BLASTX 7.6.2
Query= UN11361 /QuerySize=1425
(1424 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9LYT3|TT12_ARATH Protein TRANSPARENT TESTA 12 OS=Arabidopsis... 374 1e-102
sp|A1L1P9|S47A1_DANRE Multidrug and toxin extrusion protein 1 OS... 188 1e-046
sp|Q8K0H1|S47A1_MOUSE Multidrug and toxin extrusion protein 1 OS... 188 1e-046
sp|A7KAU2|S47A1_RABIT Multidrug and toxin extrusion protein 1 OS... 186 4e-046
sp|Q9USK3|YJ2D_SCHPO Uncharacterized transporter C4B3.13 OS=Schi... 183 4e-045
sp|A4IIS8|S47A1_XENTR Multidrug and toxin extrusion protein 1 OS... 181 1e-044
sp|Q96FL8|S47A1_HUMAN Multidrug and toxin extrusion protein 1 OS... 181 1e-044
sp|Q5I0E9|S47A1_RAT Multidrug and toxin extrusion protein 1 OS=R... 180 2e-044
sp|Q5RFD2|S47A1_PONAB Multidrug and toxin extrusion protein 1 OS... 178 1e-043
sp|Q3V050|S47A2_MOUSE Multidrug and toxin extrusion protein 2 OS... 176 6e-043
sp|Q10085|YAO6_SCHPO Uncharacterized transporter C11D3.06 OS=Sch... 161 1e-038
sp|Q9UT92|YL47_SCHPO Uncharacterized transporter C323.07c OS=Sch... 156 6e-037
sp|Q05497|YD338_YEAST Uncharacterized transporter YDR338C OS=Sac... 146 5e-034
sp|Q98D15|NORM_RHILO Probable multidrug resistance protein norM ... 101 2e-020
sp|A6TA11|MDTK_KLEP7 Multidrug resistance protein mdtK OS=Klebsi... 86 5e-016
sp|B5XWL3|MDTK_KLEP3 Multidrug resistance protein mdtK OS=Klebsi... 82 7e-015
sp|Q9I3Y3|PMPM_PSEAE Multidrug resistance protein pmpM OS=Pseudo... 80 3e-014
sp|Q7NXN3|NORM_CHRVO Probable multidrug resistance protein norM ... 75 8e-013
sp|Q8YFD7|NORM_BRUME Probable multidrug resistance protein norM ... 55 1e-006
sp|Q8G2I1|NORM_BRUSU Probable multidrug resistance protein norM ... 55 1e-006
>sp|Q9LYT3|TT12_ARATH Protein TRANSPARENT TESTA 12 OS=Arabidopsis thaliana
GN=TT12 PE=2 SV=1
Length = 507
Score = 374 bits (958), Expect = 1e-102
Identities = 178/372 (47%), Positives = 256/372 (68%)
Frame = +2
Query: 2 HGAHRYDMLGVYLQRSTVVLIITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLP 181
+GA +Y +G+ QR+ V+ + + ++ L+ +S P+L T+G+ +A +F GM+P
Sbjct: 121 YGARQYSSMGIICQRAMVLHLAAAVFLTFLYWYSGPILKTMGQSVAIAHEGQIFARGMIP 180
Query: 182 VIFAYAVNFPIQKFLQAQSIVTPSAYISAAALVIHLVLSWVAVYRLGLGLLALSLVHSFS 361
I+A+A+ P+Q+FLQAQ+IV P AY+S ++H +L+W+ L GLL +L+ SFS
Sbjct: 181 QIYAFALACPMQRFLQAQNIVNPLAYMSLGVFLLHTLLTWLVTNVLDFGLLGAALILSFS 240
Query: 362 WWIIVGAQIVYIKMSPRCRRSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILVLL 541
WW++V +YI MSP C+ +W GFS +AF G+W +F+L+ ASAVMLCLE WY+Q LV++
Sbjct: 241 WWLLVAVNGMYILMSPNCKETWTGFSTRAFRGIWPYFKLTVASAVMLCLEIWYNQGLVII 300
Query: 542 AGLLRDPEIALDSLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVTTS 721
+GLL +P I+LD+++ICM +G +AA SVRVSNELGAGNPR A S VV
Sbjct: 301 SGLLSNPTISLDAISICMYYLNWDMQFMLGLSAAISVRVSNELGAGNPRVAMLSVVVVNI 360
Query: 722 VSFLLAVFEAIVVMSWRNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVAVG 901
+ L++ ++V+ +R LS FT V AV+DL P LA++I LNGIQP+LSGVA+G
Sbjct: 361 TTVLISSVLCVIVLVFRVGLSKAFTSDAEVIAAVSDLFPLLAVSIFLNGIQPILSGVAIG 420
Query: 902 CGWQAFVAYVNIGCYYVVGIPIGFVLGFTYDMGAKGIWTGMIGGTLMQTIILVVVTLRTD 1081
GWQA VAYVN+ YYV+G+PIG VLGF +G GIW GMI G ++QT+ L+V+TL+T+
Sbjct: 421 SGWQAVVAYVNLVTYYVIGLPIGCVLGFKTSLGVAGIWWGMIAGVILQTLTLIVLTLKTN 480
Query: 1082 WDKEVEKASSRL 1117
W EVE A+ R+
Sbjct: 481 WTSEVENAAQRV 492
>sp|A1L1P9|S47A1_DANRE Multidrug and toxin extrusion protein 1 OS=Danio rerio
GN=slc47a1 PE=2 SV=1
Length = 590
Score = 188 bits (475), Expect = 1e-046
Identities = 108/371 (29%), Positives = 192/371 (51%), Gaps = 4/371 (1%)
Frame = +2
Query: 5 GAHRYDMLGVYLQRSTVVLIITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLPV 184
G++ +GV LQR ++L++ C P L + ++P+L + + VAS++ L+V +P
Sbjct: 123 GSNNLKRVGVILQRGILILLLACFPCWALLINTEPILLAVRQSPNVASLSQLYVKIFMPA 182
Query: 185 IFAYAVNFPIQ-KFLQAQSIVTPSAYISAAALVIHLVLSWVAVYRLGLGLLALSLVHSFS 361
+ A A + +Q ++LQ Q I+ P AA +++ ++++V ++ L LG+ + ++ S
Sbjct: 183 LPA-AFMYQLQGRYLQNQGIIWPQVITGAAGNILNALINYVFLHLLELGVAGSAAANTIS 241
