
SAY R +DYAR+R V DK A++L DMAHISGLVAA +PF+Y DVVTTTTHKSLRG
Sbjct: 232 ASAYARLYDYARIRKVCDKQKAIMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRG 291
Query: 964 PRAGMIFYRKGPKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANT 785
PR MIF+RKG K K Q + YD+EDKIN AVFP LQGGPHNH I LAVALKQA T
Sbjct: 292 PRGAMIFFRKGLKEVNK-QGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATT 350
Query: 784 PGFKVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCD 605
+K Y +QV +N+ A L+ GY +V+GGTENHLVL +L+ G+ G+KVEK+ +
Sbjct: 351 AEYKAYQEQVMSNSAKFAETLVKSGYELVSGGTENHLVLVNLKNKGIDGSKVEKVLEAVH 410
Query: 604 ITLNKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKE-HG 428
I NKN V GD SA+ PGG+R+GTPA+TSRG VE+DF + F +V L + I+ E G
Sbjct: 411 IAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAYFFDLAVKLAVKIKGEAKG 470
Query: 427 KLLKDFNKGLVNN---KEIEELKADVEKFAASYEMPGFLMSEMKYQH 296
LKDF + ++ EI +L+ DVE++A + GF MKY++
Sbjct: 471 TKLKDFVTAMESSAIQSEISKLRHDVEEYAKQFPTIGFEKETMKYKN 517
>sp|P49358|GLYN_FLAPR Serine hydroxymethyltransferase 2, mitochondrial
OS=Flaveria pringlei PE=2 SV=1
Length = 517
Score = 538 bits (1386), Expect = 4e-152
Identities = 276/467 (59%), Positives = 341/467 (73%), Gaps = 6/467 (1%)
Frame = -3
Query: 1684 NTPLVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNRY 1505
N PL DPEI D+IE EK RQ +G+ELI SENFTS +V++A+GS +TNKYSEG PG RY
Sbjct: 53 NAPLEVGDPEIADIIELEKARQWKGLELILSENFTSLSVMQAVGSVMTNKYSEGYPGARY 112
Query: 1504 YGGNEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGLD 1325
YGGNE+ID+ E LC+ RALEAFRLD+A WGVNVQP SGSPANF YTALL+ HDRIM LD
Sbjct: 113 YGGNEYIDMAETLCQKRALEAFRLDAAKWGVNVQPLSGSPANFHVYTALLKAHDRIMALD 172
Query: 1324 LPSGGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLICG 1145
LP GGHL+HGY T KKISA SI+FE++PY++N +TGYIDYD+LE+ A FRPKL++ G
Sbjct: 173 LPHGGHLSHGYQTD-TKKISAVSIFFETMPYRLNESTGYIDYDQLEKSATLFRPKLIVAG 231
Query: 1144 GSAYPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRG 965
SAY R +DYAR+R V DK A+LL DMAHISGLVAA +PF+Y DVVTTTTHKSLRG
Sbjct: 232 ASAYARLYDYARIRKVCDKQKAILLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRG 291
Query: 964 PRAGMIFYRKGPKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANT 785
PR MIF+RKG K K Q + +YD+EDKIN AVFP LQGGPHNH I LAVALKQA T
Sbjct: 292 PRGAMIFFRKGVKEVNK-QGKEVLYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATT 350
Query: 784 PGFKVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCD 605
+K Y +QV +N A L+ GY +V+GGTENHLVL +L+ G+ G++VEK+ +
Sbjct: 351 AEYKAYQEQVMSNCAKFAETLVKSGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVH 410
Query: 604 ITLNKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKE-HG 428
I NKN V GD SA+ PGG+R+GTPA+TSRG VE+DF + +V L + I+ E G
Sbjct: 411 IAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAYLFDLAVKLAVKIKGEAQG 470
Query: 427 KLLKDFNKGLVNN---KEIEELKADVEKFAASYEMPGFLMSEMKYQH 296
LKDF + ++ EI +L+ DVE++A + GF MKY++
Sbjct: 471 TKLKDFVAAMQSSAFQSEISKLRHDVEEYAKQFPTIGFEKETMKYKN 517
>sp|P50433|GLYM_SOLTU Serine hydroxymethyltransferase, mitochondrial OS=Solanum
tuberosum PE=2 SV=1
Length = 518
Score = 538 bits (1384), Expect = 7e-152
Identities = 273/468 (58%), Positives = 344/468 (73%), Gaps = 7/468 (1%)
Frame = -3
Query: 1684 NTPLVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNRY 1505
N PL VDPEI D+IE EK RQ +G+ELI SENFTS +V++A+GS +TNKYSEG PG RY
Sbjct: 53 NAPLEVVDPEIADIIEHEKARQWKGLELIPSENFTSVSVMQAVGSVMTNKYSEGYPGARY 112
Query: 1504 YGGNEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGLD 1325
YGGNE+ID+ E LC+ RALEAFRLD A WGVNVQP SGSPANF YTALL+PH+RIM LD
Sbjct: 113 YGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPANFQVYTALLKPHERIMALD 172
Query: 1324 LPSGGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLICG 1145
