BLASTX 7.6.2
Query= UN10832 /QuerySize=2745
(2744 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9LIR8|FBK67_ARATH F-box/kelch-repeat protein At3g23880 OS=Ar... 607 2e-172
sp|Q3SWX0|NIPA2_BOVIN Magnesium transporter NIPA2 OS=Bos taurus ... 300 3e-080
sp|Q8N8Q9|NIPA2_HUMAN Magnesium transporter NIPA2 OS=Homo sapien... 299 7e-080
sp|Q5R7Q3|NIPA2_PONAB Magnesium transporter NIPA2 OS=Pongo abeli... 299 7e-080
sp|Q9JJC8|NIPA2_MOUSE Magnesium transporter NIPA2 OS=Mus musculu... 293 7e-078
sp|Q5RDB8|NIPA3_PONAB Magnesium transporter NIPA3 OS=Pongo abeli... 292 9e-078
sp|Q8BMW7|NIPA3_MOUSE Magnesium transporter NIPA3 OS=Mus musculu... 290 6e-077
sp|Q6NVV3|NIPA3_HUMAN Magnesium transporter NIPA3 OS=Homo sapien... 289 8e-077
sp|Q0D2K0|NIPA4_HUMAN Magnesium transporter NIPA4 OS=Homo sapien... 285 1e-075
sp|Q8BZF2|NIPA4_MOUSE Magnesium transporter NIPA4 OS=Mus musculu... 278 2e-073
sp|Q7RTP0|NIPA1_HUMAN Magnesium transporter NIPA1 OS=Homo sapien... 219 1e-055
sp|Q8BHK1|NIPA1_MOUSE Magnesium transporter NIPA1 OS=Mus musculu... 219 1e-055
sp|Q9H841|NPAL2_HUMAN NIPA-like protein 2 OS=Homo sapiens GN=NIP... 152 2e-035
sp|Q91WC7|NPAL2_MOUSE NIPA-like protein 2 OS=Mus musculus GN=Nip... 146 1e-033
sp|Q5RD30|NPAL3_PONAB NIPA-like protein 3 OS=Pongo abelii GN=NIP... 137 5e-031
sp|Q6P499|NPAL3_HUMAN NIPA-like protein 3 OS=Homo sapiens GN=NIP... 137 6e-031
sp|Q8BGN5|NPAL3_MOUSE NIPA-like protein 3 OS=Mus musculus GN=Nip... 137 6e-031
>sp|Q9LIR8|FBK67_ARATH F-box/kelch-repeat protein At3g23880 OS=Arabidopsis
thaliana GN=At3g23880 PE=2 SV=1
Length = 364
Score = 607 bits (1563), Expect = 2e-172
Identities = 302/368 (82%), Positives = 322/368 (87%), Gaps = 9/368 (2%)
Frame = +1
Query: 55 TQSFFSLPNLPPEMMEEILLRLPVKSLRRFKCVCLSWRSLISESLFTLKHALMLEASKAT 234
T+ FS NLP EMMEEILLRLPVKSL RFKCVC SWRSLISE+LF LKHAL+LE SKAT
Sbjct: 5 TREMFSPHNLPLEMMEEILLRLPVKSLTRFKCVCSSWRSLISETLFALKHALILETSKAT 64
Query: 235 TYKKSPYGVITTSRYHLKSCCVHSLYNEPMANVFEHDGELLGRDYYQVVGTCNGLVCFHV 414
T KSPYGVITTSRYHLKSCC+HSLYN V EHDGELLGRDYYQVVGTC+GLVCFHV
Sbjct: 65 TSTKSPYGVITTSRYHLKSCCIHSLYNASTVYVSEHDGELLGRDYYQVVGTCHGLVCFHV 124
Query: 415 DYNKSFYLWNPTIKVQQRLPGSDLETG-DEVVVNYGFGYDESEDDYKIVALLQQRHELKT 591
DY+KS YLWNPTIK+QQRL SDLET DE VV YGFGYDESEDDYK+VALLQQRH++K
Sbjct: 125 DYDKSLYLWNPTIKLQQRLSSSDLETSDDECVVTYGFGYDESEDDYKVVALLQQRHQVKI 184
Query: 592 EAMIYSTRQKLWRRRSSSNTCFPSGVVLANKSRSGIYINGTLNWAATNSSSSSSSVSTII 771
E IYSTRQKLWR SNT FPSGVV+A+KSRSGIYINGTLNWAAT+SSSS TII
Sbjct: 185 ETKIYSTRQKLWR----SNTSFPSGVVVADKSRSGIYINGTLNWAATSSSSS----WTII 236
Query: 772 SYDMSRDVFKELLGPGCCKRGCFTLTLGDLRGCLSMVCYCKGANADVWVMKEFGERDSWS 951
SYDMSRD FKEL GP CC RGCFT+TLGDLRGCLSMVCYCKGANADVWVMKEFGE SWS
Sbjct: 237 SYDMSRDEFKELPGPVCCGRGCFTMTLGDLRGCLSMVCYCKGANADVWVMKEFGEVYSWS 296
Query: 952 KLLSIPGLTEFVRPLWISRGLVVLLEFRSGLALYNCSTGKFQYPVSDSLSGCRDAKVYVK 1131
KLLSIPGLT+FVRPLWIS GLVVLLEFRSGLALYNCS G+F YPVS+S+SGCRDAKVY+K
Sbjct: 297 KLLSIPGLTDFVRPLWISDGLVVLLEFRSGLALYNCSNGRFHYPVSNSISGCRDAKVYLK 356
Query: 1132 TLVSPNDL 1155
T+VSPNDL