Query: 362 WWIIVGAQIVYIKMSPRCRRSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILVLL 541
+ + VYI+ + +W+G+S + F RL+ S +MLC+E W +I L
Sbjct: 242 QYSLAVFLYVYIRWKNLHKATWDGWSRDCLQEWGAFIRLALPSMLMLCVEWWTYEIGGFL 301
Query: 542 AGLLRDPEIALDSLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVTTS 721
AGL+ + E+ S + ++ +++M +GF AASVRV N LGAGN A S V
Sbjct: 302 AGLISETELGAQS--VVYELATIAYMFPLGFAVAASVRVGNALGAGNTERAKLSAKVALV 359
Query: 722 VSFLLAVFEAIVVMSWRNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVAVG 901
L++ A ++ ++V++Y+FT + V+ + + + I + G+ G
Sbjct: 360 CGVLVSCVVATLIGCTKDVIAYIFTTEEEIVSRVSQVMIMYGFFHLFDAIAGITGGIVRG 419
Query: 902 CGWQAFVAYVNIGCYYVVGIPIGFVLGFTYDMGAKGIWTGMIGGTLMQTIILVVVTLRTD 1081
G Q A NI YY VG P G L F MG G+W G G +Q++ +++ + D
Sbjct: 420 AGKQLLGALCNIVGYYFVGFPTGVSLMFALSMGIIGLWIGFFGCVFLQSLFFIILIYKLD 479
Query: 1082 WDKEVEKASSR 1114
W K ++A R
Sbjct: 480 WKKATQEALIR 490
>sp|Q8K0H1|S47A1_MOUSE Multidrug and toxin extrusion protein 1 OS=Mus musculus
GN=Slc47a1 PE=1 SV=2
Length = 567
Score = 188 bits (475), Expect = 1e-046
Identities = 108/368 (29%), Positives = 193/368 (52%), Gaps = 2/368 (0%)
Frame = +2
Query: 2 HGAHRYDMLGVYLQRSTVVLIITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLP 181
+G+ +GV LQR T++L++ C P LF+ ++ +L + V+ + +V +P
Sbjct: 104 YGSQNLKHVGVILQRGTLILLLCCFPCWALFINTEQILLLFRQDPDVSRLTQTYVMIFIP 163
Query: 182 VIFAYAVNFPIQKFLQAQSIVTPSAYISAAALVIHLVLSWVAVYRLGLGLLALSLVHSFS 361
+ A + K+L Q IV P AA +++ + ++V +Y L LG++ +L ++ S
Sbjct: 164 ALPAAFLYTLQVKYLLNQGIVLPQIMTGIAANLVNALANYVFLYHLHLGVMGSALANTIS 223
Query: 362 WWIIVGAQIVYIKMSPRCRRSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILVLL 541
+ + +YI + +W G+SW+ + F RL+ S +MLC+E W ++ L
Sbjct: 224 QFALAIFLFLYILWRRLHQATWGGWSWECLQDWASFLRLAIPSMLMLCIEWWAYEVGSFL 283
Query: 542 AGLLRDPEIALDSLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVTTS 721
+G+L E+ S I ++ + +M+ GF+ AA+VRV N LGAGN A S+ ++
Sbjct: 284 SGILGMVELGAQS--ITYELAIIVYMIPSGFSVAANVRVGNALGAGNIDQAKKSSAISLI 341
Query: 722 VSFLLAVFEAIVVMSWRNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVAVG 901
V+ L AV ++++ ++++ Y+FT + VA + P A++ + G+ G+ G
Sbjct: 342 VTELFAVTFCVLLLGCKDLVGYIFTTDRDIVALVAQVIPIYAVSHLFEGLACTCGGILRG 401
Query: 902 CGWQAFVAYVNIGCYYVVGIPIGFVLGFTYDMGAKGIWTGMIGGTLMQTIILVVVTLRTD 1081
G Q A VN YYV+G+PIG L F +G G+W+G+I T QT + R +
Sbjct: 402 TGNQKVGAIVNAIGYYVIGLPIGIALMFAAKLGVIGLWSGIIICTTCQTTCFLAFIARLN 461
Query: 1082 WDKEVEKA 1105
W + ++A
Sbjct: 462 WKRACQQA 469
>sp|A7KAU2|S47A1_RABIT Multidrug and toxin extrusion protein 1 OS=Oryctolagus
cuniculus GN=SLC47A1 PE=2 SV=1
Length = 568
Score = 186 bits (471), Expect = 4e-046
Identities = 107/368 (29%), Positives = 196/368 (53%), Gaps = 2/368 (0%)
Frame = +2
Query: 2 HGAHRYDMLGVYLQRSTVVLIITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLP 181
+G+ +GV LQR +++L++ CLP LF+ ++ +L + V+ + +V +P
Sbjct: 103 YGSRNLKHVGVILQRGSLILLLCCLPCWALFLNTQHILLLFRQDPAVSRLTQTYVTIFIP 162
Query: 182 VIFAYAVNFPIQKFLQAQSIVTPSAYISAAALVIHLVLSWVAVYRLGLGLLALSLVHSFS 361
+ A + K+L Q IV P AA +++ + +++ VY+L LG++ +L ++ +
Sbjct: 163 ALPATFLYTLQVKYLLNQGIVLPQVVTGVAANLVNALANYLFVYQLHLGVMGSALANTVA 222
Query: 362 WWIIVGAQIVYIKMSPRCRRSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILVLL 541
+ + +YI S + +W G+S + + FFRL+ S +MLC+E W +I L
Sbjct: 223 QFTLALLLFLYILRSKVYQATWGGWSLECLQDWASFFRLAIPSMLMLCMEWWAYEIGSFL 282
Query: 542 AGLLRDPEIALDSLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVTTS 721
+G+L E+ S + ++ + +M+ +G + A +VRV N LGAGN A S+ V
Sbjct: 283 SGILGMVELGAQS--VTYELAVIVYMIPMGLSVAVNVRVGNALGAGNIEQAKKSSAVALL 340
Query: 722 VSFLLAVFEAIVVMSWRNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVAVG 901
V+ L+AV ++++S ++++ Y+FT + VA ++P A++ + + G+ G
Sbjct: 341 VTELIAVVFCVMLLSCKDLVGYIFTSDRDIIALVAQVTPIYAVSHLFESLAGTSGGILRG 400
Query: 902 CGWQAFVAYVNIGCYYVVGIPIGFVLGFTYDMGAKGIWTGMIGGTLMQTIILVVVTLRTD 1081