LP GGHL+HGY T KKISA SI+FE++PY+++ +TGYIDYD+LE+ A FRPKL++ G
Sbjct: 173 LPHGGHLSHGYQTD-TKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAG 231
Query: 1144 GSAYPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRG 965
SAY R +DY R+R V +K A+LL DMAHISGLVAA +PF+Y DVVTTTTHKSLRG
Sbjct: 232 ASAYARLYDYDRIRKVCNKQKAILLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRG 291
Query: 964 PRAGMIFYRKGPKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANT 785
PR MIFYRKG K K Q + YD+EDKIN AVFP LQGGPHNH I LAVALKQA T
Sbjct: 292 PRGAMIFYRKGVKEVNK-QGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATT 350
Query: 784 PGFKVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCD 605
P ++ Y +QV +N+ A L KGY +V+GGT+NHLVL +++ G+ G++VEK+ +
Sbjct: 351 PEYRAYQEQVLSNSSKFAQALGEKGYELVSGGTDNHLVLVNMKNKGIDGSRVEKVLEAVH 410
Query: 604 ITLNKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKE-HG 428
I NKN V GD SA+ PGG+R+GTPA+TSRG +E+DF + +F +V + + ++ E G
Sbjct: 411 IAANKNTVPGDVSAMVPGGIRMGTPALTSRGFLEEDFVKVADFFDAAVKIAVKVKAETQG 470
Query: 427 KLLKDFNKGLVNN----KEIEELKADVEKFAASYEMPGFLMSEMKYQH 296
LKDF L ++ EI +L+ DVE++A + GF MKY++
Sbjct: 471 TKLKDFVATLESSAPIKSEIAKLRHDVEEYAKQFPTIGFEKETMKYKN 518
>sp|P34896|GLYC_HUMAN Serine hydroxymethyltransferase, cytosolic OS=Homo sapiens
GN=SHMT1 PE=1 SV=1
Length = 483
Score = 532 bits (1368), Expect = 5e-150
Identities = 273/456 (59%), Positives = 331/456 (72%), Gaps = 6/456 (1%)
Frame = -3
Query: 1678 PLVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNRYYG 1499
PL D E++++I+KE RQ G+ELIASENF S AV+EALGS L NKYSEG PG RYYG
Sbjct: 25 PLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84
Query: 1498 GNEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLP 1319
G EFID +E LC+ RAL+A++LD WGVNVQPYSGSPANFA YTAL++PH RIMGLDLP
Sbjct: 85 GTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLP 144
Query: 1318 SGGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLICGGS 1139
GGHLTHG+ T KKISATSI+FES+PYKVN TGYI+YD+LEE A F PKL+I G S
Sbjct: 145 DGGHLTHGFMTD-KKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTS 203
Query: 1138 AYPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPR 959
Y R+ +YARLR +AD+ GA L+ DMAHISGLVAA +PFE+C VVTTTTHK+LRG R
Sbjct: 204 CYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCR 263
Query: 958 AGMIFYRKGPKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANTPG 779
AGMIFYRKG K + +Y+ E IN AVFP LQGGPHNH I +AVALKQA T
Sbjct: 264 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 323
Query: 778 FKVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCDIT 599
FKVY QV AN AL+ L GY IVTGG++NHL+L DLR G G + EK+ + C I
Sbjct: 324 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383
Query: 598 LNKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKEHG--K 425
NKN GD SAL P G+R+GTPA+TSRGL+EKDF+ + F+ R + LTL IQ + G
Sbjct: 384 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRA 443
Query: 424 LLKDFNKGLVNNK---EIEELKADVEKFAASYEMPG 326
LK+F + L +K ++ L+ +VE FA+ + +PG
Sbjct: 444 TLKEFKERLAGDKYQAAVQALREEVESFASLFPLPG 479
>sp|Q5RFK5|GLYC_PONAB Serine hydroxymethyltransferase, cytosolic OS=Pongo abelii
GN=SHMT1 PE=2 SV=1
Length = 483
Score = 531 bits (1367), Expect = 7e-150
Identities = 273/456 (59%), Positives = 330/456 (72%), Gaps = 6/456 (1%)
Frame = -3
Query: 1678 PLVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNRYYG 1499
PL D E++++I+KE RQ G+EL ASENF S AV+EALGS L NKYSEG PG RYYG
Sbjct: 25 PLKDSDVEVYNIIKKESNRQRVGLELFASENFASQAVLEALGSCLNNKYSEGYPGQRYYG 84
Query: 1498 GNEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLP 1319
G EFID +E LC+ RAL+A++LD WGVNVQPYSGSPANFA YTAL++PH RIMGLDLP
Sbjct: 85 GTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLP 144