Sbjct: 357 TMVSPNDL 364
>sp|Q3SWX0|NIPA2_BOVIN Magnesium transporter NIPA2 OS=Bos taurus GN=NIPA2 PE=2
SV=1
Length = 360
Score = 300 bits (768), Expect = 3e-080
Identities = 146/295 (49%), Positives = 211/295 (71%), Gaps = 1/295 (0%)
Frame = -3
Query: 2385 GLVLAVSSSIFIGSSFIIKKKGLKKAGESG-VRAGEGGHGYLYEPWWWAGMITMIVGEVA 2209
GL LA+SSSIFIG SFI+KKKGL + G RAG+GGH YL E WWAG+++M GEVA
Sbjct: 13 GLGLAMSSSIFIGGSFILKKKGLLRLARKGSTRAGQGGHAYLKEWLWWAGLLSMGAGEVA 72
Query: 2208 NFAAYAFAPAILVTPLGALSIIFSAVLAHFILQEKLHMFGVLGCVLCVVGSTTIVLHAPH 2029
NFAAYAFAPA LVTPLGALS++ SA+L+ + L E+L++ G +GC+L ++GST +V+HAP
Sbjct: 73 NFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPK 132
Query: 2028 EQEIKSVKQVWKLAIEPGFLVYSAVILIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLT 1849
E+EI+++ ++ +PGF+V++ +++I L+LIF PR+G+T+++VY+ ICS++G+++
Sbjct: 133 EEEIETLNEMSHKLGDPGFVVFATLVVIVSLILIFVVGPRHGQTNILVYITICSVIGAVS 192
Query: 1848 VMSVKAVAIAIKLTFSEMNQFKYFQTWIFIIVVTVCCILQINYLNKALDTFNTAVISPVY 1669
V K + IAIK F+ ++ TWI ++ + VC QINYLN+ALD FNT++++P+Y
Sbjct: 193 VSCAKGLGIAIKELFAGKPVLQHPLTWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIY 252
Query: 1668 FVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTFLLHKTKDMGNSAS 1504
+V FTT I S I+FK+W + L GF TI+ G FLLH KD+ S S
Sbjct: 253 YVFFTTSVITCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSFSLS 307
>sp|Q8N8Q9|NIPA2_HUMAN Magnesium transporter NIPA2 OS=Homo sapiens GN=NIPA2 PE=2
SV=1
Length = 360
Score = 299 bits (765), Expect = 7e-080
Identities = 144/293 (49%), Positives = 210/293 (71%), Gaps = 1/293 (0%)
Frame = -3
Query: 2385 GLVLAVSSSIFIGSSFIIKKKGLKKAGESG-VRAGEGGHGYLYEPWWWAGMITMIVGEVA 2209
GL LA+SSSIFIG SFI+KKKGL + G +RAG+GGH YL E WWAG+++M GEVA
Sbjct: 13 GLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVA 72
Query: 2208 NFAAYAFAPAILVTPLGALSIIFSAVLAHFILQEKLHMFGVLGCVLCVVGSTTIVLHAPH 2029
NFAAYAFAPA LVTPLGALS++ SA+L+ + L E+L++ G +GC+L ++GST +V+HAP
Sbjct: 73 NFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPK 132
Query: 2028 EQEIKSVKQVWKLAIEPGFLVYSAVILIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLT 1849
E+EI+++ ++ +PGF+V++ +++I L+LIF PR+G+T+++VY+ ICS++G+ +
Sbjct: 133 EEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFS 192
Query: 1848 VMSVKAVAIAIKLTFSEMNQFKYFQTWIFIIVVTVCCILQINYLNKALDTFNTAVISPVY 1669
V VK + IAIK F+ ++ WI ++ + VC QINYLN+ALD FNT++++P+Y
Sbjct: 193 VSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIY 252
Query: 1668 FVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTFLLHKTKDMGNS 1510
+V FTT + S I+FK+W + L GF TI+ G FLLH KD+ S
Sbjct: 253 YVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSFS 305
>sp|Q5R7Q3|NIPA2_PONAB Magnesium transporter NIPA2 OS=Pongo abelii GN=NIPA2 PE=2
SV=1
Length = 360
Score = 299 bits (765), Expect = 7e-080
Identities = 144/293 (49%), Positives = 210/293 (71%), Gaps = 1/293 (0%)
Frame = -3
Query: 2385 GLVLAVSSSIFIGSSFIIKKKGLKKAGESG-VRAGEGGHGYLYEPWWWAGMITMIVGEVA 2209
GL LA+SSSIFIG SFI+KKKGL + G +RAG+GGH YL E WWAG+++M GEVA