G Q F A VN YYVVG+PIG L F +G G+W G++ + Q + + R +
Sbjct: 401 SGNQKFGAIVNAIGYYVVGLPIGIALMFAAKLGVIGLWLGIVVCAVSQAVCFLGFIARLN 460
Query: 1082 WDKEVEKA 1105
W K ++A
Sbjct: 461 WTKACQQA 468
>sp|Q9USK3|YJ2D_SCHPO Uncharacterized transporter C4B3.13 OS=Schizosaccharomyces
pombe GN=SPCC4B3.13 PE=2 SV=1
Length = 539
Score = 183 bits (463), Expect = 4e-045
Identities = 109/375 (29%), Positives = 197/375 (52%), Gaps = 5/375 (1%)
Frame = +2
Query: 5 GAHRYDMLGVYLQRSTVVLIITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLPV 184
G+ Y+M+G++LQR +L++ P+ L++ + +L L + A+ ++ M+
Sbjct: 167 GSGNYEMVGLHLQRILAILLLIQFPIFLIWWKIEGILLFLRQDPLTCMFAAKYMRVMMLA 226
Query: 185 IFAYAVNFPIQKFLQAQSIVTPSAYISAAALVIHLVLSWVAVYR--LGLGLLALSLVHSF 358
AYA+ +++FLQ Q I P YI A + I++ L+++ V+ +G G L + +
Sbjct: 227 SPAYALFEALKRFLQVQGIFHPVTYILAIVVPINIFLNYLFVWSPWVGFGFLGAPVAVAL 286
Query: 359 SWWIIVGAQIVYIKMSPRCRRSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILVL 538
+ W I+YI M R++W GFS +A + RL+ +M+C E W +++
Sbjct: 287 TLWSACAVLIIYI-MKVNGRQAWGGFSREALKNWGPLCRLAVPGVIMICSEYWAFELVTF 345
Query: 539 LAGLLRDPEIALDSLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVTT 718
+G+L E+A S+++ + S +S+ ++ G AAA+ RV N +GAGN + A +T V+
Sbjct: 346 ASGVLGTTELA--SMSVLSTTSTLSYNLAFGVAAAAATRVGNLIGAGNTKLAKLATHVSI 403
Query: 719 SVSFLLAVFEAIVVMSWRNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVAV 898
++ + V A+++ RN +Y+FT V VA + P +A+ + + Q V G+
Sbjct: 404 NLGAAIGVIIAVILFLTRNTWTYIFTSDKDVVALVATIIPLVALINIADNTQCVAGGLLR 463
Query: 899 GCGWQAFVAYVNIGCYYVVGIPIGFVLGFTYDMGAKGIWTGMIGGTLMQTIILVVVTLRT 1078
G G Q VN YY++G+P+ +L F D G G+W G+ L+ + +L
Sbjct: 464 GQGRQRIGGVVNFIAYYLLGLPVAIILCFKLDWGLYGLWIGIGAAILIIAGVETWCSLHV 523
Query: 1079 DWDKEVEKASSRLDQ 1123
+WD VE A+ + D+
Sbjct: 524 NWDHLVELANRQFDE 538
>sp|A4IIS8|S47A1_XENTR Multidrug and toxin extrusion protein 1 OS=Xenopus
tropicalis GN=slc47a1 PE=2 SV=1
Length = 574
Score = 181 bits (459), Expect = 1e-044
Identities = 103/381 (27%), Positives = 198/381 (51%), Gaps = 2/381 (0%)
Frame = +2
Query: 5 GAHRYDMLGVYLQRSTVVLIITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLPV 184
G ++G+ LQR ++L++ C P L + ++ +L + +V+ + ++V LP
Sbjct: 119 GGSNLKLVGIILQRGILILLLFCFPCWALLINTESILLLFRQDPEVSKLTQIYVLIFLPA 178
Query: 185 IFAYAVNFPIQKFLQAQSIVTPSAYISAAALVIHLVLSWVAVYRLGLGLLALSLVHSFSW 364
+ A + + K+LQ Q I+ P A + + + +++ +Y LGLG++ + ++ S
Sbjct: 179 LPAAFLYQLLAKYLQNQGIIYPQVLTGFIANIFNALFNYILLYVLGLGVMGSACANTVSQ 238
Query: 365 WIIVGAQIVYIKMSPRCRRSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILVLLA 544
+I + +YI +W G+S FE F RL+ AS +MLC+E W +I + LA
Sbjct: 239 FIQMILLFLYIVWRRLYADTWGGWSQACFEEWGAFIRLAVASMLMLCIEWWAFEISMFLA 298
Query: 545 GLLRDPEIALDSLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVTTSV 724
G+L ++A + AI ++ V +++ +G A S+RV + LGAGN A S +V +
Sbjct: 299 GVLGMVDLA--AQAIIYQVAIVVYLIPLGLCIAGSIRVGHGLGAGNTEQAKRSALVVLCM 356
Query: 725 SFLLAVFEAIVVMSWRNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVAVGC 904
+ L A+ I++ + ++V++Y+FT P + V+ + P + ++ + G+ G
Sbjct: 357 TELCALLSGILLATLKDVVAYIFTSDPNIVALVSYVLPVYSACLLFDACVAACGGILRGS 416
Query: 905 GWQAFVAYVNIGCYYVVGIPIGFVLGFTYDMGAKGIWTGMIGGTLMQTIILVVVTLRTDW 1084
G A + YYV+G+P+G L F +G G W G++ + Q+I L++ + DW
Sbjct: 417 GKLKVGAISHTVGYYVIGLPLGISLMFAAKLGIIGFWFGILACGIAQSIFLIIFVFKIDW 476
Query: 1085 DKEVEKASSRLDQWEESRERL 1147
+ E+A +R + E +++
Sbjct: 477 KRASEEAQTRASERVEIPQKI 497
>sp|Q96FL8|S47A1_HUMAN Multidrug and toxin extrusion protein 1 OS=Homo sapiens
GN=SLC47A1 PE=1 SV=1
Length = 570
Score = 181 bits (458), Expect = 1e-044
Identities = 108/368 (29%), Positives = 194/368 (52%), Gaps = 2/368 (0%)
Frame = +2
Query: 2 HGAHRYDMLGVYLQRSTVVLIITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLP 181
+G+ +GV LQRS +VL++ C P LF+ ++ +L + V+ + +V +P
Sbjct: 104 YGSQNLKHVGVILQRSALVLLLCCFPCWALFLNTQHILLLFRQDPDVSRLTQTYVTIFIP 163
Query: 182 VIFAYAVNFPIQKFLQAQSIVTPSAYISAAALVIHLVLSWVAVYRLGLGLLALSLVHSFS 361