Query: 1318 SGGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLICGGS 1139
GGHLTHG+ T G KKISATSI+FES+PYKVN TGYI+YD+LEE A F PKL+I G S
Sbjct: 145 DGGHLTHGFMT-GKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTS 203
Query: 1138 AYPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPR 959
Y R+ DYARLR +AD+ GA L+ DMAHISGLVAA +PFE+C VVTTTTHK+LRG R
Sbjct: 204 CYSRNLDYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCR 263
Query: 958 AGMIFYRKGPKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANTPG 779
AGMIFYRKG + + +Y+ E IN AVFP LQGGPHNH I +AVALKQA T
Sbjct: 264 AGMIFYRKGVQSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 323
Query: 778 FKVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCDIT 599
FKVY QV AN AL+ L GY IVTGG++NHL+L DLR G G + EK+ + C I
Sbjct: 324 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383
Query: 598 LNKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKEHG--K 425
NKN GD SAL P G+R+GTPA+TSRGL+EKDF+ + F+ R + LTL IQ + G
Sbjct: 384 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRA 443
Query: 424 LLKDFNKGLVNNK---EIEELKADVEKFAASYEMPG 326
LK+F + L +K ++ L+ VE FA+ + +PG
Sbjct: 444 TLKEFKERLAGDKYQGAVQALREKVESFASLFPLPG 479
>sp|Q3SZ20|GLYM_BOVIN Serine hydroxymethyltransferase, mitochondrial OS=Bos
taurus GN=SHMT2 PE=2 SV=1
Length = 504
Score = 531 bits (1366), Expect = 9e-150
Identities = 274/459 (59%), Positives = 337/459 (73%), Gaps = 6/459 (1%)
Frame = -3
Query: 1687 GNTPLVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNR 1508
G L DPE+ +L+ +EK RQCRG+ELIASENF S A +EALGS L NKYSEG PG R
Sbjct: 45 GQESLSDSDPEMWELLRREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKR 104
Query: 1507 YYGGNEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGL 1328
YYGG E +D IE LC+ RALEAF LD A WGVNVQPYSGSPAN AAYTALLQPHDRIMGL
Sbjct: 105 YYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGL 164
Query: 1327 DLPSGGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLIC 1148
DLP GGHLTHG Y S K+ISATSI+FES+PYK+N TG IDYD+L A F+P+L+I
Sbjct: 165 DLPDGGHLTHG-YMSDVKRISATSIFFESMPYKLNPQTGLIDYDQLALTARLFKPRLIIA 223
Query: 1147 GGSAYPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLR 968
G SAY R DYAR+R V D+V A LL DMAHISGLVAA+ +PF++ D+VTTTTHK+LR
Sbjct: 224 GTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLR 283
Query: 967 GPRAGMIFYRKGPKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQAN 788
G R+G+IFYRKG + Y FED+INFAVFP+LQGGPHNH I A+AVALKQA
Sbjct: 284 GARSGLIFYRKGVQAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQAC 343
Query: 787 TPGFKVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLC 608
TP F+ Y+ Q+ NA A+AN L+ +GYS+V+GGT+NHLVL DLRP GL G + E++ +L
Sbjct: 344 TPMFREYSLQILKNAQAMANALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 403
Query: 607 DITLNKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKEHG 428
IT NKN GD SA+ PGG+R+G PA+TSRG +E DF + F+ V + L ++ +
Sbjct: 404 SITANKNTCPGDRSAITPGGLRLGAPALTSRGFLEDDFRKVVGFIDEGVNIGLEVKSKTT 463
Query: 427 KLLKDFNKGLVNNKE----IEELKADVEKFAASYEMPGF 323
K L+DF L+ + E + +L+ VE+FA ++ MPGF
Sbjct: 464 K-LQDFKSFLLKDPETSHQLADLRQRVEQFARAFPMPGF 501
>sp|P14519|GLYM_RABIT Serine hydroxymethyltransferase, mitochondrial
OS=Oryctolagus cuniculus GN=SHMT2 PE=1 SV=2
Length = 504
Score = 527 bits (1356), Expect = 1e-148
Identities = 275/461 (59%), Positives = 341/461 (73%), Gaps = 10/461 (2%)
Frame = -3
Query: 1687 GNTPLVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNR 1508
G L DPE+ +L+++EK RQCRG+ELIASENF A +EALGS L NKYSEG PG R
Sbjct: 45 GQESLSDTDPEMWELLQREKDRQCRGLELIASENFCIRAALEALGSCLNNKYSEGYPGKR 104
Query: 1507 YYGGNEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGL 1328
YYGG E +D IE LC+ RALEAF LD A WGVNVQPYSGSPAN AAYTALLQPHDRIMGL