Sbjct: 13 GLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVA 72
Query: 2208 NFAAYAFAPAILVTPLGALSIIFSAVLAHFILQEKLHMFGVLGCVLCVVGSTTIVLHAPH 2029
NFAAYAFAPA LVTPLGALS++ SA+L+ + L E+L++ G +GC+L ++GST +V+HAP
Sbjct: 73 NFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPK 132
Query: 2028 EQEIKSVKQVWKLAIEPGFLVYSAVILIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLT 1849
E+EI+++ ++ +PGF+V++ +++I L+LIF PR+G+T+++VY+ ICS++G+ +
Sbjct: 133 EEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFS 192
Query: 1848 VMSVKAVAIAIKLTFSEMNQFKYFQTWIFIIVVTVCCILQINYLNKALDTFNTAVISPVY 1669
V VK + IAIK F+ ++ WI ++ + VC QINYLN+ALD FNT++++P+Y
Sbjct: 193 VSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIY 252
Query: 1668 FVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTFLLHKTKDMGNS 1510
+V FTT + S I+FK+W + L GF TI+ G FLLH KD+ S
Sbjct: 253 YVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSFS 305
>sp|Q9JJC8|NIPA2_MOUSE Magnesium transporter NIPA2 OS=Mus musculus GN=Nipa2 PE=1
SV=1
Length = 359
Score = 293 bits (748), Expect = 7e-078
Identities = 141/293 (48%), Positives = 206/293 (70%), Gaps = 1/293 (0%)
Frame = -3
Query: 2385 GLVLAVSSSIFIGSSFIIKKKGLKKAGESG-VRAGEGGHGYLYEPWWWAGMITMIVGEVA 2209
GL LA++SSIFIG SFI+KKKGL + G +RAG+GGH YL E WWAG+++M GEVA
Sbjct: 13 GLGLAMTSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVA 72
Query: 2208 NFAAYAFAPAILVTPLGALSIIFSAVLAHFILQEKLHMFGVLGCVLCVVGSTTIVLHAPH 2029
NFAAYAFAPA LVTPLGALS++ SA+L+ + L E+L++ G +GC+L ++GST +V+HAP
Sbjct: 73 NFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPK 132
Query: 2028 EQEIKSVKQVWKLAIEPGFLVYSAVILIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLT 1849
E+EI+++ ++ +PGF+V++ ++I L+ IF PR+G+T+++VY+ ICS++G+ +
Sbjct: 133 EEEIETLNEMSHKLGDPGFVVFATFVVIVALIFIFVVGPRHGQTNILVYITICSVIGAFS 192
Query: 1848 VMSVKAVAIAIKLTFSEMNQFKYFQTWIFIIVVTVCCILQINYLNKALDTFNTAVISPVY 1669
V VK + IAIK + ++ WI + + VC QINYLN+ALD FNT++++P+Y
Sbjct: 193 VSCVKGLGIAIKELLAGKPVLQHPLAWILLFSLVVCVSTQINYLNRALDIFNTSIVTPIY 252
Query: 1668 FVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTFLLHKTKDMGNS 1510
+V FTT + S I+FK+W + L GF TI+ G FLLH KD+ S
Sbjct: 253 YVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSFS 305
>sp|Q5RDB8|NIPA3_PONAB Magnesium transporter NIPA3 OS=Pongo abelii GN=NIPAL1
PE=2 SV=1
Length = 410
Score = 292 bits (747), Expect = 9e-078
Identities = 141/289 (48%), Positives = 204/289 (70%), Gaps = 1/289 (0%)
Frame = -3
Query: 2385 GLVLAVSSSIFIGSSFIIKKKGLKKAGESGV-RAGEGGHGYLYEPWWWAGMITMIVGEVA 2209
GLVLAVSSSIFIGSSFI+KKKGL + G+ RAG+GGH YL E WW G+++M VGE A
Sbjct: 71 GLVLAVSSSIFIGSSFILKKKGLLQLASKGITRAGQGGHSYLKEWLWWVGLLSMGVGEAA 130
Query: 2208 NFAAYAFAPAILVTPLGALSIIFSAVLAHFILQEKLHMFGVLGCVLCVVGSTTIVLHAPH 2029
NFAAYAFAPA LVTPLGALS++ SA+L+ + L E L++ G +GC+L ++GST +V+HAP
Sbjct: 131 NFAAYAFAPATLVTPLGALSVLISAILSSYFLNEHLNIHGKIGCILSILGSTVMVIHAPQ 190
Query: 2028 EQEIKSVKQVWKLAIEPGFLVYSAVILIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLT 1849
E+E+ S+ ++ +PGF+ ++ ++ + LVLI P+ G+T+++VY+ ICSL+G+ +