+ A + K+L Q IV P AA +++ + +++ +++L LG++ +L + S
Sbjct: 164 ALPATFLYMLQVKYLLNQGIVLPQIVTGVAANLVNALANYLFLHQLHLGVIGSALANLIS 223
Query: 362 WWIIVGAQIVYIKMSPRCRRSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILVLL 541
+ + +YI + +W G+S + + F RL+ S +MLC+E W ++ L
Sbjct: 224 QYTLALLLFLYILGKKLHQATWGGWSLECLQDWASFLRLAIPSMLMLCMEWWAYEVGSFL 283
Query: 542 AGLLRDPEIALDSLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVTTS 721
+G+L E+ S I ++ + +MV GF+ AASVRV N LGAG+ A S+ V+
Sbjct: 284 SGILGMVELGAQS--IVYELAIIVYMVPAGFSVAASVRVGNALGAGDMEQARKSSTVSLL 341
Query: 722 VSFLLAVFEAIVVMSWRNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVAVG 901
++ L AV +++++S ++ + Y+FT + VA + P A++ + + GV G
Sbjct: 342 ITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVAQVVPIYAVSHLFEALACTSGGVLRG 401
Query: 902 CGWQAFVAYVNIGCYYVVGIPIGFVLGFTYDMGAKGIWTGMIGGTLMQTIILVVVTLRTD 1081
G Q A VN YYVVG+PIG L F +G G+W+G+I T+ Q + + ++ +
Sbjct: 402 SGNQKVGAIVNTIGYYVVGLPIGIALMFATTLGVMGLWSGIIICTVFQAVCFLGFIIQLN 461
Query: 1082 WDKEVEKA 1105
W K ++A
Sbjct: 462 WKKACQQA 469
>sp|Q5I0E9|S47A1_RAT Multidrug and toxin extrusion protein 1 OS=Rattus
norvegicus GN=Slc47a1 PE=1 SV=1
Length = 566
Score = 180 bits (456), Expect = 2e-044
Identities = 105/368 (28%), Positives = 193/368 (52%), Gaps = 2/368 (0%)
Frame = +2
Query: 2 HGAHRYDMLGVYLQRSTVVLIITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLP 181
+G+ +GV LQR T++L++ C P LF+ ++ +L + V+ + +V +P
Sbjct: 103 YGSQNLKHVGVILQRGTLILLLCCFPCWALFINTEQILLLFRQDPDVSRLTQTYVMVFIP 162
Query: 182 VIFAYAVNFPIQKFLQAQSIVTPSAYISAAALVIHLVLSWVAVYRLGLGLLALSLVHSFS 361
+ A + K+L Q IV P AA +++ + +++ +++L LG++ +L ++ S
Sbjct: 163 ALPAAFLYTLQVKYLLNQGIVLPQVITGIAANLVNALANYLFLHQLHLGVMGSALANTIS 222
Query: 362 WWIIVGAQIVYIKMSPRCRRSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILVLL 541
+ + +YI +W G+SW+ + F +L+ S +MLC+E W ++ L
Sbjct: 223 QFALAIFLFLYILWRKLHHATWGGWSWECLQDWASFLQLAIPSMLMLCIEWWAYEVGSFL 282
Query: 542 AGLLRDPEIALDSLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVTTS 721
+G+L E+ S I ++ + +M+ GF+ AA+VRV N LGAGN A S+ ++
Sbjct: 283 SGILGMVELGAQS--ITYELAIIVYMIPAGFSVAANVRVGNALGAGNIDQAKKSSAISLI 340
Query: 722 VSFLLAVFEAIVVMSWRNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVAVG 901
V+ L AV ++++ ++++ Y+FT + VA + P A++ + + GV G
Sbjct: 341 VTELFAVTFCVLLLGCKDLVGYIFTTDWDIVALVAQVVPIYAVSHLFEALACTCGGVLRG 400
Query: 902 CGWQAFVAYVNIGCYYVVGIPIGFVLGFTYDMGAKGIWTGMIGGTLMQTIILVVVTLRTD 1081
G Q A VN YYV+G+PIG L F +G G+W+G+I ++ QT +V R +
Sbjct: 401 TGNQKVGAIVNAIGYYVIGLPIGISLMFVAKLGVIGLWSGIIICSVCQTSCFLVFIARLN 460
Query: 1082 WDKEVEKA 1105
W ++A
Sbjct: 461 WKLACQQA 468
>sp|Q5RFD2|S47A1_PONAB Multidrug and toxin extrusion protein 1 OS=Pongo abelii
GN=SLC47A1 PE=2 SV=1
Length = 570
Score = 178 bits (449), Expect = 1e-043
Identities = 106/368 (28%), Positives = 191/368 (51%), Gaps = 2/368 (0%)
Frame = +2
Query: 2 HGAHRYDMLGVYLQRSTVVLIITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLP 181
+G+ +GV LQRS ++L++ C P LF+ ++ +L + V+ + +V +P
Sbjct: 104 YGSQNLKHVGVILQRSALILLLCCFPCWALFLNTQHILLLFRQDPDVSRLTQTYVTIFIP 163
Query: 182 VIFAYAVNFPIQKFLQAQSIVTPSAYISAAALVIHLVLSWVAVYRLGLGLLALSLVHSFS 361
+ A + K+L Q IV P AA +++ + +++ +++L LG + +L + S
Sbjct: 164 ALPATFLYMLQVKYLLNQGIVLPQIVTGVAANLVNALANYLFLHQLHLGAIGSALANLIS 223
Query: 362 WWIIVGAQIVYIKMSPRCRRSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILVLL 541
+ + YI + +W G+S + + F L+ S +MLC+E W ++ L
Sbjct: 224 QYTLALLLFFYILGKKLHQATWGGWSLECLQDWASFLHLAVPSMLMLCMEWWAYEVGSFL 283
Query: 542 AGLLRDPEIALDSLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVTTS 721
+G+L E+ S I ++ + +MV GF+ AASVRV N LGAG+ A S+ V+
Sbjct: 284 SGILGMVELGAQS--IVYELAIIVYMVPAGFSVAASVRVGNALGAGDMEQARKSSTVSLL 341
Query: 722 VSFLLAVFEAIVVMSWRNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVAVG 901
++ L AV +++++S ++ + Y+FT + VA + P A++ + + GV G
Sbjct: 342 ITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVAQVVPIYAVSHLFEALACTSGGVLRG 401