Sbjct: 105 YYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGL 164
Query: 1327 DLPSGGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLIC 1148
DLP GGHLTHG Y S K++SATSI+FES+PYK+N TG IDY++L A FRP+L+I
Sbjct: 165 DLPDGGHLTHG-YMSDVKRVSATSIFFESMPYKLNPQTGLIDYEQLALTARLFRPRLIIA 223
Query: 1147 GGSAYPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLR 968
G SAY R DYAR+R V D+V A LL DMAHISGLVAA+ +PF++ DVVTTTTHK+LR
Sbjct: 224 GTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLR 283
Query: 967 GPRAGMIFYRKGPK--PPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQ 794
G R+G+IFYRKG + PK GQ Y FED+INFAVFP+LQGGPHNH I A+AVALKQ
Sbjct: 284 GARSGLIFYRKGVRTVDPKTGQE--IPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQ 341
Query: 793 ANTPGFKVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCD 614
A TP F+ Y+ QV NA A+A+ L+ +GYS+V+GGT+NHLVL DLRP GL G + E++ +
Sbjct: 342 ACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLE 401
Query: 613 LCDITLNKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKE 434
L IT NKN GD SA+ PGG+R+G PA+TSR E DF + +F+ V + L ++++
Sbjct: 402 LVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKRK 461
Query: 433 HGKLLKDFNKGLVNNKE----IEELKADVEKFAASYEMPGF 323
K L+DF L+ + E + +L+ V++FA ++ MPGF
Sbjct: 462 TAK-LQDFKSFLLKDPETSQHLADLRRRVQQFARAFPMPGF 501
>sp|P34897|GLYM_HUMAN Serine hydroxymethyltransferase, mitochondrial OS=Homo
sapiens GN=SHMT2 PE=1 SV=3
Length = 504
Score = 526 bits (1354), Expect = 2e-148
Identities = 273/459 (59%), Positives = 335/459 (72%), Gaps = 6/459 (1%)
Frame = -3
Query: 1687 GNTPLVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNR 1508
G L DPE+ +L+++EK RQCRG+ELIASENF S A +EALGS L NKYSEG PG R
Sbjct: 45 GQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKR 104
Query: 1507 YYGGNEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGL 1328
YYGG E +D IE LC+ RALEAF LD A WGVNVQPYSGSPAN A YTALLQPHDRIMGL
Sbjct: 105 YYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGL 164
Query: 1327 DLPSGGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLIC 1148
DLP GGHLTHG Y S K+ISATSI+FES+PYK+N TG IDY++L A FRP+L+I
Sbjct: 165 DLPDGGHLTHG-YMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIA 223
Query: 1147 GGSAYPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLR 968
G SAY R DYAR+R V D+V A LL DMAHISGLVAA+ +PF++ D+VTTTTHK+LR
Sbjct: 224 GTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLR 283
Query: 967 GPRAGMIFYRKGPKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQAN 788
G R+G+IFYRKG K Y FED+INFAVFP+LQGGPHNH I A+AVALKQA
Sbjct: 284 GARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQAC 343
Query: 787 TPGFKVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLC 608
TP F+ Y+ QV NA A+A+ L+ +GYS+V+GGT+NHLVL DLRP GL G + E++ +L
Sbjct: 344 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 403
Query: 607 DITLNKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKEHG 428
IT NKN GD SA+ PGG+R+G PA+TSR E DF + +F+ V + L ++ +
Sbjct: 404 SITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTA 463
Query: 427 KLLKDFNKGLVNNKE----IEELKADVEKFAASYEMPGF 323
K L+DF L+ + E + L+ VE+FA ++ MPGF
Sbjct: 464 K-LQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGF 501
>sp|P07511|GLYC_RABIT Serine hydroxymethyltransferase, cytosolic OS=Oryctolagus
cuniculus GN=SHMT1 PE=1 SV=2
Length = 484
Score = 526 bits (1353), Expect = 3e-148
Identities = 269/457 (58%), Positives = 328/457 (71%), Gaps = 7/457 (1%)
Frame = -3
Query: 1678 PLVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNRYYG 1499
PL D E++D+I+KE RQ G+ELIASENF S AV+EALGS L NKYSEG PG RYYG
Sbjct: 25 PLKDSDAEVYDIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84
Query: 1498 GNEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLP 1319