Sbjct: 191 EEEVTSLHEMEMKLRDPGFISFAVIVTVISLVLILIVAPKKGQTNILVYISICSLIGAFS 250
Query: 1848 VMSVKAVAIAIKLTFSEMNQFKYFQTWIFIIVVTVCCILQINYLNKALDTFNTAVISPVY 1669
V SVK + IAIK +K+ ++ + V+ + QINYLNKALDTFNT++++P+Y
Sbjct: 251 VSSVKGLGIAIKELIEWKPVYKHPLVFVLLAVLVLSVTTQINYLNKALDTFNTSIVTPIY 310
Query: 1668 FVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTFLLHKTKD 1522
+V FT+ + S I+F++W + I L GF TI+ G FLLH K+
Sbjct: 311 YVFFTSMVVTCSAILFQEWYGMTAGDIIGTLSGFFTIIIGIFLLHAFKN 359
>sp|Q8BMW7|NIPA3_MOUSE Magnesium transporter NIPA3 OS=Mus musculus GN=Nipal1
PE=1 SV=2
Length = 416
Score = 290 bits (740), Expect = 6e-077
Identities = 141/289 (48%), Positives = 204/289 (70%), Gaps = 1/289 (0%)
Frame = -3
Query: 2385 GLVLAVSSSIFIGSSFIIKKKGLKKAGESGV-RAGEGGHGYLYEPWWWAGMITMIVGEVA 2209
GLVLA+SSS+FIGSSFI+KKKGL + + G+ RAG+GGH YL E WWAG+++M GE A
Sbjct: 71 GLVLAISSSVFIGSSFILKKKGLLQLADKGITRAGQGGHSYLKEWLWWAGLLSMGAGEAA 130
Query: 2208 NFAAYAFAPAILVTPLGALSIIFSAVLAHFILQEKLHMFGVLGCVLCVVGSTTIVLHAPH 2029
NFAAYAFAPA LVTPLGALS++ SA+L+ + L E+L++ G +GC+L V+GST +V+HAP
Sbjct: 131 NFAAYAFAPATLVTPLGALSVLISAILSSYFLNERLNIHGKIGCILSVLGSTVMVIHAPQ 190
Query: 2028 EQEIKSVKQVWKLAIEPGFLVYSAVILIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLT 1849
E E+ S+ ++ +PGF+ ++ +I + LVLI P+ G+T+++VY+ ICSL+G+ +
Sbjct: 191 EGEVTSLHEMEMKLRDPGFVSFAVIISVISLVLILIVAPKKGQTNILVYIAICSLIGAFS 250
Query: 1848 VMSVKAVAIAIKLTFSEMNQFKYFQTWIFIIVVTVCCILQINYLNKALDTFNTAVISPVY 1669
V SVK + IAIK +K +I + ++ + QINYLNKALDTFNT++++P+Y
Sbjct: 251 VSSVKGLGIAIKELLERKPVYKDPLFFILLTMLALSVTTQINYLNKALDTFNTSLVTPIY 310
Query: 1668 FVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTFLLHKTKD 1522
+V FT+ + S I+F++W I L GF TI++G FLLH K+
Sbjct: 311 YVFFTSMVVTCSAILFQEWYGMKAGDIIGTLSGFFTIINGIFLLHAFKN 359
>sp|Q6NVV3|NIPA3_HUMAN Magnesium transporter NIPA3 OS=Homo sapiens GN=NIPAL1
PE=2 SV=1
Length = 410
Score = 289 bits (739), Expect = 8e-077
Identities = 141/289 (48%), Positives = 202/289 (69%), Gaps = 1/289 (0%)
Frame = -3
Query: 2385 GLVLAVSSSIFIGSSFIIKKKGLKKAGESG-VRAGEGGHGYLYEPWWWAGMITMIVGEVA 2209
GLVLAVSSSIFIGSSFI+KKKGL + G RAG+GGH YL E WW G+++M GE A
Sbjct: 71 GLVLAVSSSIFIGSSFILKKKGLLQLASKGFTRAGQGGHSYLKEWLWWVGLLSMGAGEAA 130
Query: 2208 NFAAYAFAPAILVTPLGALSIIFSAVLAHFILQEKLHMFGVLGCVLCVVGSTTIVLHAPH 2029
NFAAYAFAPA LVTPLGALS++ SA+L+ + L E L++ G +GC+L ++GST +V+HAP
Sbjct: 131 NFAAYAFAPATLVTPLGALSVLISAILSSYFLNEHLNIHGKIGCILSILGSTVMVIHAPQ 190
Query: 2028 EQEIKSVKQVWKLAIEPGFLVYSAVILIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLT 1849
E+E+ S+ ++ +PGF+ ++ +I + LVLI P+ G+T+++VY+ ICSL+G+ +
Sbjct: 191 EEEVTSLHEMEMKLRDPGFISFAVIITVISLVLILIVAPKKGQTNILVYISICSLIGAFS 250
Query: 1848 VMSVKAVAIAIKLTFSEMNQFKYFQTWIFIIVVTVCCILQINYLNKALDTFNTAVISPVY 1669
V SVK + IAIK +K+ ++ + V+ + QINYLNKALDTFNT++++P+Y
Sbjct: 251 VSSVKGLGIAIKELIEWKPVYKHPLVFVLLAVLVLSVTTQINYLNKALDTFNTSLVTPIY 310
Query: 1668 FVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTFLLHKTKD 1522
+V FT+ + S I+F++W + I L GF TI+ G FLLH K+