Query: 902 CGWQAFVAYVNIGCYYVVGIPIGFVLGFTYDMGAKGIWTGMIGGTLMQTIILVVVTLRTD 1081
G Q A VN YYVVG+PIG L F +G G+W+G+I T+ Q + + ++ +
Sbjct: 402 SGNQKVGAIVNTIGYYVVGLPIGIALMFATKLGVMGLWSGIIICTVFQAVCFLGFIIQLN 461
Query: 1082 WDKEVEKA 1105
W K ++A
Sbjct: 462 WKKACQQA 469
>sp|Q3V050|S47A2_MOUSE Multidrug and toxin extrusion protein 2 OS=Mus musculus
GN=Slc47a2 PE=1 SV=1
Length = 573
Score = 176 bits (444), Expect = 6e-043
Identities = 110/371 (29%), Positives = 191/371 (51%), Gaps = 4/371 (1%)
Frame = +2
Query: 5 GAHRYDMLGVYLQRSTVVLIITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLPV 184
G +GV LQR ++L++ C P +F+ ++ LL L + VA +A ++V +P
Sbjct: 114 GGKNLKRVGVILQRGILILLLCCFPCWAIFLNTERLLLLLRQDPDVARLAQVYVMICIPA 173
Query: 185 IFAYAVNFPIQ-KFLQAQSIVTPSAYISAAALVIHLVLSWVAVYRLGLGLLALSLVHSFS 361
+ A A F +Q ++LQ+Q I+ P + AA V+++ ++ +Y L LG++ + ++ S
Sbjct: 174 LPA-AFLFQLQTRYLQSQGIIMPQVIVGIAANVVNVGMNAFLLYALDLGVVGSAWANTTS 232
Query: 362 WWIIVGAQIVYIKMSPRCRRSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILVLL 541
+ + +Y+ +W G++ + F+ + RL+ S M+C+E W +I L
Sbjct: 233 QFFLSALLFLYVWWKRIHIHTWGGWTRECFQEWSSYTRLAIPSMFMVCIEWWTFEIGTFL 292
Query: 542 AGLLRDPEIALDSLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVTTS 721
AGL+ E L + A+ +++V++MV GF AASVRV N LGAGN A S
Sbjct: 293 AGLVNVTE--LGAQAVIYELASVAYMVPFGFGVAASVRVGNALGAGNADQARCSCTTVLL 350
Query: 722 VSFLLAVFEAIVVMSWRNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVAVG 901
+ + A+ I++ + ++V++Y+FT+ + V+ + P A + + + GV G
Sbjct: 351 CAGVCALLVGILLAALKDVVAYIFTNDKDIISLVSQVMPIFAPFHLFDALAGTCGGVLRG 410
Query: 902 CGWQAFVAYVNIGCYYVVGIPIGFVLGFTYDMGAKGIWTGMIGGTLMQTIILVVVTLRTD 1081
G Q A +N YY G PIG L F +G G+W G+I Q ++ LRT+
Sbjct: 411 TGKQKIGAVLNTIGYYGFGFPIGVSLMFAAKLGIIGLWAGLIVCVSFQAFSYLIYILRTN 470
Query: 1082 WDKEVEKASSR 1114
W + E+A R
Sbjct: 471 WSRVAEQAQVR 481
>sp|Q10085|YAO6_SCHPO Uncharacterized transporter C11D3.06
OS=Schizosaccharomyces pombe GN=SPAC11D3.06 PE=2 SV=1
Length = 455
Score = 161 bits (406), Expect = 1e-038
Identities = 109/379 (28%), Positives = 182/379 (48%), Gaps = 10/379 (2%)
Frame = +2
Query: 5 GAHRYDMLGVYLQRSTVVLIITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLPV 184
GA + LG+ LQ +VL I LP+ L++ +SKP+L L + ++A + F+ ++P
Sbjct: 78 GAGKKQELGILLQTGFIVLSILYLPICLVWWYSKPILIFLHQTPELAEASQKFLRYLIPG 137
Query: 185 IFAYAVNFPIQKFLQAQSIVTPSAYISAAALVIHLVLSWVAVYRLGLGLLALSLVHSFSW 364
Y ++KFLQ Q I +YI +++ L+++ V+ GLGL L S+
Sbjct: 138 GLGYVCFELLKKFLQTQEITRAGSYILLVTSPLNVALNFLLVHYYGLGLKGAPLATGLSY 197
Query: 365 W---IIVGAQIVYIKMSPRCRRSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILV 535
W I++ Y+K + +W G++ + E F +LS VM+ E W +I+
Sbjct: 198 WLSFILLTQYAKYVKGA----EAWNGWNKRCLENFGPFVKLSLLGIVMVGTEWWAFEIVA 253
Query: 536 LLAGLLRDPEIALDSLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVT 715
L+AG L +A S + M+ + + G S RV+ LGAG P A+ + V
Sbjct: 254 LVAGKLGAVPLAAQS--VIMTTDQLLNTIPFGLGIITSNRVAYYLGAGLPDNASLTAKVA 311
Query: 716 TSVSFLLAVFEAIVVMSWRNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVA 895
V + I +++ RN+ +FT+ P V + VA + P +A + + + + G
Sbjct: 312 AIVGVAVGSVIMITMIAVRNIYGRIFTNDPDVIQLVALVMPLVAAFQISDSLNGTMGGAL 371
Query: 896 VGCGWQAFVAYVNIGCYYVVGIPIGFVLGFTYDMGAKGIWTGMIGGTLMQTIILVVVTLR 1075
G G Q A VNI YY+ +P+G L F + G G+W G + + I+ + + +
Sbjct: 372 RGTGRQKVGAIVNITAYYLFALPLGIYLAF-HGKGLVGLWIGQVIALSIVGILELKIVMA 430
Query: 1076 TDWDKEVEKASSRLDQWEE 1132
TDW + KA SR E
Sbjct: 431 TDWISQSRKAISRFGDSSE 449
>sp|Q9UT92|YL47_SCHPO Uncharacterized transporter C323.07c
OS=Schizosaccharomyces pombe GN=SPAC323.07c PE=1 SV=1
Length = 533
Score = 156 bits (392), Expect = 6e-037
Identities = 100/373 (26%), Positives = 189/373 (50%), Gaps = 5/373 (1%)
Frame = +2
Query: 5 GAHRYDMLGVYLQRSTVVLIITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLPV 184
GA++ + +YLQR ++L + +P++L+++ + +L L + VA + ++ +
Sbjct: 161 GANKPYNVAIYLQRCLLILAVLHIPVALIWLNLEHILIFLHQDPMVAHLCGRYMRVFILA 220