G E ID +E LC+ RAL+A+ LD WGVNVQPYSGSPANFA YTAL++PH RIMGLDLP
Sbjct: 85 GTEHIDELETLCQKRALQAYGLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLP 144
Query: 1318 SGGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLICGGS 1139
GGHLTHG+ T KKISATSI+FES+ YKVN TGYIDYD+LEE A F PKL+I G S
Sbjct: 145 DGGHLTHGFMTD-KKKISATSIFFESMAYKVNPDTGYIDYDRLEENARLFHPKLIIAGTS 203
Query: 1138 AYPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPR 959
Y R+ DY RLR +AD+ GA L+ DMAHISGLV A +PFE+C VVTTTTHK+LRG R
Sbjct: 204 CYSRNLDYGRLRKIADENGAYLMADMAHISGLVVAGVVPSPFEHCHVVTTTTHKTLRGCR 263
Query: 958 AGMIFYRKGPKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANTPG 779
AGMIFYR+G + + +Y+ E IN AVFP LQGGPHNH I +AVALKQA TP
Sbjct: 264 AGMIFYRRGVRSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTPE 323
Query: 778 FKVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCDIT 599
FK Y +QV AN AL+ L+ GY IVTGG++NHL+L DLR G G + EK+ + C I
Sbjct: 324 FKEYQRQVVANCRALSAALVELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383
Query: 598 LNKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKEHG--K 425
NKN GD SAL P G+R+GTPA+TSRGL+EKDF+ + F+ R + LT+ IQ + G
Sbjct: 384 CNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTVQIQDDTGPRA 443
Query: 424 LLKDFNKGLVNNKE----IEELKADVEKFAASYEMPG 326
LK+F + L +++ + L+ +VE FAA + +PG
Sbjct: 444 TLKEFKEKLAGDEKHQRAVRALRQEVESFAALFPLPG 480
>sp|P50431|GLYC_MOUSE Serine hydroxymethyltransferase, cytosolic OS=Mus musculus
GN=Shmt1 PE=1 SV=2
Length = 478
Score = 525 bits (1351), Expect = 5e-148
Identities = 269/457 (58%), Positives = 328/457 (71%), Gaps = 7/457 (1%)
Frame = -3
Query: 1678 PLVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNRYYG 1499
PL D E++ +I+KE RQ G+ELIASENF S AV+EALGS+L NKYSEG PG RYYG
Sbjct: 19 PLKDSDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALGSSLNNKYSEGYPGQRYYG 78
Query: 1498 GNEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLP 1319
G EFID +E LC+ RAL+A+ LD WGVNVQPYSGSPANFA YTAL++PH RIMGLDLP
Sbjct: 79 GTEFIDELEMLCQKRALQAYHLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLP 138
Query: 1318 SGGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLICGGS 1139
GGHLTHG+ T KKISATSI+FES+PYKV TGYI+YD+LEE A F PKL+I G S
Sbjct: 139 DGGHLTHGFMTD-KKKISATSIFFESMPYKVYPETGYINYDQLEENASLFHPKLIIAGTS 197
Query: 1138 AYPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPR 959
Y R+ DYARLR +AD GA L+ DMAHISGLVAA +PFE+C VVTTTTHK+LRG R
Sbjct: 198 CYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCR 257
Query: 958 AGMIFYRKGPKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANTPG 779
AGMIFYRKG + + Y+ E IN AVFP LQGGPHNH I +AVALKQA T
Sbjct: 258 AGMIFYRKGVRSVDPKTGKETYYELESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTTE 317
Query: 778 FKVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCDIT 599
FK+Y QV AN AL++ L GY IVTGG++NHL+L DLR G G + EK+ + C I
Sbjct: 318 FKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRSKGTDGGRAEKVLEACSIA 377
Query: 598 LNKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKEHG--K 425
NKN GD SAL P G+R+GTPA+TSRGL+E+DF+ + F+ R + LTL IQ
Sbjct: 378 CNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHRGIELTLQIQSHMATKA 437
Query: 424 LLKDFNKGLVNNKEIEE----LKADVEKFAASYEMPG 326
LK+F + L +++I+ L+ +VE FA+++ +PG
Sbjct: 438 TLKEFKEKLAGDEKIQSAVATLREEVENFASNFSLPG 474
>sp|P34898|GLYC_NEUCR Serine hydroxymethyltransferase, cytosolic OS=Neurospora
crassa GN=for PE=3 SV=2
Length = 480
Score = 484 bits (1245), Expect = 1e-135
Identities = 256/455 (56%), Positives = 320/455 (70%), Gaps = 8/455 (1%)
Frame = -3
Query: 1675 LVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNRYYGG 1496
LV DP++ ++++KE +RQ I LIASEN TS AV +ALGS ++NKYSEG+PG RYYGG