Sbjct: 311 YVFFTSMVVTCSAILFQEWYGMTAGDIIGTLSGFFTIIIGIFLLHAFKN 359
>sp|Q0D2K0|NIPA4_HUMAN Magnesium transporter NIPA4 OS=Homo sapiens GN=NIPAL4
PE=1 SV=3
Length = 466
Score = 285 bits (728), Expect = 1e-075
Identities = 135/295 (45%), Positives = 207/295 (70%), Gaps = 1/295 (0%)
Frame = -3
Query: 2385 GLVLAVSSSIFIGSSFIIKKKGLKKAGESG-VRAGEGGHGYLYEPWWWAGMITMIVGEVA 2209
GL LA SS IGSS I+KKKGL + +G RA +GG GYL + WWAG +TM GEVA
Sbjct: 121 GLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDAMWWAGFLTMAAGEVA 180
Query: 2208 NFAAYAFAPAILVTPLGALSIIFSAVLAHFILQEKLHMFGVLGCVLCVVGSTTIVLHAPH 2029
NF AYAFAPA +VTPLGALS++ SA+L+ + L+E L++ G LGCV+CV GST +V+HAP
Sbjct: 181 NFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGSTVMVIHAPE 240
Query: 2028 EQEIKSVKQVWKLAIEPGFLVYSAVILIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLT 1849
E+++ ++ ++ + GF+V++ ++L++ L+LIF PRYG+ ++++Y+ ICS++G+ +
Sbjct: 241 EEKVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIIICSVIGAFS 300
Query: 1848 VMSVKAVAIAIKLTFSEMNQFKYFQTWIFIIVVTVCCILQINYLNKALDTFNTAVISPVY 1669
V +VK + I IK F + ++ +I +++ + Q+N+LN+ALD FNT+++ P+Y
Sbjct: 301 VAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLNRALDIFNTSLVFPIY 360
Query: 1668 FVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTFLLHKTKDMGNSAS 1504
+V FTT + +S+I+FK+W S S + IA L GFVTI+ G F+LH KD+ S +
Sbjct: 361 YVFFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVFMLHAFKDLDISCA 415
>sp|Q8BZF2|NIPA4_MOUSE Magnesium transporter NIPA4 OS=Mus musculus GN=Nipal4
PE=1 SV=1
Length = 406
Score = 278 bits (709), Expect = 2e-073
Identities = 128/290 (44%), Positives = 204/290 (70%), Gaps = 1/290 (0%)
Frame = -3
Query: 2385 GLVLAVSSSIFIGSSFIIKKKGLKKAGESG-VRAGEGGHGYLYEPWWWAGMITMIVGEVA 2209
G+ LA S IG+S I+KKKGL + +G RA GG+GYL +P WWAGM TM GEVA
Sbjct: 61 GVGLAFLSCFLIGTSVILKKKGLIRLVATGATRAVNGGYGYLKDPMWWAGMATMSAGEVA 120
Query: 2208 NFAAYAFAPAILVTPLGALSIIFSAVLAHFILQEKLHMFGVLGCVLCVVGSTTIVLHAPH 2029
NF AYAFAPA +VTPLGALS++ SA+ + + L E L++ G LGCV+C+ GST +V+HAP
Sbjct: 121 NFGAYAFAPATVVTPLGALSVLISAIFSSYCLGESLNLLGKLGCVICMAGSTVMVIHAPK 180
Query: 2028 EQEIKSVKQVWKLAIEPGFLVYSAVILIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLT 1849
E+++ +V ++ + GF+V++ +++++ L+LIF PRYG+ ++++Y+ ICS++GS +
Sbjct: 181 EEKVTTVAEMASKMKDTGFIVFAVLLVVSCLILIFIVAPRYGQRNILIYIIICSVIGSFS 240
Query: 1848 VMSVKAVAIAIKLTFSEMNQFKYFQTWIFIIVVTVCCILQINYLNKALDTFNTAVISPVY 1669
V +VK + + I+ F + ++ +I +++ + I+Q+N+LN+ALD FNT+++ P+Y
Sbjct: 241 VTAVKGLGVTIRNFFQGLPVVRHPLPYILSLILGLSIIIQVNFLNRALDIFNTSLVFPIY 300
Query: 1668 FVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTFLLHKTKDM 1519
+V FTT + +S+++FK+W + S + I L GFVTI+ G F+LH KD+
Sbjct: 301 YVFFTTVVVASSIVLFKEWYTMSAVDIVGTLSGFVTIILGVFMLHAFKDL 350
>sp|Q7RTP0|NIPA1_HUMAN Magnesium transporter NIPA1 OS=Homo sapiens GN=NIPA1 PE=1
SV=1
Length = 329
Score = 219 bits (556), Expect = 1e-055
Identities = 110/306 (35%), Positives = 183/306 (59%), Gaps = 9/306 (2%)
Frame = -3
Query: 2385 GLVLAVSSSIFIGSSFIIKKKGLKKAGESGVRAGEGGHGYLYEPWWWAGMITMIVGEVAN 2206