Query: 185 IFAYAVNFPIQKFLQAQSIVTPSAYISAAALVIHLVLSWVAVYR--LGLGLLALSLVHSF 358
YAV ++++LQAQ I TP Y+ A ++++L+++ V+ +G G L + +
Sbjct: 221 APGYAVFEALKRYLQAQGIFTPITYVLCFAAPLNILLNYLLVWHPTIGFGFLGAPVAVAT 280
Query: 359 SWWIIVGAQIVYIKMSPRCRRSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILVL 538
++W I+YI S W GFS +A + L S +M+ E ++ L
Sbjct: 281 TFWFQSICLILYICFS-STPIPWPGFSRQALKNLSPMLHFSFHGMLMIVTEWAAYEMTSL 339
Query: 539 LAGLLRDPEIALDSLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVTT 718
AG L +A S +I ++ +++ F + F A+S RV + +G+G A + V
Sbjct: 340 GAGYLGTAPLA--SQSILLTSTSLLFQIPFAFAVASSTRVGHLIGSGRANLARLCSRVAY 397
Query: 719 SVSFLLAVFEAIVVMSWRNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVAV 898
S++ +++F+ ++ +R+V +FT P V V D+ P L++ IV +G+ V G+
Sbjct: 398 SLALCISIFDGSLIFCFRDVWGSLFTSDPEVLAVVKDIFPILSLFIVTDGLNAVGGGLLR 457
Query: 899 GCGWQAFVAYVNIGCYYVVGIPIGFVLGFTYDMGAKGIWTGMIGGTLMQTIILVVVTLRT 1078
G G Q ++IG Y+ +P+ + ++ G KGIW GMI ++ V T
Sbjct: 458 GTGKQYIGGLISIGSSYLFALPVTVFVVVYFNTGLKGIWCGMILSSVTAITCQFTVLFNT 517
Query: 1079 DWDKEVEKASSRL 1117
DW + +++A RL
Sbjct: 518 DWHRVLQEARHRL 530
>sp|Q05497|YD338_YEAST Uncharacterized transporter YDR338C OS=Saccharomyces
cerevisiae GN=YDR338C PE=1 SV=1
Length = 695
Score = 146 bits (367), Expect = 5e-034
Identities = 90/365 (24%), Positives = 182/365 (49%), Gaps = 5/365 (1%)
Frame = +2
Query: 2 HGAHRYDMLGVYLQRSTVVLIITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLP 181
+G+ R+ +GV+LQR ++ +P ++++ +S+PLL+ + +++ ++ S F+ ++
Sbjct: 297 YGSGRFYSVGVHLQRCIAFSLVIYIPFAVMWWYSEPLLSYIIPEKELINLTSRFLRVLIL 356
Query: 182 VIFAYAVNFPIQKFLQAQSIVTPSAYISAAALVIHLVLSWVAVYR--LGLGLLALSLVHS 355
AY +++FLQAQ I Y+ +++++S+ V+ +G+G + ++
Sbjct: 357 GAPAYIFFENLKRFLQAQGIFDAGIYVLTICAPLNVLVSYTLVWNKYIGVGFIGAAIAVV 416
Query: 356 FSWWIIVGAQIVYIKMSPRCRRSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILV 535
++W++ + Y + R+ W GFS KAF D L+ + +ML E ++L
Sbjct: 417 LNFWLMFFLLLFY-ALYIDGRKCWGGFSRKAFTHWNDLGHLAFSGIIMLEAEELSYELLT 475
Query: 536 LLAGLLRDPEIALDSLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVT 715
L + +A S M +A+ +M+ + S R++N +GA A S+ V
Sbjct: 476 LFSAYYGVSYLAAQSAVSTM--AALLYMIPFAIGISTSTRIANFIGAKRTDFAHISSQVG 533
Query: 716 TSVSFLLAVFEAIVVMSWRNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVA 895
S SF+ +++ RN+++ +++ P V + +A + P + I + + V
Sbjct: 534 LSFSFIAGFINCCILVFGRNLIANIYSKDPEVIKLIAQVLPLVGIVQNFDSLNAVAGSCL 593
Query: 896 VGCGWQAFVAYVNIGCYYVVGIPIGFVLGFTYDMGAKGIWTGMIGGTLMQTIILVVVTLR 1075
G G Q+ + VN+ YY+ GIP+ +L + +DM G+W G+ L+ ++ L
Sbjct: 594 RGQGMQSLGSIVNLMAYYLFGIPLALILSWFFDMKLYGLWIGIGSAMLLIGLVEAYYVLF 653
Query: 1076 TDWDK 1090
DWDK
Sbjct: 654 PDWDK 658
>sp|Q98D15|NORM_RHILO Probable multidrug resistance protein norM OS=Rhizobium
loti GN=norM PE=3 SV=1
Length = 467
Score = 101 bits (250), Expect = 2e-020
Identities = 93/359 (25%), Positives = 164/359 (45%), Gaps = 29/359 (8%)
Frame = +2
Query: 62 IITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLPVIFAYAVNFPIQKFLQAQSI 241
I+ +P+ ++ + +L +G+ +A A +++ + + + ++ F+ A
Sbjct: 109 ILISIPIWIVLWHGEAILLAMGQEPALAHQAGIYLRWLEWAVLPFYGYIVLRSFISALER 168
Query: 242 VTPSAYISAAALVIHLVLSWVAVY-RLG---LGLLALSLVHSFSWWIIVGAQIVYIKMSP 409
+ I A+ + + +WV ++ LG +G+ L S S ++ + +
Sbjct: 169 PGWALIIVFVAVACNALFNWVFMFGNLGFPAMGIAGSGLATSLSSTLMFAGMAAVVMLEK 228
Query: 410 RCR------RSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILVLLAGLLRDPEIA 571
+ R R W W F GL RL A +L E LL GL+ +A
Sbjct: 229 KFRRYRLFGRFWRS-DWPRFNGL---LRLGLPIAGILAFEVTIFNAAALLMGLIDADSLA 284
Query: 572 LDSLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFS--TVVTTSVSFLLAVF 745
++AI I+++SFMV +G N A +VRV GAGNP + + T VSF+ +
Sbjct: 285 AHAIAI--QIASISFMVPLGLNQAVTVRVGLAHGAGNPEGVSRAGWTAFVIGVSFMALM- 341
Query: 746 EAIVVMSWRNVLSYMFTD------SPIVAEAVADLSPFLAITIVLNGIQPVLSGVAVGC- 904
+V++ W ++L F D + ++A AV+ L F A+ V +G Q V +G+ G