Sbjct: 18 LVESDPQVAEIMKKEVQRQRESIILIASENVTSRAVFDALGSPMSNKYSEGLPGARYYGG 77
Query: 1495 NEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPS 1316
N+ ID IE LC++RALEAF LD WGVNVQ SGSPAN Y A++ H R+MGLDLP
Sbjct: 78 NQHIDEIEVLCQNRALEAFHLDPKQWGVNVQCLSGSPANLQVYQAIMPVHGRLMGLDLPH 137
Query: 1315 GGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLICGGSA 1136
GGHL+HGY T +KISA S YFE++PY+VN TG IDYD LE+ A FRPK+L+ G SA
Sbjct: 138 GGHLSHGYQTP-QRKISAVSTYFETMPYRVNIDTGLIDYDTLEKNAQLFRPKVLVAGTSA 196
Query: 1135 YPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPRA 956
Y R DY R+R +AD VGA L+ DMAHISGL+A++ +PF Y DVVTTTTHKSLRGPR
Sbjct: 197 YCRLIDYERMRKIADSVGAYLVVDMAHISGLIASEVIPSPFLYADVVTTTTHKSLRGPRG 256
Query: 955 GMIFYRKGPKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANTPGF 776
MIF+R+G + + +YD EDKINF+VFP QGGPHNH I ALAVALKQA +P F
Sbjct: 257 AMIFFRRGVRSVDAKTGKETLYDLEDKINFSVFPGHQGGPHNHTITALAVALKQAASPEF 316
Query: 775 KVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCDITL 596
K Y ++V ANA AL L GY +V+ GT++H+VL DLRP+G+ G +VE L + +IT
Sbjct: 317 KEYQQKVVANAKALEKKLKELGYKLVSDGTDSHMVLVDLRPIGVDGARVEFLLEQINITC 376
Query: 595 NKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQ----KEHG 428
NKNAV GD SAL PGG+RIGTPAMTSRG E DFE + F+ +V L IQ KE
Sbjct: 377 NKNAVPGDKSALTPGGLRIGTPAMTSRGFGEADFEKVAVFVDEAVKLCKEIQASLPKEAN 436
Query: 427 KLLKDFNKGLVNN--KEIEELKADVEKFAASYEMP 329
K KDF + + I ELK ++ ++ ++ +P
Sbjct: 437 K-QKDFKAKIATSDIPRINELKQEIAAWSNTFPLP 470
>sp|O13426|GLYC_CANAL Serine hydroxymethyltransferase, cytosolic OS=Candida
albicans GN=SHM2 PE=1 SV=3
Length = 470
Score = 469 bits (1205), Expect = 4e-131
Identities = 244/454 (53%), Positives = 317/454 (69%), Gaps = 9/454 (1%)
Frame = -3
Query: 1675 LVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNRYYGG 1496
L DPE+ +I+ E RQ I LIASENFT+ AV +ALG+ + NKYSEG PG RYYGG
Sbjct: 18 LKDTDPEVDQIIKDEIDRQQHSIVLIASENFTTTAVFDALGTPMCNKYSEGYPGARYYGG 77
Query: 1495 NEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPS 1316
NE I +E LC+ RAL+AF L WGVNVQ SGSPAN Y A+++PH+R+MGLDLP
Sbjct: 78 NEHIHRMELLCQERALKAFGLTPDKWGVNVQTLSGSPANLQVYQAIMKPHERLMGLDLPH 137
Query: 1315 GGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLICGGSA 1136
GGHL+HGY T +KISA S YFE++PY+V+ TG IDYD LE+ A+ +RPK+L+ G SA
Sbjct: 138 GGHLSHGYQTD-SRKISAVSTYFETMPYRVDLETGLIDYDMLEKTAVLYRPKVLVAGTSA 196
Query: 1135 YPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPRA 956
Y R DY R+R +ADKVGA L+ DMAHISGL+AA +PFEY D+VTTTTHKSLRGPR
Sbjct: 197 YCRLIDYKRMREIADKVGAYLVVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRG 256
Query: 955 GMIFYRKGPKP--PKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANTP 782
MIF+R+G + PK GQ +YD E+ INF+VFP QGGPHNH I ALA ALKQANTP
Sbjct: 257 AMIFFRRGVRSVNPKTGQE--ILYDLENPINFSVFPGHQGGPHNHTIAALATALKQANTP 314
Query: 781 GFKVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCDI 602
FK Y +QV NA AL + KGY +V+ GT++H+VL L+ + G +VE +C+ +I
Sbjct: 315 EFKEYQEQVLKNAKALESEFTKKGYKLVSDGTDSHMVLVSLKDKQIDGARVETVCEKINI 374
Query: 601 TLNKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKEHGK- 425
LNKN++ GD SAL PGGVRIG PAMT+RGL E+DF+ I ++ +V +Q + K
Sbjct: 375 ALNKNSIPGDKSALVPGGVRIGAPAMTTRGLGEEDFKKIVSYIDFAVNYAKEVQSQLPKD 434
Query: 424 --LLKDFNKGLVNNKE-IEELKADVEKFAASYEM 332
LKDF + + E ++ ++ ++ ++A S+ +
Sbjct: 435 ANKLKDFKNAVSGDSEKLKAVRDEIYQWAGSFPL 468
>sp|P37291|GLYC_YEAST Serine hydroxymethyltransferase, cytosolic
OS=Saccharomyces cerevisiae GN=SHM2 PE=1 SV=2
Length = 469
Score = 469 bits (1205), Expect = 4e-131
Identities = 241/452 (53%), Positives = 310/452 (68%), Gaps = 5/452 (1%)
Frame = -3
Query: 1675 LVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNRYYGG 1496
LV DPE+ +I+ E RQ I+LIASENFTS +V +ALG+ L+NKYSEG PG RYYGG