GL +AV SS+ GS+F+++KKG+ VRA G YL + WWAG I M VG++ N
Sbjct: 31 GLGVAVVSSLVNGSTFVLQKKGI-------VRAKRRGTSYLTDIVWWAGTIAMAVGQIGN 83
Query: 2205 FAAYAFAPAILVTPLGALSIIFSAVLAHFILQEKLHMFGVLGCVLCVVGSTTIVLHAPHE 2026
F AY P +LVTPLGAL + F ++LA ++L+EKL++ G LGC+L GS +++H+P
Sbjct: 84 FLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVVLIIHSPKS 143
Query: 2025 QEIKSVKQVWKLAIEPGFLVYSAVILIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLTV 1846
+ + + ++ + P F+ Y ++L+ +L+LIF+ P +G T+++VY+ ICSL+GS TV
Sbjct: 144 ESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISICSLLGSFTV 203
Query: 1845 MSVKAVAIAIK--LTFSEMNQFKYFQTWIFIIVVTVCCILQINYLNKALDTFNTAVISPV 1672
S K + +A + L + +Q + + V+ I+Q Y+NKAL+ F+++V +
Sbjct: 204 PSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECFDSSVFGAI 263
Query: 1671 YFVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTFLLHKTKDMGNSASGRGA 1492
Y+V+FTT ++AS I+F++W++ + CGF T+ G L+ K+ +
Sbjct: 264 YYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFNFNLGEMNK 323
Query: 1491 SSTPRD 1474
S+ D
Sbjct: 324 SNMKTD 329
>sp|Q8BHK1|NIPA1_MOUSE Magnesium transporter NIPA1 OS=Mus musculus GN=Nipa1 PE=1
SV=1
Length = 323
Score = 219 bits (556), Expect = 1e-055
Identities = 110/306 (35%), Positives = 183/306 (59%), Gaps = 9/306 (2%)
Frame = -3
Query: 2385 GLVLAVSSSIFIGSSFIIKKKGLKKAGESGVRAGEGGHGYLYEPWWWAGMITMIVGEVAN 2206
GL +AV SS+ GS+F+++KKG+ VRA G YL + WWAG I M VG++ N
Sbjct: 25 GLGVAVVSSLVNGSTFVLQKKGI-------VRAKRRGTSYLTDIVWWAGTIAMAVGQIGN 77
Query: 2205 FAAYAFAPAILVTPLGALSIIFSAVLAHFILQEKLHMFGVLGCVLCVVGSTTIVLHAPHE 2026
F AY P +LVTPLGAL + F ++LA ++L+EKL++ G LGC+L GS +++H+P
Sbjct: 78 FLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVVLIIHSPKS 137
Query: 2025 QEIKSVKQVWKLAIEPGFLVYSAVILIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLTV 1846
+ + + ++ + P F+ Y ++L+ +L+LIF+ P +G T+++VY+ ICSL+GS TV
Sbjct: 138 ESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISICSLLGSFTV 197
Query: 1845 MSVKAVAIAIK--LTFSEMNQFKYFQTWIFIIVVTVCCILQINYLNKALDTFNTAVISPV 1672
S K + +A + L + +Q + + V+ I+Q Y+NKAL+ F+++V +
Sbjct: 198 PSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECFDSSVFGAI 257
Query: 1671 YFVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTFLLHKTKDMGNSASGRGA 1492
Y+V+FTT ++AS I+F++W++ + CGF T+ G L+ K+ +
Sbjct: 258 YYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFNFNLGEMNK 317
Query: 1491 SSTPRD 1474
S+ D
Sbjct: 318 SNMKTD 323
>sp|Q9H841|NPAL2_HUMAN NIPA-like protein 2 OS=Homo sapiens GN=NIPAL2 PE=2 SV=1
Length = 368
Score = 152 bits (382), Expect = 2e-035
Identities = 85/288 (29%), Positives = 151/288 (52%), Gaps = 6/288 (2%)
Frame = -3
Query: 2385 GLVLAVSSSIFIGSSFIIKKKGLKKAGESGVRAGEGGHGYLYEPWWWAGMITMIVGEVAN 2206
G++LA+ ++ I S I+K + + E Y WW G++ M VGE N
Sbjct: 50 GVLLAILGNLVISISLNIQKYSHLQLAQQ-----EHPRPYFKSVLWWGGVLLMAVGETGN 104
Query: 2205 FAAYAFAPAILVTPLGALSIIFSAVLAHFILQEKLHMFGVLGCVLCVVGSTTIVLHAPHE 2026
FAAY FAP L+ PLG +S+ SA+++ L++ L +LG L G+ +V AP+
Sbjct: 105 FAAYGFAPITLIAPLGCVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYLLVNFAPNI 164