Sbjct: 342 -GLVMVLWPHLLISAFIDLANPANARVIALAVSFL-VFAALFQVFDGAQAVAAGMLRGLH 399
Query: 905 GWQAFVAYVNIGCYYVVGIPIGFVLGFTYDMGAKGIWTGMIGGTLMQTIILVVVTLRTD 1081
+ + Y IG Y+ VG+P+G +L F + GIW G+ G + +L+ LR D
Sbjct: 400 DTKVPMIYAAIG-YWGVGLPLGVLLAFHFGFHGVGIWIGLSSGLAVVAALLLTRWLRRD 457
>sp|A6TA11|MDTK_KLEP7 Multidrug resistance protein mdtK OS=Klebsiella pneumoniae
subsp. pneumoniae (strain ATCC 700721 / MGH 78578) GN=mdtK PE=3 SV=1
Length = 457
Score = 86 bits (212), Expect = 5e-016
Identities = 68/282 (24%), Positives = 130/282 (46%), Gaps = 12/282 (4%)
Frame = +2
Query: 248 PSAYISAAALVIHLVLSWVAVY-RLG---LGLLALSLVHSFSWWIIVGAQIVYIKMSPRC 415
P + L++++ ++++ +Y G LG + + + +W++ + + +++ +
Sbjct: 159 PGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATASVYWVMFASMLWWVRRARTM 218
Query: 416 R--RSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILVLLAGLLRDPEIALDSLAI 589
R R E FS F L +L A+ L E ++ LL L ++A +A
Sbjct: 219 RDIRCAERFSGPDFAVLLRLVQLGLPIALALFFEVTLFAVVALLVSPLGIIDVAGHQIA- 277
Query: 590 CMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVTTSVSFLLAVFEAIVVMSW 769
++ S++ F++ + AA ++RV LG G+ A S V LAVF AI +
Sbjct: 278 -LNFSSLMFVLPLSLAAAVTIRVGFRLGQGSTIDAQVSARTGVGVGVCLAVFTAIFTVLM 336
Query: 770 RNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVAVGCGWQAFVAYVNIGCYY 949
R ++ ++ D+P V + L AI + + IQ + SG+ G + ++ Y+
Sbjct: 337 RKQIALLYNDNPEVVTLASHLMLLAAIYQISDSIQVIGSGILRGYKDTRSIFFITFTAYW 396
Query: 950 VVGIPIGFVLGFT----YDMGAKGIWTGMIGGTLMQTIILVV 1063
V+G+P G++L T MG G W G I G I++++
Sbjct: 397 VLGLPSGYLLALTDMIVPRMGPAGFWCGFIIGLTSAAIMMML 438
>sp|B5XWL3|MDTK_KLEP3 Multidrug resistance protein mdtK OS=Klebsiella pneumoniae
(strain 342) GN=mdtK PE=3 SV=1
Length = 457
Score = 82 bits (202), Expect = 7e-015
Identities = 67/282 (23%), Positives = 129/282 (45%), Gaps = 12/282 (4%)
Frame = +2
Query: 248 PSAYISAAALVIHLVLSWVAVY-RLG---LGLLALSLVHSFSWWIIVGAQIVYIKMSPRC 415
P + L++++ ++++ +Y G LG + + + +W++ + + +++ +
Sbjct: 159 PGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATASVYWVMFASMLWWVRRARSM 218
Query: 416 R--RSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILVLLAGLLRDPEIALDSLAI 589
R R E FS L +L A+ L E ++ LL L ++A +A
Sbjct: 219 RDIRCAERFSRPDVAVLLRLVQLGLPIALALFFEVTLFAVVALLVSPLGIIDVAGHQIA- 277
Query: 590 CMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVTTSVSFLLAVFEAIVVMSW 769
++ S++ F++ + AA ++RV LG G+ A S V LAVF AI +
Sbjct: 278 -LNFSSLMFVLPLSLAAAVTIRVGFRLGQGSTIDAQVSARTGVGVGVCLAVFTAIFTVLM 336
Query: 770 RNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVAVGCGWQAFVAYVNIGCYY 949
R ++ ++ D+P V + L AI + + IQ + SG+ G + ++ Y+
Sbjct: 337 REQIALLYNDNPEVVLLASHLMLLAAIYQISDSIQVIGSGILRGYKDTRSIFFITFTAYW 396
Query: 950 VVGIPIGFVLGFT----YDMGAKGIWTGMIGGTLMQTIILVV 1063
V+G+P G++L T MG G W G I G I++++
Sbjct: 397 VLGLPSGYLLALTDMVVPRMGPAGFWCGFIIGLTSAAIMMML 438
>sp|Q9I3Y3|PMPM_PSEAE Multidrug resistance protein pmpM OS=Pseudomonas
aeruginosa GN=pmpM PE=3 SV=1
Length = 477
Score = 80 bits (196), Expect = 3e-014
Identities = 65/287 (22%), Positives = 125/287 (43%), Gaps = 12/287 (4%)
Frame = +2
Query: 248 PSAYISAAALVIHLVLSWVAVY-RLGLGLLALS----LVHSFSWWIIVGAQIVYIKMS-P 409
PS + L++++ +++ +Y G+ + S W++ +G K S
Sbjct: 169 PSMVLGIGGLLLNIPINYALIYGHFGMPKMGGPGCGWATGSVMWFMFLGMLFWVNKASIY 228
Query: 410 RCRRSWEGFSWKAFEGLWDFFRLSAASAVMLCLESWYSQILVLLAGLLRDPEIALDSLAI 589
R + + + W + + + + ES ++ LL G L + +A +A
Sbjct: 229 RASQLFSRWEWPDRATIGPLVAVGLPIGIAVFAESSIFSVIALLIGGLDENVVAGHQIA- 287
Query: 590 CMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVTTSVSFLLAVFEAIVVMSW 769
++ SA+ FM+ A +VRV + LGAG PR A F+ V + + A A +++
Sbjct: 288 -LNFSALVFMIPYSLGMAVTVRVGHNLGAGLPRDARFAAGVGMAAALGYACVSASLMLLL 346
Query: 770 RNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVAVGCGWQAFVAYVNIGCYY 949
R ++ M++ P V A L F A+ + +Q +G G + + Y+
Sbjct: 347 REQIAAMYSPDPAVIAIAASLIVFSALFQFSDALQVTAAGALRGYQDTRVTMIMTLFAYW 406
Query: 950 VVGIPIGFVLG----FTYDMGAKGIWTGMIGGTLMQTIILVVVTLRT 1078