Sbjct: 17 LVDTDPEVDSIIKDEIERQKHSIDLIASENFTSTSVFDALGTPLSNKYSEGYPGARYYGG 76
Query: 1495 NEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPS 1316
NE ID +E LC+ RAL+AF + WGVNVQ SGSPAN Y A+++PH+R+MGL LP
Sbjct: 77 NEHIDRMEILCQQRALKAFHVTPDKWGVNVQTLSGSPANLQVYQAIMKPHERLMGLYLPD 136
Query: 1315 GGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLICGGSA 1136
GGHL+HGY T +KISA S YFES PY+VN TG IDYD LE+ A+ +RPK+L+ G SA
Sbjct: 137 GGHLSHGYATE-NRKISAVSTYFESFPYRVNPETGIIDYDTLEKNAILYRPKVLVAGTSA 195
Query: 1135 YPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPRA 956
Y R DY R+R +ADK GA L+ DMAHISGL+AA +PFEY D+VTTTTHKSLRGPR
Sbjct: 196 YCRLIDYKRMREIADKCGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRG 255
Query: 955 GMIFYRKGPKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANTPGF 776
MIF+R+G + + +YD E+ INF+VFP QGGPHNH I ALA ALKQA TP F
Sbjct: 256 AMIFFRRGVRSINPKTGKEVLYDLENPINFSVFPGHQGGPHNHTIAALATALKQAATPEF 315
Query: 775 KVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCDITL 596
K Y QV NA AL + GY +V+ GT++H+VL LR G+ G +VE +C+ +I L
Sbjct: 316 KEYQTQVLKNAKALESEFKNLGYRLVSNGTDSHMVLVSLREKGVDGARVEYICEKINIAL 375
Query: 595 NKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKEHGK--- 425
NKN++ GD SAL PGGVRIG PAMT+RG+ E+DF I ++++++V +Q+ K
Sbjct: 376 NKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFHRIVQYINKAVEFAQQVQQSLPKDAC 435
Query: 424 LLKDFNKGLVNNKEI-EELKADVEKFAASYEM 332
LKDF + ++ K ++ +A Y +
Sbjct: 436 RLKDFKAKVDEGSDVLNTWKKEIYDWAGEYPL 467
>sp|Q6FUP6|GLYC_CANGA Serine hydroxymethyltransferase, cytosolic OS=Candida
glabrata GN=SHM2 PE=3 SV=1
Length = 469
Score = 468 bits (1203), Expect = 7e-131
Identities = 249/454 (54%), Positives = 309/454 (68%), Gaps = 9/454 (1%)
Frame = -3
Query: 1675 LVTVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNRYYGG 1496
L DPE+ +I+ E RQ I+LIASENFT+ +V +ALG+ L NKYSEG PG RYYGG
Sbjct: 17 LSETDPEVEQIIKDEVDRQKHSIDLIASENFTTTSVFDALGTPLCNKYSEGYPGARYYGG 76
Query: 1495 NEFIDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPS 1316
NE ID IE LC+ RALEAF + WGVNVQ SGSPAN Y AL++PH+R+MGL LP
Sbjct: 77 NEHIDRIERLCQQRALEAFHVTPDRWGVNVQTLSGSPANLQVYQALMKPHERLMGLYLPD 136
Query: 1315 GGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLICGGSA 1136
GGHL+HGY T +KISA S YFES PY+VN TG IDYD LE+ A+ +RPK+L+ G SA
Sbjct: 137 GGHLSHGYATE-NRKISAVSTYFESFPYRVNPETGIIDYDTLEKNAILYRPKILVAGTSA 195
Query: 1135 YPRDWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPRA 956
Y R DY R+R +ADK GA L+ DMAHISGLVAA +PFEY D+VTTTTHKSLRGPR
Sbjct: 196 YCRLIDYKRMREIADKCGAYLMVDMAHISGLVAAGVIPSPFEYADIVTTTTHKSLRGPRG 255
Query: 955 GMIFYRKGPKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANTPGF 776
MIF+R+G + + + YD E+ INF+VFP QGGPHNH I ALA ALKQA TP F
Sbjct: 256 AMIFFRRGIRSVNQKTGKEIPYDLENPINFSVFPGHQGGPHNHTIAALATALKQAATPEF 315
Query: 775 KVYAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCDITL 596
K Y QV NA AL N GY +V+ GT++H+VL LR G+ G +VE +C+ +I L
Sbjct: 316 KEYQTQVLKNAKALENEFQTLGYRLVSNGTDSHMVLVSLREKGVDGARVEYVCEKINIAL 375
Query: 595 NKNAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQ----KEHG 428
NKN++ GD SAL PGGVRIG PAMT+RG+ E+DF I ++ ++V Q KE
Sbjct: 376 NKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFHRIVRYIDQAVKFAEQTQSSLPKEAN 435
Query: 427 KLLKDFNKGLVNN--KEIEELKADVEKFAASYEM 332
K LKDF K V+ ++ LK ++ + A Y +
Sbjct: 436 K-LKDF-KAKVDEIADQLAPLKKEIYDWTAEYPL 467
>sp|Q6CLQ5|GLYM_KLULA Serine hydroxymethyltransferase, mitochondrial
OS=Kluyveromyces lactis GN=SHM1 PE=3 SV=1
Length = 498
Score = 465 bits (1196), Expect = 5e-130
Identities = 235/457 (51%), Positives = 312/457 (68%), Gaps = 10/457 (2%)
Frame = -3
Query: 1666 VDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNRYYGGNEF 1487