Query: 2025 QEIKSVKQVWKLAIEPGFLVYSAVILIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLTV 1846
+ S + V + FL+Y + ++ +L+++Y+ R G H+++ + + +++ SLTV
Sbjct: 165 TQAISARTVQYYLVGWQFLIYVILEILIFCILLYFYK-RKGMKHMVILLTLVAILASLTV 223
Query: 1845 MSVKAVAIAIKLTFSEMNQFKYFQTWIFIIVVTVCCILQINYLNKALDTFNTAVISPVYF 1666
+SVKAV+ I + + Q Y +I I++ C+ Q+ +LN+A +NT + PV
Sbjct: 224 ISVKAVSGMITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVNH 283
Query: 1665 VMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTFLLHKTKD 1522
+ FT IIA +I ++++ L + L G G FL+ + ++
Sbjct: 284 IFFTISAIIAGIIFYQEFLGAPFLTVFIYLFGCFLSFLGVFLVTRNRE 331
>sp|Q91WC7|NPAL2_MOUSE NIPA-like protein 2 OS=Mus musculus GN=Nipal2 PE=2 SV=1
Length = 383
Score = 146 bits (367), Expect = 1e-033
Identities = 86/288 (29%), Positives = 149/288 (51%), Gaps = 6/288 (2%)
Frame = -3
Query: 2385 GLVLAVSSSIFIGSSFIIKKKGLKKAGESGVRAGEGGHGYLYEPWWWAGMITMIVGEVAN 2206
G++LA+ ++ I S I+K + E Y W +G++ +GE N
Sbjct: 50 GVLLAILGNLVISISLNIQKYSHLHLAQK-----EHPKPYFKSVLWLSGVLLTALGETGN 104
Query: 2205 FAAYAFAPAILVTPLGALSIIFSAVLAHFILQEKLHMFGVLGCVLCVVGSTTIVLHAPHE 2026
FAAY AP L+ PLG +S+ SA+++ L+E L +LG L G+ +V AP+
Sbjct: 105 FAAYGVAPITLIAPLGCMSVTGSAIISVLFLKENLRASDLLGMTLAFAGTYLLVNFAPNI 164
Query: 2025 QEIKSVKQVWKLAIEPGFLVYSAVILIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLTV 1846
+ S + V + FLVY ++ I V ++ Y+ R G H++V + + +L+ SLTV
Sbjct: 165 TQAISARTVQYYFVGWQFLVY-VILEILVFCILLYFHKRKGMKHIVVLLTLVALLASLTV 223
Query: 1845 MSVKAVAIAIKLTFSEMNQFKYFQTWIFIIVVTVCCILQINYLNKALDTFNTAVISPVYF 1666
+SVKAV+ I L+ + Q Y +I ++++ C+ Q+ +LN+A + + + PV
Sbjct: 224 ISVKAVSGMITLSVTGKMQLTYAIFYIMLVIMIASCVFQVKFLNQATELYTMTTVVPVNH 283
Query: 1665 VMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTFLLHKTKD 1522
V FTT IIA +I ++++ + L + L G G FL+ + ++
Sbjct: 284 VFFTTSAIIAGIIFYQEFLGAAFLTVFIYLFGCFLSFLGVFLVTRNRE 331
>sp|Q5RD30|NPAL3_PONAB NIPA-like protein 3 OS=Pongo abelii GN=NIPAL3 PE=2 SV=1
Length = 406
Score = 137 bits (344), Expect = 5e-031
Identities = 82/300 (27%), Positives = 160/300 (53%), Gaps = 16/300 (5%)
Frame = -3
Query: 2397 DNINGLVLAVSSSIFIGSSFIIKKK-GLKKAGESGVRAGEGGHGYLYEPWWWAGMITMIV 2221
+N+ G +LA+ + + + ++K ++ AG RA Y WW G+ M++
Sbjct: 32 ENLIGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRA------YFKTKTWWLGLFLMLL 85
Query: 2220 GEVANFAAYAFAPAILVTPLGALSIIFSAVLAHFILQEK--------LHMFGVLGCVLCV 2065
GE+ FA+YAFAP L+ PL A+S+I SA++ ++EK ++ +GC L V
Sbjct: 86 GELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYILSFVGCGLAV 145
Query: 2064 VGSTTIVLHAPHEQEIKSVKQVWKLAIEPGFLVYSAVILIAVLVLIFYYEPRYGKTHLIV 1885
VG+ +V AP+ +E + + V + + FL+Y V +I +L+++Y+ + +++V
Sbjct: 146 VGTYLLVTFAPNSREKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEK-NANNIVV 204
Query: 1884 YVGICSLMGSLTVMSVKAVAIAIKLTFSEMNQFKYFQTWIFIIVVTVCCILQINYLNKAL 1705
+ + +L+GS+TV++VKAVA + L+ Q Y ++ + + + Q +L++A
Sbjct: 205 ILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQAS 264
Query: 1704 DTFNTAVISPVYFVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTFLLHKTK 1525
+++++I+ V +++ TT I A I + D+ + L I G + G FL+ + +
Sbjct: 265 QMYDSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFLITRNR 324
>sp|Q6P499|NPAL3_HUMAN NIPA-like protein 3 OS=Homo sapiens GN=NIPAL3 PE=1 SV=1
Length = 406
Score = 137 bits (343), Expect = 6e-031
Identities = 82/300 (27%), Positives = 159/300 (53%), Gaps = 16/300 (5%)
Frame = -3
Query: 2397 DNINGLVLAVSSSIFIGSSFIIKKK-GLKKAGESGVRAGEGGHGYLYEPWWWAGMITMIV 2221
+N+ G +LA+ + + + ++K ++ AG RA Y WW G+ M++
Sbjct: 32 ENLIGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRA------YFKTKTWWLGLFLMLL 85
Query: 2220 GEVANFAAYAFAPAILVTPLGALSIIFSAVLAHFILQEK--------LHMFGVLGCVLCV 2065
GE+ FA+YAFAP L+ PL A+S+I SA++ ++EK ++ +GC L V
Sbjct: 86 GELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAV 145
Query: 2064 VGSTTIVLHAPHEQEIKSVKQVWKLAIEPGFLVYSAVILIAVLVLIFYYEPRYGKTHLIV 1885
VG+ +V AP+ E + + V + + FL+Y V +I +L+++Y+ + +++V
Sbjct: 146 VGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEK-NANNIVV 204
Query: 1884 YVGICSLMGSLTVMSVKAVAIAIKLTFSEMNQFKYFQTWIFIIVVTVCCILQINYLNKAL 1705
+ + +L+GS+TV++VKAVA + L+ Q Y ++ + + + Q +L++A
Sbjct: 205 ILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQAS 264
Query: 1704 DTFNTAVISPVYFVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTFLLHKTK 1525
+++++I+ V +++ TT I A I + D+ + L I G + G FL+ + +
Sbjct: 265 QMYDSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFLITRNR 324
>sp|Q8BGN5|NPAL3_MOUSE NIPA-like protein 3 OS=Mus musculus GN=Nipal3 PE=2 SV=1
Length = 410
Score = 137 bits (343), Expect = 6e-031
Identities = 79/300 (26%), Positives = 160/300 (53%), Gaps = 16/300 (5%)
Frame = -3
Query: 2397 DNINGLVLAVSSSIFIGSSFIIKKK-GLKKAGESGVRAGEGGHGYLYEPWWWAGMITMIV 2221
+N+ G +LA+ + + + ++K ++ AG RA Y WW G++ +++
Sbjct: 36 ENLIGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRA------YFKTKTWWLGLLLLLL 89
Query: 2220 GEVANFAAYAFAPAILVTPLGALSIIFSAVLAHFILQEK--------LHMFGVLGCVLCV 2065
GE+ FA+YAFAP L+ PL A+S+I SA++ ++EK ++ +GC L +
Sbjct: 90 GELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFVRRYVLSFVGCGLAI 149
Query: 2064 VGSTTIVLHAPHEQEIKSVKQVWKLAIEPGFLVYSAVILIAVLVLIFYYEPRYGKTHLIV 1885
VG+ +V AP+ E + + + + + FL+Y V ++ +L+++Y+ R + ++V
Sbjct: 150 VGTYLLVTFAPNSHEKMTGENIARHLVSWPFLLYMLVAIVLFCLLLYFYKERNANS-IVV 208
Query: 1884 YVGICSLMGSLTVMSVKAVAIAIKLTFSEMNQFKYFQTWIFIIVVTVCCILQINYLNKAL 1705
+ + +L+GS+TV++VKAV+ + L+ Q Y ++ + + I Q +L++A
Sbjct: 209 ILLLVALLGSMTVVTVKAVSGMLVLSIQGNLQLDYPIFYVMFVCMVATAIYQATFLSEAS 268
Query: 1704 DTFNTAVISPVYFVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTFLLHKTK 1525
+++++I+ V +++ TT I A I + D+ + L I G + G FL+ + +
Sbjct: 269 QIYDSSLIASVGYILSTTAAITAGAIFYLDFLGEEALHICMFALGCLIAFLGVFLITRNR 328
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,894,514,945
Number of Sequences: 518415
Number of Extensions: 45894514945
Number of Successful Extensions: 338263929
Number of sequences better than 0.0: 0
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