+G+P+G+ LG F G +G+W G++ G I+L + R+
Sbjct: 407 GIGLPVGYSLGLTDWFQEPTGPRGLWQGLVVGLTGAAIMLCIRLARS 453
>sp|Q7NXN3|NORM_CHRVO Probable multidrug resistance protein norM
OS=Chromobacterium violaceum GN=norM PE=3 SV=1
Length = 465
Score = 75 bits (184), Expect = 8e-013
Identities = 80/352 (22%), Positives = 148/352 (42%), Gaps = 18/352 (5%)
Frame = +2
Query: 59 LIITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLPVIFAYAVNFPIQKFLQAQS 238
L++ L L+ + PL + L P V LF+ G + A + + + A S
Sbjct: 105 LMLGALGAGLMLLLEAPLRHWLHLPPDVTDKVMLFITGAAIGMPAAMAHRALHAY--ASS 162
Query: 239 IVTPSA--YISAAALVIHLVLSWVAVYRL----GLGLLALSLVHSFSWWIIVGAQIVYIK 400
+ P A +S AL +++ L+++ ++ L +G +W A + Y+
Sbjct: 163 LGHPKAIMVVSLLALALNIPLNYILIHGLFGMPRMGGAGCGWATGIVFWFNCLALLTYVS 222
Query: 401 MSPRCR--RSWEGFSWKAFEGLWDFFRLSAASAVMLCLE-SWYSQILVLLAGLLRDPEIA 571
R R G + + F +L + +E S +S I +L+A L +
Sbjct: 223 WHRHFRDSRILAGLAAPDWRRFLAFLKLGVPIGLSFFVEVSLFSFIALLIAEL---GTVV 279
Query: 572 LDSLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFSTVVTTSVSFLLAVFEA 751
+ + ++ S++ +M+ A SVRV + GAG+ RAA F + V + +A
Sbjct: 280 VATHQSVLNFSSLIYMLPQSVATALSVRVGHHAGAGDYRAARFISGVGMLMGLAMAGGAM 339
Query: 752 IVVMSWRNVLSYMFTDSPIVAEAVADLSPFLAITIVLNGIQPVLSGVAVGCGWQAFVAYV 931
+V+ R + +M++ P V L F A+ + + Q + SG G A +
Sbjct: 340 ALVLLLREPIMWMYSADPRVIAMGTTLLLFAAVYQLTDAAQTIASGALRGYKLTAVPMLI 399
Query: 932 NIGCYYVVGIPIGFVLGFT----YDMGAKGIWTGMIGGTLMQTIILVVVTLR 1075
+I ++V G+ +G +LG T MG G WT ++ + ++L R
Sbjct: 400 HITSFWVAGLGLGMLLGLTDWIVPRMGIYGFWTALVISLTVAGLLLTYYLAR 451
>sp|Q8YFD7|NORM_BRUME Probable multidrug resistance protein norM OS=Brucella
melitensis GN=norM PE=3 SV=1
Length = 471
Score = 55 bits (130), Expect = 1e-006
Identities = 52/244 (21%), Positives = 113/244 (46%), Gaps = 14/244 (5%)
Frame = +2
Query: 62 IITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLPVIFAYAVNFPIQKFLQAQSI 241
I+ +P+ ++ + + LG+ +A+ ++ F++ + + Y ++ F A
Sbjct: 114 IMIVIPLWVVLWHCEEIFLFLGQRPDIAARSTDFMHTLQWALLPYLFYIVLRSFFAAMEK 173
Query: 242 VTPSAYISAAALVIHLVLSWVAVY------RLGLGLLALSLVHSFSWWIIVGAQIVYIKM 403
+ ++A A+ + + W ++ +GL ++ S S + +G + ++
Sbjct: 174 PMWTLLVAALAIGFNALAGWTLIFGHFGFAPMGLHGAGMATTAS-STMMFLGLAFITLR- 231
Query: 404 SPRCRR-SWEGFSWKA-FEGLWDFFRLSAASAVMLCLESWYSQILVLLAGLLRDPEIALD 577
PR RR G W+ + L + +R+ A+ E+ V++ G R A+
Sbjct: 232 HPRFRRYHLFGRFWRPDWPRLIELWRIGLPMALTFVFETSIFYAAVVMMG--RIGPTAMA 289
Query: 578 SLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFS--TVVTTSVSFLLAVFEA 751
+ A+ + I+++SFMV +GF A+VRV G G+P+A A++ + V F+ +
Sbjct: 290 AHAVAIQIASLSFMVPLGFGQVATVRVGRAYGRGDPKAIAYAGWSAYALGVGFMALMGIL 349
Query: 752 IVVM 763
+V+M
Sbjct: 350 MVLM 353
>sp|Q8G2I1|NORM_BRUSU Probable multidrug resistance protein norM OS=Brucella
suis GN=norM PE=3 SV=1
Length = 471
Score = 55 bits (130), Expect = 1e-006
Identities = 52/244 (21%), Positives = 113/244 (46%), Gaps = 14/244 (5%)
Frame = +2
Query: 62 IITCLPMSLLFVFSKPLLNTLGEPEQVASMASLFVYGMLPVIFAYAVNFPIQKFLQAQSI 241
I+ +P+ ++ + + LG+ +A+ ++ F++ + + Y ++ F A
Sbjct: 114 IMIVIPLWVVLWHCEEIFLFLGQRPDIAARSTDFMHTLQWALLPYLFYIVLRSFFAAMEK 173
Query: 242 VTPSAYISAAALVIHLVLSWVAVY------RLGLGLLALSLVHSFSWWIIVGAQIVYIKM 403
+ ++A A+ + + W ++ +GL ++ S S + +G + ++
Sbjct: 174 PMWTLLVAALAIGFNALAGWTLIFGHFGFAPMGLHGAGMATTAS-STMMFLGLAFITLR- 231
Query: 404 SPRCRR-SWEGFSWKA-FEGLWDFFRLSAASAVMLCLESWYSQILVLLAGLLRDPEIALD 577
PR RR G W+ + L + +R+ A+ E+ V++ G R A+
Sbjct: 232 HPRFRRYHLFGRFWRPDWPRLIELWRIGLPMALTFVFETSIFYAAVVMMG--RIGPTAMA 289
Query: 578 SLAICMSISAVSFMVSVGFNAAASVRVSNELGAGNPRAAAFS--TVVTTSVSFLLAVFEA 751
+ A+ + I+++SFMV +GF A+VRV G G+P+A A++ + V F+ +
Sbjct: 290 AHAVAIQIASLSFMVPLGFGQVATVRVGRAYGRGDPKAIAYAGWSAYALGVGFMALMGIL 349
Query: 752 IVVM 763
+V+M
Sbjct: 350 MVLM 353
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,894,514,945
Number of Sequences: 518415
Number of Extensions: 45894514945
Number of Successful Extensions: 338263929
Number of sequences better than 0.0: 0
|