+DPE++D++ KE++RQ I LI SENFTS +V++ LGS + NKYSEG PG RYYGGN+F
Sbjct: 44 IDPEMYDILTKERKRQKHSITLIPSENFTSKSVMDLLGSEMQNKYSEGYPGERYYGGNQF 103
Query: 1486 IDLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGH 1307
ID+ E+LC+ RALE + LD WGVNVQP SG+PAN AY+A+++ +DR+MGLDLP GGH
Sbjct: 104 IDMAESLCQKRALELYNLDPQLWGVNVQPLSGAPANLYAYSAVMETNDRLMGLDLPHGGH 163
Query: 1306 LTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLICGGSAYPR 1127
L+HGY G KIS S YF+++PY V+ TG IDYD L + + FRPK+++ G SAY R
Sbjct: 164 LSHGYQLPSGTKISYISKYFQTMPYHVDSQTGIIDYDFLSKTSKLFRPKVIVAGASAYSR 223
Query: 1126 DWDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPRAGMI 947
DY R + +AD GA L+ DMAHISGLVAA +PFEY D+VTTTTHKSLRGPR MI
Sbjct: 224 VLDYKRFKEIADACGAYLMSDMAHISGLVAAGVTRSPFEYSDIVTTTTHKSLRGPRGAMI 283
Query: 946 FYRKG-PKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANTPGFKV 770
FYRKG K KKG+ +YD + +INF+VFP QGGPHNH I ALAVALKQA TP FK
Sbjct: 284 FYRKGVRKVTKKGKE--VLYDLDKRINFSVFPGHQGGPHNHTISALAVALKQAATPEFKE 341
Query: 769 YAKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCDITLNK 590
Y V NA L+ KG+ +V+GGT+ HL+L +L LG+ G ++E L + +I NK
Sbjct: 342 YQAAVVENARIFGEELVKKGFELVSGGTDTHLILINLSNLGIDGARLETLLENINIAANK 401
Query: 589 NAVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKEHGKLLKDF 410
N + GD SAL P G+R+GTPAMT+RG ++F + ++ R+V L + I+ + KD
Sbjct: 402 NTIPGDKSALFPSGLRVGTPAMTTRGFGPQEFAQVAAYIDRAVKLAIGIKSQESPDAKDA 461
Query: 409 NKGLVNNKE-------IEELKADVEKFAASYEMPGFL 320
L + KE +++L +V ++ + +PG L
Sbjct: 462 RSKLASFKELCKESDQVKQLADEVYQWVGEFPVPGEL 498
>sp|Q758F0|GLYM_ASHGO Serine hydroxymethyltransferase, mitochondrial OS=Ashbya
gossypii GN=SHM1 PE=3 SV=1
Length = 497
Score = 463 bits (1191), Expect = 2e-129
Identities = 235/456 (51%), Positives = 309/456 (67%), Gaps = 10/456 (2%)
Frame = -3
Query: 1663 DPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGMPGNRYYGGNEFI 1484
DPE++D++ KE+ RQ R I LI SENFTS AV+ LGS + NKYSEG PG RYYGGN++I
Sbjct: 44 DPEMYDILTKERSRQKRSITLIPSENFTSVAVMNLLGSEMQNKYSEGYPGQRYYGGNQYI 103
Query: 1483 DLIENLCRSRALEAFRLDSASWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHL 1304
D+ E+LC+ RALE + LD A WGVNVQ SG+PAN AY+A+++ DR+MGLDLP GGHL
Sbjct: 104 DMAESLCQKRALELYGLDPAKWGVNVQSLSGAPANLYAYSAIMEVGDRMMGLDLPHGGHL 163
Query: 1303 THGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKAMDFRPKLLICGGSAYPRD 1124
+HGY G KIS S YF+++ Y+V+ TG +DYD L E + FRPK+++ G SAY R
Sbjct: 164 SHGYQLQNGNKISYISKYFQTMAYRVDPATGLVDYDTLSETSKLFRPKVIVAGTSAYARV 223
Query: 1123 WDYARLRAVADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPRAGMIF 944
DY R R +AD GA LL DMAH+SGLVAA +PFEY D+VTTTTHKSLRGPR MIF
Sbjct: 224 LDYKRFREIADACGAYLLSDMAHVSGLVAAGVHPSPFEYSDIVTTTTHKSLRGPRGAMIF 283
Query: 943 YRKG-PKPPKKGQAEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANTPGFKVY 767
YRKG K KKG +YD + +INF+VFPA QGGPHNH I ALAVALKQA TP FK Y
Sbjct: 284 YRKGIRKVTKKGTE--IMYDLDKRINFSVFPAHQGGPHNHTISALAVALKQAATPEFKNY 341
Query: 766 AKQVKANAVALANYLMGKGYSIVTGGTENHLVLWDLRPLGLTGNKVEKLCDLCDITLNKN 587
V NA L +G+S+V+GGT+ HL+L DL P+G+ G+++E + + +I NKN
Sbjct: 342 QTAVVENAKVFGEELSKRGFSLVSGGTDTHLLLIDLSPMGIDGSRLETILERLNIAANKN 401
Query: 586 AVFGDSSALAPGGVRIGTPAMTSRGLVEKDFEMIGEFLSRSVTLTLNIQKEHGKLLKD-- 413
+ GD SAL P G+R+GTPAMT+RG +F + +++ +V L + ++ + KD
Sbjct: 402 TIPGDKSALYPSGLRVGTPAMTTRGFGPAEFGRVAAYINEAVKLAIGLKSQEPVDAKDAK 461
Query: 412 -----FNKGLVNNKEIEELKADVEKFAASYEMPGFL 320
F ++++ +L +V + A Y +PG L
Sbjct: 462 TRLAHFKSFCAESEQVTKLANEVADWVAQYPVPGEL 497
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,939,596,409
Number of Sequences: 518415
Number of Extensions: 42939596409
Number of Successful Extensions: 329982924
Number of sequences better than 0.0: 0
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